YEBA - BACSU - GREMLIN Contacts

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YEBA - Uncharacterized protein YebA

UniProt:	P94476	Sequences: MPHDDHKGSRLSLLLFYFLAFLLLWEWLRPLDSFTETKHTGFFSVFIGLTFLLTFFRMRWFVTVPFCVIFTLISIHILFYQGSIFDLSWVSSFLQDVYLNITLIQSGQWNDMIPSFRTLLFFVLLWLLVYLLHYWVIYQRRILFFFLMTVAYITILDTFTPYDATFAVIRIVLIGFFMLGLLYLERIKLMERITLPKTSVLKWFLPLSVLVLAATGFGLAAPKSEPAWPDPVPFLKKITHQDRVSAGESKIGYGNHDESLGGPFQQDATPVFTWQGKERTYFRVETKDTYTGKGWIETDTGMSYQLSNGKVENLWFDHKVATERRTVRVKVDKHYGYNHLMYPIGAETIQPKQAVSLEMNGNTEQISPISEQAGEIRNMGNYTVTYNSPVYKLDELRKVKVRKNSEEYTFSDRYMQLPDSLPERVRTLAIKLTQDHDNMFDKVKAVEDYLGSNAFTYETENVTIPKNDEDYVDQFLFETKMGYCDNFSSAMVVLLRSAGIPARWVKGYTSGEYKEAGNKNGSIYEVTNNNAHSWVEVYFPEQGWVTFEPTKGFTNPAQFTSSDTKDSGSDSSSSPKKAKEKQKEEKKQPQKEEKQKEKREPAVSKKPSASHTNAGAGLYAALAVLAVLLVAAVLLYVFRSLWIPVFAVRKLKRRSDQHAFFEAYGALLKQLKRKGLPKRDSETLRDYAKRIDEKYDIEDMSKLTLSYERALYRNEDSSALWNDSRELWENLIKRRWS	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	737 (650)
Sequences:	2138 (1934)
Seq/√Len:	75.9

BACSU - YEBA

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
682_E	690_R	9.764	1.00
492_V	535_V	8.034	1.00
492_V	502_A	7.528	1.00
284_V	341_M	5.420	1.00
458_E	481_M	5.087	1.00
495_L	537_V	4.476	1.00
443_V	537_V	4.203	1.00
685_R	708_E	4.165	1.00
288_D	298_T	4.025	1.00
270_P	525_E	3.793	1.00
491_M	549_P	3.711	1.00
417_L	493_V	3.667	1.00
491_M	535_V	3.577	1.00
491_M	495_L	3.490	1.00
424_R	473_D	3.418	1.00
446_V	495_L	3.373	1.00
397_R	441_D	3.362	1.00
424_R	477_F	3.239	1.00
664_Y	704_T	3.196	1.00
423_E	427_T	3.185	1.00
491_M	547_F	3.134	1.00
275_Q	328_R	3.104	1.00
329_V	382_Y	3.023	1.00
457_Y	484_C	2.870	1.00
539_F	547_F	2.847	1.00
326_T	383_T	2.833	1.00
456_T	481_M	2.827	1.00
443_V	495_L	2.813	1.00
446_V	491_M	2.795	1.00
429_A	498_A	2.729	1.00
456_T	487_F	2.638	1.00
272_F	282_F	2.602	1.00
291_T	294_G	2.597	1.00
327_V	386_Y	2.568	1.00
495_L	500_I	2.549	1.00
288_D	414_Y	2.549	1.00
500_I	537_V	2.509	1.00
495_L	535_V	2.475	1.00
428_L	494_L	2.418	1.00
443_V	491_M	2.408	1.00
48_G	52_L	2.394	1.00
494_L	498_A	2.354	1.00
327_V	343_P	2.347	1.00
457_Y	532_H	2.305	1.00
484_C	532_H	2.279	1.00
407_E	410_F	2.272	1.00
436_H	445_A	2.263	1.00
688_A	704_T	2.261	1.00
717_S	720_L	2.198	1.00
682_E	687_Y	2.197	1.00
449_Y	455_F	2.194	1.00
535_V	548_E	2.186	1.00
425_V	476_L	2.178	1.00
678_K	687_Y	2.177	1.00
425_V	493_V	2.169	1.00
443_V	547_F	2.168	1.00
628_L	632_A	2.158	1.00
438_N	441_D	2.157	1.00
257_D	504_W	2.140	1.00
484_C	550_T	2.137	1.00
417_L	497_S	2.131	1.00
343_P	548_E	2.131	1.00
392_K	395_E	2.131	1.00
491_M	537_V	2.127	1.00
429_A	494_L	2.116	1.00
474_Q	478_E	2.090	1.00
424_R	478_E	2.087	1.00
664_Y	684_L	2.078	1.00
422_P	473_D	2.065	1.00
668_L	678_K	2.062	1.00
432_L	446_V	2.055	1.00
450_L	455_F	2.053	1.00
283_R	536_E	2.051	1.00
446_V	494_L	2.014	1.00
444_K	447_E	2.014	1.00
535_V	549_P	2.011	1.00
326_T	385_T	1.983	1.00
272_F	526_V	1.976	1.00
206_P	210_L	1.972	1.00
439_M	442_K	1.970	1.00
440_F	539_F	1.953	1.00
328_R	383_T	1.948	1.00
691_I	700_M	1.937	1.00
677_P	687_Y	1.934	1.00
471_Y	486_N	1.929	1.00
325_R	386_Y	1.924	1.00
440_F	547_F	1.922	1.00
282_F	343_P	1.889	1.00
671_L	691_I	1.880	1.00
287_K	506_K	1.874	1.00
415_M	499_G	1.873	1.00
422_P	425_V	1.869	1.00
274_W	282_F	1.860	1.00
429_A	497_S	1.846	1.00
513_Y	524_Y	1.828	1.00
447_E	548_E	1.824	1.00
494_L	497_S	1.817	1.00
664_Y	668_L	1.800	1.00
433_T	442_K	1.795	1.00
678_K	682_E	1.786	1.00
267_D	528_N	1.784	1.00
210_L	225_E	1.783	1.00
218_G	223_K	1.778	1.00
428_L	477_F	1.771	1.00
287_K	504_W	1.766	1.00
639_R	643_I	1.736	1.00
635_L	639_R	1.724	1.00
724_S	728_W	1.715	1.00
537_V	547_F	1.710	1.00
527_T	530_N	1.704	1.00
204_F	208_S	1.693	1.00
625_L	629_L	1.690	1.00
710_A	713_R	1.688	1.00
679_R	682_E	1.683	1.00
538_Y	543_G	1.679	1.00
270_P	527_T	1.677	1.00
704_T	708_E	1.676	1.00
429_A	433_T	1.669	1.00
443_V	446_V	1.666	1.00
457_Y	550_T	1.662	1.00
626_A	629_L	1.661	1.00
428_L	449_Y	1.656	1.00
624_V	627_V	1.656	1.00
448_D	452_S	1.655	1.00
723_D	727_L	1.649	1.00
443_V	500_I	1.649	1.00
270_P	273_T	1.648	1.00
283_R	505_V	1.643	1.00
288_D	413_R	1.641	1.00
455_F	480_K	1.638	1.00
465_P	474_Q	1.607	1.00
273_T	332_D	1.593	0.99
428_L	432_L	1.589	0.99
210_L	218_G	1.583	0.99
295_W	489_S	1.579	0.99
504_W	533_S	1.574	0.99
488_S	504_W	1.568	0.99
458_E	461_N	1.562	0.99
211_V	218_G	1.559	0.99
474_Q	479_T	1.559	0.99
483_Y	486_N	1.557	0.99
253_Y	284_V	1.550	0.99
432_L	494_L	1.546	0.99
108_Q	112_M	1.544	0.99
71_T	126_W	1.542	0.99
283_R	286_T	1.540	0.99
346_A	386_Y	1.535	0.99
457_Y	483_Y	1.532	0.99
328_R	381_N	1.529	0.99
485_D	504_W	1.522	0.99
459_T	484_C	1.519	0.99
424_R	428_L	1.513	0.99
109_W	112_M	1.510	0.99
667_L	700_M	1.498	0.99
251_I	266_Q	1.494	0.99
447_E	549_P	1.488	0.99
473_D	477_F	1.485	0.99
253_Y	341_M	1.474	0.99
291_T	296_I	1.460	0.99
427_T	431_K	1.453	0.99
471_Y	483_Y	1.444	0.99
646_F	650_K	1.437	0.99
721_W	725_R	1.437	0.99
268_A	529_N	1.434	0.99
252_G	531_A	1.410	0.99
271_V	508_Y	1.406	0.99
428_L	431_K	1.391	0.99
426_R	497_S	1.381	0.99
257_D	506_K	1.376	0.98
536_E	546_T	1.374	0.98
532_H	550_T	1.357	0.98
281_Y	548_E	1.355	0.98
289_T	416_Q	1.345	0.98
449_Y	453_N	1.334	0.98
168_V	175_G	1.333	0.98
282_F	510_S	1.332	0.98
506_K	533_S	1.327	0.98
446_V	450_L	1.327	0.98
476_L	494_L	1.326	0.98
426_R	430_I	1.320	0.98
483_Y	532_H	1.318	0.98
435_D	445_A	1.317	0.98
496_R	501_P	1.312	0.98
432_L	498_A	1.310	0.98
272_F	331_V	1.306	0.98
273_T	523_I	1.297	0.98
683_T	686_D	1.295	0.98
282_F	511_G	1.287	0.98
542_Q	547_F	1.275	0.97
583_K	587_K	1.265	0.97
453_N	456_T	1.259	0.97
346_A	384_V	1.258	0.97
438_N	442_K	1.254	0.97
325_R	388_S	1.251	0.97
259_S	294_G	1.250	0.97
281_Y	532_H	1.249	0.97
459_T	550_T	1.247	0.97
425_V	472_V	1.238	0.97
447_E	491_M	1.238	0.97
645_V	648_V	1.237	0.97
290_Y	470_D	1.233	0.97
342_Y	346_A	1.229	0.97
281_Y	484_C	1.226	0.97
151_A	178_M	1.223	0.97
455_F	487_F	1.217	0.97
268_A	528_N	1.210	0.97
626_A	633_V	1.209	0.97
539_F	545_V	1.197	0.96
492_V	504_W	1.185	0.96
488_S	532_H	1.180	0.96
421_L	493_V	1.176	0.96
601_P	604_S	1.173	0.96
618_L	622_L	1.171	0.96
284_V	471_Y	1.169	0.96
425_V	473_D	1.167	0.96
218_G	229_P	1.163	0.96
441_D	445_A	1.161	0.96
274_W	537_V	1.153	0.95
500_I	505_V	1.152	0.95
284_V	450_L	1.152	0.95
221_A	224_S	1.151	0.95
442_K	445_A	1.151	0.95
709_R	720_L	1.149	0.95
425_V	494_L	1.147	0.95
721_W	728_W	1.140	0.95
540_P	543_G	1.136	0.95
274_W	329_V	1.130	0.95
548_E	553_F	1.129	0.95
206_P	211_V	1.126	0.95
485_D	533_S	1.124	0.95
644_P	648_V	1.124	0.95
546_T	549_P	1.122	0.95
418_P	421_L	1.120	0.95
396_L	539_F	1.120	0.95
436_H	441_D	1.118	0.95
630_V	634_L	1.117	0.95
495_L	549_P	1.117	0.95
133_H	136_V	1.116	0.95
660_F	706_S	1.113	0.94
257_D	260_L	1.111	0.94
634_L	639_R	1.111	0.94
439_M	500_I	1.109	0.94
108_Q	111_D	1.109	0.94
290_Y	471_Y	1.108	0.94
442_K	500_I	1.108	0.94
440_F	444_K	1.099	0.94
442_K	498_A	1.089	0.94
661_F	707_Y	1.082	0.94
341_M	528_N	1.079	0.94
450_L	551_K	1.074	0.93
421_L	426_R	1.074	0.93
638_F	642_W	1.071	0.93
281_Y	486_N	1.065	0.93
330_K	381_N	1.064	0.93
287_K	485_D	1.064	0.93
428_L	476_L	1.062	0.93
688_A	700_M	1.056	0.93
271_V	486_N	1.054	0.93
342_Y	366_I	1.046	0.92
437_D	441_D	1.045	0.92
122_F	508_Y	1.045	0.92
157_D	161_P	1.044	0.92
515_E	522_S	1.043	0.92
218_G	226_P	1.043	0.92
429_A	549_P	1.038	0.92
491_M	539_F	1.038	0.92
671_L	687_Y	1.037	0.92
702_K	723_D	1.037	0.92
286_T	446_V	1.034	0.92
270_P	332_D	1.034	0.92
453_N	480_K	1.034	0.92
636_Y	640_S	1.034	0.92
433_T	439_M	1.033	0.92
342_Y	386_Y	1.033	0.92
475_F	487_F	1.033	0.92
65_P	69_I	1.030	0.92
660_F	663_A	1.023	0.92
343_P	386_Y	1.019	0.91
666_A	669_K	1.018	0.91
290_Y	294_G	1.016	0.91
461_N	533_S	1.015	0.91
684_L	708_E	1.012	0.91
495_L	547_F	1.003	0.91
532_H	548_E	1.000	0.91
260_L	267_D	0.996	0.90
689_K	693_E	0.996	0.90
487_F	551_K	0.989	0.90
592_E	597_E	0.988	0.90
574_S	577_K	0.988	0.90
424_R	493_V	0.987	0.90
394_D	398_K	0.986	0.90
471_Y	485_D	0.985	0.90
343_P	346_A	0.985	0.90
289_T	296_I	0.984	0.90
342_Y	384_V	0.981	0.90
603_V	607_P	0.980	0.90
293_K	468_D	0.979	0.90
636_Y	639_R	0.978	0.90
475_F	532_H	0.974	0.89
721_W	724_S	0.971	0.89
688_A	692_D	0.970	0.89
293_K	471_Y	0.968	0.89
344_I	386_Y	0.967	0.89
75_I	79_F	0.966	0.89
206_P	218_G	0.965	0.89
175_G	182_L	0.965	0.89
690_R	694_K	0.962	0.89
335_Y	341_M	0.957	0.89
106_S	111_D	0.956	0.89
226_P	229_P	0.955	0.89
149_T	152_Y	0.952	0.88
208_S	212_L	0.951	0.88
208_S	211_V	0.949	0.88
584_E	588_Q	0.949	0.88
497_S	502_A	0.946	0.88
252_G	262_G	0.946	0.88
260_L	471_Y	0.946	0.88
443_V	539_F	0.944	0.88
447_E	535_V	0.943	0.88
624_V	629_L	0.943	0.88
107_G	110_N	0.940	0.88
210_L	227_A	0.935	0.87
585_E	589_P	0.932	0.87
344_I	546_T	0.929	0.87
664_Y	703_L	0.929	0.87
624_V	628_L	0.928	0.87
262_G	265_Q	0.928	0.87
620_A	623_A	0.927	0.87
88_S	91_S	0.925	0.87
583_K	586_K	0.925	0.87
45_V	680_D	0.924	0.87
271_V	528_N	0.923	0.87
593_E	596_K	0.922	0.87
703_L	728_W	0.921	0.87
461_N	465_P	0.920	0.87
229_P	232_V	0.919	0.87
648_V	651_L	0.918	0.86
407_E	411_S	0.917	0.86
471_Y	504_W	0.916	0.86
274_W	343_P	0.913	0.86
539_F	543_G	0.913	0.86
273_T	330_K	0.910	0.86
425_V	497_S	0.910	0.86
616_A	620_A	0.908	0.86
485_D	506_K	0.907	0.86
475_F	484_C	0.907	0.86
281_Y	546_T	0.903	0.86
535_V	539_F	0.903	0.86
682_E	686_D	0.902	0.86
357_L	360_N	0.897	0.85
672_K	678_K	0.896	0.85
466_K	469_E	0.896	0.85
725_R	728_W	0.896	0.85
582_Q	586_K	0.894	0.85
675_G	691_I	0.894	0.85
568_G	574_S	0.894	0.85
627_V	634_L	0.891	0.85
632_A	636_Y	0.886	0.84
217_F	221_A	0.882	0.84
329_V	384_V	0.882	0.84
428_L	490_A	0.877	0.84
450_L	453_N	0.874	0.84
169_I	176_F	0.872	0.84
443_V	549_P	0.868	0.83
707_Y	711_L	0.867	0.83
629_L	633_V	0.864	0.83
327_V	384_V	0.859	0.83
107_G	112_M	0.859	0.83
422_P	493_V	0.858	0.83
537_V	546_T	0.858	0.83
222_P	226_P	0.857	0.82
83_S	89_W	0.856	0.82
159_F	183_Y	0.855	0.82
571_S	576_K	0.854	0.82
596_K	600_E	0.852	0.82
285_E	506_K	0.850	0.82
692_D	696_D	0.849	0.82
257_D	485_D	0.849	0.82
624_V	633_V	0.847	0.82
267_D	527_T	0.847	0.82
450_L	487_F	0.846	0.82
509_T	530_N	0.846	0.82
43_F	130_Y	0.846	0.82
509_T	524_Y	0.845	0.82
268_A	527_T	0.844	0.81
432_L	495_L	0.843	0.81
622_L	634_L	0.842	0.81
261_G	486_N	0.842	0.81
165_T	169_I	0.842	0.81
264_F	459_T	0.839	0.81
469_E	474_Q	0.839	0.81
702_K	706_S	0.839	0.81
440_F	542_Q	0.838	0.81
286_T	505_V	0.837	0.81
157_D	160_T	0.836	0.81
598_K	601_P	0.836	0.81
706_S	709_R	0.835	0.81
281_Y	457_Y	0.832	0.81
211_V	225_E	0.832	0.81
432_L	449_Y	0.831	0.80
417_L	422_P	0.831	0.80
203_W	209_V	0.826	0.80
461_N	486_N	0.825	0.80
264_F	458_E	0.824	0.80
397_R	438_N	0.822	0.80
249_S	252_G	0.821	0.80
102_T	106_S	0.820	0.80
321_A	631_A	0.819	0.80
597_E	601_P	0.818	0.79
664_Y	707_Y	0.817	0.79
168_V	182_L	0.814	0.79
257_D	287_K	0.812	0.79
335_Y	508_Y	0.812	0.79
287_K	548_E	0.812	0.79
195_L	198_T	0.811	0.79
561_S	564_T	0.810	0.79
447_E	547_F	0.809	0.79
458_E	484_C	0.809	0.79
443_V	447_E	0.809	0.79
455_F	478_E	0.808	0.79
59_R	63_T	0.808	0.79
633_V	636_Y	0.805	0.78
421_L	425_V	0.805	0.78
203_W	218_G	0.802	0.78
290_Y	531_A	0.802	0.78
341_M	382_Y	0.801	0.78
721_W	729_E	0.800	0.78
226_P	712_Y	0.800	0.78
98_Y	102_T	0.799	0.78
212_L	420_S	0.798	0.78
706_S	727_L	0.797	0.78
209_V	212_L	0.797	0.78
380_G	384_V	0.797	0.78
150_V	154_T	0.796	0.78
290_Y	295_W	0.791	0.77
683_T	708_E	0.790	0.77
119_L	292_G	0.790	0.77
488_S	506_K	0.790	0.77
682_E	707_Y	0.789	0.77
617_G	620_A	0.787	0.77
597_E	600_E	0.787	0.77
211_V	216_G	0.785	0.77
329_V	341_M	0.784	0.76
484_C	531_A	0.783	0.76
649_R	652_K	0.782	0.76
491_M	550_T	0.780	0.76
599_R	603_V	0.780	0.76
446_V	547_F	0.780	0.76
664_Y	700_M	0.779	0.76
341_M	471_Y	0.779	0.76
287_K	491_M	0.777	0.76
631_A	635_L	0.777	0.76
66_F	214_A	0.777	0.76
505_V	535_V	0.777	0.76
91_S	98_Y	0.776	0.76
295_W	526_V	0.776	0.76
298_T	452_S	0.775	0.76
450_L	537_V	0.772	0.75
695_Y	703_L	0.771	0.75
721_W	727_L	0.771	0.75
61_F	65_P	0.771	0.75
626_A	630_V	0.770	0.75
475_F	480_K	0.770	0.75
182_L	186_R	0.770	0.75
660_F	724_S	0.769	0.75
287_K	549_P	0.768	0.75
615_G	619_Y	0.768	0.75
175_G	181_L	0.767	0.75
288_D	415_M	0.767	0.75
419_D	698_E	0.766	0.75
170_R	182_L	0.762	0.74
168_V	180_G	0.762	0.74
410_F	415_M	0.762	0.74
462_V	481_M	0.761	0.74
396_L	663_A	0.757	0.74
253_Y	261_G	0.757	0.74
429_A	443_V	0.757	0.74
689_K	701_S	0.756	0.74
723_D	726_E	0.753	0.74
676_L	691_I	0.753	0.74
53_L	65_P	0.751	0.73
472_V	493_V	0.751	0.73
508_Y	531_A	0.749	0.73
159_F	295_W	0.746	0.73
709_R	716_D	0.746	0.73
455_F	550_T	0.744	0.73
229_P	233_P	0.744	0.73
678_K	690_R	0.742	0.72
64_V	431_K	0.741	0.72
281_Y	508_Y	0.740	0.72
331_V	335_Y	0.734	0.72
252_G	257_D	0.734	0.72
586_K	589_P	0.733	0.72
294_G	504_W	0.733	0.72
710_A	715_E	0.731	0.71
589_P	593_E	0.731	0.71
203_W	221_A	0.730	0.71
267_D	484_C	0.729	0.71
274_W	510_S	0.728	0.71
284_V	531_A	0.728	0.71
476_L	545_V	0.727	0.71
455_F	549_P	0.726	0.71
669_K	673_R	0.726	0.71
141_R	144_F	0.726	0.71
272_F	687_Y	0.724	0.71
575_P	583_K	0.723	0.70
132_L	136_V	0.722	0.70
267_D	529_N	0.721	0.70
252_G	260_L	0.721	0.70
438_N	539_F	0.716	0.70
206_P	209_V	0.716	0.70
331_V	379_M	0.716	0.70
279_R	510_S	0.715	0.70
571_S	574_S	0.714	0.70
691_I	695_Y	0.713	0.69
625_L	639_R	0.713	0.69
121_F	129_V	0.712	0.69
216_G	225_E	0.711	0.69
171_I	176_F	0.711	0.69
203_W	210_L	0.710	0.69
607_P	610_S	0.709	0.69
431_K	434_Q	0.709	0.69
421_L	494_L	0.708	0.69
479_T	486_N	0.708	0.69
86_D	89_W	0.707	0.69
287_K	422_P	0.706	0.69
664_Y	708_E	0.706	0.69
493_V	502_A	0.704	0.68
621_A	625_L	0.704	0.68
670_Q	703_L	0.704	0.68
608_S	613_N	0.704	0.68
603_V	606_K	0.704	0.68
595_Q	600_E	0.702	0.68
340_L	376_I	0.701	0.68
218_G	225_E	0.699	0.68
458_E	548_E	0.698	0.68
641_L	648_V	0.698	0.68
475_F	490_A	0.698	0.68
470_D	474_Q	0.698	0.68
663_A	703_L	0.693	0.67
376_I	380_G	0.692	0.67
720_L	723_D	0.692	0.67
605_K	614_A	0.690	0.67
459_T	487_F	0.689	0.67
357_L	361_G	0.687	0.67
211_V	226_P	0.687	0.67
51_F	210_L	0.687	0.67
465_P	531_A	0.687	0.67
487_F	490_A	0.685	0.66
459_T	532_H	0.685	0.66
433_T	436_H	0.684	0.66
345_G	364_E	0.683	0.66
325_R	487_F	0.682	0.66
346_A	462_V	0.682	0.66
44_S	610_S	0.681	0.66
563_D	618_L	0.680	0.66
418_P	496_R	0.679	0.66
287_K	495_L	0.679	0.66
692_D	704_T	0.679	0.66
628_L	631_A	0.678	0.66
483_Y	531_A	0.678	0.66
315_W	320_V	0.678	0.66
343_P	510_S	0.677	0.65
270_P	275_Q	0.676	0.65
449_Y	524_Y	0.675	0.65
625_L	640_S	0.675	0.65
450_L	491_M	0.674	0.65
290_Y	422_P	0.673	0.65
667_L	703_L	0.673	0.65
508_Y	528_N	0.673	0.65
443_V	498_A	0.671	0.65
90_V	629_L	0.671	0.65
206_P	221_A	0.671	0.65
627_V	631_A	0.670	0.65
266_Q	459_T	0.670	0.65
324_R	385_T	0.669	0.65
80_Y	83_S	0.668	0.64
495_L	539_F	0.667	0.64
488_S	533_S	0.666	0.64
69_I	640_S	0.666	0.64
274_W	376_I	0.666	0.64
495_L	502_A	0.665	0.64
692_D	701_S	0.665	0.64
496_R	500_I	0.663	0.64
153_I	156_L	0.662	0.64
147_L	366_I	0.660	0.63
553_F	556_P	0.659	0.63
226_P	231_P	0.657	0.63
502_A	537_V	0.657	0.63
290_Y	446_V	0.657	0.63
106_S	109_W	0.656	0.63
687_Y	690_R	0.655	0.63
594_K	598_K	0.655	0.63
614_A	618_L	0.655	0.63
54_T	59_R	0.654	0.63
47_I	52_L	0.654	0.63
706_S	724_S	0.654	0.63
638_F	641_L	0.653	0.63
217_F	621_A	0.652	0.63
607_P	615_G	0.652	0.63
295_W	475_F	0.652	0.63
266_Q	529_N	0.651	0.62
459_T	462_V	0.651	0.62
455_F	504_W	0.650	0.62
155_I	159_F	0.650	0.62
133_H	142_I	0.649	0.62
679_R	690_R	0.649	0.62
287_K	341_M	0.649	0.62
513_Y	522_S	0.649	0.62
543_G	547_F	0.649	0.62
426_R	493_V	0.648	0.62
281_Y	511_G	0.648	0.62
46_F	712_Y	0.647	0.62
298_T	414_Y	0.647	0.62
553_F	557_A	0.647	0.62
614_A	621_A	0.647	0.62
80_Y	89_W	0.647	0.62
252_G	267_D	0.645	0.62
718_S	723_D	0.645	0.62
461_N	483_Y	0.644	0.62
204_F	210_L	0.644	0.62
129_V	218_G	0.643	0.61
328_R	452_S	0.641	0.61
398_K	434_Q	0.641	0.61
46_F	70_F	0.640	0.61
668_L	703_L	0.639	0.61
287_K	489_S	0.639	0.61
676_L	682_E	0.639	0.61
91_S	95_Q	0.638	0.61
347_E	387_N	0.637	0.61
136_V	142_I	0.637	0.61
177_F	540_P	0.637	0.61
703_L	724_S	0.637	0.61
253_Y	485_D	0.636	0.61
462_V	465_P	0.635	0.61
311_V	316_F	0.635	0.61
261_G	265_Q	0.634	0.60
379_M	604_S	0.634	0.60
339_H	483_Y	0.633	0.60
141_R	222_P	0.633	0.60
206_P	225_E	0.633	0.60
337_Y	341_M	0.632	0.60
204_F	218_G	0.632	0.60
62_V	197_K	0.631	0.60
472_V	476_L	0.631	0.60
626_A	639_R	0.631	0.60
471_Y	474_Q	0.630	0.60
572_S	575_P	0.629	0.60
54_T	133_H	0.629	0.60
488_S	553_F	0.629	0.60
100_N	107_G	0.628	0.60
645_V	649_R	0.627	0.60
324_R	347_E	0.626	0.59
591_K	594_K	0.626	0.59
222_P	228_W	0.625	0.59
414_Y	538_Y	0.625	0.59
561_S	565_K	0.625	0.59
562_S	566_D	0.624	0.59
684_L	688_A	0.624	0.59
472_V	485_D	0.623	0.59
266_Q	528_N	0.623	0.59
261_G	267_D	0.622	0.59
169_I	182_L	0.622	0.59
439_M	443_V	0.621	0.59
96_D	537_V	0.621	0.59
472_V	480_K	0.621	0.59
208_S	218_G	0.620	0.59
615_G	621_A	0.619	0.59
165_T	182_L	0.619	0.59
487_F	521_G	0.617	0.58
488_S	512_E	0.617	0.58
178_M	214_A	0.616	0.58
169_I	481_M	0.614	0.58
425_V	551_K	0.614	0.58
272_F	493_V	0.613	0.58
670_Q	674_K	0.613	0.58
178_M	182_L	0.612	0.58
273_T	525_E	0.611	0.58
132_L	149_T	0.611	0.58
167_A	171_I	0.611	0.58
65_P	608_S	0.611	0.58
418_P	493_V	0.611	0.58
46_F	180_G	0.611	0.58
292_G	416_Q	0.610	0.57
643_I	646_F	0.610	0.57
450_L	456_T	0.609	0.57
147_L	384_V	0.609	0.57
723_D	728_W	0.609	0.57
271_V	274_W	0.609	0.57
704_T	707_Y	0.609	0.57
159_F	280_T	0.609	0.57
285_E	339_H	0.608	0.57
470_D	493_V	0.608	0.57
666_A	673_R	0.608	0.57
179_L	182_L	0.607	0.57
484_C	509_T	0.607	0.57
374_G	377_R	0.605	0.57
456_T	597_E	0.604	0.57
100_N	104_I	0.603	0.57
421_L	497_S	0.602	0.56
216_G	689_K	0.601	0.56
149_T	153_I	0.601	0.56
432_L	491_M	0.601	0.56
284_V	331_V	0.600	0.56
582_Q	585_E	0.599	0.56
256_H	673_R	0.599	0.56
158_T	170_R	0.598	0.56
145_F	157_D	0.598	0.56
171_I	175_G	0.598	0.56
588_Q	595_Q	0.598	0.56
433_T	498_A	0.598	0.56
453_N	487_F	0.597	0.56
706_S	710_A	0.597	0.56
505_V	537_V	0.596	0.56
319_K	324_R	0.596	0.56
272_F	339_H	0.595	0.56
614_A	634_L	0.595	0.56
400_K	407_E	0.595	0.56
103_L	107_G	0.594	0.55
89_W	93_F	0.593	0.55
142_I	223_K	0.591	0.55
151_A	155_I	0.591	0.55
601_P	605_K	0.590	0.55
178_M	217_F	0.589	0.55
396_L	440_F	0.589	0.55
48_G	329_V	0.589	0.55
156_L	531_A	0.588	0.55
684_L	707_Y	0.588	0.55
264_F	486_N	0.587	0.55
611_H	615_G	0.587	0.55
266_Q	290_Y	0.587	0.55
263_P	460_E	0.586	0.54
630_V	714_N	0.586	0.54
44_S	723_D	0.585	0.54
569_S	572_S	0.585	0.54
630_V	636_Y	0.585	0.54
69_I	247_G	0.584	0.54
48_G	614_A	0.584	0.54
633_V	637_V	0.584	0.54
482_G	503_R	0.583	0.54
491_M	528_N	0.583	0.54
687_Y	704_T	0.583	0.54
588_Q	593_E	0.582	0.54
253_Y	257_D	0.581	0.54
348_T	385_T	0.581	0.54
211_V	489_S	0.580	0.54
233_P	487_F	0.580	0.54
340_L	349_I	0.579	0.54
535_V	547_F	0.578	0.53
464_I	474_Q	0.577	0.53
425_V	428_L	0.577	0.53
339_H	485_D	0.576	0.53
282_F	504_W	0.576	0.53
140_R	144_F	0.575	0.53
385_T	468_D	0.575	0.53
574_S	631_A	0.575	0.53
280_T	343_P	0.574	0.53
483_Y	708_E	0.574	0.53
567_S	628_L	0.574	0.53
168_V	415_M	0.573	0.53
510_S	548_E	0.572	0.53
665_G	717_S	0.572	0.53
270_P	529_N	0.572	0.53
69_I	512_E	0.571	0.53
613_N	621_A	0.571	0.53
418_P	538_Y	0.571	0.53
256_H	261_G	0.570	0.52
491_M	502_A	0.570	0.52
287_K	502_A	0.569	0.52
327_V	342_Y	0.568	0.52
718_S	721_W	0.568	0.52
500_I	677_P	0.567	0.52
324_R	387_N	0.566	0.52
503_R	507_G	0.566	0.52
46_F	71_T	0.565	0.52
490_A	499_G	0.565	0.52
82_G	575_P	0.565	0.52
546_T	552_G	0.564	0.52
278_E	399_V	0.563	0.52
491_M	494_L	0.563	0.52
626_A	631_A	0.563	0.52
360_N	530_N	0.563	0.52
79_F	119_L	0.563	0.52
451_G	548_E	0.562	0.51
116_F	329_V	0.562	0.51
431_K	435_D	0.562	0.51
472_V	477_F	0.561	0.51
170_R	505_V	0.560	0.51
103_L	631_A	0.560	0.51
443_V	455_F	0.560	0.51
65_P	147_L	0.559	0.51
128_L	132_L	0.559	0.51
485_D	492_V	0.558	0.51
252_G	261_G	0.557	0.51
253_Y	546_T	0.557	0.51
500_I	647_A	0.557	0.51
612_T	616_A	0.557	0.51
212_L	216_G	0.557	0.51
570_D	637_V	0.557	0.51
466_K	474_Q	0.557	0.51
115_S	118_T	0.556	0.51
629_L	640_S	0.556	0.51
542_Q	545_V	0.554	0.50
594_K	599_R	0.554	0.50
43_F	74_S	0.553	0.50
117_R	125_L	0.553	0.50
682_E	694_K	0.553	0.50
72_L	194_T	0.553	0.50
284_V	528_N	0.552	0.50
488_S	509_T	0.552	0.50
588_Q	605_K	0.552	0.50
205_L	209_V	0.552	0.50
76_H	86_D	0.551	0.50
486_N	509_T	0.551	0.50
260_L	487_F	0.550	0.50
285_E	504_W	0.550	0.50
527_T	687_Y	0.550	0.50
102_T	105_Q	0.549	0.50
570_D	575_P	0.548	0.50
581_K	585_E	0.547	0.50
443_V	535_V	0.547	0.50
339_H	489_S	0.546	0.49
267_D	457_Y	0.546	0.49
66_F	625_L	0.546	0.49
472_V	489_S	0.545	0.49
210_L	221_A	0.544	0.49
461_N	489_S	0.544	0.49
567_S	575_P	0.544	0.49
546_T	553_F	0.544	0.49
587_K	599_R	0.544	0.49
77_I	81_Q	0.543	0.49
295_W	496_R	0.543	0.49
627_V	649_R	0.543	0.49
482_G	507_G	0.543	0.49
217_F	222_P	0.543	0.49
68_V	71_T	0.542	0.49
344_I	548_E	0.542	0.49
304_Y	626_A	0.542	0.49
215_T	218_G	0.542	0.49
716_D	720_L	0.541	0.49
201_L	426_R	0.541	0.49
511_G	712_Y	0.541	0.49
285_E	365_Q	0.541	0.49
415_M	418_P	0.541	0.49
422_P	477_F	0.540	0.49
473_D	493_V	0.540	0.49
628_L	635_L	0.540	0.49
525_E	703_L	0.540	0.49
164_A	704_T	0.540	0.49
675_G	688_A	0.539	0.49
147_L	636_Y	0.538	0.48
264_F	457_Y	0.538	0.48
457_Y	534_W	0.538	0.48
251_I	261_G	0.537	0.48
500_I	670_Q	0.537	0.48
486_N	533_S	0.536	0.48
624_V	637_V	0.536	0.48
422_P	429_A	0.536	0.48
45_V	56_F	0.536	0.48
663_A	666_A	0.536	0.48
284_V	505_V	0.535	0.48
123_V	156_L	0.535	0.48
263_P	461_N	0.535	0.48
430_I	632_A	0.535	0.48
101_I	105_Q	0.535	0.48
261_G	485_D	0.534	0.48
687_Y	691_I	0.534	0.48
130_Y	149_T	0.533	0.48
292_G	422_P	0.532	0.48
455_F	459_T	0.532	0.48
123_V	597_E	0.531	0.48
249_S	416_Q	0.531	0.48
461_N	528_N	0.531	0.48
687_Y	695_Y	0.530	0.47
568_G	572_S	0.530	0.47
209_V	453_N	0.530	0.47
288_D	502_A	0.530	0.47
487_F	573_S	0.529	0.47
105_Q	472_V	0.529	0.47
350_Q	691_I	0.529	0.47
514_K	521_G	0.528	0.47
569_S	575_P	0.528	0.47
534_W	550_T	0.528	0.47
598_K	605_K	0.527	0.47
539_F	542_Q	0.526	0.47
201_L	227_A	0.526	0.47
217_F	623_A	0.525	0.47
42_F	129_V	0.525	0.47
287_K	339_H	0.524	0.47
54_T	62_V	0.524	0.47
44_S	64_V	0.524	0.47
282_F	488_S	0.524	0.47
200_V	209_V	0.523	0.47
155_I	230_D	0.523	0.47
491_M	500_I	0.523	0.47
68_V	632_A	0.523	0.47
121_F	159_F	0.522	0.46
559_F	562_S	0.522	0.46
203_W	206_P	0.522	0.46
595_Q	598_K	0.522	0.46
495_L	546_T	0.522	0.46
397_R	439_M	0.521	0.46
626_A	636_Y	0.521	0.46
144_F	148_M	0.521	0.46
206_P	217_F	0.521	0.46
339_H	344_I	0.521	0.46
601_P	606_K	0.521	0.46
259_S	688_A	0.521	0.46
308_N	311_V	0.520	0.46
633_V	648_V	0.520	0.46
59_R	700_M	0.520	0.46
269_T	528_N	0.520	0.46
131_L	163_D	0.520	0.46
492_V	497_S	0.520	0.46
684_L	704_T	0.520	0.46
335_Y	546_T	0.519	0.46
447_E	495_L	0.519	0.46
253_Y	483_Y	0.519	0.46
208_S	226_P	0.518	0.46
450_L	472_V	0.518	0.46
164_A	167_A	0.518	0.46
136_V	223_K	0.517	0.46
253_Y	256_H	0.517	0.46
272_F	284_V	0.517	0.46
471_Y	489_S	0.517	0.46
273_T	548_E	0.516	0.46
287_K	331_V	0.516	0.46
328_R	382_Y	0.515	0.46
149_T	154_T	0.514	0.45
503_R	536_E	0.513	0.45
684_L	711_L	0.513	0.45
321_A	591_K	0.513	0.45
458_E	483_Y	0.512	0.45
569_S	573_S	0.512	0.45
76_H	80_Y	0.512	0.45
102_T	112_M	0.511	0.45
475_F	482_G	0.511	0.45
482_G	544_W	0.511	0.45
569_S	594_K	0.510	0.45
724_S	729_E	0.510	0.45
147_L	179_L	0.509	0.45
260_L	422_P	0.509	0.45
639_R	651_L	0.509	0.45
42_F	47_I	0.508	0.45
420_S	426_R	0.508	0.45
286_T	495_L	0.508	0.45
607_P	626_A	0.508	0.45
87_L	633_V	0.508	0.45
459_T	485_D	0.507	0.45
287_K	294_G	0.507	0.45
540_P	553_F	0.507	0.45
172_V	204_F	0.507	0.45
485_D	510_S	0.507	0.45
610_S	619_Y	0.507	0.45
496_R	531_A	0.507	0.45
224_S	227_A	0.506	0.44
297_E	465_P	0.506	0.44
134_Y	138_Y	0.506	0.44
590_Q	593_E	0.506	0.44
210_L	229_P	0.505	0.44
253_Y	285_E	0.504	0.44
507_G	534_W	0.504	0.44
590_Q	608_S	0.504	0.44
610_S	618_L	0.504	0.44
252_G	484_C	0.503	0.44
447_E	500_I	0.502	0.44
526_V	699_D	0.502	0.44
722_N	726_E	0.502	0.44
253_Y	271_V	0.502	0.44
121_F	485_D	0.501	0.44
537_V	548_E	0.500	0.44
375_E	533_S	0.500	0.44
288_D	492_V	0.500	0.44
566_D	571_S	0.500	0.44
711_L	714_N	0.500	0.44

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4ktyA	1	0.5658	100	0.789	Contact Map
4xz7A	2	0.4776	100	0.801	Contact Map
2q3zA	2	0.5237	100	0.804	Contact Map
1g0dA	1	0.5522	99.9	0.814	Contact Map
1l9mA	2	0.559	99.9	0.819	Contact Map
3isrA	3	0.3826	99.9	0.82	Contact Map
2f4mA	2	0.3392	99.9	0.833	Contact Map
1x3zA	1	0.3691	99.9	0.835	Contact Map
3kd4A	3	0.5156	99.9	0.841	Contact Map
4fgqA	1	0.2442	99.5	0.886	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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