GREMLIN Database
RRF - Ribosome-recycling factor
UniProt: P81101 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 185 (181)
Sequences: 3567 (2024)
Seq/√Len: 150.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
72_K96_N3.0451.00
121_A175_T2.9711.00
10_K166_E2.9351.00
161_Q165_D2.6781.00
139_L153_L2.5401.00
20_Y124_A2.5101.00
170_K173_S2.4471.00
61_E64_M2.3471.00
169_S173_S2.2671.00
20_Y24_L2.2301.00
158_E162_K2.1341.00
166_E170_K2.1061.00
107_E111_K1.9801.00
83_L90_T1.9771.00
143_E153_L1.9531.00
69_P78_I1.9291.00
121_A171_I1.9041.00
128_V171_I1.8731.00
75_I93_S1.8721.00
9_T135_A1.8531.00
176_K180_K1.8461.00
36_L102_I1.8391.00
173_S177_D1.8081.00
180_K184_E1.7861.00
7_T10_K1.7721.00
66_V97_M1.7401.00
14_E170_K1.7141.00
109_R112_E1.7111.00
136_N160_V1.6741.00
27_V117_V1.6671.00
10_K14_E1.6651.00
54_L74_A1.6581.00
41_T48_Q1.6471.00
155_A159_D1.5901.00
74_A77_D1.5891.00
58_N66_V1.5771.00
14_E167_Y1.5651.00
64_M101_A1.5531.00
44_Y49_T1.5501.00
11_E15_K1.5421.00
139_L160_V1.5341.00
133_R137_D1.5281.00
153_L157_T1.5181.00
40_V85_A1.4891.00
162_K165_D1.4831.00
143_E150_E1.4761.00
121_A125_K1.4691.00
79_E93_S1.4631.00
43_E48_Q1.4411.00
17_I174_V1.4251.00
176_K179_E1.4011.00
167_Y170_K1.3961.00
26_T39_K1.3781.00
89_L102_I1.3681.00
107_E183_M1.3631.00
5_V135_A1.3481.00
44_Y74_A1.3441.00
50_P53_Q1.3441.00
10_K167_Y1.3391.00
119_K123_E1.3281.00
21_Q174_V1.3141.00
8_Q12_K1.3091.00
148_I153_L1.2871.00
37_L65_L1.2871.00
173_S176_K1.2741.00
136_N140_K1.2731.00
14_E18_A1.2541.00
113_L182_I1.2341.00
24_L121_A1.2321.00
40_V81_A1.2261.00
12_K131_V1.2261.00
137_D141_K1.2191.00
135_A160_V1.2191.00
18_A21_Q1.2171.00
23_E120_Y1.2021.00
141_K145_N1.1981.00
10_K163_L1.1891.00
24_L174_V1.1881.00
27_V120_Y1.1821.00
152_E155_A1.1661.00
114_V179_E1.1411.00
117_V175_T1.1220.99
136_N157_T1.1170.99
59_V65_L1.1010.99
89_L100_I1.0960.99
44_Y71_D1.0950.99
13_M164_T1.0900.99
128_V164_T1.0880.99
124_A171_I1.0870.99
34_P57_I1.0700.99
54_L71_D1.0580.99
24_L175_T1.0570.99
21_Q170_K1.0490.99
71_D74_A1.0470.99
165_D169_S1.0300.99
105_L113_L1.0240.99
143_E146_G1.0000.99
6_L159_D0.9970.99
16_A131_V0.9940.99
149_T153_L0.9810.99
92_T101_A0.9810.99
118_K179_E0.9800.99
120_Y123_E0.9800.99
37_L67_I0.9750.99
63_R104_A0.9660.98
177_D180_K0.9620.98
5_V142_L0.9600.98
43_E77_D0.9470.98
5_V9_T0.9400.98
139_L156_S0.9310.98
16_A127_A0.9280.98
19_A23_E0.9200.98
87_L100_I0.9190.98
60_P66_V0.9130.98
20_Y175_T0.9100.98
55_S69_P0.9070.98
94_D99_R0.9030.98
142_L148_I0.8740.97
111_K183_M0.8740.97
15_K131_V0.8720.97
130_N133_R0.8710.97
146_G149_T0.8700.97
138_D141_K0.8610.97
117_V182_I0.8550.97
22_R25_A0.8530.97
128_V168_V0.8520.97
118_K175_T0.8450.96
19_A22_R0.8420.96
163_L167_Y0.8350.96
9_T13_M0.8340.96
49_T54_L0.8330.96
164_T168_V0.8320.96
127_A131_V0.8320.96
140_K157_T0.8270.96
137_D140_K0.8230.96
113_L116_V0.8220.96
34_P65_L0.8170.96
6_L163_L0.8160.96
9_T163_L0.8100.95
114_V183_M0.8090.95
37_L100_I0.8080.95
34_P59_V0.8070.95
79_E83_L0.8010.95
142_L145_N0.8000.95
109_R113_L0.7940.95
82_I89_L0.7920.95
125_K172_D0.7890.95
7_T11_E0.7830.95
43_E46_G0.7830.95
12_K134_D0.7830.95
20_Y117_V0.7770.94
59_V62_A0.7720.94
18_A22_R0.7710.94
59_V64_M0.7710.94
8_Q11_E0.7690.94
124_A127_A0.7670.94
42_V54_L0.7600.94
165_D168_V0.7550.93
68_T96_N0.7520.93
166_E169_S0.7520.93
142_L147_D0.7510.93
17_I170_K0.7490.93
13_M167_Y0.7470.93
54_L70_Y0.7470.93
6_L160_V0.7440.93
169_S172_D0.7390.93
105_L109_R0.7380.93
77_D80_K0.7330.92
21_Q25_A0.7230.92
142_L156_S0.7220.92
6_L156_S0.7180.92
26_T38_D0.7160.91
76_G84_K0.7140.91
16_A128_V0.7120.91
116_V120_Y0.7120.91
6_L10_K0.7080.91
162_K166_E0.7050.91
17_I128_V0.7020.91
26_T120_Y0.7010.91
60_P64_M0.6930.90
87_L90_T0.6790.89
76_G79_E0.6680.88
23_E123_E0.6660.88
56_S70_Y0.6650.88
154_R157_T0.6650.88
49_T53_Q0.6650.88
77_D84_K0.6570.88
20_Y174_V0.6560.87
24_L117_V0.6510.87
27_V113_L0.6440.86
150_E154_R0.6420.86
90_T101_A0.6400.86
167_Y176_K0.6390.86
7_T14_E0.6380.86
52_N70_Y0.6340.86
17_I21_Q0.6340.86
58_N68_T0.6320.85
38_D52_N0.6310.85
138_D142_L0.6260.85
149_T152_E0.6260.85
75_I94_D0.6220.85
40_V51_L0.6220.85
114_V175_T0.6210.84
19_A127_A0.6140.84
80_K84_K0.6120.84
113_L117_V0.6120.84
17_I167_Y0.6110.84
170_K174_V0.6100.83
66_V99_R0.6090.83
70_Y74_A0.6080.83
163_L166_E0.6080.83
17_I171_I0.6060.83
125_K168_V0.6050.83
154_R158_E0.6010.83
159_D163_L0.6010.83
16_A124_A0.5980.82
90_T100_I0.5910.81
16_A19_A0.5910.81
9_T131_V0.5910.81
159_D162_K0.5900.81
35_S65_L0.5830.81
67_I83_L0.5780.80
73_T76_G0.5780.80
42_V74_A0.5770.80
11_E14_E0.5760.80
116_V119_K0.5750.80
101_A104_A0.5740.80
63_R184_E0.5680.79
94_D97_M0.5650.78
14_E17_I0.5650.78
52_N71_D0.5650.78
170_K177_D0.5650.78
20_Y171_I0.5630.78
67_I78_I0.5610.78
133_R136_N0.5600.78
19_A37_L0.5590.78
21_Q177_D0.5570.78
89_L101_A0.5510.77
49_T71_D0.5490.77
114_V182_I0.5450.76
29_A33_N0.5450.76
14_E163_L0.5420.76
25_A90_T0.5390.75
73_T77_D0.5390.75
158_E161_Q0.5380.75
38_D70_Y0.5350.75
76_G92_T0.5330.74
148_I156_S0.5330.74
121_A172_D0.5320.74
37_L40_V0.5320.74
136_N139_L0.5310.74
36_L87_L0.5310.74
29_A63_R0.5300.74
37_L87_L0.5280.74
55_S74_A0.5260.73
44_Y48_Q0.5260.73
32_A102_I0.5220.73
56_S74_A0.5220.73
8_Q131_V0.5210.73
112_E116_V0.5210.73
119_K180_K0.5180.72
174_V177_D0.5170.72
79_E92_T0.5150.72
112_E119_K0.5130.72
69_P96_N0.5120.71
121_A124_A0.5100.71
118_K136_N0.5100.71
110_R182_I0.5070.71
125_K175_T0.5050.70
156_S159_D0.5050.70
114_V118_K0.5040.70
67_I101_A0.5000.70
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1is1A 1 1 100 -0.033 Contact Map
1dd5A 1 0.9946 100 -0.033 Contact Map
4kddA 1 0.9946 100 -0.033 Contact Map
1iseA 1 0.9946 100 -0.032 Contact Map
1eh1A 1 0.9946 100 -0.024 Contact Map
4gfqA 1 1 100 -0.02 Contact Map
1ge9A 1 0.9784 100 0.012 Contact Map
3lf9A 1 0.6108 100 0.475 Contact Map
1wihA 1 0.4432 100 0.496 Contact Map
3lhpS 1 0.627 99.9 0.534 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0082 seconds.