CYDC - BACSU - GREMLIN Contacts

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CYDC - ATP-binding/permease protein CydC

UniProt:	P94366	Sequences: MGKDLFRYKGMKRILTLITCLTLIQTAAIIMQAEWLSEAVTGLFNGKGITSLLPVIGFFLIAFIARHGMTVARQKIVYQYAARTGADLRKSFLDQLFRLGPRFAKKEGTGQMVTLAMEGISQFRRYLELFLPKMVSMAIVPAAVVIYVFFQDRTSAIILVAAMPILIIFMILLGLVAQRKADRQWKSYQRLSNHFVDSLRGLETLRFLGLSKSHSKNIFYVSERYRKATMSTLRVAFLSSFALDFFTMLSVATVAVFLGLRLIDGDILLGPALTALILAPEYFLPVREVGNDYHATLNGQEAGKTIQEILSQPGFKEETPLQLEAWSDQDELKLSGVSVGRSVSDIHLSFKGKKKIGIIGASGAGKSTLIDILGGFLEPDGGMIEVNGTSRSHLQDGSWQKNLLYIPQHPYIFDDTLGNNIRFYHPSASAEDTTRAAASAGLTELVNNLPDGLEGRIGEGGRALSGGQAQRVALARAFLGNRPILLLDEPTAHLDIETEYEIKETMLDLFEDKLVFLATHRLHWMLDMDEIIVLDGGRVAEIGTHNELLEKNGVYTKLVKAQLGERA	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	567 (549)
Sequences:	52214 (37106)
Seq/√Len:	1583.7

ECOLI - MDLA MSBA MDLB CYDD CYDC YOJI YDDA
BACSU - CYDC YHEH YFIC YWJA YKNU YGAD YKNV BMRA YHEI CYDD YFIB SUNT YVRA OPUAA OPUCA
HALSA - Q9HSQ7 Q9HMX3 Q9HMW0 BTUDA
SULSO - Q97UJ9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
443_T	453_L	4.540	1.00
336_G	345_D	4.525	1.00
354_K	530_E	4.459	1.00
333_K	349_S	4.325	1.00
351_K	354_K	4.286	1.00
335_S	383_M	3.966	1.00
415_D	419_N	3.958	1.00
530_E	542_I	3.846	1.00
418_G	430_A	3.751	1.00
438_A	443_T	3.693	1.00
545_H	555_Y	3.691	1.00
383_M	390_S	3.374	1.00
443_T	447_N	3.367	1.00
335_S	385_E	3.367	1.00
331_E	349_S	3.281	1.00
344_S	538_R	3.180	1.00
334_L	337_V	3.175	1.00
418_G	454_E	3.015	1.00
429_S	432_D	3.005	1.00
418_G	422_R	2.958	1.00
552_N	556_T	2.943	1.00
370_I	518_A	2.921	1.00
338_S	345_D	2.883	1.00
437_A	453_L	2.872	1.00
430_A	434_T	2.799	1.00
370_I	486_L	2.704	1.00
402_N	483_P	2.547	1.00
421_I	437_A	2.511	1.00
435_R	439_S	2.507	1.00
541_E	551_K	2.492	1.00
333_K	385_E	2.471	1.00
331_E	351_K	2.448	1.00
350_F	356_I	2.422	1.00
404_L	482_R	2.401	1.00
434_T	443_T	2.394	1.00
425_H	432_D	2.388	1.00
375_G	378_E	2.373	1.00
451_D	455_G	2.370	1.00
146_I	150_F	2.341	1.00
481_N	513_K	2.340	1.00
41_T	270_G	2.318	1.00
532_I	542_I	2.295	1.00
544_T	547_E	2.286	1.00
541_E	553_G	2.286	1.00
395_Q	398_S	2.266	1.00
348_L	532_I	2.264	1.00
541_E	552_N	2.235	1.00
418_G	433_T	2.205	1.00
434_T	438_A	2.197	1.00
331_E	352_G	2.175	1.00
355_K	528_M	2.158	1.00
41_T	268_L	2.153	1.00
334_L	348_L	2.107	1.00
338_S	381_G	2.107	1.00
421_I	433_T	2.090	1.00
442_L	445_L	2.081	1.00
330_D	387_N	2.060	1.00
336_G	347_H	2.009	1.00
535_D	554_V	1.972	1.00
507_L	527_D	1.972	1.00
350_F	516_F	1.969	1.00
340_G	380_D	1.942	1.00
499_E	521_R	1.937	1.00
378_E	392_S	1.930	1.00
307_Q	311_S	1.928	1.00
11_M	87_D	1.916	1.00
432_D	481_N	1.906	1.00
434_T	447_N	1.882	1.00
95_Q	314_G	1.874	1.00
152_D	261_R	1.864	1.00
356_I	530_E	1.858	1.00
435_R	438_A	1.838	1.00
543_G	547_E	1.828	1.00
422_R	433_T	1.820	1.00
53_L	57_G	1.802	1.00
436_A	440_A	1.800	1.00
187_S	224_R	1.796	1.00
422_R	430_A	1.741	1.00
500_Y	504_E	1.728	1.00
356_I	532_I	1.723	1.00
369_L	534_L	1.714	1.00
57_G	61_I	1.710	1.00
494_L	502_I	1.700	1.00
532_I	539_V	1.686	1.00
329_Q	387_N	1.659	1.00
332_L	516_F	1.656	1.00
540_A	554_V	1.650	1.00
390_S	393_H	1.650	1.00
357_G	528_M	1.648	1.00
343_V	346_I	1.637	1.00
437_A	446_V	1.636	1.00
182_D	304_K	1.628	1.00
430_A	454_E	1.622	1.00
439_S	508_D	1.609	1.00
441_G	501_E	1.603	1.00
119_G	305_T	1.598	1.00
358_I	369_L	1.597	1.00
444_E	447_N	1.592	1.00
210_L	213_S	1.589	1.00
535_D	540_A	1.587	1.00
354_K	529_D	1.585	1.00
421_I	479_L	1.578	1.00
458_G	463_A	1.565	1.00
355_K	517_L	1.552	1.00
434_T	453_L	1.546	1.00
457_I	464_L	1.536	1.00
331_E	387_N	1.526	1.00
541_E	556_T	1.522	1.00
526_L	546_N	1.519	1.00
547_E	551_K	1.513	1.00
358_I	532_I	1.503	1.00
519_T	524_W	1.491	1.00
95_Q	99_L	1.472	1.00
431_E	434_T	1.471	1.00
432_D	435_R	1.471	1.00
345_D	538_R	1.459	1.00
37_S	274_T	1.458	1.00
372_I	384_I	1.445	1.00
351_K	530_E	1.444	1.00
437_A	443_T	1.444	1.00
190_R	224_R	1.436	1.00
98_R	314_G	1.434	1.00
149_F	156_A	1.428	1.00
428_A	479_L	1.427	1.00
339_V	368_T	1.425	1.00
260_L	264_D	1.419	1.00
451_D	456_R	1.408	1.00
508_D	511_E	1.407	1.00
256_V	260_L	1.405	1.00
430_A	433_T	1.405	1.00
374_G	405_Y	1.386	1.00
328_D	387_N	1.364	1.00
54_P	58_F	1.350	1.00
361_A	535_D	1.348	1.00
504_E	508_D	1.342	1.00
194_H	221_V	1.337	1.00
425_H	428_A	1.333	1.00
546_N	550_E	1.332	1.00
432_D	479_L	1.331	1.00
445_L	468_Q	1.319	1.00
339_V	377_L	1.318	1.00
339_V	372_I	1.316	1.00
404_L	477_A	1.315	1.00
334_L	373_L	1.314	1.00
33_A	278_L	1.313	1.00
149_F	153_R	1.311	1.00
458_G	461_G	1.310	1.00
554_V	557_K	1.309	1.00
361_A	554_V	1.303	1.00
95_Q	310_L	1.302	1.00
414_D	456_R	1.301	1.00
337_V	379_P	1.296	1.00
417_L	472_V	1.296	1.00
214_H	423_F	1.291	1.00
330_D	352_G	1.279	1.00
357_G	525_M	1.271	1.00
379_P	391_R	1.271	1.00
176_V	179_R	1.265	1.00
183_R	228_A	1.259	1.00
21_L	69_M	1.254	1.00
422_R	428_A	1.253	1.00
319_T	322_Q	1.249	1.00
362_S	498_T	1.246	1.00
335_S	347_H	1.244	1.00
449_L	455_G	1.239	1.00
437_A	442_L	1.234	1.00
331_E	388_G	1.223	1.00
356_I	516_F	1.213	1.00
373_L	516_F	1.212	1.00
155_S	275_A	1.209	1.00
187_S	228_A	1.205	1.00
10_G	87_D	1.203	1.00
30_I	143_A	1.194	1.00
261_R	266_D	1.191	1.00
168_I	172_L	1.190	1.00
206_R	211_S	1.188	1.00
431_E	435_R	1.185	1.00
338_S	344_S	1.182	1.00
436_A	478_F	1.178	1.00
531_I	545_H	1.176	1.00
429_S	479_L	1.175	1.00
105_K	377_L	1.174	1.00
439_S	478_F	1.173	1.00
448_N	468_Q	1.173	1.00
510_F	515_V	1.172	1.00
389_T	393_H	1.166	1.00
336_G	381_G	1.164	1.00
442_L	446_V	1.164	1.00
148_V	275_A	1.162	1.00
216_K	220_Y	1.160	1.00
445_L	449_L	1.155	1.00
346_I	369_L	1.154	1.00
187_S	190_R	1.153	1.00
434_T	437_A	1.150	1.00
352_G	483_P	1.149	1.00
201_G	411_Y	1.144	1.00
464_L	472_V	1.142	1.00
396_D	400_Q	1.141	1.00
198_S	214_H	1.137	1.00
268_L	271_P	1.133	1.00
212_K	216_K	1.132	1.00
348_L	369_L	1.125	1.00
350_F	514_L	1.123	1.00
470_Q	492_A	1.121	1.00
329_Q	352_G	1.110	1.00
389_T	394_L	1.104	1.00
24_I	69_M	1.100	1.00
92_F	309_I	1.098	1.00
545_H	549_L	1.098	1.00
441_G	498_T	1.098	1.00
90_K	94_D	1.096	1.00
223_E	227_K	1.092	1.00
447_N	452_G	1.082	1.00
466_G	471_R	1.076	1.00
519_T	525_M	1.075	1.00
355_K	515_V	1.072	1.00
107_E	111_Q	1.070	1.00
446_V	453_L	1.068	1.00
334_L	384_I	1.066	1.00
111_Q	189_Q	1.060	1.00
37_S	41_T	1.057	1.00
332_L	373_L	1.057	1.00
384_I	391_R	1.053	1.00
154_T	266_D	1.053	1.00
108_G	111_Q	1.052	1.00
303_G	307_Q	1.052	1.00
16_T	20_C	1.051	1.00
105_K	371_D	1.051	1.00
50_T	54_P	1.049	1.00
406_I	477_A	1.048	1.00
48_G	51_S	1.046	1.00
258_L	272_A	1.045	1.00
372_I	379_P	1.037	1.00
334_L	369_L	1.033	1.00
34_E	38_E	1.031	1.00
95_Q	98_R	1.031	1.00
444_E	448_N	1.031	1.00
94_D	98_R	1.027	1.00
162_A	250_S	1.026	1.00
157_I	161_A	1.026	1.00
477_A	485_L	1.025	1.00
214_H	217_N	1.022	1.00
79_Q	83_R	1.017	1.00
180_K	231_S	1.016	1.00
218_I	222_S	1.014	1.00
398_S	401_K	1.013	1.00
440_A	475_A	1.011	1.00
354_K	542_I	1.011	1.00
332_L	386_V	1.009	1.00
441_G	505_T	1.008	1.00
35_W	55_V	1.008	1.00
231_S	234_R	1.007	1.00
21_L	72_A	1.006	1.00
333_K	388_G	1.006	1.00
190_R	221_V	1.006	1.00
257_F	261_R	1.002	1.00
153_R	157_I	1.001	1.00
483_P	513_K	0.995	1.00
220_Y	224_R	0.995	1.00
489_E	520_H	0.994	1.00
362_S	471_R	0.992	1.00
441_G	504_E	0.991	1.00
419_N	422_R	0.991	1.00
485_L	513_K	0.990	1.00
410_P	473_A	0.988	1.00
451_D	454_E	0.986	1.00
142_A	146_I	0.984	1.00
122_Q	302_A	0.981	1.00
418_G	453_L	0.980	1.00
226_R	230_M	0.978	1.00
553_G	556_T	0.977	1.00
517_L	528_M	0.977	1.00
435_R	481_N	0.976	1.00
367_S	371_D	0.973	1.00
386_V	399_W	0.972	1.00
533_V	554_V	0.972	1.00
534_L	539_V	0.970	1.00
386_V	484_I	0.966	1.00
14_I	79_Q	0.964	1.00
333_K	347_H	0.963	1.00
319_T	393_H	0.963	1.00
194_H	217_N	0.963	1.00
428_A	432_D	0.961	1.00
521_R	524_W	0.956	1.00
205_L	214_H	0.956	1.00
318_E	395_Q	0.956	1.00
12_K	16_T	0.956	1.00
18_I	77_V	0.955	1.00
474_L	487_L	0.953	1.00
21_L	76_I	0.949	1.00
345_D	381_G	0.947	1.00
441_G	508_D	0.946	1.00
357_G	519_T	0.946	1.00
457_I	463_A	0.946	1.00
87_D	91_S	0.944	1.00
119_G	302_A	0.943	1.00
337_V	372_I	0.942	1.00
217_N	221_V	0.941	1.00
394_L	399_W	0.940	1.00
61_I	65_A	0.936	1.00
151_Q	271_P	0.935	1.00
13_R	17_L	0.935	1.00
100_G	315_F	0.934	1.00
436_A	479_L	0.932	1.00
37_S	271_P	0.932	1.00
433_T	453_L	0.930	1.00
262_L	267_I	0.928	1.00
501_E	504_E	0.926	1.00
421_I	472_V	0.925	1.00
115_L	308_E	0.924	1.00
418_G	434_T	0.922	1.00
447_N	453_L	0.921	1.00
172_L	176_V	0.918	1.00
176_V	235_V	0.909	1.00
213_S	217_N	0.907	1.00
210_L	214_H	0.907	1.00
364_A	534_L	0.906	1.00
158_I	257_F	0.905	1.00
438_A	447_N	0.904	1.00
223_E	226_R	0.901	1.00
300_Q	304_K	0.898	1.00
406_I	474_L	0.897	1.00
169_F	242_A	0.896	1.00
91_S	95_Q	0.895	1.00
379_P	392_S	0.895	1.00
182_D	186_K	0.895	1.00
458_G	462_R	0.892	1.00
183_R	187_S	0.890	1.00
439_S	509_L	0.889	1.00
183_R	231_S	0.889	1.00
374_G	486_L	0.888	1.00
327_S	387_N	0.887	1.00
497_E	501_E	0.886	1.00
54_P	57_G	0.885	1.00
383_M	392_S	0.880	1.00
180_K	228_A	0.879	1.00
491_T	502_I	0.879	1.00
38_E	42_G	0.878	1.00
547_E	550_E	0.877	1.00
219_F	223_E	0.875	1.00
28_A	65_A	0.875	1.00
422_R	427_S	0.875	1.00
259_G	263_I	0.873	1.00
539_V	542_I	0.872	1.00
103_F	107_E	0.871	1.00
346_I	539_V	0.870	1.00
442_L	448_N	0.870	1.00
355_K	510_F	0.870	1.00
86_A	90_K	0.869	1.00
92_F	116_A	0.866	1.00
379_P	384_I	0.865	1.00
374_G	403_L	0.864	1.00
433_T	479_L	0.862	1.00
375_G	396_D	0.862	1.00
412_I	472_V	0.861	1.00
224_R	228_A	0.860	1.00
323_L	389_T	0.860	1.00
357_G	531_I	0.858	1.00
398_S	402_N	0.855	1.00
457_I	461_G	0.855	1.00
323_L	393_H	0.846	1.00
355_K	507_L	0.845	1.00
391_R	399_W	0.843	1.00
145_V	156_A	0.843	1.00
397_G	401_K	0.842	1.00
503_K	519_T	0.842	1.00
338_S	380_D	0.839	1.00
100_G	316_K	0.836	1.00
535_D	538_R	0.833	1.00
167_I	171_I	0.830	1.00
416_T	419_N	0.829	1.00
216_K	219_F	0.829	1.00
95_Q	313_P	0.828	1.00
352_G	387_N	0.827	1.00
325_A	394_L	0.825	1.00
261_R	264_D	0.823	1.00
184_Q	229_T	0.822	1.00
213_S	216_K	0.822	1.00
18_I	80_Y	0.820	1.00
482_R	513_K	0.819	1.00
176_V	180_K	0.819	1.00
332_L	484_I	0.819	1.00
412_I	469_A	0.817	1.00
440_A	471_R	0.816	1.00
552_N	557_K	0.815	1.00
203_E	371_D	0.815	1.00
306_I	310_L	0.814	1.00
28_A	69_M	0.814	1.00
485_L	510_F	0.812	1.00
148_V	156_A	0.811	1.00
204_T	208_L	0.810	1.00
24_I	65_A	0.809	1.00
92_F	306_I	0.808	1.00
112_M	309_I	0.805	1.00
217_N	220_Y	0.804	1.00
147_Y	151_Q	0.803	1.00
68_G	72_A	0.802	1.00
549_L	556_T	0.802	1.00
56_I	60_L	0.798	1.00
485_L	515_V	0.797	1.00
385_E	388_G	0.796	1.00
439_S	443_T	0.795	1.00
403_L	484_I	0.794	1.00
35_W	62_A	0.793	1.00
11_M	83_R	0.793	1.00
553_G	558_L	0.791	1.00
99_L	312_Q	0.790	1.00
41_T	44_F	0.787	1.00
221_V	224_R	0.786	1.00
171_I	175_L	0.785	1.00
325_A	328_D	0.785	1.00
215_S	219_F	0.784	1.00
322_Q	398_S	0.784	1.00
421_I	453_L	0.783	1.00
470_Q	493_H	0.783	1.00
379_P	383_M	0.782	1.00
442_L	472_V	0.781	1.00
394_L	398_S	0.781	1.00
316_K	378_E	0.781	1.00
102_R	106_K	0.780	1.00
324_E	398_S	0.780	1.00
335_S	349_S	0.780	1.00
359_I	533_V	0.777	1.00
330_D	514_L	0.776	1.00
35_W	58_F	0.776	1.00
179_R	183_R	0.776	1.00
503_K	524_W	0.774	1.00
422_R	425_H	0.773	1.00
262_L	272_A	0.772	1.00
152_D	156_A	0.772	1.00
318_E	322_Q	0.772	1.00
126_Y	299_G	0.772	1.00
499_E	503_K	0.771	1.00
102_R	315_F	0.771	1.00
150_F	153_R	0.770	1.00
111_Q	115_L	0.769	1.00
437_A	440_A	0.768	1.00
202_L	206_R	0.766	1.00
430_A	453_L	0.765	1.00
401_K	480_G	0.765	1.00
212_K	215_S	0.765	1.00
28_A	62_A	0.764	1.00
38_E	41_T	0.764	1.00
201_G	204_T	0.764	1.00
38_E	55_V	0.764	1.00
228_A	231_S	0.763	1.00
450_P	455_G	0.760	1.00
20_C	24_I	0.760	1.00
161_A	164_P	0.758	1.00
58_F	61_I	0.757	1.00
96_L	104_A	0.757	1.00
154_T	261_R	0.756	1.00
27_A	31_M	0.755	1.00
126_Y	296_T	0.755	1.00
325_A	398_S	0.754	1.00
154_T	157_I	0.752	1.00
34_E	147_Y	0.751	1.00
143_A	146_I	0.751	1.00
65_A	69_M	0.750	1.00
413_F	420_N	0.749	1.00
187_S	221_V	0.748	1.00
362_S	489_E	0.748	1.00
466_G	493_H	0.747	1.00
318_E	321_L	0.747	1.00
318_E	396_D	0.743	1.00
191_L	225_Y	0.741	1.00
270_G	274_T	0.741	1.00
55_V	58_F	0.741	1.00
51_S	54_P	0.740	1.00
409_H	469_A	0.739	1.00
422_R	426_P	0.739	1.00
227_K	231_S	0.738	1.00
344_S	536_G	0.737	1.00
546_N	549_L	0.737	1.00
122_Q	298_N	0.735	1.00
343_V	534_L	0.735	1.00
327_S	483_P	0.734	1.00
230_M	234_R	0.733	1.00
442_L	453_L	0.731	1.00
224_R	227_K	0.730	1.00
353_K	512_D	0.730	1.00
34_E	37_S	0.726	1.00
445_L	448_N	0.726	1.00
156_A	275_A	0.726	1.00
71_V	75_K	0.724	1.00
147_Y	150_F	0.724	1.00
26_T	139_I	0.722	1.00
138_A	142_A	0.720	1.00
22_T	136_S	0.720	1.00
57_G	60_L	0.716	1.00
245_F	249_L	0.716	1.00
491_T	499_E	0.716	1.00
385_E	390_S	0.711	1.00
91_S	94_D	0.711	1.00
449_L	464_L	0.710	1.00
40_V	273_L	0.710	1.00
115_L	119_G	0.709	1.00
14_I	83_R	0.708	1.00
14_I	76_I	0.708	1.00
261_R	265_G	0.707	1.00
430_A	437_A	0.706	1.00
151_Q	274_T	0.705	1.00
353_K	514_L	0.705	1.00
137_M	288_E	0.705	1.00
91_S	310_L	0.702	1.00
149_F	160_V	0.702	1.00
144_V	282_Y	0.701	1.00
92_F	310_L	0.700	1.00
64_I	68_G	0.699	1.00
350_F	354_K	0.698	1.00
11_M	14_I	0.696	1.00
502_I	505_T	0.696	1.00
551_K	554_V	0.695	1.00
471_R	498_T	0.694	1.00
417_L	446_V	0.693	1.00
399_W	403_L	0.692	1.00
412_I	457_I	0.692	1.00
499_E	524_W	0.692	1.00
155_S	261_R	0.691	1.00
386_V	391_R	0.691	1.00
168_I	171_I	0.687	1.00
175_L	179_R	0.687	1.00
434_T	446_V	0.687	1.00
530_E	544_T	0.685	1.00
356_I	542_I	0.685	1.00
134_M	138_A	0.685	1.00
525_M	528_M	0.684	1.00
152_D	267_I	0.683	1.00
324_E	395_Q	0.683	1.00
414_D	458_G	0.681	1.00
474_L	478_F	0.681	1.00
554_V	558_L	0.680	1.00
34_E	151_Q	0.680	1.00
425_H	481_N	0.680	1.00
42_G	45_N	0.679	1.00
370_I	516_F	0.678	1.00
341_R	368_T	0.677	1.00
42_G	51_S	0.676	1.00
372_I	377_L	0.676	1.00
144_V	281_E	0.675	1.00
146_I	149_F	0.675	1.00
183_R	186_K	0.674	1.00
425_H	480_G	0.673	1.00
99_L	314_G	0.672	1.00
541_E	554_V	0.671	1.00
119_G	185_W	0.671	1.00
371_D	377_L	0.671	1.00
358_I	516_F	0.671	1.00
13_R	16_T	0.670	1.00
17_L	76_I	0.669	1.00
88_L	120_I	0.669	1.00
95_Q	312_Q	0.668	1.00
322_Q	395_Q	0.667	1.00
441_G	444_E	0.666	1.00
304_K	308_E	0.666	1.00
123_F	303_G	0.665	1.00
432_D	436_A	0.665	1.00
108_G	193_N	0.663	1.00
486_L	516_F	0.662	1.00
334_L	346_I	0.662	1.00
152_D	155_S	0.659	1.00
329_Q	514_L	0.659	1.00
233_L	237_F	0.659	1.00
313_P	317_E	0.658	1.00
30_I	33_A	0.656	1.00
94_D	215_S	0.653	1.00
114_T	192_S	0.653	1.00
299_G	302_A	0.652	1.00
85_G	89_R	0.652	1.00
185_W	188_Y	0.652	1.00
541_E	548_L	0.650	1.00
415_D	456_R	0.647	1.00
348_L	539_V	0.646	1.00
189_Q	305_T	0.646	1.00
88_L	123_F	0.644	1.00
474_L	502_I	0.644	1.00
340_G	381_G	0.642	1.00
439_S	505_T	0.642	1.00
555_Y	558_L	0.639	1.00
541_E	549_L	0.639	1.00
545_H	548_L	0.637	1.00
244_D	287_R	0.637	1.00
387_N	483_P	0.636	1.00
414_D	463_A	0.635	1.00
249_L	253_T	0.635	1.00
499_E	523_H	0.634	1.00
422_R	437_A	0.634	1.00
85_G	124_R	0.634	1.00
53_L	56_I	0.633	1.00
41_T	45_N	0.633	1.00
333_K	383_M	0.632	1.00
92_F	120_I	0.632	1.00
257_F	260_L	0.631	1.00
22_T	73_R	0.631	1.00
328_D	402_N	0.630	1.00
83_R	86_A	0.630	1.00
425_H	429_S	0.630	1.00
346_I	534_L	0.630	1.00
180_K	183_R	0.628	1.00
101_P	105_K	0.627	1.00
123_F	306_I	0.625	1.00
542_I	547_E	0.624	1.00
25_Q	70_T	0.624	1.00
409_H	460_G	0.624	1.00
355_K	527_D	0.624	1.00
551_K	556_T	0.623	1.00
24_I	28_A	0.620	1.00
433_T	436_A	0.619	1.00
337_V	382_G	0.619	1.00
31_M	62_A	0.618	1.00
440_A	474_L	0.618	1.00
78_Y	129_L	0.618	1.00
136_S	140_V	0.616	1.00
441_G	502_I	0.616	1.00
484_I	514_L	0.616	1.00
173_L	239_S	0.615	1.00
536_G	540_A	0.615	1.00
471_R	494_L	0.615	1.00
438_A	453_L	0.614	1.00
259_G	262_L	0.613	1.00
103_F	112_M	0.612	1.00
530_E	547_E	0.612	1.00
370_I	405_Y	0.611	1.00
351_K	356_I	0.610	1.00
16_T	19_T	0.609	1.00
337_V	347_H	0.608	1.00
159_L	279_A	0.608	1.00
111_Q	305_T	0.607	1.00
321_L	325_A	0.607	1.00
553_G	557_K	0.606	1.00
416_T	454_E	0.606	1.00
396_D	399_W	0.605	1.00
125_R	295_A	0.604	1.00
452_G	455_G	0.604	1.00
496_I	499_E	0.604	1.00
350_F	355_K	0.604	1.00
420_N	472_V	0.603	1.00
169_F	246_F	0.602	1.00
114_T	118_E	0.601	1.00
465_S	468_Q	0.599	1.00
433_T	437_A	0.599	1.00
267_I	271_P	0.599	1.00
531_I	544_T	0.598	1.00
284_L	288_E	0.596	1.00
362_S	519_T	0.596	1.00
438_A	444_E	0.596	1.00
86_A	222_S	0.595	1.00
100_G	103_F	0.594	1.00
258_L	262_L	0.594	1.00
330_D	483_P	0.594	1.00
81_A	128_E	0.593	1.00
185_W	301_E	0.593	1.00
49_I	53_L	0.592	1.00
11_M	84_T	0.591	1.00
164_P	168_I	0.591	1.00
187_S	225_Y	0.591	1.00
51_S	55_V	0.589	1.00
302_A	305_T	0.589	1.00
541_E	557_K	0.588	1.00
440_A	478_F	0.587	1.00
181_A	232_T	0.587	1.00
425_H	479_L	0.587	1.00
231_S	235_V	0.586	1.00
406_I	487_L	0.586	1.00
337_V	384_I	0.586	1.00
404_L	480_G	0.585	1.00
443_T	446_V	0.584	1.00
204_T	207_F	0.584	1.00
93_L	97_F	0.584	1.00
69_M	72_A	0.584	1.00
379_P	390_S	0.581	1.00
417_L	457_I	0.581	1.00
526_L	545_H	0.581	1.00
503_K	517_L	0.581	1.00
114_T	188_Y	0.580	1.00
436_A	475_A	0.580	1.00
494_L	498_T	0.579	1.00
533_V	541_E	0.579	1.00
121_S	124_R	0.579	1.00
319_T	323_L	0.577	1.00
346_I	532_I	0.576	1.00
344_S	347_H	0.576	1.00
82_A	85_G	0.575	1.00
25_Q	69_M	0.575	1.00
137_M	141_P	0.574	1.00
484_I	516_F	0.573	1.00
50_T	53_L	0.573	1.00
328_D	352_G	0.573	1.00
505_T	508_D	0.572	1.00
167_I	170_M	0.571	1.00
37_S	270_G	0.571	1.00
172_L	175_L	0.570	1.00
316_K	375_G	0.569	1.00
495_D	498_T	0.569	1.00
422_R	479_L	0.568	1.00
253_T	257_F	0.568	1.00
371_D	405_Y	0.567	1.00
362_S	494_L	0.567	1.00
60_L	64_I	0.566	1.00
227_K	230_M	0.566	1.00
194_H	198_S	0.566	1.00
461_G	469_A	0.565	1.00
120_I	306_I	0.565	1.00
125_R	129_L	0.565	1.00
114_T	189_Q	0.564	1.00
144_V	278_L	0.564	1.00
102_R	342_S	0.563	1.00
320_P	323_L	0.562	1.00
183_R	224_R	0.562	1.00
186_K	190_R	0.560	1.00
180_K	232_T	0.560	1.00
435_R	509_L	0.560	1.00
153_R	156_A	0.559	1.00
498_T	502_I	0.558	1.00
467_G	495_D	0.558	1.00
386_V	394_L	0.558	1.00
389_T	398_S	0.557	1.00
321_L	395_Q	0.556	1.00
201_G	413_F	0.555	1.00
478_F	509_L	0.555	1.00
154_T	257_F	0.555	1.00
406_I	490_P	0.554	1.00
109_T	113_V	0.550	1.00
78_Y	82_A	0.548	1.00
67_H	71_V	0.548	1.00
549_L	552_N	0.548	1.00
101_P	376_F	0.547	1.00
118_E	185_W	0.546	1.00
97_F	100_G	0.546	1.00
14_I	80_Y	0.546	1.00
533_V	540_A	0.546	1.00
332_L	350_F	0.546	1.00
319_T	395_Q	0.546	1.00
421_I	424_Y	0.545	1.00
104_A	107_E	0.545	1.00
350_F	532_I	0.544	1.00
194_H	214_H	0.544	1.00
321_L	393_H	0.544	1.00
106_K	342_S	0.543	1.00
504_E	527_D	0.543	1.00
115_L	305_T	0.543	1.00
540_A	552_N	0.542	1.00
328_D	386_V	0.541	1.00
133_K	288_E	0.540	1.00
145_V	149_F	0.540	1.00
338_S	343_V	0.540	1.00
165_I	169_F	0.537	1.00
510_F	513_K	0.537	1.00
359_I	525_M	0.537	1.00
34_E	274_T	0.537	1.00
248_M	252_A	0.536	1.00
431_E	438_A	0.536	1.00
407_P	410_P	0.535	1.00
58_F	62_A	0.534	1.00
490_P	519_T	0.534	1.00
368_T	372_I	0.534	1.00
184_Q	232_T	0.533	1.00
110_G	193_N	0.533	1.00
338_S	347_H	0.533	1.00
141_P	145_V	0.533	1.00
237_F	241_F	0.531	1.00
321_L	398_S	0.530	1.00
351_K	514_L	0.530	1.00
355_K	512_D	0.530	1.00
533_V	553_G	0.529	1.00
358_I	534_L	0.527	1.00
72_A	76_I	0.527	1.00
505_T	509_L	0.527	1.00
160_V	164_P	0.527	1.00
191_L	195_F	0.526	1.00
368_T	377_L	0.525	1.00
165_I	168_I	0.525	1.00
29_I	66_R	0.524	1.00
517_L	525_M	0.523	1.00
359_I	522_L	0.523	1.00
34_E	278_L	0.522	1.00
446_V	449_L	0.522	1.00
535_D	557_K	0.522	1.00
417_L	442_L	0.522	1.00
367_S	370_I	0.521	1.00
428_A	433_T	0.521	1.00
150_F	154_T	0.520	1.00
137_M	289_V	0.520	1.00
478_F	505_T	0.520	1.00
349_S	352_G	0.519	1.00
159_L	282_Y	0.518	1.00
225_Y	229_T	0.518	1.00
496_I	523_H	0.517	1.00
503_K	527_D	0.517	1.00
320_P	324_E	0.516	1.00
516_F	532_I	0.516	1.00
420_N	476_R	0.514	1.00
43_L	51_S	0.513	1.00
26_T	30_I	0.512	1.00
327_S	330_D	0.512	1.00
440_A	445_L	0.511	1.00
504_E	507_L	0.511	1.00
140_V	144_V	0.511	1.00
471_R	493_H	0.511	1.00
334_L	372_I	0.510	1.00
278_L	285_P	0.509	1.00
509_L	512_D	0.509	1.00
129_L	133_K	0.509	1.00
490_P	517_L	0.508	1.00
519_T	523_H	0.508	1.00
375_G	391_R	0.508	1.00
328_D	331_E	0.507	1.00
205_L	211_S	0.506	1.00
189_Q	301_E	0.506	1.00
35_W	38_E	0.505	1.00
35_W	59_F	0.505	1.00
137_M	140_V	0.505	1.00
75_K	79_Q	0.505	1.00
358_I	518_A	0.503	1.00
85_G	120_I	0.503	1.00
373_L	486_L	0.503	1.00
188_Y	192_S	0.502	1.00
267_I	272_A	0.502	1.00
446_V	452_G	0.501	1.00
139_I	143_A	0.501	1.00
116_A	120_I	0.501	1.00
318_E	323_L	0.501	1.00
498_T	501_E	0.500	1.00
416_T	456_R	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4ry2A	2	0.9735	100	0.084	Contact Map
4a82A	2	0.9947	100	0.11	Contact Map
4f4cA	1	0.9735	100	0.151	Contact Map
4q4hB	1	0.9929	100	0.152	Contact Map
3b60A	2	0.9912	100	0.157	Contact Map
3b5xA	2	0.9912	100	0.158	Contact Map
4q4hA	1	0.9929	100	0.166	Contact Map
3zdqA	2	0.9718	100	0.167	Contact Map
4mrsA	2	1	100	0.167	Contact Map
4q9hA	1	0.9929	100	0.171	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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