EFG - BACSU - GREMLIN Contacts

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EFG - Elongation factor G

UniProt:	P80868	Sequences: MAREFSLEKTRNIGIMAHIDAGKTTTTERILFYTGRIHKIGETHEGASQMDWMEQEQERGITITSAATTAQWKGYRVNIIDTPGHVDFTVEVERSLRVLDGAVAVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKIGADFLYSVGTLRDRLQANAHAIQLPIGAEDNFEGIIDLVENVAYFYEDDLGTRSDAKEIPEEYKEQAEELRNSLIEAVCELDEELMDKYLEGEEITIDELKAGIRKGTLNVEFYPVLVGSAFKNKGVQLVLDAVLDYLPAPTDVAAIKGTRPDTNEEIERHSSDEEPFSALAFKVMTDPYVGKLTFFRVYSGTLDSGSYVKNSTKGKRERVGRILQMHANSREEISTVYAGDIAAAVGLKDTTTGDTLCDEKDLVILESMEFPEPVIDVAIEPKSKADQDKMGIALAKLAEEDPTFRTQTNPETGQTIISGMGELHLDIIVDRMKREFKVEANVGAPQVAYRETFRTGAKVEGKFVRQSGGRGQFGHVWIEFEPNEEGAGFEFENAIVGGVVPREYIPAVQAGLEDALENGVLAGFPLIDIKAKLFDGSYHDVDSNEMAFKVAASMALKNAVSKCNPVLLEPIMKVEVVIPEEYMGDIMGDITSRRGRVEGMEARGNAQVVRAMVPLAEMFGYATALRSNTQGRGTFTMHMDHYEEVPKSVAEEIIKKNKGE	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	692 (680)
Sequences:	5391 (2729)
Seq/√Len:	104.7

ECOLI - EFG RF3 LEPA TYPA
BACSU - EFG LEPA TYPA
HALSA - EF2
SULSO - EF2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
368_V	374_A	5.813	1.00
490_K	511_E	4.135	1.00
541_Q	545_E	4.095	1.00
492_E	507_H	3.844	1.00
487_T	596_N	3.684	1.00
513_E	562_K	3.570	1.00
228_K	239_E	3.546	1.00
181_N	207_A	3.483	1.00
133_F	261_A	3.360	1.00
521_F	541_Q	3.356	1.00
109_Q	139_K	3.251	1.00
512_F	563_A	3.231	1.00
257_L	273_A	3.194	1.00
301_H	306_E	3.018	1.00
241_K	276_D	3.000	1.00
486_R	676_E	2.991	1.00
327_F	376_A	2.978	1.00
520_G	560_D	2.972	1.00
610_I	665_G	2.968	1.00
546_D	581_K	2.931	1.00
133_F	259_G	2.923	1.00
335_D	367_T	2.906	1.00
605_K	670_H	2.889	1.00
590_N	594_K	2.881	1.00
107_D	110_S	2.855	1.00
50_M	68_T	2.841	1.00
162_I	257_L	2.787	1.00
312_A	325_T	2.745	1.00
511_E	566_F	2.713	1.00
526_A	564_K	2.711	1.00
513_E	564_K	2.682	1.00
558_L	592_V	2.631	1.00
106_L	116_T	2.619	1.00
27_T	79_I	2.600	1.00
425_A	464_M	2.599	1.00
634_A	639_Q	2.557	1.00
236_T	239_E	2.552	1.00
488_G	513_E	2.538	1.00
182_V	196_A	2.516	1.00
408_D	450_S	2.509	1.00
518_G	560_D	2.509	1.00
436_F	449_I	2.496	1.00
539_A	577_E	2.482	1.00
621_D	653_Y	2.474	1.00
329_V	368_V	2.464	1.00
206_Q	209_E	2.462	1.00
510_I	587_A	2.448	1.00
204_K	208_E	2.443	1.00
201_E	204_K	2.440	1.00
149_G	153_D	2.414	1.00
577_E	581_K	2.378	1.00
524_E	562_K	2.368	1.00
677_V	685_I	2.288	1.00
323_K	431_E	2.278	1.00
180_E	237_I	2.241	1.00
227_D	231_E	2.176	1.00
644_M	673_H	2.164	1.00
414_K	471_E	2.154	1.00
146_Y	150_T	2.143	1.00
490_K	566_F	2.127	1.00
108_A	137_M	2.093	1.00
176_I	203_Y	2.078	1.00
511_E	564_K	2.078	1.00
509_W	566_F	2.071	1.00
288_K	297_E	2.068	1.00
222_D	246_K	2.049	1.00
414_K	473_N	2.042	1.00
522_E	562_K	2.038	1.00
465_K	471_E	2.030	1.00
622_I	627_G	2.024	1.00
206_Q	210_L	2.022	1.00
436_F	460_I	2.013	1.00
677_V	681_V	2.011	1.00
343_S	389_C	2.009	1.00
145_L	206_Q	1.997	1.00
16_M	104_A	1.996	1.00
494_K	505_F	1.978	1.00
507_H	569_S	1.977	1.00
628_R	675_E	1.957	1.00
608_V	622_I	1.957	1.00
132_V	151_L	1.956	1.00
308_F	340_V	1.954	1.00
511_E	526_A	1.953	1.00
187_E	195_D	1.951	1.00
13_I	77_V	1.931	1.00
527_I	531_V	1.926	1.00
517_E	560_D	1.912	1.00
327_F	374_A	1.900	1.00
209_E	213_S	1.883	1.00
43_T	48_S	1.882	1.00
300_R	306_E	1.873	1.00
333_T	367_T	1.859	1.00
516_E	519_A	1.857	1.00
521_F	545_E	1.852	1.00
147_S	150_T	1.844	1.00
404_E	437_R	1.819	1.00
544_L	584_A	1.811	1.00
329_V	374_A	1.807	1.00
160_H	253_F	1.799	1.00
607_E	640_V	1.794	1.00
605_K	642_R	1.779	1.00
548_L	561_I	1.774	1.00
430_A	436_F	1.772	1.00
488_G	511_E	1.756	1.00
303_S	306_E	1.755	1.00
588_L	592_V	1.751	1.00
671_M	674_Y	1.751	1.00
412_E	473_N	1.740	1.00
182_V	198_E	1.735	1.00
291_R	298_I	1.724	1.00
345_K	383_T	1.718	1.00
180_E	196_A	1.703	1.00
298_I	395_V	1.700	1.00
164_L	203_Y	1.694	1.00
184_Y	269_L	1.692	1.00
181_N	208_E	1.689	1.00
235_I	243_G	1.681	1.00
519_A	522_E	1.680	1.00
510_I	544_L	1.674	1.00
576_N	579_A	1.660	1.00
215_I	240_L	1.656	1.00
34_T	70_A	1.651	1.00
679_K	683_E	1.649	1.00
210_L	213_S	1.645	1.00
152_R	213_S	1.643	1.00
521_F	548_L	1.631	1.00
131_I	278_L	1.601	1.00
492_E	509_W	1.591	1.00
335_D	338_S	1.589	1.00
644_M	672_D	1.583	1.00
52_W	64_T	1.578	1.00
633_E	642_R	1.575	1.00
605_K	672_D	1.574	1.00
347_K	381_D	1.570	1.00
224_E	227_D	1.568	1.00
185_F	197_K	1.565	1.00
218_V	247_G	1.563	1.00
486_R	596_N	1.562	1.00
37_I	49_Q	1.559	1.00
544_L	563_A	1.557	1.00
439_Q	450_S	1.557	1.00
16_M	102_A	1.549	1.00
606_V	650_M	1.531	1.00
199_I	207_A	1.530	1.00
379_L	382_T	1.522	1.00
489_A	595_C	1.520	1.00
65_S	80_I	1.520	1.00
356_Q	365_I	1.516	1.00
68_T	358_H	1.510	1.00
341_K	394_L	1.509	1.00
598_V	676_E	1.506	1.00
494_K	507_H	1.504	1.00
145_L	210_L	1.501	1.00
515_N	519_A	1.501	1.00
107_D	147_S	1.472	1.00
408_D	448_I	1.467	1.00
354_I	376_A	1.460	1.00
512_F	591_A	1.456	1.00
490_K	509_W	1.456	1.00
70_A	79_I	1.449	1.00
9_K	75_Y	1.446	1.00
558_L	588_L	1.445	1.00
491_V	590_N	1.441	1.00
336_S	366_S	1.439	1.00
119_V	122_Q	1.435	1.00
590_N	593_S	1.434	1.00
242_A	246_K	1.427	1.00
630_E	644_M	1.423	1.00
344_T	386_D	1.422	1.00
228_K	236_T	1.418	1.00
223_E	227_D	1.410	1.00
292_P	296_E	1.403	1.00
228_K	233_E	1.401	1.00
12_N	78_N	1.401	1.00
481_Y	648_A	1.401	1.00
486_R	598_V	1.398	1.00
183_A	200_P	1.397	1.00
334_L	351_V	1.392	1.00
50_M	66_A	1.387	1.00
493_G	506_G	1.387	1.00
310_A	327_F	1.384	1.00
108_A	134_V	1.382	1.00
223_E	252_E	1.379	1.00
309_S	397_L	1.377	1.00
524_E	564_K	1.377	1.00
341_K	346_G	1.377	1.00
117_E	664_R	1.376	1.00
166_I	176_I	1.375	1.00
14_G	99_L	1.372	1.00
291_R	294_T	1.370	1.00
461_V	474_V	1.370	1.00
148_V	161_A	1.368	1.00
612_E	639_Q	1.367	1.00
493_G	586_M	1.366	1.00
632_M	639_Q	1.364	1.00
15_I	27_T	1.361	1.00
90_V	435_T	1.360	1.00
187_E	193_R	1.360	1.00
548_L	588_L	1.355	0.99
409_V	474_V	1.348	0.99
106_L	151_L	1.348	0.99
178_L	181_N	1.348	0.99
540_V	565_L	1.345	0.99
75_Y	275_L	1.341	0.99
415_S	418_D	1.340	0.99
198_E	201_E	1.339	0.99
618_I	661_T	1.338	0.99
145_L	164_L	1.336	0.99
181_N	199_I	1.328	0.99
312_A	382_T	1.327	0.99
635_R	638_A	1.323	0.99
37_I	40_I	1.316	0.99
124_T	130_R	1.314	0.99
241_K	277_Y	1.313	0.99
365_I	368_V	1.311	0.99
300_R	395_V	1.310	0.99
218_V	221_L	1.309	0.99
333_T	369_Y	1.304	0.99
515_N	522_E	1.303	0.99
443_E	482_R	1.301	0.99
532_V	565_L	1.292	0.99
462_D	466_R	1.287	0.99
214_L	218_V	1.281	0.99
353_R	364_E	1.279	0.99
682_A	686_I	1.277	0.99
9_K	74_G	1.270	0.99
289_G	292_P	1.268	0.99
26_T	261_A	1.259	0.99
525_N	534_R	1.253	0.99
164_L	207_A	1.252	0.99
517_E	520_G	1.249	0.99
116_T	132_V	1.248	0.99
106_L	132_V	1.244	0.99
173_E	185_F	1.244	0.99
107_D	150_T	1.242	0.99
449_I	460_I	1.236	0.99
290_T	294_T	1.231	0.99
607_E	642_R	1.229	0.99
26_T	105_V	1.225	0.99
164_L	210_L	1.224	0.99
493_G	496_V	1.222	0.99
246_K	250_N	1.221	0.99
11_R	281_P	1.217	0.99
430_A	449_I	1.212	0.99
523_F	565_L	1.208	0.99
635_R	640_V	1.208	0.99
208_E	212_N	1.206	0.99
561_I	588_L	1.205	0.99
605_K	644_M	1.202	0.99
422_M	464_M	1.201	0.99
454_E	652_G	1.199	0.99
218_V	225_L	1.198	0.99
615_M	641_V	1.198	0.99
661_T	665_G	1.193	0.99
104_A	132_V	1.190	0.99
107_D	139_K	1.190	0.99
599_L	685_I	1.189	0.99
656_A	660_N	1.188	0.99
485_F	597_P	1.188	0.99
211_R	215_I	1.187	0.99
533_P	570_Y	1.186	0.99
162_I	273_A	1.176	0.99
27_T	50_M	1.173	0.99
340_V	351_V	1.172	0.99
188_D	192_T	1.170	0.99
148_V	256_V	1.169	0.98
151_L	256_V	1.155	0.98
441_N	444_T	1.155	0.98
184_Y	196_A	1.148	0.98
48_S	57_Q	1.145	0.98
390_D	393_D	1.140	0.98
515_N	560_D	1.134	0.98
52_W	316_M	1.133	0.98
101_G	278_L	1.131	0.98
166_I	183_A	1.131	0.98
619_M	623_T	1.129	0.98
72_W	272_D	1.128	0.98
26_T	270_V	1.127	0.98
349_E	382_T	1.123	0.98
622_I	645_V	1.122	0.98
323_K	435_T	1.119	0.98
650_M	669_M	1.118	0.98
166_I	203_Y	1.117	0.98
316_M	326_F	1.114	0.98
508_V	532_V	1.112	0.98
491_V	594_K	1.112	0.98
585_S	589_K	1.111	0.98
149_G	152_R	1.094	0.98
180_E	241_K	1.094	0.98
368_V	376_A	1.093	0.98
308_F	334_L	1.092	0.98
286_A	289_G	1.091	0.98
17_A	21_A	1.087	0.98
525_N	528_V	1.084	0.98
71_Q	76_R	1.080	0.97
280_A	283_D	1.075	0.97
110_S	150_T	1.066	0.97
218_V	240_L	1.065	0.97
58_E	466_R	1.064	0.97
274_V	278_L	1.064	0.97
93_E	125_T	1.061	0.97
145_L	149_G	1.060	0.97
604_M	647_L	1.056	0.97
355_L	364_E	1.056	0.97
526_A	566_F	1.053	0.97
485_F	592_V	1.051	0.97
498_Q	503_G	1.051	0.97
219_C	243_G	1.049	0.97
582_V	585_S	1.049	0.97
327_F	334_L	1.049	0.97
235_I	240_L	1.047	0.97
491_V	591_A	1.047	0.97
33_Y	268_Q	1.046	0.97
16_M	96_L	1.046	0.97
179_V	277_Y	1.045	0.97
308_F	329_V	1.042	0.97
334_L	340_V	1.042	0.97
657_L	661_T	1.039	0.97
553_L	686_I	1.038	0.97
626_R	649_E	1.036	0.97
235_I	239_E	1.033	0.97
55_Q	462_D	1.029	0.97
606_V	643_A	1.026	0.97
123_A	130_R	1.025	0.97
150_T	154_R	1.023	0.96
495_F	586_M	1.023	0.96
160_H	214_L	1.015	0.96
50_M	62_T	1.014	0.96
309_S	331_S	1.014	0.96
463_R	467_E	1.012	0.96
327_F	368_V	1.011	0.96
10_T	76_R	1.007	0.96
618_I	657_L	0.999	0.96
76_R	356_Q	0.999	0.96
610_I	618_I	0.998	0.96
515_N	562_K	0.997	0.96
237_I	241_K	0.995	0.96
285_A	289_G	0.990	0.96
502_R	576_N	0.990	0.96
137_M	168_A	0.989	0.96
525_N	537_I	0.987	0.96
645_V	653_Y	0.986	0.96
245_R	249_L	0.985	0.96
575_S	580_F	0.985	0.96
288_K	299_E	0.984	0.96
245_R	283_D	0.981	0.96
125_T	401_E	0.980	0.96
493_G	509_W	0.976	0.95
304_D	333_T	0.973	0.95
178_L	211_R	0.972	0.95
412_E	475_G	0.971	0.95
506_G	569_S	0.971	0.95
104_A	116_T	0.970	0.95
342_N	382_T	0.970	0.95
412_E	446_Q	0.970	0.95
604_M	669_M	0.968	0.95
512_F	544_L	0.968	0.95
601_E	626_R	0.966	0.95
73_K	276_D	0.964	0.95
205_E	208_E	0.963	0.95
609_V	640_V	0.961	0.95
93_E	122_Q	0.959	0.95
599_L	682_A	0.958	0.95
527_I	530_G	0.955	0.95
134_V	147_S	0.953	0.95
617_D	632_M	0.953	0.95
519_A	560_D	0.950	0.95
135_N	261_A	0.946	0.95
446_Q	475_G	0.944	0.95
509_W	567_D	0.943	0.94
186_Y	194_S	0.939	0.94
219_C	235_I	0.936	0.94
205_E	209_E	0.936	0.94
503_G	574_D	0.934	0.94
104_A	119_V	0.933	0.94
355_L	377_V	0.931	0.94
30_I	70_A	0.930	0.94
76_R	372_D	0.927	0.94
508_V	584_A	0.926	0.94
615_M	632_M	0.926	0.94
588_L	597_P	0.925	0.94
132_V	254_Y	0.925	0.94
59_R	462_D	0.922	0.94
545_E	549_E	0.919	0.94
568_G	571_H	0.919	0.94
621_D	660_N	0.916	0.94
628_R	644_M	0.913	0.93
25_T	43_T	0.912	0.93
144_F	161_A	0.910	0.93
100_D	328_R	0.906	0.93
365_I	374_A	0.905	0.93
179_V	237_I	0.904	0.93
191_G	268_Q	0.904	0.93
531_V	567_D	0.903	0.93
324_L	375_A	0.901	0.93
158_N	217_A	0.901	0.93
52_W	360_N	0.900	0.93
539_A	581_K	0.900	0.93
112_V	116_T	0.900	0.93
578_M	582_V	0.899	0.93
608_V	645_V	0.898	0.93
510_I	565_L	0.894	0.93
71_Q	74_G	0.894	0.93
429_L	464_M	0.892	0.93
304_D	369_Y	0.892	0.93
80_I	99_L	0.891	0.93
510_I	563_A	0.890	0.93
313_F	373_I	0.890	0.93
238_D	242_A	0.887	0.92
326_F	357_M	0.887	0.92
351_V	376_A	0.885	0.92
184_Y	194_S	0.882	0.92
244_I	253_F	0.882	0.92
54_E	57_Q	0.880	0.92
247_G	253_F	0.879	0.92
73_K	275_L	0.879	0.92
137_M	142_A	0.877	0.92
53_M	64_T	0.873	0.92
203_Y	207_A	0.873	0.92
609_V	635_R	0.872	0.92
42_E	45_E	0.872	0.92
495_F	502_R	0.869	0.92
446_Q	477_P	0.865	0.92
537_I	565_L	0.865	0.92
494_K	569_S	0.864	0.91
162_I	244_I	0.864	0.91
164_L	206_Q	0.862	0.91
315_V	325_T	0.861	0.91
90_V	402_F	0.861	0.91
73_K	272_D	0.861	0.91
103_V	270_V	0.860	0.91
179_V	240_L	0.859	0.91
156_Q	637_N	0.858	0.91
516_E	520_G	0.857	0.91
558_L	561_I	0.855	0.91
178_L	207_A	0.853	0.91
512_F	592_V	0.851	0.91
493_G	497_R	0.850	0.91
515_N	520_G	0.850	0.91
260_S	263_K	0.848	0.91
221_L	247_G	0.848	0.91
546_D	577_E	0.847	0.91
103_V	274_V	0.846	0.91
547_A	588_L	0.844	0.90
621_D	625_R	0.843	0.90
622_I	641_V	0.843	0.90
493_G	507_H	0.841	0.90
356_Q	363_E	0.840	0.90
44_H	48_S	0.839	0.90
13_I	274_V	0.839	0.90
335_D	366_S	0.838	0.90
461_V	465_K	0.838	0.90
368_V	372_D	0.834	0.90
508_V	587_A	0.832	0.90
532_V	537_I	0.828	0.90
621_D	656_A	0.827	0.90
137_M	172_F	0.826	0.90
221_L	243_G	0.826	0.90
593_S	597_P	0.825	0.89
37_I	43_T	0.825	0.89
489_A	591_A	0.824	0.89
438_T	447_T	0.824	0.89
31_L	49_Q	0.824	0.89
348_R	391_E	0.823	0.89
17_A	20_D	0.822	0.89
132_V	256_V	0.821	0.89
223_E	226_M	0.821	0.89
306_E	331_S	0.819	0.89
571_H	574_D	0.818	0.89
224_E	228_K	0.815	0.89
98_V	313_F	0.814	0.89
407_I	651_F	0.813	0.89
203_Y	206_Q	0.813	0.89
493_G	590_N	0.812	0.89
356_Q	368_V	0.812	0.89
70_A	77_V	0.809	0.89
503_G	529_G	0.808	0.88
340_V	388_L	0.806	0.88
160_H	244_I	0.804	0.88
343_S	396_I	0.795	0.88
527_I	537_I	0.794	0.88
63_I	459_I	0.794	0.88
201_E	205_E	0.790	0.87
647_L	669_M	0.790	0.87
220_E	226_M	0.787	0.87
516_E	560_D	0.786	0.87
120_W	130_R	0.784	0.87
480_A	674_Y	0.783	0.87
624_S	656_A	0.783	0.87
543_G	547_A	0.783	0.87
498_Q	529_G	0.781	0.87
173_E	202_E	0.779	0.87
568_G	574_D	0.777	0.86
172_F	175_I	0.776	0.86
329_V	369_Y	0.776	0.86
30_I	34_T	0.775	0.86
578_M	581_K	0.775	0.86
82_T	92_V	0.774	0.86
583_A	587_A	0.773	0.86
515_N	518_G	0.772	0.86
357_M	375_A	0.772	0.86
300_R	309_S	0.771	0.86
487_T	514_P	0.770	0.86
289_G	300_R	0.769	0.86
284_V	302_S	0.769	0.86
100_D	129_P	0.768	0.86
41_G	46_G	0.767	0.86
497_R	501_G	0.765	0.86
28_E	48_S	0.764	0.86
215_I	229_Y	0.764	0.86
496_V	503_G	0.760	0.85
57_Q	360_N	0.759	0.85
160_H	217_A	0.758	0.85
152_R	159_A	0.757	0.85
609_V	666_T	0.757	0.85
546_D	585_S	0.756	0.85
379_L	388_L	0.756	0.85
284_V	287_I	0.755	0.85
425_A	429_L	0.753	0.85
105_V	135_N	0.753	0.85
538_P	542_A	0.753	0.85
528_V	534_R	0.752	0.85
504_Q	576_N	0.752	0.85
163_Q	257_L	0.750	0.85
54_E	58_E	0.749	0.84
48_S	68_T	0.749	0.84
525_N	541_Q	0.748	0.84
528_V	531_V	0.748	0.84
163_Q	258_V	0.747	0.84
224_E	239_E	0.744	0.84
216_E	220_E	0.744	0.84
27_T	68_T	0.743	0.84
228_K	235_I	0.742	0.84
33_Y	264_N	0.742	0.84
51_D	56_E	0.741	0.84
430_A	438_T	0.740	0.84
167_G	172_F	0.738	0.84
181_N	211_R	0.738	0.84
145_L	203_Y	0.737	0.83
15_I	103_V	0.736	0.83
496_V	507_H	0.736	0.83
93_E	119_V	0.735	0.83
152_R	158_N	0.735	0.83
310_A	388_L	0.733	0.83
680_S	683_E	0.733	0.83
503_G	573_V	0.731	0.83
611_P	664_R	0.730	0.83
439_Q	448_I	0.729	0.83
552_V	558_L	0.729	0.83
290_T	295_N	0.729	0.83
44_H	262_F	0.728	0.83
41_G	45_E	0.728	0.83
554_A	686_I	0.727	0.83
251_V	254_Y	0.726	0.83
592_V	597_P	0.726	0.83
143_D	146_Y	0.726	0.83
606_V	669_M	0.725	0.82
185_F	195_D	0.724	0.82
525_N	532_V	0.723	0.82
454_E	655_T	0.719	0.82
529_G	567_D	0.718	0.82
508_V	565_L	0.718	0.82
132_V	147_S	0.717	0.82
498_Q	501_G	0.717	0.82
291_R	296_E	0.717	0.82
50_M	358_H	0.717	0.82
518_G	521_F	0.716	0.82
429_L	460_I	0.715	0.82
36_R	358_H	0.713	0.81
508_V	540_V	0.712	0.81
273_A	277_Y	0.712	0.81
315_V	384_T	0.711	0.81
33_Y	191_G	0.711	0.81
512_F	561_I	0.710	0.81
167_G	173_E	0.708	0.81
645_V	650_M	0.707	0.81
285_A	302_S	0.707	0.81
633_E	640_V	0.706	0.81
16_M	400_M	0.706	0.81
102_A	128_V	0.706	0.81
484_T	600_L	0.706	0.81
423_G	447_T	0.705	0.81
581_K	585_S	0.704	0.81
503_G	530_G	0.703	0.80
540_V	543_G	0.701	0.80
25_T	40_I	0.701	0.80
644_M	675_E	0.701	0.80
41_G	47_A	0.700	0.80
532_V	540_V	0.699	0.80
527_I	532_V	0.699	0.80
339_Y	348_R	0.698	0.80
303_S	307_P	0.697	0.80
183_A	197_K	0.697	0.80
492_E	496_V	0.696	0.80
240_L	247_G	0.695	0.80
652_G	656_A	0.694	0.80
582_V	586_M	0.693	0.80
178_L	214_L	0.693	0.80
532_V	568_G	0.693	0.80
369_Y	372_D	0.692	0.79
552_V	592_V	0.691	0.79
26_T	267_V	0.690	0.79
217_A	220_E	0.690	0.79
107_D	136_K	0.689	0.79
460_I	464_M	0.689	0.79
69_T	76_R	0.689	0.79
318_D	362_R	0.688	0.79
336_S	364_E	0.688	0.79
97_R	122_Q	0.686	0.79
110_S	147_S	0.686	0.79
65_S	95_S	0.685	0.79
167_G	174_G	0.683	0.79
529_G	571_H	0.682	0.78
547_A	558_L	0.681	0.78
55_Q	59_R	0.681	0.78
492_E	590_N	0.681	0.78
36_R	68_T	0.681	0.78
521_F	561_I	0.680	0.78
97_R	311_L	0.680	0.78
300_R	393_D	0.679	0.78
349_E	380_K	0.679	0.78
530_G	533_P	0.679	0.78
293_D	296_E	0.678	0.78
300_R	331_S	0.676	0.78
188_D	193_R	0.675	0.78
451_G	457_L	0.675	0.78
496_V	499_S	0.674	0.78
491_V	595_C	0.674	0.78
493_G	508_V	0.673	0.78
539_A	542_A	0.673	0.78
78_N	372_D	0.673	0.78
109_Q	262_F	0.673	0.78
42_E	48_S	0.672	0.77
354_I	365_I	0.672	0.77
498_Q	530_G	0.671	0.77
146_Y	149_G	0.671	0.77
90_V	399_S	0.670	0.77
682_A	685_I	0.669	0.77
7_L	10_T	0.668	0.77
320_Y	323_K	0.667	0.77
500_G	503_G	0.667	0.77
574_D	580_F	0.667	0.77
615_M	619_M	0.665	0.77
97_R	400_M	0.664	0.77
321_V	355_L	0.664	0.77
308_F	333_T	0.664	0.77
178_L	210_L	0.662	0.76
310_A	334_L	0.662	0.76
563_A	588_L	0.661	0.76
52_W	359_A	0.661	0.76
433_D	456_H	0.661	0.76
501_G	504_Q	0.660	0.76
542_A	545_E	0.660	0.76
615_M	639_Q	0.658	0.76
515_N	524_E	0.658	0.76
612_E	637_N	0.657	0.76
216_E	229_Y	0.657	0.76
568_G	580_F	0.657	0.76
113_E	609_V	0.657	0.76
459_I	462_D	0.657	0.76
652_G	655_T	0.656	0.76
109_Q	146_Y	0.655	0.76
259_G	270_V	0.655	0.76
584_A	588_L	0.655	0.76
568_G	575_S	0.654	0.76
496_V	502_R	0.652	0.75
317_T	428_K	0.652	0.75
342_N	345_K	0.652	0.75
186_Y	269_L	0.652	0.75
253_F	257_L	0.652	0.75
587_A	591_A	0.651	0.75
560_D	563_A	0.651	0.75
499_S	573_V	0.650	0.75
110_S	139_K	0.650	0.75
626_R	678_P	0.650	0.75
625_R	656_A	0.649	0.75
292_P	394_L	0.649	0.75
506_G	570_Y	0.648	0.75
215_I	218_V	0.647	0.75
244_I	277_Y	0.646	0.75
536_Y	579_A	0.646	0.75
500_G	530_G	0.646	0.75
503_G	568_G	0.646	0.75
506_G	583_A	0.645	0.75
221_L	252_E	0.645	0.75
272_D	275_L	0.644	0.74
219_C	229_Y	0.644	0.74
506_G	580_F	0.643	0.74
627_G	645_V	0.643	0.74
485_F	595_C	0.641	0.74
529_G	573_V	0.640	0.74
505_F	569_S	0.639	0.74
216_E	219_C	0.639	0.74
222_D	240_L	0.638	0.74
339_Y	391_E	0.638	0.74
225_L	235_I	0.638	0.74
290_T	293_D	0.637	0.74
529_G	574_D	0.637	0.74
533_P	537_I	0.635	0.73
498_Q	573_V	0.633	0.73
342_N	349_E	0.632	0.73
498_Q	571_H	0.632	0.73
151_L	159_A	0.632	0.73
329_V	333_T	0.631	0.73
280_A	302_S	0.631	0.73
310_A	376_A	0.630	0.73
285_A	288_K	0.630	0.73
485_F	591_A	0.629	0.73
101_G	279_P	0.628	0.73
17_A	62_T	0.628	0.73
197_K	201_E	0.628	0.73
163_Q	269_L	0.627	0.72
677_V	682_A	0.627	0.72
498_Q	568_G	0.627	0.72
526_A	562_K	0.626	0.72
92_V	119_V	0.626	0.72
424_I	428_K	0.626	0.72
211_R	214_L	0.625	0.72
98_V	128_V	0.625	0.72
607_E	668_T	0.624	0.72
289_G	294_T	0.624	0.72
525_N	531_V	0.622	0.72
187_E	194_S	0.620	0.72
107_D	113_E	0.619	0.71
484_T	560_D	0.618	0.71
220_E	225_L	0.618	0.71
654_A	667_F	0.618	0.71
40_I	264_N	0.618	0.71
499_S	503_G	0.617	0.71
341_K	391_E	0.617	0.71
338_S	390_D	0.617	0.71
510_I	591_A	0.616	0.71
166_I	185_F	0.615	0.71
529_G	533_P	0.615	0.71
623_T	632_M	0.614	0.71
67_A	373_I	0.613	0.71
167_G	171_N	0.613	0.71
119_V	123_A	0.613	0.71
213_S	217_A	0.613	0.71
7_L	282_T	0.613	0.71
86_V	118_T	0.613	0.71
325_T	382_T	0.612	0.71
179_V	244_I	0.612	0.71
558_L	563_A	0.612	0.71
544_L	588_L	0.611	0.70
500_G	529_G	0.611	0.70
500_G	571_H	0.611	0.70
477_P	651_F	0.611	0.70
238_D	241_K	0.611	0.70
633_E	639_Q	0.611	0.70
155_L	159_A	0.611	0.70
302_S	331_S	0.610	0.70
554_A	599_L	0.610	0.70
175_I	269_L	0.610	0.70
87_D	92_V	0.609	0.70
233_E	243_G	0.608	0.70
409_V	472_A	0.606	0.70
496_V	505_F	0.606	0.70
298_I	393_D	0.606	0.70
317_T	323_K	0.606	0.70
409_V	461_V	0.605	0.70
493_G	502_R	0.605	0.70
309_S	395_V	0.605	0.70
10_T	372_D	0.605	0.70
286_A	299_E	0.603	0.70
14_G	96_L	0.603	0.70
567_D	571_H	0.602	0.69
553_L	597_P	0.601	0.69
14_G	17_A	0.600	0.69
30_I	267_V	0.600	0.69
539_A	543_G	0.599	0.69
503_G	571_H	0.599	0.69
239_E	242_A	0.597	0.69
93_E	126_Y	0.597	0.69
139_K	146_Y	0.596	0.69
212_N	232_G	0.596	0.69
604_M	650_M	0.596	0.69
529_G	532_V	0.596	0.69
504_Q	579_A	0.594	0.68
540_V	584_A	0.594	0.68
571_H	575_S	0.593	0.68
134_V	148_V	0.593	0.68
285_A	290_T	0.593	0.68
542_A	581_K	0.593	0.68
215_I	219_C	0.593	0.68
527_I	565_L	0.592	0.68
61_I	85_H	0.592	0.68
425_A	470_V	0.592	0.68
429_L	468_F	0.590	0.68
144_F	258_V	0.589	0.68
189_D	192_T	0.589	0.68
536_Y	580_F	0.588	0.68
132_V	159_A	0.588	0.68
614_Y	662_Q	0.587	0.67
342_N	386_D	0.586	0.67
494_K	506_G	0.586	0.67
486_R	597_P	0.586	0.67
571_H	580_F	0.586	0.67
270_V	274_V	0.585	0.67
308_F	327_F	0.585	0.67
620_G	624_S	0.585	0.67
227_D	230_L	0.584	0.67
96_L	102_A	0.584	0.67
495_F	504_Q	0.584	0.67
568_G	573_V	0.583	0.67
138_D	260_S	0.583	0.67
287_I	290_T	0.582	0.67
320_Y	324_L	0.579	0.66
112_V	155_L	0.579	0.66
631_G	639_Q	0.578	0.66
127_G	251_V	0.578	0.66
547_A	585_S	0.577	0.66
420_D	424_I	0.577	0.66
218_V	243_G	0.577	0.66
44_H	50_M	0.576	0.66
215_I	220_E	0.575	0.66
133_F	257_L	0.574	0.66
609_V	668_T	0.574	0.66
291_R	393_D	0.574	0.66
536_Y	576_N	0.572	0.65
538_P	541_Q	0.571	0.65
181_N	204_K	0.571	0.65
200_P	203_Y	0.571	0.65
54_E	466_R	0.570	0.65
317_T	431_E	0.569	0.65
479_V	651_F	0.568	0.65
177_D	180_E	0.568	0.65
20_D	61_I	0.567	0.65
391_E	394_L	0.567	0.65
220_E	229_Y	0.567	0.65
358_H	363_E	0.565	0.65
298_I	302_S	0.565	0.65
164_L	214_L	0.565	0.65
465_K	472_A	0.564	0.64
298_I	301_H	0.564	0.64
418_D	422_M	0.564	0.64
492_E	569_S	0.562	0.64
498_Q	574_D	0.560	0.64
221_L	225_L	0.559	0.64
489_A	512_F	0.559	0.64
345_K	396_I	0.558	0.64
214_L	253_F	0.558	0.64
31_L	68_T	0.558	0.64
92_V	97_R	0.557	0.63
197_K	200_P	0.557	0.63
236_T	243_G	0.557	0.63
29_R	33_Y	0.556	0.63
484_T	561_I	0.556	0.63
345_K	386_D	0.556	0.63
410_A	446_Q	0.556	0.63
554_A	685_I	0.555	0.63
166_I	174_G	0.555	0.63
442_P	549_E	0.555	0.63
226_M	230_L	0.555	0.63
530_G	574_D	0.554	0.63
312_A	388_L	0.554	0.63
94_R	99_L	0.554	0.63
512_F	588_L	0.553	0.63
36_R	363_E	0.553	0.63
488_G	566_F	0.552	0.63
330_Y	397_L	0.552	0.63
499_S	502_R	0.551	0.63
619_M	631_G	0.551	0.63
452_M	456_H	0.550	0.62
619_M	629_V	0.550	0.62
89_T	93_E	0.550	0.62
108_A	175_I	0.550	0.62
499_S	571_H	0.549	0.62
506_G	509_W	0.548	0.62
552_V	591_A	0.548	0.62
533_P	538_P	0.548	0.62
306_E	333_T	0.548	0.62
502_R	531_V	0.548	0.62
143_D	149_G	0.548	0.62
543_G	584_A	0.547	0.62
261_A	267_V	0.547	0.62
225_L	243_G	0.546	0.62
20_D	115_Q	0.545	0.62
303_S	333_T	0.545	0.62
356_Q	372_D	0.545	0.62
32_F	190_L	0.545	0.62
426_L	436_F	0.545	0.62
513_E	522_E	0.544	0.62
97_R	330_Y	0.544	0.62
10_T	78_N	0.543	0.61
503_G	575_S	0.543	0.61
308_F	374_A	0.542	0.61
110_S	113_E	0.542	0.61
515_N	521_F	0.542	0.61
67_A	80_I	0.542	0.61
521_F	544_L	0.542	0.61
499_S	530_G	0.541	0.61
258_V	456_H	0.541	0.61
523_F	568_G	0.540	0.61
176_I	183_A	0.538	0.61
42_E	47_A	0.538	0.61
91_E	314_K	0.537	0.61
89_T	122_Q	0.537	0.61
115_Q	122_Q	0.537	0.61
134_V	139_K	0.536	0.60
52_W	66_A	0.536	0.60
53_M	463_R	0.535	0.60
619_M	641_V	0.535	0.60
64_T	463_R	0.535	0.60
307_P	390_D	0.535	0.60
493_G	587_A	0.535	0.60
219_C	223_E	0.535	0.60
491_V	511_E	0.535	0.60
501_G	571_H	0.535	0.60
34_T	71_Q	0.534	0.60
513_E	524_E	0.534	0.60
547_A	565_L	0.533	0.60
553_L	599_L	0.533	0.60
232_G	235_I	0.533	0.60
17_A	27_T	0.532	0.60
134_V	256_V	0.532	0.60
115_Q	119_V	0.532	0.60
678_P	681_V	0.532	0.60
676_E	682_A	0.532	0.60
523_F	533_P	0.532	0.60
302_S	306_E	0.531	0.60
109_Q	132_V	0.531	0.60
418_D	421_K	0.531	0.60
219_C	232_G	0.531	0.60
120_W	124_T	0.531	0.60
161_A	210_L	0.530	0.60
355_L	362_R	0.529	0.59
683_E	686_I	0.529	0.59
309_S	389_C	0.528	0.59
228_K	232_G	0.528	0.59
88_F	459_I	0.528	0.59
16_M	123_A	0.528	0.59
512_F	584_A	0.528	0.59
496_V	529_G	0.527	0.59
107_D	146_Y	0.526	0.59
439_Q	442_P	0.526	0.59
105_V	261_A	0.526	0.59
150_T	153_D	0.526	0.59
32_F	37_I	0.525	0.59
144_F	147_S	0.525	0.59
32_F	264_N	0.523	0.59
532_V	571_H	0.522	0.58
458_D	465_K	0.522	0.58
163_Q	175_I	0.522	0.58
186_Y	268_Q	0.521	0.58
626_R	674_Y	0.520	0.58
10_T	323_K	0.520	0.58
499_S	532_V	0.519	0.58
311_L	400_M	0.519	0.58
176_I	207_A	0.518	0.58
544_L	547_A	0.518	0.58
498_Q	567_D	0.518	0.58
77_V	274_V	0.517	0.58
58_E	462_D	0.517	0.58
508_V	583_A	0.516	0.58
336_S	353_R	0.515	0.57
496_V	571_H	0.515	0.57
234_E	237_I	0.515	0.57
44_H	47_A	0.515	0.57
499_S	529_G	0.514	0.57
28_E	41_G	0.514	0.57
131_I	273_A	0.514	0.57
243_G	246_K	0.514	0.57
612_E	623_T	0.514	0.57
524_E	529_G	0.514	0.57
179_V	218_V	0.514	0.57
503_G	567_D	0.514	0.57
16_M	147_S	0.513	0.57
97_R	126_Y	0.513	0.57
429_L	436_F	0.513	0.57
429_L	470_V	0.512	0.57
599_L	686_I	0.512	0.57
19_I	61_I	0.512	0.57
159_A	256_V	0.512	0.57
263_K	266_G	0.512	0.57
650_M	667_F	0.511	0.57
353_R	377_V	0.511	0.57
60_G	92_V	0.511	0.57
221_L	246_K	0.510	0.57
608_V	643_A	0.510	0.57
34_T	271_L	0.510	0.57
44_H	60_G	0.510	0.57
16_M	119_V	0.509	0.57
163_Q	177_D	0.509	0.57
295_N	298_I	0.509	0.57
110_S	116_T	0.509	0.57
152_R	217_A	0.508	0.56
334_L	376_A	0.508	0.56
426_L	449_I	0.508	0.56
676_E	679_K	0.507	0.56
612_E	634_A	0.507	0.56
12_N	15_I	0.507	0.56
536_Y	568_G	0.507	0.56
464_M	472_A	0.507	0.56
529_G	568_G	0.506	0.56
19_I	85_H	0.506	0.56
424_I	427_A	0.506	0.56
291_R	295_N	0.505	0.56
157_A	254_Y	0.505	0.56
490_K	594_K	0.505	0.56
608_V	618_I	0.505	0.56
318_D	321_V	0.504	0.56
355_L	365_I	0.504	0.56
85_H	94_R	0.504	0.56
331_S	370_A	0.504	0.56
164_L	175_I	0.504	0.56
139_K	150_T	0.504	0.56
326_F	375_A	0.503	0.56
259_G	263_K	0.503	0.56
319_P	659_S	0.503	0.56
655_T	659_S	0.502	0.56
292_P	295_N	0.502	0.56
527_I	540_V	0.502	0.56
130_R	251_V	0.502	0.56
407_I	652_G	0.501	0.55
494_K	502_R	0.501	0.55
221_L	240_L	0.501	0.55
502_R	585_S	0.501	0.55
29_R	267_V	0.501	0.55
505_F	575_S	0.500	0.55

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4kiyV	1	0.9754	100	0.2	Contact Map
1darA	1	0.8844	100	0.203	Contact Map
2xexA	1	0.9769	100	0.206	Contact Map
4fn5A	1	0.9451	100	0.23	Contact Map
2dy1A	1	0.9494	100	0.256	Contact Map
4w224	1	0.987	100	0.269	Contact Map
1n0uA	1	0.9465	100	0.274	Contact Map
3j25A	1	0.9061	100	0.299	Contact Map
2yweA	1	0.6575	100	0.507	Contact Map
4zciA	1	0.6532	100	0.511	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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