ALDY - BACSU - GREMLIN Contacts

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ALDY - Uncharacterized aldehyde dehydrogenase AldY

UniProt:	P94358	Sequences: MSFETLNKSFINGKWTGGESGRTEDILNPYDQSVITTASLATGKQLEDAFDIAQKAQKEWAKSTTEDRKAVLQKARGYLHENRDDIIMMIARETGGTIIKSTIELEQTIAILDEAMTYTGELGGVKEVPSDIEGKTNKIYRLPLGVISSISPFNFPMNLSMRSIAPAIALGNSVVHKPDIQTAISGGTIIAKAFEHAGLPAGVLNVMLTDVKEIGDGMLTNPIPRLISFTGSTAVGRHIGEIAGRAFKRMALELGGNNPFAVLSDADVDRAVDAAIFGKFIHQGQICMIINRIIVHQDVYDEFVEKFTARVKQLPYGDQTDPKTVVGPLINERQIEKALEIIEQAKTDGIELAVEGKRVGNVLTPYVFVGADNNSKIAQTELFAPIATIIKAGSDQEAIDMANDTEYGLSSAVFTSDLEKGEKFALQIDSGMTHVNDQSVNDSPNIAFGGNKASGVGRFGNPWVVEEFTVTKWISIQKQYRKYPF	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	485 (452)
Sequences:	36347 (21751)
Seq/√Len:	1023.1

ECOLI - PUUC GABD ALDA BETB FEAB ABDH ALDB ASTD SAD EUTE PUTA PAAZ PROA ADHE
BACSU - ALDY ALDH5 ALDH1 ALDH4 ROCA ROCA2 IOLA BETB GABD ALDH3 ALDH2 PROA
HALSA - Q9HMJ6 Q9HQZ2 Q9HRB5 Q9HR91
SULSO - Q97YT9 KGSDH GAPN Q97XS9 Q97XA5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
297_Q	393_G	4.872	1.00
241_E	245_R	3.916	1.00
297_Q	391_K	3.109	1.00
269_D	306_K	3.072	1.00
300_Y	391_K	2.955	1.00
25_D	37_T	2.884	1.00
357_K	364_T	2.783	1.00
54_Q	223_I	2.775	1.00
264_S	296_H	2.691	1.00
344_Q	376_K	2.631	1.00
273_D	310_R	2.602	1.00
372_D	375_S	2.575	1.00
332_E	336_E	2.552	1.00
189_I	192_K	2.500	1.00
264_S	298_D	2.482	1.00
343_E	347_T	2.470	1.00
304_V	389_I	2.437	1.00
25_D	34_V	2.417	1.00
82_N	85_D	2.412	1.00
415_T	421_G	2.356	1.00
195_E	201_A	2.336	1.00
80_H	113_D	2.306	1.00
78_Y	196_H	2.197	1.00
42_T	45_Q	2.184	1.00
83_R	106_E	2.180	1.00
339_L	343_E	2.169	1.00
54_Q	225_R	2.138	1.00
406_E	453_A	2.107	1.00
342_I	363_L	2.103	1.00
84_D	102_T	2.100	1.00
220_T	242_I	2.076	1.00
395_D	420_K	2.068	1.00
216_D	220_T	2.060	1.00
181_Q	331_N	1.997	1.00
351_E	370_G	1.987	1.00
142_L	472_K	1.981	1.00
344_Q	348_D	1.967	1.00
339_L	358_R	1.965	1.00
75_A	194_F	1.946	1.00
141_R	466_E	1.944	1.00
423_K	427_Q	1.936	1.00
339_L	363_L	1.926	1.00
308_T	312_K	1.922	1.00
302_E	306_K	1.910	1.00
260_F	275_A	1.907	1.00
353_A	369_V	1.902	1.00
47_E	217_G	1.890	1.00
238_H	241_E	1.864	1.00
237_R	453_A	1.858	1.00
329_L	338_A	1.823	1.00
78_Y	81_E	1.820	1.00
71_V	199_L	1.816	1.00
346_K	352_L	1.812	1.00
51_D	223_I	1.806	1.00
265_D	420_K	1.779	1.00
85_D	189_I	1.768	1.00
378_A	390_I	1.763	1.00
294_I	401_M	1.754	1.00
34_V	37_T	1.750	1.00
82_N	196_H	1.737	1.00
47_E	51_D	1.717	1.00
429_D	452_K	1.690	1.00
141_R	469_T	1.669	1.00
308_T	353_A	1.646	1.00
73_Q	113_D	1.644	1.00
393_G	397_E	1.632	1.00
373_N	401_M	1.627	1.00
397_E	400_D	1.625	1.00
351_E	369_V	1.610	1.00
395_D	423_K	1.607	1.00
296_H	392_A	1.602	1.00
80_H	109_I	1.598	1.00
98_I	102_T	1.591	1.00
306_K	309_A	1.583	1.00
332_E	361_N	1.581	1.00
368_F	377_I	1.579	1.00
305_E	309_A	1.575	1.00
64_T	67_D	1.569	1.00
311_V	367_V	1.565	1.00
210_D	213_E	1.563	1.00
23_T	37_T	1.562	1.00
74_K	77_G	1.555	1.00
280_F	311_V	1.553	1.00
340_E	376_K	1.551	1.00
300_Y	304_V	1.550	1.00
112_L	165_A	1.549	1.00
275_A	303_F	1.529	1.00
77_G	81_E	1.521	1.00
272_V	306_K	1.520	1.00
191_A	206_V	1.520	1.00
78_Y	197_A	1.498	1.00
57_Q	61_A	1.494	1.00
376_K	380_T	1.489	1.00
47_E	221_N	1.485	1.00
294_I	398_A	1.484	1.00
62_K	427_Q	1.480	1.00
192_K	196_H	1.479	1.00
67_D	70_A	1.477	1.00
263_L	420_K	1.475	1.00
268_V	306_K	1.471	1.00
173_S	203_V	1.467	1.00
63_S	67_D	1.465	1.00
88_M	92_R	1.453	1.00
83_R	102_T	1.452	1.00
78_Y	193_A	1.443	1.00
126_K	462_P	1.437	1.00
274_A	414_F	1.430	1.00
310_R	313_Q	1.430	1.00
76_R	113_D	1.421	1.00
300_Y	369_V	1.419	1.00
397_E	401_M	1.414	1.00
343_E	346_K	1.411	1.00
293_I	387_A	1.410	1.00
294_I	392_A	1.408	1.00
301_D	391_K	1.407	1.00
27_L	34_V	1.400	1.00
315_P	323_K	1.397	1.00
275_A	293_I	1.396	1.00
73_Q	120_G	1.395	1.00
302_E	305_E	1.393	1.00
89_M	189_I	1.387	1.00
295_V	303_F	1.383	1.00
22_R	40_L	1.382	1.00
140_Y	426_L	1.379	1.00
84_D	88_M	1.377	1.00
216_D	242_I	1.367	1.00
118_Y	121_E	1.366	1.00
352_L	368_F	1.364	1.00
112_L	161_M	1.363	1.00
411_S	430_S	1.357	1.00
338_A	384_A	1.343	1.00
149_S	174_V	1.339	1.00
45_Q	48_D	1.332	1.00
240_G	456_V	1.330	1.00
88_M	320_T	1.330	1.00
264_S	420_K	1.328	1.00
335_I	339_L	1.324	1.00
396_Q	427_Q	1.319	1.00
226_L	251_A	1.315	1.00
82_N	189_I	1.307	1.00
332_E	335_I	1.303	1.00
335_I	358_R	1.296	1.00
43_G	217_G	1.296	1.00
301_D	305_E	1.289	1.00
341_I	382_L	1.285	1.00
394_S	397_E	1.284	1.00
348_D	376_K	1.276	1.00
28_N	31_D	1.275	1.00
304_V	308_T	1.274	1.00
336_E	340_E	1.273	1.00
77_G	113_D	1.272	1.00
160_S	176_H	1.268	1.00
392_A	401_M	1.265	1.00
263_L	424_F	1.264	1.00
315_P	325_V	1.249	1.00
263_L	392_A	1.249	1.00
261_A	398_A	1.247	1.00
57_Q	173_S	1.244	1.00
335_I	363_L	1.241	1.00
309_A	312_K	1.241	1.00
220_T	245_R	1.240	1.00
299_V	302_E	1.240	1.00
340_E	344_Q	1.239	1.00
91_A	101_S	1.236	1.00
76_R	80_H	1.228	1.00
40_L	210_D	1.225	1.00
463_W	466_E	1.225	1.00
306_K	310_R	1.223	1.00
462_P	466_E	1.217	1.00
296_H	394_S	1.214	1.00
374_N	379_Q	1.211	1.00
309_A	313_Q	1.203	1.00
51_D	55_K	1.201	1.00
312_K	354_V	1.200	1.00
399_I	424_F	1.194	1.00
191_A	204_L	1.192	1.00
350_I	368_F	1.184	1.00
141_R	471_T	1.178	1.00
296_H	299_V	1.176	1.00
88_M	98_I	1.174	1.00
216_D	238_H	1.164	1.00
317_G	324_T	1.163	1.00
304_V	369_V	1.158	1.00
138_K	422_E	1.157	1.00
50_F	223_I	1.156	1.00
63_S	71_V	1.155	1.00
425_A	474_I	1.151	1.00
396_Q	423_K	1.148	1.00
238_H	242_I	1.148	1.00
50_F	224_P	1.139	1.00
144_L	226_L	1.138	1.00
50_F	221_N	1.138	1.00
307_F	387_A	1.129	1.00
74_K	78_Y	1.122	1.00
373_N	404_D	1.120	1.00
24_E	40_L	1.119	1.00
411_S	433_T	1.117	1.00
91_A	319_Q	1.112	1.00
202_G	205_N	1.110	1.00
234_A	238_H	1.108	1.00
303_F	307_F	1.107	1.00
421_G	435_V	1.105	1.00
32_Q	361_N	1.099	1.00
359_V	364_T	1.098	1.00
46_L	214_I	1.098	1.00
396_Q	400_D	1.094	1.00
52_I	205_N	1.093	1.00
463_W	471_T	1.091	1.00
304_V	353_A	1.090	1.00
180_I	212_K	1.088	1.00
260_F	290_I	1.079	1.00
40_L	213_E	1.076	1.00
192_K	195_E	1.076	1.00
180_I	210_D	1.076	1.00
73_Q	117_T	1.069	1.00
188_T	208_L	1.067	1.00
36_T	184_I	1.066	1.00
240_G	250_M	1.065	1.00
235_V	238_H	1.064	1.00
379_Q	406_E	1.061	1.00
442_D	445_N	1.058	1.00
164_I	204_L	1.057	1.00
335_I	361_N	1.055	1.00
75_A	199_L	1.054	1.00
126_K	463_W	1.054	1.00
75_A	193_A	1.053	1.00
449_G	458_R	1.052	1.00
148_S	218_M	1.049	1.00
458_R	470_V	1.048	1.00
312_K	364_T	1.048	1.00
148_S	224_P	1.046	1.00
395_D	424_F	1.046	1.00
194_F	204_L	1.041	1.00
261_A	424_F	1.040	1.00
164_I	174_V	1.033	1.00
399_I	427_Q	1.031	1.00
28_N	318_D	1.029	1.00
267_D	416_S	1.028	1.00
217_G	221_N	1.027	1.00
267_D	270_R	1.023	1.00
237_R	247_F	1.022	1.00
149_S	228_S	1.022	1.00
308_T	354_V	1.019	1.00
82_N	192_K	1.019	1.00
75_A	112_L	1.019	1.00
348_D	375_S	1.016	1.00
69_K	120_G	1.016	1.00
379_Q	404_D	1.016	1.00
392_A	398_A	1.007	1.00
417_D	420_K	1.007	1.00
345_A	368_F	0.994	1.00
54_Q	58_K	0.992	1.00
146_V	173_S	0.990	1.00
276_I	310_R	0.989	1.00
270_R	274_A	0.988	1.00
56_A	173_S	0.988	1.00
261_A	402_A	0.984	1.00
86_I	189_I	0.981	1.00
30_Y	319_Q	0.979	1.00
108_T	161_M	0.979	1.00
73_Q	116_M	0.979	1.00
43_G	213_E	0.977	1.00
144_L	249_R	0.974	1.00
119_T	169_A	0.972	1.00
180_I	211_V	0.972	1.00
155_F	286_I	0.969	1.00
85_D	88_M	0.968	1.00
87_I	102_T	0.967	1.00
140_Y	474_I	0.965	1.00
451_N	470_V	0.965	1.00
58_K	429_D	0.965	1.00
344_Q	347_T	0.965	1.00
78_Y	82_N	0.957	1.00
58_K	400_D	0.954	1.00
43_G	47_E	0.954	1.00
92_R	320_T	0.950	1.00
81_E	196_H	0.949	1.00
191_A	195_E	0.945	1.00
340_E	343_E	0.937	1.00
400_D	404_D	0.931	1.00
314_L	326_V	0.931	1.00
147_I	226_L	0.926	1.00
341_I	344_Q	0.926	1.00
257_N	291_N	0.923	1.00
318_D	321_D	0.922	1.00
240_G	244_G	0.921	1.00
237_R	241_E	0.918	1.00
269_D	302_E	0.918	1.00
355_E	364_T	0.916	1.00
188_T	192_K	0.912	1.00
278_G	290_I	0.911	1.00
69_K	73_Q	0.911	1.00
371_A	375_S	0.911	1.00
412_A	438_Q	0.910	1.00
48_D	52_I	0.907	1.00
108_T	157_M	0.906	1.00
142_L	426_L	0.906	1.00
28_N	92_R	0.903	1.00
268_V	272_V	0.902	1.00
259_P	411_S	0.902	1.00
355_E	366_Y	0.900	1.00
70_A	74_K	0.900	1.00
27_L	361_N	0.900	1.00
65_T	69_K	0.899	1.00
181_Q	333_R	0.895	1.00
225_R	429_D	0.892	1.00
260_F	414_F	0.891	1.00
61_A	429_D	0.890	1.00
86_I	193_A	0.889	1.00
422_E	426_L	0.887	1.00
338_A	386_I	0.885	1.00
300_Y	389_I	0.882	1.00
137_N	446_I	0.879	1.00
142_L	451_N	0.879	1.00
94_T	182_T	0.878	1.00
30_Y	362_V	0.878	1.00
188_T	206_V	0.875	1.00
82_N	193_A	0.874	1.00
279_K	291_N	0.872	1.00
46_L	148_S	0.863	1.00
301_D	304_V	0.863	1.00
62_K	426_L	0.862	1.00
123_G	126_K	0.861	1.00
263_L	415_T	0.859	1.00
138_K	476_I	0.859	1.00
96_G	104_E	0.859	1.00
263_L	395_D	0.857	1.00
390_I	401_M	0.856	1.00
446_I	473_W	0.854	1.00
170_L	469_T	0.853	1.00
76_R	116_M	0.851	1.00
336_E	339_L	0.849	1.00
341_I	376_K	0.848	1.00
146_V	224_P	0.845	1.00
58_K	62_K	0.844	1.00
240_G	243_A	0.843	1.00
44_K	48_D	0.843	1.00
79_L	108_T	0.842	1.00
346_K	368_F	0.839	1.00
227_I	243_A	0.831	1.00
338_A	382_L	0.828	1.00
41_A	45_Q	0.828	1.00
373_N	390_I	0.823	1.00
272_V	307_F	0.822	1.00
44_K	47_E	0.822	1.00
48_D	51_D	0.822	1.00
272_V	310_R	0.821	1.00
305_E	308_T	0.820	1.00
411_S	428_I	0.816	1.00
144_L	470_V	0.816	1.00
24_E	210_D	0.815	1.00
176_H	186_G	0.814	1.00
240_G	247_F	0.810	1.00
249_R	470_V	0.810	1.00
418_L	421_G	0.809	1.00
356_G	366_Y	0.808	1.00
212_K	216_D	0.808	1.00
333_R	336_E	0.808	1.00
69_K	116_M	0.807	1.00
167_A	174_V	0.806	1.00
232_S	235_V	0.806	1.00
53_A	205_N	0.805	1.00
56_A	203_V	0.804	1.00
166_P	464_V	0.802	1.00
73_Q	77_G	0.800	1.00
52_I	202_G	0.800	1.00
178_P	208_L	0.796	1.00
60_W	203_V	0.795	1.00
160_S	164_I	0.788	1.00
342_I	386_I	0.785	1.00
80_H	83_R	0.784	1.00
350_I	375_S	0.784	1.00
413_V	424_F	0.783	1.00
32_Q	332_E	0.782	1.00
349_G	375_S	0.780	1.00
272_V	303_F	0.779	1.00
92_R	184_I	0.779	1.00
144_L	172_N	0.779	1.00
163_S	459_F	0.779	1.00
236_G	254_L	0.777	1.00
399_I	403_N	0.776	1.00
271_A	275_A	0.776	1.00
161_M	190_I	0.774	1.00
233_T	453_A	0.771	1.00
430_S	433_T	0.770	1.00
262_V	303_F	0.769	1.00
209_T	214_I	0.769	1.00
268_V	299_V	0.767	1.00
91_A	98_I	0.766	1.00
392_A	397_E	0.765	1.00
35_I	92_R	0.765	1.00
237_R	245_R	0.763	1.00
27_L	32_Q	0.763	1.00
217_G	220_T	0.762	1.00
307_F	367_V	0.762	1.00
55_K	59_E	0.761	1.00
55_K	58_K	0.761	1.00
219_L	239_I	0.758	1.00
71_V	197_A	0.758	1.00
219_L	242_I	0.756	1.00
94_T	330_I	0.756	1.00
199_L	203_V	0.755	1.00
236_G	252_L	0.752	1.00
398_A	401_M	0.751	1.00
157_M	185_S	0.750	1.00
99_I	325_V	0.749	1.00
41_A	49_A	0.748	1.00
316_Y	359_V	0.746	1.00
242_I	245_R	0.746	1.00
72_L	169_A	0.745	1.00
66_E	120_G	0.745	1.00
227_I	239_I	0.744	1.00
259_P	402_A	0.744	1.00
80_H	106_E	0.743	1.00
369_V	391_K	0.739	1.00
269_D	310_R	0.738	1.00
337_K	340_E	0.738	1.00
243_A	250_M	0.736	1.00
296_H	395_D	0.734	1.00
300_Y	370_G	0.731	1.00
58_K	61_A	0.730	1.00
59_E	63_S	0.728	1.00
28_N	320_T	0.727	1.00
53_A	173_S	0.727	1.00
98_I	320_T	0.726	1.00
87_I	98_I	0.725	1.00
229_F	235_V	0.724	1.00
149_S	163_S	0.720	1.00
219_L	227_I	0.719	1.00
338_A	363_L	0.718	1.00
314_L	325_V	0.717	1.00
341_I	380_T	0.716	1.00
144_L	225_R	0.714	1.00
102_T	322_P	0.709	1.00
418_L	476_I	0.709	1.00
160_S	186_G	0.705	1.00
137_N	473_W	0.704	1.00
181_Q	330_I	0.704	1.00
311_V	354_V	0.703	1.00
148_S	227_I	0.702	1.00
176_H	204_L	0.701	1.00
271_A	303_F	0.699	1.00
258_N	291_N	0.699	1.00
346_K	357_K	0.699	1.00
308_T	311_V	0.698	1.00
87_I	91_A	0.697	1.00
89_M	184_I	0.697	1.00
418_L	422_E	0.697	1.00
84_D	98_I	0.695	1.00
416_S	419_E	0.693	1.00
23_T	39_S	0.690	1.00
61_A	427_Q	0.687	1.00
54_Q	57_Q	0.684	1.00
151_S	160_S	0.683	1.00
283_Q	326_V	0.681	1.00
295_V	299_V	0.681	1.00
22_R	213_E	0.681	1.00
276_I	307_F	0.680	1.00
241_E	244_G	0.679	1.00
130_S	137_N	0.678	1.00
60_W	71_V	0.678	1.00
28_N	33_S	0.675	1.00
435_V	476_I	0.673	1.00
199_L	204_L	0.672	1.00
331_N	334_Q	0.671	1.00
275_A	307_F	0.670	1.00
46_L	217_G	0.670	1.00
85_D	192_K	0.669	1.00
334_Q	337_K	0.669	1.00
60_W	168_I	0.666	1.00
79_L	109_I	0.665	1.00
262_V	271_A	0.664	1.00
272_V	276_I	0.664	1.00
83_R	87_I	0.663	1.00
466_E	471_T	0.662	1.00
65_T	119_T	0.662	1.00
249_R	467_E	0.661	1.00
276_I	314_L	0.661	1.00
466_E	469_T	0.658	1.00
268_V	302_E	0.655	1.00
76_R	109_I	0.655	1.00
77_G	80_H	0.655	1.00
401_M	404_D	0.655	1.00
140_Y	472_K	0.655	1.00
67_D	71_V	0.654	1.00
270_R	273_D	0.653	1.00
90_I	93_E	0.653	1.00
265_D	415_T	0.652	1.00
46_L	50_F	0.650	1.00
263_L	296_H	0.649	1.00
136_T	422_E	0.648	1.00
429_D	451_N	0.648	1.00
321_D	324_T	0.647	1.00
335_I	359_V	0.647	1.00
373_N	378_A	0.647	1.00
172_N	469_T	0.646	1.00
137_N	475_S	0.645	1.00
270_R	416_S	0.643	1.00
294_I	378_A	0.641	1.00
52_I	201_A	0.640	1.00
307_F	389_I	0.636	1.00
332_E	358_R	0.636	1.00
294_I	373_N	0.635	1.00
61_A	142_L	0.635	1.00
122_L	469_T	0.634	1.00
47_E	223_I	0.634	1.00
213_E	216_D	0.633	1.00
74_K	197_A	0.632	1.00
56_A	59_E	0.631	1.00
311_V	314_L	0.631	1.00
194_F	199_L	0.631	1.00
348_D	374_N	0.631	1.00
316_Y	326_V	0.630	1.00
61_A	143_P	0.629	1.00
59_E	62_K	0.629	1.00
160_S	190_I	0.627	1.00
425_A	435_V	0.627	1.00
293_I	303_F	0.626	1.00
422_E	476_I	0.624	1.00
49_A	207_M	0.624	1.00
148_S	215_G	0.623	1.00
122_L	465_V	0.623	1.00
58_K	427_Q	0.623	1.00
394_S	400_D	0.622	1.00
333_R	337_K	0.621	1.00
39_S	208_L	0.620	1.00
96_G	100_K	0.620	1.00
318_D	324_T	0.619	1.00
395_D	399_I	0.619	1.00
26_I	36_T	0.619	1.00
265_D	416_S	0.616	1.00
26_I	93_E	0.615	1.00
211_V	215_G	0.614	1.00
356_G	364_T	0.613	1.00
363_L	366_Y	0.612	1.00
251_A	467_E	0.610	1.00
415_T	420_K	0.607	1.00
105_L	109_I	0.606	1.00
421_G	425_A	0.605	1.00
288_M	442_D	0.605	1.00
240_G	252_L	0.604	1.00
190_I	194_F	0.604	1.00
43_G	220_T	0.601	1.00
233_T	237_R	0.600	1.00
212_K	238_H	0.600	1.00
189_I	193_A	0.598	1.00
90_I	185_S	0.597	1.00
79_L	112_L	0.596	1.00
51_D	54_Q	0.595	1.00
419_E	422_E	0.595	1.00
91_A	320_T	0.595	1.00
78_Y	198_G	0.595	1.00
52_I	56_A	0.595	1.00
180_I	337_K	0.593	1.00
163_S	228_S	0.593	1.00
269_D	309_A	0.593	1.00
345_A	382_L	0.593	1.00
371_A	378_A	0.592	1.00
114_E	118_Y	0.591	1.00
342_I	368_F	0.591	1.00
329_L	334_Q	0.591	1.00
316_Y	325_V	0.589	1.00
419_E	423_K	0.589	1.00
164_I	176_H	0.588	1.00
279_K	387_A	0.588	1.00
180_I	238_H	0.585	1.00
265_D	417_D	0.585	1.00
399_I	423_K	0.585	1.00
382_L	386_I	0.584	1.00
90_I	101_S	0.584	1.00
88_M	91_A	0.583	1.00
373_N	400_D	0.583	1.00
295_V	300_Y	0.582	1.00
65_T	169_A	0.581	1.00
278_G	438_Q	0.580	1.00
339_L	346_K	0.576	1.00
354_V	367_V	0.576	1.00
358_R	364_T	0.575	1.00
87_I	105_L	0.574	1.00
147_I	172_N	0.574	1.00
35_I	184_I	0.573	1.00
90_I	104_E	0.572	1.00
71_V	198_G	0.571	1.00
268_V	303_F	0.571	1.00
66_E	70_A	0.571	1.00
146_V	225_R	0.570	1.00
86_I	157_M	0.570	1.00
342_I	366_Y	0.569	1.00
117_T	120_G	0.569	1.00
96_G	155_F	0.568	1.00
295_V	389_I	0.566	1.00
413_V	435_V	0.566	1.00
370_G	391_K	0.565	1.00
138_K	474_I	0.565	1.00
38_A	183_A	0.565	1.00
175_V	205_N	0.564	1.00
432_M	441_N	0.564	1.00
260_F	412_A	0.564	1.00
170_L	465_V	0.564	1.00
339_L	342_I	0.564	1.00
70_A	73_Q	0.561	1.00
49_A	205_N	0.560	1.00
371_A	377_I	0.559	1.00
54_Q	146_V	0.559	1.00
268_V	271_A	0.558	1.00
250_M	456_V	0.558	1.00
76_R	112_L	0.557	1.00
79_L	157_M	0.555	1.00
341_I	345_A	0.555	1.00
41_A	207_M	0.555	1.00
260_F	293_I	0.555	1.00
226_L	467_E	0.554	1.00
22_R	42_T	0.554	1.00
413_V	421_G	0.553	1.00
168_I	204_L	0.553	1.00
118_Y	462_P	0.552	1.00
215_G	219_L	0.549	1.00
395_D	427_Q	0.549	1.00
402_A	428_I	0.547	1.00
352_L	366_Y	0.544	1.00
105_L	157_M	0.543	1.00
65_T	123_G	0.542	1.00
434_H	437_D	0.540	1.00
273_D	277_F	0.540	1.00
293_I	389_I	0.539	1.00
53_A	175_V	0.539	1.00
286_I	289_I	0.539	1.00
142_L	429_D	0.537	1.00
308_T	367_V	0.536	1.00
173_S	205_N	0.536	1.00
398_A	402_A	0.533	1.00
106_E	109_I	0.531	1.00
115_A	166_P	0.530	1.00
377_I	382_L	0.530	1.00
399_I	428_I	0.530	1.00
368_F	371_A	0.530	1.00
264_S	392_A	0.529	1.00
429_D	470_V	0.528	1.00
222_P	406_E	0.527	1.00
147_I	174_V	0.527	1.00
297_Q	300_Y	0.526	1.00
102_T	106_E	0.526	1.00
433_T	472_K	0.525	1.00
139_I	471_T	0.522	1.00
107_Q	158_N	0.521	1.00
158_N	162_R	0.521	1.00
424_F	428_I	0.521	1.00
209_T	215_G	0.520	1.00
38_A	184_I	0.519	1.00
337_K	341_I	0.519	1.00
353_A	370_G	0.518	1.00
348_D	372_D	0.517	1.00
94_T	282_H	0.517	1.00
258_N	410_S	0.516	1.00
43_G	216_D	0.516	1.00
228_S	468_F	0.515	1.00
53_A	146_V	0.515	1.00
266_A	271_A	0.514	1.00
75_A	78_Y	0.513	1.00
290_I	412_A	0.513	1.00
86_I	105_L	0.512	1.00
220_T	246_A	0.512	1.00
157_M	190_I	0.512	1.00
352_L	356_G	0.511	1.00
280_F	314_L	0.511	1.00
307_F	311_V	0.510	1.00
162_R	460_G	0.510	1.00
83_R	109_I	0.510	1.00
233_T	406_E	0.509	1.00
168_I	199_L	0.508	1.00
329_L	363_L	0.507	1.00
52_I	55_K	0.506	1.00
79_L	190_I	0.506	1.00
40_L	180_I	0.505	1.00
111_I	460_G	0.502	1.00
149_S	164_I	0.500	1.00
234_A	333_R	0.500	1.00
71_V	75_A	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1a4sA	4	0.9897	100	0.032	Contact Map
4qtoA	4	0.9938	100	0.032	Contact Map
4o5hA	4	0.9814	100	0.033	Contact Map
2d4eA	4	0.9918	100	0.035	Contact Map
4qf6A	4	0.9794	100	0.037	Contact Map
4yweA	5	0.9649	100	0.037	Contact Map
3ek1A	5	0.9835	100	0.038	Contact Map
3u4jA	4	0.9938	100	0.038	Contact Map
4jz6A	2	0.9897	100	0.038	Contact Map
3r31A	4	0.967	100	0.04	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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