GREMLIN Database
YDBJ - Uncharacterized ABC transporter ATP-binding protein YdbJ
UniProt: P96605 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 308 (240)
Sequences: 74743 (45535)
Seq/√Len: 2939.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
32_E203_R3.6961.00
34_I205_I3.1091.00
19_Q22_K3.0541.00
79_A153_K3.0361.00
7_H27_D2.9801.00
126_A129_D2.8931.00
10_G23_Q2.8071.00
9_E61_S2.7191.00
14_K19_Q2.7021.00
35_G201_C2.6241.00
203_R215_E2.5381.00
13_K50_I2.4981.00
29_M32_E2.4541.00
7_H63_T2.4451.00
61_S68_Q2.3951.00
12_D59_S2.3371.00
217_S220_G2.2801.00
65_S153_K2.2771.00
12_D19_Q2.2171.00
216_V220_G2.2071.00
205_I212_I2.1541.00
22_K211_E2.1131.00
120_R183_E2.0911.00
12_D23_Q2.0201.00
8_I11_L2.0031.00
9_E63_T1.9771.00
205_I215_E1.9131.00
30_E153_K1.9091.00
115_D127_I1.9061.00
113_R151_R1.8681.00
96_W127_I1.8501.00
95_G134_Y1.7961.00
15_I46_T1.7691.00
113_R116_E1.7541.00
48_I190_A1.7281.00
129_D133_T1.7141.00
116_E120_R1.6961.00
15_I20_I1.6781.00
48_I156_I1.6781.00
198_E219_Q1.6361.00
65_S79_A1.5931.00
96_W128_H1.5721.00
151_R185_T1.5621.00
177_K199_D1.5581.00
13_K55_L1.5231.00
111_D115_D1.5201.00
96_W100_K1.5111.00
191_T197_V1.5031.00
13_K58_N1.4851.00
119_E124_T1.4821.00
100_K110_A1.4671.00
216_V221_T1.4661.00
12_D22_K1.4481.00
10_G25_S1.4361.00
72_E75_K1.4361.00
68_Q71_T1.4351.00
118_V127_I1.4261.00
8_I26_M1.4081.00
11_L57_Q1.3981.00
117_V149_L1.3961.00
26_M205_I1.3951.00
94_T97_E1.3811.00
99_L118_V1.3671.00
34_I215_E1.3661.00
93_L97_E1.3561.00
151_R183_E1.3541.00
67_F72_E1.3471.00
35_G197_V1.3441.00
220_G224_T1.3271.00
32_E202_D1.3141.00
14_K58_N1.2991.00
100_K114_L1.2771.00
24_I47_L1.2611.00
73_F77_M1.2501.00
157_L187_V1.2501.00
33_I180_A1.2441.00
104_N110_A1.2431.00
29_M203_R1.2411.00
26_M47_L1.2261.00
28_V34_I1.2101.00
96_W111_D1.1981.00
8_I51_I1.1841.00
63_T68_Q1.1781.00
9_E27_D1.1631.00
112_E116_E1.1571.00
126_A134_Y1.1571.00
117_V145_A1.1571.00
115_D119_E1.1551.00
100_K111_D1.1491.00
5_I65_S1.1491.00
52_V82_A1.1391.00
173_R196_E1.1361.00
53_G73_F1.1231.00
117_V121_V1.1221.00
94_T128_H1.1211.00
34_I203_R1.1181.00
50_I57_Q1.1161.00
208_Q213_K1.0951.00
36_L188_L1.0921.00
109_I112_E1.0921.00
177_K180_A1.0901.00
98_N146_Q1.0901.00
53_G56_K1.0861.00
122_G171_D1.0721.00
49_R55_L1.0691.00
30_E65_S1.0661.00
120_R178_E1.0651.00
36_L47_L1.0511.00
180_A187_V1.0391.00
33_I187_V1.0391.00
9_E25_S1.0381.00
21_L50_I1.0341.00
85_E136_L1.0291.00
219_Q223_Q1.0281.00
113_R117_V1.0261.00
33_I201_C1.0101.00
96_W114_L1.0071.00
100_K104_N1.0011.00
170_K174_D0.9961.00
180_A202_D0.9851.00
83_I157_L0.9801.00
164_L172_F0.9771.00
92_Y132_K0.9771.00
220_G223_Q0.9741.00
176_I187_V0.9741.00
116_E119_E0.9581.00
227_K230_I0.9571.00
103_A149_L0.9541.00
55_L58_N0.9531.00
121_V145_A0.9521.00
204_V218_L0.9511.00
225_T229_I0.9501.00
96_W115_D0.9491.00
169_M196_E0.9491.00
131_V142_L0.9491.00
109_I113_R0.9481.00
155_L185_T0.9471.00
175_H178_E0.9441.00
134_Y142_L0.9431.00
10_G59_S0.9421.00
115_D123_L0.9381.00
157_L176_I0.9261.00
103_A110_A0.9251.00
107_K110_A0.9211.00
106_H150_H0.9181.00
93_L98_N0.9151.00
169_M193_L0.9131.00
111_D127_I0.9111.00
8_I47_L0.9111.00
94_T130_K0.9091.00
228_A231_E0.9081.00
47_L207_I0.9081.00
99_L149_L0.9061.00
14_K17_S0.9001.00
212_I215_E0.8981.00
95_G142_L0.8941.00
49_R54_L0.8921.00
130_K133_T0.8901.00
231_E235_Q0.8861.00
110_A114_L0.8841.00
97_E100_K0.8831.00
108_K112_E0.8821.00
81_G152_P0.8821.00
122_G178_E0.8781.00
75_K78_E0.8761.00
67_F79_A0.8741.00
155_L187_V0.8661.00
94_T98_N0.8621.00
30_E184_G0.8611.00
230_I234_P0.8561.00
33_I177_K0.8561.00
117_V120_R0.8531.00
173_R199_D0.8521.00
83_I144_I0.8521.00
81_G147_A0.8491.00
177_K181_E0.8461.00
52_V156_I0.8421.00
126_A138_M0.8421.00
230_I233_Q0.8401.00
6_L51_I0.8361.00
208_Q232_V0.8331.00
159_E192_H0.8311.00
11_L50_I0.8131.00
174_D177_K0.8131.00
36_L205_I0.8081.00
14_K22_K0.8071.00
67_F75_K0.8051.00
83_I147_A0.8041.00
8_I62_V0.7971.00
50_I55_L0.7971.00
93_L101_H0.7961.00
177_K200_L0.7951.00
102_F146_Q0.7931.00
39_P208_Q0.7921.00
104_N107_K0.7901.00
98_N131_V0.7891.00
33_I189_F0.7881.00
134_Y138_M0.7871.00
124_T127_I0.7871.00
107_K111_D0.7841.00
110_A113_R0.7831.00
92_Y97_E0.7831.00
76_A80_V0.7831.00
13_K46_T0.7811.00
198_E222_D0.7801.00
218_L222_D0.7791.00
51_I188_L0.7781.00
28_V186_A0.7781.00
23_Q59_S0.7741.00
37_L197_V0.7661.00
89_F139_R0.7661.00
42_S207_I0.7651.00
239_L242_L0.7611.00
57_Q70_D0.7591.00
99_L114_L0.7511.00
24_I212_I0.7481.00
33_I200_L0.7481.00
29_M186_A0.7461.00
153_K185_T0.7441.00
241_W244_G0.7421.00
213_K227_K0.7411.00
111_D114_L0.7401.00
156_I188_L0.7371.00
198_E218_L0.7271.00
21_L47_L0.7211.00
228_A232_V0.7201.00
28_V154_L0.7201.00
50_I62_V0.7181.00
23_Q211_E0.7131.00
161_T172_F0.7121.00
189_F201_C0.7121.00
201_C204_V0.7121.00
214_A224_T0.7121.00
179_L185_T0.7111.00
21_L24_I0.7011.00
232_V235_Q0.6991.00
203_R214_A0.6961.00
118_V123_L0.6961.00
229_I233_Q0.6951.00
171_D174_D0.6921.00
37_L206_I0.6921.00
208_Q211_E0.6911.00
15_I55_L0.6861.00
180_A183_E0.6851.00
34_I188_L0.6831.00
117_V148_I0.6811.00
206_I221_T0.6791.00
13_K21_L0.6771.00
225_T228_A0.6761.00
20_I46_T0.6701.00
10_G13_K0.6691.00
112_E115_D0.6691.00
231_E234_P0.6661.00
75_K79_A0.6661.00
90_Y93_L0.6631.00
6_L154_L0.6601.00
218_L228_A0.6601.00
6_L64_I0.6551.00
61_S70_D0.6531.00
189_F200_L0.6491.00
196_E200_L0.6471.00
65_S154_L0.6431.00
5_I30_E0.6411.00
14_K20_I0.6401.00
80_V154_L0.6371.00
191_T196_E0.6351.00
114_L117_V0.6311.00
14_K59_S0.6311.00
102_F105_M0.6281.00
50_I58_N0.6271.00
232_V236_E0.6261.00
19_Q23_Q0.6221.00
27_D215_E0.6211.00
56_K70_D0.6201.00
174_D199_D0.6191.00
218_L221_T0.6181.00
81_G150_H0.6171.00
161_T196_E0.6141.00
102_F150_H0.6091.00
222_D225_T0.6091.00
101_H105_M0.6081.00
154_L188_L0.6061.00
33_I202_D0.6051.00
154_L186_A0.6041.00
135_S138_M0.6001.00
116_E151_R0.5991.00
174_D178_E0.5991.00
87_P143_G0.5981.00
54_L84_V0.5971.00
28_V188_L0.5971.00
103_A113_R0.5961.00
194_L222_D0.5961.00
64_I76_A0.5951.00
91_P132_K0.5951.00
45_T49_R0.5911.00
201_C218_L0.5901.00
5_I29_M0.5891.00
51_I62_V0.5871.00
63_T66_G0.5871.00
206_I225_T0.5861.00
221_T225_T0.5831.00
144_I172_F0.5801.00
49_R82_A0.5771.00
37_L194_L0.5771.00
5_I154_L0.5761.00
5_I64_I0.5731.00
64_I79_A0.5671.00
125_S129_D0.5661.00
111_D128_H0.5661.00
52_V80_V0.5661.00
221_T230_I0.5641.00
67_F76_A0.5571.00
83_I143_G0.5561.00
197_V204_V0.5551.00
168_G171_D0.5541.00
209_K232_V0.5511.00
102_F106_H0.5481.00
213_K228_A0.5481.00
195_R199_D0.5481.00
89_F98_N0.5471.00
61_S71_T0.5461.00
136_L141_R0.5451.00
91_P139_R0.5441.00
114_L127_I0.5421.00
203_R217_S0.5421.00
5_I186_A0.5411.00
240_N243_T0.5391.00
236_E239_L0.5371.00
76_A79_A0.5371.00
236_E240_N0.5351.00
214_A221_T0.5341.00
89_F131_V0.5341.00
14_K18_K0.5331.00
129_D134_Y0.5311.00
51_I156_I0.5301.00
73_F76_A0.5291.00
90_Y98_N0.5291.00
180_A184_G0.5281.00
112_E119_E0.5271.00
64_I154_L0.5261.00
30_E186_A0.5251.00
214_A225_T0.5251.00
101_H104_N0.5231.00
242_L245_N0.5231.00
131_V139_R0.5201.00
128_H131_V0.5181.00
197_V201_C0.5171.00
127_I130_K0.5161.00
140_Q163_G0.5161.00
123_L126_A0.5151.00
69_H76_A0.5151.00
18_K209_K0.5111.00
95_G99_L0.5101.00
11_L62_V0.5081.00
31_G186_A0.5061.00
53_G70_D0.5061.00
239_L243_T0.5041.00
224_T228_A0.5011.00
220_G226_E0.5011.00
40_N168_G0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4yerA 2 0.9123 100 0.134 Contact Map
3tuiC 2 0.9903 100 0.178 Contact Map
4u00A 1 0.763 100 0.2 Contact Map
1b0uA 2 0.776 100 0.2 Contact Map
2oljA 2 0.763 100 0.203 Contact Map
4mkiB 2 0.8669 100 0.203 Contact Map
4rvcA 4 0.7695 100 0.203 Contact Map
4ymuJ 2 0.7565 100 0.208 Contact Map
1v43A 2 0.9513 100 0.208 Contact Map
1g291 4 0.9058 100 0.21 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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