GREMLIN Database
YCLG - Uncharacterized protein YclG
UniProt: P94409 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 584 (467)
Sequences: 191 (179)
Seq/√Len: 8.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
342_N365_N5.9241.00
244_N267_N5.3861.00
76_M108_G4.6510.99
26_N30_S4.2560.98
204_C244_N3.9710.97
15_R21_S3.7620.96
267_N286_N3.7290.96
12_G17_G3.6390.96
286_N321_N3.6230.96
21_S24_R3.4880.95
464_N487_N3.3770.93
342_N393_N3.3530.93
13_V24_R3.2870.93
71_N102_N3.2560.92
217_P222_D3.2520.92
321_N342_N3.2310.92
15_R19_T3.2050.92
217_P224_E3.1000.90
12_G16_D3.0960.90
365_N414_N3.0920.90
14_P21_S3.0700.90
16_D21_S2.8930.86
206_I246_F2.8400.85
365_N393_N2.7150.83
181_C204_C2.4300.75
74_I95_F2.4260.75
102_N141_N2.3810.73
435_N464_N2.3800.73
414_N435_N2.3690.73
15_R18_K2.3460.72
76_M107_G2.3140.71
159_V178_I2.2890.70
451_V474_I2.1800.66
76_M156_G2.1720.66
351_G379_G2.1630.65
16_D19_T2.1460.65
219_F224_E2.0760.62
13_V21_S2.0760.62
191_I201_V2.0750.62
140_S174_E2.0670.62
14_P19_T2.0280.60
18_K21_S2.0030.59
117_H188_R1.9790.58
283_I321_N1.9690.58
242_R265_E1.9580.57
13_V17_G1.9580.57
509_D512_I1.9580.57
26_N195_G1.9560.57
192_S224_E1.9340.56
390_F420_S1.8670.54
76_M80_C1.8410.53
189_N219_F1.8270.52
144_I180_R1.8100.51
316_A401_G1.8080.51
152_F186_S1.8070.51
117_H224_E1.8000.51
183_V206_I1.7920.50
139_C142_V1.7780.50
43_P91_G1.7750.50
435_N487_N1.7690.50
10_D20_D1.7290.48
11_F21_S1.7250.48
112_G141_N1.6980.47
466_F474_I1.6720.45
361_K507_I1.6650.45
219_F222_D1.6640.45
484_I524_I1.6200.43
380_L394_C1.6190.43
113_E131_G1.5990.42
15_R20_D1.5900.42
252_S341_N1.5890.42
25_I494_L1.5740.41
258_N264_I1.5730.41
318_I342_N1.5700.41
74_I244_N1.5660.41
393_N414_N1.5640.41
97_V103_I1.5640.41
385_S390_F1.5620.41
107_G241_I1.5620.41
466_F489_L1.5590.41
338_L402_V1.5560.41
262_I341_N1.5560.41
192_S222_D1.5350.40
134_I183_V1.5340.40
342_N414_N1.5310.40
107_G146_D1.5220.39
133_G195_G1.5180.39
12_G21_S1.5090.39
131_G224_E1.4990.38
131_G187_R1.4910.38
17_G47_Y1.4810.38
187_R192_S1.4790.38
187_R222_D1.4730.37
221_I283_I1.4710.37
283_I302_I1.4570.37
21_S41_W1.4540.37
18_K24_R1.4530.37
189_N218_K1.4410.36
221_I224_E1.4270.36
365_N435_N1.4250.36
241_I351_G1.4210.35
12_G24_R1.4170.35
127_T154_G1.4160.35
26_N31_T1.4060.35
117_H131_G1.3940.34
188_R192_S1.3810.34
380_L401_G1.3750.34
285_G386_D1.3680.33
12_G45_G1.3670.33
43_P80_C1.3620.33
107_G262_I1.3610.33
367_I395_L1.3610.33
154_G187_R1.3600.33
422_G449_Y1.3580.33
83_K503_G1.3570.33
402_V422_G1.3530.33
529_S532_S1.3530.33
17_G46_T1.3500.33
176_I486_G1.3460.33
318_I365_N1.3400.32
241_I407_G1.3360.32
29_L464_N1.3290.32
80_C142_V1.3240.32
190_N209_A1.3220.32
188_R224_E1.3210.32
203_E431_V1.3170.32
437_L501_S1.2970.31
82_M108_G1.2970.31
266_G285_G1.2930.31
318_I323_I1.2860.30
157_I183_V1.2860.30
43_P77_D1.2760.30
286_N342_N1.2730.30
13_V18_K1.2700.30
180_R203_E1.2640.30
406_G465_T1.2570.29
161_P285_G1.2520.29
113_E187_R1.2510.29
189_N194_T1.2490.29
321_N365_N1.2420.29
393_N487_N1.2420.29
377_S507_I1.2400.29
190_N194_T1.2340.29
416_L451_V1.2310.29
203_E478_T1.2300.29
178_I204_C1.2290.28
173_S178_I1.2210.28
13_V16_D1.2210.28
318_I411_I1.2190.28
129_E154_G1.2150.28
103_I113_E1.2150.28
11_F31_T1.2140.28
342_N411_I1.2140.28
496_V515_N1.2110.28
241_I259_G1.2100.28
110_I157_I1.2090.28
155_D188_R1.1940.27
154_G195_G1.1870.27
419_F428_G1.1860.27
204_C408_N1.1850.27
179_R202_E1.1760.27
197_D237_I1.1750.27
438_N484_I1.1730.27
13_V20_D1.1630.26
153_T187_R1.1620.26
113_E117_H1.1610.26
133_G152_F1.1520.26
21_S31_T1.1500.26
409_M428_G1.1500.26
461_I484_I1.1490.26
133_G249_N1.1430.26
188_R222_D1.1430.26
487_N510_N1.1420.26
68_V318_I1.1390.26
220_G325_G1.1350.25
142_V199_V1.1330.25
302_I325_G1.1300.25
15_R108_G1.1250.25
203_E509_D1.1250.25
136_I176_I1.1230.25
398_V484_I1.1200.25
176_I243_N1.1190.25
24_R37_Y1.1110.25
129_E222_D1.1070.25
108_G187_R1.1060.24
342_N362_V1.1050.24
144_I157_I1.0890.24
533_I536_G1.0840.24
87_N92_Y1.0770.24
26_N37_Y1.0760.24
430_A476_C1.0750.24
71_N419_F1.0730.23
131_G188_R1.0720.23
246_F321_N1.0670.23
402_V461_I1.0670.23
243_N266_G1.0640.23
125_R266_G1.0630.23
190_N226_Y1.0610.23
17_G45_G1.0590.23
136_I239_V1.0550.23
115_D390_F1.0530.23
202_E242_R1.0490.23
11_F15_R1.0480.23
69_P269_S1.0470.23
185_R208_D1.0430.23
39_T75_M1.0410.23
208_D324_T1.0390.22
189_N192_S1.0370.22
148_K182_E1.0330.22
330_I434_G1.0330.22
132_F154_G1.0300.22
201_V385_S1.0290.22
318_I466_F1.0260.22
110_I134_I1.0250.22
245_H344_I1.0230.22
46_T437_L1.0190.22
473_P516_R1.0190.22
29_L47_Y1.0180.22
136_I139_C1.0170.22
223_I244_N1.0170.22
198_M238_N1.0150.22
239_V336_S1.0140.22
381_R462_K1.0130.22
76_M89_S1.0100.22
129_E187_R1.0100.22
343_K413_D1.0090.22
320_G362_V1.0090.22
523_V534_I1.0030.21
264_I338_L1.0000.21
525_Y535_S0.9970.21
528_G534_I0.9940.21
76_M105_I0.9930.21
266_G382_A0.9920.21
159_V173_S0.9910.21
376_R390_F0.9900.21
399_V405_S0.9890.21
178_I331_D0.9880.21
304_G423_I0.9760.21
514_V527_N0.9750.21
48_L85_I0.9700.21
99_K315_D0.9660.20
482_T487_N0.9650.20
186_S196_C0.9640.20
141_N243_N0.9640.20
25_I261_G0.9630.20
339_V346_N0.9620.20
26_N66_I0.9590.20
144_I249_N0.9580.20
219_F223_I0.9570.20
364_G479_S0.9560.20
14_P239_V0.9560.20
142_V391_L0.9510.20
21_S37_Y0.9490.20
391_L474_I0.9480.20
149_I183_V0.9430.20
21_S38_H0.9390.20
158_I176_I0.9370.20
243_N404_V0.9370.20
41_W75_M0.9340.20
278_G334_G0.9330.20
25_I436_T0.9320.20
188_R219_F0.9310.19
129_E188_R0.9310.19
70_G344_I0.9290.19
11_F82_M0.9290.19
221_I241_I0.9250.19
308_S312_E0.9250.19
117_H217_P0.9240.19
437_L458_G0.9200.19
86_P145_D0.9160.19
117_H129_E0.9160.19
47_Y147_V0.9130.19
101_E528_G0.9120.19
105_I253_S0.9120.19
108_G112_G0.9120.19
283_I291_P0.9090.19
267_N321_N0.9070.19
507_I531_G0.9060.19
451_V469_F0.9060.19
113_E154_G0.9050.19
14_P17_G0.9020.19
320_G404_V0.9010.19
248_G318_I0.8990.19
82_M348_E0.8990.19
66_I223_I0.8970.19
82_M221_I0.8960.19
344_I396_I0.8960.19
19_T42_F0.8940.19
70_G108_G0.8930.19
102_N107_G0.8910.18
27_Q31_T0.8900.18
201_V390_F0.8900.18
243_N264_I0.8880.18
73_E106_S0.8860.18
25_I291_P0.8860.18
206_I259_G0.8860.18
531_G535_S0.8850.18
73_E201_V0.8850.18
99_K317_V0.8820.18
458_G489_L0.8780.18
68_V420_S0.8780.18
15_R38_H0.8760.18
17_G28_C0.8750.18
265_E284_K0.8740.18
159_V401_G0.8730.18
203_E318_I0.8710.18
43_P70_G0.8650.18
522_I528_G0.8630.18
360_V407_G0.8630.18
112_G133_G0.8600.18
131_G192_S0.8600.18
416_L478_T0.8580.18
514_V523_V0.8580.18
437_L489_L0.8550.18
175_Q198_M0.8540.18
178_I285_G0.8540.18
30_S142_V0.8520.18
74_I317_V0.8500.17
27_Q481_K0.8480.17
48_L86_P0.8450.17
80_C105_I0.8440.17
159_V465_T0.8420.17
43_P142_V0.8420.17
66_I266_G0.8420.17
321_N393_N0.8410.17
367_I379_G0.8410.17
464_N482_T0.8400.17
29_L38_H0.8400.17
147_V181_C0.8350.17
318_I321_N0.8330.17
119_Y266_G0.8320.17
68_V201_V0.8250.17
142_V239_V0.8200.17
180_R186_S0.8150.17
189_N209_A0.8140.17
192_S258_N0.8130.17
401_G470_K0.8130.17
474_I479_S0.8110.17
261_G453_V0.8080.16
314_S436_T0.8070.16
463_N491_R0.8060.16
117_H187_R0.8030.16
393_N486_G0.8020.16
178_I200_T0.8010.16
86_P105_I0.7990.16
146_D180_R0.7980.16
108_G189_N0.7970.16
193_I198_M0.7970.16
264_I393_N0.7960.16
26_N267_N0.7960.16
201_V508_F0.7950.16
352_I523_V0.7940.16
456_N460_I0.7940.16
201_V331_D0.7910.16
222_D259_G0.7900.16
522_I525_Y0.7880.16
174_E447_E0.7840.16
191_I196_C0.7820.16
532_S535_S0.7810.16
20_D24_R0.7800.16
264_I271_N0.7790.16
102_N267_N0.7780.16
154_G286_N0.7780.16
74_I258_N0.7780.16
133_G154_G0.7750.16
264_I321_N0.7740.16
140_S283_I0.7730.16
40_V43_P0.7700.16
271_N318_I0.7670.16
329_G365_N0.7640.15
17_G283_I0.7620.15
411_I437_L0.7610.15
422_G474_I0.7590.15
345_S432_I0.7580.15
101_E140_S0.7560.15
66_I108_G0.7540.15
344_I367_I0.7530.15
183_V318_I0.7520.15
201_V281_T0.7520.15
332_V410_I0.7500.15
437_L466_F0.7490.15
280_Q469_F0.7470.15
85_I112_G0.7460.15
393_N435_N0.7420.15
410_I413_D0.7410.15
97_V142_V0.7390.15
423_I464_N0.7350.15
199_V239_V0.7350.15
49_I302_I0.7350.15
83_K249_N0.7320.15
92_Y224_E0.7310.15
81_I282_V0.7300.15
102_N379_G0.7290.15
346_N369_N0.7240.15
159_V206_I0.7230.15
455_N479_S0.7220.15
203_E285_G0.7220.15
390_F477_S0.7210.15
224_E321_N0.7210.15
28_C134_I0.7190.15
24_R28_C0.7190.15
87_N129_E0.7180.15
140_S452_S0.7180.15
330_I486_G0.7170.14
66_I174_E0.7160.14
189_N217_P0.7140.14
262_I320_G0.7120.14
380_L433_E0.7120.14
12_G220_G0.7110.14
156_G206_I0.7110.14
407_G454_T0.7090.14
42_F535_S0.7090.14
515_N521_P0.7090.14
455_N476_C0.7080.14
12_G18_K0.7070.14
107_G266_G0.7070.14
19_T159_V0.7060.14
50_D315_D0.7060.14
144_I388_I0.7050.14
92_Y188_R0.7040.14
403_N434_G0.7040.14
154_G188_R0.7030.14
109_Q149_I0.7020.14
278_G330_I0.7020.14
180_R242_R0.7020.14
265_E269_S0.7020.14
474_I487_N0.7010.14
413_D473_P0.7010.14
103_I177_I0.7000.14
42_F72_L0.6980.14
151_D245_H0.6970.14
503_G507_I0.6960.14
263_L489_L0.6940.14
157_I178_I0.6930.14
49_I246_F0.6930.14
31_T37_Y0.6900.14
77_D80_C0.6880.14
153_T188_R0.6880.14
117_H192_S0.6860.14
149_I157_I0.6850.14
470_K476_C0.6830.14
20_D364_G0.6820.14
529_S536_G0.6810.14
239_V425_I0.6800.14
192_S236_P0.6770.14
92_Y119_Y0.6740.14
133_G259_G0.6740.14
29_L134_I0.6740.14
108_G138_G0.6720.14
88_S113_E0.6710.14
145_D180_R0.6710.14
72_L76_M0.6710.14
49_I321_N0.6700.14
521_P534_I0.6700.14
13_V37_Y0.6690.14
453_V474_I0.6690.14
282_V498_I0.6680.14
434_G469_F0.6670.13
364_G492_S0.6670.13
422_G446_P0.6660.13
21_S66_I0.6660.13
26_N69_P0.6660.13
150_S239_V0.6660.13
21_S118_T0.6660.13
421_R493_P0.6640.13
528_G533_I0.6630.13
149_I259_G0.6620.13
11_F18_K0.6600.13
20_D344_I0.6600.13
114_R188_R0.6590.13
144_I483_S0.6560.13
418_K433_E0.6550.13
431_V509_D0.6540.13
411_I434_G0.6530.13
113_E192_S0.6530.13
15_R453_V0.6520.13
428_G450_S0.6510.13
95_F283_I0.6510.13
243_N483_S0.6510.13
190_N236_P0.6510.13
30_S66_I0.6500.13
156_G159_V0.6500.13
81_I438_N0.6490.13
380_L450_S0.6480.13
188_R194_T0.6480.13
80_C108_G0.6480.13
11_F109_Q0.6480.13
193_I239_V0.6480.13
342_N435_N0.6460.13
46_T134_I0.6450.13
454_T480_A0.6440.13
178_I448_S0.6440.13
343_K401_G0.6440.13
14_P24_R0.6430.13
204_C345_S0.6420.13
345_S366_Q0.6410.13
83_K335_K0.6410.13
370_G410_I0.6410.13
417_R488_H0.6390.13
482_T527_N0.6380.13
502_A512_I0.6370.13
523_V536_G0.6370.13
82_M454_T0.6350.13
134_I401_G0.6350.13
70_G199_V0.6350.13
483_S486_G0.6340.13
493_P496_V0.6340.13
105_I108_G0.6330.13
411_I461_I0.6320.13
39_T74_I0.6310.13
119_Y129_E0.6310.13
359_D426_A0.6310.13
70_G390_F0.6300.13
114_R320_G0.6280.13
265_E428_G0.6280.13
343_K364_G0.6270.13
176_I207_E0.6260.13
51_A326_F0.6250.13
429_N468_E0.6240.13
341_N499_Y0.6230.13
522_I530_A0.6230.13
42_F159_V0.6220.13
87_N131_G0.6220.13
196_C225_G0.6210.13
354_V446_P0.6190.13
105_I209_A0.6190.13
95_F147_V0.6170.13
17_G21_S0.6160.13
16_D525_Y0.6150.13
40_V399_V0.6140.12
151_D278_G0.6140.12
322_L343_K0.6130.12
159_V466_F0.6120.12
113_E224_E0.6110.12
264_I386_D0.6110.12
289_R324_T0.6100.12
114_R117_H0.6090.12
49_I195_G0.6080.12
197_D269_S0.6060.12
92_Y117_H0.6060.12
76_M189_N0.6060.12
21_S131_G0.6060.12
113_E186_S0.6050.12
304_G413_D0.6050.12
110_I248_G0.6050.12
50_D134_I0.6040.12
261_G495_L0.6020.12
13_V119_Y0.6010.12
95_F244_N0.6000.12
367_I435_N0.6000.12
112_G334_G0.6000.12
182_E207_E0.6000.12
222_D225_G0.5990.12
23_E486_G0.5990.12
44_K79_E0.5990.12
29_L147_V0.5980.12
132_F188_R0.5980.12
117_H154_G0.5970.12
510_N514_V0.5970.12
179_R362_V0.5960.12
176_I436_T0.5960.12
72_L481_K0.5950.12
241_I286_N0.5940.12
411_I433_E0.5930.12
71_N477_S0.5920.12
364_G473_P0.5910.12
323_I404_V0.5910.12
209_A222_D0.5900.12
49_I84_V0.5900.12
512_I531_G0.5860.12
117_H127_T0.5850.12
524_I527_N0.5850.12
437_L474_I0.5850.12
423_I432_I0.5840.12
222_D258_N0.5840.12
128_H249_N0.5840.12
454_T504_V0.5820.12
451_V465_T0.5810.12
380_L402_V0.5800.12
488_H496_V0.5800.12
101_E328_T0.5790.12
110_I149_I0.5790.12
409_M489_L0.5790.12
131_G217_P0.5760.12
263_L343_K0.5750.12
416_L437_L0.5750.12
76_M131_G0.5730.12
22_T334_G0.5730.12
362_V415_L0.5720.12
527_N535_S0.5720.12
156_G194_T0.5720.12
92_Y222_D0.5710.12
415_L471_N0.5700.12
103_I198_M0.5690.12
352_I522_I0.5680.12
329_G367_I0.5680.12
145_D179_R0.5680.12
180_R416_L0.5670.12
11_F24_R0.5660.12
102_N334_G0.5660.12
46_T287_I0.5660.12
458_G470_K0.5650.12
181_C286_N0.5650.12
258_N414_N0.5640.12
184_R207_E0.5610.12
419_F450_S0.5610.12
392_N481_K0.5600.12
185_R320_G0.5600.12
249_N252_S0.5580.11
293_D302_I0.5580.11
41_W73_E0.5570.11
69_P79_E0.5570.11
220_G269_S0.5560.11
218_K222_D0.5540.11
365_N400_D0.5530.11
92_Y187_R0.5500.11
330_I475_Y0.5480.11
21_S114_R0.5480.11
117_H195_G0.5470.11
237_I351_G0.5460.11
318_I418_K0.5460.11
421_R426_A0.5460.11
49_I313_T0.5430.11
79_E206_I0.5430.11
17_G24_R0.5430.11
510_N513_S0.5430.11
113_E133_G0.5420.11
204_C223_I0.5420.11
92_Y129_E0.5420.11
66_I310_G0.5400.11
424_W480_A0.5390.11
49_I315_D0.5380.11
411_I430_A0.5380.11
503_G512_I0.5380.11
42_F81_I0.5380.11
402_V492_S0.5370.11
507_I512_I0.5370.11
283_I286_N0.5370.11
402_V435_N0.5370.11
25_I67_I0.5360.11
423_I455_N0.5360.11
113_E119_Y0.5350.11
13_V42_F0.5350.11
182_E271_N0.5340.11
42_F50_D0.5340.11
113_E127_T0.5330.11
29_L82_M0.5330.11
422_G431_V0.5320.11
424_W439_P0.5310.11
200_T282_V0.5310.11
119_Y128_H0.5300.11
178_I191_I0.5300.11
148_K191_I0.5300.11
97_V411_I0.5280.11
246_F269_S0.5280.11
117_H136_I0.5260.11
138_G156_G0.5260.11
474_I491_R0.5260.11
274_S304_G0.5260.11
425_I493_P0.5220.11
42_F71_N0.5210.11
178_I362_V0.5190.11
302_I329_G0.5190.11
395_L411_I0.5180.11
48_L118_T0.5180.11
15_R467_K0.5180.11
84_V189_N0.5160.11
10_D15_R0.5160.11
108_G135_C0.5150.11
26_N38_H0.5150.11
72_L138_G0.5150.11
132_F201_V0.5150.11
268_H396_I0.5140.11
385_S393_N0.5140.11
308_S311_K0.5130.11
404_V415_L0.5130.11
87_N267_N0.5130.11
84_V209_A0.5120.11
206_I526_L0.5120.11
466_F502_A0.5110.11
338_L533_I0.5100.11
83_K114_R0.5100.11
99_K405_S0.5100.11
511_T524_I0.5080.11
244_N408_N0.5080.11
127_T130_W0.5070.11
255_T344_I0.5070.11
523_V527_N0.5070.11
451_V515_N0.5070.11
452_S528_G0.5060.11
238_N344_I0.5060.11
71_N198_M0.5050.11
417_R493_P0.5040.11
315_D362_V0.5020.11
509_D521_P0.5020.11
386_D416_L0.5010.11
156_G183_V0.5010.11
154_G225_G0.5010.11
320_G466_F0.5000.11
419_F452_S0.5000.11
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3gq8A 3 0.8818 100 0.622 Contact Map
2uvfA 2 0.5976 100 0.623 Contact Map
3sucA 3 0.8921 100 0.629 Contact Map
3jurA 3 0.589 100 0.631 Contact Map
2pygA 1 0.5925 100 0.643 Contact Map
4mr0A 1 0.6832 100 0.647 Contact Map
4mxnA 1 0.363 100 0.674 Contact Map
1bheA 1 0.536 100 0.687 Contact Map
1rmgA 1 0.6438 100 0.687 Contact Map
2x6wA 3 0.8339 100 0.689 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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