GREMLIN Database
MTLR - Transcriptional regulator MtlR
UniProt: P96574 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 694 (626)
Sequences: 2180 (1889)
Seq/√Len: 75.5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
6_R40_E5.6061.00
154_E237_R4.5581.00
91_R125_D4.3471.00
365_K390_D4.0501.00
332_N406_I4.0111.00
414_K441_E3.8211.00
32_V37_I3.7501.00
672_G675_E3.7001.00
138_L152_G3.6091.00
214_K265_E3.5461.00
41_L45_K3.5431.00
117_V122_V3.4911.00
548_T616_S3.4171.00
361_K394_A3.4111.00
98_S114_D3.3031.00
137_G156_A3.1931.00
615_L618_P3.1591.00
117_V125_D3.0121.00
154_E158_R3.0121.00
416_L446_S2.8821.00
632_T668_F2.8751.00
557_L576_A2.8081.00
136_F163_N2.7521.00
158_R282_E2.6931.00
553_S583_E2.6641.00
322_S328_D2.6431.00
419_C422_G2.5881.00
540_H674_Q2.5621.00
138_L150_L2.5601.00
541_F566_D2.5011.00
551_D554_M2.4991.00
130_E142_R2.4791.00
467_P477_M2.4311.00
315_K336_Y2.3921.00
158_R237_R2.3871.00
605_I638_M2.3551.00
430_A434_K2.3531.00
543_L673_G2.3311.00
117_V121_T2.3221.00
417_V433_L2.2801.00
332_N403_A2.2761.00
36_T40_E2.2731.00
559_L613_F2.2371.00
13_H26_L2.2361.00
381_K387_S2.2241.00
429_L465_T2.1951.00
153_P156_A2.1801.00
549_N558_E2.1521.00
570_R606_V2.1501.00
415_A463_V2.1351.00
32_V40_E2.1321.00
427_K430_A2.1131.00
555_L613_F2.0941.00
329_L400_F2.0821.00
230_H289_H2.0741.00
13_H21_I2.0581.00
45_K57_K2.0581.00
559_L636_V2.0051.00
359_P391_D1.9971.00
365_K372_Y1.9791.00
556_L576_A1.9731.00
564_K569_I1.9701.00
26_L37_I1.9691.00
568_L607_L1.9601.00
560_F576_A1.9471.00
415_A440_I1.9211.00
255_M280_E1.9161.00
618_P632_T1.9131.00
561_Q565_K1.9091.00
56_D66_V1.8991.00
582_R588_L1.8701.00
45_K55_L1.8621.00
664_S668_F1.8551.00
84_H90_E1.8491.00
376_E390_D1.8451.00
34_T38_H1.8431.00
375_I397_V1.8411.00
314_T343_L1.8381.00
574_K578_C1.8331.00
210_Q269_E1.8291.00
419_C426_S1.8111.00
596_A631_M1.8051.00
578_C582_R1.7631.00
546_L614_D1.7601.00
271_E277_T1.7581.00
479_S486_D1.7541.00
143_K146_F1.7541.00
548_T617_T1.7401.00
132_W160_I1.7381.00
321_I374_A1.7341.00
545_Q614_D1.7271.00
358_N394_A1.7251.00
20_Y64_K1.7251.00
560_F636_V1.7211.00
555_L634_I1.7091.00
6_R36_T1.7061.00
324_K377_E1.6941.00
141_I151_I1.6881.00
552_H621_V1.6791.00
317_L400_F1.6791.00
152_G157_K1.6661.00
486_D489_Q1.6631.00
358_N391_D1.6581.00
608_P640_P1.6541.00
568_L609_F1.6531.00
379_V396_I1.6431.00
346_A350_I1.6321.00
322_S332_N1.6311.00
129_L140_L1.6231.00
582_R589_G1.6191.00
547_K613_F1.6161.00
594_N632_T1.6151.00
92_K129_L1.6051.00
96_L129_L1.6000.99
620_E623_G1.5940.99
7_E43_S1.5910.99
13_H29_L1.5910.99
162_G230_H1.5630.99
542_T566_D1.5550.99
357_Y391_D1.5540.99
371_L397_V1.5510.99
588_L621_V1.5320.99
610_F635_L1.5250.99
570_R573_E1.5220.99
226_A289_H1.5080.99
559_L611_K1.4990.99
208_L228_V1.4950.99
437_L491_K1.4910.99
349_R392_E1.4870.99
109_Y119_N1.4800.99
58_Q61_K1.4790.99
463_V478_V1.4750.99
231_L286_I1.4680.99
264_L283_V1.4650.99
490_V494_I1.4630.99
4_T7_E1.4630.99
339_L396_I1.4620.99
482_L490_V1.4560.99
447_S450_E1.4560.99
59_P62_G1.4560.99
553_S557_L1.4530.99
13_H30_M1.4530.99
321_I400_F1.4520.99
257_A260_Y1.4480.99
41_L63_L1.4470.99
321_I375_I1.4450.99
549_N555_L1.4430.99
335_L339_L1.4410.99
318_I336_Y1.4330.99
215_I265_E1.4300.99
325_I374_A1.4300.99
544_A562_Q1.4280.99
567_G606_V1.4220.99
10_L26_L1.4180.99
226_A230_H1.4170.99
413_V494_I1.4150.99
87_S90_E1.4080.99
412_K441_E1.4060.99
334_S406_I1.4040.99
342_H399_H1.4030.99
575_A579_L1.4020.99
576_A580_A1.4000.99
335_L403_A1.3960.99
671_E675_E1.3930.99
53_L67_G1.3780.98
27_A34_T1.3720.98
35_R401_G1.3700.98
211_L266_I1.3670.98
193_F196_V1.3660.98
543_L614_D1.3620.98
574_K580_A1.3600.98
552_H622_D1.3530.98
335_L406_I1.3520.98
419_C466_V1.3520.98
14_L65_A1.3500.98
20_Y62_G1.3480.98
623_G629_L1.3480.98
547_K616_S1.3430.98
329_L403_A1.3430.98
138_L157_K1.3350.98
96_L133_I1.3330.98
154_E282_E1.3300.98
24_T28_E1.3130.98
546_L616_S1.3100.98
107_K147_G1.3090.98
316_R383_F1.3050.98
11_L44_I1.3020.98
91_R121_T1.2980.98
633_R668_F1.2960.98
95_I129_L1.2870.98
583_E588_L1.2850.98
563_L569_I1.2840.98
463_V476_I1.2770.97
259_E287_T1.2660.97
260_Y287_T1.2650.97
358_N395_F1.2650.97
569_I575_A1.2650.97
144_R147_G1.2650.97
162_G233_Y1.2620.97
538_L612_M1.2610.97
27_A37_I1.2570.97
105_P149_Q1.2560.97
608_P639_A1.2530.97
88_A128_E1.2520.97
279_P282_E1.2450.97
670_E679_R1.2420.97
415_A494_I1.2410.97
579_L636_V1.2390.97
7_E40_E1.2380.97
56_D64_K1.2360.97
444_D459_Y1.2360.97
464_S477_M1.2340.97
139_T151_I1.2320.97
420_S466_V1.2300.97
459_Y473_I1.2290.97
23_V63_L1.2210.97
24_T34_T1.2190.97
371_L375_I1.2150.97
92_K128_E1.2150.97
399_H402_S1.2110.97
361_K390_D1.2110.97
650_I654_I1.2090.96
581_E584_K1.2090.96
346_A349_R1.2060.96
371_L401_G1.2020.96
342_H599_H1.1990.96
416_L459_Y1.1970.96
620_E630_R1.1890.96
116_Q621_V1.1880.96
107_K110_T1.1880.96
111_L122_V1.1840.96
32_V36_T1.1830.96
422_G425_S1.1820.96
33_S36_T1.1800.96
238_I282_E1.1770.96
263_A283_V1.1740.96
615_L632_T1.1720.96
554_M557_L1.1720.96
264_L280_E1.1700.96
141_I149_Q1.1680.96
92_K125_D1.1650.96
3_M7_E1.1640.96
88_A125_D1.1600.96
203_K273_A1.1520.95
575_A578_C1.1520.95
673_G676_L1.1480.95
4_T43_S1.1470.95
673_G677_Y1.1440.95
418_V468_I1.1400.95
27_A32_V1.1380.95
13_H17_Q1.1350.95
614_D633_R1.1330.95
574_K577_V1.1330.95
212_K219_L1.1320.95
569_I638_M1.1280.95
35_R39_R1.1260.95
220_S294_N1.1240.95
94_L115_L1.1230.95
552_H582_R1.1230.95
292_S345_P1.1180.95
402_S406_I1.1160.94
550_P554_M1.1150.94
612_M676_L1.1150.94
589_G621_V1.1140.94
405_E432_R1.1130.94
254_L260_Y1.1120.94
578_C589_G1.1110.94
600_L638_M1.1090.94
560_F564_K1.1060.94
238_I278_I1.1050.94
259_E291_R1.1050.94
263_A287_T1.1040.94
422_G426_S1.1040.94
575_A580_A1.0980.94
310_T314_T1.0880.94
129_L133_I1.0850.94
71_G74_K1.0800.93
538_L542_T1.0790.93
41_L55_L1.0780.93
621_V634_I1.0740.93
542_T568_L1.0740.93
204_M232_T1.0740.93
338_G406_I1.0740.93
421_S425_S1.0730.93
476_I486_D1.0680.93
610_F650_I1.0670.93
122_V129_L1.0640.93
436_E491_K1.0620.93
574_K582_R1.0600.93
317_L375_I1.0570.93
122_V125_D1.0530.93
403_A406_I1.0520.93
107_K146_F1.0500.92
332_N405_E1.0480.92
647_G651_L1.0470.92
414_K458_A1.0420.92
544_A558_E1.0370.92
556_L636_V1.0350.92
493_Y497_K1.0340.92
236_E240_L1.0330.92
546_L615_L1.0320.92
142_R148_I1.0310.92
556_L560_F1.0300.92
558_E562_Q1.0290.92
464_S475_Y1.0280.92
112_A122_V1.0270.92
596_A621_V1.0260.92
287_T291_R1.0250.92
263_A290_L1.0230.91
325_I329_L1.0220.91
375_I379_V1.0220.91
30_M37_I1.0220.91
285_Y359_P1.0160.91
237_R282_E1.0150.91
317_L378_G1.0140.91
263_A266_I1.0130.91
57_K63_L1.0090.91
121_T125_D1.0070.91
293_A346_A1.0060.91
108_L119_N1.0050.91
588_L598_Y1.0010.91
432_R481_L0.9980.90
436_E487_A0.9970.90
379_V388_F0.9930.90
419_C424_G0.9910.90
260_Y283_V0.9900.90
478_V482_L0.9890.90
621_V631_M0.9880.90
372_Y376_E0.9860.90
670_E675_E0.9860.90
318_I335_L0.9860.90
205_E225_I0.9840.90
320_F323_D0.9810.90
36_T39_R0.9790.90
391_D394_A0.9770.89
267_A271_E0.9760.89
543_L676_L0.9750.89
363_Q367_D0.9700.89
335_L378_G0.9700.89
577_V581_E0.9650.89
437_L487_A0.9640.89
314_T340_I0.9640.89
549_N615_L0.9620.89
399_H424_G0.9610.89
96_L164_L0.9590.89
207_I211_L0.9580.89
353_N386_M0.9560.88
207_I266_I0.9550.88
594_N668_F0.9540.88
39_R43_S0.9540.88
601_K639_A0.9490.88
580_A583_E0.9480.88
7_E44_I0.9470.88
578_C588_L0.9430.88
94_L114_D0.9390.88
578_C581_E0.9390.88
405_E408_K0.9380.87
562_Q611_K0.9360.87
156_A159_K0.9340.87
432_R436_E0.9320.87
119_N147_G0.9320.87
67_G72_K0.9310.87
10_L44_I0.9290.87
95_I251_L0.9270.87
197_S200_E0.9260.87
120_A123_S0.9220.87
286_I289_H0.9210.87
635_L654_I0.9200.86
555_L559_L0.9180.86
633_R664_S0.9150.86
600_L605_I0.9120.86
230_H399_H0.9110.86
356_I395_F0.9080.86
425_S586_G0.9070.86
100_L160_I0.9040.85
670_E676_L0.9040.85
54_T66_V0.9000.85
539_R542_T0.8970.85
109_Y113_H0.8940.85
336_Y340_I0.8940.85
260_Y291_R0.8940.85
345_P349_R0.8930.85
429_L482_L0.8910.85
559_L562_Q0.8900.85
538_L543_L0.8890.85
589_G648_S0.8880.84
549_N613_F0.8870.84
544_A611_K0.8850.84
563_L609_F0.8830.84
433_L440_I0.8830.84
314_T336_Y0.8830.84
372_Y390_D0.8820.84
254_L287_T0.8770.84
205_E224_Y0.8760.84
209_F224_Y0.8760.84
291_R348_S0.8740.84
358_N365_K0.8730.83
346_A388_F0.8700.83
375_I378_G0.8700.83
85_E90_E0.8650.83
319_A323_D0.8640.83
219_L290_L0.8600.83
22_T62_G0.8600.83
5_A9_K0.8580.82
556_L582_R0.8570.82
558_E561_Q0.8560.82
569_I605_I0.8540.82
279_P289_H0.8510.82
343_L346_A0.8510.82
313_Q317_L0.8480.82
85_E94_L0.8470.82
234_A238_I0.8460.81
419_C423_I0.8460.81
152_G237_R0.8420.81
482_L487_A0.8410.81
582_R636_V0.8410.81
347_V386_M0.8390.81
548_T565_K0.8360.81
616_S671_E0.8340.81
23_V62_G0.8340.81
570_R574_K0.8330.80
338_G402_S0.8320.80
540_H673_G0.8320.80
292_S399_H0.8310.80
244_I285_Y0.8310.80
259_E292_S0.8290.80
667_G676_L0.8280.80
230_H234_A0.8280.80
278_I286_I0.8270.80
91_R117_V0.8260.80
347_V351_K0.8260.80
133_I138_L0.8250.80
310_T340_I0.8250.80
576_A579_L0.8240.80
318_I321_I0.8230.80
359_P395_F0.8220.80
112_A148_I0.8210.80
244_I282_E0.8210.80
314_T318_I0.8200.79
657_A663_E0.8200.79
563_L611_K0.8170.79
589_G651_L0.8150.79
561_Q576_A0.8140.79
654_I658_I0.8120.79
211_L265_E0.8120.79
136_F160_I0.8100.79
35_R40_E0.8090.79
414_K443_F0.8080.78
147_G422_G0.8080.78
413_V461_M0.8070.78
425_S466_V0.8070.78
338_G399_H0.8050.78
22_T27_A0.8030.78
267_A286_I0.8010.78
314_T317_L0.8000.78
211_L269_E0.8000.78
251_L284_G0.7990.78
319_A330_T0.7980.78
196_V232_T0.7980.78
58_Q62_G0.7970.77
574_K588_L0.7970.77
331_K407_K0.7970.77
338_G427_K0.7950.77
88_A91_R0.7950.77
600_L604_E0.7940.77
419_C465_T0.7930.77
560_F579_L0.7910.77
320_F378_G0.7900.77
637_M655_S0.7870.77
211_L262_S0.7870.77
674_Q678_Q0.7860.76
207_I269_E0.7850.76
564_K575_A0.7840.76
10_L40_E0.7840.76
346_A389_S0.7840.76
552_H586_G0.7840.76
546_L550_P0.7820.76
373_M376_E0.7820.76
313_Q383_F0.7810.76
422_G428_M0.7800.76
100_L138_L0.7780.76
96_L150_L0.7760.76
10_L21_I0.7760.76
552_H589_G0.7760.76
263_A267_A0.7760.76
87_S91_R0.7750.75
107_K119_N0.7740.75
422_G466_V0.7740.75
429_L487_A0.7730.75
115_L122_V0.7730.75
10_L30_M0.7730.75
559_L575_A0.7710.75
119_N123_S0.7700.75
13_H417_V0.7680.75
6_R32_V0.7680.75
92_K132_W0.7680.75
356_I391_D0.7680.75
17_Q21_I0.7660.75
542_T611_K0.7640.74
106_V111_L0.7630.74
267_A283_V0.7620.74
593_T621_V0.7610.74
415_A442_S0.7600.74
614_D676_L0.7590.74
575_A638_M0.7580.74
212_K449_I0.7580.74
654_I680_L0.7580.74
152_G158_R0.7570.74
320_F324_K0.7560.74
257_A287_T0.7550.74
399_H406_I0.7530.73
38_H655_S0.7510.73
430_A445_M0.7510.73
586_G589_G0.7460.73
91_R94_L0.7420.72
41_L58_Q0.7420.72
66_V69_P0.7410.72
575_A598_Y0.7390.72
439_E491_K0.7380.72
204_M231_L0.7370.72
255_M260_Y0.7370.72
260_Y284_G0.7370.72
419_C447_S0.7370.72
3_M165_I0.7350.72
379_V393_I0.7350.72
333_Y337_E0.7340.71
361_K391_D0.7320.71
396_I424_G0.7320.71
543_L612_M0.7300.71
318_I400_F0.7300.71
615_L619_Y0.7300.71
346_A354_I0.7290.71
359_P364_I0.7290.71
535_Q681_N0.7290.71
455_D459_Y0.7280.71
257_A291_R0.7280.71
605_I676_L0.7270.71
550_P617_T0.7270.71
4_T40_E0.7260.71
223_S293_A0.7250.71
339_L399_H0.7250.71
552_H588_L0.7240.70
119_N424_G0.7240.70
480_P605_I0.7210.70
488_N491_K0.7210.70
200_E236_E0.7210.70
454_K459_Y0.7210.70
349_R358_N0.7180.70
556_L579_L0.7150.69
350_I389_S0.7140.69
532_E536_D0.7130.69
446_S454_K0.7130.69
579_L600_L0.7120.69
601_K648_S0.7120.69
421_S424_G0.7110.69
282_E395_F0.7090.69
254_L284_G0.7090.69
557_L580_A0.7080.69
123_S148_I0.7020.68
350_I392_E0.7020.68
550_P615_L0.7020.68
230_H233_Y0.7020.68
59_P63_L0.7010.68
26_L40_E0.7000.68
53_L75_L0.7000.68
639_A651_L0.6980.68
14_L44_I0.6960.67
285_Y585_Q0.6950.67
665_M668_F0.6950.67
221_D447_S0.6950.67
221_D449_I0.6940.67
107_K123_S0.6930.67
329_L404_L0.6910.67
538_L673_G0.6890.67
540_H677_Y0.6890.67
414_K444_D0.6870.66
482_L486_D0.6870.66
488_N617_T0.6870.66
417_V430_A0.6860.66
462_I473_I0.6840.66
107_K143_K0.6840.66
609_F638_M0.6830.66
232_T236_E0.6820.66
72_K75_L0.6810.66
105_P147_G0.6810.66
562_Q565_K0.6790.65
579_L588_L0.6790.65
112_A117_V0.6770.65
589_G596_A0.6770.65
451_L470_Y0.6760.65
55_L472_N0.6750.65
20_Y61_K0.6750.65
545_Q616_S0.6730.65
374_A378_G0.6720.65
657_A667_G0.6720.65
246_M281_A0.6720.65
675_E678_Q0.6710.65
551_D557_L0.6700.64
45_K63_L0.6670.64
358_N393_I0.6670.64
289_H399_H0.6660.64
339_L615_L0.6650.64
592_G621_V0.6640.64
153_P412_K0.6640.64
582_R596_A0.6640.64
140_L544_A0.6630.64
480_P486_D0.6620.64
444_D454_K0.6620.64
547_K615_L0.6620.64
416_L456_V0.6610.63
415_A461_M0.6610.63
53_L65_A0.6600.63
558_E613_F0.6590.63
325_I605_I0.6590.63
17_Q25_E0.6590.63
575_A588_L0.6580.63
622_D631_M0.6580.63
582_R590_I0.6580.63
579_L611_K0.6570.63
322_S330_T0.6560.63
35_R62_G0.6550.63
419_C425_S0.6540.63
158_R234_A0.6540.63
244_I479_S0.6530.62
349_R356_I0.6530.62
666_A675_E0.6530.62
124_Y426_S0.6520.62
74_K78_D0.6520.62
267_A276_V0.6510.62
350_I386_M0.6510.62
451_L462_I0.6500.62
555_L619_Y0.6490.62
429_L432_R0.6490.62
335_L338_G0.6480.62
260_Y280_E0.6480.62
311_A340_I0.6470.62
601_K605_I0.6460.62
432_R585_Q0.6450.62
580_A588_L0.6450.62
421_S426_S0.6450.62
546_L613_F0.6440.61
38_H449_I0.6430.61
107_K144_R0.6430.61
660_E663_E0.6430.61
126_L130_E0.6430.61
146_F394_A0.6420.61
134_S139_T0.6410.61
563_L568_L0.6410.61
371_L404_L0.6400.61
575_A582_R0.6400.61
588_L639_A0.6400.61
623_G630_R0.6390.61
578_C600_L0.6380.61
260_Y263_A0.6370.61
148_I321_I0.6370.61
576_A582_R0.6360.60
53_L72_K0.6360.60
582_R586_G0.6340.60
105_P146_F0.6340.60
317_L339_L0.6340.60
651_L655_S0.6330.60
584_K590_I0.6330.60
433_L463_V0.6330.60
123_S142_R0.6310.60
207_I270_L0.6310.60
553_S580_A0.6310.60
316_R382_Y0.6300.60
126_L129_L0.6300.60
271_E278_I0.6300.60
14_L63_L0.6300.60
474_D493_Y0.6290.60
123_S395_F0.6290.60
562_Q613_F0.6280.59
665_M669_Q0.6260.59
610_F654_I0.6250.59
488_N492_Q0.6250.59
358_N368_Y0.6240.59
23_V27_A0.6210.59
163_N394_A0.6200.58
32_V321_I0.6200.58
43_S46_P0.6180.58
442_S459_Y0.6180.58
677_Y681_N0.6180.58
578_C601_K0.6180.58
402_S405_E0.6180.58
109_Y146_F0.6170.58
364_I398_L0.6170.58
342_H395_F0.6170.58
345_P348_S0.6170.58
14_L27_A0.6170.58
224_Y228_V0.6170.58
563_L567_G0.6160.58
338_G403_A0.6150.58
666_A669_Q0.6130.58
635_L638_M0.6110.57
398_L402_S0.6100.57
534_I650_I0.6090.57
95_I133_I0.6090.57
254_L257_A0.6080.57
487_A536_D0.6080.57
138_L160_I0.6060.57
555_L562_Q0.6060.57
7_E84_H0.6060.57
597_L610_F0.6040.57
605_I609_F0.6030.56
207_I210_Q0.6030.56
46_P50_T0.6030.56
350_I388_F0.6030.56
33_S322_S0.6020.56
364_I394_A0.6020.56
35_R38_H0.6020.56
27_A62_G0.6010.56
247_E251_L0.6010.56
147_G428_M0.6010.56
588_L593_T0.6010.56
254_L291_R0.6010.56
196_V200_E0.5990.56
590_I629_L0.5990.56
35_R58_Q0.5990.56
198_K201_L0.5980.56
554_M669_Q0.5980.56
417_V426_S0.5970.56
633_R676_L0.5970.56
270_L282_E0.5970.56
561_Q564_K0.5960.56
592_G629_L0.5960.56
289_H354_I0.5950.55
77_T554_M0.5930.55
360_M395_F0.5930.55
618_P630_R0.5930.55
220_S223_S0.5910.55
300_E634_I0.5900.55
461_M490_V0.5900.55
291_R352_E0.5900.55
57_K62_G0.5890.55
122_V212_K0.5880.55
165_I203_K0.5870.54
107_K145_G0.5870.54
108_L122_V0.5860.54
318_I322_S0.5850.54
122_V680_L0.5840.54
260_Y264_L0.5840.54
126_L148_I0.5830.54
586_G651_L0.5830.54
328_D332_N0.5830.54
139_T362_E0.5830.54
414_K460_D0.5810.54
612_M635_L0.5810.54
239_K275_G0.5810.54
55_L58_Q0.5800.54
420_S448_L0.5790.53
546_L549_N0.5790.53
376_E586_G0.5790.53
343_L361_K0.5770.53
448_L466_V0.5760.53
162_G289_H0.5760.53
271_E274_F0.5750.53
334_S338_G0.5750.53
279_P288_I0.5750.53
267_A274_F0.5740.53
208_L657_A0.5730.53
559_L582_R0.5730.53
648_S651_L0.5730.53
144_R415_A0.5720.53
86_Y90_E0.5710.52
6_R10_L0.5710.52
98_S111_L0.5710.52
27_A294_N0.5710.52
547_K550_P0.5700.52
154_E241_G0.5690.52
140_L655_S0.5680.52
639_A648_S0.5670.52
476_I490_V0.5670.52
394_A397_V0.5650.52
35_R63_L0.5650.52
342_H392_E0.5640.52
575_A601_K0.5640.52
3_M47_L0.5640.52
638_M655_S0.5630.51
204_M207_I0.5630.51
378_G610_F0.5630.51
606_V609_F0.5620.51
268_G318_I0.5620.51
581_E588_L0.5610.51
401_G420_S0.5600.51
379_V397_V0.5600.51
77_T309_E0.5600.51
582_R598_Y0.5590.51
583_E621_V0.5590.51
160_I164_L0.5580.51
83_Q247_E0.5580.51
402_S442_S0.5580.51
98_S115_L0.5580.51
621_V640_P0.5550.50
317_L379_V0.5540.50
437_L463_V0.5540.50
222_S226_A0.5530.50
427_K445_M0.5530.50
633_R638_M0.5520.50
443_F459_Y0.5520.50
578_C586_G0.5520.50
147_G285_Y0.5510.50
434_K443_F0.5510.50
57_K263_A0.5510.50
327_M404_L0.5510.50
564_K576_A0.5510.50
598_Y633_R0.5510.50
442_S463_V0.5500.50
434_K484_E0.5500.50
140_L441_E0.5500.50
450_E453_G0.5490.50
65_A634_I0.5470.49
230_H395_F0.5460.49
429_L478_V0.5460.49
63_L673_G0.5460.49
39_R42_K0.5460.49
316_R319_A0.5450.49
107_K438_P0.5450.49
359_P394_A0.5450.49
603_D641_G0.5450.49
359_P422_G0.5450.49
196_V201_L0.5450.49
220_S346_A0.5440.49
582_R621_V0.5440.49
206_R210_Q0.5440.49
35_R257_A0.5440.49
555_L598_Y0.5430.49
230_H279_P0.5430.49
127_D285_Y0.5430.49
241_G282_E0.5430.49
346_A676_L0.5410.49
266_I414_K0.5390.48
106_V353_N0.5390.48
433_L490_V0.5390.48
356_I396_I0.5390.48
574_K604_E0.5380.48
324_K378_G0.5380.48
154_E157_K0.5370.48
368_Y432_R0.5370.48
546_L606_V0.5370.48
292_S354_I0.5360.48
480_P483_N0.5360.48
559_L621_V0.5340.48
263_A286_I0.5330.48
259_E290_L0.5320.47
589_G629_L0.5310.47
365_K394_A0.5310.47
598_Y638_M0.5310.47
590_I621_V0.5300.47
383_F386_M0.5290.47
622_D629_L0.5290.47
261_S264_L0.5290.47
267_A284_G0.5280.47
205_E316_R0.5280.47
140_L389_S0.5270.47
52_G114_D0.5270.47
4_T598_Y0.5260.47
608_P646_E0.5260.47
575_A636_V0.5260.47
548_T669_Q0.5260.47
577_V580_A0.5250.47
7_E420_S0.5250.47
400_F459_Y0.5250.47
92_K115_L0.5250.47
653_A680_L0.5250.47
322_S329_L0.5240.46
236_E239_K0.5240.46
554_M558_E0.5240.46
310_T383_F0.5240.46
432_R482_L0.5240.46
588_L647_G0.5230.46
401_G423_I0.5230.46
9_K13_H0.5230.46
119_N638_M0.5220.46
264_L314_T0.5210.46
579_L610_F0.5210.46
291_R462_I0.5210.46
552_H580_A0.5200.46
11_L136_F0.5190.46
285_Y440_I0.5190.46
355_E378_G0.5190.46
288_I494_I0.5190.46
10_L336_Y0.5180.46
294_N427_K0.5180.46
266_I347_V0.5180.46
574_K654_I0.5180.46
602_N605_I0.5180.46
423_I426_S0.5170.46
650_I653_A0.5170.46
555_L650_I0.5170.46
560_F575_A0.5170.46
364_I397_V0.5160.45
21_I316_R0.5150.45
204_M270_L0.5150.45
663_E679_R0.5150.45
33_S62_G0.5150.45
279_P286_I0.5140.45
106_V114_D0.5140.45
465_T480_P0.5140.45
244_I263_A0.5130.45
127_D142_R0.5130.45
349_R394_A0.5130.45
132_W136_F0.5130.45
493_Y496_R0.5120.45
641_G647_G0.5120.45
635_L657_A0.5120.45
639_A647_G0.5110.45
129_L150_L0.5110.45
96_L318_I0.5110.45
99_L150_L0.5110.45
345_P356_I0.5110.45
371_L374_A0.5110.45
213_E216_A0.5100.45
266_I561_Q0.5100.45
107_K345_P0.5100.45
563_L598_Y0.5100.45
573_E662_G0.5090.45
621_V636_V0.5080.44
589_G622_D0.5070.44
23_V38_H0.5060.44
575_A586_G0.5060.44
147_G419_C0.5050.44
208_L418_V0.5050.44
251_L255_M0.5040.44
617_T632_T0.5040.44
652_S655_S0.5030.44
590_I655_S0.5030.44
478_V486_D0.5020.44
534_I664_S0.5020.44
281_A284_G0.5020.44
338_G401_G0.5020.44
160_I294_N0.5010.44
282_E364_I0.5010.44
552_H578_C0.5010.44
57_K438_P0.5010.44
598_Y621_V0.5010.44
237_R463_V0.5000.43
45_K605_I0.5000.43
542_T610_F0.5000.43
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4r6iA 2 0.6542 100 0.47 Contact Map
3sqnA 2 0.6499 100 0.52 Contact Map
1h99A 2 0.3127 100 0.778 Contact Map
1a6jA 4 0.2233 100 0.8 Contact Map
3urrA 2 0.219 100 0.804 Contact Map
3oxpA 2 0.2104 100 0.804 Contact Map
2a0jA 1 0.2104 100 0.805 Contact Map
1a3aA 2 0.2061 100 0.81 Contact Map
2oq3A 1 0.2089 100 0.81 Contact Map
4m62S 1 0.2147 100 0.811 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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