CYDA - BACSU - GREMLIN Contacts

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CYDA - Cytochrome bd ubiquinol oxidase subunit 1

UniProt:	P94364	Sequences: MSELVLARIQFASTTLFHFLFVPMSIGLVFMVALMETLYLVKKNELYLKMAKFWGHLFLINFAVGVVTGILQEFQFGLNWSDYSRFVGDVFGAPLAIEALLAFFMESIFIGLWIFGWDRLPKKIHALCIWLVSFGTIMSSFWILTANSFMQEPVGFTIKNGRAEMNDFGALITNPQLWVEFPHVIFGALATGAFFIAGVSAFKLLKKKEVPFFKQSFKLAMIVGLCAGLGVGLSGHMQAEHLMESQPMKMAASEGLWEDSGDPAAWTAFATIDTKNEKSSNEIKVPYALSYLAYQKFSGSVKGMKTLQAEYEKIYGKGDYIPPVKTTFWSFRIMVGAGVVMILAALGGLWLNRRKKLENSKWYLRIMIALISFPFLANSAGWIMTEIGRQPWTVMGLMTTAQSVSPNVTAGSLLFSIIAFGVMYMILGALLVFLFIREIKKGAEHDNHHDVPVSTDPFSQEVYHGISS	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	468 (436)
Sequences:	2868 (1510)
Seq/√Len:	72.3

ECOLI - CYDA APPC
BACSU - CYDA YTHA
HALSA - O54610

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
167_D	170_A	6.346	1.00
273_D	280_S	5.242	1.00
393_T	403_S	5.074	1.00
232_G	342_I	4.507	1.00
198_G	371_I	4.392	1.00
294_Y	299_G	4.245	1.00
273_D	276_N	3.986	1.00
258_E	305_K	3.980	1.00
310_E	320_Y	3.975	1.00
291_Y	297_F	3.901	1.00
127_L	131_L	3.777	1.00
270_A	279_S	3.708	1.00
263_P	287_Y	3.441	1.00
236_H	240_E	3.006	1.00
186_F	234_S	2.914	1.00
339_V	343_L	2.906	1.00
240_E	295_Q	2.855	1.00
236_H	295_Q	2.774	1.00
221_M	348_G	2.739	1.00
43_K	122_K	2.671	1.00
320_Y	399_T	2.637	1.00
411_G	415_F	2.571	1.00
262_D	300_S	2.570	1.00
194_F	224_G	2.553	1.00
277_E	305_K	2.529	1.00
361_K	365_R	2.524	1.00
277_E	321_I	2.522	1.00
414_L	418_I	2.498	1.00
351_L	363_Y	2.447	1.00
33_A	130_W	2.356	1.00
337_A	341_M	2.318	1.00
383_I	387_I	2.258	1.00
287_Y	297_F	2.247	1.00
267_T	328_F	2.228	1.00
267_T	284_K	2.209	1.00
248_M	307_L	2.155	1.00
4_L	404_V	2.142	1.00
259_D	306_T	2.115	1.00
40_L	126_A	2.097	1.00
362_W	365_R	2.097	1.00
34_L	38_L	2.010	1.00
37_T	126_A	2.001	1.00
120_L	128_C	2.000	1.00
265_A	284_K	1.981	1.00
326_T	387_I	1.958	1.00
337_A	373_F	1.942	1.00
16_L	379_S	1.936	1.00
257_W	279_S	1.931	1.00
191_T	378_N	1.925	1.00
19_F	184_V	1.910	1.00
218_K	352_N	1.910	1.00
228_G	342_I	1.895	1.00
260_S	264_A	1.866	1.00
157_T	160_N	1.862	1.00
333_I	380_A	1.858	1.00
7_A	413_L	1.843	1.00
279_S	282_E	1.831	1.00
37_T	130_W	1.816	1.00
399_T	402_Q	1.805	1.00
309_A	321_I	1.783	1.00
186_F	230_G	1.772	1.00
343_L	347_G	1.758	1.00
348_G	363_Y	1.757	1.00
436_I	440_K	1.755	1.00
274_T	325_K	1.748	1.00
390_Q	400_T	1.721	1.00
347_G	351_L	1.696	1.00
45_E	49_K	1.682	1.00
13_S	421_G	1.680	1.00
232_G	339_V	1.673	1.00
17_F	428_G	1.665	1.00
112_L	120_L	1.664	1.00
82_D	85_R	1.661	1.00
340_V	370_L	1.635	0.99
9_I	417_I	1.623	0.99
3_E	7_A	1.617	0.99
344_A	370_L	1.615	0.99
157_T	164_E	1.607	0.99
190_A	228_G	1.605	0.99
16_L	383_I	1.601	0.99
87_V	91_F	1.585	0.99
121_P	124_I	1.577	0.99
46_L	215_Q	1.564	0.99
2_S	5_V	1.562	0.99
323_P	387_I	1.555	0.99
200_S	216_S	1.543	0.99
117_W	125_H	1.536	0.99
50_M	216_S	1.535	0.99
205_L	361_K	1.532	0.99
344_A	366_I	1.528	0.99
302_K	306_T	1.525	0.99
296_K	299_G	1.514	0.99
351_L	360_S	1.507	0.99
32_V	51_A	1.467	0.99
291_Y	295_Q	1.445	0.99
32_V	129_I	1.432	0.99
57_L	195_F	1.431	0.99
165_M	171_L	1.419	0.99
259_D	300_S	1.415	0.99
57_L	435_F	1.408	0.98
422_V	426_I	1.405	0.98
35_M	50_M	1.404	0.98
197_A	221_M	1.399	0.98
336_G	340_V	1.396	0.98
169_G	172_I	1.395	0.98
156_F	397_L	1.385	0.98
152_E	176_Q	1.383	0.98
52_K	117_W	1.367	0.98
270_A	282_E	1.362	0.98
86_F	163_A	1.355	0.98
253_S	384_M	1.341	0.98
5_V	9_I	1.340	0.98
105_M	135_G	1.339	0.98
36_E	126_A	1.338	0.98
365_R	369_A	1.333	0.98
425_M	429_A	1.323	0.98
271_T	329_W	1.317	0.98
39_Y	48_L	1.308	0.98
228_G	345_A	1.303	0.97
25_S	61_N	1.303	0.97
203_K	208_K	1.281	0.97
24_M	195_F	1.279	0.97
54_W	216_S	1.275	0.97
38_L	41_V	1.273	0.97
59_L	114_I	1.267	0.97
140_S	185_I	1.262	0.97
370_L	373_F	1.260	0.97
197_A	217_F	1.253	0.97
276_N	280_S	1.250	0.97
12_A	387_I	1.250	0.97
205_L	368_I	1.249	0.97
287_Y	291_Y	1.244	0.97
145_T	177_L	1.239	0.97
48_L	52_K	1.237	0.97
308_Q	320_Y	1.232	0.96
218_K	222_I	1.232	0.96
193_A	220_A	1.227	0.96
418_I	422_V	1.217	0.96
91_F	146_A	1.216	0.96
398_M	403_S	1.211	0.96
194_F	344_A	1.207	0.96
302_K	310_E	1.204	0.96
287_Y	298_S	1.200	0.96
13_S	417_I	1.198	0.96
256_L	267_T	1.197	0.96
3_E	410_A	1.195	0.96
181_F	185_I	1.194	0.96
33_A	37_T	1.185	0.96
97_I	168_F	1.167	0.95
112_L	128_C	1.165	0.95
260_S	265_A	1.164	0.95
202_F	206_K	1.164	0.95
26_I	188_A	1.161	0.95
144_L	177_L	1.161	0.95
30_F	133_S	1.160	0.95
31_M	219_L	1.158	0.95
130_W	134_F	1.155	0.95
24_M	28_L	1.153	0.95
194_F	341_M	1.140	0.94
433_F	437_R	1.138	0.94
197_A	220_A	1.138	0.94
263_P	298_S	1.124	0.94
250_M	301_V	1.123	0.94
350_W	353_R	1.121	0.94
323_P	326_T	1.121	0.94
228_G	232_G	1.119	0.94
137_I	185_I	1.119	0.94
31_M	223_V	1.115	0.94
243_M	293_A	1.113	0.94
182_P	234_S	1.113	0.94
34_L	219_L	1.112	0.94
38_L	44_N	1.110	0.94
193_A	224_G	1.100	0.93
336_G	339_V	1.098	0.93
199_V	439_I	1.090	0.93
349_L	353_R	1.081	0.93
7_A	408_V	1.078	0.93
419_A	423_M	1.070	0.92
24_M	375_F	1.066	0.92
274_T	323_P	1.064	0.92
187_G	378_N	1.060	0.92
250_M	253_S	1.060	0.92
347_G	362_W	1.057	0.92
333_I	376_L	1.057	0.92
415_F	419_A	1.057	0.92
376_L	380_A	1.050	0.92
214_K	218_K	1.045	0.91
243_M	250_M	1.044	0.91
205_L	365_R	1.032	0.91
30_F	34_L	1.030	0.91
141_F	145_T	1.028	0.91
152_E	241_H	1.028	0.91
192_G	374_P	1.028	0.91
217_F	367_M	1.024	0.91
4_L	401_A	1.016	0.90
113_W	129_I	1.014	0.90
50_M	212_F	1.011	0.90
176_Q	245_S	1.009	0.90
184_V	187_G	1.006	0.90
36_E	129_I	1.001	0.90
416_S	419_A	1.000	0.90
157_T	166_N	1.000	0.90
132_V	136_T	0.998	0.89
225_L	349_L	0.996	0.89
194_F	367_M	0.994	0.89
179_V	241_H	0.991	0.89
248_M	304_M	0.990	0.89
36_E	117_W	0.988	0.89
308_Q	321_I	0.986	0.89
224_G	345_A	0.984	0.89
87_V	394_V	0.981	0.89
267_T	270_A	0.981	0.89
363_Y	367_M	0.978	0.88
39_Y	117_W	0.977	0.88
293_A	301_V	0.972	0.88
271_T	281_N	0.971	0.88
205_L	364_L	0.969	0.88
126_A	130_W	0.968	0.88
35_M	219_L	0.966	0.88
45_E	48_L	0.964	0.88
344_A	373_F	0.958	0.87
51_A	117_W	0.954	0.87
124_I	127_L	0.952	0.87
340_V	343_L	0.951	0.87
356_K	359_N	0.948	0.87
343_L	346_L	0.945	0.87
201_A	364_L	0.944	0.87
133_S	137_I	0.943	0.87
202_F	368_I	0.937	0.86
197_A	367_M	0.937	0.86
179_V	237_M	0.936	0.86
178_W	182_P	0.935	0.86
48_L	117_W	0.924	0.85
123_K	127_L	0.922	0.85
256_L	301_V	0.915	0.85
241_H	245_S	0.914	0.85
37_T	41_V	0.913	0.85
323_P	327_T	0.912	0.85
344_A	367_M	0.910	0.85
294_Y	298_S	0.910	0.85
351_L	356_K	0.909	0.85
266_W	292_L	0.909	0.85
131_L	135_G	0.905	0.84
30_F	33_A	0.904	0.84
6_L	414_L	0.904	0.84
257_W	305_K	0.899	0.84
9_I	13_S	0.895	0.84
210_V	214_K	0.894	0.84
259_D	302_K	0.892	0.83
393_T	398_M	0.886	0.83
289_L	301_V	0.885	0.83
260_S	263_P	0.882	0.83
160_N	164_E	0.881	0.83
226_C	230_G	0.880	0.83
233_L	237_M	0.879	0.83
176_Q	180_E	0.878	0.82
260_S	300_S	0.877	0.82
340_V	344_A	0.877	0.82
83_Y	87_V	0.876	0.82
259_D	303_G	0.876	0.82
190_A	231_V	0.872	0.82
12_A	326_T	0.869	0.82
346_L	350_W	0.869	0.82
182_P	186_F	0.865	0.81
152_E	175_P	0.864	0.81
15_T	72_Q	0.863	0.81
256_L	302_K	0.862	0.81
6_L	417_I	0.861	0.81
285_V	288_A	0.860	0.81
225_L	346_L	0.859	0.81
222_I	352_N	0.857	0.81
118_D	122_K	0.853	0.81
305_K	321_I	0.846	0.80
134_F	138_M	0.843	0.80
271_T	280_S	0.839	0.79
266_W	335_V	0.839	0.79
222_I	349_L	0.839	0.79
51_A	55_G	0.839	0.79
348_G	367_M	0.838	0.79
212_F	443_A	0.836	0.79
327_T	384_M	0.834	0.79
250_M	289_L	0.832	0.79
145_T	385_T	0.831	0.79
256_L	260_S	0.830	0.79
159_K	162_R	0.829	0.79
185_I	189_L	0.825	0.78
267_T	279_S	0.825	0.78
195_F	375_F	0.824	0.78
44_N	211_P	0.823	0.78
411_G	414_L	0.820	0.78
410_A	413_L	0.820	0.78
267_T	282_E	0.818	0.78
141_F	172_I	0.818	0.78
53_F	442_G	0.807	0.77
287_Y	299_G	0.807	0.77
227_A	231_V	0.804	0.77
436_I	439_I	0.803	0.76
189_L	227_A	0.803	0.76
415_F	418_I	0.802	0.76
264_A	299_G	0.797	0.76
122_K	126_A	0.796	0.76
40_L	123_K	0.796	0.76
201_A	217_F	0.795	0.76
408_V	413_L	0.794	0.76
230_G	234_S	0.792	0.75
437_R	441_K	0.791	0.75
242_L	253_S	0.790	0.75
49_K	444_E	0.789	0.75
290_S	301_V	0.788	0.75
393_T	400_T	0.786	0.75
156_F	166_N	0.786	0.75
190_A	224_G	0.785	0.75
257_W	274_T	0.785	0.75
83_Y	89_D	0.784	0.75
432_V	436_I	0.784	0.75
89_D	162_R	0.784	0.75
47_Y	443_A	0.783	0.75
340_V	366_I	0.783	0.75
410_A	414_L	0.783	0.75
203_K	442_G	0.782	0.75
426_I	430_L	0.776	0.74
418_I	421_G	0.776	0.74
179_V	238_Q	0.775	0.74
119_R	440_K	0.771	0.73
260_S	284_K	0.768	0.73
228_G	338_G	0.767	0.73
275_K	278_K	0.767	0.73
327_T	330_S	0.766	0.73
60_I	438_E	0.764	0.73
75_Q	80_W	0.763	0.73
17_F	21_F	0.755	0.72
327_T	383_I	0.753	0.72
341_M	370_L	0.753	0.72
330_S	384_M	0.751	0.71
242_L	385_T	0.750	0.71
273_D	279_S	0.750	0.71
148_S	174_N	0.749	0.71
271_T	325_K	0.748	0.71
270_A	284_K	0.747	0.71
23_P	91_F	0.747	0.71
40_L	122_K	0.744	0.71
45_E	122_K	0.744	0.71
290_S	299_G	0.743	0.71
300_S	306_T	0.743	0.71
270_A	281_N	0.740	0.70
223_V	227_A	0.740	0.70
225_L	345_A	0.739	0.70
190_A	341_M	0.738	0.70
347_G	366_I	0.738	0.70
117_W	129_I	0.738	0.70
76_F	95_L	0.736	0.70
61_N	195_F	0.735	0.70
420_F	427_L	0.735	0.70
19_F	378_N	0.732	0.70
67_V	396_G	0.732	0.70
55_G	113_W	0.732	0.70
196_I	220_A	0.732	0.70
259_D	301_V	0.731	0.69
347_G	350_W	0.730	0.69
87_V	149_F	0.730	0.69
269_F	281_N	0.729	0.69
264_A	303_G	0.729	0.69
408_V	412_S	0.729	0.69
71_L	424_Y	0.727	0.69
26_I	137_I	0.725	0.69
37_T	40_L	0.722	0.68
102_A	139_S	0.722	0.68
188_A	231_V	0.722	0.68
330_S	380_A	0.720	0.68
222_I	226_C	0.718	0.68
124_I	128_C	0.718	0.68
404_V	413_L	0.716	0.68
148_S	180_E	0.716	0.68
243_M	302_K	0.713	0.68
157_T	165_M	0.712	0.67
93_A	165_M	0.709	0.67
250_M	293_A	0.707	0.67
302_K	307_L	0.706	0.67
188_A	378_N	0.705	0.67
60_I	434_L	0.705	0.67
120_L	124_I	0.701	0.66
31_M	196_I	0.701	0.66
97_I	142_W	0.699	0.66
47_Y	50_M	0.699	0.66
136_T	189_L	0.698	0.66
30_F	137_I	0.698	0.66
90_V	165_M	0.698	0.66
412_S	415_F	0.698	0.66
109_F	128_C	0.695	0.66
372_S	376_L	0.694	0.65
307_L	321_I	0.694	0.65
342_I	346_L	0.693	0.65
349_L	352_N	0.693	0.65
425_M	428_G	0.692	0.65
289_L	292_L	0.690	0.65
327_T	387_I	0.690	0.65
49_K	209_E	0.690	0.65
339_V	347_G	0.688	0.65
207_K	361_K	0.687	0.65
193_A	227_A	0.680	0.64
206_K	369_A	0.680	0.64
262_D	302_K	0.679	0.64
176_Q	241_H	0.677	0.64
158_I	163_A	0.676	0.63
335_V	377_A	0.676	0.63
258_E	300_S	0.676	0.63
6_L	413_L	0.676	0.63
83_Y	90_V	0.675	0.63
109_F	135_G	0.673	0.63
263_P	299_G	0.673	0.63
97_I	101_L	0.673	0.63
273_D	278_K	0.673	0.63
90_V	163_A	0.671	0.63
30_F	130_W	0.671	0.63
36_E	40_L	0.670	0.63
102_A	138_M	0.669	0.63
279_S	324_V	0.668	0.62
77_G	92_G	0.668	0.62
44_N	49_K	0.667	0.62
239_A	332_R	0.666	0.62
326_T	383_I	0.666	0.62
41_V	44_N	0.666	0.62
257_W	321_I	0.665	0.62
105_M	131_L	0.665	0.62
248_M	395_M	0.664	0.62
204_L	210_V	0.663	0.62
263_P	296_K	0.663	0.62
416_S	439_I	0.655	0.61
112_L	434_L	0.654	0.61
38_L	47_Y	0.653	0.61
7_A	404_V	0.652	0.61
255_G	304_M	0.648	0.60
148_S	177_L	0.646	0.60
57_L	438_E	0.646	0.60
81_S	84_S	0.643	0.60
363_Y	366_I	0.642	0.59
337_A	377_A	0.642	0.59
283_I	288_A	0.641	0.59
30_F	189_L	0.641	0.59
257_W	282_E	0.640	0.59
46_L	50_M	0.640	0.59
29_V	32_V	0.639	0.59
72_Q	75_Q	0.637	0.59
269_F	282_E	0.636	0.59
155_G	171_L	0.636	0.59
159_K	164_E	0.635	0.59
203_K	213_F	0.634	0.58
398_M	402_Q	0.633	0.58
306_T	309_A	0.633	0.58
102_A	143_I	0.631	0.58
203_K	443_A	0.631	0.58
49_K	446_D	0.630	0.58
43_K	355_K	0.629	0.58
188_A	326_T	0.629	0.58
34_L	42_K	0.627	0.58
36_E	48_L	0.625	0.57
291_Y	296_K	0.625	0.57
195_F	435_F	0.622	0.57
21_F	67_V	0.621	0.57
268_A	285_V	0.621	0.57
203_K	439_I	0.620	0.57
42_K	51_A	0.619	0.57
274_T	324_V	0.619	0.57
344_A	363_Y	0.618	0.57
38_L	42_K	0.618	0.57
409_T	412_S	0.617	0.56
73_E	146_A	0.613	0.56
258_E	310_E	0.612	0.56
335_V	339_V	0.612	0.56
49_K	212_F	0.611	0.56
137_I	189_L	0.611	0.56
405_S	408_V	0.610	0.56
142_W	172_I	0.609	0.55
72_Q	78_L	0.609	0.55
255_G	332_R	0.609	0.55
350_W	354_R	0.608	0.55
287_Y	296_K	0.608	0.55
413_L	417_I	0.607	0.55
263_P	297_F	0.606	0.55
194_F	337_A	0.605	0.55
347_G	360_S	0.604	0.55
46_L	211_P	0.604	0.55
187_G	231_V	0.603	0.55
265_A	282_E	0.603	0.55
82_D	398_M	0.601	0.54
256_L	289_L	0.601	0.54
221_M	351_L	0.600	0.54
337_A	380_A	0.600	0.54
117_W	442_G	0.599	0.54
191_T	383_I	0.598	0.54
214_K	358_E	0.598	0.54
274_T	277_E	0.597	0.54
42_K	47_Y	0.597	0.54
55_G	117_W	0.597	0.54
52_K	359_N	0.596	0.54
144_L	184_V	0.596	0.54
94_P	171_L	0.595	0.54
190_A	227_A	0.594	0.54
209_E	442_G	0.593	0.53
22_V	91_F	0.592	0.53
84_S	87_V	0.590	0.53
228_G	337_A	0.589	0.53
221_M	349_L	0.589	0.53
61_N	73_E	0.588	0.53
431_L	435_F	0.587	0.53
25_S	64_V	0.587	0.53
325_K	329_W	0.587	0.53
366_I	370_L	0.587	0.53
276_N	279_S	0.586	0.53
196_I	223_V	0.584	0.52
113_W	125_H	0.583	0.52
7_A	58_F	0.582	0.52
258_E	309_A	0.582	0.52
203_K	206_K	0.582	0.52
368_I	371_I	0.581	0.52
121_P	127_L	0.581	0.52
74_F	99_A	0.580	0.52
32_V	58_F	0.579	0.52
427_L	431_L	0.578	0.52
226_C	348_G	0.577	0.52
273_D	277_E	0.577	0.52
155_G	170_A	0.577	0.52
421_G	425_M	0.576	0.51
239_A	292_L	0.576	0.51
35_M	51_A	0.575	0.51
234_S	237_M	0.573	0.51
29_V	145_T	0.572	0.51
288_A	339_V	0.572	0.51
244_E	275_K	0.572	0.51
270_A	328_F	0.572	0.51
38_L	219_L	0.571	0.51
134_F	169_G	0.571	0.51
197_A	370_L	0.570	0.51
111_G	114_I	0.570	0.51
30_F	223_V	0.569	0.51
419_A	424_Y	0.569	0.51
3_E	404_V	0.568	0.50
328_F	332_R	0.568	0.50
44_N	47_Y	0.568	0.50
229_L	342_I	0.568	0.50
255_G	270_A	0.567	0.50
397_L	401_A	0.566	0.50
276_N	281_N	0.565	0.50
365_R	368_I	0.565	0.50
404_V	435_F	0.565	0.50
50_M	54_W	0.564	0.50
175_P	241_H	0.564	0.50
251_A	306_T	0.564	0.50
127_L	134_F	0.563	0.50
341_M	373_F	0.562	0.50
14_T	72_Q	0.562	0.50
422_V	425_M	0.562	0.50
123_K	126_A	0.562	0.50
170_A	173_T	0.561	0.50
360_S	364_L	0.561	0.50
258_E	276_N	0.560	0.49
264_A	297_F	0.559	0.49
149_F	171_L	0.558	0.49
52_K	122_K	0.558	0.49
238_Q	241_H	0.557	0.49
438_E	441_K	0.557	0.49
213_F	216_S	0.556	0.49
93_A	168_F	0.556	0.49
263_P	300_S	0.556	0.49
242_L	327_T	0.556	0.49
83_Y	91_F	0.555	0.49
99_A	289_L	0.554	0.49
33_A	129_I	0.554	0.49
7_A	405_S	0.552	0.48
17_F	68_T	0.551	0.48
107_S	378_N	0.550	0.48
19_F	374_P	0.550	0.48
217_F	364_L	0.550	0.48
76_F	84_S	0.549	0.48
126_A	129_I	0.548	0.48
89_D	163_A	0.548	0.48
352_N	355_K	0.547	0.48
141_F	177_L	0.546	0.48
137_I	141_F	0.546	0.48
61_N	375_F	0.545	0.48
17_F	64_V	0.545	0.48
225_L	229_L	0.544	0.47
251_A	289_L	0.543	0.47
197_A	348_G	0.543	0.47
152_E	245_S	0.543	0.47
31_M	220_A	0.540	0.47
14_T	75_Q	0.540	0.47
211_P	215_Q	0.539	0.47
180_E	236_H	0.539	0.47
407_N	410_A	0.537	0.47
175_P	245_S	0.535	0.46
49_K	445_H	0.534	0.46
307_L	310_E	0.534	0.46
212_F	216_S	0.532	0.46
195_F	439_I	0.531	0.46
28_L	195_F	0.531	0.46
119_R	437_R	0.530	0.46
233_L	339_V	0.529	0.46
380_A	383_I	0.529	0.46
414_L	419_A	0.526	0.45
70_I	108_I	0.525	0.45
6_L	418_I	0.525	0.45
141_F	181_F	0.524	0.45
209_E	213_F	0.524	0.45
433_F	436_I	0.524	0.45
335_V	338_G	0.524	0.45
83_Y	150_M	0.524	0.45
243_M	299_G	0.524	0.45
439_I	442_G	0.522	0.45
3_E	414_L	0.522	0.45
49_K	56_H	0.521	0.45
361_K	364_L	0.520	0.45
158_I	310_E	0.520	0.45
209_E	443_A	0.520	0.45
14_T	420_F	0.518	0.44
74_F	77_G	0.518	0.44
180_E	385_T	0.517	0.44
207_K	210_V	0.517	0.44
10_Q	77_G	0.517	0.44
277_E	308_Q	0.515	0.44
279_S	284_K	0.515	0.44
56_H	441_K	0.515	0.44
209_E	445_H	0.514	0.44
386_E	389_R	0.513	0.44
59_L	110_I	0.512	0.44
2_S	9_I	0.512	0.44
226_C	237_M	0.512	0.44
226_C	359_N	0.511	0.43
5_V	323_P	0.511	0.43
26_I	30_F	0.511	0.43
122_K	361_K	0.510	0.43
24_M	35_M	0.510	0.43
17_F	425_M	0.510	0.43
228_G	341_M	0.510	0.43
39_Y	71_L	0.509	0.43
444_E	447_N	0.509	0.43
200_S	213_F	0.508	0.43
372_S	443_A	0.508	0.43
144_L	181_F	0.508	0.43
62_F	96_A	0.508	0.43
60_I	431_L	0.507	0.43
83_Y	86_F	0.506	0.43
123_K	226_C	0.505	0.43
107_S	438_E	0.505	0.43
272_I	329_W	0.504	0.43
180_E	238_Q	0.503	0.42
113_W	374_P	0.503	0.42
59_L	113_W	0.502	0.42
347_G	363_Y	0.502	0.42
25_S	435_F	0.502	0.42
393_T	399_T	0.501	0.42
277_E	309_A	0.501	0.42
240_E	293_A	0.500	0.42
286_P	331_F	0.500	0.42

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3mk7A	1	0.406	43.7	0.978	Contact Map
4xp4A	1	0.4231	28.8	0.98	Contact Map
2a65A	2	0.3889	22.5	0.981	Contact Map
4us3A	1	0.3077	21.6	0.981	Contact Map
3s8fA	1	0.4722	21.6	0.981	Contact Map
3w4tA	1	0.7735	18	0.982	Contact Map
2yevA	1	0.7521	17.7	0.982	Contact Map
3wfdB	1	0.3803	14.5	0.983	Contact Map
2ks1B	1	0.094	9.1	0.984	Contact Map
2f95B	2	0.1111	8.7	0.984	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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