YCLK - BACSU - GREMLIN Contacts

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YCLK - Sensor histidine kinase YclK

UniProt:	P94414	Sequences: MMKIKYLYQLLLSHISILILAFVIIISLFSHFVKEFAYQNKVEELTSYAVQIANEFQSGQVDMRRLYPYQDILSTRKTQFIIFNEEQQPYFLPEGFHHPPREQLKKSEWNKLKKGQTVTIRADGRFDDEVSLVAQPIFVQNEFKGAVLLISPISGVEQMVNQVNLYMFYAVISTLVITILVSWLLSKFHVKRIQKLREATDKVASGDYDIHLENSYGDEIGVLASDFNIMAKKLKQSRDEIERLEKRRRQFIADVSHELKTPLTTINGLVEGLNSHTIPEDKKDKCFSLISEETKRMLRLVKENLDYEKIRSQQITLNKLDVPLIEVFEIVKEHLQQQAEEKQNKLMIQVEDHVIVHADYDRFIQILVNITKNSIQFTQNGDIWLRGMEGYKETIIEIEDTGIGIPKEDIEHIWERFYKADISRTNTAYGEYGLGLSIVRQLVEMHQGTVEIKSEEGKGTKFIIRLPLTAKQQ	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	473 (438)
Sequences:	50988 (44628)
Seq/√Len:	2132.4

ECOLI - BARA TORS BAES CUSS GLRK CREC YEDV PHOQ CPXA QSEC RSTB ENVZ ATOS RCSC RCSD DCUS ARCB ZRAS EVGS NARX NARQ DPIB BASS KDPD PHOR YPDA NTRB UHPB
BACSU - YCLK YYCG YKOH RESE YVRG CSSS PHOR YVCQ DCTS YRKQ KINB MALK CITS KIND KINE YCBM YXDK BCES YESM KINA GLNK LIAS KINC YBDK COMP LYTS YWPD YHCY DEGS NATK YFIJ YXJM
HALSA - Q9HQ15 Q9HQE9 Q9HQG5 Q9HQ16 O51970 Q9HR10 Q9HRG1 Q9HRE4 Q9HNM2 BAT Q9HQB9 Q9HNA6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
399_E	461_K	3.977	1.00
400_D	404_G	3.885	1.00
322_V	358_A	3.710	1.00
393_E	465_R	3.635	1.00
440_R	444_E	3.596	1.00
451_E	463_I	3.539	1.00
397_E	461_K	3.322	1.00
270_V	290_I	3.294	1.00
386_R	397_E	2.994	1.00
347_M	384_W	2.950	1.00
397_E	463_I	2.922	1.00
410_I	454_S	2.863	1.00
395_I	465_R	2.848	1.00
395_I	463_I	2.820	1.00
274_N	291_S	2.724	1.00
347_M	382_D	2.700	1.00
382_D	401_T	2.690	1.00
388_M	395_I	2.686	1.00
358_A	446_H	2.655	1.00
321_D	357_H	2.635	1.00
384_W	399_E	2.629	1.00
452_I	462_F	2.575	1.00
349_Q	386_R	2.555	1.00
406_P	409_D	2.541	1.00
453_K	463_I	2.523	1.00
267_N	295_K	2.501	1.00
439_V	450_V	2.464	1.00
388_M	397_E	2.419	1.00
321_D	355_I	2.417	1.00
455_E	458_K	2.410	1.00
453_K	461_K	2.408	1.00
274_N	288_S	2.366	1.00
366_I	443_V	2.364	1.00
378_T	401_T	2.360	1.00
386_R	399_E	2.350	1.00
405_I	413_I	2.331	1.00
323_P	326_E	2.272	1.00
410_I	452_I	2.261	1.00
414_W	450_V	2.223	1.00
443_V	448_G	2.209	1.00
409_D	412_H	2.209	1.00
267_N	294_T	2.195	1.00
449_T	465_R	2.188	1.00
330_I	364_I	2.166	1.00
349_Q	384_W	2.160	1.00
227_F	231_A	2.098	1.00
335_L	368_V	2.096	1.00
345_K	382_D	2.030	1.00
298_L	302_K	2.022	1.00
454_S	460_T	2.014	1.00
320_L	360_Y	2.000	1.00
443_V	464_I	1.992	1.00
267_N	298_L	1.980	1.00
407_K	410_I	1.955	1.00
451_E	465_R	1.925	1.00
319_K	357_H	1.913	1.00
412_H	415_E	1.892	1.00
412_H	418_Y	1.847	1.00
245_E	248_R	1.842	1.00
366_I	439_V	1.828	1.00
390_G	395_I	1.813	1.00
366_I	442_L	1.811	1.00
372_K	376_Q	1.809	1.00
228_N	231_A	1.809	1.00
381_G	401_T	1.807	1.00
218_D	221_G	1.804	1.00
409_D	418_Y	1.803	1.00
358_A	363_F	1.800	1.00
339_A	375_I	1.770	1.00
250_Q	254_D	1.755	1.00
280_E	283_K	1.748	1.00
442_L	446_H	1.734	1.00
405_I	409_D	1.714	1.00
271_E	291_S	1.701	1.00
27_S	31_H	1.683	1.00
367_L	396_I	1.676	1.00
269_L	286_C	1.675	1.00
409_D	420_A	1.659	1.00
202_K	207_D	1.640	1.00
359_D	362_R	1.629	1.00
227_F	230_M	1.614	1.00
444_E	449_T	1.600	1.00
378_T	381_G	1.596	1.00
405_I	460_T	1.589	1.00
274_N	284_D	1.582	1.00
291_S	295_K	1.573	1.00
217_G	221_G	1.565	1.00
270_V	291_S	1.548	1.00
244_L	248_R	1.541	1.00
325_I	329_E	1.536	1.00
243_R	247_R	1.534	1.00
384_W	401_T	1.528	1.00
246_K	250_Q	1.525	1.00
266_I	294_T	1.500	1.00
362_R	365_Q	1.499	1.00
369_N	439_V	1.496	1.00
273_L	287_F	1.484	1.00
216_Y	221_G	1.464	1.00
414_W	452_I	1.448	1.00
396_I	464_I	1.444	1.00
360_Y	364_I	1.442	1.00
400_D	459_G	1.438	1.00
415_E	418_Y	1.420	1.00
334_H	364_I	1.417	1.00
406_P	456_E	1.416	1.00
267_N	291_S	1.411	1.00
443_V	450_V	1.407	1.00
265_T	293_E	1.404	1.00
410_I	414_W	1.394	1.00
332_K	348_I	1.387	1.00
197_R	201_D	1.382	1.00
197_R	222_V	1.379	1.00
454_S	457_G	1.373	1.00
258_E	365_Q	1.365	1.00
366_I	464_I	1.363	1.00
279_P	282_K	1.351	1.00
330_I	360_Y	1.350	1.00
265_T	269_L	1.340	1.00
203_V	231_A	1.339	1.00
454_S	458_K	1.338	1.00
323_P	355_I	1.338	1.00
336_Q	340_E	1.334	1.00
325_I	387_G	1.334	1.00
84_N	88_Q	1.318	1.00
329_E	348_I	1.294	1.00
441_Q	444_E	1.287	1.00
248_R	252_I	1.272	1.00
207_D	210_I	1.256	1.00
338_Q	341_E	1.254	1.00
362_R	445_M	1.254	1.00
362_R	442_L	1.253	1.00
194_Q	197_R	1.243	1.00
413_I	452_I	1.240	1.00
245_E	249_R	1.236	1.00
327_V	331_V	1.231	1.00
254_D	416_R	1.228	1.00
269_L	289_L	1.222	1.00
266_I	290_I	1.217	1.00
200_T	203_V	1.207	1.00
226_D	229_I	1.206	1.00
270_V	294_T	1.195	1.00
288_S	292_E	1.190	1.00
299_R	361_D	1.185	1.00
211_H	232_K	1.180	1.00
224_A	228_N	1.176	1.00
419_K	429_Y	1.174	1.00
452_I	460_T	1.173	1.00
369_N	372_K	1.171	1.00
302_K	306_D	1.167	1.00
377_F	419_K	1.162	1.00
165_L	169_Y	1.161	1.00
325_I	350_V	1.156	1.00
350_V	387_G	1.151	1.00
448_G	466_L	1.151	1.00
230_M	234_L	1.141	1.00
363_F	446_H	1.140	1.00
251_F	255_V	1.139	1.00
328_F	387_G	1.129	1.00
34_K	38_Y	1.126	1.00
414_W	440_R	1.125	1.00
273_L	283_K	1.122	1.00
260_K	302_K	1.121	1.00
331_V	368_V	1.120	1.00
246_K	249_R	1.115	1.00
220_I	223_L	1.115	1.00
182_S	186_S	1.115	1.00
28_L	32_F	1.114	1.00
202_K	210_I	1.113	1.00
331_V	335_L	1.106	1.00
265_T	268_G	1.106	1.00
393_E	449_T	1.098	1.00
270_V	274_N	1.094	1.00
407_K	454_S	1.092	1.00
317_L	359_D	1.091	1.00
351_E	388_M	1.086	1.00
285_K	289_L	1.073	1.00
289_L	293_E	1.067	1.00
197_R	200_T	1.064	1.00
322_V	327_V	1.063	1.00
414_W	462_F	1.063	1.00
374_S	383_I	1.059	1.00
305_L	308_E	1.057	1.00
319_K	446_H	1.051	1.00
399_E	455_E	1.050	1.00
200_T	204_A	1.048	1.00
370_I	462_F	1.046	1.00
210_I	213_E	1.044	1.00
268_G	272_G	1.043	1.00
229_I	233_K	1.042	1.00
230_M	233_K	1.040	1.00
81_I	148_L	1.040	1.00
279_P	283_K	1.038	1.00
364_I	368_V	1.031	1.00
416_R	441_Q	1.028	1.00
405_I	410_I	1.025	1.00
153_I	157_E	1.025	1.00
332_K	336_Q	1.025	1.00
293_E	296_R	1.023	1.00
250_Q	416_R	1.023	1.00
400_D	460_T	1.019	1.00
280_E	284_D	1.014	1.00
224_A	227_F	1.007	1.00
331_V	364_I	1.004	1.00
104_L	109_W	1.001	1.00
334_H	368_V	0.997	1.00
196_L	200_T	0.997	1.00
405_I	452_I	0.996	1.00
390_G	393_E	0.993	1.00
200_T	226_D	0.991	1.00
244_L	247_R	0.991	1.00
371_T	385_L	0.990	1.00
294_T	298_L	0.990	1.00
70_Q	74_S	0.989	1.00
258_E	369_N	0.981	1.00
45_L	49_A	0.980	1.00
270_V	287_F	0.980	1.00
370_I	450_V	0.980	1.00
327_V	358_A	0.978	1.00
42_V	46_T	0.977	1.00
186_S	190_V	0.974	1.00
200_T	227_F	0.972	1.00
83_F	89_P	0.972	1.00
26_I	30_S	0.970	1.00
223_L	227_F	0.970	1.00
48_Y	51_Q	0.969	1.00
81_I	89_P	0.968	1.00
276_H	283_K	0.963	1.00
9_Q	218_D	0.961	1.00
199_A	212_L	0.961	1.00
367_L	398_I	0.960	1.00
303_E	362_R	0.959	1.00
299_R	303_E	0.955	1.00
284_D	288_S	0.954	1.00
267_N	271_E	0.952	1.00
335_L	371_T	0.947	1.00
109_W	112_L	0.947	1.00
180_L	184_L	0.947	1.00
326_E	330_I	0.945	1.00
220_I	224_A	0.944	1.00
367_L	371_T	0.943	1.00
377_F	403_I	0.942	1.00
189_H	192_R	0.942	1.00
65_R	68_P	0.942	1.00
370_I	439_V	0.930	1.00
324_L	396_I	0.929	1.00
368_V	372_K	0.928	1.00
216_Y	224_A	0.922	1.00
260_K	298_L	0.917	1.00
31_H	35_E	0.917	1.00
404_G	460_T	0.915	1.00
361_D	364_I	0.915	1.00
46_T	50_V	0.913	1.00
197_R	226_D	0.908	1.00
41_K	44_E	0.907	1.00
31_H	34_K	0.906	1.00
49_A	53_A	0.904	1.00
338_Q	372_K	0.901	1.00
441_Q	445_M	0.901	1.00
210_I	214_N	0.898	1.00
413_I	462_F	0.897	1.00
288_S	291_S	0.896	1.00
378_T	383_I	0.896	1.00
345_K	348_I	0.896	1.00
317_L	362_R	0.895	1.00
214_N	225_S	0.894	1.00
105_K	108_E	0.892	1.00
261_T	265_T	0.882	1.00
179_I	183_W	0.881	1.00
204_A	229_I	0.880	1.00
439_V	443_V	0.879	1.00
405_I	411_E	0.876	1.00
257_H	369_N	0.875	1.00
38_Y	42_V	0.872	1.00
434_L	438_I	0.870	1.00
290_I	294_T	0.867	1.00
66_L	69_Y	0.864	1.00
161_N	165_L	0.863	1.00
390_G	465_R	0.862	1.00
252_I	255_V	0.860	1.00
264_T	268_G	0.860	1.00
344_N	348_I	0.858	1.00
295_K	298_L	0.853	1.00
66_L	72_I	0.850	1.00
201_D	222_V	0.849	1.00
231_A	235_K	0.848	1.00
30_S	164_N	0.847	1.00
319_K	447_Q	0.845	1.00
258_E	262_P	0.845	1.00
443_V	466_L	0.844	1.00
202_K	206_G	0.843	1.00
440_R	449_T	0.841	1.00
365_Q	442_L	0.837	1.00
211_H	228_N	0.836	1.00
89_P	92_L	0.835	1.00
221_G	225_S	0.834	1.00
221_G	224_A	0.832	1.00
370_I	464_I	0.831	1.00
38_Y	41_K	0.831	1.00
134_A	146_A	0.830	1.00
201_D	205_S	0.830	1.00
335_L	372_K	0.830	1.00
285_K	288_S	0.827	1.00
136_P	146_A	0.826	1.00
184_L	188_F	0.826	1.00
306_D	365_Q	0.824	1.00
331_V	371_T	0.824	1.00
49_A	52_I	0.824	1.00
448_G	464_I	0.822	1.00
62_D	66_L	0.816	1.00
269_L	290_I	0.816	1.00
79_Q	92_L	0.810	1.00
213_E	228_N	0.809	1.00
329_E	333_E	0.807	1.00
337_Q	341_E	0.802	1.00
319_K	358_A	0.801	1.00
328_F	385_L	0.799	1.00
69_Y	73_L	0.797	1.00
66_L	70_Q	0.797	1.00
292_E	330_I	0.795	1.00
165_L	168_F	0.795	1.00
257_H	261_T	0.793	1.00
329_E	332_K	0.792	1.00
344_N	378_T	0.792	1.00
317_L	445_M	0.790	1.00
145_G	149_L	0.789	1.00
44_E	47_S	0.788	1.00
78_T	81_I	0.787	1.00
138_F	143_F	0.785	1.00
371_T	383_I	0.785	1.00
63_M	66_L	0.783	1.00
183_W	187_K	0.782	1.00
40_N	44_E	0.780	1.00
192_R	196_L	0.780	1.00
272_G	276_H	0.778	1.00
243_R	246_K	0.777	1.00
343_Q	380_N	0.775	1.00
303_E	365_Q	0.774	1.00
39_Q	42_V	0.774	1.00
289_L	292_E	0.771	1.00
194_Q	198_E	0.770	1.00
328_F	367_L	0.768	1.00
156_V	160_V	0.768	1.00
43_E	46_T	0.768	1.00
231_A	234_L	0.767	1.00
331_V	334_H	0.766	1.00
130_V	134_A	0.765	1.00
223_L	226_D	0.764	1.00
160_V	164_N	0.761	1.00
71_D	74_S	0.761	1.00
79_Q	150_I	0.760	1.00
259_L	297_M	0.759	1.00
83_F	148_L	0.757	1.00
62_D	65_R	0.755	1.00
199_A	210_I	0.754	1.00
222_V	225_S	0.753	1.00
30_S	34_K	0.751	1.00
44_E	48_Y	0.751	1.00
337_Q	340_E	0.750	1.00
269_L	293_E	0.750	1.00
198_E	202_K	0.750	1.00
41_K	45_L	0.749	1.00
201_D	226_D	0.749	1.00
413_I	437_S	0.749	1.00
385_L	398_I	0.748	1.00
17_I	21_A	0.748	1.00
315_I	362_R	0.746	1.00
333_E	336_Q	0.745	1.00
278_I	283_K	0.742	1.00
161_N	164_N	0.742	1.00
330_I	334_H	0.741	1.00
40_N	43_E	0.739	1.00
187_K	191_K	0.738	1.00
274_N	287_F	0.738	1.00
36_F	40_N	0.736	1.00
286_C	290_I	0.734	1.00
146_A	150_I	0.733	1.00
322_V	360_Y	0.733	1.00
307_Y	437_S	0.733	1.00
400_D	403_I	0.732	1.00
264_T	267_N	0.730	1.00
203_V	230_M	0.729	1.00
438_I	442_L	0.729	1.00
37_A	40_N	0.728	1.00
45_L	48_Y	0.728	1.00
362_R	366_I	0.725	1.00
212_L	228_N	0.724	1.00
339_A	383_I	0.723	1.00
324_L	356_V	0.721	1.00
338_Q	342_K	0.719	1.00
344_N	375_I	0.719	1.00
397_E	453_K	0.718	1.00
228_N	232_K	0.717	1.00
366_I	446_H	0.716	1.00
249_R	311_R	0.715	1.00
403_I	429_Y	0.714	1.00
211_H	231_A	0.713	1.00
107_S	111_K	0.711	1.00
405_I	454_S	0.708	1.00
419_K	431_E	0.708	1.00
339_A	342_K	0.705	1.00
296_R	364_I	0.702	1.00
142_E	145_G	0.702	1.00
265_T	289_L	0.700	1.00
393_E	467_P	0.700	1.00
370_I	443_V	0.699	1.00
410_I	462_F	0.697	1.00
276_H	282_K	0.697	1.00
141_N	144_K	0.696	1.00
374_S	398_I	0.696	1.00
306_D	362_R	0.694	1.00
130_V	150_I	0.694	1.00
211_H	214_N	0.691	1.00
318_N	359_D	0.691	1.00
362_R	446_H	0.689	1.00
287_F	291_S	0.688	1.00
305_L	309_K	0.688	1.00
322_V	357_H	0.688	1.00
387_G	394_T	0.687	1.00
209_D	235_K	0.687	1.00
407_K	411_E	0.685	1.00
132_L	135_Q	0.685	1.00
106_K	110_N	0.684	1.00
332_K	346_L	0.684	1.00
164_N	168_F	0.683	1.00
334_H	338_Q	0.682	1.00
23_V	27_S	0.682	1.00
218_D	222_V	0.679	1.00
52_I	55_E	0.677	1.00
166_Y	169_Y	0.677	1.00
214_N	217_G	0.677	1.00
47_S	50_V	0.677	1.00
258_E	438_I	0.677	1.00
252_I	256_S	0.675	1.00
448_G	467_P	0.675	1.00
212_L	224_A	0.675	1.00
298_L	301_V	0.673	1.00
42_V	45_L	0.672	1.00
84_N	90_Y	0.671	1.00
43_E	47_S	0.668	1.00
255_V	304_N	0.668	1.00
188_F	191_K	0.668	1.00
168_F	172_I	0.667	1.00
324_L	394_T	0.665	1.00
130_V	133_V	0.665	1.00
226_D	230_M	0.664	1.00
156_V	159_M	0.664	1.00
329_E	350_V	0.663	1.00
409_D	422_I	0.663	1.00
107_S	110_N	0.661	1.00
190_V	194_Q	0.661	1.00
50_V	53_A	0.660	1.00
67_Y	70_Q	0.660	1.00
339_A	346_L	0.659	1.00
395_I	451_E	0.659	1.00
193_I	197_R	0.658	1.00
92_L	96_F	0.656	1.00
202_K	205_S	0.656	1.00
108_E	113_K	0.656	1.00
63_M	67_Y	0.655	1.00
410_I	453_K	0.652	1.00
199_A	202_K	0.652	1.00
407_K	455_E	0.652	1.00
354_V	387_G	0.651	1.00
102_E	106_K	0.648	1.00
51_Q	55_E	0.648	1.00
351_E	387_G	0.647	1.00
283_K	286_C	0.647	1.00
376_Q	429_Y	0.647	1.00
335_L	375_I	0.646	1.00
39_Q	43_E	0.645	1.00
291_S	294_T	0.643	1.00
214_N	224_A	0.643	1.00
365_Q	368_V	0.642	1.00
383_I	398_I	0.641	1.00
253_A	256_S	0.641	1.00
223_L	230_M	0.640	1.00
157_E	161_N	0.640	1.00
192_R	197_R	0.640	1.00
376_Q	431_E	0.637	1.00
333_E	337_Q	0.636	1.00
340_E	343_Q	0.634	1.00
297_M	301_V	0.633	1.00
259_L	262_P	0.633	1.00
451_E	464_I	0.632	1.00
327_V	364_I	0.632	1.00
216_Y	220_I	0.632	1.00
332_K	385_L	0.631	1.00
277_T	283_K	0.631	1.00
258_E	300_L	0.630	1.00
387_G	396_I	0.628	1.00
157_E	160_V	0.627	1.00
405_I	462_F	0.627	1.00
193_I	196_L	0.626	1.00
278_I	282_K	0.626	1.00
439_V	442_L	0.626	1.00
42_V	131_S	0.625	1.00
113_K	116_Q	0.624	1.00
172_I	176_V	0.623	1.00
191_K	195_K	0.623	1.00
166_Y	170_A	0.623	1.00
201_D	204_A	0.622	1.00
263_L	301_V	0.618	1.00
195_K	199_A	0.618	1.00
35_E	38_Y	0.617	1.00
186_S	189_H	0.616	1.00
327_V	363_F	0.616	1.00
450_V	462_F	0.616	1.00
196_L	224_A	0.616	1.00
273_L	286_C	0.616	1.00
339_A	344_N	0.616	1.00
406_P	420_A	0.615	1.00
115_G	118_V	0.614	1.00
295_K	299_R	0.613	1.00
325_I	352_D	0.613	1.00
133_V	136_P	0.613	1.00
437_S	441_Q	0.612	1.00
162_Q	166_Y	0.610	1.00
24_I	28_L	0.609	1.00
419_K	430_G	0.609	1.00
178_T	182_S	0.609	1.00
50_V	54_N	0.607	1.00
32_F	36_F	0.607	1.00
216_Y	223_L	0.605	1.00
195_K	198_E	0.605	1.00
281_D	284_D	0.604	1.00
293_E	334_H	0.602	1.00
384_W	387_G	0.602	1.00
16_S	19_I	0.602	1.00
118_V	122_A	0.602	1.00
110_N	113_K	0.601	1.00
204_A	233_K	0.599	1.00
32_F	35_E	0.596	1.00
110_N	114_K	0.596	1.00
272_G	286_C	0.592	1.00
351_E	386_R	0.592	1.00
269_L	294_T	0.590	1.00
134_A	137_I	0.587	1.00
399_E	457_G	0.586	1.00
276_H	279_P	0.585	1.00
204_A	207_D	0.585	1.00
84_N	87_Q	0.584	1.00
34_K	37_A	0.584	1.00
276_H	286_C	0.583	1.00
104_L	108_E	0.583	1.00
36_F	39_Q	0.583	1.00
35_E	39_Q	0.581	1.00
69_Y	72_I	0.578	1.00
200_T	223_L	0.578	1.00
351_E	354_V	0.577	1.00
325_I	353_H	0.577	1.00
204_A	208_Y	0.576	1.00
64_R	67_Y	0.576	1.00
326_E	360_Y	0.576	1.00
254_D	258_E	0.575	1.00
158_Q	162_Q	0.573	1.00
349_Q	388_M	0.573	1.00
27_S	30_S	0.572	1.00
410_I	460_T	0.572	1.00
167_M	171_V	0.571	1.00
188_F	192_R	0.571	1.00
144_K	148_L	0.570	1.00
64_R	68_P	0.568	1.00
406_P	410_I	0.568	1.00
423_S	429_Y	0.567	1.00
339_A	343_Q	0.567	1.00
307_Y	441_Q	0.566	1.00
191_K	194_Q	0.566	1.00
14_H	182_S	0.565	1.00
33_V	36_F	0.565	1.00
132_L	150_I	0.565	1.00
153_I	156_V	0.564	1.00
266_I	270_V	0.563	1.00
108_E	111_K	0.563	1.00
219_E	223_L	0.562	1.00
19_I	23_V	0.561	1.00
251_F	258_E	0.561	1.00
124_G	128_D	0.561	1.00
119_T	122_A	0.560	1.00
306_D	309_K	0.559	1.00
266_I	293_E	0.558	1.00
102_E	105_K	0.558	1.00
211_H	235_K	0.555	1.00
323_P	353_H	0.554	1.00
131_S	134_A	0.553	1.00
297_M	305_L	0.552	1.00
109_W	113_K	0.552	1.00
15_I	18_L	0.552	1.00
160_V	163_V	0.550	1.00
219_E	224_A	0.549	1.00
286_C	289_L	0.549	1.00
335_L	338_Q	0.546	1.00
65_R	73_L	0.546	1.00
67_Y	71_D	0.544	1.00
134_A	148_L	0.543	1.00
303_E	361_D	0.543	1.00
13_S	17_I	0.542	1.00
417_F	437_S	0.542	1.00
192_R	200_T	0.540	1.00
415_E	440_R	0.540	1.00
14_H	17_I	0.540	1.00
192_R	195_K	0.539	1.00
47_S	51_Q	0.539	1.00
261_T	268_G	0.539	1.00
423_S	430_G	0.538	1.00
120_I	123_D	0.538	1.00
94_E	97_H	0.538	1.00
103_Q	108_E	0.538	1.00
271_E	274_N	0.537	1.00
282_K	286_C	0.536	1.00
247_R	250_Q	0.536	1.00
256_S	262_P	0.535	1.00
258_E	261_T	0.534	1.00
327_V	330_I	0.534	1.00
264_T	269_L	0.532	1.00
414_W	417_F	0.532	1.00
79_Q	82_I	0.532	1.00
413_I	418_Y	0.532	1.00
155_G	158_Q	0.531	1.00
311_R	441_Q	0.531	1.00
403_I	460_T	0.529	1.00
222_V	226_D	0.527	1.00
169_Y	173_S	0.527	1.00
443_V	449_T	0.526	1.00
332_K	335_L	0.526	1.00
200_T	206_G	0.523	1.00
411_E	415_E	0.522	1.00
111_K	115_G	0.522	1.00
296_R	300_L	0.521	1.00
167_M	170_A	0.521	1.00
262_P	297_M	0.520	1.00
363_F	367_L	0.519	1.00
269_L	273_L	0.519	1.00
293_E	297_M	0.518	1.00
224_A	231_A	0.518	1.00
81_I	92_L	0.517	1.00
304_N	417_F	0.516	1.00
119_T	123_D	0.516	1.00
93_P	96_F	0.514	1.00
259_L	301_V	0.514	1.00
251_F	256_S	0.511	1.00
129_E	132_L	0.511	1.00
48_Y	52_I	0.509	1.00
376_Q	419_K	0.509	1.00
325_I	348_I	0.508	1.00
271_E	275_S	0.507	1.00
28_L	31_H	0.507	1.00
269_L	272_G	0.507	1.00
135_Q	138_F	0.505	1.00
68_P	71_D	0.505	1.00
195_K	213_E	0.503	1.00
317_L	446_H	0.503	1.00
294_T	297_M	0.503	1.00
103_Q	107_S	0.502	1.00
261_T	264_T	0.502	1.00
225_S	229_I	0.502	1.00
203_V	206_G	0.502	1.00
16_S	23_V	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4i5sA	2	0.5899	100	0.332	Contact Map
4bixA	2	0.482	100	0.387	Contact Map
4ctiA	2	0.482	100	0.425	Contact Map
4q20A	2	0.4841	100	0.462	Contact Map
3a0rA	2	0.6956	100	0.463	Contact Map
4mpcA	2	0.6427	100	0.47	Contact Map
3jz3A	2	0.3383	100	0.473	Contact Map
4e01A	3	0.6216	100	0.477	Contact Map
2c2aA	2	0.4905	100	0.479	Contact Map
4gczA	2	0.7505	100	0.48	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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