GREMLIN Database
YJLD - NADH dehydrogenase-like protein YjlD
UniProt: P80861 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 392 (317)
Sequences: 35085 (24678)
Seq/√Len: 1386.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
158_L249_A4.0731.00
37_K79_E4.0631.00
4_H31_R3.4131.00
156_T192_K3.0881.00
194_K226_L2.8631.00
89_E97_T2.8231.00
88_K289_D2.8151.00
215_T219_E2.5821.00
192_K224_E2.5761.00
279_N283_Q2.5651.00
33_T76_K2.5641.00
17_S104_V2.5471.00
235_E240_D2.4661.00
238_V246_K2.3791.00
112_A259_Q2.3171.00
270_E277_T2.3041.00
85_V287_H2.2841.00
233_N240_D2.2821.00
198_A230_P2.2341.00
4_H101_D2.2341.00
4_H33_T2.1791.00
102_A289_D2.1531.00
35_V98_L2.1481.00
240_D246_K2.1121.00
5_I21_V2.1031.00
84_S87_K2.1001.00
91_A97_T2.0881.00
158_L196_V2.0821.00
100_Y103_L2.0791.00
3_K33_T2.0741.00
156_T194_K2.0261.00
194_K224_E1.9971.00
6_V35_V1.9851.00
31_R74_D1.9651.00
156_T250_N1.9511.00
110_V261_N1.9451.00
117_P233_N1.9131.00
200_P228_G1.9111.00
272_N275_R1.8991.00
13_G293_A1.7871.00
110_V259_Q1.7691.00
270_E286_S1.7511.00
104_V325_L1.7411.00
235_E238_V1.7341.00
350_R355_A1.7271.00
107_L296_S1.7171.00
272_N298_V1.7031.00
102_A291_F1.7021.00
238_V248_V1.6971.00
230_P242_K1.6951.00
6_V98_L1.6881.00
291_F324_N1.6841.00
232_T242_K1.6661.00
229_L243_D1.6641.00
208_D353_A1.6571.00
263_L266_E1.6301.00
82_S91_A1.6301.00
60_V63_P1.6031.00
89_E99_T1.6011.00
85_V290_V1.5511.00
6_V90_V1.5251.00
128_S131_D1.5141.00
201_K211_I1.5091.00
153_A191_I1.5091.00
196_V247_V1.5051.00
6_V100_Y1.4981.00
130_A133_N1.4841.00
283_Q288_E1.4741.00
226_L245_S1.4721.00
226_L229_L1.4581.00
350_R358_G1.4531.00
235_E246_K1.4431.00
102_A325_L1.4421.00
162_G197_E1.4351.00
320_L324_N1.4131.00
321_I325_L1.4121.00
232_T240_D1.4071.00
82_S266_E1.4031.00
174_A223_V1.3951.00
208_D212_E1.3951.00
157_I173_L1.3891.00
155_A250_N1.3841.00
10_A36_N1.3791.00
7_I18_A1.3791.00
272_N277_T1.3701.00
6_V33_T1.3641.00
3_K102_A1.3591.00
217_S220_K1.3571.00
158_L239_I1.3551.00
66_K70_G1.3501.00
79_E93_A1.3501.00
215_T227_T1.3491.00
327_A332_K1.3291.00
156_T248_V1.3221.00
104_V293_A1.3071.00
322_G326_F1.3041.00
5_I30_A1.3021.00
157_I251_T1.3021.00
13_G314_A1.3011.00
167_V195_L1.2991.00
88_K92_L1.2971.00
157_I191_I1.2971.00
126_L129_A1.2921.00
352_D356_I1.2921.00
276_A292_V1.2921.00
353_A357_I1.2861.00
8_L80_V1.2851.00
67_L71_K1.2791.00
24_H326_F1.2781.00
81_S91_A1.2761.00
174_A192_K1.2751.00
217_S221_R1.2701.00
318_G322_G1.2701.00
281_F324_N1.2681.00
197_E227_T1.2441.00
5_I104_V1.2371.00
201_K208_D1.2361.00
24_H323_Y1.2291.00
129_A133_N1.2061.00
109_S258_V1.2041.00
212_E215_T1.2011.00
92_L98_L1.1841.00
44_I47_L1.1821.00
3_K74_D1.1801.00
8_L107_L1.1761.00
213_R217_S1.1751.00
56_S59_A1.1731.00
226_L247_V1.1721.00
20_T24_H1.1681.00
20_T323_Y1.1651.00
20_T319_E1.1491.00
154_D191_I1.1381.00
175_D221_R1.1301.00
216_A219_E1.1191.00
282_L321_I1.1121.00
293_A321_I1.1071.00
127_K130_A1.1021.00
84_S89_E1.0981.00
234_V252_F1.0951.00
131_D134_K1.0951.00
33_T98_L1.0871.00
133_N136_F1.0811.00
106_G293_A1.0811.00
61_A64_L1.0801.00
81_S93_A1.0771.00
7_I14_G1.0731.00
4_H99_T1.0691.00
229_L242_K1.0681.00
76_K98_L1.0571.00
92_L96_S1.0481.00
241_L247_V1.0371.00
33_T74_D1.0331.00
229_L245_S1.0231.00
68_F71_K1.0221.00
59_A63_P1.0211.00
44_I48_H1.0191.00
55_V58_K1.0161.00
22_R73_I1.0111.00
249_A252_F1.0081.00
282_L297_A1.0081.00
87_K97_T1.0071.00
229_L241_L1.0061.00
78_A94_D1.0031.00
35_V80_V1.0021.00
35_V76_K1.0001.00
8_L105_V0.9951.00
283_Q289_D0.9941.00
216_A220_K0.9891.00
201_K215_T0.9851.00
20_T23_K0.9821.00
156_T191_I0.9801.00
278_V297_A0.9791.00
59_A64_L0.9761.00
122_N236_G0.9761.00
105_V296_S0.9701.00
202_I227_T0.9691.00
21_V322_G0.9671.00
160_G252_F0.9571.00
167_V341_N0.9551.00
238_V241_L0.9541.00
215_T225_F0.9531.00
323_Y328_Y0.9521.00
84_S91_A0.9521.00
162_G202_I0.9501.00
76_K96_S0.9471.00
103_L290_V0.9461.00
17_S318_G0.9411.00
354_V357_I0.9391.00
292_V296_S0.9331.00
277_T285_T0.9221.00
92_L95_G0.9221.00
111_T114_F0.9171.00
197_E204_P0.9151.00
292_V297_A0.9061.00
49_R52_A0.9061.00
130_A134_K0.9051.00
115_G119_L0.9051.00
60_V64_L0.9051.00
123_S234_V0.9011.00
291_F321_I0.8991.00
129_A132_A0.8981.00
194_K249_A0.8961.00
278_V292_V0.8881.00
84_S88_K0.8871.00
132_A136_F0.8861.00
321_I324_N0.8861.00
160_G256_G0.8851.00
213_R216_A0.8851.00
127_K131_D0.8801.00
283_Q324_N0.8771.00
273_R298_V0.8761.00
17_S293_A0.8751.00
3_K31_R0.8731.00
39_P77_I0.8711.00
194_K247_V0.8711.00
39_P78_A0.8691.00
132_A135_V0.8651.00
36_N75_L0.8631.00
10_A34_V0.8621.00
276_A296_S0.8581.00
18_A73_I0.8581.00
287_H290_V0.8571.00
126_L130_A0.8551.00
19_L71_K0.8541.00
61_A65_E0.8481.00
206_L337_F0.8471.00
160_G254_W0.8451.00
337_F347_S0.8451.00
283_Q291_F0.8431.00
59_A62_M0.8421.00
171_G175_D0.8391.00
104_V321_I0.8371.00
158_L247_V0.8311.00
277_T286_S0.8301.00
237_N248_V0.8251.00
271_V277_T0.8241.00
174_A221_R0.8241.00
121_E236_G0.8231.00
291_F325_L0.8231.00
17_S321_I0.8231.00
82_S103_L0.8211.00
126_L132_A0.8211.00
125_V128_S0.8141.00
199_G204_P0.8131.00
170_V195_L0.8081.00
80_V83_F0.8071.00
19_L23_K0.8061.00
78_A93_A0.8041.00
41_H75_L0.8011.00
354_V358_G0.7991.00
65_E69_K0.7991.00
80_V90_V0.7961.00
127_K135_V0.7931.00
57_E133_N0.7891.00
16_L315_W0.7891.00
17_S322_G0.7881.00
14_G106_G0.7851.00
282_L320_L0.7851.00
20_T322_G0.7841.00
5_I325_L0.7821.00
30_A101_D0.7791.00
18_A34_V0.7781.00
283_Q287_H0.7751.00
66_K69_K0.7751.00
319_E323_Y0.7701.00
21_V30_A0.7631.00
313_I317_M0.7631.00
14_G18_A0.7621.00
16_L20_T0.7621.00
102_A328_Y0.7591.00
35_V92_L0.7571.00
83_F97_T0.7551.00
7_I17_S0.7541.00
68_F73_I0.7531.00
201_K212_E0.7511.00
196_V226_L0.7511.00
267_S271_V0.7501.00
112_A115_G0.7491.00
211_I215_T0.7481.00
62_M65_E0.7441.00
116_I119_L0.7441.00
135_V251_T0.7411.00
281_F329_L0.7341.00
351_K354_V0.7301.00
350_R354_V0.7281.00
212_E216_A0.7281.00
316_Q319_E0.7281.00
4_H30_A0.7231.00
6_V103_L0.7201.00
200_P208_D0.7201.00
291_F328_Y0.7191.00
100_Y289_D0.7181.00
13_G106_G0.7181.00
4_H98_L0.7181.00
155_A191_I0.7141.00
278_V282_L0.7121.00
127_K132_A0.7121.00
16_L318_G0.7121.00
206_L347_S0.7111.00
196_V229_L0.7101.00
168_E171_G0.7091.00
38_Y48_H0.7051.00
127_K133_N0.7041.00
155_A192_K0.7021.00
167_V218_L0.7011.00
21_V32_V0.6991.00
159_I166_G0.6941.00
156_T249_A0.6941.00
323_Y327_A0.6931.00
267_S287_H0.6891.00
275_R309_P0.6871.00
85_V88_K0.6871.00
79_E82_S0.6861.00
124_M127_K0.6851.00
196_V241_L0.6791.00
265_G271_V0.6761.00
131_D135_V0.6751.00
218_L225_F0.6741.00
82_S88_K0.6721.00
219_E224_E0.6701.00
128_S132_A0.6691.00
169_L172_E0.6681.00
169_L173_L0.6651.00
22_R72_D0.6651.00
16_L319_E0.6631.00
113_Y119_L0.6621.00
336_T340_V0.6601.00
299_Y308_P0.6591.00
107_L263_L0.6591.00
30_A326_F0.6581.00
262_P265_G0.6581.00
160_G231_V0.6581.00
154_D250_N0.6571.00
114_F254_W0.6571.00
117_P120_E0.6571.00
231_V239_I0.6571.00
67_L70_G0.6561.00
166_G197_E0.6531.00
159_I170_V0.6521.00
86_D287_H0.6521.00
74_D77_I0.6521.00
6_V88_K0.6511.00
165_T255_T0.6511.00
50_L133_N0.6481.00
159_I253_V0.6481.00
279_N285_T0.6471.00
16_L19_L0.6451.00
5_I102_A0.6441.00
22_R32_V0.6441.00
125_V131_D0.6431.00
336_T339_P0.6431.00
202_I215_T0.6421.00
113_Y254_W0.6371.00
262_P271_V0.6361.00
128_S133_N0.6351.00
31_R101_D0.6331.00
134_K137_Q0.6331.00
68_F75_L0.6321.00
133_N137_Q0.6301.00
63_P66_K0.6251.00
328_Y331_G0.6231.00
136_F176_I0.6221.00
119_L254_W0.6211.00
46_E49_R0.6171.00
21_V326_F0.6101.00
335_E339_P0.6091.00
170_V193_L0.6091.00
169_L253_V0.6081.00
314_A318_G0.6071.00
49_R53_G0.6031.00
64_L67_L0.6031.00
102_A329_L0.6001.00
63_P67_L0.6001.00
282_L324_N0.6001.00
280_D331_G0.5991.00
158_L252_F0.5971.00
263_L267_S0.5961.00
17_S21_V0.5951.00
80_V84_S0.5941.00
334_L337_F0.5931.00
260_G275_R0.5931.00
21_V325_L0.5921.00
36_N77_I0.5911.00
29_Q32_V0.5881.00
172_E176_I0.5881.00
37_K261_N0.5861.00
241_L245_S0.5851.00
327_A331_G0.5841.00
110_V262_P0.5821.00
49_R54_N0.5811.00
157_I253_V0.5801.00
45_T50_L0.5781.00
269_L276_A0.5771.00
158_L194_K0.5761.00
62_M66_K0.5761.00
209_D212_E0.5761.00
3_K76_K0.5761.00
126_L135_V0.5751.00
85_V289_D0.5751.00
262_P266_E0.5751.00
14_G34_V0.5741.00
201_K353_A0.5731.00
202_I211_I0.5711.00
335_E340_V0.5701.00
195_L225_F0.5691.00
198_A204_P0.5691.00
126_L131_D0.5691.00
202_I225_F0.5681.00
208_D211_I0.5671.00
89_E92_L0.5651.00
34_V68_F0.5611.00
214_A217_S0.5611.00
81_S84_S0.5611.00
55_V59_A0.5601.00
168_E173_L0.5601.00
167_V225_F0.5601.00
118_G233_N0.5581.00
47_L51_A0.5571.00
295_D314_A0.5561.00
293_A318_G0.5551.00
129_A136_F0.5551.00
123_S126_L0.5551.00
112_A256_G0.5541.00
87_K99_T0.5541.00
12_Y311_A0.5531.00
19_L67_L0.5531.00
136_F139_V0.5511.00
50_L53_G0.5511.00
122_N125_V0.5501.00
124_M251_T0.5501.00
204_P207_P0.5481.00
23_K71_K0.5471.00
7_I32_V0.5451.00
93_A96_S0.5441.00
85_V100_Y0.5431.00
24_H328_Y0.5411.00
224_E227_T0.5391.00
30_A102_A0.5381.00
355_A359_A0.5371.00
5_I17_S0.5351.00
277_T298_V0.5341.00
164_L168_E0.5311.00
312_Q316_Q0.5271.00
157_I193_L0.5271.00
83_F105_V0.5241.00
10_A41_H0.5221.00
248_V251_T0.5181.00
115_G118_G0.5181.00
170_V223_V0.5181.00
166_G255_T0.5161.00
327_A330_E0.5161.00
238_V242_K0.5151.00
311_A314_A0.5141.00
121_E124_M0.5131.00
271_V276_A0.5131.00
271_V274_G0.5111.00
268_G271_V0.5091.00
64_L68_F0.5091.00
12_Y315_W0.5091.00
316_Q320_L0.5081.00
126_L133_N0.5081.00
315_W319_E0.5071.00
310_T313_I0.5071.00
40_T61_A0.5071.00
171_G221_R0.5071.00
113_Y120_E0.5061.00
203_L207_P0.5051.00
275_R298_V0.5051.00
214_A345_L0.5021.00
7_I106_G0.5011.00
203_L214_A0.5011.00
14_G36_N0.5011.00
113_Y125_V0.5011.00
171_G174_A0.5011.00
15_V34_V0.5001.00
334_L339_P0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4g6hA 2 0.9745 100 0.271 Contact Map
4nwzA 2 0.9872 100 0.288 Contact Map
3hywA 4 0.9541 100 0.343 Contact Map
3sx6A 2 0.9617 100 0.351 Contact Map
3h8lA 2 0.8163 100 0.363 Contact Map
1xhcA 1 0.8495 100 0.384 Contact Map
3l8kA 3 0.8827 100 0.385 Contact Map
3kljA 1 0.8571 100 0.386 Contact Map
1lvlA 2 0.8776 100 0.388 Contact Map
3icsA 2 0.9286 100 0.394 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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