GREMLIN Database
YNAD - Uncharacterized N-acetyltransferase YnaD
UniProt: P94482 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 170 (161)
Sequences: 19802 (15182)
Seq/√Len: 1196.5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
122_A135_M2.7471.00
101_S137_K2.7081.00
11_R62_I2.7081.00
63_L66_E2.4371.00
11_R17_D2.3841.00
143_E163_A2.2661.00
84_Y117_L2.2131.00
4_T64_R2.2041.00
7_R102_E2.1261.00
29_N92_P2.1171.00
124_C132_Y2.0961.00
75_F111_G2.0931.00
142_R145_F2.0751.00
142_R160_Y2.0061.00
5_T106_A1.9551.00
133_R136_K1.9381.00
124_C135_M1.9381.00
132_Y136_K1.8901.00
109_E113_K1.8431.00
5_T102_E1.8021.00
60_P69_L1.7481.00
27_D92_P1.7431.00
118_H148_K1.7401.00
86_I104_A1.7211.00
108_L140_M1.6861.00
13_F60_P1.6771.00
108_L120_I1.6671.00
19_Q41_E1.6261.00
145_F160_Y1.6011.00
20_A69_L1.5891.00
91_N94_Y1.5731.00
104_A138_I1.5561.00
62_I67_D1.5491.00
9_L64_R1.5461.00
41_E45_K1.5451.00
18_W45_K1.5441.00
132_Y142_R1.5371.00
73_I103_A1.5201.00
106_A109_E1.4961.00
126_P158_D1.4851.00
132_Y160_Y1.4451.00
151_P156_W1.4421.00
90_F100_A1.4201.00
136_K142_R1.4091.00
15_F49_N1.3721.00
118_H156_W1.3571.00
47_F51_N1.3521.00
129_I132_Y1.3451.00
40_T43_D1.3441.00
61_V90_F1.3191.00
101_S134_V1.3091.00
88_W135_M1.2961.00
61_V103_A1.2841.00
70_I94_Y1.2361.00
111_G120_I1.2301.00
132_Y162_Y1.2291.00
126_P145_F1.2261.00
20_A68_C1.2181.00
9_L62_I1.2011.00
149_C159_E1.1921.00
73_I107_I1.1901.00
63_L70_I1.1851.00
119_R163_A1.1821.00
110_Y114_E1.1791.00
4_T9_L1.1791.00
127_E157_W1.1761.00
63_L99_Y1.1661.00
68_C93_N1.1371.00
146_F161_Y1.1131.00
5_T8_L1.1061.00
88_W131_S1.1061.00
45_K49_N1.1061.00
85_E123_T1.1021.00
72_H89_V1.0941.00
111_G115_M1.0771.00
22_Y41_E1.0591.00
100_A134_V1.0541.00
68_C94_Y1.0531.00
18_W48_V1.0391.00
36_E39_F1.0381.00
110_Y115_M1.0361.00
147_K163_A1.0301.00
131_S135_M1.0281.00
92_P95_Q1.0241.00
119_R143_E1.0231.00
18_W41_E1.0221.00
95_Q130_P1.0161.00
24_Y89_V1.0151.00
124_C162_Y1.0101.00
148_K158_D1.0101.00
20_A23_E0.9951.00
145_F158_D0.9891.00
147_K158_D0.9891.00
15_F45_K0.9781.00
24_Y91_N0.9751.00
83_T121_I0.9701.00
59_F110_Y0.9641.00
142_R162_Y0.9591.00
59_F107_I0.9561.00
122_A140_M0.9511.00
46_A50_K0.9481.00
108_L164_I0.9381.00
63_L97_K0.9331.00
63_L68_C0.9271.00
134_V138_I0.9181.00
135_M140_M0.9171.00
101_S105_Q0.9061.00
125_Q157_W0.9041.00
75_F107_I0.9031.00
108_L138_I0.9011.00
29_N32_K0.8951.00
140_M164_I0.8921.00
22_Y26_S0.8901.00
129_I133_R0.8791.00
39_F44_A0.8721.00
111_G117_L0.8701.00
105_Q109_E0.8621.00
30_V95_Q0.8521.00
90_F99_Y0.8481.00
62_I69_L0.8471.00
27_D91_N0.8471.00
23_E91_N0.8471.00
126_P160_Y0.8421.00
101_S138_I0.8421.00
82_H156_W0.8381.00
13_F72_H0.8371.00
8_L103_A0.8321.00
96_N130_P0.8261.00
9_L67_D0.8251.00
83_T119_R0.8251.00
8_L99_Y0.8151.00
88_W100_A0.8121.00
17_D62_I0.8101.00
68_C91_N0.8041.00
18_W22_Y0.8041.00
102_E106_A0.8041.00
143_E147_K0.7971.00
27_D93_N0.7961.00
105_Q138_I0.7961.00
15_F18_W0.7931.00
83_T149_C0.7901.00
82_H151_P0.7781.00
22_Y44_A0.7771.00
19_Q23_E0.7751.00
146_F149_C0.7701.00
148_K156_W0.7661.00
23_E68_C0.7641.00
94_Y97_K0.7631.00
29_N95_Q0.7591.00
129_I136_K0.7551.00
63_L94_Y0.7541.00
136_K162_Y0.7531.00
42_E45_K0.7511.00
124_C131_S0.7391.00
124_C160_Y0.7231.00
104_A134_V0.7201.00
123_T146_F0.7131.00
23_E93_N0.7111.00
41_E44_A0.7091.00
96_N101_S0.7081.00
85_E121_I0.7061.00
5_T10_I0.7051.00
20_A91_N0.7021.00
151_P155_E0.6981.00
25_T89_V0.6881.00
42_E46_A0.6841.00
46_A49_N0.6781.00
33_Y125_Q0.6771.00
43_D46_A0.6761.00
31_M34_I0.6701.00
122_A131_S0.6681.00
11_R60_P0.6671.00
88_W104_A0.6651.00
70_I99_Y0.6621.00
40_T44_A0.6551.00
101_S130_P0.6551.00
100_A104_A0.6531.00
61_V73_I0.6501.00
127_E155_E0.6501.00
96_N133_R0.6481.00
112_F164_I0.6421.00
123_T159_E0.6421.00
133_R137_K0.6411.00
7_R98_G0.6391.00
61_V99_Y0.6361.00
24_Y69_L0.6351.00
6_K102_E0.6341.00
33_Y127_E0.6281.00
84_Y111_G0.6231.00
99_Y102_E0.6221.00
23_E27_D0.6201.00
58_K74_V0.6171.00
27_D95_Q0.6151.00
88_W134_V0.6111.00
152_K155_E0.6091.00
75_F84_Y0.6051.00
34_I89_V0.5921.00
82_H118_H0.5911.00
130_P133_R0.5901.00
135_M162_Y0.5891.00
96_N134_V0.5871.00
138_I164_I0.5871.00
126_P132_Y0.5861.00
61_V71_G0.5851.00
11_R14_E0.5781.00
90_F95_Q0.5781.00
119_R149_C0.5771.00
90_F94_Y0.5761.00
8_L102_E0.5701.00
151_P154_N0.5691.00
73_I104_A0.5681.00
14_E17_D0.5651.00
150_I159_E0.5621.00
44_A47_F0.5591.00
13_F21_V0.5571.00
141_R147_K0.5521.00
108_L112_F0.5491.00
104_A140_M0.5481.00
123_T161_Y0.5411.00
122_A162_Y0.5391.00
121_I149_C0.5381.00
21_V72_H0.5381.00
30_V89_V0.5341.00
69_L72_H0.5301.00
152_K157_W0.5291.00
144_G163_A0.5241.00
144_G147_K0.5221.00
8_L106_A0.5191.00
121_I146_F0.5171.00
19_Q22_Y0.5161.00
76_Y85_E0.5161.00
84_Y120_I0.5161.00
25_T72_H0.5131.00
70_I91_N0.5061.00
25_T39_F0.5061.00
20_A62_I0.5061.00
51_N58_K0.5061.00
18_W44_A0.5051.00
109_E114_E0.5051.00
86_I120_I0.5021.00
120_I140_M0.5011.00
44_A48_V0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3fbuA 2 0.9824 100 0.288 Contact Map
2vzyA 3 0.8941 100 0.294 Contact Map
3pzjA 2 0.9941 100 0.296 Contact Map
1yreA 2 0.9529 100 0.306 Contact Map
3r9fA 1 0.9647 100 0.318 Contact Map
2fckA 2 0.9647 100 0.321 Contact Map
2z10A 2 0.9824 100 0.324 Contact Map
3igrA 2 1 100 0.326 Contact Map
1nslA 3 0.9824 100 0.329 Contact Map
3tcvA 2 1 100 0.346 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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