MTLR - BACSU - GREMLIN Contacts

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MTLR - Transcriptional regulator MtlR

UniProt:	P96574	Sequences: MYMTAREQKLLKHLLLQNRYITVTELAELMQVSTRTIHRELKSIKPLMETVGLTLDKQPGKGLKAVGSPEGKQKLLTDLSYEQHEYSADERKLLILCSLLESQEPVKLYTLAHDLQVTNATVSYDLDELEKWISPFGLTLIRKRGFGIQLIGPENAKRKIVGNLIVNRLDIQMFLEAVELNIKGKTDSSEKMFGVVSKGELLKMERILFQLKEKIAFSLSDSSYIALVVHLTYAIERIKLGETITMEQNELEELMNAKEYSSALEIAGELERAFGVTIPEAEVGYITIHLRSANRKYKTEYKAQEIELETALQTKRLIAFISDKIRMDLTKNYSLYEGLIAHLEPAVSRIKENIEIYNPMKEQIKRDYFLLYMAIEEGVEKYFPGMSFSDDEIAFIVLHFGSALEIKKEEAKVKALVVCSSGIGSSKMLASRLKKELPEIESFDMSSLIELKGKDVQAYDMIVSTVPIPYENIDYIMVSPLLNEEDANQVKQYIKRKIPLILNKKRSSKEEAQQADVPDMLEAAESIGRYMEVIQDVLRHFTLAQLKTNPDHSMLLLELFQQLKKDGLIRDPEKAAVCLAEREKQGGLGIPGTNMALYHLKNDEIVLPFFKMFDLSTPYEVDGMDGNTLRMTRILVMMAPGSLSAEGSEILSAISSAIIESGESMAGFQEEGGQELYQRLNRIFFTWMKEKNIL	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	694 (626)
Sequences:	2180 (1889)
Seq/√Len:	75.5

ECOLI - FRVR
BACSU - MTLR MANR LICR

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
6_R	40_E	5.606	1.00
154_E	237_R	4.558	1.00
91_R	125_D	4.347	1.00
365_K	390_D	4.050	1.00
332_N	406_I	4.011	1.00
414_K	441_E	3.821	1.00
32_V	37_I	3.750	1.00
672_G	675_E	3.700	1.00
138_L	152_G	3.609	1.00
214_K	265_E	3.546	1.00
41_L	45_K	3.543	1.00
117_V	122_V	3.491	1.00
548_T	616_S	3.417	1.00
361_K	394_A	3.411	1.00
98_S	114_D	3.303	1.00
137_G	156_A	3.193	1.00
615_L	618_P	3.159	1.00
117_V	125_D	3.012	1.00
154_E	158_R	3.012	1.00
416_L	446_S	2.882	1.00
632_T	668_F	2.875	1.00
557_L	576_A	2.808	1.00
136_F	163_N	2.752	1.00
158_R	282_E	2.693	1.00
553_S	583_E	2.664	1.00
322_S	328_D	2.643	1.00
419_C	422_G	2.588	1.00
540_H	674_Q	2.562	1.00
138_L	150_L	2.560	1.00
541_F	566_D	2.501	1.00
551_D	554_M	2.499	1.00
130_E	142_R	2.479	1.00
467_P	477_M	2.431	1.00
315_K	336_Y	2.392	1.00
158_R	237_R	2.387	1.00
605_I	638_M	2.355	1.00
430_A	434_K	2.353	1.00
543_L	673_G	2.331	1.00
117_V	121_T	2.322	1.00
417_V	433_L	2.280	1.00
332_N	403_A	2.276	1.00
36_T	40_E	2.273	1.00
559_L	613_F	2.237	1.00
13_H	26_L	2.236	1.00
381_K	387_S	2.224	1.00
429_L	465_T	2.195	1.00
153_P	156_A	2.180	1.00
549_N	558_E	2.152	1.00
570_R	606_V	2.150	1.00
415_A	463_V	2.135	1.00
32_V	40_E	2.132	1.00
427_K	430_A	2.113	1.00
555_L	613_F	2.094	1.00
329_L	400_F	2.082	1.00
230_H	289_H	2.074	1.00
13_H	21_I	2.058	1.00
45_K	57_K	2.058	1.00
559_L	636_V	2.005	1.00
359_P	391_D	1.997	1.00
365_K	372_Y	1.979	1.00
556_L	576_A	1.973	1.00
564_K	569_I	1.970	1.00
26_L	37_I	1.969	1.00
568_L	607_L	1.960	1.00
560_F	576_A	1.947	1.00
415_A	440_I	1.921	1.00
255_M	280_E	1.916	1.00
618_P	632_T	1.913	1.00
561_Q	565_K	1.909	1.00
56_D	66_V	1.899	1.00
582_R	588_L	1.870	1.00
45_K	55_L	1.862	1.00
664_S	668_F	1.855	1.00
84_H	90_E	1.849	1.00
376_E	390_D	1.845	1.00
34_T	38_H	1.843	1.00
375_I	397_V	1.841	1.00
314_T	343_L	1.838	1.00
574_K	578_C	1.833	1.00
210_Q	269_E	1.829	1.00
419_C	426_S	1.811	1.00
596_A	631_M	1.805	1.00
578_C	582_R	1.763	1.00
546_L	614_D	1.760	1.00
271_E	277_T	1.758	1.00
479_S	486_D	1.754	1.00
143_K	146_F	1.754	1.00
548_T	617_T	1.740	1.00
132_W	160_I	1.738	1.00
321_I	374_A	1.734	1.00
545_Q	614_D	1.727	1.00
358_N	394_A	1.725	1.00
20_Y	64_K	1.725	1.00
560_F	636_V	1.721	1.00
555_L	634_I	1.709	1.00
6_R	36_T	1.706	1.00
324_K	377_E	1.694	1.00
141_I	151_I	1.688	1.00
552_H	621_V	1.679	1.00
317_L	400_F	1.679	1.00
152_G	157_K	1.666	1.00
486_D	489_Q	1.663	1.00
358_N	391_D	1.658	1.00
608_P	640_P	1.654	1.00
568_L	609_F	1.653	1.00
379_V	396_I	1.643	1.00
346_A	350_I	1.632	1.00
322_S	332_N	1.631	1.00
129_L	140_L	1.623	1.00
582_R	589_G	1.619	1.00
547_K	613_F	1.616	1.00
594_N	632_T	1.615	1.00
92_K	129_L	1.605	1.00
96_L	129_L	1.600	0.99
620_E	623_G	1.594	0.99
7_E	43_S	1.591	0.99
13_H	29_L	1.591	0.99
162_G	230_H	1.563	0.99
542_T	566_D	1.555	0.99
357_Y	391_D	1.554	0.99
371_L	397_V	1.551	0.99
588_L	621_V	1.532	0.99
610_F	635_L	1.525	0.99
570_R	573_E	1.522	0.99
226_A	289_H	1.508	0.99
559_L	611_K	1.499	0.99
208_L	228_V	1.495	0.99
437_L	491_K	1.491	0.99
349_R	392_E	1.487	0.99
109_Y	119_N	1.480	0.99
58_Q	61_K	1.479	0.99
463_V	478_V	1.475	0.99
231_L	286_I	1.468	0.99
264_L	283_V	1.465	0.99
490_V	494_I	1.463	0.99
4_T	7_E	1.463	0.99
339_L	396_I	1.462	0.99
482_L	490_V	1.456	0.99
447_S	450_E	1.456	0.99
59_P	62_G	1.456	0.99
553_S	557_L	1.453	0.99
13_H	30_M	1.453	0.99
321_I	400_F	1.452	0.99
257_A	260_Y	1.448	0.99
41_L	63_L	1.447	0.99
321_I	375_I	1.445	0.99
549_N	555_L	1.443	0.99
335_L	339_L	1.441	0.99
318_I	336_Y	1.433	0.99
215_I	265_E	1.430	0.99
325_I	374_A	1.430	0.99
544_A	562_Q	1.428	0.99
567_G	606_V	1.422	0.99
10_L	26_L	1.418	0.99
226_A	230_H	1.417	0.99
413_V	494_I	1.415	0.99
87_S	90_E	1.408	0.99
412_K	441_E	1.406	0.99
334_S	406_I	1.404	0.99
342_H	399_H	1.403	0.99
575_A	579_L	1.402	0.99
576_A	580_A	1.400	0.99
335_L	403_A	1.396	0.99
671_E	675_E	1.393	0.99
53_L	67_G	1.378	0.98
27_A	34_T	1.372	0.98
35_R	401_G	1.370	0.98
211_L	266_I	1.367	0.98
193_F	196_V	1.366	0.98
543_L	614_D	1.362	0.98
574_K	580_A	1.360	0.98
552_H	622_D	1.353	0.98
335_L	406_I	1.352	0.98
419_C	466_V	1.352	0.98
14_L	65_A	1.350	0.98
20_Y	62_G	1.348	0.98
623_G	629_L	1.348	0.98
547_K	616_S	1.343	0.98
329_L	403_A	1.343	0.98
138_L	157_K	1.335	0.98
96_L	133_I	1.333	0.98
154_E	282_E	1.330	0.98
24_T	28_E	1.313	0.98
546_L	616_S	1.310	0.98
107_K	147_G	1.309	0.98
316_R	383_F	1.305	0.98
11_L	44_I	1.302	0.98
91_R	121_T	1.298	0.98
633_R	668_F	1.296	0.98
95_I	129_L	1.287	0.98
583_E	588_L	1.285	0.98
563_L	569_I	1.284	0.98
463_V	476_I	1.277	0.97
259_E	287_T	1.266	0.97
260_Y	287_T	1.265	0.97
358_N	395_F	1.265	0.97
569_I	575_A	1.265	0.97
144_R	147_G	1.265	0.97
162_G	233_Y	1.262	0.97
538_L	612_M	1.261	0.97
27_A	37_I	1.257	0.97
105_P	149_Q	1.256	0.97
608_P	639_A	1.253	0.97
88_A	128_E	1.252	0.97
279_P	282_E	1.245	0.97
670_E	679_R	1.242	0.97
415_A	494_I	1.241	0.97
579_L	636_V	1.239	0.97
7_E	40_E	1.238	0.97
56_D	64_K	1.236	0.97
444_D	459_Y	1.236	0.97
464_S	477_M	1.234	0.97
139_T	151_I	1.232	0.97
420_S	466_V	1.230	0.97
459_Y	473_I	1.229	0.97
23_V	63_L	1.221	0.97
24_T	34_T	1.219	0.97
371_L	375_I	1.215	0.97
92_K	128_E	1.215	0.97
399_H	402_S	1.211	0.97
361_K	390_D	1.211	0.97
650_I	654_I	1.209	0.96
581_E	584_K	1.209	0.96
346_A	349_R	1.206	0.96
371_L	401_G	1.202	0.96
342_H	599_H	1.199	0.96
416_L	459_Y	1.197	0.96
620_E	630_R	1.189	0.96
116_Q	621_V	1.188	0.96
107_K	110_T	1.188	0.96
111_L	122_V	1.184	0.96
32_V	36_T	1.183	0.96
422_G	425_S	1.182	0.96
33_S	36_T	1.180	0.96
238_I	282_E	1.177	0.96
263_A	283_V	1.174	0.96
615_L	632_T	1.172	0.96
554_M	557_L	1.172	0.96
264_L	280_E	1.170	0.96
141_I	149_Q	1.168	0.96
92_K	125_D	1.165	0.96
3_M	7_E	1.164	0.96
88_A	125_D	1.160	0.96
203_K	273_A	1.152	0.95
575_A	578_C	1.152	0.95
673_G	676_L	1.148	0.95
4_T	43_S	1.147	0.95
673_G	677_Y	1.144	0.95
418_V	468_I	1.140	0.95
27_A	32_V	1.138	0.95
13_H	17_Q	1.135	0.95
614_D	633_R	1.133	0.95
574_K	577_V	1.133	0.95
212_K	219_L	1.132	0.95
569_I	638_M	1.128	0.95
35_R	39_R	1.126	0.95
220_S	294_N	1.124	0.95
94_L	115_L	1.123	0.95
552_H	582_R	1.123	0.95
292_S	345_P	1.118	0.95
402_S	406_I	1.116	0.94
550_P	554_M	1.115	0.94
612_M	676_L	1.115	0.94
589_G	621_V	1.114	0.94
405_E	432_R	1.113	0.94
254_L	260_Y	1.112	0.94
578_C	589_G	1.111	0.94
600_L	638_M	1.109	0.94
560_F	564_K	1.106	0.94
238_I	278_I	1.105	0.94
259_E	291_R	1.105	0.94
263_A	287_T	1.104	0.94
422_G	426_S	1.104	0.94
575_A	580_A	1.098	0.94
310_T	314_T	1.088	0.94
129_L	133_I	1.085	0.94
71_G	74_K	1.080	0.93
538_L	542_T	1.079	0.93
41_L	55_L	1.078	0.93
621_V	634_I	1.074	0.93
542_T	568_L	1.074	0.93
204_M	232_T	1.074	0.93
338_G	406_I	1.074	0.93
421_S	425_S	1.073	0.93
476_I	486_D	1.068	0.93
610_F	650_I	1.067	0.93
122_V	129_L	1.064	0.93
436_E	491_K	1.062	0.93
574_K	582_R	1.060	0.93
317_L	375_I	1.057	0.93
122_V	125_D	1.053	0.93
403_A	406_I	1.052	0.93
107_K	146_F	1.050	0.92
332_N	405_E	1.048	0.92
647_G	651_L	1.047	0.92
414_K	458_A	1.042	0.92
544_A	558_E	1.037	0.92
556_L	636_V	1.035	0.92
493_Y	497_K	1.034	0.92
236_E	240_L	1.033	0.92
546_L	615_L	1.032	0.92
142_R	148_I	1.031	0.92
556_L	560_F	1.030	0.92
558_E	562_Q	1.029	0.92
464_S	475_Y	1.028	0.92
112_A	122_V	1.027	0.92
596_A	621_V	1.026	0.92
287_T	291_R	1.025	0.92
263_A	290_L	1.023	0.91
325_I	329_L	1.022	0.91
375_I	379_V	1.022	0.91
30_M	37_I	1.022	0.91
285_Y	359_P	1.016	0.91
237_R	282_E	1.015	0.91
317_L	378_G	1.014	0.91
263_A	266_I	1.013	0.91
57_K	63_L	1.009	0.91
121_T	125_D	1.007	0.91
293_A	346_A	1.006	0.91
108_L	119_N	1.005	0.91
588_L	598_Y	1.001	0.91
432_R	481_L	0.998	0.90
436_E	487_A	0.997	0.90
379_V	388_F	0.993	0.90
419_C	424_G	0.991	0.90
260_Y	283_V	0.990	0.90
478_V	482_L	0.989	0.90
621_V	631_M	0.988	0.90
372_Y	376_E	0.986	0.90
670_E	675_E	0.986	0.90
318_I	335_L	0.986	0.90
205_E	225_I	0.984	0.90
320_F	323_D	0.981	0.90
36_T	39_R	0.979	0.90
391_D	394_A	0.977	0.89
267_A	271_E	0.976	0.89
543_L	676_L	0.975	0.89
363_Q	367_D	0.970	0.89
335_L	378_G	0.970	0.89
577_V	581_E	0.965	0.89
437_L	487_A	0.964	0.89
314_T	340_I	0.964	0.89
549_N	615_L	0.962	0.89
399_H	424_G	0.961	0.89
96_L	164_L	0.959	0.89
207_I	211_L	0.958	0.89
353_N	386_M	0.956	0.88
207_I	266_I	0.955	0.88
594_N	668_F	0.954	0.88
39_R	43_S	0.954	0.88
601_K	639_A	0.949	0.88
580_A	583_E	0.948	0.88
7_E	44_I	0.947	0.88
578_C	588_L	0.943	0.88
94_L	114_D	0.939	0.88
578_C	581_E	0.939	0.88
405_E	408_K	0.938	0.87
562_Q	611_K	0.936	0.87
156_A	159_K	0.934	0.87
432_R	436_E	0.932	0.87
119_N	147_G	0.932	0.87
67_G	72_K	0.931	0.87
10_L	44_I	0.929	0.87
95_I	251_L	0.927	0.87
197_S	200_E	0.926	0.87
120_A	123_S	0.922	0.87
286_I	289_H	0.921	0.87
635_L	654_I	0.920	0.86
555_L	559_L	0.918	0.86
633_R	664_S	0.915	0.86
600_L	605_I	0.912	0.86
230_H	399_H	0.911	0.86
356_I	395_F	0.908	0.86
425_S	586_G	0.907	0.86
100_L	160_I	0.904	0.85
670_E	676_L	0.904	0.85
54_T	66_V	0.900	0.85
539_R	542_T	0.897	0.85
109_Y	113_H	0.894	0.85
336_Y	340_I	0.894	0.85
260_Y	291_R	0.894	0.85
345_P	349_R	0.893	0.85
429_L	482_L	0.891	0.85
559_L	562_Q	0.890	0.85
538_L	543_L	0.889	0.85
589_G	648_S	0.888	0.84
549_N	613_F	0.887	0.84
544_A	611_K	0.885	0.84
563_L	609_F	0.883	0.84
433_L	440_I	0.883	0.84
314_T	336_Y	0.883	0.84
372_Y	390_D	0.882	0.84
254_L	287_T	0.877	0.84
205_E	224_Y	0.876	0.84
209_F	224_Y	0.876	0.84
291_R	348_S	0.874	0.84
358_N	365_K	0.873	0.83
346_A	388_F	0.870	0.83
375_I	378_G	0.870	0.83
85_E	90_E	0.865	0.83
319_A	323_D	0.864	0.83
219_L	290_L	0.860	0.83
22_T	62_G	0.860	0.83
5_A	9_K	0.858	0.82
556_L	582_R	0.857	0.82
558_E	561_Q	0.856	0.82
569_I	605_I	0.854	0.82
279_P	289_H	0.851	0.82
343_L	346_A	0.851	0.82
313_Q	317_L	0.848	0.82
85_E	94_L	0.847	0.82
234_A	238_I	0.846	0.81
419_C	423_I	0.846	0.81
152_G	237_R	0.842	0.81
482_L	487_A	0.841	0.81
582_R	636_V	0.841	0.81
347_V	386_M	0.839	0.81
548_T	565_K	0.836	0.81
616_S	671_E	0.834	0.81
23_V	62_G	0.834	0.81
570_R	574_K	0.833	0.80
338_G	402_S	0.832	0.80
540_H	673_G	0.832	0.80
292_S	399_H	0.831	0.80
244_I	285_Y	0.831	0.80
259_E	292_S	0.829	0.80
667_G	676_L	0.828	0.80
230_H	234_A	0.828	0.80
278_I	286_I	0.827	0.80
91_R	117_V	0.826	0.80
347_V	351_K	0.826	0.80
133_I	138_L	0.825	0.80
310_T	340_I	0.825	0.80
576_A	579_L	0.824	0.80
318_I	321_I	0.823	0.80
359_P	395_F	0.822	0.80
112_A	148_I	0.821	0.80
244_I	282_E	0.821	0.80
314_T	318_I	0.820	0.79
657_A	663_E	0.820	0.79
563_L	611_K	0.817	0.79
589_G	651_L	0.815	0.79
561_Q	576_A	0.814	0.79
654_I	658_I	0.812	0.79
211_L	265_E	0.812	0.79
136_F	160_I	0.810	0.79
35_R	40_E	0.809	0.79
414_K	443_F	0.808	0.78
147_G	422_G	0.808	0.78
413_V	461_M	0.807	0.78
425_S	466_V	0.807	0.78
338_G	399_H	0.805	0.78
22_T	27_A	0.803	0.78
267_A	286_I	0.801	0.78
314_T	317_L	0.800	0.78
211_L	269_E	0.800	0.78
251_L	284_G	0.799	0.78
319_A	330_T	0.798	0.78
196_V	232_T	0.798	0.78
58_Q	62_G	0.797	0.77
574_K	588_L	0.797	0.77
331_K	407_K	0.797	0.77
338_G	427_K	0.795	0.77
88_A	91_R	0.795	0.77
600_L	604_E	0.794	0.77
419_C	465_T	0.793	0.77
560_F	579_L	0.791	0.77
320_F	378_G	0.790	0.77
637_M	655_S	0.787	0.77
211_L	262_S	0.787	0.77
674_Q	678_Q	0.786	0.76
207_I	269_E	0.785	0.76
564_K	575_A	0.784	0.76
10_L	40_E	0.784	0.76
346_A	389_S	0.784	0.76
552_H	586_G	0.784	0.76
546_L	550_P	0.782	0.76
373_M	376_E	0.782	0.76
313_Q	383_F	0.781	0.76
422_G	428_M	0.780	0.76
100_L	138_L	0.778	0.76
96_L	150_L	0.776	0.76
10_L	21_I	0.776	0.76
552_H	589_G	0.776	0.76
263_A	267_A	0.776	0.76
87_S	91_R	0.775	0.75
107_K	119_N	0.774	0.75
422_G	466_V	0.774	0.75
429_L	487_A	0.773	0.75
115_L	122_V	0.773	0.75
10_L	30_M	0.773	0.75
559_L	575_A	0.771	0.75
119_N	123_S	0.770	0.75
13_H	417_V	0.768	0.75
6_R	32_V	0.768	0.75
92_K	132_W	0.768	0.75
356_I	391_D	0.768	0.75
17_Q	21_I	0.766	0.75
542_T	611_K	0.764	0.74
106_V	111_L	0.763	0.74
267_A	283_V	0.762	0.74
593_T	621_V	0.761	0.74
415_A	442_S	0.760	0.74
614_D	676_L	0.759	0.74
575_A	638_M	0.758	0.74
212_K	449_I	0.758	0.74
654_I	680_L	0.758	0.74
152_G	158_R	0.757	0.74
320_F	324_K	0.756	0.74
257_A	287_T	0.755	0.74
399_H	406_I	0.753	0.73
38_H	655_S	0.751	0.73
430_A	445_M	0.751	0.73
586_G	589_G	0.746	0.73
91_R	94_L	0.742	0.72
41_L	58_Q	0.742	0.72
66_V	69_P	0.741	0.72
575_A	598_Y	0.739	0.72
439_E	491_K	0.738	0.72
204_M	231_L	0.737	0.72
255_M	260_Y	0.737	0.72
260_Y	284_G	0.737	0.72
419_C	447_S	0.737	0.72
3_M	165_I	0.735	0.72
379_V	393_I	0.735	0.72
333_Y	337_E	0.734	0.71
361_K	391_D	0.732	0.71
396_I	424_G	0.732	0.71
543_L	612_M	0.730	0.71
318_I	400_F	0.730	0.71
615_L	619_Y	0.730	0.71
346_A	354_I	0.729	0.71
359_P	364_I	0.729	0.71
535_Q	681_N	0.729	0.71
455_D	459_Y	0.728	0.71
257_A	291_R	0.728	0.71
605_I	676_L	0.727	0.71
550_P	617_T	0.727	0.71
4_T	40_E	0.726	0.71
223_S	293_A	0.725	0.71
339_L	399_H	0.725	0.71
552_H	588_L	0.724	0.70
119_N	424_G	0.724	0.70
480_P	605_I	0.721	0.70
488_N	491_K	0.721	0.70
200_E	236_E	0.721	0.70
454_K	459_Y	0.721	0.70
349_R	358_N	0.718	0.70
556_L	579_L	0.715	0.69
350_I	389_S	0.714	0.69
532_E	536_D	0.713	0.69
446_S	454_K	0.713	0.69
579_L	600_L	0.712	0.69
601_K	648_S	0.712	0.69
421_S	424_G	0.711	0.69
282_E	395_F	0.709	0.69
254_L	284_G	0.709	0.69
557_L	580_A	0.708	0.69
123_S	148_I	0.702	0.68
350_I	392_E	0.702	0.68
550_P	615_L	0.702	0.68
230_H	233_Y	0.702	0.68
59_P	63_L	0.701	0.68
26_L	40_E	0.700	0.68
53_L	75_L	0.700	0.68
639_A	651_L	0.698	0.68
14_L	44_I	0.696	0.67
285_Y	585_Q	0.695	0.67
665_M	668_F	0.695	0.67
221_D	447_S	0.695	0.67
221_D	449_I	0.694	0.67
107_K	123_S	0.693	0.67
329_L	404_L	0.691	0.67
538_L	673_G	0.689	0.67
540_H	677_Y	0.689	0.67
414_K	444_D	0.687	0.66
482_L	486_D	0.687	0.66
488_N	617_T	0.687	0.66
417_V	430_A	0.686	0.66
462_I	473_I	0.684	0.66
107_K	143_K	0.684	0.66
609_F	638_M	0.683	0.66
232_T	236_E	0.682	0.66
72_K	75_L	0.681	0.66
105_P	147_G	0.681	0.66
562_Q	565_K	0.679	0.65
579_L	588_L	0.679	0.65
112_A	117_V	0.677	0.65
589_G	596_A	0.677	0.65
451_L	470_Y	0.676	0.65
55_L	472_N	0.675	0.65
20_Y	61_K	0.675	0.65
545_Q	616_S	0.673	0.65
374_A	378_G	0.672	0.65
657_A	667_G	0.672	0.65
246_M	281_A	0.672	0.65
675_E	678_Q	0.671	0.65
551_D	557_L	0.670	0.64
45_K	63_L	0.667	0.64
358_N	393_I	0.667	0.64
289_H	399_H	0.666	0.64
339_L	615_L	0.665	0.64
592_G	621_V	0.664	0.64
153_P	412_K	0.664	0.64
582_R	596_A	0.664	0.64
140_L	544_A	0.663	0.64
480_P	486_D	0.662	0.64
444_D	454_K	0.662	0.64
547_K	615_L	0.662	0.64
416_L	456_V	0.661	0.63
415_A	461_M	0.661	0.63
53_L	65_A	0.660	0.63
558_E	613_F	0.659	0.63
325_I	605_I	0.659	0.63
17_Q	25_E	0.659	0.63
575_A	588_L	0.658	0.63
622_D	631_M	0.658	0.63
582_R	590_I	0.658	0.63
579_L	611_K	0.657	0.63
322_S	330_T	0.656	0.63
35_R	62_G	0.655	0.63
419_C	425_S	0.654	0.63
158_R	234_A	0.654	0.63
244_I	479_S	0.653	0.62
349_R	356_I	0.653	0.62
666_A	675_E	0.653	0.62
124_Y	426_S	0.652	0.62
74_K	78_D	0.652	0.62
267_A	276_V	0.651	0.62
350_I	386_M	0.651	0.62
451_L	462_I	0.650	0.62
555_L	619_Y	0.649	0.62
429_L	432_R	0.649	0.62
335_L	338_G	0.648	0.62
260_Y	280_E	0.648	0.62
311_A	340_I	0.647	0.62
601_K	605_I	0.646	0.62
432_R	585_Q	0.645	0.62
580_A	588_L	0.645	0.62
421_S	426_S	0.645	0.62
546_L	613_F	0.644	0.61
38_H	449_I	0.643	0.61
107_K	144_R	0.643	0.61
660_E	663_E	0.643	0.61
126_L	130_E	0.643	0.61
146_F	394_A	0.642	0.61
134_S	139_T	0.641	0.61
563_L	568_L	0.641	0.61
371_L	404_L	0.640	0.61
575_A	582_R	0.640	0.61
588_L	639_A	0.640	0.61
623_G	630_R	0.639	0.61
578_C	600_L	0.638	0.61
260_Y	263_A	0.637	0.61
148_I	321_I	0.637	0.61
576_A	582_R	0.636	0.60
53_L	72_K	0.636	0.60
582_R	586_G	0.634	0.60
105_P	146_F	0.634	0.60
317_L	339_L	0.634	0.60
651_L	655_S	0.633	0.60
584_K	590_I	0.633	0.60
433_L	463_V	0.633	0.60
123_S	142_R	0.631	0.60
207_I	270_L	0.631	0.60
553_S	580_A	0.631	0.60
316_R	382_Y	0.630	0.60
126_L	129_L	0.630	0.60
271_E	278_I	0.630	0.60
14_L	63_L	0.630	0.60
474_D	493_Y	0.629	0.60
123_S	395_F	0.629	0.60
562_Q	613_F	0.628	0.59
665_M	669_Q	0.626	0.59
610_F	654_I	0.625	0.59
488_N	492_Q	0.625	0.59
358_N	368_Y	0.624	0.59
23_V	27_A	0.621	0.59
163_N	394_A	0.620	0.58
32_V	321_I	0.620	0.58
43_S	46_P	0.618	0.58
442_S	459_Y	0.618	0.58
677_Y	681_N	0.618	0.58
578_C	601_K	0.618	0.58
402_S	405_E	0.618	0.58
109_Y	146_F	0.617	0.58
364_I	398_L	0.617	0.58
342_H	395_F	0.617	0.58
345_P	348_S	0.617	0.58
14_L	27_A	0.617	0.58
224_Y	228_V	0.617	0.58
563_L	567_G	0.616	0.58
338_G	403_A	0.615	0.58
666_A	669_Q	0.613	0.58
635_L	638_M	0.611	0.57
398_L	402_S	0.610	0.57
534_I	650_I	0.609	0.57
95_I	133_I	0.609	0.57
254_L	257_A	0.608	0.57
487_A	536_D	0.608	0.57
138_L	160_I	0.606	0.57
555_L	562_Q	0.606	0.57
7_E	84_H	0.606	0.57
597_L	610_F	0.604	0.57
605_I	609_F	0.603	0.56
207_I	210_Q	0.603	0.56
46_P	50_T	0.603	0.56
350_I	388_F	0.603	0.56
33_S	322_S	0.602	0.56
364_I	394_A	0.602	0.56
35_R	38_H	0.602	0.56
27_A	62_G	0.601	0.56
247_E	251_L	0.601	0.56
147_G	428_M	0.601	0.56
588_L	593_T	0.601	0.56
254_L	291_R	0.601	0.56
196_V	200_E	0.599	0.56
590_I	629_L	0.599	0.56
35_R	58_Q	0.599	0.56
198_K	201_L	0.598	0.56
554_M	669_Q	0.598	0.56
417_V	426_S	0.597	0.56
633_R	676_L	0.597	0.56
270_L	282_E	0.597	0.56
561_Q	564_K	0.596	0.56
592_G	629_L	0.596	0.56
289_H	354_I	0.595	0.55
77_T	554_M	0.593	0.55
360_M	395_F	0.593	0.55
618_P	630_R	0.593	0.55
220_S	223_S	0.591	0.55
300_E	634_I	0.590	0.55
461_M	490_V	0.590	0.55
291_R	352_E	0.590	0.55
57_K	62_G	0.589	0.55
122_V	212_K	0.588	0.55
165_I	203_K	0.587	0.54
107_K	145_G	0.587	0.54
108_L	122_V	0.586	0.54
318_I	322_S	0.585	0.54
122_V	680_L	0.584	0.54
260_Y	264_L	0.584	0.54
126_L	148_I	0.583	0.54
586_G	651_L	0.583	0.54
328_D	332_N	0.583	0.54
139_T	362_E	0.583	0.54
414_K	460_D	0.581	0.54
612_M	635_L	0.581	0.54
239_K	275_G	0.581	0.54
55_L	58_Q	0.580	0.54
420_S	448_L	0.579	0.53
546_L	549_N	0.579	0.53
376_E	586_G	0.579	0.53
343_L	361_K	0.577	0.53
448_L	466_V	0.576	0.53
162_G	289_H	0.576	0.53
271_E	274_F	0.575	0.53
334_S	338_G	0.575	0.53
279_P	288_I	0.575	0.53
267_A	274_F	0.574	0.53
208_L	657_A	0.573	0.53
559_L	582_R	0.573	0.53
648_S	651_L	0.573	0.53
144_R	415_A	0.572	0.53
86_Y	90_E	0.571	0.52
6_R	10_L	0.571	0.52
98_S	111_L	0.571	0.52
27_A	294_N	0.571	0.52
547_K	550_P	0.570	0.52
154_E	241_G	0.569	0.52
140_L	655_S	0.568	0.52
639_A	648_S	0.567	0.52
476_I	490_V	0.567	0.52
394_A	397_V	0.565	0.52
35_R	63_L	0.565	0.52
342_H	392_E	0.564	0.52
575_A	601_K	0.564	0.52
3_M	47_L	0.564	0.52
638_M	655_S	0.563	0.51
204_M	207_I	0.563	0.51
378_G	610_F	0.563	0.51
606_V	609_F	0.562	0.51
268_G	318_I	0.562	0.51
581_E	588_L	0.561	0.51
401_G	420_S	0.560	0.51
379_V	397_V	0.560	0.51
77_T	309_E	0.560	0.51
582_R	598_Y	0.559	0.51
583_E	621_V	0.559	0.51
160_I	164_L	0.558	0.51
83_Q	247_E	0.558	0.51
402_S	442_S	0.558	0.51
98_S	115_L	0.558	0.51
621_V	640_P	0.555	0.50
317_L	379_V	0.554	0.50
437_L	463_V	0.554	0.50
222_S	226_A	0.553	0.50
427_K	445_M	0.553	0.50
633_R	638_M	0.552	0.50
443_F	459_Y	0.552	0.50
578_C	586_G	0.552	0.50
147_G	285_Y	0.551	0.50
434_K	443_F	0.551	0.50
57_K	263_A	0.551	0.50
327_M	404_L	0.551	0.50
564_K	576_A	0.551	0.50
598_Y	633_R	0.551	0.50
442_S	463_V	0.550	0.50
434_K	484_E	0.550	0.50
140_L	441_E	0.550	0.50
450_E	453_G	0.549	0.50
65_A	634_I	0.547	0.49
230_H	395_F	0.546	0.49
429_L	478_V	0.546	0.49
63_L	673_G	0.546	0.49
39_R	42_K	0.546	0.49
316_R	319_A	0.545	0.49
107_K	438_P	0.545	0.49
359_P	394_A	0.545	0.49
603_D	641_G	0.545	0.49
359_P	422_G	0.545	0.49
196_V	201_L	0.545	0.49
220_S	346_A	0.544	0.49
582_R	621_V	0.544	0.49
206_R	210_Q	0.544	0.49
35_R	257_A	0.544	0.49
555_L	598_Y	0.543	0.49
230_H	279_P	0.543	0.49
127_D	285_Y	0.543	0.49
241_G	282_E	0.543	0.49
346_A	676_L	0.541	0.49
266_I	414_K	0.539	0.48
106_V	353_N	0.539	0.48
433_L	490_V	0.539	0.48
356_I	396_I	0.539	0.48
574_K	604_E	0.538	0.48
324_K	378_G	0.538	0.48
154_E	157_K	0.537	0.48
368_Y	432_R	0.537	0.48
546_L	606_V	0.537	0.48
292_S	354_I	0.536	0.48
480_P	483_N	0.536	0.48
559_L	621_V	0.534	0.48
263_A	286_I	0.533	0.48
259_E	290_L	0.532	0.47
589_G	629_L	0.531	0.47
365_K	394_A	0.531	0.47
598_Y	638_M	0.531	0.47
590_I	621_V	0.530	0.47
383_F	386_M	0.529	0.47
622_D	629_L	0.529	0.47
261_S	264_L	0.529	0.47
267_A	284_G	0.528	0.47
205_E	316_R	0.528	0.47
140_L	389_S	0.527	0.47
52_G	114_D	0.527	0.47
4_T	598_Y	0.526	0.47
608_P	646_E	0.526	0.47
575_A	636_V	0.526	0.47
548_T	669_Q	0.526	0.47
577_V	580_A	0.525	0.47
7_E	420_S	0.525	0.47
400_F	459_Y	0.525	0.47
92_K	115_L	0.525	0.47
653_A	680_L	0.525	0.47
322_S	329_L	0.524	0.46
236_E	239_K	0.524	0.46
554_M	558_E	0.524	0.46
310_T	383_F	0.524	0.46
432_R	482_L	0.524	0.46
588_L	647_G	0.523	0.46
401_G	423_I	0.523	0.46
9_K	13_H	0.523	0.46
119_N	638_M	0.522	0.46
264_L	314_T	0.521	0.46
579_L	610_F	0.521	0.46
291_R	462_I	0.521	0.46
552_H	580_A	0.520	0.46
11_L	136_F	0.519	0.46
285_Y	440_I	0.519	0.46
355_E	378_G	0.519	0.46
288_I	494_I	0.519	0.46
10_L	336_Y	0.518	0.46
294_N	427_K	0.518	0.46
266_I	347_V	0.518	0.46
574_K	654_I	0.518	0.46
602_N	605_I	0.518	0.46
423_I	426_S	0.517	0.46
650_I	653_A	0.517	0.46
555_L	650_I	0.517	0.46
560_F	575_A	0.517	0.46
364_I	397_V	0.516	0.45
21_I	316_R	0.515	0.45
204_M	270_L	0.515	0.45
663_E	679_R	0.515	0.45
33_S	62_G	0.515	0.45
279_P	286_I	0.514	0.45
106_V	114_D	0.514	0.45
465_T	480_P	0.514	0.45
244_I	263_A	0.513	0.45
127_D	142_R	0.513	0.45
349_R	394_A	0.513	0.45
132_W	136_F	0.513	0.45
493_Y	496_R	0.512	0.45
641_G	647_G	0.512	0.45
635_L	657_A	0.512	0.45
639_A	647_G	0.511	0.45
129_L	150_L	0.511	0.45
96_L	318_I	0.511	0.45
99_L	150_L	0.511	0.45
345_P	356_I	0.511	0.45
371_L	374_A	0.511	0.45
213_E	216_A	0.510	0.45
266_I	561_Q	0.510	0.45
107_K	345_P	0.510	0.45
563_L	598_Y	0.510	0.45
573_E	662_G	0.509	0.45
621_V	636_V	0.508	0.44
589_G	622_D	0.507	0.44
23_V	38_H	0.506	0.44
575_A	586_G	0.506	0.44
147_G	419_C	0.505	0.44
208_L	418_V	0.505	0.44
251_L	255_M	0.504	0.44
617_T	632_T	0.504	0.44
652_S	655_S	0.503	0.44
590_I	655_S	0.503	0.44
478_V	486_D	0.502	0.44
534_I	664_S	0.502	0.44
281_A	284_G	0.502	0.44
338_G	401_G	0.502	0.44
160_I	294_N	0.501	0.44
282_E	364_I	0.501	0.44
552_H	578_C	0.501	0.44
57_K	438_P	0.501	0.44
598_Y	621_V	0.501	0.44
237_R	463_V	0.500	0.43
45_K	605_I	0.500	0.43
542_T	610_F	0.500	0.43

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4r6iA	2	0.6542	100	0.47	Contact Map
3sqnA	2	0.6499	100	0.52	Contact Map
1h99A	2	0.3127	100	0.778	Contact Map
1a6jA	4	0.2233	100	0.8	Contact Map
3urrA	2	0.219	100	0.804	Contact Map
3oxpA	2	0.2104	100	0.804	Contact Map
2a0jA	1	0.2104	100	0.805	Contact Map
1a3aA	2	0.2061	100	0.81	Contact Map
2oq3A	1	0.2089	100	0.81	Contact Map
4m62S	1	0.2147	100	0.811	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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