CYDD - BACSU - GREMLIN Contacts

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CYDD - ATP-binding/permease protein CydD

UniProt:	P94367	Sequences: MKKEEWILPYIKQNARLFVLVIFLGAVTIFSAAFLMFTSGFLISKAATRPENILLIYVPIVAVRTFGIARSVSRYVERLVGHHIILKIVSDMRVRLYNMLEPGALMLRSRFRTGDMLGILSEDIEHLQDAFLKTIFPAISALLLYAVSVIALGFFSWPFAILLALYLFVLVVLFPVVSLLVTRAKNAKLKSGRNVLYSRLTDAVMGVSDWMFSGRRHAFIDAYEKEERDWFELERKKQRFTRWRDFAAQCLVAGLILLMLFWTAGQQADGELAKTMIAAFVLVVFPLTEAFLPLSDALGEVPGYQDSIRRMNNVAPQPEASQTESGDQILDLQDVTLAFRDVTFSYDNSSQVLHNFSFTLRQGEKMALLGRSGSGKSTSLALIEGALKPDSGSVTLNGVETALLKDQIADAVAVLNQKPHLFDTSILNNIRLGNGEASDEDVRRAAKQVKLHDYIESLPDGYHTSVQETGIRFSGGERQRIALARILLQDTPIIILDEPTVGLDPITERELMETVFEVLKGKTILWITHHLAGVEAADKIVFLENGKTEMEGTHEELLAANERYRRLYHLDVPVK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	575 (556)
Sequences:	52497 (37155)
Seq/√Len:	1575.7

ECOLI - MDLA MSBA MDLB CYDD CYDC YOJI YDDA ARAG POTG
BACSU - CYDD YHEH YGAD YKNU YFIC SUNT BMRA YHEI YWJA YKNV YFIB CYDC YVRA OPUAA OPUCA TAGH
HALSA - Q9HSQ7 Q9HMX3 Q9HMW0 BTUDA
SULSO - Q97UJ9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
452_H	462_Y	4.586	1.00
364_E	539_K	4.410	1.00
338_A	359_T	4.395	1.00
341_D	355_N	4.352	1.00
361_R	364_E	4.344	1.00
424_T	428_N	4.054	1.00
539_K	551_E	4.007	1.00
554_H	564_Y	3.937	1.00
340_R	393_S	3.920	1.00
427_L	439_D	3.890	1.00
447_K	452_H	3.831	1.00
340_R	395_T	3.471	1.00
452_H	456_E	3.453	1.00
336_T	359_T	3.429	1.00
393_S	400_E	3.359	1.00
354_H	547_K	3.105	1.00
339_F	342_V	3.076	1.00
427_L	463_H	3.074	1.00
427_L	431_R	3.026	1.00
438_S	441_D	2.994	1.00
561_N	565_R	2.967	1.00
439_D	443_R	2.884	1.00
380_L	527_I	2.873	1.00
446_A	462_Y	2.855	1.00
351_Q	354_H	2.842	1.00
343_T	355_N	2.775	1.00
380_L	495_I	2.748	1.00
411_A	492_P	2.634	1.00
338_A	395_T	2.557	1.00
550_M	560_A	2.545	1.00
444_R	448_Q	2.506	1.00
430_I	446_A	2.464	1.00
336_T	361_R	2.426	1.00
443_R	452_H	2.423	1.00
360_L	366_M	2.404	1.00
490_D	522_K	2.396	1.00
385_G	388_K	2.395	1.00
345_S	351_Q	2.370	1.00
413_A	491_T	2.364	1.00
541_V	551_E	2.354	1.00
553_T	556_E	2.328	1.00
150_I	154_F	2.309	1.00
44_S	275_T	2.308	1.00
550_M	562_E	2.291	1.00
427_L	442_V	2.276	1.00
550_M	561_N	2.258	1.00
343_T	351_Q	2.246	1.00
343_T	391_S	2.204	1.00
358_F	541_V	2.186	1.00
434_N	441_D	2.184	1.00
365_K	537_A	2.184	1.00
443_R	447_K	2.135	1.00
336_T	362_Q	2.122	1.00
460_D	464_T	2.117	1.00
544_E	563_R	2.078	1.00
451_L	454_Y	2.068	1.00
339_F	358_F	2.051	1.00
430_I	442_V	2.050	1.00
516_F	536_A	2.024	1.00
44_S	273_A	2.012	1.00
508_E	530_H	1.984	1.00
360_L	525_L	1.978	1.00
388_K	402_A	1.955	1.00
312_N	316_P	1.941	1.00
441_D	490_D	1.939	1.00
14_N	91_D	1.937	1.00
341_D	357_S	1.926	1.00
345_S	390_D	1.922	1.00
335_V	397_N	1.920	1.00
99_M	319_E	1.908	1.00
443_R	456_E	1.899	1.00
10_Y	95_R	1.895	1.00
552_G	556_E	1.889	1.00
12_K	15_A	1.886	1.00
192_G	229_D	1.857	1.00
156_S	266_Q	1.837	1.00
57_Y	61_V	1.826	1.00
366_M	539_K	1.812	1.00
431_R	442_V	1.810	1.00
431_R	439_D	1.788	1.00
366_M	541_V	1.765	1.00
509_R	513_E	1.763	1.00
444_R	447_K	1.752	1.00
445_A	449_V	1.743	1.00
379_S	543_L	1.723	1.00
549_E	563_R	1.721	1.00
541_V	548_T	1.706	1.00
439_D	463_H	1.696	1.00
503_L	511_L	1.679	1.00
367_A	537_A	1.675	1.00
450_K	510_E	1.662	1.00
215_R	218_A	1.654	1.00
337_L	525_L	1.639	1.00
544_E	549_E	1.636	1.00
364_E	538_D	1.630	1.00
448_Q	517_E	1.626	1.00
467_Q	472_R	1.621	1.00
365_K	526_W	1.620	1.00
123_D	310_R	1.619	1.00
446_A	455_I	1.606	1.00
558_L	568_Y	1.605	1.00
61_V	65_T	1.604	1.00
430_I	488_L	1.599	1.00
334_D	397_N	1.595	1.00
437_A	488_L	1.583	1.00
400_E	403_L	1.580	1.00
466_V	473_F	1.568	1.00
187_A	309_R	1.559	1.00
368_L	541_V	1.542	1.00
550_M	565_R	1.540	1.00
336_T	397_N	1.531	1.00
453_D	456_E	1.528	1.00
368_L	379_S	1.525	1.00
443_R	462_Y	1.525	1.00
353_L	356_F	1.509	1.00
441_D	444_R	1.508	1.00
556_E	560_A	1.507	1.00
102_P	319_E	1.496	1.00
535_E	555_E	1.491	1.00
528_T	533_G	1.475	1.00
40_G	279_A	1.462	1.00
361_R	539_K	1.442	1.00
440_E	443_R	1.436	1.00
99_M	103_G	1.434	1.00
195_V	229_D	1.432	1.00
344_F	378_T	1.421	1.00
460_D	465_S	1.419	1.00
446_A	452_H	1.416	1.00
58_V	62_A	1.412	1.00
384_E	414_V	1.410	1.00
199_R	226_E	1.408	1.00
261_F	265_G	1.405	1.00
382_L	394_V	1.405	1.00
431_R	437_A	1.398	1.00
153_G	160_A	1.394	1.00
265_G	269_D	1.384	1.00
371_R	544_E	1.377	1.00
342_V	389_P	1.370	1.00
439_D	442_V	1.366	1.00
563_R	566_R	1.362	1.00
339_F	383_I	1.355	1.00
36_M	283_V	1.349	1.00
454_Y	477_E	1.349	1.00
513_E	517_E	1.348	1.00
355_N	547_K	1.347	1.00
441_D	488_L	1.345	1.00
180_L	183_R	1.341	1.00
333_Q	397_N	1.341	1.00
555_E	559_A	1.338	1.00
219_F	432_L	1.337	1.00
344_F	382_L	1.332	1.00
517_E	520_K	1.327	1.00
413_A	486_I	1.314	1.00
172_V	176_V	1.312	1.00
423_D	465_S	1.309	1.00
344_F	387_L	1.306	1.00
153_G	157_W	1.290	1.00
371_R	563_R	1.290	1.00
367_A	534_V	1.283	1.00
458_L	464_T	1.278	1.00
335_V	362_Q	1.277	1.00
188_K	233_L	1.273	1.00
192_G	233_L	1.261	1.00
426_I	481_I	1.254	1.00
192_G	195_V	1.254	1.00
13_Q	91_D	1.253	1.00
24_L	73_S	1.234	1.00
440_E	444_R	1.232	1.00
454_Y	458_L	1.230	1.00
434_N	437_A	1.223	1.00
372_S	507_T	1.222	1.00
340_R	357_S	1.219	1.00
343_T	354_H	1.217	1.00
467_Q	470_G	1.216	1.00
99_M	315_A	1.212	1.00
446_A	451_L	1.210	1.00
389_P	401_T	1.209	1.00
519_L	524_I	1.205	1.00
448_Q	487_L	1.205	1.00
399_V	403_L	1.204	1.00
383_I	525_L	1.203	1.00
266_Q	271_E	1.200	1.00
159_F	280_F	1.192	1.00
211_M	216_R	1.180	1.00
366_M	525_L	1.178	1.00
336_T	398_G	1.177	1.00
457_S	477_E	1.176	1.00
203_A	219_F	1.174	1.00
33_A	147_V	1.172	1.00
479_Q	501_V	1.171	1.00
451_L	455_I	1.169	1.00
273_A	276_M	1.163	1.00
362_Q	492_P	1.158	1.00
445_A	487_L	1.155	1.00
358_F	379_S	1.152	1.00
221_D	225_K	1.151	1.00
356_F	379_S	1.145	1.00
54_L	58_V	1.145	1.00
152_L	280_F	1.145	1.00
206_G	420_H	1.142	1.00
443_R	446_A	1.141	1.00
109_S	387_L	1.141	1.00
217_H	221_D	1.140	1.00
473_F	481_I	1.135	1.00
94_V	98_N	1.134	1.00
438_S	488_L	1.133	1.00
540_I	554_H	1.133	1.00
228_R	232_E	1.127	1.00
450_K	507_T	1.117	1.00
40_G	44_S	1.115	1.00
334_D	362_Q	1.114	1.00
399_V	404_L	1.112	1.00
96_L	314_V	1.107	1.00
456_E	461_G	1.105	1.00
351_Q	390_D	1.098	1.00
339_F	394_V	1.093	1.00
111_F	115_D	1.088	1.00
115_D	194_N	1.086	1.00
341_D	391_S	1.084	1.00
112_R	115_D	1.082	1.00
360_L	523_T	1.075	1.00
415_L	486_I	1.069	1.00
365_K	524_I	1.068	1.00
554_H	558_L	1.067	1.00
98_N	102_P	1.060	1.00
99_M	102_P	1.059	1.00
195_V	226_E	1.058	1.00
27_V	73_S	1.057	1.00
528_T	534_V	1.057	1.00
308_I	312_N	1.056	1.00
453_D	457_S	1.054	1.00
449_V	484_A	1.052	1.00
339_F	379_S	1.047	1.00
37_F	41_F	1.046	1.00
486_I	494_I	1.039	1.00
83_H	87_K	1.038	1.00
324_E	327_D	1.036	1.00
109_S	381_A	1.030	1.00
157_W	161_I	1.028	1.00
262_W	266_Q	1.027	1.00
419_P	482_A	1.025	1.00
161_I	165_L	1.024	1.00
337_L	383_I	1.022	1.00
526_W	537_A	1.022	1.00
219_F	222_A	1.020	1.00
382_L	389_P	1.018	1.00
225_K	229_D	1.011	1.00
346_Y	352_V	1.011	1.00
542_F	563_R	1.011	1.00
450_K	513_E	1.010	1.00
158_P	271_E	1.009	1.00
263_T	277_I	1.009	1.00
428_N	431_R	1.009	1.00
407_Q	410_D	1.009	1.00
166_Y	255_L	1.008	1.00
91_D	95_R	1.006	1.00
236_K	239_R	1.006	1.00
492_P	522_K	1.004	1.00
223_Y	227_E	1.001	1.00
231_F	235_R	1.000	1.00
450_K	514_T	0.999	1.00
498_E	529_H	0.997	1.00
17_L	83_H	0.996	1.00
38_T	59_P	0.996	1.00
364_E	551_E	0.991	1.00
126_H	307_S	0.990	1.00
494_I	522_K	0.990	1.00
21_V	81_G	0.989	1.00
396_L	408_I	0.988	1.00
455_I	462_Y	0.988	1.00
394_V	401_T	0.987	1.00
199_R	222_A	0.987	1.00
338_A	398_G	0.983	1.00
475_G	480_R	0.982	1.00
176_V	180_L	0.976	1.00
15_A	19_V	0.974	1.00
41_F	45_K	0.973	1.00
351_Q	391_S	0.972	1.00
24_L	76_V	0.971	1.00
215_R	219_F	0.970	1.00
442_V	462_Y	0.970	1.00
40_G	276_M	0.969	1.00
324_E	403_L	0.968	1.00
372_S	480_R	0.968	1.00
19_V	23_F	0.967	1.00
444_R	490_D	0.964	1.00
437_A	441_D	0.963	1.00
210_W	219_F	0.961	1.00
184_A	236_K	0.960	1.00
377_S	381_A	0.959	1.00
460_D	463_H	0.958	1.00
450_K	517_E	0.956	1.00
146_A	150_I	0.956	1.00
342_V	382_L	0.955	1.00
187_A	191_S	0.949	1.00
367_A	528_T	0.947	1.00
510_E	513_E	0.946	1.00
445_A	488_L	0.942	1.00
222_A	226_E	0.941	1.00
345_S	352_V	0.935	1.00
104_A	320_A	0.933	1.00
218_A	222_A	0.932	1.00
466_V	472_R	0.932	1.00
188_K	192_G	0.931	1.00
58_V	61_V	0.925	1.00
459_P	464_T	0.923	1.00
427_L	462_Y	0.920	1.00
543_L	548_T	0.919	1.00
404_L	408_I	0.917	1.00
24_L	80_V	0.916	1.00
355_N	391_S	0.915	1.00
90_S	94_V	0.914	1.00
448_Q	518_V	0.913	1.00
224_E	228_R	0.912	1.00
427_L	443_R	0.912	1.00
374_S	543_L	0.910	1.00
506_I	510_E	0.909	1.00
442_V	488_L	0.907	1.00
396_L	493_I	0.905	1.00
483_L	496_L	0.903	1.00
228_R	231_F	0.902	1.00
530_H	533_G	0.901	1.00
447_K	456_E	0.897	1.00
107_L	111_F	0.896	1.00
267_Q	272_L	0.894	1.00
229_D	233_L	0.893	1.00
95_R	99_M	0.892	1.00
119_I	313_N	0.892	1.00
338_A	357_S	0.890	1.00
384_E	495_I	0.890	1.00
123_D	307_S	0.888	1.00
305_Q	309_R	0.887	1.00
264_A	268_A	0.886	1.00
456_E	462_Y	0.886	1.00
65_T	69_A	0.885	1.00
337_L	396_L	0.884	1.00
500_T	511_L	0.884	1.00
415_L	483_L	0.884	1.00
556_E	559_A	0.883	1.00
389_P	402_A	0.882	1.00
96_L	120_L	0.882	1.00
407_Q	411_A	0.882	1.00
155_F	276_M	0.881	1.00
188_K	236_K	0.881	1.00
367_A	540_I	0.879	1.00
393_S	402_A	0.878	1.00
16_R	20_L	0.877	1.00
321_S	388_K	0.872	1.00
365_K	516_F	0.868	1.00
218_A	221_D	0.868	1.00
384_E	412_V	0.867	1.00
162_L	262_W	0.867	1.00
14_N	87_K	0.861	1.00
389_P	394_V	0.858	1.00
365_K	519_L	0.857	1.00
340_R	359_T	0.854	1.00
189_L	234_E	0.851	1.00
421_L	481_I	0.851	1.00
548_T	551_E	0.850	1.00
451_L	457_S	0.849	1.00
467_Q	471_I	0.846	1.00
208_S	381_A	0.845	1.00
106_M	320_A	0.843	1.00
152_L	160_A	0.842	1.00
332_L	397_N	0.842	1.00
422_F	429_N	0.838	1.00
347_D	350_S	0.836	1.00
401_T	408_I	0.836	1.00
406_D	410_D	0.834	1.00
222_A	225_K	0.834	1.00
180_L	184_A	0.830	1.00
466_V	470_G	0.830	1.00
345_S	348_N	0.830	1.00
562_E	565_R	0.829	1.00
330_L	404_L	0.829	1.00
430_I	481_I	0.828	1.00
220_I	224_E	0.827	1.00
421_L	478_R	0.824	1.00
448_Q	452_H	0.823	1.00
362_Q	397_N	0.823	1.00
104_A	321_S	0.822	1.00
175_P	179_L	0.822	1.00
221_D	224_E	0.821	1.00
395_T	398_G	0.820	1.00
345_S	349_S	0.819	1.00
449_V	480_R	0.819	1.00
494_I	519_L	0.817	1.00
31_S	69_A	0.817	1.00
154_F	157_W	0.817	1.00
173_L	247_A	0.815	1.00
149_V	160_A	0.814	1.00
151_A	155_F	0.813	1.00
21_V	84_I	0.812	1.00
356_F	548_T	0.812	1.00
491_T	522_K	0.811	1.00
31_S	73_S	0.811	1.00
217_H	220_I	0.809	1.00
158_P	266_Q	0.809	1.00
103_G	317_Q	0.808	1.00
544_E	547_K	0.807	1.00
180_L	240_F	0.807	1.00
430_I	462_Y	0.805	1.00
425_S	428_N	0.805	1.00
106_M	110_R	0.804	1.00
209_D	213_S	0.802	1.00
226_E	229_D	0.802	1.00
328_Q	399_V	0.800	1.00
99_M	318_P	0.792	1.00
311_M	315_A	0.790	1.00
451_L	481_I	0.790	1.00
55_L	58_V	0.789	1.00
171_V	175_P	0.787	1.00
343_T	390_D	0.786	1.00
512_M	533_G	0.782	1.00
412_V	493_I	0.779	1.00
431_R	436_E	0.779	1.00
96_L	311_M	0.777	1.00
235_R	239_R	0.777	1.00
41_F	59_P	0.776	1.00
508_E	512_M	0.776	1.00
330_L	333_Q	0.776	1.00
494_I	524_I	0.774	1.00
233_L	236_K	0.773	1.00
115_D	119_I	0.772	1.00
410_D	489_Q	0.771	1.00
60_I	64_R	0.771	1.00
72_V	76_V	0.771	1.00
558_L	565_R	0.768	1.00
275_T	279_A	0.768	1.00
512_M	528_T	0.767	1.00
25_G	140_S	0.763	1.00
267_Q	277_I	0.762	1.00
404_L	407_Q	0.761	1.00
116_M	314_V	0.761	1.00
229_D	232_E	0.759	1.00
418_K	478_R	0.758	1.00
561_N	566_R	0.757	1.00
328_Q	403_L	0.757	1.00
335_V	523_T	0.757	1.00
31_S	66_F	0.755	1.00
41_F	44_S	0.754	1.00
458_L	473_F	0.754	1.00
37_F	40_G	0.753	1.00
156_S	160_A	0.753	1.00
130_A	304_Y	0.753	1.00
207_V	211_M	0.753	1.00
151_A	154_F	0.752	1.00
206_G	209_D	0.751	1.00
30_F	34_F	0.751	1.00
126_H	303_G	0.751	1.00
337_L	493_I	0.750	1.00
332_L	492_P	0.750	1.00
100_L	108_R	0.750	1.00
37_F	151_A	0.748	1.00
369_L	542_F	0.747	1.00
179_L	183_R	0.745	1.00
266_Q	269_D	0.743	1.00
184_A	233_L	0.742	1.00
326_G	330_L	0.741	1.00
61_V	64_R	0.740	1.00
554_H	568_Y	0.740	1.00
192_G	226_E	0.739	1.00
44_S	47_A	0.738	1.00
45_K	55_L	0.738	1.00
454_Y	457_S	0.737	1.00
318_P	322_Q	0.736	1.00
153_G	164_A	0.735	1.00
232_E	236_K	0.735	1.00
147_V	150_I	0.733	1.00
141_A	293_P	0.733	1.00
330_L	407_Q	0.731	1.00
17_L	87_K	0.730	1.00
130_A	301_V	0.730	1.00
75_Y	79_L	0.730	1.00
372_S	498_E	0.728	1.00
38_T	66_F	0.728	1.00
62_A	65_T	0.726	1.00
155_F	279_A	0.725	1.00
475_G	502_G	0.724	1.00
345_S	350_S	0.724	1.00
354_H	545_N	0.723	1.00
38_T	62_A	0.723	1.00
43_I	278_A	0.723	1.00
480_R	507_T	0.722	1.00
196_L	230_W	0.720	1.00
165_L	168_F	0.719	1.00
389_P	393_S	0.719	1.00
479_Q	502_G	0.715	1.00
138_A	142_L	0.714	1.00
321_S	385_G	0.714	1.00
119_I	123_D	0.713	1.00
250_C	254_G	0.712	1.00
9_P	95_R	0.712	1.00
363_G	523_T	0.705	1.00
500_T	508_E	0.705	1.00
350_S	354_H	0.703	1.00
142_L	146_A	0.703	1.00
17_L	80_V	0.702	1.00
95_R	98_N	0.702	1.00
434_N	489_Q	0.701	1.00
450_K	453_D	0.701	1.00
158_P	161_I	0.700	1.00
309_R	313_N	0.699	1.00
29_I	143_L	0.698	1.00
14_N	17_L	0.697	1.00
59_P	62_A	0.697	1.00
23_F	27_V	0.696	1.00
446_A	449_V	0.696	1.00
9_P	12_K	0.695	1.00
188_K	191_S	0.694	1.00
69_A	73_S	0.693	1.00
408_I	412_V	0.693	1.00
508_E	533_G	0.692	1.00
395_T	400_E	0.691	1.00
426_I	455_I	0.687	1.00
381_A	387_L	0.686	1.00
190_K	193_R	0.686	1.00
365_K	536_A	0.686	1.00
366_M	551_E	0.685	1.00
327_D	330_L	0.685	1.00
156_S	272_L	0.682	1.00
45_K	48_T	0.681	1.00
555_E	558_L	0.681	1.00
539_K	553_T	0.680	1.00
12_K	16_R	0.680	1.00
160_A	280_F	0.679	1.00
423_D	467_Q	0.679	1.00
560_A	563_R	0.678	1.00
329_I	407_Q	0.677	1.00
329_I	405_K	0.677	1.00
20_L	80_V	0.677	1.00
148_S	286_P	0.675	1.00
103_G	319_E	0.675	1.00
451_L	462_Y	0.675	1.00
434_N	490_D	0.673	1.00
360_L	364_E	0.672	1.00
550_M	563_R	0.671	1.00
439_D	462_Y	0.671	1.00
511_L	514_T	0.670	1.00
172_V	175_P	0.669	1.00
178_S	182_T	0.668	1.00
304_Y	307_S	0.667	1.00
448_Q	514_T	0.665	1.00
98_N	220_I	0.665	1.00
396_L	401_T	0.664	1.00
346_Y	378_T	0.663	1.00
184_A	188_K	0.663	1.00
27_V	69_A	0.663	1.00
431_R	434_N	0.662	1.00
159_F	266_Q	0.662	1.00
380_L	525_L	0.662	1.00
37_F	155_F	0.662	1.00
55_L	59_P	0.660	1.00
28_T	74_R	0.658	1.00
382_L	387_L	0.658	1.00
353_L	543_L	0.657	1.00
118_G	197_Y	0.657	1.00
443_R	455_I	0.654	1.00
150_I	153_G	0.654	1.00
148_S	287_L	0.653	1.00
92_M	124_I	0.651	1.00
89_V	93_R	0.651	1.00
163_L	284_V	0.649	1.00
327_D	407_Q	0.648	1.00
421_L	466_V	0.648	1.00
363_G	521_G	0.647	1.00
483_L	487_L	0.645	1.00
105_L	109_S	0.645	1.00
123_D	190_K	0.645	1.00
89_V	128_Q	0.645	1.00
368_L	525_L	0.643	1.00
441_D	445_A	0.643	1.00
445_A	484_A	0.642	1.00
334_D	523_T	0.642	1.00
96_L	315_A	0.642	1.00
112_R	198_S	0.641	1.00
495_I	525_L	0.640	1.00
33_A	36_M	0.640	1.00
44_S	48_T	0.639	1.00
439_D	446_A	0.639	1.00
339_F	356_F	0.637	1.00
95_R	315_A	0.636	1.00
344_F	352_V	0.636	1.00
127_L	308_I	0.636	1.00
483_L	511_L	0.635	1.00
474_S	477_E	0.635	1.00
461_G	464_T	0.634	1.00
550_M	558_L	0.633	1.00
238_Q	242_R	0.632	1.00
539_K	556_E	0.632	1.00
183_R	188_K	0.631	1.00
140_S	144_L	0.630	1.00
194_N	310_R	0.630	1.00
424_T	465_S	0.630	1.00
534_V	537_A	0.629	1.00
550_M	557_L	0.627	1.00
397_N	492_P	0.625	1.00
266_Q	270_G	0.625	1.00
289_E	293_P	0.625	1.00
25_G	77_E	0.624	1.00
156_S	159_F	0.623	1.00
249_Q	292_L	0.623	1.00
57_Y	60_I	0.622	1.00
348_N	390_D	0.622	1.00
90_S	227_E	0.621	1.00
129_D	300_E	0.621	1.00
425_S	463_H	0.620	1.00
418_K	469_T	0.619	1.00
380_L	414_V	0.617	1.00
82_H	133_K	0.616	1.00
87_K	90_S	0.616	1.00
99_M	317_Q	0.615	1.00
68_I	72_V	0.614	1.00
262_W	265_G	0.614	1.00
514_T	517_E	0.614	1.00
333_Q	411_A	0.612	1.00
423_D	472_R	0.612	1.00
505_P	508_E	0.610	1.00
508_E	532_A	0.610	1.00
563_R	567_L	0.607	1.00
431_R	446_A	0.607	1.00
413_A	489_Q	0.607	1.00
503_L	507_T	0.606	1.00
148_S	283_V	0.606	1.00
442_V	446_A	0.605	1.00
96_L	124_I	0.604	1.00
356_F	543_L	0.604	1.00
551_E	556_E	0.604	1.00
107_L	116_M	0.604	1.00
328_Q	331_D	0.603	1.00
444_R	518_V	0.603	1.00
560_A	565_R	0.600	1.00
254_G	258_L	0.600	1.00
125_E	128_Q	0.599	1.00
358_F	548_T	0.599	1.00
480_R	503_L	0.598	1.00
554_H	557_L	0.598	1.00
54_L	57_Y	0.598	1.00
115_D	310_R	0.598	1.00
350_S	545_N	0.597	1.00
513_E	536_A	0.597	1.00
236_K	240_F	0.597	1.00
360_L	365_K	0.596	1.00
104_A	107_L	0.596	1.00
342_V	392_G	0.596	1.00
345_S	391_S	0.594	1.00
550_M	566_R	0.592	1.00
449_V	483_L	0.592	1.00
50_P	53_I	0.591	1.00
449_V	487_L	0.590	1.00
186_N	237_K	0.589	1.00
320_A	409_A	0.588	1.00
92_M	127_L	0.588	1.00
192_G	230_W	0.587	1.00
493_I	523_T	0.586	1.00
85_I	132_L	0.586	1.00
476_G	504_D	0.584	1.00
504_D	507_T	0.584	1.00
209_D	212_F	0.584	1.00
34_F	66_F	0.583	1.00
512_M	526_W	0.583	1.00
513_E	516_F	0.582	1.00
415_L	496_L	0.580	1.00
14_N	88_I	0.578	1.00
361_R	366_M	0.577	1.00
258_L	262_W	0.577	1.00
447_K	453_D	0.577	1.00
342_V	357_S	0.576	1.00
190_K	306_D	0.575	1.00
549_E	561_N	0.575	1.00
97_Y	101_E	0.575	1.00
322_Q	405_K	0.574	1.00
349_S	352_V	0.573	1.00
450_K	511_L	0.573	1.00
176_V	179_L	0.573	1.00
188_K	229_D	0.572	1.00
272_L	276_M	0.572	1.00
356_F	541_V	0.572	1.00
16_R	19_V	0.571	1.00
342_V	394_V	0.570	1.00
118_G	194_N	0.569	1.00
416_N	419_P	0.569	1.00
396_L	404_L	0.569	1.00
335_V	492_P	0.568	1.00
82_H	86_L	0.567	1.00
372_S	528_T	0.567	1.00
264_A	267_Q	0.566	1.00
307_S	310_R	0.566	1.00
512_M	536_A	0.565	1.00
232_E	235_R	0.564	1.00
545_N	549_E	0.561	1.00
129_D	133_K	0.561	1.00
199_R	203_A	0.561	1.00
105_L	386_A	0.560	1.00
327_D	405_K	0.560	1.00
27_V	31_S	0.560	1.00
62_A	66_F	0.559	1.00
141_A	145_Y	0.558	1.00
118_G	193_R	0.557	1.00
351_Q	355_N	0.557	1.00
145_Y	149_V	0.556	1.00
86_L	89_V	0.556	1.00
37_F	279_A	0.556	1.00
417_Q	475_G	0.554	1.00
542_F	550_M	0.552	1.00
124_I	311_M	0.552	1.00
487_L	518_V	0.552	1.00
447_K	462_Y	0.552	1.00
535_E	554_H	0.551	1.00
381_A	414_V	0.550	1.00
326_G	403_L	0.549	1.00
191_S	195_V	0.549	1.00
137_P	293_P	0.549	1.00
540_I	553_T	0.549	1.00
141_A	144_L	0.548	1.00
263_T	267_Q	0.548	1.00
40_G	275_T	0.548	1.00
110_R	347_D	0.548	1.00
79_L	83_H	0.547	1.00
158_P	262_W	0.545	1.00
178_S	181_V	0.545	1.00
429_N	481_I	0.544	1.00
431_R	488_L	0.544	1.00
189_L	237_K	0.544	1.00
455_I	458_L	0.544	1.00
154_F	158_P	0.543	1.00
118_G	122_E	0.542	1.00
28_T	73_S	0.542	1.00
199_R	219_F	0.542	1.00
140_S	143_L	0.542	1.00
324_E	328_Q	0.540	1.00
442_V	445_A	0.540	1.00
558_L	561_N	0.540	1.00
564_Y	567_L	0.539	1.00
354_H	357_S	0.539	1.00
389_P	400_E	0.538	1.00
333_Q	362_Q	0.538	1.00
348_N	351_Q	0.538	1.00
377_S	380_L	0.536	1.00
71_S	75_Y	0.536	1.00
64_R	68_I	0.536	1.00
519_L	522_K	0.535	1.00
13_Q	95_R	0.534	1.00
119_I	310_R	0.533	1.00
372_S	503_L	0.533	1.00
369_L	534_V	0.533	1.00
272_L	277_I	0.532	1.00
452_H	455_I	0.532	1.00
253_A	257_L	0.532	1.00
89_V	124_I	0.532	1.00
17_L	84_I	0.531	1.00
430_I	433_G	0.531	1.00
177_V	244_R	0.531	1.00
113_T	117_L	0.531	1.00
544_E	566_R	0.530	1.00
101_E	104_A	0.530	1.00
405_K	408_I	0.530	1.00
434_N	438_S	0.529	1.00
193_R	197_Y	0.529	1.00
426_I	466_V	0.528	1.00
38_T	41_F	0.528	1.00
343_T	353_L	0.526	1.00
499_P	528_T	0.524	1.00
46_A	55_L	0.524	1.00
73_S	76_V	0.524	1.00
169_V	172_V	0.523	1.00
368_L	527_I	0.523	1.00
127_L	311_M	0.523	1.00
157_W	160_A	0.523	1.00
361_R	523_T	0.522	1.00
230_W	234_E	0.522	1.00
169_V	173_L	0.521	1.00
399_V	407_Q	0.520	1.00
14_N	84_I	0.519	1.00
455_I	461_G	0.519	1.00
51_E	55_L	0.519	1.00
507_T	511_L	0.519	1.00
114_G	198_S	0.518	1.00
13_Q	16_R	0.518	1.00
332_L	335_V	0.518	1.00
19_V	22_I	0.517	1.00
76_V	80_V	0.516	1.00
378_T	387_L	0.516	1.00
40_G	155_F	0.516	1.00
325_S	329_I	0.514	1.00
359_T	551_E	0.514	1.00
370_G	376_K	0.514	1.00
487_L	514_T	0.514	1.00
365_K	521_G	0.514	1.00
333_Q	396_L	0.514	1.00
505_P	532_A	0.513	1.00
525_L	541_V	0.513	1.00
122_E	190_K	0.512	1.00
564_Y	568_Y	0.512	1.00
242_R	246_F	0.512	1.00
195_V	199_R	0.512	1.00
268_A	271_E	0.511	1.00
368_L	543_L	0.511	1.00
415_L	499_P	0.511	1.00
378_T	382_L	0.510	1.00
326_G	405_K	0.510	1.00
108_R	111_F	0.509	1.00
32_A	70_R	0.509	1.00
385_G	401_T	0.508	1.00
29_I	32_A	0.508	1.00
149_V	153_G	0.507	1.00
425_S	465_S	0.507	1.00
120_L	124_I	0.506	1.00
476_G	480_R	0.506	1.00
47_A	50_P	0.506	1.00
360_L	541_V	0.506	1.00
122_E	125_E	0.506	1.00
79_L	82_H	0.506	1.00
526_W	534_V	0.506	1.00
225_K	228_R	0.506	1.00
514_T	518_V	0.505	1.00
339_F	382_L	0.505	1.00
164_A	168_F	0.505	1.00
480_R	502_G	0.505	1.00
196_L	200_L	0.504	1.00
426_I	451_L	0.503	1.00
500_T	503_L	0.503	1.00
496_L	499_P	0.502	1.00
446_A	484_A	0.502	1.00
276_M	279_A	0.502	1.00
25_G	29_I	0.501	1.00
141_A	294_L	0.501	1.00
183_R	187_A	0.501	1.00
283_V	290_A	0.501	1.00
493_I	525_L	0.501	1.00
499_P	526_W	0.501	1.00
542_F	549_E	0.500	1.00
328_Q	332_L	0.500	1.00
518_V	521_G	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4ry2A	2	0.9722	100	0.071	Contact Map
4a82A	2	0.9913	100	0.102	Contact Map
4q4hB	1	0.9913	100	0.135	Contact Map
4f4cA	1	0.9739	100	0.141	Contact Map
3b5xA	2	0.9896	100	0.148	Contact Map
3b60A	2	0.9896	100	0.151	Contact Map
4q4hA	1	0.9896	100	0.152	Contact Map
3zdqA	2	0.9687	100	0.156	Contact Map
4mrsA	2	0.9983	100	0.156	Contact Map
4q9hA	1	0.993	100	0.163	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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