YCGH - BACSU - GREMLIN Contacts

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YCGH - Uncharacterized transporter YcgH

UniProt:	P94383	Sequences: MSQTKKDQPKGNLAWWQLSLIGVGCTIGTGFFLGSSIAIVKSGFSVLLSFLIAGIGTYFVFEQLAKLSAKQPEKGSFCAYARKAFGKWAGFSNGWVYWTSEMLITGSQLTAISLFTKHWFPQVPLWVFASIYAVLGLLIIFTGLSVFEKTENVLAVIKTAAIFMFIVIAILALCGILSGGNHGIHVPNKTSEFFPYGAMGLWTGLIYAFYAFGGIEVMGLMAVHLKKPEEASKSGKLMLATLAIIYIISIGLALLLVPLHTFTEQDSPFITSLKGYNLEIILDIFNGIFIIAGFSTLVASLFAVTTLLCTMADDGDAPKCFTLKEGKKICWPALGLTFAGLVLSIILSLVLPKNIYEHMTTAAGLMLLYTWLFILFSSKKLTDPEGMGKTQIYLAMVLIAAAVSGTLFEKSSRPGFFVSIGFLVIIAIVTMIYQKKQGHKDRPASP	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	446 (416)
Sequences:	24830 (16256)
Seq/√Len:	797.0

ECOLI - YIFK PROY AROP PUUP GABP ANSP PLAP POTE PHEP LYSP FRLA ADIC MMUP CYCA YBAT CADB ARCD GADC YJEH YCAM YJEM YGJI
BACSU - YCGH YTNA YBXG ROCC GABP HUTM YBGF YVBW AAPA YDGF YHDG ASPP ROCE YBEC YFNA STET ARCD YECA YDAO GERBB GERAB YNDE GERKB YFKT
HALSA - Q9HHU7 Q9HQB3 Q9HSL5
SULSO - Q97U05 Q97XM0 Q7LXI7 Q97ZB5 Q97VR4 Q97X49 Q97WS3 Q97U33 Q97WD4 Q97Z63 Q97Y76 Q97VA8 Q97VA6 Q97YN3 Q97YX9 Q97U39

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
137_L	338_F	4.367	1.00
320_C	332_P	4.359	1.00
54_G	243_A	3.257	1.00
323_L	332_P	3.125	1.00
230_E	233_K	2.949	1.00
14_A	226_K	2.922	1.00
94_G	311_M	2.742	1.00
78_C	314_D	2.735	1.00
225_L	231_A	2.699	1.00
312_A	322_T	2.645	1.00
325_E	331_W	2.641	1.00
169_A	252_L	2.596	1.00
130_S	342_V	2.497	1.00
19_S	237_L	2.467	1.00
320_C	323_L	2.450	1.00
227_K	230_E	2.414	1.00
167_V	171_L	2.408	1.00
15_W	237_L	2.405	1.00
223_V	313_D	2.366	1.00
280_I	284_I	2.362	1.00
393_Y	397_V	2.356	1.00
82_R	90_G	2.282	1.00
224_H	306_T	2.202	1.00
18_L	225_L	2.180	1.00
335_G	339_A	2.172	1.00
138_L	142_T	2.143	1.00
309_C	313_D	2.118	1.00
15_W	19_S	2.095	1.00
145_S	149_K	2.094	1.00
134_V	342_V	2.094	1.00
15_W	231_A	2.087	1.00
141_F	331_W	2.082	1.00
66_K	382_T	2.079	1.00
137_L	334_L	2.052	1.00
85_F	380_K	2.038	1.00
233_K	237_L	2.007	1.00
129_A	345_I	1.997	1.00
14_A	17_Q	1.982	1.00
82_R	87_K	1.981	1.00
130_S	345_I	1.979	1.00
395_A	399_I	1.966	1.00
271_T	274_K	1.966	1.00
63_Q	375_L	1.958	1.00
398_L	402_A	1.944	1.00
261_T	275_G	1.930	1.00
9_P	324_K	1.926	1.00
315_G	319_K	1.914	1.00
98_W	337_T	1.912	1.00
428_I	432_I	1.902	1.00
156_V	160_A	1.879	1.00
321_F	336_L	1.864	1.00
426_I	429_V	1.860	1.00
55_I	59_F	1.855	1.00
258_P	261_T	1.840	1.00
38_A	46_V	1.839	1.00
394_L	398_L	1.838	1.00
383_D	386_G	1.829	1.00
85_F	376_F	1.826	1.00
397_V	401_A	1.805	1.00
271_T	275_G	1.787	1.00
372_L	401_A	1.771	1.00
17_Q	152_N	1.749	1.00
397_V	404_S	1.736	1.00
236_K	240_A	1.735	1.00
134_V	338_F	1.731	1.00
140_I	298_V	1.727	1.00
45_S	201_L	1.709	1.00
427_A	431_M	1.687	1.00
49_S	204_G	1.687	1.00
81_A	93_N	1.683	1.00
325_E	329_I	1.678	1.00
13_L	17_Q	1.668	1.00
105_T	341_L	1.667	1.00
109_L	297_L	1.662	1.00
88_W	430_T	1.662	1.00
404_S	407_L	1.659	1.00
160_A	164_M	1.656	1.00
141_F	335_G	1.653	1.00
133_A	341_L	1.647	1.00
227_K	231_A	1.645	1.00
19_S	241_T	1.627	1.00
93_N	373_F	1.607	1.00
95_W	426_I	1.581	1.00
22_G	238_M	1.566	1.00
240_A	244_I	1.532	1.00
394_L	397_V	1.519	1.00
161_A	288_I	1.516	1.00
183_G	186_V	1.515	1.00
86_G	89_A	1.511	1.00
308_L	333_A	1.511	1.00
116_T	128_F	1.498	1.00
304_V	337_T	1.495	1.00
9_P	309_C	1.482	1.00
402_A	406_T	1.475	1.00
53_A	208_A	1.475	1.00
227_K	233_K	1.475	1.00
124_P	127_V	1.470	1.00
221_M	302_F	1.469	1.00
184_I	187_P	1.466	1.00
109_L	133_A	1.460	1.00
380_K	384_P	1.457	1.00
332_P	336_L	1.453	1.00
375_L	400_A	1.444	1.00
309_C	324_K	1.439	1.00
85_F	89_A	1.431	1.00
137_L	335_G	1.424	1.00
384_P	388_G	1.412	1.00
274_K	282_L	1.409	1.00
319_K	322_T	1.406	1.00
10_K	328_K	1.400	1.00
112_I	290_I	1.397	1.00
228_P	232_S	1.389	1.00
170_I	252_L	1.387	1.00
319_K	323_L	1.379	1.00
74_K	223_V	1.377	1.00
61_F	239_L	1.376	1.00
305_T	334_L	1.369	1.00
133_A	338_F	1.364	1.00
17_Q	148_E	1.361	1.00
71_Q	83_K	1.356	1.00
420_I	424_V	1.352	1.00
81_A	373_F	1.351	1.00
429_V	433_Y	1.351	1.00
283_D	287_G	1.345	1.00
265_Q	271_T	1.345	1.00
112_I	132_Y	1.342	1.00
159_T	163_F	1.340	1.00
130_S	134_V	1.340	1.00
323_L	331_W	1.317	1.00
166_I	248_I	1.313	1.00
26_T	242_L	1.311	1.00
60_V	375_L	1.295	1.00
62_E	236_K	1.286	1.00
417_F	421_G	1.283	1.00
61_F	235_G	1.281	1.00
244_I	248_I	1.281	1.00
380_K	383_D	1.280	1.00
84_A	377_S	1.276	1.00
398_L	401_A	1.276	1.00
413_R	416_F	1.270	1.00
267_S	271_T	1.260	1.00
13_L	148_E	1.256	1.00
15_W	233_K	1.256	1.00
79_A	83_K	1.253	1.00
33_L	111_A	1.237	1.00
376_F	380_K	1.235	1.00
173_L	255_L	1.234	1.00
403_V	407_L	1.233	1.00
108_Q	296_T	1.230	1.00
13_L	18_L	1.229	1.00
409_E	412_S	1.227	1.00
66_K	69_A	1.226	1.00
136_G	297_L	1.224	1.00
45_S	194_F	1.212	1.00
384_P	387_M	1.206	1.00
47_L	251_G	1.205	1.00
169_A	256_L	1.200	1.00
16_W	20_L	1.191	1.00
422_F	426_I	1.184	1.00
308_L	317_A	1.184	1.00
395_A	398_L	1.182	1.00
171_L	176_I	1.181	1.00
165_F	169_A	1.179	1.00
421_G	424_V	1.177	1.00
393_Y	398_L	1.169	1.00
413_R	417_F	1.165	1.00
274_K	279_E	1.156	1.00
64_L	77_F	1.154	1.00
170_I	174_C	1.145	1.00
81_A	89_A	1.142	1.00
98_W	308_L	1.140	1.00
18_L	234_S	1.135	1.00
73_E	79_A	1.131	1.00
91_F	95_W	1.131	1.00
22_G	218_M	1.129	1.00
139_I	150_T	1.124	1.00
88_W	427_A	1.121	1.00
68_S	80_Y	1.120	1.00
150_T	154_L	1.119	1.00
174_C	177_L	1.116	1.00
186_V	189_K	1.116	1.00
393_Y	396_M	1.116	1.00
127_V	131_I	1.107	1.00
395_A	404_S	1.103	1.00
151_E	298_V	1.098	1.00
164_M	168_I	1.092	1.00
12_N	226_K	1.090	1.00
332_P	335_G	1.087	1.00
226_K	231_A	1.081	1.00
400_A	404_S	1.080	1.00
23_V	241_T	1.077	1.00
116_T	290_I	1.076	1.00
339_A	343_L	1.076	1.00
131_I	135_L	1.068	1.00
113_S	128_F	1.063	1.00
123_V	127_V	1.063	1.00
324_K	328_K	1.062	1.00
149_K	153_V	1.061	1.00
21_I	221_M	1.061	1.00
395_A	406_T	1.059	1.00
78_C	310_T	1.057	1.00
137_L	141_F	1.054	1.00
397_V	407_L	1.052	1.00
412_S	415_G	1.050	1.00
258_P	275_G	1.043	1.00
388_G	391_Q	1.040	1.00
163_F	167_V	1.035	1.00
73_E	83_K	1.030	1.00
126_W	130_S	1.024	1.00
313_D	322_T	1.019	1.00
144_L	302_F	1.013	1.00
70_K	388_G	1.011	1.00
141_F	329_I	1.009	1.00
70_K	386_G	1.008	1.00
385_E	388_G	1.007	1.00
383_D	387_M	1.003	1.00
185_H	188_N	1.003	1.00
134_V	138_L	1.003	1.00
400_A	406_T	0.999	1.00
410_K	413_R	0.998	1.00
159_T	245_I	0.994	1.00
116_T	120_F	0.993	1.00
23_V	242_L	0.991	1.00
186_V	190_T	0.985	1.00
389_K	392_I	0.984	1.00
388_G	392_I	0.983	1.00
372_L	376_F	0.983	1.00
51_L	247_I	0.979	1.00
191_S	194_F	0.979	1.00
403_V	406_T	0.972	1.00
414_P	417_F	0.969	1.00
154_L	295_S	0.969	1.00
141_F	325_E	0.965	1.00
379_K	382_T	0.965	1.00
279_E	283_D	0.963	1.00
113_S	129_A	0.962	1.00
39_I	46_V	0.961	1.00
213_G	367_L	0.959	1.00
393_Y	404_S	0.958	1.00
421_G	425_I	0.956	1.00
412_S	416_F	0.953	1.00
54_G	212_F	0.951	1.00
396_M	400_A	0.949	1.00
136_G	298_V	0.949	1.00
47_L	254_L	0.943	1.00
243_A	247_I	0.942	1.00
189_K	192_E	0.941	1.00
398_L	406_T	0.939	1.00
55_I	399_I	0.938	1.00
365_L	419_S	0.930	1.00
216_E	220_L	0.929	1.00
166_I	170_I	0.923	1.00
394_L	403_V	0.921	1.00
424_V	428_I	0.917	1.00
187_P	190_T	0.917	1.00
251_G	255_L	0.916	1.00
88_W	92_S	0.915	1.00
20_L	152_N	0.915	1.00
418_V	421_G	0.913	1.00
9_P	224_H	0.908	1.00
171_L	175_G	0.906	1.00
166_I	252_L	0.901	1.00
158_K	292_A	0.899	1.00
95_W	317_A	0.893	1.00
75_G	78_C	0.891	1.00
411_S	415_G	0.890	1.00
107_S	210_Y	0.888	1.00
9_P	306_T	0.885	1.00
301_L	338_F	0.883	1.00
12_N	145_S	0.883	1.00
75_G	79_A	0.881	1.00
393_Y	400_A	0.880	1.00
401_A	405_G	0.879	1.00
408_F	411_S	0.879	1.00
323_L	326_G	0.878	1.00
416_F	419_S	0.878	1.00
184_I	188_N	0.876	1.00
277_N	281_I	0.876	1.00
414_P	418_V	0.874	1.00
82_R	314_D	0.874	1.00
268_P	273_L	0.869	1.00
27_I	30_G	0.867	1.00
122_Q	125_L	0.865	1.00
135_L	294_F	0.864	1.00
394_L	401_A	0.861	1.00
338_F	342_V	0.858	1.00
128_F	131_I	0.856	1.00
321_F	332_P	0.852	1.00
400_A	403_V	0.850	1.00
317_A	321_F	0.848	1.00
197_G	200_G	0.845	1.00
397_V	400_A	0.844	1.00
183_G	187_P	0.844	1.00
203_T	207_Y	0.844	1.00
430_T	434_Q	0.843	1.00
97_Y	101_E	0.843	1.00
237_L	241_T	0.843	1.00
339_A	342_V	0.842	1.00
194_F	197_G	0.841	1.00
394_L	406_T	0.840	1.00
17_Q	149_K	0.840	1.00
86_G	431_M	0.839	1.00
411_S	416_F	0.839	1.00
59_F	399_I	0.838	1.00
58_Y	62_E	0.835	1.00
89_A	373_F	0.834	1.00
425_I	429_V	0.834	1.00
56_G	403_V	0.833	1.00
398_L	407_L	0.829	1.00
107_S	360_T	0.828	1.00
149_K	152_N	0.827	1.00
393_Y	399_I	0.826	1.00
331_W	335_G	0.826	1.00
16_W	152_N	0.821	1.00
411_S	414_P	0.820	1.00
112_I	293_G	0.819	1.00
217_V	303_A	0.817	1.00
59_F	63_Q	0.816	1.00
417_F	420_I	0.815	1.00
110_T	359_M	0.815	1.00
273_L	278_L	0.814	1.00
184_I	255_L	0.814	1.00
401_A	404_S	0.812	1.00
385_E	391_Q	0.812	1.00
51_L	55_I	0.812	1.00
256_L	272_S	0.811	1.00
194_F	201_L	0.810	1.00
173_L	176_I	0.808	1.00
401_A	406_T	0.806	1.00
138_L	141_F	0.806	1.00
408_F	416_F	0.806	1.00
278_L	281_I	0.801	1.00
408_F	412_S	0.797	1.00
112_I	294_F	0.796	1.00
133_A	345_I	0.796	1.00
63_Q	397_V	0.794	1.00
397_V	406_T	0.794	1.00
58_Y	236_K	0.791	1.00
170_I	248_I	0.788	1.00
171_L	174_C	0.787	1.00
419_S	423_L	0.785	1.00
265_Q	268_P	0.782	1.00
48_L	52_I	0.781	1.00
362_A	366_M	0.780	1.00
190_T	195_P	0.778	1.00
27_I	158_K	0.778	1.00
213_G	371_W	0.777	1.00
378_S	382_T	0.776	1.00
165_F	273_L	0.772	1.00
102_M	340_G	0.768	1.00
228_P	231_A	0.768	1.00
136_G	301_L	0.768	1.00
81_A	377_S	0.768	1.00
198_A	201_L	0.768	1.00
48_L	201_L	0.766	1.00
394_L	399_I	0.765	1.00
267_S	270_I	0.764	1.00
12_N	144_L	0.764	1.00
396_M	404_S	0.758	1.00
67_L	378_S	0.758	1.00
185_H	189_K	0.756	1.00
326_G	331_W	0.754	1.00
387_M	391_Q	0.752	1.00
410_K	414_P	0.749	1.00
142_T	146_V	0.747	1.00
395_A	400_A	0.747	1.00
27_I	245_I	0.745	1.00
402_A	405_G	0.745	1.00
396_M	401_A	0.745	1.00
67_L	80_Y	0.744	1.00
227_K	232_S	0.743	1.00
126_W	345_I	0.742	1.00
31_F	249_S	0.742	1.00
15_W	234_S	0.741	1.00
429_V	432_I	0.734	1.00
78_C	82_R	0.731	1.00
9_P	12_N	0.725	1.00
26_T	238_M	0.724	1.00
431_M	435_K	0.722	1.00
140_I	334_L	0.717	1.00
394_L	400_A	0.716	1.00
16_W	149_K	0.713	1.00
273_L	276_Y	0.712	1.00
85_F	377_S	0.711	1.00
432_I	435_K	0.710	1.00
173_L	252_L	0.710	1.00
123_V	126_W	0.709	1.00
57_T	215_I	0.707	1.00
19_S	234_S	0.707	1.00
393_Y	403_V	0.706	1.00
166_I	249_S	0.702	1.00
104_I	363_A	0.701	1.00
183_G	188_N	0.701	1.00
325_E	328_K	0.700	1.00
305_T	333_A	0.700	1.00
422_F	425_I	0.699	1.00
418_V	422_F	0.698	1.00
241_T	245_I	0.691	1.00
140_I	302_F	0.689	1.00
312_A	321_F	0.688	1.00
382_T	386_G	0.688	1.00
100_S	367_L	0.685	1.00
64_L	374_I	0.685	1.00
101_E	300_S	0.682	1.00
280_I	283_D	0.680	1.00
103_L	362_A	0.680	1.00
393_Y	401_A	0.679	1.00
301_L	305_T	0.675	1.00
423_L	427_A	0.673	1.00
136_G	294_F	0.672	1.00
47_L	51_L	0.671	1.00
252_L	255_L	0.670	1.00
35_S	250_I	0.670	1.00
141_F	334_L	0.668	1.00
113_S	116_T	0.667	1.00
48_L	51_L	0.665	1.00
306_T	309_C	0.665	1.00
249_S	253_A	0.665	1.00
106_G	359_M	0.665	1.00
397_V	403_V	0.663	1.00
24_G	155_A	0.662	1.00
194_F	198_A	0.662	1.00
232_S	235_G	0.661	1.00
46_V	250_I	0.659	1.00
44_F	254_L	0.659	1.00
173_L	177_L	0.658	1.00
28_G	246_Y	0.658	1.00
268_P	272_S	0.658	1.00
394_L	407_L	0.658	1.00
115_F	289_F	0.657	1.00
108_Q	297_L	0.653	1.00
148_E	152_N	0.652	1.00
385_E	390_T	0.652	1.00
122_Q	126_W	0.652	1.00
397_V	402_A	0.651	1.00
394_L	402_A	0.650	1.00
12_N	16_W	0.649	1.00
393_Y	406_T	0.646	1.00
38_A	42_S	0.646	1.00
86_G	90_G	0.646	1.00
130_S	346_I	0.643	1.00
116_T	132_Y	0.642	1.00
106_G	344_S	0.641	1.00
304_V	308_L	0.641	1.00
19_S	22_G	0.639	1.00
50_F	211_A	0.639	1.00
148_E	298_V	0.637	1.00
393_Y	407_L	0.637	1.00
223_V	309_C	0.636	1.00
377_S	381_L	0.635	1.00
134_V	137_L	0.635	1.00
78_C	94_G	0.635	1.00
219_G	235_G	0.634	1.00
47_L	247_I	0.632	1.00
132_Y	297_L	0.631	1.00
118_H	286_N	0.630	1.00
372_L	405_G	0.630	1.00
320_C	336_L	0.630	1.00
396_M	407_L	0.629	1.00
61_F	215_I	0.629	1.00
249_S	269_F	0.628	1.00
52_I	205_L	0.627	1.00
410_K	416_F	0.626	1.00
74_K	309_C	0.626	1.00
385_E	389_K	0.623	1.00
157_I	288_I	0.621	1.00
67_L	84_A	0.621	1.00
37_I	357_E	0.619	1.00
117_K	125_L	0.619	1.00
428_I	431_M	0.619	1.00
66_K	70_K	0.618	1.00
25_C	299_A	0.618	1.00
168_I	172_A	0.617	1.00
34_G	360_T	0.616	1.00
96_V	370_T	0.616	1.00
65_A	69_A	0.615	1.00
308_L	336_L	0.614	1.00
25_C	300_S	0.613	1.00
84_A	381_L	0.613	1.00
357_E	360_T	0.611	1.00
422_F	429_V	0.610	1.00
189_K	193_F	0.609	1.00
224_H	330_C	0.609	1.00
146_V	149_K	0.608	1.00
366_M	370_T	0.608	1.00
16_W	19_S	0.606	1.00
146_V	150_T	0.604	1.00
241_T	244_I	0.603	1.00
104_I	107_S	0.600	1.00
68_S	219_G	0.600	1.00
155_A	158_K	0.599	1.00
143_G	146_V	0.598	1.00
213_G	216_E	0.598	1.00
56_G	59_F	0.596	1.00
330_C	333_A	0.594	1.00
376_F	401_A	0.594	1.00
336_L	340_G	0.593	1.00
321_F	333_A	0.592	1.00
144_L	221_M	0.591	1.00
415_G	419_S	0.590	1.00
416_F	420_I	0.587	1.00
77_F	216_E	0.586	1.00
402_A	407_L	0.586	1.00
109_L	113_S	0.586	1.00
78_C	90_G	0.584	1.00
237_L	240_A	0.582	1.00
192_E	195_P	0.582	1.00
183_G	255_L	0.581	1.00
96_V	369_Y	0.580	1.00
119_W	287_G	0.579	1.00
248_I	252_L	0.579	1.00
23_V	155_A	0.578	1.00
327_K	331_W	0.578	1.00
396_M	399_I	0.576	1.00
401_A	407_L	0.576	1.00
35_S	39_I	0.576	1.00
200_G	203_T	0.575	1.00
173_L	256_L	0.573	1.00
81_A	90_G	0.572	1.00
9_P	74_K	0.572	1.00
133_A	342_V	0.572	1.00
229_E	233_K	0.571	1.00
37_I	40_V	0.570	1.00
61_F	65_A	0.570	1.00
142_T	327_K	0.567	1.00
70_K	389_K	0.566	1.00
269_F	272_S	0.566	1.00
53_A	212_F	0.565	1.00
220_L	303_A	0.565	1.00
168_I	278_L	0.564	1.00
101_E	303_A	0.564	1.00
409_E	414_P	0.561	1.00
41_K	203_T	0.561	1.00
287_G	291_I	0.560	1.00
386_G	389_K	0.560	1.00
84_A	380_K	0.560	1.00
108_Q	111_A	0.559	1.00
425_I	428_I	0.559	1.00
77_F	220_L	0.557	1.00
284_I	288_I	0.555	1.00
431_M	434_Q	0.555	1.00
108_Q	293_G	0.555	1.00
347_L	351_L	0.554	1.00
31_F	34_G	0.554	1.00
147_F	302_F	0.554	1.00
292_A	295_S	0.553	1.00
268_P	276_Y	0.550	1.00
113_S	125_L	0.548	1.00
198_A	202_W	0.548	1.00
395_A	407_L	0.547	1.00
426_I	430_T	0.545	1.00
38_A	208_A	0.544	1.00
137_L	301_L	0.544	1.00
184_I	189_K	0.544	1.00
421_G	428_I	0.543	1.00
395_A	403_V	0.543	1.00
53_A	209_F	0.541	1.00
395_A	401_A	0.541	1.00
320_C	324_K	0.541	1.00
412_S	419_S	0.540	1.00
160_A	163_F	0.539	1.00
414_P	419_S	0.539	1.00
102_M	344_S	0.539	1.00
93_N	370_T	0.539	1.00
88_W	431_M	0.538	1.00
152_N	156_V	0.536	1.00
63_Q	378_S	0.529	1.00
257_V	261_T	0.529	1.00
102_M	337_T	0.529	1.00
416_F	430_T	0.527	1.00
35_S	38_A	0.525	1.00
201_L	205_L	0.524	1.00
347_L	352_P	0.524	1.00
135_L	139_I	0.524	1.00
37_I	41_K	0.523	1.00
31_F	35_S	0.522	1.00
33_L	37_I	0.521	1.00
241_T	248_I	0.520	1.00
409_E	416_F	0.520	1.00
269_F	273_L	0.520	1.00
134_V	335_G	0.520	1.00
119_W	286_N	0.520	1.00
91_F	426_I	0.519	1.00
417_F	426_I	0.519	1.00
331_W	334_L	0.518	1.00
306_T	330_C	0.517	1.00
104_I	108_Q	0.517	1.00
76_S	219_G	0.516	1.00
273_L	281_I	0.516	1.00
23_V	26_T	0.515	1.00
301_L	334_L	0.514	1.00
109_L	136_G	0.514	1.00
172_A	177_L	0.513	1.00
73_E	223_V	0.513	1.00
161_A	284_I	0.511	1.00
225_L	234_S	0.511	1.00
60_V	216_E	0.511	1.00
151_E	295_S	0.511	1.00
106_G	109_L	0.511	1.00
38_A	204_G	0.511	1.00
47_L	50_F	0.511	1.00
100_S	366_M	0.510	1.00
31_F	162_I	0.510	1.00
50_F	250_I	0.509	1.00
151_E	158_K	0.509	1.00
28_G	158_K	0.509	1.00
25_C	217_V	0.508	1.00
132_Y	294_F	0.508	1.00
131_I	134_V	0.506	1.00
308_L	312_A	0.505	1.00
12_N	328_K	0.505	1.00
65_A	235_G	0.503	1.00
270_I	274_K	0.503	1.00
383_D	388_G	0.503	1.00
69_A	389_K	0.503	1.00
67_L	70_K	0.502	1.00
414_P	421_G	0.502	1.00
49_S	208_A	0.502	1.00
420_I	423_L	0.502	1.00
263_T	266_D	0.502	1.00
297_L	300_S	0.501	1.00
85_F	90_G	0.500	1.00
153_V	156_V	0.500	1.00
22_G	26_T	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3l1lA	2	0.9327	100	0.263	Contact Map
3giaA	1	0.9395	100	0.35	Contact Map
4djkA	2	0.8969	100	0.363	Contact Map
3dh4A	3	0.9395	99.2	0.834	Contact Map
2xq2A	2	0.9417	99.1	0.841	Contact Map
2jlnA	1	0.9013	98.8	0.859	Contact Map
4wgvA	2	0.8274	97.9	0.892	Contact Map
2a65A	2	0.9372	96.9	0.91	Contact Map
4us3A	1	0.8857	96.7	0.911	Contact Map
4xp4A	1	0.9305	96.5	0.913	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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