GREMLIN Database
BSDB - Phenolic acid decarboxylase subunit B
UniProt: P94404 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 204 (184)
Sequences: 1872 (1238)
Seq/√Len: 91.2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
143_E150_K3.2651.00
139_Q149_T3.1511.00
143_E147_A2.9791.00
102_L145_M2.9751.00
148_L153_T2.9031.00
14_K41_E2.7721.00
30_R174_D2.6271.00
139_Q146_L2.6261.00
139_Q150_K2.3731.00
30_R33_Q2.3701.00
18_G114_L2.3461.00
178_F191_A2.2961.00
182_D193_R2.2571.00
103_A109_M2.1911.00
95_A131_L2.1551.00
43_H73_Y2.1421.00
45_V82_I2.1301.00
19_M28_G2.0991.00
20_T114_L2.0251.00
142_L146_L2.0171.00
93_I180_T1.9691.00
99_M132_T1.9261.00
49_W78_Q1.8271.00
73_Y81_A1.8111.00
137_L159_M1.7711.00
31_L93_I1.7311.00
125_R149_T1.6551.00
169_L172_M1.6281.00
92_M121_M1.6161.00
47_S114_L1.6151.00
88_D187_R1.5671.00
139_Q151_M1.5381.00
97_C102_L1.5211.00
122_L153_T1.5161.00
170_E174_D1.5141.00
104_S109_M1.5041.00
146_L150_K1.4851.00
95_A180_T1.4801.00
89_T121_M1.4751.00
17_V32_L1.4711.00
102_L148_L1.4671.00
131_L180_T1.4500.99
179_R191_A1.4290.99
148_L155_I1.4260.99
25_A54_I1.4070.99
125_R154_I1.4020.99
143_E146_L1.3950.99
48_P76_K1.3860.99
75_H112_N1.3750.99
15_L184_F1.3720.99
59_G165_R1.3630.99
129_V184_F1.3620.99
167_R171_E1.3430.99
108_G144_N1.3290.99
91_G184_F1.3120.99
28_G95_A1.2760.99
154_I183_Q1.2690.99
119_D141_H1.2670.99
31_L95_A1.2160.98
103_A107_T1.2030.98
54_I58_T1.1970.98
43_H87_F1.1970.98
103_A144_N1.1920.98
100_K109_M1.1880.98
105_I118_A1.1870.98
110_A119_D1.1710.98
156_L176_I1.1680.98
31_L177_V1.1650.98
16_V121_M1.1630.98
94_V105_I1.1590.97
13_V90_D1.1560.97
48_P75_H1.1550.97
162_F173_V1.1480.97
88_D185_G1.1410.97
131_L176_I1.1360.97
17_V95_A1.1340.97
27_F160_P1.1320.97
93_I184_F1.1250.97
36_K70_T1.1170.97
140_I144_N1.1100.97
16_V89_T1.1030.97
140_I151_M1.1030.97
178_F188_L1.0970.96
17_V42_T1.0960.96
104_S111_D1.0910.96
127_K183_Q1.0870.96
108_G140_I1.0840.96
132_T156_L1.0760.96
131_L158_P1.0720.96
27_F158_P1.0720.96
100_K115_T1.0670.96
32_L42_T1.0560.96
135_T156_L1.0350.95
122_L151_M1.0310.95
92_M117_A1.0290.95
99_M144_N1.0280.95
148_L151_M1.0210.95
16_V82_I1.0110.94
34_W190_E1.0040.94
48_P51_N1.0020.94
122_L138_N0.9960.94
100_K104_S0.9930.94
161_A175_H0.9790.93
14_K90_D0.9690.93
34_W37_A0.9650.93
51_N66_E0.9600.93
127_K185_G0.9480.92
135_T176_I0.9450.92
73_Y77_D0.9430.92
99_M103_A0.9420.92
31_L180_T0.9350.92
94_V118_A0.9300.92
149_T153_T0.9290.92
30_R170_E0.9270.91
29_V54_I0.9260.91
26_I173_V0.9240.91
92_M118_A0.9140.91
111_D115_T0.9060.90
44_L69_A0.9060.90
99_M141_H0.8820.89
104_S115_T0.8810.89
156_L180_T0.8730.89
40_V186_I0.8690.89
19_M50_A0.8630.88
55_K61_T0.8570.88
131_L156_L0.8530.88
156_L179_R0.8530.88
85_G123_K0.8520.88
27_F176_I0.8520.88
166_P171_E0.8510.88
121_M128_L0.8500.87
102_L144_N0.8430.87
158_P176_I0.8360.87
52_V78_Q0.8350.87
79_A83_S0.8290.86
139_Q153_T0.8290.86
149_T155_I0.8270.86
56_H79_A0.8230.86
147_A151_M0.8210.86
29_V58_T0.8200.86
18_G92_M0.8160.85
129_V183_Q0.8150.85
64_E67_Q0.8150.85
32_L44_L0.8130.85
138_N144_N0.8040.84
65_V69_A0.8030.84
130_L148_L0.8020.84
52_V55_K0.8020.84
83_S113_L0.8020.84
19_M25_A0.7990.84
85_G124_E0.7980.84
144_N148_L0.7930.84
85_G120_V0.7890.83
100_K119_D0.7880.83
46_V50_A0.7810.83
105_I130_L0.7750.82
53_T100_K0.7750.82
40_V90_D0.7720.82
106_R147_A0.7640.81
110_A115_T0.7640.81
117_A121_M0.7620.81
48_P52_V0.7620.81
112_N115_T0.7560.81
52_V56_H0.7540.80
15_L40_V0.7500.80
88_D126_K0.7460.80
92_M128_L0.7410.79
175_H191_A0.7380.79
107_T144_N0.7380.79
142_L148_L0.7360.79
23_T49_W0.7360.79
147_A150_K0.7350.79
97_C130_L0.7340.79
156_L183_Q0.7320.78
132_T159_M0.7300.78
94_V130_L0.7240.78
120_V123_K0.7240.78
109_M112_N0.7190.77
34_W177_V0.7140.77
38_A186_I0.7140.77
121_M126_K0.6860.74
34_W174_D0.6860.74
44_L72_T0.6820.73
132_T137_L0.6750.73
41_E87_F0.6740.72
30_R177_V0.6700.72
179_R183_Q0.6680.72
158_P175_H0.6630.71
52_V79_A0.6630.71
63_Q66_E0.6620.71
93_I129_V0.6620.71
16_V92_M0.6620.71
46_V72_T0.6600.71
120_V124_E0.6600.71
106_R148_L0.6530.70
60_Y64_E0.6500.70
76_K79_A0.6470.69
27_F173_V0.6430.69
100_K110_A0.6400.69
139_Q148_L0.6380.68
13_V39_G0.6370.68
104_S112_N0.6370.68
103_A106_R0.6310.67
14_K88_D0.6290.67
15_L91_G0.6260.67
25_A28_G0.6230.67
168_S171_E0.6220.66
132_T142_L0.6190.66
174_D177_V0.6180.66
29_V33_Q0.6160.66
34_W188_L0.6150.66
16_V45_V0.6130.65
66_E70_T0.6120.65
160_P172_M0.6110.65
110_A138_N0.6060.64
19_M46_V0.6060.64
98_S159_M0.5950.63
51_N75_H0.5910.62
46_V62_L0.5870.62
46_V54_I0.5870.62
20_T98_S0.5830.61
123_K141_H0.5800.61
125_R183_Q0.5790.61
104_S141_H0.5780.61
118_A128_L0.5780.61
188_L193_R0.5770.61
65_V70_T0.5760.60
81_A195_N0.5740.60
91_G126_K0.5730.60
60_Y65_V0.5730.60
129_V180_T0.5720.60
81_A196_G0.5720.60
25_A50_A0.5710.60
160_P179_R0.5710.60
119_D138_N0.5700.60
27_F162_F0.5690.60
108_G138_N0.5690.60
62_L66_E0.5670.59
14_K43_H0.5660.59
31_L181_L0.5650.59
69_A72_T0.5640.59
78_Q83_S0.5570.58
16_V117_A0.5560.58
33_Q60_Y0.5560.58
87_F91_G0.5500.57
30_R173_V0.5450.56
66_E72_T0.5440.56
42_T69_A0.5430.56
97_C101_S0.5390.55
46_V49_W0.5370.55
65_V68_L0.5340.55
45_V79_A0.5320.55
29_V65_V0.5300.54
146_L149_T0.5280.54
171_E174_D0.5280.54
166_P169_L0.5270.54
41_E90_D0.5260.54
79_A98_S0.5260.54
76_K167_R0.5240.53
93_I181_L0.5230.53
41_E71_Y0.5220.53
71_Y81_A0.5210.53
46_V65_V0.5200.53
137_L145_M0.5200.53
135_T157_P0.5190.53
88_D193_R0.5190.53
99_M119_D0.5150.52
15_L186_I0.5130.52
89_T126_K0.5130.52
19_M32_L0.5130.52
32_L39_G0.5110.52
51_N62_L0.5100.51
97_C145_M0.5080.51
127_K154_I0.5060.51
50_A56_H0.5040.51
55_K58_T0.5000.50
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4rhfA 6 0.9118 100 0.353 Contact Map
4zavA 6 0.951 100 0.354 Contact Map
2ejbA 6 0.8431 100 0.364 Contact Map
1sbzA 6 0.9069 100 0.364 Contact Map
3lqkA 5 0.9118 100 0.504 Contact Map
3mcuA 5 0.8578 100 0.532 Contact Map
1g63A 6 0.7549 100 0.541 Contact Map
1qzuA 3 0.7059 100 0.544 Contact Map
1p3y1 6 0.8039 100 0.56 Contact Map
3wisA 4 0.7843 100 0.57 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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