GREMLIN Database
ARAB - Ribulokinase
UniProt: P94524 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 560 (478)
Sequences: 11899 (8101)
Seq/√Len: 370.5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
217_D233_D4.3041.00
131_H168_E3.9311.00
20_H25_E3.5751.00
16_A69_T3.3461.00
134_R168_E3.3261.00
20_H23_T3.1391.00
209_S212_A2.8981.00
424_R525_Y2.8911.00
106_L173_I2.8621.00
424_R428_E2.8321.00
149_R216_S2.8071.00
455_Q459_D2.7961.00
464_D512_T2.7911.00
431_K463_M2.7911.00
32_K72_S2.7201.00
399_L411_I2.7071.00
32_K68_T2.7001.00
194_S238_S2.6621.00
494_D498_K2.6291.00
42_V119_Y2.6231.00
208_W239_I2.6081.00
439_E466_K2.5921.00
495_D498_K2.5631.00
30_A72_S2.5471.00
241_S244_E2.5391.00
451_P509_I2.5351.00
107_C170_A2.5131.00
18_L73_L2.4641.00
100_D176_A2.4591.00
214_Y233_D2.4441.00
60_A190_Q2.4391.00
424_R522_E2.3861.00
63_L190_Q2.3721.00
220_F233_D2.3071.00
209_S216_S2.2641.00
217_D221_E2.2081.00
188_V268_A2.1961.00
375_S410_E2.1771.00
359_V362_L2.1541.00
179_R195_L2.1351.00
269_N274_V2.1131.00
7_V66_L2.0991.00
13_S31_V2.0661.00
17_V475_A2.0581.00
101_S178_D2.0411.00
335_H415_L2.0301.00
370_Q410_E2.0211.00
514_N517_N2.0211.00
60_A104_Q2.0031.00
226_S234_K1.9691.00
35_R61_D1.9461.00
145_A148_Q1.9421.00
295_T332_V1.9421.00
72_S76_Q1.9271.00
379_A399_L1.9231.00
378_L527_E1.9071.00
250_T253_M1.8951.00
431_K436_P1.8831.00
4_T483_A1.8821.00
251_E261_P1.8591.00
525_Y529_K1.8161.00
442_A454_M1.8111.00
9_F14_G1.7951.00
407_K410_E1.7911.00
149_R218_D1.7891.00
5_I70_I1.7831.00
45_K54_W1.7701.00
3_Y27_L1.7671.00
466_K510_T1.7661.00
192_C265_V1.7661.00
164_M168_E1.7621.00
5_I16_A1.7491.00
459_D514_N1.7471.00
266_A485_A1.7161.00
145_A149_R1.7011.00
103_G189_Y1.6961.00
98_P166_I1.6931.00
145_A218_D1.6751.00
133_D137_Q1.6551.00
421_Y524_L1.6401.00
100_D104_Q1.6331.00
459_D517_N1.6301.00
464_D510_T1.6231.00
97_L183_A1.6201.00
396_T403_T1.6081.00
339_F415_L1.5971.00
245_K266_A1.5891.00
240_H244_E1.5811.00
130_K134_R1.5781.00
3_Y18_L1.5701.00
196_K240_H1.5671.00
365_E369_H1.5621.00
337_D341_K1.5601.00
98_P235_L1.5561.00
358_G362_L1.5511.00
136_N143_G1.5471.00
428_E529_K1.5281.00
283_E501_A1.5251.00
286_K439_E1.5231.00
245_K248_S1.5031.00
530_E534_Y1.4981.00
428_E431_K1.4641.00
172_H175_E1.4511.00
192_C247_G1.4491.00
30_A73_L1.4481.00
30_A69_T1.4471.00
284_P302_E1.4451.00
469_G505_K1.4341.00
86_G482_G1.4301.00
452_F456_I1.4281.00
58_H61_D1.4211.00
260_L263_T1.4211.00
144_E148_Q1.4081.00
73_L77_T1.4071.00
60_A64_E1.3851.00
451_P511_Y1.3831.00
4_T492_G1.3821.00
188_V246_A1.3651.00
379_A383_W1.3651.00
467_I511_Y1.3531.00
370_Q409_E1.3521.00
451_P467_I1.3381.00
186_W190_Q1.3331.00
413_R417_E1.3311.00
366_K369_H1.3301.00
248_S262_G1.3291.00
93_A270_V1.3241.00
520_V524_L1.3241.00
165_Q169_E1.3231.00
363_L412_Y1.3221.00
420_A460_V1.3201.00
517_N521_Y1.3101.00
291_M457_Y1.3091.00
379_A415_L1.3061.00
28_A76_Q1.3051.00
503_M506_L1.3031.00
240_H246_A1.3031.00
28_A73_L1.3011.00
63_L67_E1.2821.00
74_L81_P1.2771.00
367_A452_F1.2721.00
516_E519_A1.2711.00
329_Q422_G1.2701.00
7_V70_I1.2681.00
462_N521_Y1.2661.00
14_G66_L1.2601.00
95_T120_V1.2601.00
287_M437_I1.2571.00
420_A456_I1.2531.00
18_L79_V1.2521.00
420_A457_Y1.2471.00
188_V196_K1.2441.00
80_D83_D1.2361.00
289_M457_Y1.2361.00
439_E464_D1.2351.00
220_F236_S1.2321.00
99_I181_I1.2321.00
14_G65_V1.2251.00
145_A222_K1.2241.00
362_L365_E1.2231.00
129_Q133_D1.2211.00
226_S235_L1.2101.00
28_A77_T1.2041.00
469_G507_K1.2021.00
42_V61_D1.2011.00
454_M511_Y1.1991.00
131_H164_M1.1911.00
362_L366_K1.1901.00
146_F154_I1.1901.00
199_N213_G1.1841.00
377_L406_T1.1821.00
7_V16_A1.1811.00
167_A174_Y1.1801.00
160_I223_L1.1781.00
456_I460_V1.1781.00
462_N522_E1.1741.00
269_N481_F1.1711.00
520_V523_K1.1671.00
400_L531_L1.1611.00
66_L187_I1.1601.00
425_M529_K1.1541.00
56_L119_Y1.1501.00
103_G195_L1.1501.00
142_E222_K1.1481.00
366_K409_E1.1471.00
424_R461_T1.1441.00
428_E525_Y1.1441.00
199_N239_I1.1421.00
331_C335_H1.1411.00
402_M406_T1.1401.00
194_S240_H1.1361.00
98_P177_A1.1341.00
218_D221_E1.1331.00
19_V26_E1.1301.00
132_A154_I1.1301.00
331_C334_D1.1251.00
516_E520_V1.1211.00
35_R42_V1.1141.00
398_M535_F1.1131.00
68_T72_S1.1121.00
283_E286_K1.1111.00
286_K441_F1.1081.00
245_K485_A1.1081.00
170_A173_I1.1061.00
62_Y183_A1.1041.00
181_I195_L1.1021.00
343_C411_I1.1001.00
449_K471_P1.0991.00
64_E68_T1.0961.00
172_H176_A1.0951.00
283_E497_K1.0891.00
130_K133_D1.0861.00
427_I461_T1.0801.00
493_Y499_A1.0791.00
3_Y83_D1.0761.00
522_E526_A1.0761.00
22_Q492_G1.0731.00
4_T486_A1.0701.00
366_K408_P1.0691.00
30_A76_Q1.0641.00
365_E368_N1.0641.00
177_A235_L1.0591.00
34_Y65_V1.0551.00
335_H379_A1.0541.00
41_T57_Q1.0531.00
142_E145_A1.0531.00
367_A370_Q1.0511.00
86_G486_A1.0501.00
3_Y79_V1.0491.00
55_A124_K1.0471.00
98_P163_V1.0461.00
59_P97_L1.0451.00
397_G402_M1.0451.00
58_H119_Y1.0441.00
361_E364_S1.0381.00
441_F466_K1.0361.00
196_K246_A1.0351.00
419_T446_I1.0351.00
245_K264_A1.0331.00
19_V479_A1.0321.00
208_W212_A1.0291.00
107_C173_I1.0251.00
131_H169_E1.0251.00
79_V83_D1.0241.00
303_E321_G1.0241.00
504_G507_K1.0181.00
86_G266_A1.0041.00
500_A503_M1.0031.00
89_I188_V1.0011.00
72_S75_E0.9981.00
199_N208_W0.9981.00
66_L70_I0.9971.00
406_T410_E0.9931.00
74_L84_I0.9911.00
287_M299_L0.9851.00
174_Y177_A0.9851.00
146_F206_A0.9811.00
515_A521_Y0.9781.00
131_H134_R0.9781.00
226_S233_D0.9771.00
133_D136_N0.9711.00
446_I453_V0.9691.00
483_A493_Y0.9611.00
160_I206_A0.9601.00
480_I503_M0.9601.00
364_S450_N0.9581.00
372_P520_V0.9571.00
16_A73_L0.9571.00
527_E530_E0.9561.00
248_S264_A0.9561.00
367_A412_Y0.9531.00
421_Y460_V0.9501.00
61_D64_E0.9501.00
484_L499_A0.9471.00
439_E510_T0.9411.00
413_R452_F0.9331.00
379_A414_A0.9311.00
107_C166_I0.9311.00
199_N317_G0.9301.00
487_G493_Y0.9271.00
266_A486_A0.9261.00
173_I176_A0.9261.00
67_E71_P0.9231.00
85_I486_A0.9231.00
32_K69_T0.9161.00
171_P175_E0.9161.00
421_Y525_Y0.9141.00
87_I263_T0.9141.00
104_Q190_Q0.9141.00
392_D395_L0.9131.00
480_I499_A0.9121.00
98_P180_I0.9091.00
399_L415_L0.9091.00
424_R460_V0.9061.00
386_N389_T0.9051.00
96_I180_I0.9041.00
288_L443_A0.8991.00
90_D474_P0.8901.00
214_Y238_S0.8901.00
94_C204_Y0.8891.00
297_H427_I0.8891.00
519_A522_E0.8891.00
200_C316_N0.8861.00
166_I173_I0.8831.00
148_Q211_K0.8811.00
285_G438_E0.8811.00
18_L84_I0.8801.00
283_E438_E0.8791.00
107_C119_Y0.8791.00
213_G241_S0.8791.00
18_L77_T0.8791.00
461_T464_D0.8761.00
189_Y195_L0.8751.00
367_A371_A0.8711.00
88_G266_A0.8701.00
400_L535_F0.8661.00
220_F225_P0.8651.00
160_I207_M0.8651.00
74_L77_T0.8641.00
163_V180_I0.8621.00
23_T502_N0.8611.00
71_P75_E0.8591.00
402_M411_I0.8581.00
185_D197_R0.8571.00
519_A523_K0.8561.00
5_I84_I0.8541.00
253_M257_T0.8531.00
5_I18_L0.8511.00
178_D234_K0.8501.00
295_T423_T0.8491.00
177_A180_I0.8481.00
455_Q514_N0.8441.00
428_E432_E0.8441.00
447_A471_P0.8431.00
371_A374_E0.8421.00
369_H409_E0.8411.00
164_M167_A0.8391.00
197_R202_A0.8381.00
373_G376_G0.8351.00
275_S443_A0.8311.00
127_A165_Q0.8281.00
82_K260_L0.8281.00
287_M440_L0.8271.00
126_H155_S0.8261.00
300_L322_Y0.8241.00
486_A492_G0.8241.00
132_A156_S0.8221.00
20_H27_L0.8211.00
134_R137_Q0.8211.00
136_N154_I0.8191.00
182_E205_K0.8191.00
307_V311_C0.8181.00
296_C328_G0.8181.00
202_A215_P0.8171.00
132_A161_P0.8151.00
19_V476_L0.8141.00
9_F187_I0.8131.00
193_G250_T0.8121.00
134_R164_M0.8111.00
427_I431_K0.8101.00
249_L257_T0.8101.00
484_L496_I0.8091.00
248_S261_P0.8081.00
442_A467_I0.8081.00
100_D106_L0.8071.00
4_T86_G0.8071.00
440_L461_T0.8061.00
19_V470_S0.8061.00
450_N453_V0.8051.00
378_L400_L0.8001.00
251_E262_G0.7991.00
196_K238_S0.7971.00
416_V456_I0.7971.00
376_G524_L0.7931.00
101_S176_A0.7911.00
460_V521_Y0.7901.00
199_N241_S0.7901.00
208_W213_G0.7891.00
89_I187_I0.7881.00
93_A201_T0.7831.00
497_K501_A0.7821.00
240_H267_V0.7811.00
163_V207_M0.7811.00
197_R237_G0.7811.00
272_A296_C0.7791.00
483_A492_G0.7751.00
344_V408_P0.7741.00
59_P119_Y0.7731.00
89_I191_L0.7731.00
106_L176_A0.7701.00
164_M224_N0.7701.00
9_F66_L0.7691.00
70_I74_L0.7691.00
84_I263_T0.7681.00
299_L430_F0.7671.00
99_I195_L0.7671.00
184_A268_A0.7671.00
395_L398_M0.7671.00
218_D222_K0.7671.00
149_R209_S0.7651.00
420_A453_V0.7651.00
498_K502_N0.7651.00
99_I103_G0.7651.00
93_A326_E0.7641.00
33_E340_V0.7621.00
279_V443_A0.7601.00
360_H363_L0.7571.00
361_E365_E0.7551.00
249_L259_L0.7551.00
455_Q511_Y0.7521.00
375_S406_T0.7501.00
123_W294_S0.7501.00
327_A426_I0.7501.00
530_E533_H0.7501.00
523_K527_E0.7491.00
98_P106_L0.7481.00
424_R529_K0.7471.00
493_Y502_N0.7461.00
33_E337_D0.7461.00
197_R239_I0.7451.00
442_A457_Y0.7431.00
367_A409_E0.7431.00
60_A186_W0.7431.00
385_G389_T0.7421.00
306_I310_M0.7411.00
6_G88_G0.7411.00
500_A504_G0.7411.00
130_K168_E0.7391.00
214_Y217_D0.7391.00
447_A454_M0.7371.00
241_S320_P0.7351.00
61_D65_V0.7321.00
366_K370_Q0.7281.00
442_A465_I0.7251.00
259_L262_G0.7241.00
289_M423_T0.7231.00
34_Y57_Q0.7221.00
425_M525_Y0.7171.00
130_K169_E0.7161.00
179_R235_L0.7161.00
148_Q305_H0.7161.00
438_E463_M0.7161.00
67_E253_M0.7151.00
364_S368_N0.7131.00
524_L527_E0.7131.00
371_A375_S0.7110.99
164_M174_Y0.7090.99
29_A472_Q0.7090.99
32_K65_V0.7090.99
289_M295_T0.7080.99
64_E67_E0.7070.99
421_Y521_Y0.7050.99
451_P455_Q0.7050.99
279_V288_L0.7050.99
302_E322_Y0.7040.99
275_S474_P0.7030.99
4_T85_I0.7030.99
146_F219_F0.6990.99
416_V450_N0.6960.99
103_G178_D0.6960.99
179_R189_Y0.6960.99
87_I249_L0.6950.99
11_T122_L0.6940.99
340_V360_H0.6940.99
512_T515_A0.6930.99
215_P236_S0.6930.99
462_N515_A0.6920.99
483_A487_G0.6910.99
368_N452_F0.6900.99
249_L263_T0.6860.99
376_G410_E0.6850.99
99_I186_W0.6840.99
493_Y496_I0.6840.99
97_L120_V0.6820.99
85_I492_G0.6820.99
429_T432_E0.6800.99
209_S214_Y0.6790.99
246_A267_V0.6790.99
133_D394_D0.6780.99
66_L69_T0.6780.99
9_F65_V0.6780.99
99_I179_R0.6780.99
100_D178_D0.6760.99
337_D360_H0.6720.99
371_A410_E0.6720.99
74_L79_V0.6720.99
150_Y219_F0.6710.99
529_K533_H0.6700.99
216_S219_F0.6680.99
339_F412_Y0.6670.99
70_I73_L0.6660.99
26_E29_A0.6660.99
253_M262_G0.6650.99
242_V268_A0.6650.99
517_N522_E0.6630.99
14_G34_Y0.6630.99
213_G317_G0.6610.99
515_A519_A0.6610.99
376_G413_R0.6610.99
395_L399_L0.6590.99
60_A105_P0.6580.99
370_Q375_S0.6540.99
363_L367_A0.6530.99
440_L465_I0.6520.99
523_K526_A0.6510.99
345_P357_I0.6510.99
281_I286_K0.6500.99
63_L253_M0.6490.99
332_V419_T0.6480.99
497_K500_A0.6460.99
200_C269_N0.6460.99
249_L260_L0.6440.99
382_W386_N0.6400.99
238_S244_E0.6390.99
357_I363_L0.6390.99
289_M440_L0.6390.99
29_A76_Q0.6390.99
135_L223_L0.6380.99
174_Y224_N0.6380.99
309_G432_E0.6370.99
370_Q374_E0.6360.99
92_T123_W0.6360.99
259_L263_T0.6360.99
70_I257_T0.6350.99
339_F343_C0.6320.99
188_V192_C0.6320.99
67_E190_Q0.6300.99
502_N506_L0.6290.99
121_K127_A0.6280.99
99_I189_Y0.6270.99
484_L487_G0.6260.99
364_S367_A0.6250.99
372_P413_R0.6250.99
91_F201_T0.6230.99
380_L386_N0.6220.99
186_W189_Y0.6210.99
281_I288_L0.6200.99
522_E525_Y0.6200.99
364_S451_P0.6200.99
86_G264_A0.6200.99
184_A201_T0.6200.99
456_I521_Y0.6190.99
105_P119_Y0.6180.99
56_L127_A0.6170.99
221_E233_D0.6170.99
78_G81_P0.6160.99
245_K486_A0.6160.99
91_F183_A0.6160.99
317_G320_P0.6160.99
135_L161_P0.6140.99
241_S317_G0.6130.99
200_C242_V0.6130.99
185_D195_L0.6130.99
278_A473_A0.6120.98
432_E529_K0.6110.98
163_V235_L0.6110.98
67_E257_T0.6100.98
270_V273_H0.6100.98
225_P236_S0.6090.98
469_G506_L0.6090.98
261_P264_A0.6080.98
493_Y497_K0.6080.98
464_D513_P0.6030.98
146_F223_L0.6030.98
374_E378_L0.6010.98
207_M236_S0.6010.98
374_E413_R0.6000.98
417_E456_I0.6000.98
19_V475_A0.5990.98
295_T457_Y0.5980.98
248_S251_E0.5970.98
103_G179_R0.5970.98
104_Q176_A0.5960.98
96_I159_M0.5950.98
498_K501_A0.5940.98
44_P54_W0.5940.98
379_A418_A0.5930.98
60_A119_Y0.5930.98
526_A529_K0.5910.98
164_M223_L0.5910.98
298_V324_G0.5870.98
68_T71_P0.5840.98
81_P84_I0.5840.98
271_D293_T0.5820.98
480_I484_L0.5820.98
521_Y524_L0.5810.98
264_A486_A0.5800.98
390_L425_M0.5790.98
413_R456_I0.5780.98
144_E147_L0.5770.98
329_Q426_I0.5770.98
384_N404_L0.5760.98
257_T263_T0.5760.98
152_G158_W0.5750.98
375_S405_L0.5750.98
376_G527_E0.5750.98
389_T392_D0.5750.98
54_W127_A0.5750.98
440_L463_M0.5740.98
154_I206_A0.5730.98
396_T399_L0.5730.98
419_T453_V0.5720.98
243_G485_A0.5700.98
386_N392_D0.5670.98
378_L421_Y0.5660.98
484_L495_D0.5660.98
221_E226_S0.5660.98
503_M507_K0.5650.97
272_A290_I0.5640.97
158_W204_Y0.5640.97
291_M442_A0.5620.97
383_W386_N0.5620.97
336_F364_S0.5620.97
380_L531_L0.5610.97
128_A161_P0.5600.97
363_L452_F0.5600.97
249_L258_G0.5590.97
385_G388_S0.5570.97
17_V26_E0.5560.97
249_L253_M0.5560.97
496_I500_A0.5560.97
276_V298_V0.5550.97
499_A503_M0.5540.97
475_A478_S0.5540.97
454_M467_I0.5510.97
439_E463_M0.5500.97
67_E70_I0.5490.97
377_L411_I0.5490.97
390_L395_L0.5490.97
390_L529_K0.5490.97
253_M258_G0.5490.97
492_G495_D0.5480.97
380_L398_M0.5480.97
97_L105_P0.5480.97
94_C123_W0.5470.97
339_F411_I0.5450.97
93_A204_Y0.5440.97
55_A122_L0.5440.97
219_F223_L0.5430.97
150_Y206_A0.5430.97
364_S452_F0.5430.97
87_I265_V0.5430.97
380_L532_V0.5430.97
253_M259_L0.5430.97
470_S476_L0.5420.97
11_T123_W0.5410.97
484_L493_Y0.5410.97
127_A169_E0.5400.97
59_P120_V0.5400.97
60_A63_L0.5400.97
377_L414_A0.5400.97
421_Y527_E0.5400.97
365_E451_P0.5380.97
188_V265_V0.5380.97
242_V269_N0.5370.97
437_I463_M0.5350.97
522_E529_K0.5320.96
12_L15_R0.5320.96
390_L532_V0.5320.96
342_T407_K0.5310.96
221_E224_N0.5310.96
381_D418_A0.5300.96
299_L437_I0.5300.96
495_D499_A0.5300.96
57_Q122_L0.5280.96
95_T122_L0.5280.96
277_P480_I0.5270.96
462_N517_N0.5260.96
54_W121_K0.5260.96
421_Y456_I0.5240.96
243_G484_L0.5240.96
193_G252_K0.5240.96
174_Y226_S0.5240.96
167_A224_N0.5230.96
71_P74_L0.5220.96
297_H426_I0.5220.96
65_V68_T0.5210.96
92_T120_V0.5210.96
357_I365_E0.5210.96
458_A465_I0.5200.96
447_A467_I0.5190.96
57_Q92_T0.5190.96
94_C294_S0.5190.96
211_K214_Y0.5190.96
364_S416_V0.5160.96
174_Y178_D0.5160.96
307_V310_M0.5160.96
121_K166_I0.5150.96
457_Y461_T0.5150.96
84_I259_L0.5150.96
13_S293_T0.5140.96
200_C273_H0.5130.96
287_M427_I0.5130.96
290_I296_C0.5130.96
328_G387_R0.5110.95
289_M297_H0.5110.95
56_L121_K0.5110.95
26_E470_S0.5110.95
25_E469_G0.5100.95
290_I443_A0.5100.95
90_D478_S0.5090.95
211_K304_V0.5090.95
156_S393_A0.5070.95
456_I524_L0.5070.95
336_F363_L0.5060.95
219_F222_K0.5060.95
423_T457_Y0.5060.95
431_K437_I0.5050.95
277_P318_I0.5040.95
293_T445_G0.5030.95
129_Q156_S0.5030.95
417_E421_Y0.5020.95
493_Y503_M0.5020.95
377_L402_M0.5010.95
74_L80_D0.5010.95
6_G475_A0.5010.95
161_P206_A0.5000.95
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3ll3A 2 0.8768 100 0.161 Contact Map
3qdkA 2 0.9768 100 0.168 Contact Map
3hz6A 1 0.8625 100 0.19 Contact Map
3ifrA 2 0.8714 100 0.19 Contact Map
2itmA 2 0.8482 100 0.191 Contact Map
3l0qA 2 0.9107 100 0.198 Contact Map
3wxlA 2 0.8768 100 0.205 Contact Map
3ezwA 3 0.8696 100 0.213 Contact Map
2d4wA 2 0.8714 100 0.214 Contact Map
3h3nX 3 0.8696 100 0.214 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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