YDAP - BACSU - GREMLIN Contacts

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YDAP - Putative thiamine pyrophosphate-containing protein YdaP

UniProt:	P96591	Sequences: MAHKTAGQAMTELLEQWGVDHVYGIPGDSINEFIEELRHERNQLKFIQTRHEEVAALAAAAEAKLTGKIGVCLSIAGPGAVHLLNGLYDAKADGAPVLAIAGQVSSGEVGRDYFQEIKLEQMFEDVAVFNREVHSAESLPDLLNQAIRTAYSKKGVAVLSVSDDLFAEKIKREPVYTSPVYIEGNLEPKKEQLVTCAQYINNAKKPIILAGQGMKKAKRELLEFADKAAAPIVVTLPAKGVVPDKHPHFLGNLGQIGTKPAYEAMEECDLLIMLGTSFPYRDYLPDDTPAIQLDSDPAKIGKRYPVTAGLVCDSALGLRELTEYIERKEDRRFLNACTEHMQHWWNEIEKDETEATTPLKPQQVVARLQEAAADDAVLSVDVGTVTVWMARHFKMNANQDFIVSSWLATMGCGLPGAIAASLSEPERQAIAVCGDGGFSMVMQDLPTAVKYKLPITVVILNNENLGMIEYEQQVKGNIDYVTKLQNVDYAAFAESCGAKGIKVTKAEELAPAFHEALHSDQPVVVDVMIGNEPPLPGKITYGQAKGFSKYMLKNFFENQKFEMPSLKKSLKRLF	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	574 (530)
Sequences:	14311 (9197)
Seq/√Len:	399.5

ECOLI - POXB GCL ILVI ILVB ILVG OXC MEND
BACSU - YDAP ILVX IOLD ILVB MEND
HALSA - MEND
SULSO - Q97UP3 Q97ZB3 Q7LXT8 Q97U16 Q97V62 Q97XR3 Q980V7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
491_A	494_E	4.968	1.00
367_R	510_A	3.767	1.00
461_N	526_D	3.656	1.00
56_A	86_G	3.457	1.00
501_I	515_E	3.428	1.00
226_D	246_H	3.388	1.00
220_E	319_R	3.316	1.00
505_K	508_E	3.106	1.00
20_D	68_K	3.064	1.00
502_K	528_M	2.975	1.00
194_V	324_Y	2.952	1.00
371_A	514_H	2.843	1.00
220_E	315_A	2.740	1.00
15_E	43_Q	2.724	1.00
65_L	424_E	2.708	1.00
245_K	396_N	2.648	1.00
312_C	317_G	2.640	1.00
501_I	523_V	2.608	1.00
499_K	521_Q	2.569	1.00
210_A	221_L	2.552	1.00
367_R	370_E	2.473	1.00
21_H	45_K	2.452	1.00
504_T	508_E	2.444	1.00
501_I	512_A	2.315	1.00
196_C	291_I	2.312	1.00
417_A	431_A	2.296	1.00
274_L	314_S	2.274	1.00
74_S	83_L	2.256	1.00
488_D	491_A	2.227	1.00
502_K	526_D	2.178	1.00
69_I	151_Y	2.164	1.00
370_E	510_A	2.134	1.00
268_C	271_L	2.131	1.00
424_E	427_R	2.102	1.00
49_T	55_A	2.082	1.00
8_Q	36_E	2.081	1.00
273_M	276_T	2.078	1.00
499_K	515_E	2.067	1.00
87_L	99_A	2.022	1.00
293_L	317_G	2.010	1.00
121_Q	124_E	2.006	1.00
439_S	496_C	1.994	1.00
492_F	495_S	1.988	1.00
81_V	85_N	1.956	1.00
208_I	225_A	1.955	1.00
199_Y	270_L	1.954	1.00
98_L	147_I	1.944	1.00
199_Y	308_A	1.943	1.00
490_A	500_G	1.940	1.00
101_A	158_V	1.919	1.00
199_Y	289_P	1.901	1.00
12_E	16_Q	1.894	1.00
227_K	322_T	1.886	1.00
369_Q	394_K	1.882	1.00
503_V	512_A	1.868	1.00
200_I	272_I	1.851	1.00
142_L	159_L	1.849	1.00
514_H	518_H	1.837	1.00
373_A	376_A	1.834	1.00
190_K	320_E	1.829	1.00
333_F	337_C	1.807	1.00
438_F	442_M	1.780	1.00
195_T	198_Q	1.779	1.00
499_K	523_V	1.774	1.00
198_Q	202_N	1.765	1.00
227_K	326_E	1.760	1.00
421_S	454_P	1.756	1.00
69_I	98_L	1.753	1.00
223_E	227_K	1.750	1.00
225_A	232_I	1.738	1.00
189_K	192_Q	1.727	1.00
508_E	511_P	1.724	1.00
208_I	272_I	1.719	1.00
449_V	498_A	1.711	1.00
60_A	64_K	1.709	1.00
222_L	226_D	1.705	1.00
4_K	12_E	1.702	1.00
516_A	525_V	1.691	1.00
459_I	524_V	1.690	1.00
366_A	370_E	1.685	1.00
504_T	528_M	1.628	1.00
118_K	121_Q	1.626	1.00
377_V	420_A	1.618	1.00
510_A	514_H	1.618	1.00
336_A	340_H	1.604	1.00
363_Q	506_A	1.587	1.00
412_C	416_G	1.582	1.00
341_M	345_W	1.577	1.00
208_I	230_A	1.573	1.00
135_S	138_S	1.573	1.00
8_Q	39_H	1.570	1.00
219_R	223_E	1.569	1.00
368_L	432_V	1.569	1.00
381_D	433_C	1.567	1.00
192_Q	195_T	1.553	1.00
494_E	499_K	1.550	1.00
127_A	158_V	1.549	1.00
511_P	515_E	1.545	1.00
12_E	15_E	1.540	1.00
371_A	510_A	1.527	1.00
24_G	46_F	1.518	1.00
131_R	159_L	1.497	1.00
66_T	423_S	1.496	1.00
274_L	293_L	1.493	1.00
381_D	437_G	1.489	1.00
34_I	46_F	1.485	1.00
229_A	248_H	1.480	1.00
300_I	311_V	1.475	1.00
136_A	168_E	1.462	1.00
402_I	420_A	1.461	1.00
128_V	155_G	1.457	1.00
363_Q	367_R	1.457	1.00
421_S	453_L	1.456	1.00
200_I	270_L	1.455	1.00
490_A	502_K	1.454	1.00
335_N	339_E	1.446	1.00
13_L	144_N	1.446	1.00
400_D	427_R	1.444	1.00
10_M	161_V	1.435	1.00
511_P	514_H	1.431	1.00
203_A	206_P	1.430	1.00
458_V	525_V	1.424	1.00
197_A	324_Y	1.416	1.00
367_R	371_A	1.415	1.00
270_L	291_I	1.405	1.00
54_V	444_D	1.385	1.00
331_R	335_N	1.384	1.00
448_A	455_I	1.383	1.00
10_M	143_L	1.377	1.00
376_A	428_Q	1.375	1.00
232_I	242_V	1.372	1.00
69_I	147_I	1.369	1.00
448_A	498_A	1.367	1.00
289_P	307_T	1.360	1.00
458_V	513_F	1.356	1.00
100_I	161_V	1.353	1.00
445_L	498_A	1.353	1.00
267_E	336_A	1.353	1.00
106_S	164_D	1.352	1.00
422_L	453_L	1.352	1.00
49_T	58_A	1.348	1.00
364_V	527_V	1.346	1.00
373_A	428_Q	1.342	1.00
21_H	422_L	1.337	1.00
197_A	321_L	1.332	1.00
17_W	147_I	1.330	1.00
430_I	517_L	1.329	1.00
442_M	492_F	1.322	1.00
374_D	396_N	1.320	1.00
83_L	99_A	1.318	1.00
372_A	430_I	1.317	1.00
458_V	527_V	1.315	1.00
490_A	494_E	1.314	1.00
223_E	322_T	1.314	1.00
45_K	451_Y	1.311	1.00
339_E	343_H	1.310	1.00
315_A	319_R	1.302	1.00
188_P	317_G	1.288	1.00
421_S	428_Q	1.287	1.00
98_L	150_A	1.284	1.00
17_W	144_N	1.281	1.00
56_A	83_L	1.277	1.00
377_V	424_E	1.276	1.00
428_Q	517_L	1.273	1.00
274_L	318_L	1.272	1.00
456_T	516_A	1.271	1.00
224_F	228_A	1.267	1.00
338_T	341_M	1.265	1.00
203_A	270_L	1.264	1.00
418_I	448_A	1.262	1.00
87_L	97_V	1.261	1.00
492_F	496_C	1.261	1.00
193_L	324_Y	1.260	1.00
207_I	268_C	1.258	1.00
133_V	139_L	1.257	1.00
301_G	306_V	1.256	1.00
431_A	457_V	1.244	1.00
80_A	101_A	1.243	1.00
138_S	141_D	1.235	1.00
463_E	486_N	1.226	1.00
337_C	341_M	1.225	1.00
338_T	342_Q	1.224	1.00
194_V	198_Q	1.220	1.00
224_F	322_T	1.213	1.00
23_Y	62_E	1.211	1.00
454_P	521_Q	1.210	1.00
15_E	41_R	1.207	1.00
221_L	318_L	1.206	1.00
454_P	520_D	1.202	1.00
47_I	422_L	1.199	1.00
359_L	527_V	1.199	1.00
143_L	159_L	1.198	1.00
222_L	243_P	1.198	1.00
141_D	145_Q	1.197	1.00
491_A	495_S	1.195	1.00
374_D	397_A	1.190	1.00
7_G	36_E	1.190	1.00
22_V	37_L	1.190	1.00
224_F	318_L	1.189	1.00
320_E	323_E	1.188	1.00
223_E	226_D	1.178	1.00
62_E	423_S	1.177	1.00
187_E	320_E	1.173	1.00
313_D	316_L	1.172	1.00
377_V	429_A	1.170	1.00
214_M	221_L	1.170	1.00
493_A	524_V	1.169	1.00
234_V	249_F	1.168	1.00
195_T	199_Y	1.167	1.00
509_L	527_V	1.167	1.00
263_E	267_E	1.165	1.00
13_L	143_L	1.164	1.00
359_L	364_V	1.163	1.00
220_E	223_E	1.160	1.00
316_L	319_R	1.154	1.00
208_I	224_F	1.153	1.00
63_A	96_P	1.152	1.00
60_A	89_D	1.145	1.00
410_M	440_M	1.141	1.00
9_A	170_I	1.139	1.00
162_S	165_L	1.139	1.00
201_N	326_E	1.138	1.00
498_A	524_V	1.136	1.00
5_T	169_K	1.135	1.00
190_K	324_Y	1.135	1.00
131_R	145_Q	1.135	1.00
133_V	142_L	1.131	1.00
15_E	42_N	1.131	1.00
499_K	519_S	1.130	1.00
5_T	8_Q	1.130	1.00
20_D	45_K	1.129	1.00
131_R	142_L	1.127	1.00
197_A	201_N	1.125	1.00
512_A	525_V	1.123	1.00
210_A	214_M	1.122	1.00
342_Q	346_N	1.118	1.00
84_L	122_M	1.117	1.00
88_Y	407_L	1.116	1.00
493_A	498_A	1.113	1.00
222_L	242_V	1.112	1.00
205_K	267_E	1.112	1.00
19_V	71_V	1.112	1.00
107_G	164_D	1.109	1.00
106_S	168_E	1.107	1.00
493_A	500_G	1.105	1.00
201_N	328_K	1.105	1.00
6_A	139_L	1.101	1.00
84_L	126_V	1.095	1.00
515_E	518_H	1.093	1.00
65_L	420_A	1.091	1.00
446_P	450_K	1.090	1.00
149_T	157_A	1.089	1.00
259_K	263_E	1.089	1.00
220_E	322_T	1.080	1.00
206_P	269_D	1.079	1.00
60_A	95_A	1.079	1.00
21_H	47_I	1.078	1.00
242_V	246_H	1.075	1.00
10_M	100_I	1.070	1.00
233_V	250_L	1.062	1.00
239_K	244_D	1.062	1.00
378_L	393_F	1.059	1.00
81_V	122_M	1.059	1.00
122_M	126_V	1.058	1.00
219_R	222_L	1.058	1.00
500_G	524_V	1.056	1.00
225_A	242_V	1.054	1.00
91_K	156_V	1.054	1.00
54_V	441_V	1.049	1.00
339_E	342_Q	1.049	1.00
223_E	319_R	1.046	1.00
509_L	513_F	1.044	1.00
222_L	246_H	1.041	1.00
501_I	525_V	1.038	1.00
463_E	528_M	1.038	1.00
72_C	83_L	1.035	1.00
127_A	130_N	1.033	1.00
250_L	264_A	1.033	1.00
421_S	429_A	1.030	1.00
4_K	169_K	1.028	1.00
207_I	233_V	1.027	1.00
428_Q	456_T	1.027	1.00
56_A	72_C	1.025	1.00
456_T	523_V	1.021	1.00
226_D	248_H	1.019	1.00
375_D	427_R	1.018	1.00
225_A	248_H	1.015	1.00
202_N	289_P	1.013	1.00
372_A	378_L	1.013	1.00
9_A	140_P	1.011	1.00
30_I	33_F	1.009	1.00
197_A	325_I	1.009	1.00
208_I	221_L	1.008	1.00
109_V	132_E	1.008	1.00
306_V	309_G	1.006	1.00
421_S	425_P	1.005	1.00
503_V	508_E	1.003	1.00
196_C	308_A	1.002	1.00
129_F	149_T	1.002	1.00
61_A	65_L	1.002	1.00
316_L	320_E	0.997	1.00
414_L	438_F	0.994	1.00
196_C	310_L	0.994	1.00
10_M	33_F	0.991	1.00
47_I	451_Y	0.991	1.00
227_K	327_R	0.990	1.00
285_P	288_T	0.986	1.00
519_S	523_V	0.986	1.00
22_V	71_V	0.985	1.00
187_E	316_L	0.982	1.00
273_M	278_F	0.980	1.00
360_K	533_P	0.978	1.00
203_A	269_D	0.977	1.00
188_P	320_E	0.977	1.00
334_L	338_T	0.975	1.00
340_H	344_W	0.969	1.00
446_P	496_C	0.968	1.00
151_Y	154_K	0.966	1.00
379_S	429_A	0.966	1.00
503_V	509_L	0.964	1.00
438_F	459_I	0.960	1.00
218_K	222_L	0.959	1.00
397_A	400_D	0.954	1.00
459_I	489_Y	0.952	1.00
198_Q	201_N	0.951	1.00
103_Q	160_S	0.949	1.00
413_G	431_A	0.945	1.00
490_A	526_D	0.945	1.00
191_E	194_V	0.944	1.00
87_L	123_F	0.943	1.00
379_S	431_A	0.942	1.00
365_V	432_V	0.941	1.00
508_E	512_A	0.939	1.00
421_S	426_E	0.935	1.00
516_A	523_V	0.934	1.00
369_Q	393_F	0.934	1.00
201_N	325_I	0.933	1.00
442_M	496_C	0.931	1.00
130_N	158_V	0.931	1.00
190_K	194_V	0.926	1.00
120_E	130_N	0.925	1.00
74_S	99_A	0.925	1.00
363_Q	509_L	0.923	1.00
469_E	483_K	0.922	1.00
68_K	151_Y	0.922	1.00
72_C	99_A	0.921	1.00
220_E	318_L	0.921	1.00
498_A	522_P	0.917	1.00
335_N	338_T	0.917	1.00
33_F	161_V	0.915	1.00
80_A	123_F	0.914	1.00
202_N	270_L	0.913	1.00
445_L	524_V	0.911	1.00
337_C	340_H	0.910	1.00
452_K	520_D	0.909	1.00
8_Q	12_E	0.909	1.00
145_Q	149_T	0.907	1.00
223_E	326_E	0.906	1.00
512_A	516_A	0.903	1.00
56_A	97_V	0.901	1.00
460_L	529_I	0.900	1.00
445_L	457_V	0.899	1.00
207_I	271_L	0.898	1.00
456_T	517_L	0.897	1.00
6_A	136_A	0.891	1.00
129_F	142_L	0.890	1.00
196_C	270_L	0.889	1.00
64_K	95_A	0.886	1.00
37_L	44_L	0.884	1.00
13_L	17_W	0.878	1.00
81_V	88_Y	0.873	1.00
121_Q	125_D	0.868	1.00
389_M	432_V	0.867	1.00
448_A	457_V	0.866	1.00
421_S	521_Q	0.866	1.00
364_V	460_L	0.864	1.00
438_F	524_V	0.864	1.00
376_A	430_I	0.863	1.00
300_I	309_G	0.860	1.00
207_I	265_M	0.859	1.00
512_A	515_E	0.855	1.00
253_L	265_M	0.855	1.00
439_S	442_M	0.852	1.00
371_A	513_F	0.850	1.00
198_Q	328_K	0.848	1.00
129_F	146_A	0.847	1.00
456_T	525_V	0.847	1.00
297_P	311_V	0.845	1.00
336_A	339_E	0.843	1.00
61_A	416_G	0.843	1.00
65_L	402_I	0.842	1.00
120_E	132_E	0.841	1.00
448_A	522_P	0.840	1.00
199_Y	291_I	0.840	1.00
375_D	397_A	0.839	1.00
85_N	409_T	0.838	1.00
94_G	153_K	0.838	1.00
419_A	423_S	0.837	1.00
463_E	531_N	0.833	1.00
432_V	460_L	0.832	1.00
150_A	157_A	0.830	1.00
84_L	123_F	0.830	1.00
205_K	269_D	0.830	1.00
310_L	317_G	0.829	1.00
224_F	325_I	0.828	1.00
13_L	16_Q	0.827	1.00
365_V	460_L	0.824	1.00
58_A	448_A	0.824	1.00
21_H	62_E	0.824	1.00
332_R	335_N	0.822	1.00
188_P	193_L	0.821	1.00
367_R	509_L	0.820	1.00
494_E	500_G	0.820	1.00
35_E	38_R	0.818	1.00
208_I	274_L	0.816	1.00
148_R	152_S	0.816	1.00
244_D	249_F	0.816	1.00
436_G	465_L	0.815	1.00
98_L	151_Y	0.815	1.00
32_E	167_A	0.815	1.00
161_V	166_F	0.809	1.00
455_I	522_P	0.809	1.00
217_A	220_E	0.808	1.00
371_A	517_L	0.808	1.00
228_A	325_I	0.806	1.00
196_C	199_Y	0.806	1.00
193_L	320_E	0.805	1.00
210_A	232_I	0.801	1.00
216_K	399_Q	0.800	1.00
245_K	374_D	0.798	1.00
71_V	98_L	0.797	1.00
210_A	234_V	0.797	1.00
515_E	519_S	0.794	1.00
488_D	502_K	0.792	1.00
359_L	506_A	0.789	1.00
320_E	324_Y	0.789	1.00
430_I	458_V	0.789	1.00
57_L	409_T	0.784	1.00
293_L	310_L	0.783	1.00
195_T	308_A	0.782	1.00
418_I	453_L	0.781	1.00
129_F	145_Q	0.781	1.00
196_C	317_G	0.781	1.00
214_M	241_V	0.778	1.00
450_K	485_Q	0.777	1.00
14_L	71_V	0.777	1.00
337_C	345_W	0.776	1.00
341_M	344_W	0.775	1.00
330_D	334_L	0.774	1.00
129_F	157_A	0.774	1.00
478_I	481_V	0.773	1.00
65_L	423_S	0.772	1.00
128_V	157_A	0.769	1.00
461_N	528_M	0.767	1.00
39_H	42_N	0.765	1.00
456_T	520_D	0.765	1.00
4_K	9_A	0.763	1.00
417_A	455_I	0.762	1.00
20_D	62_E	0.760	1.00
5_T	36_E	0.760	1.00
365_V	393_F	0.758	1.00
507_E	511_P	0.753	1.00
254_G	257_G	0.751	1.00
73_L	100_I	0.750	1.00
488_D	494_E	0.749	1.00
88_Y	126_V	0.748	1.00
242_V	249_F	0.748	1.00
62_E	68_K	0.747	1.00
282_D	286_D	0.743	1.00
201_N	323_E	0.742	1.00
136_A	140_P	0.742	1.00
369_Q	396_N	0.741	1.00
449_V	522_P	0.739	1.00
17_W	151_Y	0.739	1.00
26_P	48_Q	0.739	1.00
15_E	20_D	0.735	1.00
201_N	324_Y	0.735	1.00
36_E	39_H	0.734	1.00
23_Y	58_A	0.734	1.00
414_L	457_V	0.734	1.00
380_V	401_F	0.733	1.00
22_V	73_L	0.731	1.00
385_V	437_G	0.730	1.00
380_V	389_M	0.730	1.00
215_K	399_Q	0.729	1.00
132_E	160_S	0.727	1.00
49_T	54_V	0.726	1.00
272_I	293_L	0.725	1.00
469_E	473_Q	0.724	1.00
20_D	43_Q	0.722	1.00
270_L	289_P	0.721	1.00
188_P	316_L	0.721	1.00
185_N	313_D	0.720	1.00
377_V	427_R	0.719	1.00
236_L	390_A	0.718	1.00
206_P	230_A	0.718	1.00
63_A	95_A	0.717	1.00
243_P	396_N	0.716	1.00
430_I	456_T	0.716	1.00
145_Q	148_R	0.715	1.00
19_V	147_I	0.714	1.00
380_V	403_V	0.714	1.00
212_Q	237_P	0.711	1.00
428_Q	454_P	0.707	1.00
333_F	336_A	0.707	1.00
25_I	83_L	0.705	1.00
128_V	149_T	0.703	1.00
439_S	487_V	0.702	1.00
217_A	315_A	0.702	1.00
483_K	531_N	0.701	1.00
449_V	497_G	0.701	1.00
30_I	73_L	0.700	1.00
206_P	270_L	0.699	1.00
175_V	178_S	0.696	1.00
282_D	285_P	0.696	1.00
342_Q	345_W	0.696	1.00
142_L	145_Q	0.694	1.00
414_L	444_D	0.694	1.00
372_A	376_A	0.693	1.00
344_W	348_I	0.690	1.00
149_T	153_K	0.690	1.00
432_V	458_V	0.688	1.00
120_E	124_E	0.687	1.00
30_I	34_I	0.687	1.00
457_V	498_A	0.685	1.00
63_A	97_V	0.684	0.99
74_S	101_A	0.684	0.99
53_E	82_H	0.683	0.99
136_A	170_I	0.682	0.99
81_V	84_L	0.681	0.99
500_G	526_D	0.680	0.99
204_K	269_D	0.679	0.99
101_A	160_S	0.679	0.99
33_F	166_F	0.678	0.99
234_V	244_D	0.677	0.99
38_R	479_D	0.677	0.99
381_D	413_G	0.676	0.99
106_S	134_H	0.675	0.99
128_V	152_S	0.675	0.99
317_G	320_E	0.674	0.99
62_E	66_T	0.672	0.99
243_P	246_H	0.672	0.99
319_R	323_E	0.671	0.99
319_R	322_T	0.671	0.99
33_F	73_L	0.669	0.99
87_L	126_V	0.669	0.99
439_S	489_Y	0.667	0.99
123_F	158_V	0.667	0.99
379_S	420_A	0.663	0.99
314_S	319_R	0.663	0.99
333_F	341_M	0.663	0.99
74_S	80_A	0.662	0.99
209_L	273_M	0.662	0.99
464_N	469_E	0.661	0.99
431_A	437_G	0.660	0.99
229_A	247_P	0.657	0.99
379_S	402_I	0.655	0.99
422_L	451_Y	0.655	0.99
187_E	190_K	0.654	0.99
503_V	525_V	0.653	0.99
140_P	144_N	0.653	0.99
192_Q	196_C	0.653	0.99
449_V	485_Q	0.653	0.99
90_A	97_V	0.651	0.99
322_T	326_E	0.649	0.99
324_Y	328_K	0.648	0.99
95_A	412_C	0.648	0.99
359_L	505_K	0.648	0.99
91_K	128_V	0.648	0.99
364_V	458_V	0.648	0.99
330_D	333_F	0.645	0.99
136_A	165_L	0.645	0.99
418_I	447_T	0.644	0.99
56_A	99_A	0.644	0.99
208_I	232_I	0.642	0.99
458_V	509_L	0.640	0.99
21_H	68_K	0.640	0.99
448_A	453_L	0.638	0.99
438_F	489_Y	0.637	0.99
332_R	336_A	0.637	0.99
75_I	115_Q	0.635	0.99
340_H	343_H	0.635	0.99
50_R	450_K	0.635	0.99
263_E	266_E	0.634	0.99
8_Q	41_R	0.632	0.99
487_V	495_S	0.631	0.99
218_K	398_N	0.631	0.99
343_H	346_N	0.630	0.99
32_E	166_F	0.629	0.99
333_F	345_W	0.629	0.99
16_Q	176_Y	0.627	0.99
262_Y	266_E	0.626	0.99
323_E	326_E	0.625	0.99
346_N	349_E	0.625	0.99
402_I	412_C	0.624	0.99
417_A	429_A	0.624	0.99
81_V	117_I	0.624	0.99
501_I	519_S	0.622	0.99
520_D	523_V	0.622	0.99
454_P	522_P	0.622	0.99
22_V	44_L	0.621	0.99
498_A	521_Q	0.620	0.99
133_V	162_S	0.620	0.99
209_L	235_T	0.620	0.99
227_K	325_I	0.617	0.99
512_A	523_V	0.617	0.99
229_A	334_L	0.616	0.99
199_Y	202_N	0.616	0.99
147_I	151_Y	0.615	0.99
82_H	85_N	0.615	0.99
4_K	8_Q	0.613	0.99
30_I	102_G	0.613	0.99
368_L	458_V	0.613	0.99
433_C	457_V	0.613	0.99
204_K	330_D	0.611	0.99
414_L	433_C	0.610	0.99
138_S	142_L	0.610	0.99
415_P	444_D	0.609	0.99
92_A	407_L	0.609	0.99
284_L	288_T	0.608	0.99
292_Q	306_V	0.608	0.99
414_L	448_A	0.608	0.99
317_G	321_L	0.607	0.99
505_K	511_P	0.604	0.99
283_Y	286_D	0.602	0.99
57_L	89_D	0.602	0.99
220_E	224_F	0.602	0.99
106_S	162_S	0.601	0.99
128_V	153_K	0.601	0.99
345_W	394_K	0.600	0.99
221_L	225_A	0.599	0.99
45_K	425_P	0.598	0.99
192_Q	310_L	0.598	0.99
209_L	276_T	0.597	0.99
488_D	526_D	0.596	0.99
20_D	66_T	0.596	0.99
100_I	143_L	0.595	0.99
228_A	248_H	0.594	0.99
294_D	299_K	0.593	0.99
364_V	509_L	0.590	0.99
101_A	119_L	0.589	0.98
6_A	9_A	0.589	0.98
363_Q	510_A	0.588	0.98
15_E	44_L	0.588	0.98
62_E	70_G	0.587	0.98
225_A	228_A	0.586	0.98
223_E	323_E	0.585	0.98
11_T	42_N	0.585	0.98
337_C	349_E	0.584	0.98
209_L	271_L	0.583	0.98
358_P	530_G	0.583	0.98
513_F	517_L	0.580	0.98
146_A	159_L	0.580	0.98
438_F	457_V	0.579	0.98
273_M	290_A	0.578	0.98
420_A	429_A	0.578	0.98
376_A	427_R	0.578	0.98
300_I	306_V	0.577	0.98
45_K	422_L	0.577	0.98
239_K	395_M	0.577	0.98
193_L	310_L	0.576	0.98
103_Q	109_V	0.575	0.98
452_K	521_Q	0.574	0.98
164_D	168_E	0.574	0.98
193_L	321_L	0.574	0.98
380_V	413_G	0.574	0.98
357_T	506_A	0.573	0.98
13_L	140_P	0.573	0.98
69_I	150_A	0.573	0.98
487_V	492_F	0.573	0.98
149_T	152_S	0.573	0.98
58_A	422_L	0.573	0.98
379_S	413_G	0.571	0.98
217_A	314_S	0.570	0.98
98_L	157_A	0.570	0.98
200_I	228_A	0.570	0.98
433_C	441_V	0.569	0.98
106_S	135_S	0.566	0.98
71_V	147_I	0.565	0.98
240_G	244_D	0.564	0.98
205_K	333_F	0.563	0.98
442_M	495_S	0.562	0.98
457_V	524_V	0.562	0.98
65_L	377_V	0.560	0.98
247_P	338_T	0.559	0.98
349_E	366_A	0.559	0.98
61_A	419_A	0.558	0.98
234_V	239_K	0.558	0.98
357_T	505_K	0.558	0.98
372_A	393_F	0.558	0.98
501_I	511_P	0.557	0.98
213_G	294_D	0.556	0.98
51_H	82_H	0.555	0.98
344_W	347_E	0.553	0.98
204_K	336_A	0.553	0.98
244_D	394_K	0.552	0.98
96_P	150_A	0.552	0.98
131_R	157_A	0.551	0.98
153_K	296_D	0.550	0.98
365_V	369_Q	0.549	0.98
35_E	479_D	0.549	0.98
222_L	225_A	0.548	0.98
324_Y	327_R	0.548	0.98
71_V	100_I	0.548	0.98
188_P	312_C	0.547	0.98
362_Q	533_P	0.546	0.98
190_K	323_E	0.546	0.98
185_N	316_L	0.546	0.98
106_S	165_L	0.545	0.98
140_P	143_L	0.545	0.98
60_A	416_G	0.545	0.98
25_I	465_L	0.545	0.98
204_K	332_R	0.545	0.98
237_P	405_S	0.544	0.97
11_T	41_R	0.544	0.97
192_Q	308_A	0.544	0.97
447_T	453_L	0.540	0.97
385_V	460_L	0.540	0.97
98_L	159_L	0.539	0.97
389_M	401_F	0.539	0.97
373_A	517_L	0.537	0.97
13_L	147_I	0.537	0.97
23_Y	422_L	0.537	0.97
189_K	316_L	0.536	0.97
136_A	139_L	0.536	0.97
449_V	452_K	0.536	0.97
100_I	159_L	0.536	0.97
446_P	487_V	0.536	0.97
469_E	531_N	0.535	0.97
299_K	302_K	0.535	0.97
6_A	168_E	0.533	0.97
506_A	510_A	0.532	0.97
219_R	226_D	0.532	0.97
379_S	416_G	0.531	0.97
266_E	286_D	0.531	0.97
103_Q	132_E	0.531	0.97
55_A	72_C	0.531	0.97
289_P	308_A	0.530	0.97
16_Q	172_R	0.530	0.97
459_I	526_D	0.529	0.97
250_L	261_A	0.528	0.97
88_Y	117_I	0.528	0.97
185_N	189_K	0.528	0.97
372_A	517_L	0.527	0.97
56_A	87_L	0.527	0.97
456_T	521_Q	0.527	0.97
377_V	402_I	0.527	0.97
397_A	427_R	0.525	0.97
83_L	101_A	0.524	0.97
201_N	204_K	0.524	0.97
468_I	472_Q	0.524	0.97
25_I	49_T	0.523	0.97
18_G	68_K	0.523	0.97
439_S	443_Q	0.522	0.97
242_V	247_P	0.522	0.97
229_A	327_R	0.521	0.97
207_I	264_A	0.521	0.97
503_V	511_P	0.520	0.97
11_T	37_L	0.520	0.97
64_K	93_D	0.520	0.97
50_R	446_P	0.518	0.97
63_A	70_G	0.518	0.97
444_D	447_T	0.517	0.97
110_G	116_E	0.515	0.97
494_E	501_I	0.515	0.97
240_G	400_D	0.513	0.96
234_V	241_V	0.513	0.96
503_V	527_V	0.512	0.96
114_F	408_A	0.512	0.96
375_D	428_Q	0.512	0.96
456_T	519_S	0.512	0.96
28_D	75_I	0.511	0.96
499_K	520_D	0.511	0.96
433_C	437_G	0.510	0.96
365_V	389_M	0.510	0.96
148_R	151_Y	0.510	0.96
124_E	130_N	0.509	0.96
119_L	158_V	0.508	0.96
47_I	447_T	0.508	0.96
14_L	100_I	0.507	0.96
89_D	93_D	0.506	0.96
141_D	144_N	0.505	0.96
63_A	69_I	0.504	0.96
27_G	75_I	0.502	0.96
487_V	496_C	0.502	0.96
337_C	344_W	0.502	0.96
174_P	178_S	0.502	0.96
222_L	248_H	0.501	0.96
83_L	86_G	0.501	0.96
212_Q	277_S	0.501	0.96
333_F	344_W	0.501	0.96
215_K	241_V	0.501	0.96
91_K	127_A	0.500	0.96
514_H	517_L	0.500	0.96
449_V	521_Q	0.500	0.96

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3eyaA	5	0.9181	100	0.189	Contact Map
1v5eA	4	0.993	100	0.201	Contact Map
1ozhA	4	0.939	100	0.202	Contact Map
1t9bA	2	0.9895	100	0.203	Contact Map
1ybhA	4	0.9564	100	0.204	Contact Map
4kgdA	4	0.9913	100	0.205	Contact Map
2panA	3	0.9826	100	0.208	Contact Map
4rjjA	5	0.946	100	0.209	Contact Map
2pgnA	4	0.9808	100	0.211	Contact Map
2ihtA	4	0.9251	100	0.217	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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