GREMLIN Database
CATX - Catalase X
UniProt: P94377 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 547 (476)
Sequences: 3122 (1158)
Seq/√Len: 53.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
270_N276_Q5.2601.00
480_V512_G4.1401.00
111_K152_E3.8191.00
92_Y330_V3.7131.00
122_A329_L3.2651.00
94_E119_K3.1521.00
465_R502_D3.0701.00
252_K291_E3.0121.00
386_L406_Y2.9811.00
90_H341_E2.9291.00
45_D48_N2.9121.00
461_G465_R2.8871.00
90_H388_I2.8441.00
252_K289_E2.8301.00
235_W294_A2.8011.00
51_T58_T2.7761.00
220_A256_R2.6821.00
298_S301_E2.6761.00
77_I379_V2.6531.00
124_V147_V2.5991.00
243_V296_I2.5971.00
171_P366_G2.5751.00
118_K152_E2.5631.00
73_D374_T2.4941.00
92_Y119_K2.4491.00
235_W247_Y2.4341.00
461_G501_A2.4281.00
469_E472_R2.3971.00
112_L156_W2.3881.00
73_D370_A2.3581.00
258_L266_I2.3291.00
455_N458_G2.2941.00
265_E269_K2.2511.00
123_F342_V2.2371.00
49_V58_T2.2371.00
467_F475_L2.2281.00
122_A147_V2.2211.00
223_R277_D2.2171.00
352_L358_F2.2071.00
102_E325_P2.2001.00
468_T471_E2.1961.00
507_K511_E2.1871.00
123_F345_A2.1731.00
215_P474_E2.1651.00
133_K188_N2.1501.00
289_E328_K2.1441.00
193_E487_R2.0891.00
186_V279_Y2.0791.00
293_Y323_W2.0041.00
111_K153_D1.9881.00
243_V298_S1.9871.00
291_E325_P1.9681.00
106_T324_K1.9641.00
50_R61_E1.9511.00
252_K328_K1.9501.00
379_V386_L1.9481.00
124_V329_L1.9401.00
210_T505_Y1.9361.00
221_N274_A1.9221.00
301_E304_E1.8900.99
188_N275_T1.8900.99
206_T501_A1.8790.99
221_N224_Q1.8670.99
49_V65_F1.8590.99
138_T273_H1.8570.99
46_N421_E1.8310.99
237_N241_K1.8010.99
201_Q424_I1.7880.99
312_P363_L1.7860.99
94_E330_V1.7860.99
264_E269_K1.7810.99
291_E328_K1.7780.99
385_Q405_Q1.7780.99
293_Y325_P1.7760.99
94_E328_K1.7750.99
281_A286_D1.7430.99
226_Q250_E1.7420.99
158_L356_L1.7410.99
158_L229_G1.7390.99
68_K176_D1.7370.99
206_T497_N1.7120.99
476_I508_R1.7050.99
87_A222_Y1.6790.99
488_K492_D1.6670.99
479_L509_V1.6660.99
471_E474_E1.6620.99
499_T506_G1.6550.98
350_G372_S1.6530.98
96_Y291_E1.6460.98
200_S494_M1.6460.98
464_Y476_I1.6390.98
138_T267_Q1.6370.98
276_Q280_D1.6330.98
114_Q118_K1.6240.98
298_S321_F1.6200.98
224_Q256_R1.6120.98
346_S379_V1.6110.98
223_R281_A1.6070.98
201_Q493_Q1.6070.98
95_A116_K1.6000.98
457_F497_N1.5900.98
69_I175_P1.5670.98
90_H123_F1.5620.98
289_E330_V1.5610.98
224_Q251_P1.5540.98
292_V329_L1.5470.98
510_A514_K1.5420.98
261_K477_T1.5380.98
292_V326_I1.5300.97
92_Y332_N1.5270.97
102_E324_K1.5210.97
113_F156_W1.5120.97
470_F474_E1.5080.97
349_T368_T1.5030.97
76_R81_V1.5020.97
463_T467_F1.5020.97
130_N181_F1.5020.97
65_F69_I1.5010.97
297_M316_W1.5010.97
47_Q421_E1.5000.97
38_R67_E1.5000.97
107_Y324_K1.4960.97
156_W247_Y1.4740.97
121_P333_K1.4670.97
58_T171_P1.4620.97
473_N477_T1.4550.97
498_F509_V1.4500.97
301_E321_F1.4420.96
305_L320_D1.4380.96
496_E500_K1.4270.96
473_N508_R1.4170.96
70_S376_R1.4130.96
138_T258_L1.3880.95
280_D284_N1.3720.95
119_K332_N1.3660.95
281_A284_N1.3620.95
147_V329_L1.3520.95
297_M309_P1.3450.95
115_E118_K1.3440.95
458_G462_E1.3440.95
107_Y296_I1.3330.94
495_I506_G1.3290.94
136_P139_L1.3220.94
249_F329_L1.3140.94
499_T510_A1.2980.94
469_E473_N1.2960.94
188_N338_Y1.2920.93
472_R504_D1.2880.93
211_F214_S1.2860.93
260_Q481_N1.2850.93
65_F366_G1.2770.93
178_V181_F1.2630.93
163_L208_M1.2590.92
94_E117_G1.2550.92
145_F227_G1.2460.92
43_V64_D1.2360.92
405_Q409_D1.2320.92
235_W245_V1.2200.91
92_Y328_K1.2200.91
121_P392_K1.2190.91
199_I209_I1.2180.91
226_Q251_P1.2130.91
177_L181_F1.2030.91
504_D507_K1.1990.91
104_I294_A1.1970.90
224_Q253_Q1.1960.90
249_F292_V1.1940.90
504_D508_R1.1920.90
358_F368_T1.1900.90
156_W356_L1.1900.90
206_T460_A1.1720.89
294_A326_I1.1720.89
105_S114_Q1.1660.89
184_D191_D1.1630.89
242_A299_D1.1590.89
87_A275_T1.1570.89
87_A335_P1.1510.89
234_K242_A1.1510.89
264_E268_G1.1460.88
38_R399_Q1.1430.88
104_I235_W1.1350.88
510_A515_K1.1280.88
265_E268_G1.1270.88
386_L408_V1.1270.88
259_T262_E1.1250.87
488_K491_Q1.1240.87
186_V283_E1.1230.87
464_Y508_R1.1190.87
492_D510_A1.1160.87
132_G183_P1.1150.87
111_K118_K1.1020.86
206_T457_F1.1010.86
479_L498_F1.0920.86
59_T446_V1.0850.86
495_I513_L1.0820.85
119_K330_V1.0820.85
60_L66_L1.0810.85
503_P507_K1.0800.85
305_L321_F1.0790.85
408_V411_A1.0780.85
122_A149_L1.0780.85
377_Y403_Q1.0770.85
102_E116_K1.0750.85
483_L486_C1.0740.85
111_K114_Q1.0650.84
297_M321_F1.0640.84
193_E425_M1.0540.84
461_G506_G1.0520.84
494_M497_N1.0440.83
309_P316_W1.0410.83
158_L249_F1.0410.83
220_A262_E1.0400.83
175_P369_F1.0370.83
247_Y356_L1.0360.83
89_A278_L1.0350.83
250_E323_W1.0340.83
218_I258_L1.0280.82
189_I276_Q1.0270.82
123_F388_I1.0260.82
87_A338_Y1.0240.82
136_P267_Q1.0200.82
96_Y328_K1.0160.81
220_A258_L1.0160.81
38_R71_H1.0150.81
112_L353_V1.0110.81
58_T65_F1.0110.81
277_D281_A1.0020.81
147_V249_F1.0020.81
88_G124_V0.9990.80
142_P178_V0.9990.80
178_V363_L0.9950.80
261_K265_E0.9920.80
425_M490_I0.9910.80
195_I199_I0.9880.80
480_V513_L0.9850.79
220_A273_H0.9850.79
149_L158_L0.9770.79
267_Q271_F0.9760.79
119_K328_K0.9760.79
248_H323_W0.9640.78
390_S393_K0.9640.78
348_G372_S0.9640.78
218_I260_Q0.9630.78
468_T472_R0.9630.78
229_G233_Y0.9600.78
317_Y462_E0.9600.78
200_S490_I0.9590.78
492_D496_E0.9580.78
465_R501_A0.9540.77
424_I493_Q0.9540.77
234_K357_D0.9540.77
130_N180_A0.9500.77
241_K300_D0.9490.77
281_A288_P0.9460.77
262_E265_E0.9440.76
431_A434_D0.9360.76
126_F222_Y0.9360.76
307_F317_Y0.9330.76
464_Y472_R0.9300.75
208_M460_A0.9300.75
184_D194_R0.9260.75
462_E466_R0.9250.75
139_L271_F0.9240.75
441_H445_D0.9210.75
298_S305_L0.9210.75
35_L46_N0.9210.75
73_D377_Y0.9130.74
104_I156_W0.9110.74
218_I263_A0.9090.74
340_A401_G0.9080.74
196_F494_M0.9070.74
208_M230_V0.9070.74
210_T475_L0.9060.73
476_I509_V0.9060.73
372_S383_Y0.9050.73
483_L494_M0.9050.73
124_V249_F0.9040.73
236_V357_D0.9030.73
250_E318_K0.9020.73
95_A104_I0.9020.73
476_I512_G0.9020.73
206_T494_M0.9020.73
385_Q406_Y0.9010.73
130_N190_Q0.9000.73
476_I505_Y0.8960.73
462_E465_R0.8960.73
190_Q271_F0.8950.73
461_G502_D0.8920.72
300_D304_E0.8920.72
95_A114_Q0.8890.72
464_Y475_L0.8890.72
497_N501_A0.8850.72
252_K330_V0.8840.72
491_Q513_L0.8820.71
128_T135_S0.8810.71
147_V292_V0.8800.71
266_I273_H0.8790.71
156_W235_W0.8770.71
241_K298_S0.8760.71
112_L122_A0.8740.71
495_I499_T0.8730.71
95_A102_E0.8720.71
486_C491_Q0.8720.71
60_L69_I0.8720.71
198_F363_L0.8710.70
194_R419_N0.8690.70
333_K336_E0.8680.70
453_R456_N0.8640.70
337_N401_G0.8630.70
266_I269_K0.8620.70
103_P114_Q0.8620.70
136_P271_F0.8620.70
180_A190_Q0.8610.70
163_L177_L0.8590.69
421_E430_E0.8590.69
108_T113_F0.8580.69
307_F458_G0.8560.69
310_L360_D0.8520.69
247_Y292_V0.8520.69
51_T362_K0.8480.68
218_I474_E0.8470.68
468_T474_E0.8460.68
479_L501_A0.8440.68
300_D303_P0.8430.68
428_L432_K0.8420.68
475_L479_L0.8410.68
211_F463_T0.8380.67
76_R182_Q0.8370.67
71_H399_Q0.8360.67
386_L409_D0.8310.67
70_S74_R0.8290.67
499_T507_K0.8280.67
318_K323_W0.8270.66
260_Q264_E0.8270.66
333_K341_E0.8260.66
501_A505_Y0.8240.66
222_Y274_A0.8220.66
112_L118_K0.8200.66
148_K347_F0.8190.66
466_R472_R0.8180.66
114_Q152_E0.8110.65
346_S375_Q0.8100.65
139_L267_Q0.8100.65
233_Y368_T0.8090.65
236_V240_G0.8090.65
348_G383_Y0.8090.65
203_P497_N0.8060.64
287_Y332_N0.8050.64
440_P446_V0.8040.64
303_P443_E0.8030.64
109_R240_G0.8010.64
34_T431_A0.8010.64
109_R354_D0.8010.64
281_A287_Y0.7970.64
46_N68_K0.7950.63
442_V445_D0.7940.63
74_R377_Y0.7900.63
229_G247_Y0.7900.63
108_T235_W0.7870.63
205_A494_M0.7870.63
372_S376_R0.7850.62
432_K435_G0.7840.62
47_Q430_E0.7830.62
38_R384_L0.7830.62
428_L431_A0.7800.62
158_L247_Y0.7800.62
105_S116_K0.7770.62
393_K396_A0.7770.62
102_E326_I0.7770.62
200_S493_Q0.7760.62
268_G271_F0.7760.62
214_S474_E0.7740.61
306_D458_G0.7730.61
96_Y325_P0.7730.61
130_N142_P0.7720.61
483_L513_L0.7690.61
162_N225_M0.7670.61
444_G448_R0.7640.60
370_A374_T0.7630.60
251_P255_I0.7620.60
107_Y243_V0.7610.60
337_N340_A0.7570.60
95_A326_I0.7540.59
161_N167_F0.7540.59
457_F500_K0.7530.59
168_I363_L0.7530.59
238_E241_K0.7520.59
95_A103_P0.7520.59
76_R82_V0.7510.59
95_A105_S0.7500.59
499_T503_P0.7500.59
374_T377_Y0.7490.59
37_N64_D0.7480.59
130_N177_L0.7470.59
93_F122_A0.7470.59
275_T338_Y0.7470.59
173_K421_E0.7460.58
464_Y504_D0.7410.58
235_W296_I0.7390.58
66_L369_F0.7370.58
148_K158_L0.7330.57
381_A403_Q0.7310.57
229_G246_K0.7310.57
503_P509_V0.7280.57
390_S394_H0.7280.57
202_S422_P0.7270.56
61_E368_T0.7250.56
298_S304_E0.7240.56
464_Y479_L0.7230.56
233_Y352_L0.7230.56
221_N256_R0.7230.56
315_L318_K0.7220.56
480_V484_S0.7210.56
39_Q384_L0.7200.56
47_Q173_K0.7180.56
113_F326_I0.7170.55
93_F292_V0.7150.55
105_S115_E0.7150.55
88_G342_V0.7140.55
133_K338_Y0.7140.55
398_N423_S0.7140.55
306_D320_D0.7130.55
197_D420_Y0.7130.55
177_L212_L0.7130.55
86_G126_F0.7130.55
139_L218_I0.7090.55
220_A274_A0.7070.54
168_I198_F0.7050.54
283_E334_N0.7040.54
207_H315_L0.7020.54
325_P328_K0.7010.54
130_N135_S0.7010.54
165_I211_F0.7010.54
224_Q281_A0.7000.54
301_E305_L0.6980.53
190_Q272_N0.6970.53
52_V442_V0.6960.53
72_F382_N0.6960.53
186_V336_E0.6960.53
94_E116_K0.6940.53
195_I482_T0.6940.53
487_R490_I0.6930.53
477_T481_N0.6860.52
200_S483_L0.6860.52
76_R401_G0.6840.52
226_Q318_K0.6830.52
439_T442_V0.6830.52
76_R79_E0.6830.52
214_S471_E0.6820.52
163_L230_V0.6810.52
335_P342_V0.6790.51
147_V158_L0.6760.51
54_N449_E0.6750.51
163_L212_L0.6720.51
132_G188_N0.6720.51
109_R153_D0.6710.51
210_T464_Y0.6700.51
104_I326_I0.6700.51
165_I233_Y0.6690.50
229_G248_H0.6690.50
351_V383_Y0.6680.50
258_L273_H0.6680.50
39_Q351_V0.6670.50
342_V388_I0.6670.50
379_V383_Y0.6660.50
215_P471_E0.6660.50
199_I205_A0.6650.50
267_Q272_N0.6640.50
202_S424_I0.6630.50
130_N213_F0.6620.50
55_R308_D0.6600.49
135_S272_N0.6600.49
221_N273_H0.6590.49
96_Y116_K0.6570.49
390_S407_R0.6570.49
81_V377_Y0.6560.49
206_T500_K0.6550.49
253_Q288_P0.6550.49
65_F231_H0.6540.49
124_V158_L0.6540.49
120_T149_L0.6530.49
77_I386_L0.6530.49
67_E399_Q0.6520.49
81_V384_L0.6520.49
142_P181_F0.6520.49
180_A194_R0.6500.48
50_R448_R0.6500.48
126_F225_M0.6500.48
494_M498_F0.6450.48
250_E293_Y0.6450.48
303_P441_H0.6430.48
61_E365_Q0.6430.48
33_D396_A0.6410.47
130_N178_V0.6380.47
104_I296_I0.6380.47
177_L180_A0.6360.47
491_Q495_I0.6360.47
210_T463_T0.6340.47
66_L69_I0.6330.47
130_N192_G0.6310.46
90_H121_P0.6300.46
149_L356_L0.6300.46
218_I478_N0.6290.46
423_S428_L0.6280.46
177_L209_I0.6270.46
213_F498_F0.6270.46
297_M302_H0.6270.46
406_Y409_D0.6260.46
199_I213_F0.6260.46
312_P366_G0.6260.46
222_Y258_L0.6250.46
365_Q368_T0.6250.46
495_I515_K0.6250.46
196_F479_L0.6230.46
492_D514_K0.6210.45
484_S491_Q0.6210.45
122_A249_F0.6210.45
235_W243_V0.6200.45
430_E435_G0.6200.45
207_H216_W0.6200.45
169_R456_N0.6190.45
129_V167_F0.6190.45
181_F199_I0.6190.45
113_F353_V0.6190.45
72_F419_N0.6140.45
508_R512_G0.6120.44
156_W349_T0.6110.44
213_F479_L0.6110.44
202_S421_E0.6100.44
252_K293_Y0.6070.44
317_Y466_R0.6060.44
216_W248_H0.6060.44
189_I280_D0.6010.43
85_R183_P0.6000.43
211_F226_Q0.5990.43
476_I480_V0.5980.43
228_S248_H0.5980.43
382_N419_N0.5970.43
131_H271_F0.5970.43
351_V384_L0.5960.43
85_R272_N0.5960.43
37_N41_H0.5960.43
492_D516_V0.5940.43
220_A224_Q0.5930.42
341_E388_I0.5930.42
239_E300_D0.5920.42
400_E419_N0.5920.42
153_D353_V0.5920.42
66_L74_R0.5910.42
160_G229_G0.5900.42
247_Y294_A0.5900.42
304_E307_F0.5900.42
135_S271_F0.5890.42
301_E320_D0.5890.42
437_D440_P0.5880.42
121_P388_I0.5880.42
210_T509_V0.5860.42
142_P163_L0.5850.42
445_D449_E0.5850.42
303_P442_V0.5840.42
104_I247_Y0.5830.41
279_Y283_E0.5820.41
385_Q407_R0.5820.41
142_P208_M0.5820.41
168_I175_P0.5810.41
66_L368_T0.5810.41
41_H351_V0.5810.41
196_F201_Q0.5810.41
491_Q514_K0.5800.41
499_T515_K0.5800.41
151_T353_V0.5800.41
85_R132_G0.5790.41
213_F456_N0.5790.41
243_V321_F0.5780.41
483_L491_Q0.5780.41
131_H139_L0.5780.41
214_S218_I0.5770.41
499_T517_S0.5770.41
429_K432_K0.5770.41
71_H400_E0.5760.41
352_L368_T0.5760.41
278_L288_P0.5760.41
475_L478_N0.5760.41
96_Y104_I0.5750.41
191_D194_R0.5740.40
47_Q202_S0.5740.40
305_L317_Y0.5730.40
223_R253_Q0.5730.40
200_S495_I0.5720.40
70_S372_S0.5710.40
485_T491_Q0.5710.40
158_L292_V0.5710.40
94_E115_E0.5690.40
298_S320_D0.5690.40
231_H359_S0.5690.40
282_I288_P0.5680.40
251_P256_R0.5670.40
162_N167_F0.5660.40
375_Q482_T0.5650.40
237_N243_V0.5640.39
424_I490_I0.5630.39
261_K264_E0.5620.39
126_F331_L0.5620.39
302_H309_P0.5610.39
496_E499_T0.5610.39
88_G123_F0.5610.39
102_E293_Y0.5600.39
82_V178_V0.5580.39
296_I324_K0.5580.39
222_Y225_M0.5570.39
229_G232_A0.5560.39
465_R472_R0.5560.39
126_F227_G0.5550.39
95_A115_E0.5550.39
230_V312_P0.5550.39
162_N217_G0.5550.39
359_S364_L0.5540.38
464_Y485_T0.5540.38
128_T274_A0.5530.38
398_N428_L0.5530.38
482_T485_T0.5520.38
108_T114_Q0.5510.38
253_Q281_A0.5510.38
253_Q290_W0.5510.38
234_K438_H0.5500.38
142_P258_L0.5500.38
111_K115_E0.5490.38
130_N274_A0.5470.38
38_R397_T0.5470.38
299_D303_P0.5470.38
193_E486_C0.5470.38
86_G222_Y0.5460.38
131_H190_Q0.5450.38
52_V441_H0.5450.38
87_A334_N0.5440.37
469_E508_R0.5440.37
267_Q273_H0.5420.37
69_I74_R0.5420.37
135_S142_P0.5410.37
346_S383_Y0.5400.37
90_H150_Y0.5400.37
67_E70_S0.5390.37
96_Y117_G0.5390.37
479_L494_M0.5390.37
309_P359_S0.5380.37
92_Y121_P0.5350.37
325_P330_V0.5350.37
49_V171_P0.5350.37
165_I463_T0.5350.37
95_A112_L0.5340.36
475_L505_Y0.5340.36
214_S467_F0.5340.36
218_I266_I0.5330.36
59_T62_N0.5320.36
192_G195_I0.5320.36
110_A356_L0.5320.36
41_H63_Y0.5300.36
133_K339_H0.5290.36
132_G191_D0.5290.36
495_I510_A0.5290.36
160_G230_V0.5290.36
153_D354_D0.5270.36
460_A505_Y0.5270.36
142_P177_L0.5270.36
467_F474_E0.5260.36
228_S318_K0.5250.36
81_V419_N0.5230.35
82_V374_T0.5230.35
498_F505_Y0.5230.35
244_L360_D0.5230.35
69_I348_G0.5220.35
142_P190_Q0.5220.35
43_V48_N0.5220.35
200_S422_P0.5220.35
179_H370_A0.5210.35
282_I287_Y0.5200.35
226_Q255_I0.5200.35
37_N63_Y0.5190.35
350_G383_Y0.5190.35
492_D515_K0.5180.35
307_F462_E0.5180.35
210_T479_L0.5160.35
400_E410_R0.5160.35
368_T400_E0.5160.35
34_T42_P0.5140.35
437_D448_R0.5140.35
491_Q515_K0.5130.34
109_R236_V0.5130.34
423_S493_Q0.5130.34
82_V168_I0.5120.34
159_V167_F0.5120.34
173_K202_S0.5120.34
178_V312_P0.5110.34
52_V59_T0.5100.34
129_V161_N0.5100.34
489_E493_Q0.5080.34
210_T460_A0.5080.34
156_W296_I0.5070.34
224_Q286_D0.5060.34
142_P212_L0.5060.34
336_E410_R0.5060.34
298_S302_H0.5050.34
482_T486_C0.5040.34
339_H401_G0.5040.34
104_I113_F0.5020.33
385_Q409_D0.5020.33
179_H400_E0.5020.33
510_A516_V0.5020.33
400_E409_D0.5010.33
484_S513_L0.5010.33
112_L152_E0.5010.33
385_Q400_E0.5010.33
257_N474_E0.5010.33
81_V185_P0.5000.33
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3ttvA 4 0.9799 100 0.225 Contact Map
4cabA 4 0.9159 100 0.228 Contact Map
1sy7A 4 0.9232 100 0.231 Contact Map
4qolA 4 0.8739 100 0.236 Contact Map
1qwlA 4 0.883 100 0.236 Contact Map
2isaA 5 0.8793 100 0.236 Contact Map
2j2mA 4 0.872 100 0.236 Contact Map
2iufA 4 0.9378 100 0.236 Contact Map
1si8A 4 0.8629 100 0.237 Contact Map
1gweA 4 0.9031 100 0.238 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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