GREMLIN Database
YCGG - Uncharacterized protein YcgG
UniProt: P94382 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 253 (216)
Sequences: 418 (300)
Seq/√Len: 20.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
111_E231_R4.5861.00
79_G151_Y4.1221.00
175_F181_F3.9711.00
153_I173_V3.7021.00
57_A74_L3.6691.00
119_N123_H3.3621.00
218_G224_E3.0300.99
59_A74_L2.7820.99
106_S109_A2.6880.98
59_A71_L2.6800.98
68_A117_F2.6610.98
165_S202_L2.4780.97
40_F152_F2.3300.96
85_T89_A2.3000.96
119_N122_S2.2220.95
224_E227_Q2.2180.95
133_I143_E2.2050.95
44_P215_G2.1490.94
76_A147_D2.1380.94
154_L176_Q2.0400.92
218_G227_Q1.9810.91
176_Q181_F1.9800.91
60_G96_D1.9780.91
161_E208_A1.9780.91
127_K147_D1.9150.89
57_A91_L1.9090.89
41_P202_L1.8640.88
66_R124_Q1.8590.88
118_L129_W1.8050.86
75_L146_F1.8000.86
59_A93_V1.7250.84
29_L94_L1.7250.84
45_G184_L1.7210.83
176_Q184_L1.7110.83
72_A146_F1.6780.82
71_L117_F1.6710.82
118_L199_R1.6440.80
35_D39_T1.6200.79
63_R97_T1.5880.78
137_P211_H1.5850.78
122_S242_F1.5840.78
130_P177_P1.5760.78
164_R207_Q1.5540.76
26_F30_A1.5330.75
180_V202_L1.5260.75
68_A121_L1.5210.75
164_R205_Y1.5080.74
124_Q146_F1.4740.73
122_S244_Y1.4410.71
129_W199_R1.4380.71
95_F171_F1.4360.70
119_N137_P1.4230.70
76_A126_E1.4220.70
214_L240_C1.3810.67
47_Q182_D1.3740.67
48_A90_S1.3640.66
33_L39_T1.3560.66
44_P168_F1.3550.66
208_A234_E1.3330.65
71_L93_V1.3060.63
195_S224_E1.2880.62
26_F49_F1.2570.60
19_P22_Q1.2390.59
122_S207_Q1.2230.58
44_P194_M1.2140.57
175_F184_L1.2050.57
45_G176_Q1.2030.56
44_P156_A1.1920.56
43_I214_L1.1740.55
48_A168_F1.1740.55
178_R225_W1.1730.55
61_D179_W1.1720.54
135_A226_K1.1700.54
48_A54_L1.1630.54
86_G169_P1.1590.54
175_F182_D1.1570.53
32_T40_F1.1400.52
43_I46_R1.1290.52
128_E204_A1.1260.51
184_L194_M1.1140.51
40_F48_A1.1100.50
78_Y126_E1.1080.50
91_L106_S1.1070.50
75_L96_D1.1070.50
138_E223_R1.0960.49
163_R209_P1.0880.49
183_D234_E1.0860.49
123_H242_F1.0790.48
174_T215_G1.0660.48
107_I229_F1.0590.47
65_N120_R1.0520.47
155_C180_V1.0430.46
154_L175_F1.0330.45
109_A138_E1.0290.45
171_F223_R1.0240.45
181_F184_L1.0240.45
23_R27_E1.0220.45
38_D60_G1.0140.44
45_G181_F1.0060.44
20_E24_I1.0040.44
24_I66_R0.9980.43
51_T78_Y0.9950.43
81_I85_T0.9940.43
177_P195_S0.9930.43
112_E135_A0.9910.43
142_W230_L0.9900.43
165_S233_D0.9860.42
146_F156_A0.9820.42
63_R98_P0.9810.42
181_F227_Q0.9780.42
59_A91_L0.9630.41
105_Y109_A0.9590.41
27_E31_E0.9560.40
143_E155_C0.9360.39
111_E235_K0.9300.39
56_I94_L0.9270.39
31_E113_L0.9260.39
133_I228_Y0.9260.39
178_R227_Q0.9230.38
79_G194_M0.9190.38
79_G147_D0.9160.38
176_Q208_A0.9120.38
69_E124_Q0.9080.37
224_E228_Y0.9060.37
33_L52_D0.9040.37
226_K242_F0.9030.37
44_P152_F0.8970.37
143_E151_Y0.8960.37
90_S175_F0.8930.37
142_W202_L0.8900.36
185_N211_H0.8860.36
30_A49_F0.8850.36
217_Y224_E0.8830.36
114_F217_Y0.8830.36
143_E174_T0.8810.36
154_L230_L0.8780.36
35_D167_S0.8770.36
55_R222_N0.8710.35
139_H244_Y0.8610.35
59_A95_F0.8610.35
62_P113_L0.8590.34
150_P184_L0.8570.34
132_D150_P0.8560.34
133_I145_C0.8540.34
35_D128_E0.8520.34
94_L211_H0.8430.34
61_D98_P0.8400.33
143_E228_Y0.8360.33
180_V229_F0.8340.33
145_C213_Q0.8210.32
54_L67_T0.8210.32
95_F137_P0.8190.32
67_T169_P0.8150.32
152_F165_S0.8100.32
29_L200_S0.8070.31
178_R224_E0.8040.31
61_D93_V0.7970.31
90_S243_S0.7960.31
125_D158_P0.7960.31
193_N200_S0.7940.31
48_A152_F0.7940.31
57_A93_V0.7930.31
176_Q188_T0.7930.31
60_G76_A0.7910.31
150_P175_F0.7890.30
134_P139_H0.7860.30
143_E178_R0.7830.30
40_F202_L0.7790.30
202_L230_L0.7780.30
27_E128_E0.7770.30
155_C229_F0.7710.29
111_E212_P0.7700.29
41_P94_L0.7700.29
136_D159_G0.7690.29
162_A202_L0.7680.29
110_Y171_F0.7680.29
128_E147_D0.7680.29
118_L124_Q0.7630.29
176_Q183_D0.7620.29
180_V208_A0.7590.29
63_R116_R0.7520.28
31_E112_E0.7470.28
92_V239_K0.7440.28
54_L92_V0.7410.28
78_Y188_T0.7390.28
140_Y223_R0.7380.28
69_E78_Y0.7310.27
130_P150_P0.7310.27
211_H225_W0.7290.27
163_R211_H0.7290.27
49_F76_A0.7280.27
111_E182_D0.7210.27
24_I77_E0.7180.27
58_F165_S0.7160.27
222_N235_K0.7150.27
211_H233_D0.7140.26
40_F187_S0.7120.26
78_Y174_T0.7110.26
94_L239_K0.7110.26
39_T143_E0.7090.26
106_S207_Q0.7070.26
60_G64_E0.7060.26
195_S198_I0.7050.26
93_V192_R0.7050.26
122_S164_R0.7050.26
58_F177_P0.7040.26
120_R144_F0.6960.26
45_G175_F0.6910.25
170_F193_N0.6910.25
146_F177_P0.6900.25
176_Q211_H0.6890.25
94_L144_F0.6880.25
91_L152_F0.6870.25
172_M242_F0.6860.25
198_I229_F0.6860.25
126_E147_D0.6820.25
20_E128_E0.6800.25
143_E223_R0.6790.25
173_V203_E0.6770.25
110_Y163_R0.6760.25
145_C155_C0.6750.25
43_I49_F0.6740.24
177_P217_Y0.6720.24
59_A207_Q0.6670.24
95_F198_I0.6630.24
30_A119_N0.6530.23
111_E213_Q0.6520.23
122_S208_A0.6510.23
46_R194_M0.6480.23
78_Y91_L0.6470.23
46_R208_A0.6400.23
211_H229_F0.6370.23
29_L201_R0.6350.23
88_Y187_S0.6340.23
94_L117_F0.6310.22
40_F156_A0.6290.22
229_F232_D0.6270.22
68_A173_V0.6270.22
40_F194_M0.6260.22
156_A178_R0.6250.22
58_F222_N0.6210.22
60_G124_Q0.6210.22
95_F228_Y0.6200.22
165_S205_Y0.6190.22
153_I175_F0.6170.22
57_A243_S0.6170.22
31_E204_A0.6160.22
40_F214_L0.6150.22
53_Q85_T0.6140.22
205_Y230_L0.6130.22
50_L139_H0.6120.22
49_F56_I0.6090.21
114_F229_F0.6080.21
157_T229_F0.6060.21
40_F177_P0.6030.21
94_L233_D0.6030.21
143_E176_Q0.6030.21
34_G128_E0.6010.21
110_Y190_F0.5990.21
75_L91_L0.5980.21
67_T117_F0.5980.21
156_A171_F0.5960.21
77_E93_V0.5890.21
65_N69_E0.5880.21
52_D158_P0.5870.21
154_L168_F0.5860.20
181_F240_C0.5810.20
153_I197_L0.5770.20
143_E180_V0.5750.20
201_R218_G0.5750.20
169_P198_I0.5740.20
77_E237_V0.5740.20
138_E203_E0.5710.20
41_P165_S0.5670.20
28_L56_I0.5640.20
115_W241_P0.5630.20
156_A174_T0.5620.19
63_R117_F0.5600.19
21_W225_W0.5600.19
114_F154_L0.5590.19
176_Q180_V0.5580.19
123_H204_A0.5570.19
44_P217_Y0.5570.19
114_F180_V0.5560.19
45_G89_A0.5540.19
54_L181_F0.5520.19
18_L23_R0.5440.19
155_C202_L0.5420.19
24_I73_P0.5380.19
56_I232_D0.5370.18
199_R216_W0.5370.18
174_T181_F0.5360.18
145_C175_F0.5360.18
77_E219_G0.5350.18
44_P48_A0.5340.18
66_R93_V0.5320.18
132_D135_A0.5320.18
41_P227_Q0.5300.18
156_A211_H0.5270.18
70_E197_L0.5250.18
67_T72_A0.5220.18
70_E203_E0.5220.18
47_Q145_C0.5210.18
86_G145_C0.5190.18
69_E138_E0.5190.18
65_N123_H0.5190.18
180_V230_L0.5180.18
52_D92_V0.5180.18
162_A165_S0.5160.18
148_G181_F0.5150.18
110_Y209_P0.5130.18
148_G175_F0.5130.18
31_E121_L0.5130.18
89_A202_L0.5120.17
40_F44_P0.5120.17
110_Y242_F0.5100.17
169_P234_E0.5060.17
133_I151_Y0.5050.17
89_A173_V0.5040.17
133_I217_Y0.5040.17
24_I65_N0.5030.17
175_F223_R0.5020.17
18_L147_D0.5020.17
132_D136_D0.5000.17
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4g6uB 1 0.4229 15.9 0.968 Contact Map
2g18A 3 0.3004 8.3 0.972 Contact Map
2gkpA 1 0.4071 8 0.972 Contact Map
2g8lA 2 0.3241 5.7 0.974 Contact Map
4qr2A 2 0.2332 5 0.975 Contact Map
1vykA 1 0.1344 4.5 0.975 Contact Map
3okpA 1 0.4348 4.1 0.976 Contact Map
3h3gB 1 0.0791 3.3 0.977 Contact Map
3ngxA 2 0.2569 3.3 0.977 Contact Map
4obuE 2 0.3439 3.1 0.977 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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