XYNB - BACSU - GREMLIN Contacts

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XYNB - Beta-xylosidase

UniProt:	P94489	Sequences: MKITNPVLKGFNPDPSICRAGEDYYIAVSTFEWFPGVQIHHSKDLVNWHLVAHPLQRVSQLDMKGNPNSGGVWAPCLSYSDGKFWLIYTDVKVVDGAWKDCHNYLVTCETINGDWSEPIKLNSSGFDASLFHDTDGKKYLLNMLWDHRIDRHSFGGIVIQEYSDKEQKLIGKPKVIFEGTDRKLTEAPHLYHIGNYYYLLTAEGGTRYEHAATIARSANIEGPYEVHPDNPILTSWHDPGNPLQKCGHASIVQTHTDEWYLAHLTGRPIHPDDDSIFQQRGYCPLGRETAIQKLYWKDEWPYVVGGKEGSLEVDAPSIPETIFEATYPEVDEFEDSTLNINFQTLRIPFTNELGSLTQAPNHLRLFGHESLTSTFTQAFVARRWQSLHFEAETAVEFYPENFQQAAGLVNYYNTENWTALQVTHDEELGRILELTICDNFSFSQPLNNKIVIPREVKYVYLRVNIEKDKYYYFYSFNKEDWHKIDIALESKKLSDDYIRGGGFFTGAFVGMQCQDTSGNHIPADFRYFRYKEK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	533 (480)
Sequences:	2762 (2085)
Seq/√Len:	95.2

ECOLI - YAGH
BACSU - XYNB XYND EABN2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
23_D	41_H	7.557	1.00
137_K	161_E	6.407	1.00
83_K	109_E	5.571	1.00
196_Y	218_A	5.465	1.00
44_D	47_N	5.417	1.00
108_C	114_D	4.638	1.00
364_R	524_D	4.521	1.00
134_T	192_H	4.511	1.00
254_T	258_E	4.234	1.00
22_E	43_K	3.968	1.00
460_Y	475_S	3.326	1.00
54_P	86_L	3.235	1.00
23_D	43_K	3.189	1.00
83_K	107_T	2.900	1.00
359_A	362_H	2.857	1.00
251_I	294_L	2.817	1.00
77_L	86_L	2.785	1.00
394_A	458_Y	2.776	1.00
37_V	86_L	2.759	1.00
7_V	262_A	2.608	1.00
57_R	60_Q	2.606	1.00
159_I	221_E	2.540	1.00
200_L	214_I	2.446	1.00
220_I	224_Y	2.425	1.00
174_K	221_E	2.407	1.00
24_Y	254_T	2.354	1.00
330_V	529_R	2.278	1.00
59_S	117_E	2.273	1.00
216_R	300_W	2.269	1.00
390_E	462_R	2.259	1.00
194_G	299_E	2.247	1.00
390_E	464_N	2.232	1.00
200_L	212_A	2.213	1.00
392_E	527_Y	2.211	1.00
163_S	166_E	2.208	1.00
355_S	358_Q	2.154	1.00
406_A	523_A	2.139	1.00
364_R	522_P	2.136	1.00
258_E	293_K	2.130	1.00
261_L	303_V	2.122	1.00
473_F	483_K	2.115	1.00
72_V	88_Y	2.067	1.00
219_N	224_Y	2.061	1.00
331_D	342_F	2.056	1.00
253_Q	257_D	2.044	1.00
391_A	528_F	2.043	1.00
394_A	460_Y	2.043	1.00
163_S	168_K	2.025	1.00
196_Y	216_R	2.024	1.00
359_A	396_E	2.022	1.00
37_V	88_Y	2.020	1.00
409_V	510_G	2.013	1.00
343_Q	508_F	2.007	1.00
263_H	292_Q	2.005	1.00
161_E	170_I	1.982	1.00
163_S	167_Q	1.968	1.00
396_E	458_Y	1.968	1.00
212_A	249_A	1.958	1.00
12_N	40_H	1.940	1.00
159_I	176_I	1.930	1.00
475_S	478_K	1.906	1.00
464_N	473_F	1.887	1.00
192_H	195_N	1.856	1.00
394_A	527_Y	1.845	1.00
462_R	481_W	1.840	1.00
394_A	526_R	1.837	1.00
410_N	463_V	1.837	1.00
41_H	49_H	1.833	1.00
334_E	526_R	1.814	1.00
253_Q	259_W	1.799	1.00
355_S	359_A	1.778	1.00
332_E	529_R	1.750	1.00
185_T	201_T	1.738	1.00
177_F	226_V	1.726	1.00
469_K	487_A	1.714	1.00
108_C	112_N	1.710	1.00
141_L	159_I	1.708	1.00
27_A	77_L	1.704	1.00
260_Y	293_K	1.696	1.00
477_N	480_D	1.693	1.00
193_I	299_E	1.687	1.00
22_E	255_H	1.680	1.00
28_V	187_A	1.666	1.00
108_C	113_G	1.641	1.00
471_Y	483_K	1.641	1.00
462_R	473_F	1.634	1.00
359_A	524_D	1.625	1.00
19_R	22_E	1.620	1.00
162_Y	167_Q	1.612	1.00
159_I	220_I	1.611	1.00
160_Q	169_L	1.602	1.00
86_L	106_V	1.601	1.00
475_S	481_W	1.591	1.00
131_F	190_L	1.584	1.00
110_T	114_D	1.576	1.00
391_A	408_L	1.567	1.00
475_S	479_E	1.559	1.00
389_F	465_I	1.538	1.00
214_I	232_I	1.535	1.00
393_T	527_Y	1.521	1.00
475_S	480_D	1.503	1.00
20_A	84_F	1.499	1.00
135_D	192_H	1.491	1.00
388_H	466_E	1.490	1.00
55_L	72_V	1.482	1.00
395_V	422_V	1.481	1.00
105_L	167_Q	1.479	1.00
217_S	224_Y	1.458	1.00
362_H	524_D	1.455	1.00
408_L	463_V	1.453	1.00
87_I	140_L	1.451	1.00
139_Y	221_E	1.443	1.00
30_T	38_Q	1.431	1.00
37_V	106_V	1.428	1.00
3_I	260_Y	1.424	1.00
37_V	72_V	1.415	0.99
312_E	316_P	1.404	0.99
159_I	224_Y	1.396	0.99
511_M	525_F	1.391	0.99
249_A	261_L	1.388	0.99
81_D	136_G	1.379	0.99
405_A	512_Q	1.373	0.99
121_L	140_L	1.364	0.99
142_N	160_Q	1.364	0.99
50_L	53_H	1.360	0.99
460_Y	477_N	1.358	0.99
216_R	225_E	1.356	0.99
214_I	301_P	1.347	0.99
392_E	462_R	1.344	0.99
265_T	290_A	1.343	0.99
19_R	255_H	1.332	0.99
177_F	215_A	1.327	0.99
20_A	79_Y	1.326	0.99
393_T	525_F	1.326	0.99
38_Q	53_H	1.320	0.99
67_P	70_G	1.295	0.99
20_A	23_D	1.283	0.99
392_E	460_Y	1.283	0.99
19_R	253_Q	1.279	0.99
191_Y	200_L	1.269	0.99
246_C	265_T	1.264	0.99
318_I	321_T	1.263	0.99
397_F	404_Q	1.255	0.99
175_V	178_E	1.255	0.99
53_H	343_Q	1.253	0.99
191_Y	251_I	1.252	0.99
57_R	117_E	1.250	0.99
355_S	364_R	1.248	0.99
422_V	452_I	1.247	0.99
27_A	54_P	1.245	0.99
17_I	262_A	1.244	0.99
133_D	192_H	1.229	0.99
9_K	386_S	1.223	0.98
51_V	112_N	1.213	0.98
460_Y	481_W	1.209	0.98
60_Q	106_V	1.198	0.98
225_E	300_W	1.195	0.98
250_S	262_A	1.194	0.98
331_D	339_N	1.193	0.98
332_E	526_R	1.186	0.98
27_A	75_P	1.185	0.98
198_Y	214_I	1.184	0.98
243_L	290_A	1.178	0.98
24_Y	255_H	1.175	0.98
131_F	197_Y	1.175	0.98
292_Q	303_V	1.173	0.98
319_P	322_I	1.172	0.98
37_V	75_P	1.162	0.98
193_I	296_W	1.160	0.98
359_A	364_R	1.154	0.98
193_I	253_Q	1.154	0.98
355_S	360_P	1.153	0.98
28_V	40_H	1.152	0.98
471_Y	487_A	1.140	0.98
161_E	171_G	1.140	0.98
437_C	440_F	1.139	0.98
40_H	50_L	1.137	0.98
464_N	471_Y	1.132	0.97
356_L	359_A	1.123	0.97
89_T	128_A	1.121	0.97
133_D	136_G	1.121	0.97
218_A	225_E	1.119	0.97
381_A	508_F	1.115	0.97
131_F	135_D	1.114	0.97
27_A	86_L	1.111	0.97
132_H	138_K	1.109	0.97
52_A	114_D	1.100	0.97
54_P	106_V	1.098	0.97
192_H	197_Y	1.091	0.97
418_T	484_I	1.090	0.97
3_I	46_V	1.090	0.97
307_K	310_S	1.086	0.97
37_V	54_P	1.084	0.97
456_V	476_F	1.082	0.97
262_A	289_T	1.081	0.97
358_Q	366_F	1.070	0.96
55_L	106_V	1.067	0.96
133_D	197_Y	1.066	0.96
389_F	509_V	1.056	0.96
349_F	352_E	1.052	0.96
355_S	362_H	1.044	0.96
391_A	509_V	1.042	0.96
341_N	382_R	1.041	0.96
41_H	51_V	1.038	0.96
141_L	190_L	1.036	0.96
216_R	296_W	1.033	0.96
25_Y	112_N	1.030	0.96
406_A	525_F	1.023	0.95
358_Q	362_H	1.022	0.95
392_E	529_R	1.022	0.95
339_N	342_F	1.018	0.95
318_I	324_E	1.017	0.95
466_E	471_Y	1.015	0.95
362_H	526_R	1.015	0.95
446_L	449_K	1.015	0.95
212_A	261_L	1.011	0.95
393_T	511_M	1.008	0.95
318_I	322_I	1.008	0.95
70_G	92_K	1.006	0.95
76_C	129_S	1.004	0.95
78_S	132_H	1.004	0.95
12_N	28_V	1.002	0.95
392_E	481_W	0.996	0.95
102_H	120_K	0.996	0.95
107_T	116_S	0.996	0.95
73_W	91_V	0.990	0.94
217_S	221_E	0.989	0.94
294_L	301_P	0.987	0.94
144_L	158_V	0.980	0.94
296_W	301_P	0.980	0.94
42_S	45_L	0.978	0.94
434_L	437_C	0.978	0.94
196_Y	217_S	0.975	0.94
410_N	470_Y	0.974	0.94
13_P	31_F	0.974	0.94
320_E	324_E	0.972	0.94
262_A	291_I	0.970	0.94
18_C	84_F	0.969	0.94
157_I	201_T	0.967	0.94
254_T	260_Y	0.966	0.94
81_D	85_W	0.964	0.94
297_K	302_Y	0.962	0.94
295_Y	302_Y	0.962	0.94
138_K	164_D	0.961	0.94
211_A	236_W	0.959	0.93
245_K	283_C	0.957	0.93
191_Y	250_S	0.953	0.93
190_L	224_Y	0.951	0.93
41_H	112_N	0.948	0.93
143_M	155_G	0.944	0.93
182_R	211_A	0.939	0.93
180_T	183_K	0.938	0.93
318_I	323_F	0.931	0.92
316_P	319_P	0.929	0.92
162_Y	170_I	0.926	0.92
44_D	48_W	0.925	0.92
87_I	166_E	0.925	0.92
27_A	37_V	0.924	0.92
129_S	141_L	0.921	0.92
105_L	162_Y	0.915	0.92
17_I	252_V	0.914	0.92
313_V	316_P	0.911	0.92
140_L	187_A	0.908	0.91
357_T	360_P	0.905	0.91
162_Y	166_E	0.905	0.91
232_I	303_V	0.902	0.91
331_D	341_N	0.902	0.91
108_C	111_I	0.901	0.91
405_A	421_Q	0.901	0.91
338_L	356_L	0.901	0.91
193_I	259_W	0.890	0.91
460_Y	527_Y	0.886	0.90
366_F	522_P	0.885	0.90
356_L	361_N	0.884	0.90
25_Y	84_F	0.884	0.90
190_L	220_I	0.883	0.90
66_N	92_K	0.882	0.90
160_Q	173_P	0.879	0.90
88_Y	106_V	0.878	0.90
217_S	223_P	0.876	0.90
295_Y	304_V	0.874	0.90
12_N	50_L	0.872	0.90
426_E	429_G	0.872	0.90
299_E	302_Y	0.872	0.90
350_T	354_G	0.866	0.89
367_G	515_D	0.863	0.89
121_L	166_E	0.863	0.89
386_S	530_Y	0.862	0.89
438_D	442_F	0.860	0.89
402_F	426_E	0.860	0.89
141_L	188_P	0.858	0.89
80_S	132_H	0.856	0.89
391_A	463_V	0.854	0.89
202_A	210_H	0.847	0.88
17_I	250_S	0.846	0.88
463_V	472_Y	0.842	0.88
259_W	296_W	0.840	0.88
75_P	86_L	0.838	0.88
56_Q	114_D	0.834	0.88
356_L	360_P	0.833	0.88
342_F	528_F	0.832	0.87
16_S	77_L	0.830	0.87
368_H	378_A	0.829	0.87
7_V	17_I	0.829	0.87
24_Y	42_S	0.828	0.87
27_A	39_I	0.828	0.87
432_L	461_L	0.825	0.87
246_C	263_H	0.824	0.87
460_Y	478_K	0.823	0.87
332_E	527_Y	0.823	0.87
45_L	262_A	0.823	0.87
66_N	90_D	0.818	0.87
105_L	119_I	0.817	0.87
76_C	141_L	0.814	0.86
119_I	167_Q	0.810	0.86
320_E	323_F	0.808	0.86
73_W	92_K	0.806	0.86
52_A	56_Q	0.806	0.86
294_L	303_V	0.802	0.86
203_E	213_T	0.801	0.85
251_I	259_W	0.801	0.85
208_Y	283_C	0.800	0.85
472_Y	485_D	0.799	0.85
89_T	103_N	0.799	0.85
210_H	247_G	0.799	0.85
227_H	297_K	0.798	0.85
382_R	385_Q	0.798	0.85
153_S	184_L	0.793	0.85
196_Y	300_W	0.792	0.85
158_V	175_V	0.789	0.85
21_G	41_H	0.789	0.85
390_E	466_E	0.788	0.85
360_P	524_D	0.786	0.84
396_E	457_K	0.785	0.84
356_L	526_R	0.785	0.84
319_P	323_F	0.785	0.84
471_Y	485_D	0.783	0.84
142_N	173_P	0.780	0.84
49_H	323_F	0.777	0.84
87_I	130_L	0.776	0.84
72_V	89_T	0.774	0.83
260_Y	291_I	0.773	0.83
402_F	425_D	0.773	0.83
463_V	470_Y	0.772	0.83
220_I	223_P	0.772	0.83
76_C	189_H	0.772	0.83
231_P	234_T	0.769	0.83
219_N	223_P	0.766	0.83
19_R	254_T	0.766	0.83
217_S	222_G	0.763	0.83
227_H	232_I	0.763	0.83
193_I	196_Y	0.762	0.82
436_I	439_N	0.761	0.82
422_V	430_R	0.761	0.82
232_I	294_L	0.760	0.82
399_P	404_Q	0.759	0.82
449_K	453_P	0.758	0.82
68_N	411_Y	0.756	0.82
105_L	121_L	0.756	0.82
384_W	389_F	0.755	0.82
474_Y	481_W	0.755	0.82
470_Y	490_S	0.753	0.82
20_A	82_G	0.751	0.82
201_T	213_T	0.749	0.81
106_V	118_P	0.748	0.81
77_L	111_I	0.747	0.81
33_W	505_T	0.743	0.81
12_N	385_Q	0.743	0.81
365_L	378_A	0.743	0.81
258_E	317_S	0.741	0.81
196_Y	225_E	0.741	0.81
293_K	304_V	0.740	0.81
423_T	426_E	0.739	0.81
109_E	114_D	0.736	0.80
321_T	324_E	0.733	0.80
344_T	380_V	0.732	0.80
314_D	317_S	0.731	0.80
134_T	195_N	0.731	0.80
159_I	190_L	0.730	0.80
402_F	424_H	0.729	0.80
189_H	250_S	0.728	0.80
49_H	324_E	0.728	0.80
515_D	523_A	0.728	0.80
79_Y	82_G	0.726	0.79
90_D	101_C	0.726	0.79
200_L	294_L	0.726	0.79
233_L	303_V	0.722	0.79
139_Y	161_E	0.721	0.79
137_K	164_D	0.717	0.78
432_L	474_Y	0.715	0.78
344_T	354_G	0.715	0.78
87_I	128_A	0.715	0.78
371_L	409_V	0.715	0.78
195_N	218_A	0.714	0.78
304_V	307_K	0.713	0.78
80_S	138_K	0.713	0.78
122_N	168_K	0.711	0.78
446_L	450_I	0.710	0.78
40_H	187_A	0.710	0.78
131_F	220_I	0.710	0.78
131_F	138_K	0.709	0.78
329_E	341_N	0.709	0.78
434_L	438_D	0.707	0.78
315_A	318_I	0.706	0.77
379_F	508_F	0.706	0.77
460_Y	513_C	0.706	0.77
29_S	205_G	0.705	0.77
55_L	88_Y	0.705	0.77
343_Q	383_R	0.705	0.77
42_S	48_W	0.704	0.77
429_G	434_L	0.704	0.77
179_G	204_G	0.703	0.77
367_G	404_Q	0.703	0.77
261_L	292_Q	0.702	0.77
39_I	54_P	0.701	0.77
29_S	206_T	0.700	0.77
176_I	220_I	0.699	0.77
314_D	320_E	0.696	0.76
407_G	512_Q	0.695	0.76
35_P	286_G	0.695	0.76
19_R	252_V	0.695	0.76
3_I	291_I	0.691	0.76
92_K	102_H	0.691	0.76
103_N	125_G	0.689	0.76
333_F	363_L	0.686	0.75
333_F	342_F	0.686	0.75
522_P	526_R	0.685	0.75
389_F	410_N	0.684	0.75
366_F	524_D	0.684	0.75
143_M	154_F	0.684	0.75
424_H	429_G	0.684	0.75
313_V	318_I	0.683	0.75
107_T	167_Q	0.682	0.75
330_V	527_Y	0.681	0.75
446_L	451_V	0.680	0.75
158_V	173_P	0.680	0.75
448_N	482_H	0.678	0.75
431_I	437_C	0.676	0.74
157_I	203_E	0.675	0.74
164_D	167_Q	0.675	0.74
59_S	106_V	0.674	0.74
514_Q	517_S	0.674	0.74
139_Y	474_Y	0.673	0.74
402_F	517_S	0.672	0.74
4_T	312_E	0.671	0.74
19_R	23_D	0.670	0.74
160_Q	171_G	0.669	0.74
226_V	230_N	0.669	0.74
473_F	481_W	0.669	0.74
446_L	452_I	0.669	0.74
405_A	514_Q	0.667	0.73
356_L	362_H	0.666	0.73
30_T	343_Q	0.664	0.73
297_K	301_P	0.664	0.73
32_E	505_T	0.664	0.73
9_K	387_L	0.663	0.73
334_E	361_N	0.662	0.73
3_I	293_K	0.661	0.73
361_N	526_R	0.661	0.73
115_W	296_W	0.661	0.73
263_H	290_A	0.659	0.72
462_R	477_N	0.659	0.72
205_G	267_R	0.658	0.72
138_K	162_Y	0.657	0.72
212_A	215_A	0.657	0.72
34_F	348_P	0.657	0.72
248_H	264_L	0.656	0.72
362_H	396_E	0.654	0.72
8_L	12_N	0.654	0.72
38_Q	50_L	0.654	0.72
419_A	512_Q	0.652	0.72
355_S	366_F	0.650	0.71
51_V	340_I	0.649	0.71
355_S	524_D	0.648	0.71
264_L	288_E	0.648	0.71
72_V	75_P	0.647	0.71
420_L	472_Y	0.646	0.71
434_L	439_N	0.644	0.71
384_W	470_Y	0.644	0.71
170_I	173_P	0.643	0.71
227_H	302_Y	0.643	0.71
37_V	55_L	0.640	0.70
47_N	315_A	0.640	0.70
418_T	492_K	0.639	0.70
196_Y	299_E	0.639	0.70
14_D	74_A	0.637	0.70
25_Y	47_N	0.637	0.70
184_L	209_E	0.633	0.69
30_T	72_V	0.633	0.69
203_E	206_T	0.632	0.69
243_L	265_T	0.632	0.69
253_Q	258_E	0.631	0.69
388_H	467_K	0.630	0.69
306_G	310_S	0.629	0.69
450_I	484_I	0.629	0.69
232_I	261_L	0.629	0.69
24_Y	364_R	0.626	0.69
429_G	432_L	0.626	0.69
353_L	368_H	0.626	0.69
182_R	226_V	0.625	0.68
471_Y	484_I	0.624	0.68
14_D	29_S	0.624	0.68
314_D	318_I	0.623	0.68
255_H	318_I	0.622	0.68
235_S	263_H	0.621	0.68
465_I	509_V	0.621	0.68
159_I	174_K	0.621	0.68
235_S	246_C	0.620	0.68
324_E	327_Y	0.620	0.68
179_G	213_T	0.619	0.68
103_N	128_A	0.619	0.68
130_L	140_L	0.618	0.68
448_N	451_V	0.617	0.67
405_A	435_T	0.616	0.67
256_T	317_S	0.616	0.67
306_G	309_G	0.615	0.67
144_L	155_G	0.614	0.67
408_L	510_G	0.614	0.67
177_F	181_D	0.613	0.67
355_S	522_P	0.611	0.67
400_E	521_I	0.610	0.67
45_L	291_I	0.607	0.66
245_K	412_Y	0.606	0.66
63_M	66_N	0.605	0.66
432_L	436_I	0.604	0.66
90_D	100_D	0.604	0.66
393_T	396_E	0.604	0.66
433_E	436_I	0.603	0.66
200_L	301_P	0.603	0.66
120_K	123_S	0.603	0.66
76_C	250_S	0.603	0.66
108_C	116_S	0.603	0.66
462_R	475_S	0.602	0.66
156_G	175_V	0.602	0.66
338_L	354_G	0.602	0.66
248_H	288_E	0.601	0.65
13_P	28_V	0.601	0.65
474_Y	482_H	0.601	0.65
55_L	89_T	0.600	0.65
331_D	335_D	0.599	0.65
430_R	456_V	0.599	0.65
137_K	170_I	0.598	0.65
353_L	378_A	0.598	0.65
249_A	262_A	0.597	0.65
101_C	120_K	0.597	0.65
352_E	366_F	0.596	0.65
285_L	387_L	0.596	0.65
255_H	258_E	0.596	0.65
177_F	185_T	0.595	0.65
27_A	115_W	0.593	0.64
16_S	28_V	0.592	0.64
313_V	317_S	0.591	0.64
430_R	457_K	0.591	0.64
437_C	442_F	0.591	0.64
19_R	257_D	0.590	0.64
107_T	118_P	0.590	0.64
176_I	201_T	0.589	0.64
359_A	526_R	0.587	0.64
408_L	472_Y	0.585	0.63
83_K	108_C	0.584	0.63
129_S	189_H	0.582	0.63
39_I	52_A	0.581	0.63
509_V	528_F	0.580	0.63
402_F	423_T	0.580	0.63
311_L	315_A	0.579	0.63
81_D	84_F	0.579	0.63
73_W	184_L	0.578	0.62
384_W	465_I	0.577	0.62
7_V	291_I	0.577	0.62
395_V	523_A	0.576	0.62
179_G	203_E	0.575	0.62
90_D	102_H	0.575	0.62
319_P	324_E	0.575	0.62
267_R	288_E	0.574	0.62
223_P	380_V	0.573	0.62
396_E	524_D	0.573	0.62
330_V	394_A	0.572	0.62
103_N	140_L	0.571	0.62
31_F	35_P	0.568	0.61
404_Q	521_I	0.566	0.61
9_K	288_E	0.566	0.61
204_G	213_T	0.566	0.61
344_T	347_I	0.565	0.61
405_A	423_T	0.565	0.61
23_D	51_V	0.564	0.61
226_V	231_P	0.564	0.61
458_Y	477_N	0.564	0.61
169_L	172_K	0.563	0.60
138_K	141_L	0.563	0.60
188_P	204_G	0.562	0.60
517_S	521_I	0.562	0.60
430_R	434_L	0.562	0.60
202_A	249_A	0.562	0.60
432_L	439_N	0.561	0.60
477_N	481_W	0.561	0.60
410_N	509_V	0.560	0.60
155_G	177_F	0.559	0.60
199_L	247_G	0.558	0.60
198_Y	300_W	0.558	0.60
408_L	528_F	0.558	0.60
326_T	329_E	0.558	0.60
48_W	197_Y	0.557	0.60
472_Y	490_S	0.557	0.60
330_V	333_F	0.557	0.60
402_F	518_G	0.556	0.59
367_G	513_C	0.556	0.59
452_I	476_F	0.555	0.59
420_L	461_L	0.555	0.59
362_H	394_A	0.554	0.59
14_D	287_R	0.553	0.59
390_E	473_F	0.552	0.59
207_R	245_K	0.552	0.59
239_P	244_Q	0.552	0.59
227_H	230_N	0.552	0.59
205_G	210_H	0.552	0.59
30_T	79_Y	0.551	0.59
32_E	68_N	0.550	0.59
214_I	227_H	0.548	0.58
157_I	188_P	0.547	0.58
232_I	235_S	0.545	0.58
41_H	50_L	0.545	0.58
208_Y	245_K	0.544	0.58
187_A	212_A	0.543	0.58
490_S	507_A	0.542	0.58
511_M	528_F	0.542	0.58
459_V	476_F	0.541	0.57
88_Y	104_Y	0.540	0.57
30_T	35_P	0.540	0.57
453_P	457_K	0.539	0.57
39_I	112_N	0.538	0.57
447_N	450_I	0.538	0.57
317_S	322_I	0.538	0.57
204_G	210_H	0.538	0.57
73_W	88_Y	0.538	0.57
418_T	470_Y	0.538	0.57
137_K	220_I	0.537	0.57
471_Y	486_I	0.537	0.57
338_L	363_L	0.536	0.57
408_L	509_V	0.535	0.57
17_I	45_L	0.535	0.57
448_N	484_I	0.535	0.57
382_R	386_S	0.535	0.57
103_N	126_F	0.534	0.56
431_I	434_L	0.534	0.56
397_F	406_A	0.533	0.56
354_G	357_T	0.533	0.56
420_L	470_Y	0.532	0.56
235_S	290_A	0.531	0.56
256_T	318_I	0.531	0.56
303_V	310_S	0.531	0.56
206_T	247_G	0.529	0.56
195_N	299_E	0.529	0.56
432_L	435_T	0.529	0.56
108_C	169_L	0.528	0.56
16_S	248_H	0.528	0.56
450_I	461_L	0.528	0.56
303_V	307_K	0.527	0.55
140_L	169_L	0.527	0.55
296_W	300_W	0.527	0.55
338_L	342_F	0.527	0.55
331_D	526_R	0.527	0.55
408_L	420_L	0.526	0.55
476_F	479_E	0.526	0.55
87_I	189_H	0.526	0.55
24_Y	430_R	0.525	0.55
315_A	319_P	0.525	0.55
369_E	375_F	0.525	0.55
121_L	162_Y	0.524	0.55
89_T	124_S	0.523	0.55
287_R	296_W	0.523	0.55
395_V	464_N	0.522	0.55
317_S	320_E	0.522	0.55
344_T	349_F	0.521	0.55
323_F	326_T	0.520	0.54
36_G	115_W	0.520	0.54
345_L	381_A	0.519	0.54
486_I	491_K	0.519	0.54
447_N	451_V	0.519	0.54
376_T	380_V	0.519	0.54
337_T	451_V	0.517	0.54
337_T	360_P	0.517	0.54
181_D	226_V	0.517	0.54
335_D	358_Q	0.517	0.54
129_S	142_N	0.516	0.54
41_H	252_V	0.516	0.54
399_P	423_T	0.516	0.54
18_C	77_L	0.516	0.54
199_L	203_E	0.515	0.54
210_H	264_L	0.514	0.54
75_P	79_Y	0.514	0.54
331_D	338_L	0.514	0.54
72_V	86_L	0.513	0.54
414_T	491_K	0.513	0.54
202_A	206_T	0.513	0.54
200_L	251_I	0.512	0.53
78_S	250_S	0.512	0.53
15_P	75_P	0.511	0.53
477_N	482_H	0.510	0.53
176_I	226_V	0.510	0.53
419_A	514_Q	0.510	0.53
221_E	224_Y	0.509	0.53
354_G	365_L	0.509	0.53
124_S	142_N	0.508	0.53
450_I	456_V	0.508	0.53
141_L	220_I	0.507	0.53
16_S	40_H	0.506	0.53
126_F	184_L	0.506	0.53
126_F	188_P	0.506	0.53
25_Y	51_V	0.506	0.53
206_T	210_H	0.506	0.53
373_S	409_V	0.506	0.53
223_P	300_W	0.504	0.52
143_M	158_V	0.504	0.52
399_P	523_A	0.504	0.52
125_G	202_A	0.503	0.52
51_V	111_I	0.502	0.52
349_F	353_L	0.502	0.52
171_G	176_I	0.501	0.52
295_Y	305_G	0.500	0.52
363_L	407_G	0.500	0.52

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3c2uA	3	1	100	0.152	Contact Map
1yifA	3	0.9981	100	0.156	Contact Map
2exhA	3	0.9981	100	0.162	Contact Map
1yrzA	1	0.9737	100	0.168	Contact Map
3zxkA	1	0.9024	100	0.256	Contact Map
4kc7A	1	0.6942	100	0.488	Contact Map
2x8sA	1	0.6904	100	0.493	Contact Map
4kcaA	2	0.7336	100	0.494	Contact Map
3c7fA	1	0.7917	100	0.516	Contact Map
3akhA	1	0.7786	100	0.52	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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