YWQA - BACSU - GREMLIN Contacts

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YWQA - Uncharacterized ATP-dependent helicase YwqA

UniProt:	P94593	Sequences: MASLKEILIHVEQMEDGSFTLSAFDENEQPLPYSHMKKHLFQWHESSFYGTFLEDVSFIGTTAVLLSPWMTVELLGKNSFNSFSSVQLTEETEPLIEAASTIYEFIADGDFMPDYDAWTNGVFRWKDRDNILEGFTAEWFSAAVQDYIQYDDDLREKWEHIKEKSPAVTTFRGHFLDEEDFLEGIGWIDDQSPFTVGLRLNEPDFDGDEWKIEMFLRDKKSGAVEFFDGLKSLKKSWQAYSDKIAREQDRFHRTVPWLSFDSGTTLISEEEAWIFLSEASETLVDMGVEILLPSWWQIVRDSNMMLKAKVSSSPRGESFVGMNALLDFNWRFATNGIELTEAEFNELVASNRRLVNIRGQWVKIDPQFIKQMKRLMEKAESEGLHMSDILARELMDQQDGGLEDSDLIDTSAFAGIQFDLSKQLRSLIRKLTAAENLPEHKVSPSFKGTLRPYQKYGMNWLLFLRESGFGACLADDMGLGKTIQMIAYFLHVKESGRQKTPHLIIAPTSVLGNWQRELQTFAPDLSVALHYGPRRPKGDDFAAHYENADVVLTSYGLSHADTEELSSVTWNTICLDEAQNIKNAHTKQSRAIRKLKGLHHIALSGTPMENRLTELWSIFDFMNKGYLGSLTGFHKRYVLPIEKDRDEKRIGQLQQLIRPFLLRRTKRDEEVALNLPEKLEEKEFIPLSAEQASLYEQLVKDTFDHMTSLTGMQRKALILSMLGRLKQICDHPALYLKEEQTELLAGRSVKLEKLLELMTAIRAQNESCLIFTQYIQMGNMMKRLLEKTFGEPVQFLNGSLSKQERDTLVEKFQRKEYPTLILSLKAGGTGLNLTAANHVIHYDRWWNPAVENQATDRAYRIGQERFVHVHKMITTGTIEEKIDVMLESKQTLNDQIIQSENWITELSTQELEELFTLSATAQ	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	922 (763)
Sequences:	2094 (1560)
Seq/√Len:	56.5

ECOLI - RAPA
BACSU - YWQA
HALSA - O52003
SULSO - Q97XQ7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
335_N	338_E	3.635	1.00
766_E	837_N	3.567	1.00
518_L	550_V	3.331	1.00
268_S	271_E	3.210	1.00
366_P	369_I	3.057	1.00
278_E	281_E	2.878	1.00
370_K	374_R	2.854	1.00
369_I	374_R	2.849	1.00
893_N	898_Q	2.722	1.00
240_Y	243_K	2.712	1.00
366_P	371_Q	2.622	1.00
271_E	276_L	2.560	1.00
326_L	332_F	2.539	1.00
540_D	544_H	2.515	1.00
755_L	789_F	2.495	1.00
327_D	332_F	2.455	1.00
372_M	375_L	2.427	1.00
351_N	358_R	2.397	1.00
294_S	297_Q	2.389	1.00
389_I	392_R	2.373	1.00
256_P	260_F	2.369	1.00
351_N	354_L	2.354	1.00
530_H	561_D	2.343	1.00
687_L	877_T	2.333	1.00
165_S	168_V	2.318	1.00
160_H	163_E	2.314	1.00
464_L	471_A	2.296	1.00
355_V	358_R	2.292	1.00
327_D	330_W	2.283	1.00
578_A	602_A	2.277	1.00
324_A	327_D	2.264	1.00
219_K	222_G	2.234	1.00
369_I	372_M	2.226	1.00
762_R	818_P	2.204	1.00
457_G	484_Q	2.189	1.00
287_G	292_L	2.189	1.00
287_G	290_I	2.188	1.00
368_F	371_Q	2.162	1.00
250_R	253_R	2.161	1.00
321_G	326_L	2.160	1.00
269_E	272_A	2.145	1.00
237_W	240_Y	2.142	1.00
164_K	167_A	2.107	1.00
326_L	333_A	2.060	1.00
419_D	422_K	2.056	1.00
255_V	258_L	2.049	1.00
371_Q	376_M	2.045	1.00
258_L	261_D	2.037	1.00
328_F	332_F	2.031	1.00
768_C	818_P	2.031	1.00
540_D	545_Y	2.029	1.00
277_S	282_T	2.026	1.00
813_Q	835_A	2.018	1.00
218_D	221_S	2.006	1.00
299_V	302_S	1.988	1.00
273_W	277_S	1.978	1.00
427_L	430_K	1.975	1.00
321_G	327_D	1.970	1.00
292_L	295_W	1.969	1.00
238_Q	242_D	1.964	1.00
556_G	580_N	1.956	1.00
388_D	392_R	1.944	1.00
244_I	248_Q	1.933	1.00
257_W	260_F	1.928	1.00
785_L	819_T	1.921	1.00
211_K	215_F	1.906	1.00
190_D	195_T	1.904	1.00
243_K	248_Q	1.903	1.00
391_A	395_M	1.890	1.00
340_T	343_E	1.870	1.00
235_K	238_Q	1.868	1.00
192_S	195_T	1.865	1.00
273_W	276_L	1.837	0.99
279_A	282_T	1.829	0.99
279_A	283_L	1.829	0.99
352_R	356_N	1.824	0.99
268_S	272_A	1.811	0.99
270_E	273_W	1.809	0.99
395_M	402_L	1.807	0.99
351_N	355_V	1.804	0.99
392_R	397_Q	1.802	0.99
285_D	290_I	1.798	0.99
221_S	225_E	1.797	0.99
329_N	332_F	1.793	0.99
490_L	522_A	1.791	0.99
188_I	191_Q	1.788	0.99
324_A	332_F	1.788	0.99
240_Y	245_A	1.785	0.99
365_D	368_F	1.784	0.99
181_F	184_G	1.782	0.99
208_D	211_K	1.776	0.99
541_F	544_H	1.776	0.99
874_T	877_T	1.774	0.99
295_W	298_I	1.760	0.99
151_D	155_R	1.760	0.99
222_G	225_E	1.759	0.99
217_R	220_K	1.744	0.99
248_Q	251_F	1.741	0.99
276_L	279_A	1.739	0.99
369_I	373_K	1.737	0.99
483_I	486_I	1.734	0.99
233_L	236_S	1.728	0.99
327_D	335_N	1.727	0.99
221_S	224_V	1.726	0.99
376_M	379_A	1.721	0.99
324_A	328_F	1.716	0.99
284_V	287_G	1.715	0.99
297_Q	300_R	1.712	0.99
198_L	204_D	1.711	0.99
180_D	185_I	1.706	0.99
208_D	213_E	1.702	0.99
235_K	240_Y	1.693	0.99
327_D	333_A	1.691	0.99
686_P	875_T	1.689	0.99
758_M	768_C	1.689	0.99
240_Y	244_I	1.687	0.99
371_Q	374_R	1.686	0.99
370_K	376_M	1.675	0.99
271_E	274_I	1.672	0.99
193_P	196_V	1.669	0.99
516_R	810_E	1.667	0.99
281_E	285_D	1.666	0.99
219_K	225_E	1.661	0.99
245_A	253_R	1.654	0.99
276_L	280_S	1.651	0.99
274_I	278_E	1.651	0.99
575_L	581_I	1.647	0.99
191_Q	194_F	1.635	0.99
462_L	491_H	1.633	0.99
289_E	294_S	1.632	0.99
354_L	357_I	1.631	0.99
152_D	155_R	1.629	0.99
233_L	237_W	1.622	0.99
254_T	257_W	1.619	0.99
246_R	249_D	1.617	0.99
369_I	376_M	1.617	0.99
298_I	301_D	1.616	0.99
541_F	545_Y	1.605	0.99
203_P	206_D	1.599	0.98
755_L	784_L	1.583	0.98
222_G	226_F	1.583	0.98
328_F	333_A	1.582	0.98
247_E	252_H	1.582	0.98
246_R	250_R	1.571	0.98
277_S	281_E	1.565	0.98
320_V	327_D	1.556	0.98
540_D	543_A	1.552	0.98
181_F	185_I	1.550	0.98
157_K	161_I	1.545	0.98
420_L	423_Q	1.544	0.98
374_R	377_E	1.540	0.98
185_I	188_I	1.539	0.98
844_R	886_L	1.534	0.98
199_R	224_V	1.530	0.98
218_D	222_G	1.530	0.98
151_D	154_L	1.527	0.98
179_E	182_L	1.523	0.98
201_N	210_W	1.517	0.98
278_E	282_T	1.516	0.98
320_V	326_L	1.510	0.98
275_F	278_E	1.504	0.98
318_S	321_G	1.501	0.98
219_K	226_F	1.491	0.98
169_T	172_R	1.490	0.98
153_D	156_E	1.481	0.97
281_E	284_V	1.480	0.97
251_F	255_V	1.470	0.97
318_S	332_F	1.468	0.97
274_I	279_A	1.466	0.97
254_T	261_D	1.465	0.97
423_Q	429_R	1.464	0.97
753_K	756_E	1.463	0.97
175_F	178_E	1.462	0.97
329_N	333_A	1.457	0.97
178_E	182_L	1.454	0.97
191_Q	198_L	1.453	0.97
272_A	289_E	1.453	0.97
268_S	280_S	1.452	0.97
239_A	251_F	1.450	0.97
388_D	391_A	1.447	0.97
417_Q	420_L	1.443	0.97
232_S	235_K	1.440	0.97
149_Q	155_R	1.437	0.97
290_I	293_P	1.434	0.97
247_E	250_R	1.433	0.97
400_G	403_E	1.427	0.97
282_T	285_D	1.424	0.97
328_F	335_N	1.420	0.97
298_I	302_S	1.420	0.97
156_E	160_H	1.417	0.97
234_K	237_W	1.409	0.97
180_D	183_E	1.407	0.97
152_D	156_E	1.400	0.96
766_E	838_H	1.395	0.96
283_L	291_L	1.388	0.96
290_I	300_R	1.384	0.96
320_V	332_F	1.378	0.96
283_L	289_E	1.370	0.96
359_G	362_V	1.368	0.96
362_V	366_P	1.367	0.96
242_D	246_R	1.364	0.96
370_K	375_L	1.364	0.96
328_F	331_R	1.357	0.96
194_F	197_G	1.355	0.96
237_W	241_S	1.353	0.96
196_V	200_L	1.350	0.96
423_Q	428_I	1.350	0.96
155_R	158_W	1.347	0.96
367_Q	373_K	1.346	0.96
243_K	246_R	1.345	0.96
184_G	188_I	1.343	0.95
196_V	201_N	1.342	0.95
322_M	329_N	1.341	0.95
287_G	294_S	1.341	0.95
190_D	198_L	1.331	0.95
760_A	764_Q	1.330	0.95
227_F	230_L	1.330	0.95
683_E	890_Q	1.328	0.95
189_D	192_S	1.326	0.95
239_A	246_R	1.324	0.95
217_R	223_A	1.324	0.95
277_S	280_S	1.323	0.95
281_E	288_V	1.320	0.95
320_V	324_A	1.319	0.95
206_D	220_K	1.318	0.95
218_D	223_A	1.318	0.95
244_I	249_D	1.317	0.95
236_S	239_A	1.315	0.95
367_Q	371_Q	1.312	0.95
322_M	325_L	1.310	0.95
321_G	332_F	1.308	0.95
230_L	233_L	1.306	0.95
272_A	277_S	1.304	0.95
347_L	350_S	1.302	0.95
244_I	247_E	1.300	0.95
367_Q	374_R	1.298	0.95
332_F	338_E	1.297	0.95
205_F	208_D	1.293	0.94
182_L	186_G	1.291	0.94
257_W	261_D	1.291	0.94
234_K	238_Q	1.290	0.94
151_D	160_H	1.289	0.94
353_R	356_N	1.289	0.94
163_E	166_P	1.288	0.94
245_A	248_Q	1.287	0.94
154_L	159_E	1.285	0.94
275_F	279_A	1.285	0.94
287_G	298_I	1.282	0.94
195_T	201_N	1.282	0.94
391_A	401_G	1.281	0.94
155_R	160_H	1.281	0.94
443_S	446_F	1.279	0.94
249_D	253_R	1.278	0.94
218_D	226_F	1.276	0.94
273_W	280_S	1.276	0.94
261_D	264_T	1.275	0.94
283_L	293_P	1.272	0.94
289_E	292_L	1.270	0.94
662_L	666_K	1.270	0.94
236_S	240_Y	1.267	0.94
362_V	365_D	1.266	0.94
283_L	286_M	1.266	0.94
215_F	218_D	1.264	0.94
696_E	700_K	1.263	0.94
302_S	306_L	1.261	0.94
275_F	280_S	1.260	0.94
397_Q	401_G	1.253	0.93
162_K	168_V	1.251	0.93
395_M	403_E	1.235	0.93
243_K	249_D	1.233	0.93
428_I	431_L	1.230	0.93
323_N	326_L	1.229	0.93
427_L	431_L	1.229	0.93
308_A	311_S	1.226	0.93
166_P	170_T	1.222	0.93
238_Q	241_S	1.221	0.93
823_S	826_A	1.221	0.93
301_D	304_M	1.216	0.92
149_Q	152_D	1.216	0.92
151_D	157_K	1.214	0.92
294_S	300_R	1.210	0.92
391_A	394_L	1.209	0.92
318_S	329_N	1.201	0.92
779_N	795_F	1.200	0.92
207_G	212_I	1.200	0.92
366_P	374_R	1.199	0.92
285_D	288_V	1.197	0.92
392_R	402_L	1.196	0.92
616_W	633_F	1.194	0.92
354_L	358_R	1.194	0.92
280_S	283_L	1.194	0.92
515_Q	519_Q	1.192	0.92
284_V	289_E	1.191	0.92
260_F	263_G	1.187	0.91
220_K	224_V	1.187	0.91
266_L	269_E	1.186	0.91
219_K	224_V	1.185	0.91
291_L	294_S	1.185	0.91
191_Q	199_R	1.185	0.91
256_P	259_S	1.180	0.91
460_W	666_K	1.176	0.91
154_L	162_K	1.175	0.91
282_T	287_G	1.174	0.91
272_A	276_L	1.174	0.91
485_M	601_I	1.168	0.91
365_D	369_I	1.167	0.91
364_I	367_Q	1.166	0.91
159_E	162_K	1.165	0.91
324_A	338_E	1.165	0.91
168_V	173_G	1.162	0.91
244_I	251_F	1.162	0.91
374_R	379_A	1.161	0.91
165_S	171_F	1.160	0.90
187_W	193_P	1.159	0.90
369_I	375_L	1.158	0.90
392_R	395_M	1.156	0.90
397_Q	402_L	1.156	0.90
239_A	243_K	1.152	0.90
212_I	222_G	1.151	0.90
367_Q	372_M	1.151	0.90
392_R	401_G	1.147	0.90
622_M	688_S	1.146	0.90
248_Q	262_S	1.143	0.90
196_V	202_E	1.141	0.90
153_D	159_E	1.141	0.90
426_S	430_K	1.140	0.90
318_S	327_D	1.138	0.90
391_A	402_L	1.136	0.90
239_A	248_Q	1.136	0.90
192_S	201_N	1.135	0.89
395_M	398_Q	1.133	0.89
208_D	212_I	1.132	0.89
301_D	306_L	1.131	0.89
687_L	695_Y	1.125	0.89
197_G	201_N	1.122	0.89
190_D	194_F	1.119	0.89
272_A	283_L	1.119	0.89
310_V	313_S	1.117	0.89
267_I	271_E	1.116	0.89
352_R	355_V	1.115	0.89
234_K	240_Y	1.113	0.89
274_I	277_S	1.110	0.88
177_D	181_F	1.110	0.88
327_D	338_E	1.109	0.88
339_L	343_E	1.108	0.88
260_F	264_T	1.108	0.88
214_M	217_R	1.108	0.88
268_S	275_F	1.108	0.88
364_I	369_I	1.107	0.88
182_L	190_D	1.106	0.88
200_L	203_P	1.105	0.88
364_I	376_M	1.103	0.88
247_E	254_T	1.103	0.88
377_E	380_E	1.100	0.88
280_S	284_V	1.099	0.88
239_A	242_D	1.097	0.88
179_E	185_I	1.097	0.88
371_Q	375_L	1.097	0.88
322_M	330_W	1.094	0.88
220_K	223_A	1.093	0.88
227_F	240_Y	1.091	0.88
426_S	429_R	1.091	0.88
207_G	211_K	1.090	0.87
637_Y	829_T	1.090	0.87
791_E	818_P	1.088	0.87
293_P	297_Q	1.087	0.87
388_D	402_L	1.087	0.87
287_G	304_M	1.086	0.87
285_D	292_L	1.086	0.87
150_Y	153_D	1.084	0.87
311_S	314_P	1.083	0.87
308_A	312_S	1.082	0.87
233_L	240_Y	1.079	0.87
364_I	368_F	1.077	0.87
186_G	196_V	1.077	0.87
321_G	333_A	1.076	0.87
677_E	866_F	1.076	0.87
250_R	257_W	1.074	0.87
395_M	399_D	1.074	0.87
230_L	234_K	1.074	0.87
345_N	348_V	1.074	0.87
223_A	226_F	1.073	0.87
157_K	165_S	1.073	0.87
237_W	244_I	1.072	0.87
186_G	193_P	1.069	0.86
325_L	328_F	1.067	0.86
370_K	373_K	1.067	0.86
363_K	366_P	1.065	0.86
295_W	301_D	1.065	0.86
285_D	291_L	1.062	0.86
152_D	158_W	1.058	0.86
253_R	258_L	1.058	0.86
251_F	260_F	1.057	0.86
290_I	302_S	1.056	0.86
259_S	262_S	1.055	0.86
189_D	198_L	1.054	0.86
249_D	255_V	1.049	0.85
159_E	163_E	1.046	0.85
194_F	202_E	1.046	0.85
351_N	356_N	1.045	0.85
281_E	300_R	1.043	0.85
409_D	412_A	1.041	0.85
839_V	858_A	1.038	0.85
267_I	272_A	1.036	0.85
422_K	431_L	1.035	0.85
188_I	193_P	1.034	0.85
489_F	525_L	1.033	0.85
349_A	355_V	1.031	0.84
204_D	210_W	1.029	0.84
319_F	323_N	1.026	0.84
158_W	161_I	1.025	0.84
284_V	288_V	1.025	0.84
382_E	385_H	1.024	0.84
206_D	209_E	1.023	0.84
149_Q	156_E	1.021	0.84
157_K	164_K	1.020	0.84
181_F	197_G	1.015	0.83
217_R	222_G	1.015	0.83
338_E	343_E	1.015	0.83
542_A	545_Y	1.014	0.83
237_W	245_A	1.014	0.83
271_E	277_S	1.014	0.83
726_K	774_Y	1.012	0.83
281_E	286_M	1.011	0.83
384_L	387_S	1.011	0.83
366_P	378_K	1.011	0.83
190_D	196_V	1.007	0.83
251_F	254_T	1.006	0.83
272_A	280_S	1.005	0.83
159_E	164_K	1.004	0.83
190_D	193_P	1.003	0.83
150_Y	155_R	1.003	0.83
220_K	225_E	1.001	0.83
319_F	324_A	1.000	0.83
801_S	804_E	0.997	0.82
363_K	368_F	0.991	0.82
420_L	424_L	0.987	0.82
290_I	295_W	0.985	0.82
767_S	817_Y	0.984	0.82
328_F	338_E	0.984	0.82
187_W	198_L	0.982	0.81
290_I	298_I	0.980	0.81
363_K	367_Q	0.979	0.81
272_A	275_F	0.978	0.81
198_L	202_E	0.977	0.81
241_S	261_D	0.977	0.81
178_E	181_F	0.976	0.81
295_W	304_M	0.974	0.81
243_K	247_E	0.974	0.81
287_G	291_L	0.973	0.81
215_F	219_K	0.972	0.81
271_E	278_E	0.972	0.81
362_V	369_I	0.971	0.81
284_V	293_P	0.971	0.81
337_I	340_T	0.970	0.81
401_G	408_I	0.967	0.80
267_I	270_E	0.967	0.80
291_L	295_W	0.966	0.80
281_E	295_W	0.965	0.80
238_Q	247_E	0.963	0.80
815_K	826_A	0.963	0.80
293_P	296_W	0.963	0.80
232_S	236_S	0.962	0.80
249_D	254_T	0.961	0.80
423_Q	426_S	0.961	0.80
539_D	543_A	0.960	0.80
510_V	831_L	0.959	0.80
162_K	165_S	0.959	0.80
153_D	157_K	0.958	0.80
361_W	365_D	0.956	0.80
286_M	291_L	0.954	0.79
393_E	399_D	0.953	0.79
182_L	191_Q	0.951	0.79
168_V	172_R	0.949	0.79
294_S	298_I	0.948	0.79
323_N	327_D	0.947	0.79
257_W	262_S	0.946	0.79
284_V	291_L	0.946	0.79
185_I	190_D	0.946	0.79
189_D	194_F	0.945	0.79
274_I	280_S	0.945	0.79
197_G	200_L	0.945	0.79
179_E	184_G	0.944	0.79
405_S	409_D	0.944	0.79
282_T	303_N	0.944	0.79
366_P	370_K	0.944	0.79
336_G	340_T	0.943	0.79
177_D	186_G	0.936	0.78
418_F	427_L	0.935	0.78
232_S	244_I	0.934	0.78
288_V	292_L	0.933	0.78
201_N	204_D	0.933	0.78
181_F	188_I	0.931	0.78
260_F	265_T	0.931	0.78
418_F	425_R	0.930	0.78
293_P	299_V	0.929	0.78
270_E	293_P	0.928	0.78
324_A	333_A	0.928	0.78
243_K	256_P	0.926	0.77
236_S	246_R	0.926	0.77
240_Y	249_D	0.926	0.77
249_D	252_H	0.925	0.77
283_L	292_L	0.925	0.77
471_A	572_T	0.925	0.77
280_S	285_D	0.923	0.77
395_M	401_G	0.922	0.77
162_K	166_P	0.921	0.77
236_S	244_I	0.920	0.77
753_K	760_A	0.917	0.77
209_E	223_A	0.917	0.77
248_Q	264_T	0.917	0.77
327_D	331_R	0.913	0.76
241_S	250_R	0.911	0.76
475_D	662_L	0.910	0.76
285_D	293_P	0.908	0.76
569_T	596_K	0.908	0.76
191_Q	197_G	0.907	0.76
362_V	367_Q	0.907	0.76
158_W	163_E	0.907	0.76
319_F	327_D	0.906	0.76
772_T	778_G	0.906	0.76
243_K	257_W	0.904	0.76
158_W	162_K	0.904	0.76
372_M	376_M	0.904	0.76
175_F	187_W	0.904	0.76
442_V	446_F	0.904	0.76
387_S	390_L	0.902	0.76
214_M	224_V	0.902	0.76
180_D	184_G	0.901	0.75
477_M	827_G	0.900	0.75
268_S	276_L	0.898	0.75
282_T	288_V	0.898	0.75
154_L	157_K	0.898	0.75
249_D	258_L	0.897	0.75
315_R	321_G	0.896	0.75
326_L	338_E	0.893	0.75
276_L	281_E	0.893	0.75
425_R	428_I	0.892	0.75
287_G	303_N	0.891	0.75
154_L	158_W	0.890	0.75
149_Q	153_D	0.890	0.75
294_S	302_S	0.889	0.74
213_E	217_R	0.885	0.74
285_D	289_E	0.885	0.74
271_E	275_F	0.885	0.74
163_E	167_A	0.884	0.74
216_L	220_K	0.882	0.74
370_K	377_E	0.880	0.74
328_F	334_T	0.880	0.74
195_T	198_L	0.878	0.74
366_P	380_E	0.877	0.73
185_I	189_D	0.876	0.73
294_S	299_V	0.875	0.73
280_S	291_L	0.875	0.73
329_N	334_T	0.874	0.73
154_L	160_H	0.874	0.73
151_D	158_W	0.869	0.73
324_A	329_N	0.867	0.73
422_K	427_L	0.867	0.73
184_G	187_W	0.865	0.72
274_I	285_D	0.864	0.72
156_E	171_F	0.862	0.72
617_S	858_A	0.862	0.72
180_D	188_I	0.861	0.72
251_F	258_L	0.859	0.72
212_I	216_L	0.858	0.72
460_W	471_A	0.858	0.72
207_G	213_E	0.858	0.72
245_A	250_R	0.857	0.72
299_V	304_M	0.857	0.72
215_F	223_A	0.856	0.72
247_E	257_W	0.855	0.72
782_K	793_V	0.854	0.71
195_T	199_R	0.854	0.71
219_K	223_A	0.853	0.71
150_Y	160_H	0.852	0.71
198_L	203_P	0.852	0.71
295_W	299_V	0.851	0.71
288_V	294_S	0.849	0.71
339_L	351_N	0.846	0.71
175_F	186_G	0.845	0.71
170_T	173_G	0.844	0.71
388_D	395_M	0.843	0.70
701_D	869_V	0.843	0.70
398_Q	402_L	0.841	0.70
177_D	182_L	0.839	0.70
287_G	293_P	0.839	0.70
874_T	883_D	0.838	0.70
236_S	242_D	0.838	0.70
241_S	248_Q	0.838	0.70
324_A	335_N	0.838	0.70
186_G	194_F	0.837	0.70
221_S	226_F	0.833	0.70
511_L	552_L	0.832	0.69
493_K	525_L	0.831	0.69
342_A	345_N	0.831	0.69
720_S	723_G	0.830	0.69
248_Q	252_H	0.829	0.69
183_E	187_W	0.828	0.69
163_E	168_V	0.827	0.69
368_F	374_R	0.825	0.69
399_D	402_L	0.824	0.69
720_S	724_R	0.824	0.69
241_S	246_R	0.824	0.69
246_R	265_T	0.823	0.69
326_L	329_N	0.823	0.69
157_K	160_H	0.823	0.69
274_I	289_E	0.822	0.69
150_Y	156_E	0.821	0.68
451_R	672_A	0.821	0.68
167_A	172_R	0.821	0.68
794_Q	811_K	0.820	0.68
206_D	210_W	0.819	0.68
388_D	398_Q	0.818	0.68
215_F	224_V	0.816	0.68
404_D	408_I	0.815	0.68
204_D	208_D	0.814	0.68
389_I	402_L	0.813	0.68
269_E	283_L	0.812	0.68
252_H	255_V	0.811	0.67
247_E	262_S	0.809	0.67
461_L	488_Y	0.809	0.67
372_M	380_E	0.809	0.67
326_L	330_W	0.805	0.67
245_A	252_H	0.803	0.67
166_P	169_T	0.803	0.67
255_V	259_S	0.802	0.67
286_M	289_E	0.802	0.67
394_L	399_D	0.801	0.67
256_P	263_G	0.801	0.67
244_I	252_H	0.800	0.66
245_A	249_D	0.800	0.66
794_Q	817_Y	0.799	0.66
269_E	274_I	0.797	0.66
200_L	205_F	0.797	0.66
241_S	249_D	0.796	0.66
208_D	223_A	0.795	0.66
273_W	287_G	0.795	0.66
636_R	652_Q	0.794	0.66
390_L	403_E	0.794	0.66
319_F	329_N	0.793	0.66
150_Y	159_E	0.791	0.66
227_F	231_K	0.790	0.65
260_F	266_L	0.788	0.65
231_K	234_K	0.786	0.65
417_Q	425_R	0.785	0.65
300_R	303_N	0.784	0.65
344_F	351_N	0.781	0.65
352_R	358_R	0.780	0.64
178_E	185_I	0.780	0.64
286_M	296_W	0.779	0.64
366_P	376_M	0.779	0.64
258_L	262_S	0.778	0.64
353_R	357_I	0.778	0.64
152_D	171_F	0.777	0.64
175_F	179_E	0.776	0.64
362_V	370_K	0.775	0.64
296_W	299_V	0.774	0.64
184_G	193_P	0.774	0.64
202_E	208_D	0.773	0.64
212_I	224_V	0.773	0.64
767_S	837_N	0.772	0.64
233_L	246_R	0.771	0.64
175_F	181_F	0.770	0.63
493_K	549_D	0.770	0.63
295_W	302_S	0.769	0.63
421_S	430_K	0.768	0.63
330_W	333_A	0.768	0.63
254_T	265_T	0.768	0.63
325_L	333_A	0.766	0.63
269_E	273_W	0.766	0.63
283_L	295_W	0.766	0.63
188_I	194_F	0.766	0.63
193_P	198_L	0.765	0.63
194_F	198_L	0.765	0.63
158_W	164_K	0.764	0.63
385_H	393_E	0.763	0.63
206_D	218_D	0.763	0.63
340_T	354_L	0.763	0.63
373_K	378_K	0.762	0.63
277_S	302_S	0.761	0.63
216_L	223_A	0.761	0.63
277_S	284_V	0.760	0.62
319_F	330_W	0.759	0.62
361_W	366_P	0.758	0.62
491_H	496_G	0.758	0.62
160_H	170_T	0.757	0.62
774_Y	829_T	0.757	0.62
194_F	201_N	0.757	0.62
306_L	314_P	0.755	0.62
191_Q	201_N	0.755	0.62
239_A	254_T	0.754	0.62
871_K	886_L	0.754	0.62
333_A	336_G	0.751	0.61
579_Q	898_Q	0.751	0.61
187_W	213_E	0.751	0.61
320_V	329_N	0.751	0.61
421_S	426_S	0.750	0.61
150_Y	158_W	0.750	0.61
202_E	205_F	0.749	0.61
259_S	264_T	0.749	0.61
324_A	334_T	0.749	0.61
853_Q	860_R	0.748	0.61
279_A	289_E	0.745	0.61
188_I	195_T	0.745	0.61
391_A	398_Q	0.745	0.61
284_V	297_Q	0.744	0.61
353_R	358_R	0.744	0.61
199_R	205_F	0.743	0.61
897_I	900_E	0.743	0.61
213_E	216_L	0.743	0.61
293_P	305_M	0.741	0.60
401_G	412_A	0.740	0.60
152_D	157_K	0.740	0.60
154_L	170_T	0.740	0.60
360_Q	363_K	0.739	0.60
290_I	306_L	0.738	0.60
421_S	424_L	0.738	0.60
160_H	166_P	0.738	0.60
201_N	209_E	0.737	0.60
375_L	378_K	0.737	0.60
159_E	168_V	0.737	0.60
287_G	296_W	0.736	0.60
161_I	165_S	0.736	0.60
505_I	796_L	0.736	0.60
288_V	302_S	0.735	0.60
372_M	377_E	0.734	0.60
175_F	180_D	0.734	0.60
214_M	218_D	0.732	0.60
209_E	212_I	0.732	0.60
176_L	186_G	0.731	0.59
750_K	758_M	0.731	0.59
190_D	203_P	0.731	0.59
149_Q	162_K	0.730	0.59
289_E	293_P	0.729	0.59
199_R	202_E	0.728	0.59
337_I	344_F	0.727	0.59
394_L	401_G	0.726	0.59
265_T	268_S	0.726	0.59
809_V	831_L	0.723	0.59
189_D	199_R	0.723	0.59
218_D	224_V	0.723	0.59
285_D	295_W	0.722	0.58
338_E	344_F	0.721	0.58
240_Y	252_H	0.720	0.58
506_A	608_M	0.719	0.58
153_D	161_I	0.719	0.58
321_G	330_W	0.719	0.58
307_K	311_S	0.718	0.58
280_S	288_V	0.717	0.58
202_E	213_E	0.716	0.58
164_K	170_T	0.715	0.58
770_I	819_T	0.715	0.58
177_D	184_G	0.714	0.58
248_Q	258_L	0.714	0.58
382_E	386_M	0.712	0.57
296_W	302_S	0.712	0.57
513_N	517_E	0.711	0.57
319_F	326_L	0.711	0.57
231_K	235_K	0.710	0.57
845_W	851_E	0.709	0.57
177_D	180_D	0.708	0.57
244_I	250_R	0.706	0.57
883_D	886_L	0.704	0.57
244_I	256_P	0.704	0.57
251_F	264_T	0.703	0.56
315_R	330_W	0.702	0.56
824_L	854_A	0.701	0.56
193_P	200_L	0.701	0.56
149_Q	154_L	0.700	0.56
241_S	245_A	0.700	0.56
272_A	278_E	0.699	0.56
338_E	341_E	0.699	0.56
292_L	298_I	0.699	0.56
291_L	303_N	0.698	0.56
253_R	256_P	0.697	0.56
245_A	261_D	0.697	0.56
301_D	305_M	0.697	0.56
154_L	172_R	0.697	0.56
366_P	372_M	0.695	0.56
157_K	163_E	0.695	0.56
255_V	260_F	0.695	0.56
244_I	257_W	0.694	0.55
373_K	379_A	0.694	0.55
202_E	218_D	0.691	0.55
344_F	350_S	0.691	0.55
189_D	200_L	0.689	0.55
280_S	286_M	0.688	0.55
227_F	233_L	0.687	0.55
620_D	777_M	0.687	0.55
230_L	235_K	0.686	0.55
199_R	204_D	0.686	0.55
206_D	221_S	0.685	0.54
344_F	347_L	0.685	0.54
286_M	294_S	0.684	0.54
385_H	395_M	0.684	0.54
269_E	288_V	0.683	0.54
185_I	194_F	0.683	0.54
290_I	301_D	0.682	0.54
285_D	297_Q	0.682	0.54
330_W	334_T	0.681	0.54
347_L	353_R	0.681	0.54
336_G	351_N	0.680	0.54
236_S	243_K	0.679	0.54
156_E	161_I	0.679	0.54
253_R	259_S	0.678	0.54
192_S	200_L	0.678	0.54
204_D	211_K	0.677	0.54
149_Q	158_W	0.677	0.54
246_R	251_F	0.676	0.54
633_F	729_C	0.675	0.53
323_N	338_E	0.675	0.53
317_E	320_V	0.675	0.53
373_K	377_E	0.675	0.53
475_D	664_R	0.672	0.53
198_L	201_N	0.671	0.53
398_Q	405_S	0.670	0.53
189_D	196_V	0.670	0.53
164_K	169_T	0.669	0.53
281_E	290_I	0.669	0.53
241_S	247_E	0.668	0.53
271_E	284_V	0.668	0.53
781_M	842_Y	0.666	0.52
346_E	351_N	0.666	0.52
194_F	209_E	0.665	0.52
247_E	256_P	0.665	0.52
177_D	185_I	0.665	0.52
243_K	250_R	0.663	0.52
176_L	187_W	0.663	0.52
474_A	509_S	0.663	0.52
475_D	666_K	0.663	0.52
586_T	589_S	0.662	0.52
373_K	376_M	0.661	0.52
240_Y	248_Q	0.660	0.52
270_E	274_I	0.660	0.52
470_G	622_M	0.657	0.51
180_D	190_D	0.657	0.51
911_L	914_L	0.656	0.51
298_I	306_L	0.656	0.51
247_E	253_R	0.656	0.51
236_S	253_R	0.656	0.51
256_P	262_S	0.653	0.51
853_Q	857_R	0.653	0.51
423_Q	430_K	0.652	0.51
239_A	249_D	0.652	0.51
385_H	405_S	0.651	0.51
253_R	257_W	0.650	0.51
234_K	249_D	0.650	0.51
185_I	191_Q	0.650	0.51
382_E	387_S	0.649	0.51
203_P	212_I	0.648	0.50
159_E	166_P	0.648	0.50
419_D	423_Q	0.647	0.50
612_L	813_Q	0.647	0.50
392_R	400_G	0.645	0.50
193_P	199_R	0.645	0.50
767_S	818_P	0.644	0.50
211_K	226_F	0.644	0.50
149_Q	167_A	0.643	0.50
177_D	189_D	0.643	0.50
236_S	249_D	0.642	0.50
252_H	261_D	0.642	0.50
269_E	280_S	0.641	0.50
250_R	263_G	0.640	0.50
208_D	216_L	0.636	0.49
238_Q	245_A	0.636	0.49
367_Q	370_K	0.635	0.49
180_D	189_D	0.635	0.49
204_D	214_M	0.634	0.49
321_G	329_N	0.632	0.49
388_D	397_Q	0.631	0.49
211_K	222_G	0.631	0.49
282_T	286_M	0.630	0.49
190_D	197_G	0.629	0.48
288_V	300_R	0.629	0.48
347_L	351_N	0.629	0.48
277_S	306_L	0.628	0.48
209_E	214_M	0.627	0.48
202_E	207_G	0.627	0.48
193_P	201_N	0.627	0.48
277_S	283_L	0.627	0.48
194_F	214_M	0.627	0.48
253_R	260_F	0.625	0.48
155_R	161_I	0.625	0.48
249_D	256_P	0.625	0.48
302_S	305_M	0.624	0.48
362_V	368_F	0.624	0.48
211_K	216_L	0.623	0.48
181_F	192_S	0.623	0.48
383_G	387_S	0.622	0.48
207_G	218_D	0.622	0.48
291_L	298_I	0.622	0.48
186_G	190_D	0.622	0.48
279_A	285_D	0.622	0.48
253_R	261_D	0.622	0.48
611_R	831_L	0.621	0.48
476_D	666_K	0.620	0.47
554_S	654_Q	0.620	0.47
501_P	845_W	0.620	0.47
204_D	217_R	0.618	0.47
293_P	298_I	0.618	0.47
272_A	279_A	0.617	0.47
579_Q	829_T	0.617	0.47
194_F	200_L	0.616	0.47
272_A	286_M	0.616	0.47
365_D	374_R	0.616	0.47
368_F	375_L	0.616	0.47
620_D	627_L	0.615	0.47
276_L	282_T	0.615	0.47
316_G	321_G	0.615	0.47
165_S	173_G	0.613	0.47
195_T	200_L	0.612	0.47
268_S	277_S	0.612	0.47
232_S	241_S	0.612	0.47
150_Y	157_K	0.611	0.46
231_K	236_S	0.611	0.46
281_E	299_V	0.611	0.46
246_R	254_T	0.610	0.46
279_A	284_V	0.610	0.46
208_D	218_D	0.609	0.46
776_Q	779_N	0.609	0.46
258_L	263_G	0.609	0.46
849_A	893_N	0.608	0.46
194_F	199_R	0.607	0.46
275_F	295_W	0.607	0.46
371_Q	377_E	0.607	0.46
251_F	261_D	0.606	0.46
303_N	306_L	0.606	0.46
383_G	388_D	0.605	0.46
161_I	164_K	0.604	0.46
184_G	198_L	0.604	0.46
275_F	289_E	0.604	0.46
411_S	418_F	0.604	0.46
384_L	391_A	0.604	0.46
204_D	212_I	0.603	0.46
422_K	429_R	0.602	0.45
192_S	198_L	0.599	0.45
458_M	487_A	0.599	0.45
158_W	165_S	0.598	0.45
612_L	896_I	0.597	0.45
320_V	323_N	0.596	0.45
317_E	327_D	0.596	0.45
156_E	162_K	0.596	0.45
386_M	390_L	0.595	0.45
209_E	215_F	0.595	0.45
193_P	202_E	0.594	0.45
283_L	287_G	0.594	0.45
322_M	326_L	0.594	0.45
177_D	188_I	0.593	0.45
361_W	367_Q	0.592	0.44
296_W	305_M	0.591	0.44
271_E	289_E	0.591	0.44
153_D	160_H	0.591	0.44
275_F	284_V	0.591	0.44
768_C	840_I	0.589	0.44
333_A	338_E	0.589	0.44
181_F	190_D	0.587	0.44
283_L	294_S	0.587	0.44
424_L	428_I	0.587	0.44
453_Y	616_W	0.587	0.44
243_K	260_F	0.586	0.44
277_S	300_R	0.586	0.44
453_Y	671_V	0.585	0.44
241_S	251_F	0.585	0.44
267_I	273_W	0.584	0.44
204_D	227_F	0.584	0.44
155_R	164_K	0.584	0.44
265_T	291_L	0.583	0.43
282_T	294_S	0.582	0.43
382_E	395_M	0.582	0.43
389_I	403_E	0.581	0.43
271_E	282_T	0.581	0.43
390_L	402_L	0.580	0.43
186_G	203_P	0.580	0.43
735_Y	858_A	0.580	0.43
442_V	455_K	0.579	0.43
227_F	249_D	0.578	0.43
186_G	192_S	0.578	0.43
419_D	429_R	0.578	0.43
259_S	266_L	0.577	0.43
234_K	241_S	0.577	0.43
375_L	379_A	0.577	0.43
350_S	355_V	0.577	0.43
186_G	218_D	0.577	0.43
278_E	286_M	0.577	0.43
387_S	391_A	0.576	0.43
299_V	303_N	0.574	0.42
166_P	171_F	0.574	0.42
401_G	404_D	0.574	0.42
342_A	349_A	0.573	0.42
575_L	588_Q	0.573	0.42
259_S	280_S	0.572	0.42
237_W	243_K	0.571	0.42
336_G	349_A	0.571	0.42
323_N	328_F	0.570	0.42
288_V	296_W	0.570	0.42
475_D	553_T	0.569	0.42
270_E	277_S	0.569	0.42
402_L	407_L	0.567	0.42
296_W	301_D	0.567	0.42
325_L	335_N	0.566	0.42
288_V	299_V	0.566	0.42
209_E	213_E	0.565	0.42
269_E	278_E	0.565	0.42
184_G	216_L	0.565	0.42
235_K	244_I	0.564	0.41
372_M	384_L	0.564	0.41
891_T	894_D	0.564	0.41
238_Q	256_P	0.563	0.41
218_D	225_E	0.563	0.41
332_F	335_N	0.562	0.41
208_D	224_V	0.562	0.41
183_E	194_F	0.561	0.41
281_E	305_M	0.561	0.41
316_G	319_F	0.561	0.41
245_A	254_T	0.560	0.41
363_K	369_I	0.560	0.41
720_S	727_Q	0.560	0.41
289_E	298_I	0.559	0.41
425_R	430_K	0.559	0.41
176_L	180_D	0.559	0.41
199_R	208_D	0.559	0.41
155_R	167_A	0.559	0.41
368_F	373_K	0.558	0.41
554_S	722_L	0.558	0.41
844_R	849_A	0.557	0.41
300_R	304_M	0.556	0.41
321_G	325_L	0.556	0.41
391_A	397_Q	0.556	0.41
624_K	824_L	0.555	0.40
160_H	164_K	0.552	0.40
483_I	865_R	0.552	0.40
319_F	322_M	0.551	0.40
183_E	188_I	0.550	0.40
159_E	165_S	0.550	0.40
271_E	287_G	0.550	0.40
194_F	205_F	0.550	0.40
155_R	163_E	0.549	0.40
248_Q	254_T	0.549	0.40
271_E	279_A	0.549	0.40
156_E	167_A	0.549	0.40
828_G	832_N	0.549	0.40
152_D	164_K	0.549	0.40
313_S	316_G	0.548	0.40
179_E	183_E	0.548	0.40
364_I	370_K	0.547	0.40
194_F	203_P	0.547	0.40
555_Y	621_F	0.547	0.40
310_V	314_P	0.547	0.40
830_G	860_R	0.546	0.40
277_S	293_P	0.544	0.39
161_I	167_A	0.544	0.39
231_K	257_W	0.543	0.39
185_I	219_K	0.543	0.39
245_A	258_L	0.543	0.39
175_F	196_V	0.543	0.39
151_D	156_E	0.542	0.39
348_V	352_R	0.542	0.39
460_W	475_D	0.541	0.39
681_E	868_H	0.540	0.39
318_S	334_T	0.538	0.39
262_S	271_E	0.537	0.39
154_L	167_A	0.536	0.38
230_L	257_W	0.535	0.38
178_E	184_G	0.535	0.38
621_F	675_L	0.535	0.38
406_D	412_A	0.534	0.38
346_E	352_R	0.534	0.38
271_E	281_E	0.534	0.38
193_P	197_G	0.534	0.38
183_E	186_G	0.533	0.38
230_L	236_S	0.532	0.38
149_Q	161_I	0.532	0.38
167_A	171_F	0.532	0.38
175_F	185_I	0.531	0.38
193_P	215_F	0.531	0.38
286_M	298_I	0.531	0.38
280_S	299_V	0.530	0.38
251_F	263_G	0.529	0.38
254_T	262_S	0.529	0.38
425_R	429_R	0.529	0.38
402_L	412_A	0.528	0.38
324_A	341_E	0.528	0.38
234_K	246_R	0.528	0.38
323_N	329_N	0.527	0.38
287_G	295_W	0.525	0.37
276_L	296_W	0.525	0.37
249_D	264_T	0.525	0.37
508_T	556_G	0.525	0.37
318_S	326_L	0.525	0.37
195_T	204_D	0.524	0.37
242_D	247_E	0.524	0.37
362_V	371_Q	0.524	0.37
279_A	305_M	0.522	0.37
246_R	255_V	0.522	0.37
258_L	280_S	0.522	0.37
296_W	300_R	0.522	0.37
485_M	657_I	0.522	0.37
221_S	256_P	0.521	0.37
163_E	170_T	0.521	0.37
349_A	352_R	0.521	0.37
299_V	306_L	0.520	0.37
363_K	375_L	0.520	0.37
837_N	845_W	0.519	0.37
762_R	777_M	0.519	0.37
278_E	285_D	0.518	0.37
242_D	259_S	0.518	0.37
620_D	629_S	0.518	0.37
273_W	279_A	0.517	0.37
484_Q	827_G	0.517	0.37
476_D	845_W	0.516	0.36
278_E	293_P	0.515	0.36
273_W	285_D	0.514	0.36
189_D	197_G	0.514	0.36
191_Q	196_V	0.514	0.36
184_G	203_P	0.513	0.36
830_G	853_Q	0.513	0.36
238_Q	250_R	0.512	0.36
204_D	215_F	0.512	0.36
160_H	167_A	0.511	0.36
364_I	375_L	0.510	0.36
679_L	858_A	0.510	0.36
295_W	300_R	0.510	0.36
242_D	245_A	0.509	0.36
315_R	337_I	0.509	0.36
157_K	166_P	0.508	0.36
346_E	349_A	0.508	0.36
820_L	833_L	0.508	0.36
338_E	352_R	0.507	0.36
154_L	164_K	0.507	0.36
275_F	281_E	0.507	0.36
179_E	189_D	0.507	0.36
282_T	290_I	0.506	0.35
278_E	287_G	0.506	0.35
237_W	253_R	0.505	0.35
853_Q	889_K	0.504	0.35
198_L	205_F	0.504	0.35
912_E	916_T	0.503	0.35
441_K	495_S	0.503	0.35
475_D	570_W	0.502	0.35
858_A	911_L	0.502	0.35
415_G	419_D	0.502	0.35
420_L	429_R	0.501	0.35
151_D	168_V	0.500	0.35

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3mwyW	2	0.6421	100	0.433	Contact Map
1z3iX	4	0.5672	100	0.519	Contact Map
1z63A	1	0.5054	100	0.537	Contact Map
3dmqA	1	0.6312	100	0.671	Contact Map
2ykgA	1	0.461	100	0.682	Contact Map
4a2wA	1	0.6106	100	0.698	Contact Map
4a2qA	1	0.6063	100	0.701	Contact Map
1wp9A	1	0.4653	100	0.722	Contact Map
3hgtA	2	0.2408	100	0.729	Contact Map
1z5zA	1	0.2484	100	0.742	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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