YCLN - BACSU - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

YCLN - Uncharacterized ABC transporter permease protein YclN

UniProt:	P94418	Sequences: MKLRYLFILLIILAVTSVFIGVEDLSPLDLFDLSKQEASTLFASRLPRLISIVIAGLSMSICGLIMQQISRNKFVSPTTAGTMDWARLGILISLLLFTSASPLIKMLVAFVFALAGNFLFMKILERIKFNDTIFIPLVGLMLGNIVSSIATFIAYKYDLIQNVSSWLQGDFSLVVKGRYELLYLSIPLVIIAYVYADKFTLAGMGESFSVNLGLKYKRVVNIGLIIVSLITSLVILTVGMLPFLGLIIPNIVSIYRGDNLKSSLPHTVLLGAVFVLFCDILGRIIIFPYEISIGLMVGIIGSGIFLFMLLRRKAYA	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	316 (308)
Sequences:	13692 (9708)
Seq/√Len:	553.2

ECOLI - FEPG BTUC FEPD FECC FECD FHUB
BACSU - YCLN FHUB FHUG FEUC YVRB FEUB YFME YFMD YFHA YFIZ YCLO
HALSA - Q9HMG7 Q9HMG0 BTUCA
SULSO - Q97ZU1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
200_T	259_N	4.277	1.00
57_L	268_V	3.717	1.00
93_S	108_V	3.582	1.00
13_L	277_F	3.463	1.00
65_I	192_A	3.455	1.00
14_A	49_L	3.259	1.00
215_K	218_R	3.208	1.00
65_I	223_G	3.025	1.00
53_V	272_A	2.949	1.00
58_S	186_I	2.905	1.00
52_I	171_F	2.834	1.00
252_V	270_L	2.790	1.00
29_D	37_E	2.700	1.00
51_S	174_V	2.588	1.00
58_S	230_I	2.523	1.00
61_I	268_V	2.511	1.00
58_S	234_V	2.425	1.00
88_L	149_I	2.420	1.00
14_A	53_V	2.394	1.00
29_D	32_D	2.383	1.00
206_E	220_V	2.370	1.00
10_L	273_V	2.314	1.00
55_A	234_V	2.247	1.00
64_L	267_T	2.231	1.00
9_L	273_V	2.222	1.00
61_I	189_V	2.222	1.00
256_R	266_H	2.190	1.00
53_V	276_L	2.097	1.00
19_F	27_P	2.091	1.00
198_K	219_V	2.060	1.00
55_A	238_V	2.047	1.00
185_S	233_L	2.025	1.00
34_S	37_E	2.023	1.00
88_L	146_V	1.996	1.00
26_S	29_D	1.978	1.00
10_L	53_V	1.961	1.00
54_I	183_Y	1.943	1.00
92_I	96_L	1.930	1.00
195_Y	198_K	1.895	1.00
48_R	279_D	1.888	1.00
66_M	227_V	1.854	1.00
68_Q	260_L	1.848	1.00
201_L	214_L	1.827	1.00
200_T	260_L	1.825	1.00
17_S	49_L	1.806	1.00
28_L	32_D	1.803	1.00
35_K	38_A	1.800	1.00
191_I	226_I	1.796	1.00
91_L	150_A	1.777	1.00
38_A	42_F	1.765	1.00
13_L	273_V	1.744	1.00
174_V	178_R	1.662	1.00
195_Y	222_I	1.657	1.00
64_L	263_S	1.587	1.00
50_I	179_Y	1.575	1.00
244_L	275_V	1.554	1.00
175_V	178_R	1.550	1.00
180_E	184_L	1.548	1.00
218_R	222_I	1.541	1.00
195_Y	219_V	1.538	1.00
281_L	285_I	1.526	1.00
113_A	232_S	1.514	1.00
90_I	109_A	1.511	1.00
33_L	42_F	1.511	1.00
6_L	269_L	1.510	1.00
117_N	228_S	1.493	1.00
10_L	269_L	1.474	1.00
16_T	20_I	1.469	1.00
89_G	108_V	1.469	1.00
16_T	19_F	1.467	1.00
282_G	293_I	1.449	1.00
17_S	280_I	1.418	1.00
262_S	265_P	1.417	1.00
171_F	275_V	1.398	1.00
252_V	266_H	1.390	1.00
281_L	296_M	1.375	1.00
6_L	266_H	1.375	1.00
13_L	276_L	1.358	1.00
191_I	195_Y	1.340	1.00
62_C	230_I	1.323	1.00
195_Y	223_G	1.307	1.00
6_L	270_L	1.303	1.00
51_S	237_T	1.277	1.00
180_E	183_Y	1.271	1.00
210_V	217_K	1.266	1.00
184_L	188_L	1.264	1.00
116_G	146_V	1.258	1.00
33_L	38_A	1.251	1.00
145_I	302_S	1.247	1.00
248_I	270_L	1.246	1.00
87_R	150_A	1.246	1.00
252_V	263_S	1.243	1.00
54_I	179_Y	1.234	1.00
36_Q	39_S	1.233	1.00
39_S	43_A	1.228	1.00
208_F	211_N	1.225	1.00
89_G	112_F	1.224	1.00
248_I	274_F	1.220	1.00
24_D	27_P	1.220	1.00
83_M	231_T	1.220	1.00
10_L	272_A	1.202	1.00
201_L	212_L	1.196	1.00
33_L	41_L	1.187	1.00
218_R	221_N	1.185	1.00
238_V	241_L	1.179	1.00
69_I	223_G	1.178	1.00
60_S	248_I	1.170	1.00
85_W	116_G	1.160	1.00
260_L	263_S	1.158	1.00
101_S	104_I	1.157	1.00
107_L	111_V	1.153	1.00
219_V	222_I	1.150	1.00
6_L	273_V	1.145	1.00
91_L	163_V	1.143	1.00
52_I	276_L	1.135	1.00
87_R	167_L	1.134	1.00
190_I	194_V	1.132	1.00
57_L	272_A	1.131	1.00
182_L	237_T	1.127	1.00
64_L	264_L	1.124	1.00
52_I	275_V	1.110	1.00
95_L	153_I	1.108	1.00
217_K	220_V	1.107	1.00
23_E	40_T	1.107	1.00
192_A	226_I	1.106	1.00
143_G	147_S	1.102	1.00
191_I	222_I	1.097	1.00
88_L	92_I	1.096	1.00
51_S	179_Y	1.094	1.00
57_L	60_S	1.083	1.00
118_F	122_K	1.081	1.00
283_R	290_E	1.080	1.00
85_W	112_F	1.073	1.00
265_P	268_V	1.073	1.00
205_G	209_S	1.067	1.00
217_K	221_N	1.059	1.00
110_F	229_L	1.050	1.00
184_L	187_P	1.049	1.00
15_V	19_F	1.046	1.00
84_D	146_V	1.046	1.00
54_I	182_L	1.039	1.00
120_F	142_L	1.038	1.00
20_I	284_I	1.036	1.00
64_L	260_L	1.035	1.00
262_S	266_H	1.034	1.00
182_L	186_I	1.033	1.00
108_V	112_F	1.025	1.00
152_F	156_K	1.022	1.00
256_R	262_S	1.020	1.00
50_I	176_K	1.017	1.00
42_F	46_L	1.017	1.00
8_I	12_I	1.011	1.00
199_F	223_G	1.006	1.00
219_V	223_G	0.998	1.00
282_G	296_M	0.997	1.00
30_L	41_L	0.997	1.00
92_I	153_I	0.996	1.00
281_L	284_I	0.994	1.00
125_E	217_K	0.993	1.00
30_L	33_L	0.990	1.00
273_V	277_F	0.983	1.00
279_D	283_R	0.971	1.00
115_A	119_L	0.970	1.00
18_V	49_L	0.966	1.00
7_F	11_I	0.966	1.00
303_G	307_F	0.961	1.00
248_I	252_V	0.961	1.00
83_M	240_M	0.960	1.00
14_A	276_L	0.959	1.00
241_L	275_V	0.955	1.00
49_L	280_I	0.950	1.00
33_L	37_E	0.945	1.00
19_F	30_L	0.944	1.00
95_L	157_Y	0.942	1.00
13_L	280_I	0.932	1.00
255_Y	270_L	0.931	1.00
181_L	184_L	0.926	1.00
263_S	267_T	0.926	1.00
88_L	150_A	0.923	1.00
286_I	289_Y	0.916	1.00
234_V	238_V	0.912	1.00
38_A	43_A	0.905	1.00
298_G	303_G	0.903	1.00
207_S	210_V	0.903	1.00
82_T	113_A	0.903	1.00
214_L	219_V	0.895	1.00
304_I	307_F	0.894	1.00
176_K	179_Y	0.888	1.00
221_N	225_I	0.886	1.00
206_E	210_V	0.883	1.00
259_N	262_S	0.877	1.00
15_V	27_P	0.875	1.00
277_F	281_L	0.871	1.00
19_F	24_D	0.864	1.00
88_L	153_I	0.861	1.00
200_T	261_K	0.860	1.00
191_I	194_V	0.858	1.00
94_L	105_K	0.855	1.00
62_C	227_V	0.855	1.00
125_E	128_K	0.847	1.00
7_F	269_L	0.846	1.00
57_L	189_V	0.845	1.00
25_L	41_L	0.845	1.00
86_A	113_A	0.844	1.00
178_R	237_T	0.843	1.00
177_G	180_E	0.842	1.00
78_T	83_M	0.839	1.00
58_S	62_C	0.836	1.00
282_G	292_S	0.834	1.00
90_I	105_K	0.832	1.00
163_V	167_L	0.832	1.00
11_I	14_A	0.830	1.00
63_G	249_P	0.828	1.00
46_L	176_K	0.825	1.00
49_L	276_L	0.822	1.00
195_Y	226_I	0.822	1.00
111_V	115_A	0.818	1.00
196_A	261_K	0.817	1.00
206_E	216_Y	0.817	1.00
121_M	221_N	0.817	1.00
161_Q	164_S	0.816	1.00
11_I	15_V	0.813	1.00
35_K	39_S	0.811	1.00
21_G	45_R	0.811	1.00
57_L	186_I	0.807	1.00
216_Y	220_V	0.799	1.00
104_I	107_L	0.799	1.00
252_V	256_R	0.799	1.00
54_I	186_I	0.793	1.00
253_S	263_S	0.787	1.00
183_Y	187_P	0.786	1.00
269_L	273_V	0.785	1.00
12_I	15_V	0.783	1.00
110_F	114_L	0.782	1.00
299_I	303_G	0.781	1.00
20_I	24_D	0.779	1.00
93_S	105_K	0.779	1.00
224_L	228_S	0.778	1.00
284_I	287_F	0.775	1.00
122_K	125_E	0.772	1.00
192_A	223_G	0.771	1.00
260_L	265_P	0.770	1.00
84_D	87_R	0.769	1.00
286_I	291_I	0.768	1.00
114_L	232_S	0.767	1.00
182_L	233_L	0.766	1.00
39_S	42_F	0.764	1.00
60_S	64_L	0.762	1.00
85_W	146_V	0.761	1.00
82_T	117_N	0.758	1.00
92_I	149_I	0.755	1.00
76_S	79_T	0.755	1.00
209_S	216_Y	0.754	1.00
244_L	297_V	0.753	1.00
275_V	297_V	0.752	1.00
194_V	198_K	0.750	1.00
50_I	54_I	0.748	1.00
193_Y	196_A	0.745	1.00
252_V	255_Y	0.745	1.00
120_F	124_L	0.744	1.00
34_S	38_A	0.743	1.00
48_R	283_R	0.743	1.00
285_I	288_P	0.741	1.00
51_S	182_L	0.740	1.00
6_L	10_L	0.738	1.00
25_L	37_E	0.736	1.00
187_P	190_I	0.736	1.00
198_K	214_L	0.734	1.00
66_M	80_A	0.733	1.00
23_E	27_P	0.732	1.00
307_F	311_R	0.726	1.00
92_I	97_F	0.723	1.00
48_R	290_E	0.719	1.00
189_V	193_Y	0.717	1.00
91_L	154_A	0.714	1.00
233_L	236_L	0.713	1.00
17_S	283_R	0.713	1.00
60_S	268_V	0.712	1.00
59_M	244_L	0.712	1.00
10_L	14_A	0.711	1.00
117_N	224_L	0.710	1.00
254_I	308_M	0.708	1.00
272_A	276_L	0.707	1.00
61_I	192_A	0.706	1.00
186_I	234_V	0.705	1.00
200_T	265_P	0.703	1.00
27_P	30_L	0.701	1.00
275_V	293_I	0.700	1.00
182_L	185_S	0.699	1.00
125_E	130_N	0.699	1.00
29_D	33_L	0.699	1.00
87_R	240_M	0.698	1.00
10_L	276_L	0.697	1.00
113_A	228_S	0.696	1.00
233_L	237_T	0.695	1.00
202_A	216_Y	0.692	1.00
105_K	108_V	0.690	1.00
18_V	41_L	0.690	1.00
114_L	228_S	0.690	1.00
62_C	231_T	0.689	1.00
70_S	136_P	0.689	1.00
121_M	217_K	0.685	1.00
94_L	162_N	0.685	1.00
210_V	216_Y	0.683	1.00
18_V	46_L	0.680	1.00
251_I	270_L	0.678	1.00
123_I	138_V	0.676	1.00
154_A	164_S	0.676	1.00
127_I	134_F	0.675	1.00
61_I	264_L	0.675	1.00
41_L	46_L	0.674	1.00
103_L	107_L	0.674	1.00
171_F	293_I	0.673	1.00
116_G	120_F	0.670	1.00
251_I	254_I	0.668	1.00
278_C	296_M	0.661	1.00
244_L	274_F	0.660	1.00
93_S	104_I	0.659	1.00
151_T	155_Y	0.655	1.00
147_S	167_L	0.655	1.00
185_S	229_L	0.654	1.00
39_S	44_S	0.654	1.00
241_L	293_I	0.653	1.00
65_I	226_I	0.652	1.00
68_Q	203_G	0.651	1.00
157_Y	160_I	0.646	1.00
20_I	280_I	0.644	1.00
164_S	167_L	0.641	1.00
274_F	278_C	0.640	1.00
249_P	267_T	0.639	1.00
12_I	16_T	0.637	1.00
84_D	143_G	0.635	1.00
57_L	61_I	0.632	1.00
222_I	226_I	0.632	1.00
151_T	166_W	0.631	1.00
198_K	201_L	0.631	1.00
223_G	227_V	0.629	1.00
46_L	50_I	0.629	1.00
176_K	180_E	0.628	1.00
247_I	305_F	0.628	1.00
159_L	162_N	0.627	1.00
133_I	136_P	0.627	1.00
247_I	251_I	0.626	1.00
265_P	269_L	0.624	1.00
89_G	93_S	0.624	1.00
274_F	300_I	0.624	1.00
28_L	31_F	0.624	1.00
17_S	276_L	0.623	1.00
122_K	126_R	0.623	1.00
15_V	31_F	0.620	1.00
55_A	171_F	0.619	1.00
76_S	245_G	0.617	1.00
251_I	274_F	0.616	1.00
66_M	75_V	0.615	1.00
94_L	163_V	0.615	1.00
23_E	26_S	0.614	1.00
268_V	272_A	0.612	1.00
147_S	151_T	0.611	1.00
83_M	86_A	0.611	1.00
119_L	122_K	0.610	1.00
5_Y	9_L	0.609	1.00
138_V	141_M	0.608	1.00
171_F	238_V	0.608	1.00
27_P	31_F	0.608	1.00
222_I	225_I	0.606	1.00
277_F	280_I	0.605	1.00
66_M	82_T	0.603	1.00
179_Y	182_L	0.603	1.00
115_A	118_F	0.603	1.00
197_D	200_T	0.602	1.00
251_I	304_I	0.602	1.00
282_G	290_E	0.597	1.00
131_D	134_F	0.596	1.00
177_G	181_L	0.596	1.00
310_L	313_K	0.595	1.00
202_A	219_V	0.595	1.00
13_L	16_T	0.595	1.00
93_S	97_F	0.592	1.00
111_V	114_L	0.592	1.00
231_T	235_I	0.592	1.00
26_S	37_E	0.591	1.00
194_V	197_D	0.590	1.00
247_I	304_I	0.589	1.00
186_I	190_I	0.589	1.00
246_L	308_M	0.588	1.00
112_F	116_G	0.583	1.00
282_G	285_I	0.582	1.00
52_I	293_I	0.580	0.99
121_M	125_E	0.580	0.99
84_D	147_S	0.579	0.99
25_L	40_T	0.579	0.99
124_L	138_V	0.578	0.99
116_G	142_L	0.577	0.99
200_T	203_G	0.576	0.99
19_F	31_F	0.574	0.99
51_S	55_A	0.574	0.99
186_I	189_V	0.571	0.99
117_N	121_M	0.571	0.99
70_S	73_K	0.569	0.99
228_S	232_S	0.569	0.99
71_R	206_E	0.569	0.99
51_S	238_V	0.566	0.99
64_L	252_V	0.566	0.99
215_K	222_I	0.564	0.99
261_K	265_P	0.563	0.99
270_L	273_V	0.563	0.99
16_T	280_I	0.561	0.99
192_A	264_L	0.559	0.99
65_I	227_V	0.559	0.99
232_S	236_L	0.558	0.99
17_S	21_G	0.558	0.99
154_A	160_I	0.555	0.99
279_D	290_E	0.554	0.99
276_L	280_I	0.552	0.99
148_S	298_G	0.551	0.99
25_L	33_L	0.550	0.99
179_Y	183_Y	0.545	0.99
181_L	185_S	0.544	0.99
199_F	264_L	0.543	0.99
257_G	265_P	0.543	0.99
280_I	284_I	0.543	0.99
24_D	28_L	0.543	0.99
5_Y	8_I	0.542	0.99
162_N	165_S	0.541	0.99
60_S	271_G	0.540	0.99
124_L	130_N	0.540	0.99
102_P	106_M	0.537	0.99
82_T	120_F	0.537	0.99
154_A	163_V	0.534	0.99
215_K	221_N	0.533	0.99
14_A	50_I	0.532	0.99
181_L	233_L	0.529	0.99
96_L	99_S	0.529	0.99
161_Q	167_L	0.526	0.99
307_F	310_L	0.526	0.99
90_I	108_V	0.526	0.99
124_L	135_I	0.525	0.99
145_I	149_I	0.525	0.99
165_S	170_D	0.524	0.99
251_I	255_Y	0.522	0.99
36_Q	40_T	0.522	0.99
82_T	170_D	0.522	0.99
155_Y	168_Q	0.521	0.99
85_W	142_L	0.520	0.99
189_V	268_V	0.518	0.99
119_L	142_L	0.515	0.99
22_V	288_P	0.515	0.99
188_L	191_I	0.515	0.99
75_V	82_T	0.515	0.99
138_V	142_L	0.514	0.99
126_R	134_F	0.513	0.99
66_M	228_S	0.509	0.99
252_V	267_T	0.509	0.99
248_I	278_C	0.508	0.99
250_N	253_S	0.508	0.99
7_F	10_L	0.506	0.99
105_K	109_A	0.506	0.99
199_F	260_L	0.506	0.99
61_I	230_I	0.505	0.99
7_F	266_H	0.501	0.99
14_A	18_V	0.500	0.99
23_E	37_E	0.500	0.99

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2nq2A	2	0.9557	100	0.166	Contact Map
2qi9A	2	0.9747	100	0.168	Contact Map
4g1uA	2	0.9114	100	0.169	Contact Map
4f35D	2	0.6361	10.1	0.967	Contact Map
2l9uA	2	0.0918	6.4	0.97	Contact Map
2m20A	2	0.0918	6.3	0.97	Contact Map
3wdoA	1	0.8987	5.9	0.97	Contact Map
2kluA	1	0.1266	3.6	0.973	Contact Map
4gxbB	1	0.0032	3.2	0.974	Contact Map
2l2tA	2	0.1171	3.2	0.974	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0105 seconds.