GREMLIN Database
EFG - Elongation factor G
UniProt: P80868 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 692 (680)
Sequences: 5391 (2729)
Seq/√Len: 104.7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
368_V374_A5.8131.00
490_K511_E4.1351.00
541_Q545_E4.0951.00
492_E507_H3.8441.00
487_T596_N3.6841.00
513_E562_K3.5701.00
228_K239_E3.5461.00
181_N207_A3.4831.00
133_F261_A3.3601.00
521_F541_Q3.3561.00
109_Q139_K3.2511.00
512_F563_A3.2311.00
257_L273_A3.1941.00
301_H306_E3.0181.00
241_K276_D3.0001.00
486_R676_E2.9911.00
327_F376_A2.9781.00
520_G560_D2.9721.00
610_I665_G2.9681.00
546_D581_K2.9311.00
133_F259_G2.9231.00
335_D367_T2.9061.00
605_K670_H2.8891.00
590_N594_K2.8811.00
107_D110_S2.8551.00
50_M68_T2.8411.00
162_I257_L2.7871.00
312_A325_T2.7451.00
511_E566_F2.7131.00
526_A564_K2.7111.00
513_E564_K2.6821.00
558_L592_V2.6311.00
106_L116_T2.6191.00
27_T79_I2.6001.00
425_A464_M2.5991.00
634_A639_Q2.5571.00
236_T239_E2.5521.00
488_G513_E2.5381.00
182_V196_A2.5161.00
408_D450_S2.5091.00
518_G560_D2.5091.00
436_F449_I2.4961.00
539_A577_E2.4821.00
621_D653_Y2.4741.00
329_V368_V2.4641.00
206_Q209_E2.4621.00
510_I587_A2.4481.00
204_K208_E2.4431.00
201_E204_K2.4401.00
149_G153_D2.4141.00
577_E581_K2.3781.00
524_E562_K2.3681.00
677_V685_I2.2881.00
323_K431_E2.2781.00
180_E237_I2.2411.00
227_D231_E2.1761.00
644_M673_H2.1641.00
414_K471_E2.1541.00
146_Y150_T2.1431.00
490_K566_F2.1271.00
108_A137_M2.0931.00
176_I203_Y2.0781.00
511_E564_K2.0781.00
509_W566_F2.0711.00
288_K297_E2.0681.00
222_D246_K2.0491.00
414_K473_N2.0421.00
522_E562_K2.0381.00
465_K471_E2.0301.00
622_I627_G2.0241.00
206_Q210_L2.0221.00
436_F460_I2.0131.00
677_V681_V2.0111.00
343_S389_C2.0091.00
145_L206_Q1.9971.00
16_M104_A1.9961.00
494_K505_F1.9781.00
507_H569_S1.9771.00
628_R675_E1.9571.00
608_V622_I1.9571.00
132_V151_L1.9561.00
308_F340_V1.9541.00
511_E526_A1.9531.00
187_E195_D1.9511.00
13_I77_V1.9311.00
527_I531_V1.9261.00
517_E560_D1.9121.00
327_F374_A1.9001.00
209_E213_S1.8831.00
43_T48_S1.8821.00
300_R306_E1.8731.00
333_T367_T1.8591.00
516_E519_A1.8571.00
521_F545_E1.8521.00
147_S150_T1.8441.00
404_E437_R1.8191.00
544_L584_A1.8111.00
329_V374_A1.8071.00
160_H253_F1.7991.00
607_E640_V1.7941.00
605_K642_R1.7791.00
548_L561_I1.7741.00
430_A436_F1.7721.00
488_G511_E1.7561.00
303_S306_E1.7551.00
588_L592_V1.7511.00
671_M674_Y1.7511.00
412_E473_N1.7401.00
182_V198_E1.7351.00
291_R298_I1.7241.00
345_K383_T1.7181.00
180_E196_A1.7031.00
298_I395_V1.7001.00
164_L203_Y1.6941.00
184_Y269_L1.6921.00
181_N208_E1.6891.00
235_I243_G1.6811.00
519_A522_E1.6801.00
510_I544_L1.6741.00
576_N579_A1.6601.00
215_I240_L1.6561.00
34_T70_A1.6511.00
679_K683_E1.6491.00
210_L213_S1.6451.00
152_R213_S1.6431.00
521_F548_L1.6311.00
131_I278_L1.6011.00
492_E509_W1.5911.00
335_D338_S1.5891.00
644_M672_D1.5831.00
52_W64_T1.5781.00
633_E642_R1.5751.00
605_K672_D1.5741.00
347_K381_D1.5701.00
224_E227_D1.5681.00
185_F197_K1.5651.00
218_V247_G1.5631.00
486_R596_N1.5621.00
37_I49_Q1.5591.00
544_L563_A1.5571.00
439_Q450_S1.5571.00
16_M102_A1.5491.00
606_V650_M1.5311.00
199_I207_A1.5301.00
379_L382_T1.5221.00
489_A595_C1.5201.00
65_S80_I1.5201.00
356_Q365_I1.5161.00
68_T358_H1.5101.00
341_K394_L1.5091.00
598_V676_E1.5061.00
494_K507_H1.5041.00
145_L210_L1.5011.00
515_N519_A1.5011.00
107_D147_S1.4721.00
408_D448_I1.4671.00
354_I376_A1.4601.00
512_F591_A1.4561.00
490_K509_W1.4561.00
70_A79_I1.4491.00
9_K75_Y1.4461.00
558_L588_L1.4451.00
491_V590_N1.4411.00
336_S366_S1.4391.00
119_V122_Q1.4351.00
590_N593_S1.4341.00
242_A246_K1.4271.00
630_E644_M1.4231.00
344_T386_D1.4221.00
228_K236_T1.4181.00
223_E227_D1.4101.00
292_P296_E1.4031.00
228_K233_E1.4011.00
12_N78_N1.4011.00
481_Y648_A1.4011.00
486_R598_V1.3981.00
183_A200_P1.3971.00
334_L351_V1.3921.00
50_M66_A1.3871.00
493_G506_G1.3871.00
310_A327_F1.3841.00
108_A134_V1.3821.00
223_E252_E1.3791.00
309_S397_L1.3771.00
524_E564_K1.3771.00
341_K346_G1.3771.00
117_E664_R1.3761.00
166_I176_I1.3751.00
14_G99_L1.3721.00
291_R294_T1.3701.00
461_V474_V1.3701.00
148_V161_A1.3681.00
612_E639_Q1.3671.00
493_G586_M1.3661.00
632_M639_Q1.3641.00
15_I27_T1.3611.00
90_V435_T1.3601.00
187_E193_R1.3601.00
548_L588_L1.3550.99
409_V474_V1.3480.99
106_L151_L1.3480.99
178_L181_N1.3480.99
540_V565_L1.3450.99
75_Y275_L1.3410.99
415_S418_D1.3400.99
198_E201_E1.3390.99
618_I661_T1.3380.99
145_L164_L1.3360.99
181_N199_I1.3280.99
312_A382_T1.3270.99
635_R638_A1.3230.99
37_I40_I1.3160.99
124_T130_R1.3140.99
241_K277_Y1.3130.99
365_I368_V1.3110.99
300_R395_V1.3100.99
218_V221_L1.3090.99
333_T369_Y1.3040.99
515_N522_E1.3030.99
443_E482_R1.3010.99
532_V565_L1.2920.99
462_D466_R1.2870.99
214_L218_V1.2810.99
353_R364_E1.2790.99
682_A686_I1.2770.99
9_K74_G1.2700.99
289_G292_P1.2680.99
26_T261_A1.2590.99
525_N534_R1.2530.99
164_L207_A1.2520.99
517_E520_G1.2490.99
116_T132_V1.2480.99
106_L132_V1.2440.99
173_E185_F1.2440.99
107_D150_T1.2420.99
449_I460_I1.2360.99
290_T294_T1.2310.99
607_E642_R1.2290.99
26_T105_V1.2250.99
164_L210_L1.2240.99
493_G496_V1.2220.99
246_K250_N1.2210.99
11_R281_P1.2170.99
430_A449_I1.2120.99
523_F565_L1.2080.99
635_R640_V1.2080.99
208_E212_N1.2060.99
561_I588_L1.2050.99
605_K644_M1.2020.99
422_M464_M1.2010.99
454_E652_G1.1990.99
218_V225_L1.1980.99
615_M641_V1.1980.99
661_T665_G1.1930.99
104_A132_V1.1900.99
107_D139_K1.1900.99
599_L685_I1.1890.99
656_A660_N1.1880.99
485_F597_P1.1880.99
211_R215_I1.1870.99
533_P570_Y1.1860.99
162_I273_A1.1760.99
27_T50_M1.1730.99
340_V351_V1.1720.99
188_D192_T1.1700.99
148_V256_V1.1690.98
151_L256_V1.1550.98
441_N444_T1.1550.98
184_Y196_A1.1480.98
48_S57_Q1.1450.98
390_D393_D1.1400.98
515_N560_D1.1340.98
52_W316_M1.1330.98
101_G278_L1.1310.98
166_I183_A1.1310.98
619_M623_T1.1290.98
72_W272_D1.1280.98
26_T270_V1.1270.98
349_E382_T1.1230.98
622_I645_V1.1220.98
323_K435_T1.1190.98
650_M669_M1.1180.98
166_I203_Y1.1170.98
316_M326_F1.1140.98
508_V532_V1.1120.98
491_V594_K1.1120.98
585_S589_K1.1110.98
149_G152_R1.0940.98
180_E241_K1.0940.98
368_V376_A1.0930.98
308_F334_L1.0920.98
286_A289_G1.0910.98
17_A21_A1.0870.98
525_N528_V1.0840.98
71_Q76_R1.0800.97
280_A283_D1.0750.97
110_S150_T1.0660.97
218_V240_L1.0650.97
58_E466_R1.0640.97
274_V278_L1.0640.97
93_E125_T1.0610.97
145_L149_G1.0600.97
604_M647_L1.0560.97
355_L364_E1.0560.97
526_A566_F1.0530.97
485_F592_V1.0510.97
498_Q503_G1.0510.97
219_C243_G1.0490.97
582_V585_S1.0490.97
327_F334_L1.0490.97
235_I240_L1.0470.97
491_V591_A1.0470.97
33_Y268_Q1.0460.97
16_M96_L1.0460.97
179_V277_Y1.0450.97
308_F329_V1.0420.97
334_L340_V1.0420.97
657_L661_T1.0390.97
553_L686_I1.0380.97
626_R649_E1.0360.97
235_I239_E1.0330.97
55_Q462_D1.0290.97
606_V643_A1.0260.97
123_A130_R1.0250.97
150_T154_R1.0230.96
495_F586_M1.0230.96
160_H214_L1.0150.96
50_M62_T1.0140.96
309_S331_S1.0140.96
463_R467_E1.0120.96
327_F368_V1.0110.96
10_T76_R1.0070.96
618_I657_L0.9990.96
76_R356_Q0.9990.96
610_I618_I0.9980.96
515_N562_K0.9970.96
237_I241_K0.9950.96
285_A289_G0.9900.96
502_R576_N0.9900.96
137_M168_A0.9890.96
525_N537_I0.9870.96
645_V653_Y0.9860.96
245_R249_L0.9850.96
575_S580_F0.9850.96
288_K299_E0.9840.96
245_R283_D0.9810.96
125_T401_E0.9800.96
493_G509_W0.9760.95
304_D333_T0.9730.95
178_L211_R0.9720.95
412_E475_G0.9710.95
506_G569_S0.9710.95
104_A116_T0.9700.95
342_N382_T0.9700.95
412_E446_Q0.9700.95
604_M669_M0.9680.95
512_F544_L0.9680.95
601_E626_R0.9660.95
73_K276_D0.9640.95
205_E208_E0.9630.95
609_V640_V0.9610.95
93_E122_Q0.9590.95
599_L682_A0.9580.95
527_I530_G0.9550.95
134_V147_S0.9530.95
617_D632_M0.9530.95
519_A560_D0.9500.95
135_N261_A0.9460.95
446_Q475_G0.9440.95
509_W567_D0.9430.94
186_Y194_S0.9390.94
219_C235_I0.9360.94
205_E209_E0.9360.94
503_G574_D0.9340.94
104_A119_V0.9330.94
355_L377_V0.9310.94
30_I70_A0.9300.94
76_R372_D0.9270.94
508_V584_A0.9260.94
615_M632_M0.9260.94
588_L597_P0.9250.94
132_V254_Y0.9250.94
59_R462_D0.9220.94
545_E549_E0.9190.94
568_G571_H0.9190.94
621_D660_N0.9160.94
628_R644_M0.9130.93
25_T43_T0.9120.93
144_F161_A0.9100.93
100_D328_R0.9060.93
365_I374_A0.9050.93
179_V237_I0.9040.93
191_G268_Q0.9040.93
531_V567_D0.9030.93
324_L375_A0.9010.93
158_N217_A0.9010.93
52_W360_N0.9000.93
539_A581_K0.9000.93
112_V116_T0.9000.93
578_M582_V0.8990.93
608_V645_V0.8980.93
510_I565_L0.8940.93
71_Q74_G0.8940.93
429_L464_M0.8920.93
304_D369_Y0.8920.93
80_I99_L0.8910.93
510_I563_A0.8900.93
313_F373_I0.8900.93
238_D242_A0.8870.92
326_F357_M0.8870.92
351_V376_A0.8850.92
184_Y194_S0.8820.92
244_I253_F0.8820.92
54_E57_Q0.8800.92
247_G253_F0.8790.92
73_K275_L0.8790.92
137_M142_A0.8770.92
53_M64_T0.8730.92
203_Y207_A0.8730.92
609_V635_R0.8720.92
42_E45_E0.8720.92
495_F502_R0.8690.92
446_Q477_P0.8650.92
537_I565_L0.8650.92
494_K569_S0.8640.91
162_I244_I0.8640.91
164_L206_Q0.8620.91
315_V325_T0.8610.91
90_V402_F0.8610.91
73_K272_D0.8610.91
103_V270_V0.8600.91
179_V240_L0.8590.91
156_Q637_N0.8580.91
516_E520_G0.8570.91
558_L561_I0.8550.91
178_L207_A0.8530.91
512_F592_V0.8510.91
493_G497_R0.8500.91
515_N520_G0.8500.91
260_S263_K0.8480.91
221_L247_G0.8480.91
546_D577_E0.8470.91
103_V274_V0.8460.91
547_A588_L0.8440.90
621_D625_R0.8430.90
622_I641_V0.8430.90
493_G507_H0.8410.90
356_Q363_E0.8400.90
44_H48_S0.8390.90
13_I274_V0.8390.90
335_D366_S0.8380.90
461_V465_K0.8380.90
368_V372_D0.8340.90
508_V587_A0.8320.90
532_V537_I0.8280.90
621_D656_A0.8270.90
137_M172_F0.8260.90
221_L243_G0.8260.90
593_S597_P0.8250.89
37_I43_T0.8250.89
489_A591_A0.8240.89
438_T447_T0.8240.89
31_L49_Q0.8240.89
348_R391_E0.8230.89
17_A20_D0.8220.89
132_V256_V0.8210.89
223_E226_M0.8210.89
306_E331_S0.8190.89
571_H574_D0.8180.89
224_E228_K0.8150.89
98_V313_F0.8140.89
407_I651_F0.8130.89
203_Y206_Q0.8130.89
493_G590_N0.8120.89
356_Q368_V0.8120.89
70_A77_V0.8090.89
503_G529_G0.8080.88
340_V388_L0.8060.88
160_H244_I0.8040.88
343_S396_I0.7950.88
527_I537_I0.7940.88
63_I459_I0.7940.88
201_E205_E0.7900.87
647_L669_M0.7900.87
220_E226_M0.7870.87
516_E560_D0.7860.87
120_W130_R0.7840.87
480_A674_Y0.7830.87
624_S656_A0.7830.87
543_G547_A0.7830.87
498_Q529_G0.7810.87
173_E202_E0.7790.87
568_G574_D0.7770.86
172_F175_I0.7760.86
329_V369_Y0.7760.86
30_I34_T0.7750.86
578_M581_K0.7750.86
82_T92_V0.7740.86
583_A587_A0.7730.86
515_N518_G0.7720.86
357_M375_A0.7720.86
300_R309_S0.7710.86
487_T514_P0.7700.86
289_G300_R0.7690.86
284_V302_S0.7690.86
100_D129_P0.7680.86
41_G46_G0.7670.86
497_R501_G0.7650.86
28_E48_S0.7640.86
215_I229_Y0.7640.86
496_V503_G0.7600.85
57_Q360_N0.7590.85
160_H217_A0.7580.85
152_R159_A0.7570.85
609_V666_T0.7570.85
546_D585_S0.7560.85
379_L388_L0.7560.85
284_V287_I0.7550.85
425_A429_L0.7530.85
105_V135_N0.7530.85
538_P542_A0.7530.85
528_V534_R0.7520.85
504_Q576_N0.7520.85
163_Q257_L0.7500.85
54_E58_E0.7490.84
48_S68_T0.7490.84
525_N541_Q0.7480.84
528_V531_V0.7480.84
163_Q258_V0.7470.84
224_E239_E0.7440.84
216_E220_E0.7440.84
27_T68_T0.7430.84
228_K235_I0.7420.84
33_Y264_N0.7420.84
51_D56_E0.7410.84
430_A438_T0.7400.84
167_G172_F0.7380.84
181_N211_R0.7380.84
145_L203_Y0.7370.83
15_I103_V0.7360.83
496_V507_H0.7360.83
93_E119_V0.7350.83
152_R158_N0.7350.83
310_A388_L0.7330.83
680_S683_E0.7330.83
503_G573_V0.7310.83
611_P664_R0.7300.83
439_Q448_I0.7290.83
552_V558_L0.7290.83
290_T295_N0.7290.83
44_H262_F0.7280.83
41_G45_E0.7280.83
554_A686_I0.7270.83
251_V254_Y0.7260.83
592_V597_P0.7260.83
143_D146_Y0.7260.83
606_V669_M0.7250.82
185_F195_D0.7240.82
525_N532_V0.7230.82
454_E655_T0.7190.82
529_G567_D0.7180.82
508_V565_L0.7180.82
132_V147_S0.7170.82
498_Q501_G0.7170.82
291_R296_E0.7170.82
50_M358_H0.7170.82
518_G521_F0.7160.82
429_L460_I0.7150.82
36_R358_H0.7130.81
508_V540_V0.7120.81
273_A277_Y0.7120.81
315_V384_T0.7110.81
33_Y191_G0.7110.81
512_F561_I0.7100.81
167_G173_E0.7080.81
645_V650_M0.7070.81
285_A302_S0.7070.81
633_E640_V0.7060.81
16_M400_M0.7060.81
102_A128_V0.7060.81
484_T600_L0.7060.81
423_G447_T0.7050.81
581_K585_S0.7040.81
503_G530_G0.7030.80
540_V543_G0.7010.80
25_T40_I0.7010.80
644_M675_E0.7010.80
41_G47_A0.7000.80
532_V540_V0.6990.80
527_I532_V0.6990.80
339_Y348_R0.6980.80
303_S307_P0.6970.80
183_A197_K0.6970.80
492_E496_V0.6960.80
240_L247_G0.6950.80
652_G656_A0.6940.80
582_V586_M0.6930.80
178_L214_L0.6930.80
532_V568_G0.6930.80
369_Y372_D0.6920.79
552_V592_V0.6910.79
26_T267_V0.6900.79
217_A220_E0.6900.79
107_D136_K0.6890.79
460_I464_M0.6890.79
69_T76_R0.6890.79
318_D362_R0.6880.79
336_S364_E0.6880.79
97_R122_Q0.6860.79
110_S147_S0.6860.79
65_S95_S0.6850.79
167_G174_G0.6830.79
529_G571_H0.6820.78
547_A558_L0.6810.78
55_Q59_R0.6810.78
492_E590_N0.6810.78
36_R68_T0.6810.78
521_F561_I0.6800.78
97_R311_L0.6800.78
300_R393_D0.6790.78
349_E380_K0.6790.78
530_G533_P0.6790.78
293_D296_E0.6780.78
300_R331_S0.6760.78
188_D193_R0.6750.78
451_G457_L0.6750.78
496_V499_S0.6740.78
491_V595_C0.6740.78
493_G508_V0.6730.78
539_A542_A0.6730.78
78_N372_D0.6730.78
109_Q262_F0.6730.78
42_E48_S0.6720.77
354_I365_I0.6720.77
498_Q530_G0.6710.77
146_Y149_G0.6710.77
90_V399_S0.6700.77
682_A685_I0.6690.77
7_L10_T0.6680.77
320_Y323_K0.6670.77
500_G503_G0.6670.77
574_D580_F0.6670.77
615_M619_M0.6650.77
97_R400_M0.6640.77
321_V355_L0.6640.77
308_F333_T0.6640.77
178_L210_L0.6620.76
310_A334_L0.6620.76
563_A588_L0.6610.76
52_W359_A0.6610.76
433_D456_H0.6610.76
501_G504_Q0.6600.76
542_A545_E0.6600.76
615_M639_Q0.6580.76
515_N524_E0.6580.76
612_E637_N0.6570.76
216_E229_Y0.6570.76
568_G580_F0.6570.76
113_E609_V0.6570.76
459_I462_D0.6570.76
652_G655_T0.6560.76
109_Q146_Y0.6550.76
259_G270_V0.6550.76
584_A588_L0.6550.76
568_G575_S0.6540.76
496_V502_R0.6520.75
317_T428_K0.6520.75
342_N345_K0.6520.75
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506_G570_Y0.6480.75
215_I218_V0.6470.75
244_I277_Y0.6460.75
536_Y579_A0.6460.75
500_G530_G0.6460.75
503_G568_G0.6460.75
506_G583_A0.6450.75
221_L252_E0.6450.75
272_D275_L0.6440.74
219_C229_Y0.6440.74
506_G580_F0.6430.74
627_G645_V0.6430.74
485_F595_C0.6410.74
529_G573_V0.6400.74
505_F569_S0.6390.74
216_E219_C0.6390.74
222_D240_L0.6380.74
339_Y391_E0.6380.74
225_L235_I0.6380.74
290_T293_D0.6370.74
529_G574_D0.6370.74
533_P537_I0.6350.73
498_Q573_V0.6330.73
342_N349_E0.6320.73
498_Q571_H0.6320.73
151_L159_A0.6320.73
329_V333_T0.6310.73
280_A302_S0.6310.73
310_A376_A0.6300.73
285_A288_K0.6300.73
485_F591_A0.6290.73
101_G279_P0.6280.73
17_A62_T0.6280.73
197_K201_E0.6280.73
163_Q269_L0.6270.72
677_V682_A0.6270.72
498_Q568_G0.6270.72
526_A562_K0.6260.72
92_V119_V0.6260.72
424_I428_K0.6260.72
211_R214_L0.6250.72
98_V128_V0.6250.72
607_E668_T0.6240.72
289_G294_T0.6240.72
525_N531_V0.6220.72
187_E194_S0.6200.72
107_D113_E0.6190.71
484_T560_D0.6180.71
220_E225_L0.6180.71
654_A667_F0.6180.71
40_I264_N0.6180.71
499_S503_G0.6170.71
341_K391_E0.6170.71
338_S390_D0.6170.71
510_I591_A0.6160.71
166_I185_F0.6150.71
529_G533_P0.6150.71
623_T632_M0.6140.71
67_A373_I0.6130.71
167_G171_N0.6130.71
119_V123_A0.6130.71
213_S217_A0.6130.71
7_L282_T0.6130.71
86_V118_T0.6130.71
325_T382_T0.6120.71
179_V244_I0.6120.71
558_L563_A0.6120.71
544_L588_L0.6110.70
500_G529_G0.6110.70
500_G571_H0.6110.70
477_P651_F0.6110.70
238_D241_K0.6110.70
633_E639_Q0.6110.70
155_L159_A0.6110.70
302_S331_S0.6100.70
554_A599_L0.6100.70
175_I269_L0.6100.70
87_D92_V0.6090.70
233_E243_G0.6080.70
409_V472_A0.6060.70
496_V505_F0.6060.70
298_I393_D0.6060.70
317_T323_K0.6060.70
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493_G502_R0.6050.70
309_S395_V0.6050.70
10_T372_D0.6050.70
286_A299_E0.6030.70
14_G96_L0.6030.70
567_D571_H0.6020.69
553_L597_P0.6010.69
14_G17_A0.6000.69
30_I267_V0.6000.69
539_A543_G0.5990.69
503_G571_H0.5990.69
239_E242_A0.5970.69
93_E126_Y0.5970.69
139_K146_Y0.5960.69
212_N232_G0.5960.69
604_M650_M0.5960.69
529_G532_V0.5960.69
504_Q579_A0.5940.68
540_V584_A0.5940.68
571_H575_S0.5930.68
134_V148_V0.5930.68
285_A290_T0.5930.68
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429_L468_F0.5900.68
144_F258_V0.5890.68
189_D192_T0.5890.68
536_Y580_F0.5880.68
132_V159_A0.5880.68
614_Y662_Q0.5870.67
342_N386_D0.5860.67
494_K506_G0.5860.67
486_R597_P0.5860.67
571_H580_F0.5860.67
270_V274_V0.5850.67
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620_G624_S0.5850.67
227_D230_L0.5840.67
96_L102_A0.5840.67
495_F504_Q0.5840.67
568_G573_V0.5830.67
138_D260_S0.5830.67
287_I290_T0.5820.67
320_Y324_L0.5790.66
112_V155_L0.5790.66
631_G639_Q0.5780.66
127_G251_V0.5780.66
547_A585_S0.5770.66
420_D424_I0.5770.66
218_V243_G0.5770.66
44_H50_M0.5760.66
215_I220_E0.5750.66
133_F257_L0.5740.66
609_V668_T0.5740.66
291_R393_D0.5740.66
536_Y576_N0.5720.65
538_P541_Q0.5710.65
181_N204_K0.5710.65
200_P203_Y0.5710.65
54_E466_R0.5700.65
317_T431_E0.5690.65
479_V651_F0.5680.65
177_D180_E0.5680.65
20_D61_I0.5670.65
391_E394_L0.5670.65
220_E229_Y0.5670.65
358_H363_E0.5650.65
298_I302_S0.5650.65
164_L214_L0.5650.65
465_K472_A0.5640.64
298_I301_H0.5640.64
418_D422_M0.5640.64
492_E569_S0.5620.64
498_Q574_D0.5600.64
221_L225_L0.5590.64
489_A512_F0.5590.64
345_K396_I0.5580.64
214_L253_F0.5580.64
31_L68_T0.5580.64
92_V97_R0.5570.63
197_K200_P0.5570.63
236_T243_G0.5570.63
29_R33_Y0.5560.63
484_T561_I0.5560.63
345_K386_D0.5560.63
410_A446_Q0.5560.63
554_A685_I0.5550.63
166_I174_G0.5550.63
442_P549_E0.5550.63
226_M230_L0.5550.63
530_G574_D0.5540.63
312_A388_L0.5540.63
94_R99_L0.5540.63
512_F588_L0.5530.63
36_R363_E0.5530.63
488_G566_F0.5520.63
330_Y397_L0.5520.63
499_S502_R0.5510.63
619_M631_G0.5510.63
452_M456_H0.5500.62
619_M629_V0.5500.62
89_T93_E0.5500.62
108_A175_I0.5500.62
499_S571_H0.5490.62
506_G509_W0.5480.62
552_V591_A0.5480.62
533_P538_P0.5480.62
306_E333_T0.5480.62
502_R531_V0.5480.62
143_D149_G0.5480.62
543_G584_A0.5470.62
261_A267_V0.5470.62
225_L243_G0.5460.62
20_D115_Q0.5450.62
303_S333_T0.5450.62
356_Q372_D0.5450.62
32_F190_L0.5450.62
426_L436_F0.5450.62
513_E522_E0.5440.62
97_R330_Y0.5440.62
10_T78_N0.5430.61
503_G575_S0.5430.61
308_F374_A0.5420.61
110_S113_E0.5420.61
515_N521_F0.5420.61
67_A80_I0.5420.61
521_F544_L0.5420.61
499_S530_G0.5410.61
258_V456_H0.5410.61
523_F568_G0.5400.61
176_I183_A0.5380.61
42_E47_A0.5380.61
91_E314_K0.5370.61
89_T122_Q0.5370.61
115_Q122_Q0.5370.61
134_V139_K0.5360.60
52_W66_A0.5360.60
53_M463_R0.5350.60
619_M641_V0.5350.60
64_T463_R0.5350.60
307_P390_D0.5350.60
493_G587_A0.5350.60
219_C223_E0.5350.60
491_V511_E0.5350.60
501_G571_H0.5350.60
34_T71_Q0.5340.60
513_E524_E0.5340.60
547_A565_L0.5330.60
553_L599_L0.5330.60
232_G235_I0.5330.60
17_A27_T0.5320.60
134_V256_V0.5320.60
115_Q119_V0.5320.60
678_P681_V0.5320.60
676_E682_A0.5320.60
523_F533_P0.5320.60
302_S306_E0.5310.60
109_Q132_V0.5310.60
418_D421_K0.5310.60
219_C232_G0.5310.60
120_W124_T0.5310.60
161_A210_L0.5300.60
355_L362_R0.5290.59
683_E686_I0.5290.59
309_S389_C0.5280.59
228_K232_G0.5280.59
88_F459_I0.5280.59
16_M123_A0.5280.59
512_F584_A0.5280.59
496_V529_G0.5270.59
107_D146_Y0.5260.59
439_Q442_P0.5260.59
105_V261_A0.5260.59
150_T153_D0.5260.59
32_F37_I0.5250.59
144_F147_S0.5250.59
32_F264_N0.5230.59
532_V571_H0.5220.58
458_D465_K0.5220.58
163_Q175_I0.5220.58
186_Y268_Q0.5210.58
626_R674_Y0.5200.58
10_T323_K0.5200.58
499_S532_V0.5190.58
311_L400_M0.5190.58
176_I207_A0.5180.58
544_L547_A0.5180.58
498_Q567_D0.5180.58
77_V274_V0.5170.58
58_E462_D0.5170.58
508_V583_A0.5160.58
336_S353_R0.5150.57
496_V571_H0.5150.57
234_E237_I0.5150.57
44_H47_A0.5150.57
499_S529_G0.5140.57
28_E41_G0.5140.57
131_I273_A0.5140.57
243_G246_K0.5140.57
612_E623_T0.5140.57
524_E529_G0.5140.57
179_V218_V0.5140.57
503_G567_D0.5140.57
16_M147_S0.5130.57
97_R126_Y0.5130.57
429_L436_F0.5130.57
429_L470_V0.5120.57
599_L686_I0.5120.57
19_I61_I0.5120.57
159_A256_V0.5120.57
263_K266_G0.5120.57
650_M667_F0.5110.57
353_R377_V0.5110.57
60_G92_V0.5110.57
221_L246_K0.5100.57
608_V643_A0.5100.57
34_T271_L0.5100.57
44_H60_G0.5100.57
16_M119_V0.5090.57
163_Q177_D0.5090.57
295_N298_I0.5090.57
110_S116_T0.5090.57
152_R217_A0.5080.56
334_L376_A0.5080.56
426_L449_I0.5080.56
676_E679_K0.5070.56
612_E634_A0.5070.56
12_N15_I0.5070.56
536_Y568_G0.5070.56
464_M472_A0.5070.56
529_G568_G0.5060.56
19_I85_H0.5060.56
424_I427_A0.5060.56
291_R295_N0.5050.56
157_A254_Y0.5050.56
490_K594_K0.5050.56
608_V618_I0.5050.56
318_D321_V0.5040.56
355_L365_I0.5040.56
85_H94_R0.5040.56
331_S370_A0.5040.56
164_L175_I0.5040.56
139_K150_T0.5040.56
326_F375_A0.5030.56
259_G263_K0.5030.56
319_P659_S0.5030.56
655_T659_S0.5020.56
292_P295_N0.5020.56
527_I540_V0.5020.56
130_R251_V0.5020.56
407_I652_G0.5010.55
494_K502_R0.5010.55
221_L240_L0.5010.55
502_R585_S0.5010.55
29_R267_V0.5010.55
505_F575_S0.5000.55
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4kiyV 1 0.9754 100 0.2 Contact Map
1darA 1 0.8844 100 0.203 Contact Map
2xexA 1 0.9769 100 0.206 Contact Map
4fn5A 1 0.9451 100 0.23 Contact Map
2dy1A 1 0.9494 100 0.256 Contact Map
4w224 1 0.987 100 0.269 Contact Map
1n0uA 1 0.9465 100 0.274 Contact Map
3j25A 1 0.9061 100 0.299 Contact Map
2yweA 1 0.6575 100 0.507 Contact Map
4zciA 1 0.6532 100 0.511 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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