EABN1 - BACSU - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

EABN1 - Extracellular endo-alpha-(1->5)-L-arabinanase 1

UniProt:	P94522	Sequences: MKKKKTWKRFLHFSSAALAAGLIFTSAAPAEAAFWGASNELLHDPTMIKEGSSWYALGTGLTEERGLRVLKSSDAKNWTVQKSIFTTPLSWWSNYVPNYGQNQWAPDIQYYNGKYWLYYSVSSFGSNTSAIGLASSTSISSGGWKDEGLVIRSTSSNNYNAIDPELTFDKDGNPWLAFGSFWSGIKLTKLDKSTMKPTGSLYSIAARPNNGGALEAPTLTYQNGYYYLMVSFDKCCDGVNSTYKIAYGRSKSITGPYLDKSGKSMLEGGGTILDSGNDQWKGPGGQDIVNGNILVRHAYDANDNGIPKLLINDLNWSSGWPSY	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	323 (265)
Sequences:	7367 (4707)
Seq/√Len:	289.1

ECOLI - YAGH
BACSU - EABN1 XYND EABN2 XYNB

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
173_N	189_K	6.307	1.00
53_S	71_K	4.833	1.00
74_D	77_N	4.828	1.00
225_Y	251_K	4.803	1.00
170_K	221_Y	4.376	1.00
114_K	137_T	4.291	1.00
53_S	73_S	3.986	1.00
138_S	141_S	3.766	1.00
114_K	135_S	3.662	1.00
225_Y	249_R	3.334	1.00
189_K	198_T	3.305	1.00
57_L	144_W	3.198	1.00
191_D	196_K	2.949	1.00
292_N	313_D	2.779	1.00
136_S	143_G	2.733	1.00
168_F	174_P	2.649	1.00
50_E	115_Y	2.585	1.00
71_K	81_Q	2.571	1.00
177_A	187_L	2.545	1.00
187_L	254_T	2.495	1.00
317_S	320_W	2.424	1.00
50_E	110_Y	2.146	1.00
57_L	108_I	2.138	1.00
110_Y	113_G	2.131	1.00
188_T	197_P	2.110	1.00
253_I	257_Y	2.019	1.00
191_D	195_M	1.921	1.00
193_S	196_K	1.905	1.00
49_K	52_S	1.883	1.00
108_I	117_L	1.875	1.00
202_Y	254_T	1.814	1.00
191_D	198_T	1.766	1.00
288_I	314_L	1.765	1.00
135_S	147_E	1.752	1.00
71_K	79_T	1.713	1.00
186_K	203_S	1.656	1.00
203_S	206_A	1.641	1.00
178_F	188_T	1.639	1.00
222_Q	316_W	1.632	1.00
249_R	320_W	1.630	1.00
84_I	117_L	1.624	1.00
54_W	72_S	1.533	1.00
177_A	219_L	1.507	1.00
229_M	247_Y	1.504	1.00
177_A	253_I	1.495	1.00
296_R	312_N	1.483	1.00
177_A	257_Y	1.446	1.00
249_R	258_L	1.441	1.00
295_V	311_I	1.432	1.00
52_S	73_S	1.408	1.00
250_S	257_Y	1.394	1.00
68_R	80_V	1.379	1.00
221_Y	226_Y	1.373	1.00
220_T	288_I	1.370	1.00
220_T	316_W	1.366	1.00
220_T	229_M	1.360	1.00
42_L	70_L	1.357	1.00
249_R	261_S	1.347	1.00
250_S	256_P	1.345	1.00
167_T	226_Y	1.345	1.00
116_W	133_L	1.340	1.00
167_T	219_L	1.340	1.00
67_L	117_L	1.327	1.00
251_K	258_L	1.323	1.00
224_G	251_K	1.321	1.00
219_L	257_Y	1.321	1.00
48_I	115_Y	1.285	1.00
87_T	90_S	1.283	1.00
133_L	195_M	1.262	1.00
191_D	194_T	1.259	1.00
223_N	319_G	1.253	1.00
33_A	36_G	1.251	1.00
164_P	176_L	1.245	1.00
42_L	58_G	1.242	1.00
72_S	75_A	1.232	1.00
171_D	221_Y	1.223	1.00
298_A	310_L	1.206	1.00
135_S	145_K	1.185	1.00
136_S	142_G	1.184	1.00
136_S	141_S	1.184	1.00
221_Y	224_G	1.168	1.00
214_L	230_V	1.162	1.00
286_Q	294_L	1.158	1.00
57_L	140_S	1.157	1.00
131_I	176_L	1.150	1.00
68_R	83_S	1.147	1.00
175_W	254_T	1.135	1.00
119_Y	146_D	1.126	1.00
205_A	248_G	1.120	1.00
187_L	253_I	1.120	1.00
47_M	295_V	1.118	1.00
118_Y	194_T	1.116	1.00
85_F	134_A	1.115	1.00
118_Y	176_L	1.106	1.00
72_S	77_N	1.106	1.00
192_K	196_K	1.104	1.00
107_D	165_E	1.097	1.00
137_T	145_K	1.086	1.00
56_A	309_L	1.084	1.00
58_G	70_L	1.081	1.00
187_L	204_I	1.080	1.00
67_L	103_Q	1.079	1.00
110_Y	115_Y	1.077	1.00
187_L	257_Y	1.068	1.00
245_I	294_L	1.063	1.00
167_T	253_I	1.050	1.00
89_L	92_W	1.048	1.00
169_D	221_Y	1.046	1.00
232_F	246_A	1.042	1.00
72_S	78_W	1.032	1.00
293_I	313_D	1.020	1.00
75_A	311_I	1.017	1.00
111_Y	174_P	1.006	1.00
199_G	202_Y	1.003	1.00
184_G	203_S	1.003	1.00
218_T	287_D	0.999	1.00
86_T	89_L	0.993	1.00
176_L	188_T	0.988	1.00
89_L	146_D	0.974	1.00
201_L	204_I	0.970	1.00
280_W	310_L	0.967	1.00
189_K	199_G	0.967	1.00
227_Y	247_Y	0.963	1.00
117_L	134_A	0.961	1.00
50_E	53_S	0.957	1.00
69_V	108_I	0.953	1.00
118_Y	166_L	0.953	1.00
284_G	288_I	0.952	1.00
132_G	146_D	0.952	1.00
185_I	230_V	0.951	1.00
180_S	186_K	0.951	1.00
177_A	228_L	0.951	1.00
70_L	80_V	0.949	1.00
71_K	141_S	0.948	1.00
178_F	201_L	0.947	1.00
205_A	259_D	0.946	1.00
81_Q	141_S	0.941	1.00
109_Q	168_F	0.941	1.00
166_L	174_P	0.939	1.00
88_P	91_W	0.938	1.00
185_I	217_P	0.934	1.00
192_K	195_M	0.929	1.00
229_M	245_I	0.926	1.00
287_D	295_V	0.925	1.00
213_A	217_P	0.922	1.00
138_S	142_G	0.916	1.00
219_L	253_I	0.915	1.00
87_T	93_S	0.913	1.00
80_V	83_S	0.909	1.00
252_S	256_P	0.907	1.00
282_G	299_Y	0.906	1.00
138_S	143_G	0.904	1.00
67_L	119_Y	0.903	1.00
106_P	117_L	0.901	1.00
229_M	288_I	0.901	1.00
190_L	195_M	0.890	1.00
222_Q	225_Y	0.888	1.00
252_S	257_Y	0.887	1.00
62_T	66_G	0.886	1.00
175_W	189_K	0.877	1.00
54_W	289_V	0.874	1.00
264_S	267_E	0.869	1.00
123_S	126_S	0.866	1.00
89_L	93_S	0.862	1.00
73_S	79_T	0.861	1.00
293_I	311_I	0.861	1.00
48_I	108_I	0.855	1.00
118_Y	133_L	0.854	1.00
284_G	287_D	0.852	1.00
138_S	144_W	0.851	1.00
166_L	176_L	0.850	1.00
32_A	35_W	0.850	1.00
109_Q	166_L	0.847	1.00
188_T	199_G	0.843	1.00
112_N	174_P	0.840	1.00
222_Q	319_G	0.838	1.00
131_I	164_P	0.838	1.00
201_L	205_A	0.834	1.00
57_L	69_V	0.832	1.00
85_F	88_P	0.832	1.00
35_W	38_S	0.830	1.00
285_G	288_I	0.828	1.00
185_I	228_L	0.826	1.00
169_D	172_G	0.824	1.00
177_A	217_P	0.823	1.00
283_P	298_A	0.820	1.00
285_G	289_V	0.820	1.00
75_A	78_W	0.818	1.00
103_Q	119_Y	0.816	1.00
55_Y	69_V	0.808	1.00
47_M	287_D	0.800	0.99
187_L	219_L	0.798	0.99
289_V	295_V	0.798	0.99
188_T	201_L	0.796	0.99
122_S	129_S	0.796	0.99
258_L	261_S	0.794	0.99
269_G	278_D	0.788	0.99
169_D	226_Y	0.786	0.99
280_W	284_G	0.782	0.99
60_G	68_R	0.782	0.99
300_D	308_K	0.782	0.99
43_H	307_P	0.770	0.99
53_S	81_Q	0.769	0.99
57_L	106_P	0.759	0.99
119_Y	132_G	0.757	0.99
90_S	93_S	0.756	0.99
87_T	91_W	0.750	0.99
140_S	143_G	0.749	0.99
229_M	286_Q	0.749	0.99
190_L	194_T	0.745	0.99
159_Y	197_P	0.744	0.99
200_S	203_S	0.743	0.99
233_D	244_K	0.741	0.99
55_Y	71_K	0.740	0.99
98_N	101_Q	0.740	0.99
54_W	75_A	0.736	0.99
88_P	93_S	0.735	0.99
280_W	298_A	0.733	0.99
296_R	310_L	0.729	0.99
33_A	76_K	0.725	0.99
119_Y	134_A	0.725	0.99
42_L	56_A	0.722	0.99
233_D	242_T	0.721	0.99
186_K	201_L	0.719	0.99
229_M	314_L	0.719	0.99
250_S	255_G	0.717	0.99
123_S	130_A	0.715	0.99
167_T	170_K	0.714	0.99
165_E	177_A	0.712	0.99
82_K	143_G	0.708	0.99
111_Y	168_F	0.708	0.99
246_A	259_D	0.698	0.99
120_S	164_P	0.698	0.99
297_H	300_D	0.698	0.99
250_S	253_I	0.697	0.99
111_Y	116_W	0.689	0.98
34_F	37_A	0.688	0.98
230_V	246_A	0.687	0.98
44_D	105_A	0.687	0.98
227_Y	249_R	0.685	0.98
185_I	214_L	0.684	0.98
190_L	193_S	0.682	0.98
176_L	190_L	0.681	0.98
245_I	286_Q	0.680	0.98
170_K	224_G	0.680	0.98
229_M	316_W	0.679	0.98
58_G	216_A	0.677	0.98
59_T	106_P	0.674	0.98
46_T	218_T	0.674	0.98
69_V	144_W	0.673	0.98
249_R	316_W	0.673	0.98
32_A	36_G	0.668	0.98
101_Q	122_S	0.668	0.98
248_G	257_Y	0.666	0.98
147_E	195_M	0.665	0.98
111_Y	166_L	0.665	0.98
181_F	184_G	0.663	0.98
234_K	239_V	0.662	0.98
165_E	218_T	0.661	0.98
44_D	59_T	0.661	0.98
85_F	91_W	0.661	0.98
247_Y	265_M	0.660	0.98
162_I	217_P	0.658	0.98
258_L	264_S	0.657	0.98
49_K	289_V	0.654	0.98
173_N	198_T	0.653	0.98
67_L	106_P	0.653	0.98
232_F	244_K	0.650	0.98
286_Q	295_V	0.650	0.98
243_Y	284_G	0.649	0.98
69_V	84_I	0.649	0.98
105_A	285_G	0.648	0.98
294_L	314_L	0.642	0.97
46_T	287_D	0.639	0.97
105_A	163_D	0.637	0.97
295_V	309_L	0.635	0.97
280_W	283_P	0.634	0.97
200_S	204_I	0.633	0.97
202_Y	206_A	0.631	0.97
49_K	54_W	0.631	0.97
118_Y	190_L	0.630	0.97
46_T	107_D	0.630	0.97
281_K	284_G	0.628	0.97
116_W	135_S	0.626	0.97
47_M	54_W	0.625	0.97
199_G	206_A	0.624	0.97
263_K	267_E	0.624	0.97
225_Y	250_S	0.623	0.97
44_D	285_G	0.619	0.97
136_S	144_W	0.618	0.97
131_I	150_V	0.617	0.97
118_Y	164_P	0.615	0.97
231_S	286_Q	0.615	0.97
98_N	123_S	0.613	0.97
74_D	78_W	0.612	0.97
217_P	228_L	0.609	0.97
218_T	286_Q	0.609	0.97
244_K	263_K	0.608	0.97
170_K	226_Y	0.607	0.96
55_Y	115_Y	0.607	0.96
47_M	75_A	0.606	0.96
230_V	248_G	0.606	0.96
101_Q	123_S	0.604	0.96
67_L	134_A	0.603	0.96
178_F	186_K	0.599	0.96
187_L	202_Y	0.598	0.96
243_Y	282_G	0.597	0.96
248_G	265_M	0.596	0.96
118_Y	131_I	0.596	0.96
47_M	289_V	0.594	0.96
112_N	172_G	0.591	0.96
181_F	213_A	0.588	0.96
199_G	204_I	0.587	0.96
293_I	298_A	0.586	0.96
228_L	257_Y	0.584	0.96
253_I	256_P	0.583	0.96
195_M	198_T	0.579	0.95
104_W	122_S	0.578	0.95
33_A	293_I	0.577	0.95
121_V	129_S	0.575	0.95
219_L	226_Y	0.575	0.95
180_S	184_G	0.573	0.95
303_D	308_K	0.572	0.95
88_P	92_W	0.571	0.95
57_L	117_L	0.571	0.95
294_L	312_N	0.569	0.95
109_Q	174_P	0.568	0.95
129_S	180_S	0.566	0.95
112_N	116_W	0.565	0.95
111_Y	194_T	0.564	0.95
241_S	302_N	0.563	0.95
252_S	255_G	0.561	0.95
295_V	298_A	0.561	0.95
245_I	296_R	0.557	0.94
219_L	228_L	0.557	0.94
233_D	246_A	0.555	0.94
294_L	298_A	0.554	0.94
169_D	253_I	0.554	0.94
198_T	201_L	0.552	0.94
63_E	66_G	0.551	0.94
37_A	309_L	0.551	0.94
49_K	53_S	0.549	0.94
57_L	67_L	0.548	0.94
43_H	61_L	0.547	0.94
201_L	206_A	0.547	0.94
86_T	90_S	0.547	0.94
31_E	34_F	0.547	0.94
167_T	171_D	0.545	0.94
118_Y	195_M	0.544	0.94
90_S	103_Q	0.543	0.94
72_S	76_K	0.543	0.94
231_S	243_Y	0.542	0.94
171_D	175_W	0.541	0.93
137_T	143_G	0.541	0.93
150_V	176_L	0.540	0.93
208_P	211_G	0.537	0.93
65_R	306_I	0.535	0.93
200_S	205_A	0.535	0.93
283_P	286_Q	0.534	0.93
263_K	266_L	0.534	0.93
192_K	198_T	0.532	0.93
167_T	173_N	0.530	0.93
141_S	144_W	0.529	0.93
59_T	243_Y	0.528	0.93
315_N	318_S	0.528	0.93
99_Y	119_Y	0.528	0.93
41_L	306_I	0.526	0.93
86_T	91_W	0.526	0.93
59_T	104_W	0.525	0.92
83_S	86_T	0.525	0.92
174_P	190_L	0.524	0.92
205_A	214_L	0.523	0.92
134_A	144_W	0.522	0.92
163_D	285_G	0.522	0.92
120_S	162_I	0.522	0.92
44_D	104_W	0.521	0.92
166_L	190_L	0.519	0.92
134_A	147_E	0.518	0.92
292_N	315_N	0.518	0.92
268_G	277_N	0.518	0.92
151_I	196_K	0.518	0.92
230_V	265_M	0.514	0.92
57_L	84_I	0.514	0.92
40_E	70_L	0.514	0.92
226_Y	250_S	0.513	0.92
250_S	258_L	0.511	0.91
67_L	84_I	0.509	0.91
123_S	128_T	0.509	0.91
45_P	56_A	0.508	0.91
146_D	149_L	0.508	0.91
216_A	286_Q	0.507	0.91
160_N	180_S	0.506	0.91
283_P	297_H	0.506	0.91
85_F	90_S	0.505	0.91
160_N	184_G	0.505	0.91
293_I	296_R	0.504	0.91
55_Y	81_Q	0.501	0.91
305_G	308_K	0.500	0.91

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1uv4A	1	0.8978	100	0.271	Contact Map
2x8sA	1	0.8607	100	0.276	Contact Map
3c2uA	3	0.8514	100	0.298	Contact Map
1yifA	3	0.8483	100	0.299	Contact Map
3cu9A	2	0.9288	100	0.301	Contact Map
2exhA	3	0.8483	100	0.303	Contact Map
1gyhA	1	0.8762	100	0.306	Contact Map
4kcbA	1	0.8885	100	0.308	Contact Map
1yrzA	1	0.8483	100	0.308	Contact Map
4kc7A	1	0.8607	100	0.32	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0096 seconds.