GREMLIN Database
YNBB - Uncharacterized protein YnbB
UniProt: P94479 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 421 (406)
Sequences: 895 (503)
Seq/√Len: 25.0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
46_K76_D4.8961.00
358_Y365_D4.2381.00
79_G222_H4.1691.00
297_G404_V4.0831.00
82_A268_R3.7431.00
39_R222_H3.7351.00
19_E401_Y3.6281.00
17_E307_K3.5361.00
80_G221_C3.4091.00
110_L169_V3.2901.00
154_I159_V3.1981.00
193_I225_A3.1171.00
47_H76_D3.1121.00
250_K253_W3.0691.00
197_K205_V3.0251.00
109_E167_T2.9931.00
33_S292_S2.9451.00
311_T328_E2.8931.00
49_V69_T2.8591.00
89_I98_I2.7500.99
186_I190_K2.7080.99
228_M248_V2.6350.99
70_L281_Y2.6230.99
103_V227_L2.5180.99
190_K194_R2.5040.99
49_V73_I2.4450.99
29_I299_V2.4430.99
190_K218_L2.4380.99
77_V284_F2.4160.98
21_D303_R2.3930.98
200_N203_L2.3070.98
123_E128_R2.2630.98
331_D334_K2.2230.97
23_A27_K2.2150.97
341_A407_A2.2130.97
183_S321_T2.1910.97
336_I367_I2.1520.97
144_N162_A2.1320.96
122_E128_R2.0910.96
158_A162_A2.0770.96
42_Q46_K2.0740.96
289_H293_Q2.0270.95
47_H72_S2.0180.95
53_H69_T2.0080.95
49_V348_I2.0050.95
21_D307_K1.9810.95
154_I192_M1.9760.95
156_Y195_F1.9650.94
214_F236_P1.9560.94
112_Y171_G1.9510.94
332_R365_D1.9510.94
116_K122_E1.9380.94
109_E144_N1.9370.94
153_K188_E1.9230.94
172_I189_I1.9200.94
254_I257_C1.9200.94
335_M385_G1.9190.94
105_R139_F1.8960.93
329_F393_A1.8440.92
116_K145_A1.8440.92
49_V281_Y1.8440.92
163_I200_N1.8340.92
15_A409_C1.8290.92
35_R217_E1.8000.91
29_I292_S1.7500.90
25_I28_Q1.7480.90
71_E89_I1.7430.90
239_G399_L1.7410.90
301_T395_V1.7110.89
79_G221_C1.6950.88
300_F408_I1.6950.88
20_A23_A1.6580.87
114_T154_I1.6570.87
74_Y78_F1.6410.87
70_L280_M1.6350.87
306_E316_W1.6210.86
30_E296_K1.6200.86
186_I218_L1.6060.86
247_L257_C1.5920.85
15_A300_F1.5890.85
99_A227_L1.5870.85
105_R134_G1.5850.85
186_I223_V1.5810.85
91_S263_S1.5710.84
82_A251_A1.5580.84
305_L411_A1.5500.83
22_I26_H1.5310.83
163_I167_T1.5240.82
103_V169_V1.5210.82
277_L280_M1.5190.82
32_I295_L1.5130.82
96_I206_F1.5030.81
33_S402_S1.4970.81
155_D158_A1.4860.81
207_V225_A1.4860.81
332_R387_I1.4860.81
364_D388_R1.4730.80
242_K279_E1.4560.79
158_A161_A1.4560.79
83_G248_V1.4550.79
34_E402_S1.4480.79
109_E142_G1.4360.78
33_S293_Q1.4310.78
103_V256_A1.4300.78
68_D273_S1.4270.78
335_M393_A1.4250.78
247_L254_I1.4170.77
206_F229_A1.4160.77
169_V204_I1.4010.77
47_H73_I1.3980.76
339_C393_A1.3960.76
62_Y378_S1.3930.76
186_I216_E1.3930.76
195_F199_I1.3890.76
336_I356_P1.3850.76
218_L223_V1.3720.75
195_F198_E1.3690.75
106_P139_F1.3300.73
16_M31_E1.3260.72
18_V307_K1.3170.72
180_N392_V1.3080.71
184_F192_M1.3070.71
215_V295_L1.3030.71
114_T192_M1.2970.71
30_E292_S1.2890.70
109_E164_N1.2840.70
113_I192_M1.2830.70
379_I382_S1.2790.70
216_E321_T1.2740.69
324_I383_A1.2710.69
370_A378_S1.2640.69
113_I159_V1.2570.68
160_A199_I1.2560.68
82_A254_I1.2510.68
109_E163_I1.2430.67
104_L110_L1.2420.67
68_D281_Y1.2390.67
73_I281_Y1.2340.67
41_L406_N1.2340.67
306_E315_K1.2230.66
344_F414_S1.2220.66
221_C228_M1.2200.66
285_F347_P1.2180.66
242_K276_S1.2140.66
149_T158_A1.1930.64
293_Q400_T1.1930.64
15_A304_F1.1890.64
310_F334_K1.1870.64
290_V379_I1.1820.63
101_F105_R1.1500.61
48_K351_H1.1450.61
197_K203_L1.1050.58
99_A103_V1.1050.58
336_I387_I1.1030.58
131_E137_K1.1000.58
189_I212_G1.0970.58
225_A228_M1.0970.58
218_L222_H1.0950.57
123_E132_N1.0930.57
251_A255_E1.0920.57
91_S270_A1.0870.57
134_G138_D1.0830.57
289_H402_S1.0790.56
164_N167_T1.0770.56
87_P403_H1.0770.56
329_F334_K1.0700.56
105_R256_A1.0650.55
194_R198_E1.0640.55
80_G222_H1.0640.55
187_S216_E1.0600.55
293_Q402_S1.0490.54
273_S277_L1.0470.54
332_R391_Y1.0440.54
105_R138_D1.0440.54
308_L412_V1.0430.54
180_N328_E1.0410.54
78_F248_V1.0400.53
13_K17_E1.0360.53
90_I270_A1.0360.53
37_E403_H1.0340.53
184_F188_E1.0330.53
51_D375_Q1.0320.53
346_S372_T1.0260.52
163_I203_L1.0120.51
357_A365_D1.0100.51
187_S218_L1.0080.51
97_S101_F1.0080.51
282_Q374_I1.0020.51
71_E84_L1.0010.51
311_T315_K0.9990.51
31_E217_E0.9900.50
89_I95_A0.9860.50
68_D72_S0.9750.49
176_K183_S0.9730.49
28_Q319_K0.9720.49
269_E370_A0.9720.49
84_L258_S0.9670.48
69_T72_S0.9620.48
335_M387_I0.9590.48
191_E195_F0.9550.47
45_R345_A0.9540.47
192_M196_V0.9530.47
300_F304_F0.9500.47
111_L163_I0.9430.46
102_G257_C0.9380.46
277_L281_Y0.9360.46
113_I170_I0.9330.46
167_T200_N0.9330.46
133_A256_A0.9320.46
153_K254_I0.9280.45
141_I199_I0.9280.45
266_I270_A0.9270.45
129_G137_K0.9270.45
345_A407_A0.9250.45
303_R316_W0.9250.45
341_A345_A0.9240.45
109_E166_K0.9230.45
156_Y192_M0.9200.45
123_E129_G0.9180.45
320_R325_Q0.9110.44
87_P277_L0.9100.44
41_L364_D0.9090.44
69_T281_Y0.9030.44
192_M205_V0.9020.44
298_A325_Q0.8990.43
146_V158_A0.8980.43
160_A198_E0.8980.43
45_R410_S0.8900.43
99_A257_C0.8870.42
206_F321_T0.8840.42
242_K280_M0.8840.42
160_A195_F0.8820.42
156_Y191_E0.8810.42
71_E98_I0.8760.42
285_F403_H0.8740.42
410_S413_D0.8740.42
204_I247_L0.8720.41
301_T305_L0.8690.41
71_E272_A0.8680.41
139_F260_R0.8650.41
52_T351_H0.8620.41
114_T205_V0.8620.41
98_I261_M0.8600.41
39_R43_S0.8580.40
90_I262_T0.8580.40
226_D250_K0.8540.40
166_K200_N0.8530.40
330_S389_P0.8520.40
105_R260_R0.8470.40
78_F236_P0.8470.40
44_Y49_V0.8460.40
31_E35_R0.8450.40
336_I340_Q0.8430.39
159_V192_M0.8410.39
306_E317_D0.8410.39
121_L236_P0.8380.39
152_G182_P0.8350.39
99_A247_L0.8320.39
45_R350_A0.8310.39
149_T152_G0.8280.38
70_L277_L0.8250.38
101_F134_G0.8240.38
269_E378_S0.8180.38
305_L327_V0.8180.38
342_I370_A0.8180.38
169_V203_L0.8170.38
263_S266_I0.8150.37
375_Q378_S0.8130.37
168_K367_I0.8130.37
157_D160_A0.8130.37
19_E405_K0.8120.37
349_N352_V0.8110.37
340_Q353_T0.8100.37
22_I303_R0.8090.37
300_F409_C0.8000.36
139_F256_A0.7980.36
116_K143_Y0.7950.36
243_T274_L0.7940.36
32_I36_N0.7930.36
103_V139_F0.7930.36
27_K348_I0.7920.36
113_I172_I0.7870.36
103_V250_K0.7840.35
108_D168_K0.7840.35
56_P277_L0.7810.35
18_V22_I0.7800.35
339_C347_P0.7770.35
172_I193_I0.7760.35
103_V257_C0.7760.35
340_Q355_Y0.7760.35
54_F280_M0.7720.35
36_N39_R0.7710.35
366_V387_I0.7680.34
56_P275_Y0.7670.34
54_F275_Y0.7670.34
56_P272_A0.7670.34
337_A340_Q0.7640.34
111_L164_N0.7640.34
38_W42_Q0.7590.34
138_D225_A0.7570.34
29_I295_L0.7550.33
14_T18_V0.7550.33
142_G167_T0.7520.33
83_G221_C0.7510.33
359_M368_M0.7480.33
187_S201_E0.7480.33
128_R363_E0.7480.33
102_G105_R0.7480.33
123_E127_V0.7470.33
88_Q272_A0.7450.33
18_V21_D0.7440.33
185_L321_T0.7410.33
274_L277_L0.7410.33
87_P273_S0.7390.32
261_M284_F0.7380.32
327_V395_V0.7370.32
229_A293_Q0.7370.32
176_K313_N0.7360.32
282_Q286_L0.7360.32
102_G106_P0.7360.32
98_I257_C0.7360.32
240_L335_M0.7350.32
331_D392_V0.7350.32
227_L257_C0.7350.32
286_L400_T0.7350.32
365_D391_Y0.7340.32
370_A400_T0.7320.32
372_T377_A0.7310.32
110_L171_G0.7270.32
14_T304_F0.7270.32
72_S76_D0.7260.32
310_F341_A0.7260.32
304_F412_V0.7250.32
125_V145_A0.7230.31
129_G132_N0.7230.31
58_T254_I0.7210.31
91_S266_I0.7210.31
53_H238_G0.7200.31
206_F227_L0.7190.31
341_A411_A0.7190.31
363_E388_R0.7180.31
204_I250_K0.7180.31
109_E162_A0.7180.31
194_R218_L0.7170.31
338_F395_V0.7160.31
300_F411_A0.7130.31
93_T219_E0.7130.31
335_M357_A0.7120.31
53_H102_G0.7120.31
18_V300_F0.7110.31
28_Q332_R0.7100.31
328_E392_V0.7060.30
52_T65_I0.7050.30
254_I268_R0.7040.30
169_V229_A0.7040.30
71_E268_R0.7020.30
17_E20_A0.7000.30
88_Q372_T0.6990.30
89_I182_P0.6970.30
214_F403_H0.6970.30
144_N164_N0.6960.30
97_S257_C0.6940.30
54_F348_I0.6940.30
311_T330_S0.6920.30
93_T263_S0.6920.30
170_I203_L0.6910.29
21_D316_W0.6910.29
356_P363_E0.6880.29
97_S263_S0.6860.29
142_G166_K0.6860.29
205_V250_K0.6860.29
69_T238_G0.6850.29
160_A165_P0.6840.29
227_L253_W0.6770.29
86_R265_G0.6770.29
286_L290_V0.6770.29
172_I192_M0.6760.29
233_I378_S0.6750.29
22_I299_V0.6700.28
43_S76_D0.6680.28
168_K311_T0.6680.28
106_P260_R0.6670.28
102_G254_I0.6660.28
182_P313_N0.6650.28
134_G260_R0.6650.28
156_Y199_I0.6640.28
324_I370_A0.6640.28
272_A277_L0.6630.28
113_I205_V0.6630.28
204_I253_W0.6620.28
179_A305_L0.6590.28
74_Y248_V0.6540.27
55_T273_S0.6540.27
30_E394_Y0.6490.27
165_P200_N0.6490.27
136_L141_I0.6460.27
252_K256_A0.6450.27
87_P276_S0.6450.27
180_N385_G0.6430.27
53_H106_P0.6430.27
157_D190_K0.6430.27
37_E400_T0.6430.27
170_I196_V0.6410.27
378_S400_T0.6410.27
385_G407_A0.6400.26
29_I32_I0.6380.26
328_E385_G0.6380.26
149_T155_D0.6380.26
196_V205_V0.6370.26
11_L18_V0.6370.26
129_G394_Y0.6360.26
182_P318_A0.6340.26
167_T203_L0.6330.26
276_S279_E0.6310.26
123_E385_G0.6310.26
53_H73_I0.6290.26
74_Y240_L0.6270.26
323_L404_V0.6270.26
27_K141_I0.6240.26
194_R377_A0.6230.26
305_L412_V0.6210.25
98_I374_I0.6190.25
11_L409_C0.6190.25
102_G134_G0.6170.25
28_Q31_E0.6170.25
323_L335_M0.6170.25
89_I128_R0.6160.25
372_T407_A0.6140.25
88_Q310_F0.6110.25
385_G389_P0.6110.25
42_Q45_R0.6110.25
313_N318_A0.6090.25
72_S247_L0.6090.25
176_K395_V0.6080.25
17_E194_R0.6080.25
97_S264_P0.6070.25
75_A83_G0.6050.25
342_I407_A0.6040.25
303_R307_K0.6040.25
39_R341_A0.6030.24
54_F272_A0.6030.24
323_L395_V0.6020.24
99_A171_G0.6000.24
193_I203_L0.6000.24
62_Y360_P0.5990.24
215_V291_V0.5990.24
114_T159_V0.5980.24
78_F214_F0.5980.24
146_V162_A0.5970.24
79_G340_Q0.5960.24
149_T153_K0.5960.24
273_S312_S0.5960.24
74_Y163_I0.5960.24
132_N135_S0.5950.24
176_K321_T0.5950.24
73_I348_I0.5940.24
240_L243_T0.5930.24
112_Y351_H0.5920.24
30_E293_Q0.5910.24
370_A381_L0.5900.24
18_V303_R0.5900.24
150_K342_I0.5880.24
292_S402_S0.5880.24
276_S280_M0.5860.24
365_D387_I0.5850.24
149_T227_L0.5850.24
168_K256_A0.5830.23
68_D97_S0.5820.23
298_A301_T0.5810.23
239_G400_T0.5810.23
197_K201_E0.5810.23
270_A357_A0.5800.23
34_E407_A0.5800.23
62_Y367_I0.5790.23
215_V273_S0.5780.23
112_Y169_V0.5770.23
141_I165_P0.5770.23
112_Y192_M0.5760.23
32_I269_E0.5750.23
96_I374_I0.5750.23
165_P228_M0.5730.23
32_I217_E0.5730.23
125_V143_Y0.5730.23
253_W257_C0.5730.23
282_Q403_H0.5710.23
411_A415_L0.5700.23
176_K274_L0.5690.23
196_V199_I0.5680.23
14_T137_K0.5680.23
53_H372_T0.5670.23
82_A255_E0.5670.23
17_E21_D0.5660.23
146_V195_F0.5660.23
172_I223_V0.5660.23
171_G205_V0.5640.22
187_S191_E0.5640.22
80_G223_V0.5630.22
35_R350_A0.5610.22
46_K329_F0.5610.22
262_T270_A0.5600.22
171_G192_M0.5590.22
101_F106_P0.5580.22
188_E191_E0.5580.22
291_V375_Q0.5570.22
266_I366_V0.5570.22
236_P354_P0.5560.22
70_L272_A0.5560.22
54_F196_V0.5550.22
240_L374_I0.5550.22
364_D375_Q0.5550.22
52_T147_D0.5540.22
233_I360_P0.5520.22
245_G374_I0.5500.22
357_A378_S0.5500.22
39_R349_N0.5490.22
37_E297_G0.5470.22
174_R186_I0.5460.22
34_E38_W0.5460.22
289_H399_L0.5460.22
106_P141_I0.5460.22
77_V186_I0.5460.22
89_I245_G0.5450.21
102_G139_F0.5450.21
125_V336_I0.5440.21
51_D349_N0.5430.21
69_T193_I0.5420.21
187_S190_K0.5420.21
278_Q374_I0.5420.21
80_G254_I0.5420.21
34_E405_K0.5410.21
349_N359_M0.5410.21
37_E404_V0.5400.21
27_K198_E0.5390.21
297_G403_H0.5380.21
37_E405_K0.5380.21
133_A255_E0.5370.21
180_N313_N0.5370.21
183_S325_Q0.5360.21
102_G261_M0.5360.21
56_P293_Q0.5360.21
359_M370_A0.5350.21
372_T379_I0.5350.21
370_A383_A0.5340.21
258_S268_R0.5340.21
228_M284_F0.5340.21
103_V204_I0.5330.21
63_D258_S0.5320.21
103_V253_W0.5310.21
96_I159_V0.5300.21
138_D256_A0.5290.21
323_L379_I0.5290.21
297_G327_V0.5280.21
87_P98_I0.5280.21
331_D365_D0.5270.21
41_L347_P0.5270.21
39_R197_K0.5270.21
17_E35_R0.5260.21
111_L146_V0.5250.21
349_N395_V0.5250.21
63_D349_N0.5250.21
17_E365_D0.5240.20
123_E135_S0.5240.20
346_S407_A0.5230.20
190_K250_K0.5230.20
12_K15_A0.5230.20
20_A24_G0.5230.20
233_I238_G0.5230.20
368_M404_V0.5220.20
11_L407_A0.5210.20
295_L299_V0.5200.20
241_A324_I0.5200.20
96_I321_T0.5190.20
46_K150_K0.5190.20
190_K223_V0.5180.20
261_M268_R0.5170.20
214_F342_I0.5170.20
330_S334_K0.5170.20
101_F260_R0.5160.20
122_E241_A0.5150.20
221_C355_Y0.5150.20
18_V308_L0.5120.20
16_M20_A0.5110.20
17_E251_A0.5090.20
171_G206_F0.5090.20
14_T412_V0.5080.20
11_L300_F0.5080.20
282_Q394_Y0.5080.20
25_I299_V0.5080.20
56_P270_A0.5070.20
307_K385_G0.5070.20
275_Y279_E0.5070.20
95_A339_C0.5060.20
377_A382_S0.5060.20
16_M24_G0.5060.20
193_I197_K0.5060.20
400_T403_H0.5040.20
54_F276_S0.5040.20
122_E364_D0.5030.20
253_W256_A0.5030.20
134_G139_F0.5030.20
239_G379_I0.5030.20
35_R405_K0.5030.20
146_V186_I0.5020.19
282_Q297_G0.5020.19
297_G323_L0.5020.19
312_S321_T0.5020.19
403_H412_V0.5020.19
218_L221_C0.5010.19
227_L247_L0.5000.19
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3ht4A 4 0.9881 100 0.58 Contact Map
3i16A 4 0.9881 100 0.589 Contact Map
3jzlA 4 0.962 100 0.594 Contact Map
3hvyA 4 0.981 100 0.616 Contact Map
3aczA 4 0.8527 99.8 0.91 Contact Map
1pffA 3 0.7197 99.7 0.912 Contact Map
3wcoA 2 0.7316 99.7 0.913 Contact Map
3wcnA 2 0.7482 99.7 0.914 Contact Map
1jg8A 4 0.7696 99.7 0.914 Contact Map
3qhxA 4 0.8195 99.7 0.914 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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