YXLA - BACSU - GREMLIN Contacts

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YXLA - Putative purine-cytosine permease YxlA

UniProt:	P94369	Sequences: MKVERRTIEYIPNEERHGKAKDLFPVWFGANMHITTLVTGTIPVAMGLNLFWSVAAIICGTLIGAIFMASHSAQGPQLGIPQMIQSRAQFGVIGAILPLFLVMFIYLGFFASSTILAAGTLSSFVPIPGSWSIIGLSAVCFLLTIFGHDLIHKMQKILSWTSFAVFFAATILIFQLPIPAGSWIPGAIDLPIFLVAVSAVATWQLAYAPYVADYSRYLPVKTPASKTFWYSYAGTSVSSIWMMLLGALLTTSLPDFTANSGSQIVQLFGPFSFIMLIIVLFGQMAINVFNLYGAFMSTTTTLEPFLKLKVTPKVRIIMILGVTLVGTVLSLLGQSNFMELFLNFIFFISYFLIPWTAINLVDYYFVRHGKYQVKAMFDVNGPYGKVNWITTIAFVLSILLEIPFINTSFYIGPLAKMFGGGDIAWIIGLAVPSVLYYVLMKPRLKKRAGYQEKLSSL	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	457 (419)
Sequences:	4806 (3126)
Seq/√Len:	152.7

ECOLI - ALLP CODB
BACSU - YXLA ALLP
SULSO - Q97WS4 Q97X50 Q97XP6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
361_V	433_S	6.972	1.00
372_Q	375_A	5.900	1.00
361_V	437_Y	5.671	1.00
75_G	212_A	4.354	1.00
396_L	435_L	4.175	1.00
13_N	220_V	4.158	1.00
54_V	244_L	4.078	1.00
393_A	435_L	3.546	1.00
397_S	432_P	3.220	1.00
393_A	397_S	3.214	1.00
171_I	175_Q	3.210	1.00
365_F	433_S	3.126	1.00
397_S	435_L	2.958	1.00
193_F	197_V	2.903	1.00
357_A	361_V	2.813	1.00
362_D	367_R	2.795	1.00
393_A	439_L	2.780	1.00
375_A	378_D	2.770	1.00
43_P	196_A	2.727	1.00
259_N	262_S	2.664	1.00
59_C	197_V	2.594	1.00
400_L	431_V	2.593	1.00
12_P	15_E	2.584	1.00
56_A	193_F	2.582	1.00
77_Q	224_A	2.550	1.00
49_N	52_W	2.528	1.00
388_W	392_I	2.504	1.00
391_T	395_V	2.378	1.00
365_F	437_Y	2.321	1.00
30_A	289_F	2.281	1.00
287_N	290_N	2.275	1.00
167_F	171_I	2.214	1.00
53_S	247_A	2.200	1.00
170_T	241_W	2.176	1.00
358_I	394_F	2.157	1.00
357_A	429_L	2.118	1.00
435_L	439_L	2.110	1.00
63_I	201_A	2.101	1.00
16_R	79_G	2.060	1.00
431_V	435_L	2.032	1.00
401_E	428_G	2.029	1.00
72_S	215_S	1.976	1.00
97_L	391_T	1.973	1.00
6_R	15_E	1.963	1.00
426_I	430_A	1.926	1.00
93_I	96_I	1.892	1.00
109_F	112_S	1.891	1.00
44_V	250_T	1.888	1.00
131_W	135_G	1.877	1.00
357_A	432_P	1.864	1.00
114_T	140_C	1.861	1.00
110_F	287_N	1.833	1.00
138_A	142_L	1.825	1.00
20_A	226_K	1.815	1.00
392_I	439_L	1.811	1.00
372_Q	382_P	1.800	1.00
74_Q	85_Q	1.788	1.00
117_A	136_L	1.773	1.00
89_Q	362_D	1.756	1.00
327_T	330_S	1.749	1.00
397_S	431_V	1.740	1.00
6_R	9_E	1.730	1.00
225_S	229_W	1.729	1.00
437_Y	441_K	1.722	1.00
434_V	438_V	1.715	1.00
52_W	189_D	1.712	1.00
43_P	53_S	1.703	1.00
50_L	54_V	1.702	1.00
219_P	226_K	1.696	1.00
164_A	168_A	1.683	1.00
88_A	371_Y	1.676	1.00
153_K	156_K	1.661	1.00
69_A	232_Y	1.659	1.00
146_F	150_L	1.659	1.00
95_A	300_T	1.658	1.00
55_A	193_F	1.645	1.00
140_C	287_N	1.643	1.00
438_V	441_K	1.628	1.00
430_A	433_S	1.614	1.00
412_G	415_A	1.611	1.00
358_I	393_A	1.560	1.00
433_S	437_Y	1.552	1.00
51_F	55_A	1.544	1.00
122_S	132_S	1.535	1.00
22_D	156_K	1.526	1.00
85_Q	212_A	1.522	1.00
57_I	243_M	1.518	1.00
108_G	344_F	1.508	1.00
97_L	386_V	1.496	1.00
390_T	393_A	1.491	1.00
399_L	403_P	1.465	1.00
396_L	431_V	1.462	1.00
75_G	215_S	1.459	1.00
375_A	382_P	1.447	1.00
119_G	259_N	1.438	1.00
430_A	434_V	1.429	1.00
90_F	390_T	1.428	1.00
320_L	324_L	1.410	1.00
255_D	266_Q	1.409	1.00
134_I	138_A	1.391	1.00
358_I	390_T	1.380	1.00
179_P	182_S	1.370	1.00
220_V	225_S	1.367	1.00
226_K	230_Y	1.364	1.00
44_V	53_S	1.353	1.00
386_V	391_T	1.352	1.00
110_F	326_G	1.348	1.00
354_P	428_G	1.346	1.00
362_D	366_V	1.329	1.00
358_I	397_S	1.307	1.00
19_K	22_D	1.306	1.00
357_A	433_S	1.297	1.00
73_A	77_Q	1.294	1.00
48_L	56_A	1.287	1.00
178_I	181_G	1.282	1.00
307_K	310_V	1.272	1.00
438_V	442_P	1.271	1.00
229_W	233_A	1.267	1.00
254_P	258_A	1.259	1.00
56_A	196_A	1.255	1.00
90_F	94_G	1.249	1.00
170_T	245_L	1.240	1.00
110_F	323_T	1.237	1.00
174_F	248_L	1.225	1.00
245_L	249_L	1.224	1.00
395_V	399_L	1.222	1.00
428_G	432_P	1.222	1.00
89_Q	359_N	1.221	1.00
404_F	427_I	1.219	1.00
70_S	364_Y	1.212	1.00
168_A	171_I	1.210	1.00
143_L	154_M	1.209	1.00
113_S	290_N	1.205	1.00
255_D	262_S	1.197	1.00
88_A	376_M	1.193	1.00
236_S	240_I	1.186	1.00
111_A	323_T	1.186	1.00
180_A	183_W	1.181	1.00
384_G	388_W	1.178	1.00
360_L	364_Y	1.176	1.00
141_F	323_T	1.169	1.00
263_Q	267_L	1.168	1.00
390_T	436_Y	1.162	1.00
114_T	137_S	1.156	1.00
217_Y	296_M	1.154	1.00
423_I	427_I	1.149	1.00
214_Y	293_G	1.146	1.00
55_A	59_C	1.145	1.00
153_K	157_I	1.144	1.00
63_I	197_V	1.139	1.00
56_A	197_V	1.139	1.00
328_V	332_L	1.134	1.00
389_I	439_L	1.133	1.00
366_V	437_Y	1.129	1.00
124_F	273_F	1.127	1.00
193_F	196_A	1.125	1.00
71_H	359_N	1.116	0.99
436_Y	440_M	1.115	0.99
93_I	385_K	1.113	0.99
106_Y	210_Y	1.110	0.99
375_A	381_G	1.096	0.99
130_S	134_I	1.092	0.99
87_R	95_A	1.088	0.99
179_P	184_I	1.087	0.99
193_F	200_V	1.087	0.99
6_R	11_I	1.085	0.99
356_T	360_L	1.085	0.99
118_A	132_S	1.078	0.99
431_V	434_V	1.077	0.99
190_L	194_L	1.075	0.99
61_T	243_M	1.069	0.99
373_V	377_F	1.068	0.99
108_G	345_I	1.066	0.99
101_L	352_L	1.066	0.99
57_I	61_T	1.062	0.99
389_I	393_A	1.061	0.99
59_C	193_F	1.050	0.99
241_W	245_L	1.047	0.99
410_Y	413_P	1.039	0.99
181_G	184_I	1.038	0.99
389_I	440_M	1.036	0.99
73_A	224_A	1.034	0.99
57_I	240_I	1.030	0.99
212_A	215_S	1.029	0.99
66_I	70_S	1.028	0.99
400_L	403_P	1.027	0.99
28_F	238_S	1.025	0.99
84_I	87_R	1.024	0.99
65_A	69_A	1.023	0.99
389_I	392_I	1.020	0.99
262_S	266_Q	1.018	0.99
6_R	12_P	1.014	0.99
113_S	287_N	1.012	0.99
58_I	240_I	1.010	0.99
34_I	283_Q	1.004	0.99
57_I	247_A	0.999	0.99
72_S	75_G	0.995	0.99
180_A	184_I	0.992	0.99
434_V	437_Y	0.989	0.99
411_I	415_A	0.986	0.99
208_A	356_T	0.983	0.99
282_G	286_I	0.980	0.99
205_L	353_I	0.978	0.99
74_Q	78_L	0.977	0.99
306_L	310_V	0.977	0.99
56_A	60_G	0.975	0.99
393_A	436_Y	0.972	0.99
255_D	258_A	0.967	0.99
149_D	153_K	0.967	0.99
124_F	276_L	0.964	0.99
378_D	381_G	0.960	0.98
173_I	177_P	0.960	0.98
220_V	226_K	0.958	0.98
173_I	249_L	0.956	0.98
240_I	244_L	0.954	0.98
229_W	232_Y	0.950	0.98
299_T	318_M	0.949	0.98
60_G	200_V	0.942	0.98
398_I	401_E	0.941	0.98
64_G	204_Q	0.940	0.98
52_W	55_A	0.935	0.98
90_F	98_P	0.934	0.98
94_G	391_T	0.932	0.98
124_F	277_I	0.927	0.98
60_G	197_V	0.925	0.98
107_L	322_V	0.919	0.98
361_V	366_V	0.917	0.98
198_S	426_I	0.916	0.98
23_L	215_S	0.915	0.98
263_Q	266_Q	0.915	0.98
40_G	246_G	0.914	0.98
115_I	118_A	0.909	0.98
67_F	208_A	0.907	0.98
109_F	345_I	0.906	0.98
305_F	310_V	0.906	0.98
32_M	162_S	0.906	0.98
155_Q	285_A	0.904	0.98
73_A	364_Y	0.903	0.98
168_A	172_L	0.901	0.98
293_G	297_S	0.900	0.98
27_W	83_M	0.899	0.98
127_I	132_S	0.897	0.98
292_Y	296_M	0.894	0.98
54_V	58_I	0.893	0.98
182_S	185_P	0.891	0.97
78_L	371_Y	0.885	0.97
200_V	203_W	0.884	0.97
320_L	323_T	0.882	0.97
210_Y	214_Y	0.882	0.97
227_T	231_S	0.879	0.97
400_L	427_I	0.879	0.97
82_Q	212_A	0.877	0.97
31_N	238_S	0.877	0.97
137_S	327_T	0.877	0.97
160_W	164_A	0.875	0.97
197_V	201_A	0.874	0.97
389_I	443_R	0.872	0.97
117_A	283_Q	0.871	0.97
179_P	183_W	0.870	0.97
294_A	322_V	0.866	0.97
433_S	436_Y	0.864	0.97
410_Y	414_L	0.863	0.97
162_S	286_I	0.863	0.97
326_G	329_L	0.860	0.97
186_G	189_D	0.859	0.97
361_V	365_F	0.858	0.97
41_T	116_L	0.854	0.97
228_F	232_Y	0.854	0.97
226_K	229_W	0.850	0.97
392_I	396_L	0.850	0.97
110_F	291_L	0.848	0.97
167_F	396_L	0.847	0.97
113_S	283_Q	0.847	0.97
160_W	163_F	0.847	0.97
412_G	422_D	0.844	0.97
101_L	348_I	0.844	0.97
38_V	41_T	0.843	0.97
87_R	300_T	0.840	0.96
396_L	403_P	0.839	0.96
435_L	438_V	0.839	0.96
398_I	403_P	0.836	0.96
36_T	39_T	0.833	0.96
12_P	16_R	0.833	0.96
58_I	135_G	0.832	0.96
32_M	286_I	0.830	0.96
392_I	395_V	0.827	0.96
388_W	443_R	0.826	0.96
234_G	238_S	0.824	0.96
83_M	297_S	0.821	0.96
316_I	320_L	0.814	0.96
163_F	167_F	0.812	0.96
216_R	292_Y	0.810	0.96
41_T	250_T	0.810	0.96
235_T	239_S	0.809	0.96
282_G	285_A	0.807	0.96
65_A	236_S	0.807	0.96
90_F	394_F	0.806	0.95
37_L	249_L	0.801	0.95
74_Q	359_N	0.800	0.95
71_H	211_V	0.799	0.95
196_A	200_V	0.799	0.95
118_A	122_S	0.794	0.95
262_S	265_V	0.792	0.95
350_Y	405_I	0.792	0.95
406_N	411_I	0.791	0.95
131_W	134_I	0.789	0.95
319_I	323_T	0.789	0.95
73_A	369_G	0.788	0.95
114_T	287_N	0.786	0.95
145_I	317_I	0.785	0.95
169_A	267_L	0.785	0.95
189_D	193_F	0.783	0.95
141_F	320_L	0.781	0.95
62_L	236_S	0.780	0.95
388_W	391_T	0.776	0.94
440_M	443_R	0.776	0.94
103_M	298_T	0.775	0.94
294_A	297_S	0.773	0.94
194_L	198_S	0.772	0.94
387_N	440_M	0.766	0.94
110_F	113_S	0.764	0.94
89_Q	358_I	0.762	0.94
148_H	217_Y	0.762	0.94
155_Q	288_V	0.762	0.94
61_T	203_W	0.761	0.94
260_S	267_L	0.761	0.94
387_N	390_T	0.760	0.94
76_P	218_L	0.758	0.94
61_T	239_S	0.757	0.94
393_A	432_P	0.757	0.94
358_I	432_P	0.757	0.94
185_P	188_I	0.757	0.94
35_T	283_Q	0.756	0.94
24_F	28_F	0.755	0.94
377_F	383_Y	0.753	0.94
82_Q	293_G	0.751	0.93
87_R	362_D	0.749	0.93
424_A	428_G	0.747	0.93
100_F	301_T	0.745	0.93
53_S	57_I	0.741	0.93
395_V	398_I	0.741	0.93
68_M	206_A	0.741	0.93
21_K	25_P	0.740	0.93
366_V	440_M	0.738	0.93
327_T	331_L	0.737	0.93
206_A	352_L	0.736	0.93
142_L	400_L	0.735	0.93
143_L	284_M	0.730	0.92
68_M	71_H	0.728	0.92
168_A	271_F	0.727	0.92
115_I	119_G	0.725	0.92
393_A	433_S	0.725	0.92
288_V	291_L	0.722	0.92
123_S	262_S	0.718	0.92
303_E	306_L	0.718	0.92
87_R	92_V	0.716	0.92
125_V	132_S	0.711	0.91
31_N	239_S	0.711	0.91
396_L	399_L	0.710	0.91
340_L	344_F	0.710	0.91
99_L	297_S	0.710	0.91
232_Y	236_S	0.707	0.91
207_Y	210_Y	0.707	0.91
398_I	402_I	0.707	0.91
164_A	171_I	0.705	0.91
93_I	384_G	0.704	0.91
201_A	205_L	0.704	0.91
117_A	143_L	0.703	0.91
189_D	194_L	0.701	0.91
397_S	433_S	0.699	0.91
97_L	395_V	0.698	0.91
371_Y	377_F	0.695	0.91
411_I	414_L	0.692	0.90
93_I	386_V	0.691	0.90
410_Y	415_A	0.689	0.90
316_I	319_I	0.688	0.90
185_P	192_I	0.687	0.90
76_P	227_T	0.687	0.90
140_C	284_M	0.687	0.90
224_A	228_F	0.686	0.90
121_L	132_S	0.686	0.90
18_G	148_H	0.685	0.90
80_I	85_Q	0.685	0.90
306_L	318_M	0.684	0.90
33_H	36_T	0.684	0.90
30_A	207_Y	0.684	0.90
69_A	228_F	0.678	0.89
397_S	400_L	0.678	0.89
48_L	52_W	0.676	0.89
279_V	283_Q	0.674	0.89
427_I	430_A	0.673	0.89
9_E	12_P	0.673	0.89
76_P	224_A	0.672	0.89
250_T	253_L	0.671	0.89
365_F	368_H	0.669	0.89
24_F	233_A	0.668	0.89
42_I	342_L	0.668	0.89
144_T	316_I	0.666	0.89
8_I	84_I	0.665	0.89
80_I	377_F	0.665	0.89
167_F	241_W	0.664	0.88
127_I	131_W	0.663	0.88
118_A	242_M	0.663	0.88
362_D	440_M	0.661	0.88
401_E	405_I	0.661	0.88
22_D	152_H	0.660	0.88
340_L	343_N	0.659	0.88
106_Y	294_A	0.658	0.88
108_G	348_I	0.658	0.88
283_Q	286_I	0.657	0.88
204_Q	235_T	0.657	0.88
34_I	37_L	0.656	0.88
111_A	115_I	0.656	0.88
276_L	285_A	0.654	0.88
102_V	210_Y	0.654	0.88
326_G	330_S	0.653	0.88
127_I	135_G	0.652	0.88
86_S	89_Q	0.651	0.87
65_A	283_Q	0.651	0.87
198_S	207_Y	0.649	0.87
86_S	95_A	0.649	0.87
249_L	253_L	0.646	0.87
111_A	329_L	0.646	0.87
60_G	64_G	0.644	0.87
46_M	192_I	0.642	0.87
11_I	79_G	0.642	0.87
199_A	342_L	0.641	0.87
19_K	219_P	0.639	0.86
88_A	367_R	0.638	0.86
191_P	194_L	0.638	0.86
110_F	140_C	0.637	0.86
72_S	227_T	0.635	0.86
71_H	360_L	0.634	0.86
233_A	237_V	0.634	0.86
431_V	440_M	0.634	0.86
147_G	292_Y	0.633	0.86
318_M	329_L	0.633	0.86
140_C	143_L	0.632	0.86
225_S	228_F	0.632	0.86
162_S	282_G	0.629	0.86
35_T	118_A	0.627	0.85
354_P	397_S	0.627	0.85
367_R	371_Y	0.626	0.85
30_A	283_Q	0.625	0.85
189_D	195_V	0.624	0.85
120_T	124_F	0.622	0.85
365_F	377_F	0.622	0.85
31_N	83_M	0.622	0.85
154_M	285_A	0.621	0.85
17_H	149_D	0.621	0.85
230_Y	234_G	0.620	0.85
36_T	203_W	0.620	0.85
397_S	428_G	0.619	0.85
172_L	175_Q	0.619	0.85
204_Q	207_Y	0.618	0.85
61_T	105_I	0.617	0.85
50_L	251_T	0.617	0.85
12_P	217_Y	0.616	0.84
98_P	109_F	0.615	0.84
38_V	116_L	0.614	0.84
92_V	379_V	0.614	0.84
403_P	407_T	0.614	0.84
317_I	321_G	0.614	0.84
281_F	285_A	0.614	0.84
153_K	158_L	0.612	0.84
110_F	141_F	0.612	0.84
40_G	43_P	0.612	0.84
427_I	431_V	0.610	0.84
130_S	396_L	0.609	0.84
193_F	399_L	0.608	0.84
370_K	373_V	0.604	0.83
30_A	204_Q	0.603	0.83
111_A	326_G	0.602	0.83
39_T	342_L	0.601	0.83
23_L	218_L	0.601	0.83
393_A	396_L	0.600	0.83
96_I	301_T	0.600	0.83
65_A	232_Y	0.600	0.83
97_L	394_F	0.600	0.83
324_L	328_V	0.599	0.83
224_A	227_T	0.599	0.83
204_Q	208_A	0.599	0.83
260_S	264_I	0.598	0.83
184_I	188_I	0.598	0.83
102_V	293_G	0.595	0.82
30_A	239_S	0.595	0.82
27_W	34_I	0.590	0.82
144_T	291_L	0.590	0.82
101_L	355_W	0.589	0.82
329_L	337_F	0.587	0.82
106_Y	290_N	0.587	0.82
36_T	246_G	0.586	0.81
295_F	300_T	0.586	0.81
106_Y	293_G	0.583	0.81
52_W	193_F	0.583	0.81
375_A	380_N	0.582	0.81
197_V	200_V	0.581	0.81
18_G	218_L	0.580	0.81
176_L	184_I	0.580	0.81
35_T	112_S	0.580	0.81
413_P	422_D	0.580	0.81
188_I	192_I	0.579	0.81
207_Y	289_F	0.578	0.81
301_T	322_V	0.578	0.81
155_Q	286_I	0.577	0.80
184_I	431_V	0.576	0.80
29_G	159_S	0.576	0.80
309_K	331_L	0.574	0.80
321_G	325_V	0.573	0.80
438_V	443_R	0.572	0.80
116_L	348_I	0.572	0.80
141_F	145_I	0.571	0.80
157_I	160_W	0.571	0.80
58_I	244_L	0.570	0.80
125_V	128_P	0.570	0.80
80_I	84_I	0.570	0.80
165_V	278_I	0.570	0.80
124_F	280_L	0.568	0.79
37_L	242_M	0.568	0.79
194_L	374_K	0.568	0.79
99_L	301_T	0.566	0.79
77_Q	369_G	0.565	0.79
358_I	436_Y	0.564	0.79
49_N	53_S	0.564	0.79
114_T	117_A	0.564	0.79
138_A	358_I	0.563	0.79
125_V	332_L	0.561	0.79
68_M	211_V	0.561	0.79
237_V	241_W	0.561	0.79
134_I	180_A	0.560	0.78
68_M	208_A	0.560	0.78
33_H	37_L	0.560	0.78
131_W	389_I	0.559	0.78
137_S	323_T	0.557	0.78
92_V	383_Y	0.557	0.78
169_A	249_L	0.556	0.78
324_L	400_L	0.556	0.78
145_I	280_L	0.554	0.78
93_I	392_I	0.553	0.78
39_T	203_W	0.552	0.77
13_N	277_I	0.552	0.77
170_T	248_L	0.552	0.77
119_G	262_S	0.551	0.77
179_P	185_P	0.551	0.77
51_F	186_G	0.550	0.77
126_P	132_S	0.549	0.77
20_A	230_Y	0.548	0.77
121_L	267_L	0.548	0.77
142_L	146_F	0.547	0.77
202_T	353_I	0.547	0.77
218_L	230_Y	0.546	0.77
118_A	133_I	0.546	0.77
69_A	238_S	0.545	0.77
397_S	401_E	0.545	0.77
44_V	247_A	0.544	0.76
82_Q	102_V	0.542	0.76
425_W	429_L	0.541	0.76
303_E	310_V	0.540	0.76
273_F	277_I	0.540	0.76
402_I	406_N	0.539	0.76
220_V	224_A	0.539	0.76
83_M	300_T	0.538	0.76
135_G	142_L	0.537	0.76
306_L	309_K	0.537	0.76
260_S	263_Q	0.536	0.75
199_A	202_T	0.534	0.75
9_E	15_E	0.534	0.75
206_A	425_W	0.534	0.75
107_L	348_I	0.532	0.75
80_I	87_R	0.531	0.75
8_I	87_R	0.530	0.75
105_I	345_I	0.527	0.74
151_I	288_V	0.527	0.74
103_M	111_A	0.526	0.74
210_Y	213_D	0.526	0.74
64_G	68_M	0.525	0.74
374_K	379_V	0.525	0.74
32_M	163_F	0.524	0.74
49_N	359_N	0.524	0.74
143_L	288_V	0.524	0.74
43_P	200_V	0.524	0.74
166_F	282_G	0.522	0.73
59_C	262_S	0.522	0.73
350_Y	401_E	0.521	0.73
39_T	235_T	0.521	0.73
61_T	240_I	0.520	0.73
361_V	436_Y	0.519	0.73
41_T	75_G	0.518	0.73
190_L	193_F	0.517	0.73
113_S	285_A	0.517	0.73
50_L	248_L	0.517	0.73
138_A	396_L	0.516	0.73
294_A	319_I	0.514	0.72
59_C	125_V	0.514	0.72
380_N	383_Y	0.514	0.72
31_N	234_G	0.514	0.72
135_G	395_V	0.512	0.72
263_Q	351_F	0.512	0.72
402_I	405_I	0.512	0.72
141_F	433_S	0.511	0.72
162_S	350_Y	0.510	0.72
97_L	403_P	0.510	0.72
27_W	33_H	0.509	0.72
104_F	344_F	0.509	0.72
289_F	293_G	0.509	0.72
34_I	263_Q	0.508	0.71
88_A	383_Y	0.508	0.71
345_I	367_R	0.507	0.71
106_Y	243_M	0.507	0.71
136_L	284_M	0.507	0.71
99_L	300_T	0.506	0.71
62_L	240_I	0.506	0.71
29_G	155_Q	0.506	0.71
134_I	331_L	0.506	0.71
303_E	307_K	0.505	0.71
368_H	384_G	0.505	0.71
71_H	74_Q	0.505	0.71
203_W	206_A	0.504	0.71
107_L	298_T	0.504	0.71
162_S	239_S	0.504	0.71
30_A	212_A	0.504	0.71
90_F	358_I	0.503	0.71
309_K	316_I	0.503	0.71
102_V	106_Y	0.502	0.71
204_Q	239_S	0.502	0.71
109_F	207_Y	0.502	0.71
193_F	391_T	0.501	0.70
304_P	309_K	0.500	0.70

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2jlnA	1	0.9344	100	0.229	Contact Map
4djkA	2	0.8753	99.3	0.858	Contact Map
3l1lA	2	0.8709	99.3	0.863	Contact Map
3giaA	1	0.8993	99.2	0.865	Contact Map
3dh4A	3	0.8906	99	0.88	Contact Map
2xq2A	2	0.8972	98.9	0.883	Contact Map
4wgvA	2	0.7834	98.8	0.886	Contact Map
4us3A	1	0.8206	95.9	0.934	Contact Map
2a65A	2	0.9059	95.6	0.936	Contact Map
2wswA	3	0.8009	94.8	0.939	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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