FMT - BACSU - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

FMT - Methionyl-tRNA formyltransferase

UniProt:	P94463	Sequences: MTRIVFMGTPDFSVPVLRTLIEDGYEVVGVVTQPDRPKGRKKVLTPPPVKEEALRHGIPVLQPEKVRLTEEIEKVLALKPDLIVTAAFGQILPKELLDSPKYGCINVHASLLPELRGGAPIHYSILQGKKKTGITIMYMVEKLDAGDMISKVEVDIEETDNVGTLHDKLSVAGAKLLSETVPNVIAGSISPEKQDEEKATYAPNIKREQELLDWSRTGEELYNQIRGLNPWPVAYTTLNGQNLKIWASKKIAAPTTAEPGTVVAVEKEGIIVATGNETALLLTELQPAGKKRMKGEDFVRGAHVEAGDVLGVNNEKN	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	317 (300)
Sequences:	5538 (4018)
Seq/√Len:	232.0

ECOLI - FMT ARNA PUR3
BACSU - FMT PUR3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
131_K	153_E	4.105	1.00
94_K	141_E	3.641	1.00
94_K	98_D	3.420	1.00
195_D	198_K	3.350	1.00
294_K	297_D	3.086	1.00
216_R	220_E	2.899	1.00
152_V	179_E	2.741	1.00
21_I	56_H	2.645	1.00
140_V	145_A	2.635	1.00
135_T	148_M	2.573	1.00
160_D	168_K	2.539	1.00
160_D	164_T	2.480	1.00
142_K	145_A	2.404	1.00
212_L	221_L	2.397	1.00
222_Y	248_S	2.295	1.00
225_I	248_S	2.237	1.00
3_R	26_E	2.219	1.00
249_K	281_L	2.212	1.00
18_R	52_E	2.185	1.00
136_I	180_T	2.182	1.00
249_K	283_T	2.169	1.00
183_N	188_S	2.135	1.00
114_E	129_K	2.118	1.00
247_A	284_E	2.114	1.00
115_L	129_K	2.103	1.00
284_E	292_R	2.092	1.00
115_L	127_Q	2.034	1.00
18_R	22_E	2.025	1.00
216_R	224_Q	2.000	1.00
29_G	78_L	1.995	1.00
73_E	77_A	1.982	1.00
122_H	162_V	1.947	1.00
163_G	230_P	1.942	1.00
52_E	56_H	1.942	1.00
271_I	279_A	1.927	1.00
82_L	181_V	1.897	1.00
247_A	283_T	1.893	1.00
126_L	227_G	1.874	1.00
271_I	281_L	1.858	1.00
217_T	220_E	1.836	1.00
258_E	261_T	1.799	1.00
241_Q	288_A	1.756	1.00
154_V	172_A	1.732	1.00
131_K	155_D	1.723	1.00
138_Y	191_P	1.722	1.00
147_D	193_K	1.714	1.00
196_E	199_A	1.710	1.00
59_P	74_K	1.702	1.00
296_E	300_R	1.692	1.00
16_V	107_V	1.688	1.00
282_L	285_L	1.684	1.00
297_D	300_R	1.682	1.00
154_V	168_K	1.665	1.00
246_W	292_R	1.652	1.00
123_Y	209_Q	1.617	1.00
5_V	80_P	1.578	1.00
214_W	236_T	1.576	1.00
269_G	281_L	1.548	1.00
152_V	175_K	1.540	1.00
21_I	52_E	1.535	1.00
212_L	245_I	1.523	1.00
157_E	160_D	1.523	1.00
35_D	50_K	1.523	1.00
128_G	223_N	1.516	1.00
52_E	55_R	1.512	1.00
80_P	83_I	1.500	1.00
248_S	280_L	1.473	1.00
221_L	280_L	1.467	1.00
80_P	99_S	1.464	1.00
50_K	62_Q	1.463	1.00
151_K	192_E	1.457	1.00
213_D	216_R	1.456	1.00
74_K	77_A	1.450	1.00
51_E	54_L	1.444	1.00
46_P	54_L	1.429	1.00
111_L	133_G	1.429	1.00
3_R	28_V	1.420	1.00
219_E	223_N	1.412	1.00
135_T	151_K	1.391	1.00
50_K	54_L	1.383	1.00
14_V	52_E	1.372	1.00
19_T	175_K	1.370	1.00
263_V	279_A	1.369	1.00
19_T	178_S	1.368	1.00
161_N	229_N	1.346	1.00
270_I	282_L	1.344	1.00
147_D	191_P	1.341	1.00
284_E	294_K	1.337	1.00
51_E	55_R	1.331	1.00
152_V	172_A	1.328	1.00
222_Y	250_K	1.324	1.00
270_I	295_G	1.305	1.00
126_L	228_L	1.302	1.00
149_I	191_P	1.293	1.00
287_P	293_M	1.293	1.00
148_M	151_K	1.293	1.00
257_A	261_T	1.286	1.00
150_S	180_T	1.286	1.00
126_L	224_Q	1.285	1.00
67_R	93_P	1.281	1.00
9_T	47_P	1.279	1.00
4_I	82_L	1.274	1.00
236_T	245_I	1.269	1.00
138_Y	149_I	1.266	1.00
157_E	168_K	1.265	1.00
16_V	177_L	1.264	1.00
218_G	250_K	1.257	1.00
211_L	237_T	1.257	1.00
5_V	29_G	1.250	1.00
25_Y	182_P	1.250	1.00
107_V	177_L	1.247	1.00
18_R	55_R	1.241	1.00
140_V	147_D	1.227	1.00
211_L	235_Y	1.208	1.00
179_E	183_N	1.206	1.00
222_Y	226_R	1.199	1.00
83_I	104_C	1.196	1.00
91_I	143_L	1.195	1.00
150_S	183_N	1.191	1.00
69_T	73_E	1.190	1.00
217_T	276_N	1.187	1.00
272_V	282_L	1.185	1.00
111_L	151_K	1.185	1.00
123_Y	126_L	1.183	1.00
21_I	27_V	1.168	1.00
38_K	41_K	1.167	1.00
132_T	156_I	1.165	1.00
23_D	178_S	1.164	1.00
183_N	189_I	1.149	1.00
123_Y	127_Q	1.149	1.00
61_L	78_L	1.145	1.00
251_I	271_I	1.130	1.00
16_V	86_A	1.125	1.00
195_D	199_A	1.124	1.00
150_S	176_L	1.116	1.00
218_G	276_N	1.096	1.00
245_I	282_L	1.091	1.00
125_I	165_L	1.089	1.00
118_G	204_N	1.089	1.00
243_L	285_L	1.082	1.00
218_G	274_T	1.081	1.00
251_I	281_L	1.079	1.00
29_G	61_L	1.076	1.00
156_I	160_D	1.072	1.00
266_E	269_G	1.068	1.00
114_E	200_T	1.066	1.00
159_T	222_Y	1.065	1.00
157_E	164_T	1.065	1.00
97_L	139_M	1.064	1.00
286_Q	292_R	1.049	1.00
73_E	76_L	1.049	1.00
38_K	45_T	1.044	1.00
236_T	243_L	1.035	1.00
6_F	16_V	1.035	1.00
119_A	123_Y	1.031	1.00
81_D	101_K	1.028	1.00
32_T	47_P	1.027	1.00
46_P	51_E	1.024	1.00
31_V	71_E	1.017	1.00
150_S	179_E	1.012	1.00
28_V	78_L	1.003	1.00
36_R	64_E	1.003	1.00
136_I	150_S	1.001	1.00
30_V	58_I	0.996	1.00
76_L	95_E	0.994	1.00
237_T	240_G	0.994	1.00
152_V	176_L	0.972	1.00
298_F	302_A	0.964	1.00
105_I	149_I	0.961	1.00
164_T	168_K	0.961	1.00
100_P	104_C	0.945	1.00
7_M	31_V	0.944	1.00
25_Y	185_I	0.930	1.00
107_V	136_I	0.929	1.00
119_A	202_A	0.926	1.00
214_W	272_V	0.921	1.00
104_C	139_M	0.921	1.00
161_N	164_T	0.920	1.00
218_G	278_T	0.918	1.00
66_V	71_E	0.911	1.00
287_P	298_F	0.910	1.00
121_I	166_H	0.909	1.00
7_M	83_I	0.902	0.99
237_T	242_N	0.900	0.99
257_A	273_A	0.900	0.99
208_E	211_L	0.899	0.99
20_L	181_V	0.898	0.99
72_I	95_E	0.897	0.99
229_N	246_W	0.894	0.99
182_P	185_I	0.890	0.99
41_K	45_T	0.887	0.99
76_L	99_S	0.886	0.99
290_K	293_M	0.886	0.99
2_T	185_I	0.885	0.99
159_T	249_K	0.880	0.99
225_I	234_A	0.874	0.99
10_P	87_A	0.872	0.99
223_N	226_R	0.871	0.99
149_I	184_V	0.871	0.99
159_T	247_A	0.868	0.99
221_L	274_T	0.868	0.99
33_Q	36_R	0.866	0.99
114_E	198_K	0.866	0.99
15_P	170_S	0.864	0.99
149_I	189_I	0.863	0.99
107_V	134_I	0.862	0.99
61_L	74_K	0.859	0.99
206_K	209_Q	0.859	0.99
123_Y	202_A	0.857	0.99
130_K	155_D	0.854	0.99
109_A	121_I	0.853	0.99
158_E	219_E	0.853	0.99
222_Y	280_L	0.851	0.99
105_I	136_I	0.840	0.99
160_D	165_L	0.837	0.99
184_V	189_I	0.836	0.99
251_I	279_A	0.836	0.99
224_Q	228_L	0.835	0.99
220_E	223_N	0.835	0.99
261_T	273_A	0.832	0.99
265_V	270_I	0.832	0.99
35_D	62_Q	0.832	0.99
285_L	298_F	0.824	0.99
171_V	175_K	0.817	0.99
245_I	248_S	0.809	0.99
243_L	287_P	0.808	0.99
82_L	103_G	0.808	0.99
23_D	182_P	0.801	0.99
3_R	79_K	0.799	0.99
295_G	299_V	0.797	0.99
19_T	23_D	0.791	0.99
66_V	72_I	0.790	0.99
71_E	74_K	0.789	0.99
266_E	271_I	0.787	0.99
72_I	96_L	0.786	0.99
29_G	74_K	0.784	0.99
18_R	56_H	0.783	0.99
259_P	273_A	0.783	0.99
12_F	109_A	0.782	0.99
215_S	275_G	0.782	0.99
219_E	222_Y	0.782	0.99
176_L	180_T	0.778	0.98
183_N	186_A	0.777	0.98
47_P	62_Q	0.776	0.98
242_N	288_A	0.776	0.98
69_T	72_I	0.772	0.98
210_E	235_Y	0.771	0.98
83_I	100_P	0.771	0.98
158_E	222_Y	0.765	0.98
235_Y	242_N	0.764	0.98
65_K	68_L	0.763	0.98
31_V	61_L	0.759	0.98
15_P	18_R	0.756	0.98
19_T	22_E	0.753	0.98
22_E	52_E	0.753	0.98
273_A	279_A	0.749	0.98
22_E	56_H	0.743	0.98
210_E	231_W	0.740	0.98
80_P	100_P	0.738	0.98
38_K	43_V	0.737	0.98
123_Y	203_P	0.736	0.98
85_T	139_M	0.727	0.98
4_I	25_Y	0.726	0.98
10_P	13_S	0.726	0.98
172_A	176_L	0.724	0.98
220_E	224_Q	0.723	0.98
61_L	71_E	0.723	0.98
246_W	286_Q	0.720	0.98
66_V	90_Q	0.717	0.97
241_Q	287_P	0.714	0.97
244_K	286_Q	0.710	0.97
109_A	169_L	0.710	0.97
68_L	71_E	0.710	0.97
287_P	290_K	0.709	0.97
86_A	136_I	0.709	0.97
154_V	160_D	0.708	0.97
98_D	141_E	0.700	0.97
124_S	156_I	0.700	0.97
122_H	227_G	0.696	0.97
105_I	177_L	0.695	0.97
219_E	276_N	0.692	0.97
70_E	73_E	0.692	0.97
125_I	156_I	0.692	0.97
125_I	227_G	0.691	0.97
233_V	246_W	0.687	0.97
210_E	233_V	0.685	0.97
19_T	174_A	0.671	0.96
182_P	186_A	0.667	0.96
69_T	95_E	0.667	0.96
106_N	137_M	0.666	0.96
5_V	83_I	0.665	0.96
167_D	171_V	0.665	0.96
21_I	58_I	0.664	0.96
127_Q	203_P	0.664	0.96
123_Y	204_N	0.661	0.96
63_P	88_F	0.661	0.96
135_T	149_I	0.659	0.96
13_S	16_V	0.658	0.96
136_I	176_L	0.655	0.96
97_L	104_C	0.655	0.96
121_I	162_V	0.653	0.96
75_V	96_L	0.653	0.96
122_H	231_W	0.652	0.96
238_L	243_L	0.651	0.96
20_L	27_V	0.650	0.95
163_G	167_D	0.650	0.95
255_T	273_A	0.644	0.95
259_P	274_T	0.642	0.95
82_L	105_I	0.641	0.95
252_A	278_T	0.641	0.95
65_K	90_Q	0.641	0.95
255_T	279_A	0.641	0.95
138_Y	147_D	0.640	0.95
76_L	79_K	0.640	0.95
16_V	19_T	0.640	0.95
130_K	158_E	0.640	0.95
33_Q	90_Q	0.639	0.95
161_N	247_A	0.636	0.95
148_M	192_E	0.634	0.95
6_F	17_L	0.634	0.95
72_I	76_L	0.633	0.95
16_V	174_A	0.631	0.95
109_A	122_H	0.631	0.95
24_G	182_P	0.625	0.94
123_Y	227_G	0.624	0.94
107_V	173_G	0.623	0.94
268_E	296_E	0.623	0.94
45_T	51_E	0.621	0.94
79_K	101_K	0.620	0.94
12_F	173_G	0.620	0.94
142_K	196_E	0.619	0.94
293_M	297_D	0.618	0.94
111_L	153_E	0.617	0.94
263_V	273_A	0.617	0.94
134_I	172_A	0.616	0.94
109_A	124_S	0.615	0.94
175_K	179_E	0.615	0.94
90_Q	93_P	0.612	0.94
210_E	228_L	0.610	0.94
105_I	191_P	0.610	0.94
5_V	31_V	0.609	0.94
229_N	292_R	0.606	0.93
74_K	78_L	0.605	0.93
225_I	245_I	0.604	0.93
205_I	231_W	0.604	0.93
257_A	263_V	0.603	0.93
21_I	24_G	0.603	0.93
162_V	166_H	0.603	0.93
270_I	281_L	0.602	0.93
287_P	302_A	0.601	0.93
12_F	121_I	0.600	0.93
132_T	165_L	0.599	0.93
172_A	175_K	0.598	0.93
75_V	83_I	0.598	0.93
65_K	72_I	0.595	0.93
281_L	295_G	0.589	0.93
5_V	75_V	0.587	0.92
95_E	98_D	0.584	0.92
233_V	244_K	0.584	0.92
40_R	44_L	0.583	0.92
64_E	68_L	0.583	0.92
162_V	205_I	0.582	0.92
37_P	42_K	0.581	0.92
124_S	129_K	0.580	0.92
164_T	222_Y	0.580	0.92
103_G	138_Y	0.577	0.92
86_A	173_G	0.576	0.92
168_K	172_A	0.575	0.92
114_E	199_A	0.574	0.92
219_E	250_K	0.573	0.91
130_K	219_E	0.572	0.91
262_V	272_V	0.572	0.91
234_A	248_S	0.571	0.91
274_T	279_A	0.570	0.91
217_T	275_G	0.569	0.91
89_G	137_M	0.568	0.91
110_S	120_P	0.567	0.91
164_T	247_A	0.567	0.91
205_I	209_Q	0.566	0.91
207_R	210_E	0.566	0.91
222_Y	225_I	0.563	0.91
41_K	44_L	0.561	0.91
66_V	96_L	0.559	0.90
229_N	233_V	0.559	0.90
17_L	30_V	0.558	0.90
31_V	75_V	0.557	0.90
2_T	81_D	0.557	0.90
174_A	178_S	0.557	0.90
109_A	151_K	0.556	0.90
163_G	229_N	0.555	0.90
162_V	227_G	0.555	0.90
270_I	285_L	0.549	0.90
140_V	143_L	0.549	0.90
214_W	221_L	0.548	0.90
285_L	295_G	0.547	0.89
5_V	28_V	0.547	0.89
115_L	202_A	0.545	0.89
136_I	173_G	0.542	0.89
269_G	295_G	0.542	0.89
88_F	91_I	0.540	0.89
92_L	104_C	0.540	0.89
37_P	44_L	0.539	0.89
109_A	118_G	0.539	0.89
274_T	278_T	0.535	0.88
32_T	49_V	0.533	0.88
210_E	229_N	0.533	0.88
102_Y	185_I	0.532	0.88
83_I	99_S	0.532	0.88
53_A	60_V	0.530	0.88
65_K	71_E	0.529	0.88
251_I	278_T	0.527	0.88
30_V	49_V	0.526	0.88
135_T	140_V	0.526	0.88
12_F	86_A	0.525	0.88
88_F	106_N	0.524	0.87
125_I	162_V	0.523	0.87
158_E	250_K	0.522	0.87
2_T	25_Y	0.519	0.87
46_P	50_K	0.518	0.87
32_T	62_Q	0.518	0.87
121_I	169_L	0.518	0.87
122_H	205_I	0.518	0.87
248_S	283_T	0.517	0.87
105_I	180_T	0.517	0.87
31_V	66_V	0.517	0.87
143_L	199_A	0.516	0.87
265_V	299_V	0.514	0.86
212_L	224_Q	0.512	0.86
12_F	107_V	0.512	0.86
109_A	166_H	0.511	0.86
291_K	297_D	0.511	0.86
70_E	74_K	0.510	0.86
82_L	184_V	0.510	0.86
15_P	52_E	0.509	0.86
229_N	247_A	0.506	0.86
15_P	171_V	0.506	0.86
276_N	279_A	0.505	0.85
30_V	53_A	0.504	0.85
82_L	138_Y	0.503	0.85
16_V	170_S	0.503	0.85
136_I	177_L	0.502	0.85
179_E	182_P	0.502	0.85
126_L	209_Q	0.502	0.85
122_H	166_H	0.501	0.85
124_S	132_T	0.501	0.85
72_I	93_P	0.501	0.85
250_K	280_L	0.501	0.85
27_V	58_I	0.501	0.85
114_E	127_Q	0.500	0.85
2_T	26_E	0.500	0.85

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4iqfA	1	0.9811	100	0.089	Contact Map
3tqqA	1	0.9495	100	0.091	Contact Map
3q0iA	1	0.9464	100	0.097	Contact Map
1fmtA	1	0.959	100	0.098	Contact Map
2blnA	1	0.9369	100	0.133	Contact Map
4wkgA	5	0.9432	100	0.151	Contact Map
2bw0A	1	0.918	100	0.166	Contact Map
4lxqA	2	0.8454	100	0.277	Contact Map
4xczA	2	0.9211	100	0.302	Contact Map
1zghA	1	0.7003	100	0.358	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.01 seconds.