ALLP - BACSU - GREMLIN Contacts

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ALLP - Probable allantoin permease

UniProt:	P94575	Sequences: MKLKESQQQSNRLSNEDLVPLGQEKRTWKAMNFASIWMGCIHNIPTYATVGGLIAIGLSPWQVLAIIITASLILFGALALNGHAGTKYGLPFPVIIRASYGIYGANIPALLRAFTAIMWLGIQTFAGSTALNILLLNMWPGWGEIGGEWNILGIHLSGLLSFVFFWAIHLLVLHHGMESIKRFEVWAGPLVYLVFGGMVWWAVDIAGGLGPIYSQPGKFHTFSETFWPFAAGVTGIIGIWATLILNIPDFTRFAETQKEQIKGQFYGLPGTFALFAFASITVTSGSQVAFGEPIWDVVDILARFDNPYVIVLSVITLCIATISVNVAANIVSPAYDIANALPKYINFKRGSFITALLALFTVPWKLMESATSVYAFLGLIGGMLGPVAGVMMADYFIIRKRELSVDDLYSETGRYVYWKGYNYRAFAATMLGALISLIGMYVPVLKSLYDISWFVGVLISFLFYIVLMRVHPPASLAIETVEHAQVRQAE	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	490 (428)
Sequences:	4815 (3062)
Seq/√Len:	148.0

ECOLI - ALLP CODB
BACSU - ALLP YXLA
SULSO - Q97X50 Q97WS4 Q97XP6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
393_A	461_F	6.979	1.00
404_S	407_D	6.972	1.00
393_A	465_I	5.940	1.00
431_L	463_F	4.500	1.00
85_G	248_P	4.287	1.00
23_Q	256_T	4.269	1.00
428_A	463_F	3.543	1.00
64_L	277_F	3.344	1.00
428_A	432_G	3.304	1.00
432_G	460_S	3.267	1.00
200_W	204_D	3.129	1.00
69_T	233_V	3.080	1.00
397_I	461_F	2.987	1.00
428_A	467_L	2.949	1.00
432_G	463_F	2.864	1.00
229_F	233_V	2.767	1.00
53_L	232_G	2.745	1.00
394_D	399_R	2.731	1.00
389_G	393_A	2.707	1.00
22_G	25_K	2.704	1.00
296_D	299_D	2.672	1.00
435_I	459_I	2.661	1.00
423_Y	427_A	2.643	1.00
390_V	429_T	2.554	1.00
59_S	62_Q	2.532	1.00
407_D	410_S	2.439	1.00
397_I	465_I	2.358	1.00
40_C	328_A	2.326	1.00
426_F	430_M	2.315	1.00
66_I	229_F	2.298	1.00
73_I	237_I	2.275	1.00
196_G	200_W	2.224	1.00
107_I	426_F	2.154	1.00
16_E	25_K	2.131	1.00
325_N	329_N	2.118	1.00
26_R	89_G	2.066	1.00
389_G	457_V	2.056	1.00
199_V	274_L	2.056	1.00
459_I	463_F	2.051	1.00
120_L	358_A	2.040	1.00
432_G	459_I	2.033	1.00
255_E	259_E	2.026	1.00
436_S	456_G	2.025	1.00
258_K	262_K	1.988	1.00
82_G	251_T	1.978	1.00
362_V	365_K	1.975	1.00
469_R	472_P	1.951	1.00
170_L	355_A	1.934	1.00
103_Y	106_N	1.934	1.00
53_L	63_V	1.919	1.00
463_F	467_L	1.895	1.00
166_W	359_L	1.887	1.00
98_A	403_L	1.861	1.00
124_T	169_H	1.851	1.00
404_S	414_R	1.838	1.00
160_L	164_F	1.834	1.00
454_F	458_L	1.834	1.00
346_N	349_R	1.830	1.00
120_L	325_N	1.829	1.00
84_A	95_I	1.817	1.00
60_P	64_L	1.808	1.00
119_W	122_I	1.802	1.00
465_I	469_R	1.800	1.00
127_G	165_F	1.796	1.00
462_L	466_V	1.785	1.00
63_V	280_I	1.775	1.00
16_E	19_V	1.743	1.00
167_A	171_L	1.707	1.00
389_G	460_S	1.697	1.00
427_A	467_L	1.696	1.00
182_R	185_V	1.692	1.00
175_H	179_S	1.688	1.00
99_S	394_D	1.665	1.00
30_A	259_E	1.664	1.00
163_V	167_A	1.662	1.00
62_Q	225_T	1.642	1.00
65_A	229_F	1.629	1.00
431_L	459_I	1.622	1.00
434_L	438_I	1.620	1.00
390_V	428_A	1.615	1.00
118_M	376_F	1.609	1.00
105_A	339_N	1.570	1.00
347_F	351_S	1.558	1.00
61_W	65_A	1.549	1.00
461_F	465_I	1.546	1.00
458_L	461_F	1.526	1.00
269_P	273_A	1.524	1.00
352_F	356_L	1.524	1.00
458_L	462_L	1.515	1.00
67_I	280_I	1.513	1.00
169_H	325_N	1.503	1.00
79_A	265_F	1.494	1.00
262_K	266_Y	1.492	1.00
100_Y	425_A	1.491	1.00
69_T	229_F	1.479	1.00
390_V	425_A	1.459	1.00
32_N	185_V	1.458	1.00
466_V	469_R	1.457	1.00
107_I	421_Y	1.445	1.00
193_L	197_G	1.438	1.00
95_I	248_P	1.435	1.00
421_Y	426_F	1.416	1.00
29_K	32_N	1.416	1.00
345_I	353_I	1.413	1.00
132_N	161_S	1.405	1.00
351_S	355_A	1.402	1.00
394_D	398_I	1.395	1.00
415_Y	420_G	1.370	1.00
128_S	161_S	1.370	1.00
425_A	428_A	1.367	1.00
67_I	276_A	1.366	1.00
199_V	278_A	1.352	1.00
76_G	80_L	1.345	1.00
410_S	413_G	1.337	1.00
354_T	358_A	1.328	1.00
425_A	464_Y	1.318	1.00
172_V	183_F	1.316	1.00
58_L	66_I	1.309	1.00
120_L	355_A	1.309	1.00
123_Q	329_N	1.304	1.00
85_G	251_T	1.304	1.00
129_T	296_D	1.292	1.00
430_M	434_L	1.289	1.00
87_K	257_Q	1.284	1.00
279_S	283_T	1.277	1.00
407_D	414_R	1.275	1.00
83_H	87_K	1.258	1.00
159_L	163_V	1.256	1.00
358_A	361_T	1.255	1.00
65_A	69_T	1.255	1.00
66_I	232_G	1.248	1.00
333_P	354_T	1.244	1.00
268_L	272_F	1.243	1.00
99_S	391_M	1.240	1.00
398_I	465_I	1.230	1.00
116_A	246_N	1.217	1.00
389_G	461_F	1.215	1.00
456_G	460_S	1.205	1.00
390_V	432_G	1.204	1.00
259_E	263_G	1.204	1.00
250_F	332_S	1.198	1.00
386_P	456_G	1.191	1.00
392_M	396_F	1.188	1.00
66_I	233_V	1.185	1.00
388_A	392_M	1.182	1.00
345_I	349_R	1.175	1.00
118_M	377_L	1.165	1.00
111_L	384_L	1.154	1.00
121_G	358_A	1.152	1.00
38_M	271_T	1.148	1.00
16_E	21_L	1.147	1.00
354_T	361_T	1.147	1.00
14_S	19_V	1.140	1.00
274_L	278_A	1.133	0.99
229_F	232_G	1.130	0.99
464_Y	468_M	1.130	0.99
355_A	358_A	1.128	0.99
253_F	335_Y	1.126	0.99
68_I	273_A	1.125	0.99
16_E	22_G	1.121	0.99
361_T	365_K	1.119	0.99
82_G	260_Q	1.115	0.99
134_L	311_V	1.107	0.99
80_L	396_F	1.103	0.99
466_V	470_V	1.103	0.99
81_N	391_M	1.100	0.99
273_A	277_F	1.096	0.99
70_A	236_I	1.079	0.99
226_F	230_A	1.077	0.99
97_R	105_A	1.074	0.99
424_R	467_L	1.070	0.99
365_K	368_E	1.069	0.99
100_Y	104_G	1.067	0.99
241_A	385_G	1.066	0.99
67_I	71_S	1.062	0.99
212_I	215_Q	1.060	0.99
424_R	468_M	1.059	0.99
71_S	276_A	1.058	0.99
123_Q	325_N	1.049	0.99
248_P	251_T	1.047	0.99
345_I	350_G	1.043	0.99
349_R	352_F	1.035	0.99
77_A	244_I	1.035	0.99
215_Q	284_S	1.034	0.99
75_F	79_A	1.034	0.99
134_L	314_V	1.024	0.99
439_G	455_V	1.019	0.99
435_I	455_V	1.017	0.99
84_A	88_Y	1.010	0.99
338_A	350_G	1.009	0.99
70_A	233_V	1.007	0.99
459_I	462_L	1.002	0.99
44_I	321_T	1.001	0.99
197_G	200_W	0.999	0.99
342_P	345_I	0.993	0.99
64_L	68_I	0.992	0.99
346_N	351_S	0.990	0.99
124_T	166_W	0.987	0.99
278_A	282_V	0.984	0.99
72_L	269_P	0.980	0.99
424_R	428_A	0.979	0.98
407_D	413_G	0.978	0.98
393_A	398_I	0.978	0.98
409_Y	415_Y	0.972	0.98
270_G	279_S	0.971	0.98
182_R	186_W	0.967	0.98
448_L	455_V	0.967	0.98
22_G	26_R	0.965	0.98
424_R	427_A	0.965	0.98
462_L	465_I	0.964	0.98
451_I	455_V	0.962	0.98
408_L	415_Y	0.959	0.98
66_I	70_A	0.958	0.98
299_D	303_R	0.958	0.98
281_T	285_G	0.955	0.98
98_A	408_L	0.954	0.98
33_F	251_T	0.954	0.98
92_F	248_P	0.953	0.98
433_A	436_S	0.950	0.98
272_F	276_A	0.949	0.98
353_I	357_L	0.944	0.98
51_G	126_A	0.938	0.98
189_P	192_Y	0.937	0.98
94_V	97_R	0.936	0.98
244_I	388_A	0.935	0.98
415_Y	422_N	0.935	0.98
74_L	240_W	0.928	0.98
256_T	259_E	0.924	0.98
88_Y	403_L	0.920	0.98
234_T	454_F	0.918	0.98
428_A	464_Y	0.917	0.98
332_S	336_D	0.915	0.98
294_I	300_I	0.913	0.98
128_S	132_N	0.912	0.98
422_N	468_M	0.910	0.98
198_M	304_F	0.909	0.98
134_L	315_I	0.908	0.98
42_H	191_V	0.906	0.98
83_H	396_F	0.906	0.98
262_K	265_F	0.903	0.97
103_Y	420_G	0.903	0.97
229_F	236_I	0.896	0.97
433_A	438_I	0.895	0.97
120_L	330_I	0.892	0.97
100_Y	108_P	0.892	0.97
197_G	201_W	0.890	0.97
121_G	361_T	0.889	0.97
119_W	377_L	0.889	0.97
75_F	269_P	0.887	0.97
62_Q	65_A	0.883	0.97
271_T	275_F	0.882	0.97
82_G	85_G	0.881	0.97
320_A	323_S	0.875	0.97
230_A	234_T	0.869	0.97
184_E	323_S	0.868	0.97
46_T	49_T	0.867	0.97
450_D	455_V	0.867	0.97
125_F	128_S	0.867	0.97
435_I	438_I	0.863	0.97
124_T	325_N	0.863	0.97
272_F	275_F	0.862	0.97
104_G	426_F	0.862	0.97
123_Q	321_T	0.860	0.97
102_I	411_E	0.858	0.97
202_A	206_A	0.858	0.97
203_V	281_T	0.858	0.97
73_I	233_V	0.858	0.97
100_Y	429_T	0.857	0.97
222_F	225_T	0.857	0.97
192_Y	196_G	0.857	0.97
197_G	309_V	0.857	0.97
422_N	425_A	0.857	0.97
360_F	400_K	0.854	0.96
173_L	351_S	0.853	0.96
71_S	239_I	0.852	0.96
84_A	391_M	0.850	0.96
233_V	237_I	0.845	0.96
18_L	94_V	0.840	0.96
300_I	304_F	0.838	0.96
127_G	321_T	0.837	0.96
67_I	273_A	0.836	0.96
431_L	438_I	0.835	0.96
37_W	93_P	0.835	0.96
320_A	324_V	0.832	0.96
300_I	303_R	0.831	0.96
461_F	464_Y	0.830	0.96
42_H	324_V	0.830	0.96
47_Y	282_V	0.830	0.96
346_N	350_G	0.827	0.96
202_A	282_V	0.826	0.96
196_G	431_L	0.822	0.96
113_A	337_I	0.822	0.96
111_L	380_I	0.822	0.96
427_A	431_L	0.819	0.95
97_R	339_N	0.817	0.95
92_F	332_S	0.815	0.95
34_A	38_M	0.814	0.95
430_M	433_A	0.813	0.95
242_T	384_L	0.813	0.95
445_L	448_L	0.809	0.95
254_A	257_Q	0.807	0.95
120_L	123_Q	0.806	0.95
81_N	247_I	0.805	0.95
468_M	471_H	0.805	0.95
178_E	182_R	0.802	0.95
44_I	47_Y	0.802	0.95
132_N	157_S	0.801	0.95
437_L	441_Y	0.796	0.95
394_D	468_M	0.794	0.95
265_F	269_P	0.792	0.95
199_V	282_V	0.792	0.95
45_P	321_T	0.790	0.95
283_T	286_S	0.786	0.94
83_H	401_R	0.785	0.94
191_V	324_V	0.785	0.94
68_I	164_F	0.783	0.94
277_F	281_T	0.780	0.94
397_I	400_K	0.779	0.94
261_I	265_F	0.776	0.94
81_N	392_M	0.774	0.94
135_L	138_M	0.774	0.94
34_A	266_Y	0.772	0.94
184_E	326_V	0.771	0.94
427_A	430_M	0.769	0.94
40_C	243_L	0.769	0.94
403_L	409_Y	0.767	0.94
326_V	330_I	0.767	0.94
159_L	363_P	0.767	0.94
397_I	401_R	0.766	0.94
266_Y	270_G	0.764	0.93
363_P	366_L	0.764	0.93
428_A	460_S	0.759	0.93
71_S	272_F	0.756	0.93
235_G	374_Y	0.754	0.93
333_P	336_D	0.748	0.93
14_S	331_V	0.747	0.93
423_Y	471_H	0.743	0.93
331_V	335_Y	0.742	0.92
110_L	340_A	0.742	0.92
75_F	321_T	0.740	0.92
160_L	163_V	0.739	0.92
45_P	128_S	0.738	0.92
177_M	253_F	0.738	0.92
423_Y	426_F	0.735	0.92
170_L	174_H	0.735	0.92
109_A	336_D	0.735	0.92
398_I	468_M	0.735	0.92
395_Y	398_I	0.735	0.92
86_T	260_Q	0.730	0.92
70_A	74_L	0.728	0.92
253_F	293_P	0.726	0.92
424_R	471_H	0.726	0.92
93_P	336_D	0.722	0.91
458_L	466_V	0.720	0.91
382_G	440_M	0.720	0.91
96_I	99_S	0.717	0.91
202_A	278_A	0.716	0.91
68_I	277_F	0.715	0.91
203_V	207_G	0.715	0.91
78_L	81_N	0.714	0.91
12_R	24_E	0.711	0.91
276_A	280_I	0.711	0.91
48_A	51_G	0.709	0.91
430_M	463_F	0.709	0.91
432_G	436_S	0.708	0.91
106_N	340_A	0.708	0.91
29_K	255_E	0.707	0.91
60_P	284_S	0.707	0.91
307_P	311_V	0.706	0.91
196_G	337_I	0.706	0.91
127_G	172_V	0.704	0.90
31_M	35_S	0.703	0.90
113_A	243_L	0.702	0.90
246_N	250_F	0.702	0.90
463_F	466_V	0.702	0.90
86_T	254_A	0.700	0.90
210_G	216_P	0.699	0.90
133_I	299_D	0.698	0.90
365_K	369_S	0.698	0.90
317_L	321_T	0.697	0.90
362_V	366_L	0.697	0.90
433_A	437_L	0.697	0.90
79_A	82_G	0.696	0.90
428_A	461_F	0.695	0.90
267_G	271_T	0.694	0.90
80_L	397_I	0.692	0.90
120_L	170_L	0.690	0.89
18_L	97_R	0.690	0.89
112_R	332_S	0.688	0.89
282_V	286_S	0.685	0.89
193_L	200_W	0.683	0.89
83_H	257_Q	0.682	0.89
173_L	355_A	0.681	0.89
90_L	95_I	0.680	0.89
90_L	94_V	0.680	0.89
300_I	383_M	0.678	0.89
157_S	160_L	0.677	0.89
411_E	414_R	0.676	0.89
128_S	158_G	0.676	0.89
452_S	456_G	0.675	0.88
135_L	352_F	0.673	0.88
455_V	458_L	0.672	0.88
63_V	67_I	0.672	0.88
51_G	283_T	0.671	0.88
354_T	357_L	0.668	0.88
40_C	321_T	0.667	0.88
408_L	414_R	0.667	0.88
52_G	55_A	0.666	0.88
344_Y	349_R	0.666	0.88
211_P	462_L	0.666	0.88
259_E	262_K	0.665	0.88
72_L	273_A	0.665	0.88
412_T	415_Y	0.664	0.88
172_V	326_V	0.663	0.88
125_F	129_T	0.661	0.87
43_N	46_T	0.661	0.87
240_W	268_L	0.659	0.87
99_S	390_V	0.658	0.87
41_I	272_F	0.655	0.87
174_H	352_F	0.655	0.87
183_F	323_S	0.655	0.87
225_T	230_A	0.655	0.87
282_V	301_L	0.653	0.87
435_I	444_V	0.652	0.87
252_R	331_V	0.652	0.87
413_G	420_G	0.652	0.87
40_C	240_W	0.652	0.87
361_T	366_L	0.651	0.87
78_L	242_T	0.651	0.87
236_I	239_I	0.651	0.87
393_A	397_I	0.650	0.87
97_R	394_D	0.648	0.86
337_I	350_G	0.647	0.86
96_I	105_A	0.646	0.86
50_V	279_S	0.644	0.86
118_M	380_I	0.641	0.86
169_H	322_I	0.641	0.86
172_V	322_I	0.641	0.86
19_V	25_K	0.639	0.86
27_T	178_E	0.638	0.86
62_Q	229_F	0.634	0.85
49_T	453_W	0.634	0.85
442_V	445_L	0.633	0.85
96_I	387_V	0.631	0.85
111_L	387_V	0.630	0.85
243_L	373_V	0.630	0.85
443_P	446_K	0.630	0.85
112_R	246_N	0.627	0.85
32_N	181_K	0.626	0.84
41_I	271_T	0.624	0.84
81_N	84_A	0.624	0.84
135_L	161_S	0.624	0.84
189_P	193_L	0.623	0.84
186_W	189_P	0.623	0.84
134_L	318_C	0.622	0.84
209_L	212_I	0.622	0.84
164_F	406_D	0.620	0.84
128_S	162_F	0.619	0.84
97_R	102_I	0.619	0.84
390_V	460_S	0.619	0.84
167_A	390_V	0.615	0.83
116_A	333_P	0.614	0.83
270_G	283_T	0.612	0.83
237_I	241_A	0.612	0.83
348_K	352_F	0.611	0.83
116_A	329_N	0.610	0.83
28_W	177_M	0.610	0.83
287_Q	432_G	0.609	0.83
459_I	468_M	0.609	0.83
366_L	369_S	0.609	0.83
41_I	93_P	0.608	0.83
190_L	316_T	0.607	0.83
107_I	430_M	0.604	0.82
191_V	320_A	0.603	0.82
28_W	254_A	0.602	0.82
354_T	366_L	0.602	0.82
58_L	62_Q	0.601	0.82
52_G	374_Y	0.600	0.82
212_I	281_T	0.600	0.82
334_A	339_N	0.600	0.82
431_L	434_L	0.598	0.82
466_V	471_H	0.598	0.82
127_G	180_I	0.595	0.81
30_A	263_G	0.595	0.81
50_V	53_L	0.595	0.81
319_I	323_S	0.595	0.81
224_E	228_P	0.594	0.81
237_I	457_V	0.593	0.81
59_S	217_G	0.592	0.81
169_H	172_V	0.591	0.81
103_Y	421_Y	0.591	0.81
287_Q	293_P	0.591	0.81
194_V	316_T	0.590	0.81
432_G	435_I	0.589	0.81
257_Q	315_I	0.589	0.81
121_G	125_F	0.588	0.81
212_I	266_Y	0.588	0.81
210_G	214_S	0.588	0.81
78_L	244_I	0.585	0.80
130_A	134_L	0.585	0.80
238_G	385_G	0.585	0.80
162_F	363_P	0.583	0.80
48_A	126_A	0.583	0.80
176_G	331_V	0.582	0.80
337_I	340_A	0.582	0.80
21_L	89_G	0.580	0.80
90_L	409_Y	0.580	0.80
53_L	236_I	0.578	0.79
71_S	115_T	0.576	0.79
240_W	244_I	0.576	0.79
24_E	462_L	0.575	0.79
74_L	78_L	0.575	0.79
243_L	328_A	0.575	0.79
450_D	453_W	0.575	0.79
120_L	169_H	0.574	0.79
227_W	231_A	0.573	0.79
386_P	432_G	0.573	0.79
240_W	272_F	0.571	0.79
207_G	211_P	0.570	0.79
282_V	300_I	0.570	0.79
432_G	456_G	0.570	0.79
68_I	258_K	0.569	0.78
297_V	301_L	0.568	0.78
266_Y	427_A	0.567	0.78
301_L	304_F	0.566	0.78
225_T	229_F	0.566	0.78
211_P	216_P	0.566	0.78
246_N	332_S	0.563	0.78
25_K	322_I	0.563	0.78
246_N	249_D	0.563	0.78
107_I	429_T	0.563	0.78
23_Q	213_Y	0.562	0.78
76_G	214_S	0.562	0.78
182_R	187_A	0.561	0.77
328_A	332_S	0.559	0.77
430_M	462_L	0.557	0.77
49_T	374_Y	0.557	0.77
213_Y	216_P	0.557	0.77
61_W	64_L	0.557	0.77
132_N	158_G	0.556	0.77
81_N	396_F	0.556	0.77
334_A	350_G	0.555	0.77
33_F	82_G	0.554	0.77
57_G	347_F	0.554	0.77
300_I	318_C	0.552	0.76
37_W	264_Q	0.551	0.76
229_F	426_F	0.550	0.76
86_T	257_Q	0.550	0.76
19_V	22_G	0.550	0.76
83_H	395_Y	0.549	0.76
22_G	253_F	0.548	0.76
93_P	339_N	0.547	0.76
275_F	279_S	0.546	0.76
173_L	330_I	0.546	0.76
51_G	85_G	0.546	0.76
223_S	270_G	0.544	0.75
446_K	449_Y	0.544	0.75
260_Q	264_Q	0.542	0.75
59_S	63_V	0.542	0.75
196_G	274_L	0.541	0.75
266_Y	269_P	0.540	0.75
20_P	88_Y	0.540	0.75
56_I	228_P	0.540	0.75
191_V	323_S	0.539	0.75
375_A	378_G	0.539	0.75
125_F	392_M	0.538	0.74
14_S	17_D	0.538	0.74
118_M	267_G	0.537	0.74
399_R	403_L	0.537	0.74
46_T	123_Q	0.537	0.74
26_R	255_E	0.536	0.74
212_I	277_F	0.535	0.74
73_I	103_Y	0.535	0.74
116_A	332_S	0.535	0.74
390_V	464_Y	0.534	0.74
160_L	311_V	0.534	0.74
27_T	181_K	0.534	0.74
45_P	122_I	0.534	0.74
98_A	415_Y	0.534	0.74
198_M	240_W	0.533	0.74
124_T	128_S	0.533	0.74
117_I	380_I	0.532	0.74
297_V	304_F	0.529	0.73
43_N	47_Y	0.529	0.73
314_V	323_S	0.529	0.73
385_G	389_G	0.529	0.73
165_F	322_I	0.529	0.73
46_T	239_I	0.528	0.73
15_N	346_N	0.528	0.73
134_L	214_S	0.528	0.73
129_T	299_D	0.528	0.73
279_S	286_S	0.527	0.73
403_L	408_L	0.527	0.73
195_F	320_A	0.527	0.73
284_S	288_V	0.526	0.73
232_G	236_I	0.526	0.73
443_P	447_S	0.525	0.73
13_L	17_D	0.524	0.73
160_L	200_W	0.522	0.72
130_A	298_V	0.520	0.72
393_A	464_Y	0.518	0.72
455_V	459_I	0.518	0.72
33_F	254_A	0.517	0.72
60_P	213_Y	0.517	0.72
123_Q	323_S	0.517	0.72
120_L	246_N	0.517	0.72
87_K	401_R	0.516	0.71
443_P	450_D	0.516	0.71
159_L	431_L	0.515	0.71
81_N	85_G	0.515	0.71
79_A	261_I	0.514	0.71
431_L	435_I	0.513	0.71
384_L	453_W	0.513	0.71
46_T	279_S	0.513	0.71
126_A	367_M	0.512	0.71
168_I	322_I	0.511	0.71
119_W	243_L	0.511	0.71
377_L	399_R	0.511	0.71
432_G	461_F	0.511	0.71
368_E	373_V	0.511	0.71
422_N	471_H	0.510	0.71
39_G	184_E	0.509	0.70
351_S	354_T	0.509	0.70
373_V	376_F	0.508	0.70
115_T	377_L	0.508	0.70
436_S	440_M	0.508	0.70
241_A	453_W	0.507	0.70
364_W	369_S	0.507	0.70
43_N	239_I	0.507	0.70
392_M	457_V	0.507	0.70
109_A	339_N	0.506	0.70
305_D	308_Y	0.506	0.70
321_T	383_M	0.506	0.70
295_W	304_F	0.504	0.70
160_L	424_R	0.504	0.70
341_L	458_L	0.503	0.69
383_M	433_A	0.503	0.69
234_T	437_L	0.502	0.69
37_W	44_I	0.501	0.69
189_P	389_G	0.501	0.69
360_F	364_W	0.500	0.69
210_G	213_Y	0.500	0.69

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2jlnA	1	0.9041	100	0.195	Contact Map
4djkA	2	0.8388	99.6	0.842	Contact Map
3l1lA	2	0.8224	99.5	0.854	Contact Map
3dh4A	3	0.849	99.5	0.857	Contact Map
3giaA	1	0.849	99.4	0.863	Contact Map
2xq2A	2	0.849	99.4	0.865	Contact Map
4wgvA	2	0.7388	98.5	0.904	Contact Map
4us3A	1	0.8245	97.8	0.92	Contact Map
4xp4A	1	0.9122	97.1	0.93	Contact Map
2a65A	2	0.9082	96.8	0.932	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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