6PGD - BACSU - GREMLIN Contacts

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6PGD - 6-phosphogluconate dehydrogenase, NADP(+)-dependent, decarboxylating

UniProt:	P80859	Sequences: MSKQQIGVIGLAVMGKNLALNIESRGFSVSVYNRSSSKTEEFLQEAKGKNVVGTYSIEEFVQSLETPRKILLMVKAGTATDATIQSLLPHLEKDDILIDGGNTYYKDTQRRNKELAESGIHFIGTGVSGGEEGALKGPSIMPGGQKEAHELVKPILEAISAKVDGEPCTTYIGPDGAGHYVKMVHNGIEYGDMQLISESYFILKQVLGLSADELHEVFAEWNKGELDSYLIEITADIFTKKDEETGKPLVDVILDKAGQKGTGKWTSQSALDLGVPLPIITESVFARFISAMKEERVKASGLLSGPEVKPVTENKEELIEAVRKALFMSKICSYAQGFAQMKAASEEYNWDLKYGEIAMIFRGGCIIRAAFLQKIKEAYDREPELDNLLLDSYFKNIVESYQGALRQVISLAVAQGVPVPSFSSALAYYDSYRTAVLPANLIQAQRDYFGAHTYERTDKEGIFHTEWMK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	469 (463)
Sequences:	1779 (909)
Seq/√Len:	42.2

ECOLI - 6PGD
BACSU - 6PGD 6PGDH

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
321_A	407_Q	4.651	1.00
454_Y	465_T	4.182	1.00
85_Q	114_E	3.657	1.00
225_E	323_R	3.599	1.00
109_Q	175_D	3.522	1.00
5_Q	65_E	3.354	1.00
24_S	135_L	3.302	1.00
211_A	248_P	3.155	1.00
57_I	90_H	3.098	1.00
381_R	391_D	3.016	1.00
213_E	315_K	2.911	1.00
352_L	357_I	2.890	1.00
30_S	63_S	2.885	1.00
203_L	322_V	2.866	1.00
210_S	213_E	2.852	1.00
320_E	323_R	2.848	1.00
215_H	239_T	2.789	1.00
412_A	419_V	2.759	1.00
201_F	205_Q	2.722	1.00
43_L	53_G	2.686	1.00
216_E	239_T	2.665	1.00
303_L	429_Y	2.626	1.00
341_M	352_L	2.575	1.00
353_K	356_E	2.533	1.00
153_K	157_E	2.500	1.00
219_A	239_T	2.494	1.00
4_Q	30_S	2.430	1.00
7_G	60_F	2.421	1.00
209_L	217_V	2.419	1.00
163_V	363_G	2.402	1.00
214_L	238_F	2.402	1.00
61_V	90_H	2.397	1.00
96_I	151_L	2.391	1.00
236_D	448_Y	2.383	1.00
249_L	253_I	2.372	1.00
125_T	140_I	2.359	1.00
123_I	152_V	2.321	1.00
289_I	431_S	2.286	1.00
203_L	209_L	2.276	1.00
66_T	92_E	2.251	1.00
295_E	432_Y	2.232	1.00
40_E	55_Y	2.222	1.00
78_T	82_A	2.208	1.00
409_I	413_V	2.204	1.00
174_P	345_S	2.182	1.00
56_S	59_E	2.166	1.00
245_T	252_V	2.145	0.99
27_F	158_A	2.142	0.99
40_E	44_Q	2.133	0.99
324_K	404_A	2.126	0.99
84_I	97_L	2.049	0.99
410_S	414_A	2.049	0.99
212_D	241_K	2.034	0.99
211_A	251_D	2.025	0.99
105_Y	348_Y	2.017	0.99
12_A	75_K	2.009	0.99
58_E	62_Q	1.989	0.99
237_I	444_A	1.986	0.99
328_M	405_L	1.984	0.99
197_S	442_I	1.969	0.99
293_K	297_V	1.928	0.99
409_I	423_S	1.922	0.99
69_K	151_L	1.884	0.99
209_L	319_I	1.859	0.98
374_K	377_E	1.855	0.98
204_K	211_A	1.841	0.98
170_T	356_E	1.826	0.98
314_N	317_E	1.820	0.98
191_G	333_S	1.817	0.98
376_K	380_D	1.812	0.98
23_E	49_K	1.770	0.98
88_L	118_S	1.757	0.98
329_S	422_F	1.755	0.98
19_A	31_V	1.748	0.98
396_N	400_S	1.744	0.98
220_E	223_K	1.741	0.98
298_K	386_D	1.741	0.98
11_L	42_F	1.737	0.98
202_I	318_L	1.721	0.97
423_S	427_A	1.695	0.97
146_K	150_E	1.690	0.97
320_E	324_K	1.669	0.97
84_I	115_L	1.667	0.97
80_T	103_T	1.665	0.97
203_L	214_L	1.655	0.97
88_L	120_I	1.650	0.97
192_D	330_K	1.639	0.97
411_L	414_A	1.632	0.97
6_I	22_I	1.629	0.96
305_G	402_Q	1.618	0.96
407_Q	414_A	1.588	0.96
202_I	322_V	1.575	0.96
166_E	359_M	1.570	0.96
232_E	368_R	1.569	0.96
389_L	398_V	1.567	0.96
247_K	252_V	1.558	0.95
406_R	430_D	1.550	0.95
217_V	319_I	1.548	0.95
199_S	322_V	1.531	0.95
16_K	45_E	1.529	0.95
180_Y	269_S	1.525	0.95
324_K	400_S	1.524	0.95
70_I	97_L	1.515	0.95
270_A	285_F	1.512	0.95
301_G	435_A	1.505	0.94
150_E	153_K	1.487	0.94
132_E	136_K	1.481	0.94
203_L	207_L	1.481	0.94
9_I	32_Y	1.479	0.94
306_P	402_Q	1.477	0.94
31_V	42_F	1.475	0.94
206_V	415_Q	1.466	0.94
321_A	404_A	1.463	0.94
54_T	59_E	1.461	0.94
114_E	117_E	1.456	0.93
25_R	158_A	1.440	0.93
455_E	460_E	1.437	0.93
455_E	462_I	1.437	0.93
112_N	116_A	1.423	0.93
225_E	320_E	1.421	0.93
22_I	71_L	1.419	0.93
220_E	323_R	1.413	0.92
385_L	391_D	1.406	0.92
329_S	405_L	1.405	0.92
36_S	40_E	1.403	0.92
22_I	155_I	1.394	0.92
220_E	316_E	1.384	0.92
300_S	435_A	1.370	0.91
98_I	152_V	1.370	0.91
24_S	136_K	1.369	0.91
278_P	332_C	1.366	0.91
381_R	392_S	1.365	0.91
264_K	272_D	1.358	0.91
339_A	428_Y	1.354	0.91
22_I	29_V	1.352	0.91
30_S	54_T	1.352	0.91
249_L	252_V	1.345	0.90
224_G	323_R	1.345	0.90
355_G	376_K	1.335	0.90
88_L	114_E	1.334	0.90
410_S	413_V	1.333	0.90
207_L	322_V	1.332	0.90
305_G	433_R	1.324	0.90
83_T	86_S	1.316	0.89
215_H	238_F	1.315	0.89
170_T	360_I	1.309	0.89
345_S	354_Y	1.292	0.88
124_G	143_G	1.292	0.88
436_V	457_T	1.286	0.88
11_L	31_V	1.286	0.88
116_A	145_Q	1.282	0.88
355_G	380_D	1.280	0.88
54_T	60_F	1.279	0.88
70_I	91_L	1.274	0.88
328_M	401_Y	1.250	0.87
256_K	455_E	1.242	0.86
344_A	348_Y	1.238	0.86
113_K	117_E	1.238	0.86
54_T	63_S	1.237	0.86
322_V	422_F	1.235	0.86
103_T	107_D	1.232	0.86
241_K	248_P	1.226	0.86
214_L	322_V	1.224	0.86
455_E	461_G	1.222	0.86
8_V	71_L	1.219	0.85
199_S	422_F	1.217	0.85
110_R	114_E	1.213	0.85
281_T	285_F	1.208	0.85
39_T	55_Y	1.190	0.84
73_M	159_I	1.186	0.84
345_S	351_D	1.183	0.84
37_S	41_E	1.177	0.83
46_A	51_V	1.175	0.83
12_A	33_N	1.169	0.83
318_L	411_L	1.151	0.82
4_Q	52_V	1.136	0.81
416_G	433_R	1.135	0.81
34_R	75_K	1.131	0.81
36_S	55_Y	1.129	0.81
219_A	223_K	1.129	0.81
343_A	346_E	1.121	0.80
418_P	434_T	1.120	0.80
184_V	340_Q	1.118	0.80
172_I	360_I	1.114	0.80
184_V	266_T	1.114	0.80
73_M	140_I	1.107	0.79
203_L	217_V	1.102	0.79
23_E	135_L	1.099	0.79
202_I	412_A	1.098	0.79
342_K	346_E	1.098	0.79
20_L	135_L	1.095	0.79
298_K	301_G	1.091	0.78
104_Y	268_Q	1.091	0.78
75_K	79_A	1.089	0.78
303_L	433_R	1.087	0.78
139_S	361_F	1.085	0.78
359_M	376_K	1.085	0.78
227_D	370_A	1.081	0.78
237_I	445_Q	1.078	0.77
33_N	39_T	1.076	0.77
206_V	417_V	1.076	0.77
6_I	98_I	1.071	0.77
158_A	162_K	1.062	0.76
419_V	423_S	1.059	0.76
79_A	82_A	1.059	0.76
273_L	348_Y	1.055	0.76
204_K	251_D	1.055	0.76
121_H	145_Q	1.052	0.76
109_Q	348_Y	1.039	0.75
28_S	50_N	1.037	0.75
18_L	159_I	1.036	0.75
71_L	98_I	1.034	0.74
395_K	399_E	1.031	0.74
16_K	135_L	1.030	0.74
267_S	281_T	1.029	0.74
108_T	124_G	1.028	0.74
413_V	419_V	1.024	0.74
39_T	53_G	1.021	0.73
140_I	160_S	1.015	0.73
35_S	38_K	1.012	0.73
30_S	60_F	1.009	0.73
12_A	34_R	1.008	0.72
172_I	357_I	1.006	0.72
248_P	251_D	1.004	0.72
174_P	351_D	1.000	0.72
8_V	29_V	0.998	0.72
295_E	387_N	0.990	0.71
259_Q	264_K	0.987	0.71
254_L	293_K	0.984	0.71
254_L	456_R	0.983	0.71
109_Q	113_K	0.980	0.70
303_L	306_P	0.978	0.70
70_I	89_P	0.976	0.70
305_G	429_Y	0.972	0.70
438_P	441_L	0.970	0.70
402_Q	433_R	0.965	0.69
273_L	347_E	0.964	0.69
250_V	441_L	0.957	0.69
100_G	140_I	0.956	0.68
60_F	63_S	0.956	0.68
243_E	465_T	0.955	0.68
191_G	279_I	0.952	0.68
38_K	41_E	0.950	0.68
279_I	332_C	0.950	0.68
72_L	97_L	0.949	0.68
123_I	171_Y	0.948	0.68
327_F	397_I	0.948	0.68
201_F	438_P	0.945	0.68
172_I	177_A	0.943	0.67
324_K	401_Y	0.943	0.67
23_E	50_N	0.943	0.67
299_A	432_Y	0.937	0.67
196_I	326_L	0.936	0.67
149_H	153_K	0.935	0.67
149_H	170_T	0.929	0.66
215_H	219_A	0.927	0.66
8_V	31_V	0.926	0.66
434_T	437_L	0.925	0.66
240_K	465_T	0.924	0.66
205_Q	434_T	0.921	0.66
163_V	166_E	0.918	0.65
271_L	284_V	0.916	0.65
335_A	387_N	0.915	0.65
427_A	430_D	0.912	0.65
75_K	78_T	0.910	0.65
413_V	427_A	0.910	0.65
149_H	171_Y	0.909	0.64
28_S	52_V	0.909	0.64
113_K	116_A	0.909	0.64
373_Q	377_E	0.904	0.64
125_T	156_L	0.902	0.64
108_T	122_F	0.901	0.64
220_E	224_G	0.896	0.63
196_I	231_I	0.895	0.63
106_K	272_D	0.888	0.63
112_N	145_Q	0.886	0.62
146_K	171_Y	0.880	0.62
279_I	425_A	0.880	0.62
6_I	71_L	0.880	0.62
16_K	23_E	0.876	0.62
36_S	39_T	0.870	0.61
299_A	390_L	0.869	0.61
146_K	351_D	0.868	0.61
234_T	445_Q	0.866	0.61
203_L	319_I	0.862	0.60
430_D	433_R	0.860	0.60
100_G	127_V	0.858	0.60
166_E	362_R	0.858	0.60
304_S	399_E	0.857	0.60
402_Q	429_Y	0.854	0.60
127_V	140_I	0.853	0.60
96_I	123_I	0.851	0.59
201_F	204_K	0.851	0.59
25_R	162_K	0.850	0.59
240_K	249_L	0.849	0.59
121_H	147_E	0.847	0.59
211_A	250_V	0.846	0.59
125_T	152_V	0.846	0.59
295_E	339_A	0.845	0.59
282_E	421_S	0.845	0.59
317_E	321_A	0.841	0.58
371_F	393_Y	0.839	0.58
303_L	399_E	0.838	0.58
399_E	429_Y	0.837	0.58
143_G	177_A	0.836	0.58
154_P	160_S	0.836	0.58
282_E	285_F	0.835	0.58
343_A	347_E	0.834	0.58
222_N	232_E	0.834	0.58
316_E	320_E	0.834	0.58
207_L	318_L	0.831	0.57
259_Q	268_Q	0.819	0.56
259_Q	288_F	0.819	0.56
418_P	437_L	0.819	0.56
382_E	391_D	0.818	0.56
8_V	11_L	0.818	0.56
115_L	120_I	0.818	0.56
371_F	394_F	0.815	0.56
195_L	421_S	0.813	0.56
413_V	426_L	0.813	0.56
175_D	348_Y	0.808	0.55
327_F	393_Y	0.803	0.55
213_E	216_E	0.798	0.54
270_A	277_L	0.796	0.54
283_S	421_S	0.791	0.54
71_L	100_G	0.790	0.54
61_V	91_L	0.790	0.54
19_A	22_I	0.789	0.54
209_L	315_K	0.789	0.54
281_T	350_W	0.784	0.53
202_I	419_V	0.783	0.53
217_V	238_F	0.781	0.53
439_A	442_I	0.781	0.53
74_V	80_T	0.781	0.53
5_Q	28_S	0.777	0.52
176_G	350_W	0.776	0.52
403_G	407_Q	0.774	0.52
70_I	92_E	0.774	0.52
55_Y	59_E	0.773	0.52
275_V	343_A	0.769	0.52
82_A	86_S	0.768	0.52
104_Y	269_S	0.767	0.52
19_A	51_V	0.766	0.51
327_F	371_F	0.765	0.51
139_S	360_I	0.764	0.51
7_G	10_G	0.761	0.51
140_I	169_T	0.761	0.51
119_G	152_V	0.758	0.51
140_I	152_V	0.756	0.50
148_A	152_V	0.756	0.50
4_Q	28_S	0.755	0.50
116_A	147_E	0.754	0.50
8_V	73_M	0.754	0.50
150_E	154_P	0.753	0.50
19_A	30_S	0.752	0.50
140_I	347_E	0.751	0.50
175_D	349_N	0.750	0.50
206_V	411_L	0.750	0.50
302_L	395_K	0.749	0.50
73_M	229_Y	0.748	0.50
79_A	83_T	0.746	0.50
298_K	390_L	0.746	0.50
356_E	359_M	0.746	0.50
23_E	51_V	0.746	0.50
297_V	435_A	0.743	0.49
341_M	361_F	0.740	0.49
341_M	357_I	0.739	0.49
46_A	49_K	0.737	0.49
58_E	89_P	0.737	0.49
20_L	46_A	0.737	0.49
44_Q	47_K	0.736	0.49
74_V	79_A	0.736	0.49
459_K	462_I	0.733	0.48
33_N	75_K	0.732	0.48
358_A	375_I	0.731	0.48
406_R	416_G	0.728	0.48
273_L	343_A	0.728	0.48
35_S	42_F	0.727	0.48
223_K	247_K	0.725	0.48
294_E	297_V	0.725	0.48
456_R	463_F	0.723	0.47
150_E	171_Y	0.722	0.47
292_M	295_E	0.719	0.47
282_E	424_S	0.719	0.47
211_A	247_K	0.718	0.47
24_S	45_E	0.716	0.47
24_S	49_K	0.716	0.47
249_L	457_T	0.716	0.47
303_L	402_Q	0.715	0.47
65_E	69_K	0.713	0.46
169_T	259_Q	0.712	0.46
109_Q	350_W	0.712	0.46
459_K	463_F	0.709	0.46
269_S	272_D	0.707	0.46
51_V	135_L	0.704	0.46
416_G	430_D	0.703	0.46
20_L	24_S	0.702	0.45
120_I	145_Q	0.702	0.45
377_E	393_Y	0.701	0.45
204_K	379_Y	0.700	0.45
41_E	44_Q	0.700	0.45
232_E	235_A	0.700	0.45
315_K	319_I	0.698	0.45
234_T	441_L	0.697	0.45
273_L	344_A	0.697	0.45
34_R	38_K	0.696	0.45
332_C	369_A	0.696	0.45
344_A	442_I	0.693	0.45
121_H	152_V	0.693	0.45
323_R	401_Y	0.690	0.44
115_L	425_A	0.688	0.44
4_Q	63_S	0.687	0.44
225_E	401_Y	0.687	0.44
62_Q	65_E	0.687	0.44
229_Y	448_Y	0.687	0.44
224_G	362_R	0.687	0.44
242_D	245_T	0.685	0.44
71_L	156_L	0.684	0.44
338_F	442_I	0.684	0.44
243_E	246_G	0.684	0.44
154_P	158_A	0.679	0.43
200_Y	204_K	0.679	0.43
328_M	398_V	0.677	0.43
332_C	405_L	0.676	0.43
209_L	213_E	0.675	0.43
72_L	83_T	0.675	0.43
142_P	170_T	0.675	0.43
245_T	248_P	0.674	0.43
369_A	428_Y	0.674	0.43
374_K	393_Y	0.672	0.43
93_K	147_E	0.670	0.42
429_Y	433_R	0.670	0.42
302_L	392_S	0.670	0.42
33_N	73_M	0.669	0.42
445_Q	448_Y	0.669	0.42
38_K	74_V	0.669	0.42
406_R	427_A	0.668	0.42
256_K	442_I	0.668	0.42
45_E	135_L	0.666	0.42
121_H	151_L	0.664	0.42
299_A	433_R	0.662	0.42
70_I	90_H	0.660	0.42
25_R	136_K	0.660	0.42
56_S	60_F	0.658	0.41
374_K	397_I	0.657	0.41
351_D	354_Y	0.657	0.41
142_P	172_I	0.656	0.41
125_T	169_T	0.655	0.41
338_F	354_Y	0.655	0.41
332_C	335_A	0.654	0.41
338_F	350_W	0.650	0.41
108_T	175_D	0.649	0.41
192_D	196_I	0.649	0.41
109_Q	112_N	0.647	0.40
225_E	327_F	0.647	0.40
229_Y	233_I	0.647	0.40
392_S	395_K	0.646	0.40
201_F	434_T	0.646	0.40
82_A	85_Q	0.644	0.40
330_K	371_F	0.644	0.40
80_T	340_Q	0.644	0.40
85_Q	88_L	0.643	0.40
193_M	445_Q	0.642	0.40
219_A	235_A	0.642	0.40
93_K	118_S	0.642	0.40
220_E	225_E	0.641	0.40
266_T	277_L	0.641	0.40
33_N	38_K	0.640	0.40
195_L	326_L	0.639	0.40
115_L	122_F	0.639	0.40
376_K	398_V	0.639	0.40
318_L	408_V	0.637	0.39
216_E	220_E	0.636	0.39
355_G	371_F	0.636	0.39
254_L	458_D	0.634	0.39
31_V	35_S	0.634	0.39
176_G	192_D	0.634	0.39
285_F	350_W	0.634	0.39
231_I	234_T	0.634	0.39
448_Y	468_M	0.634	0.39
31_V	54_T	0.633	0.39
57_I	86_S	0.629	0.39
323_R	404_A	0.629	0.39
112_N	175_D	0.628	0.39
100_G	156_L	0.628	0.39
438_P	442_I	0.626	0.38
375_I	378_A	0.626	0.38
127_V	445_Q	0.625	0.38
74_V	83_T	0.623	0.38
411_L	415_Q	0.622	0.38
288_F	291_A	0.622	0.38
269_S	340_Q	0.621	0.38
419_V	427_A	0.620	0.38
58_E	90_H	0.620	0.38
163_V	376_K	0.620	0.38
321_A	324_K	0.620	0.38
73_M	135_L	0.620	0.38
116_A	421_S	0.619	0.38
142_P	169_T	0.618	0.38
133_G	141_M	0.618	0.38
282_E	431_S	0.617	0.38
21_N	190_Y	0.617	0.38
75_K	127_V	0.616	0.38
317_E	407_Q	0.616	0.38
88_L	115_L	0.616	0.38
378_A	391_D	0.616	0.38
196_I	330_K	0.615	0.37
328_M	429_Y	0.614	0.37
268_Q	278_P	0.612	0.37
160_S	169_T	0.611	0.37
338_F	393_Y	0.611	0.37
139_S	325_A	0.609	0.37
277_L	332_C	0.608	0.37
201_F	206_V	0.607	0.37
225_E	324_K	0.607	0.37
37_S	40_E	0.607	0.37
156_L	169_T	0.606	0.37
133_G	190_Y	0.606	0.37
135_L	269_S	0.604	0.37
275_V	339_A	0.604	0.37
324_K	328_M	0.600	0.36
397_I	400_S	0.600	0.36
32_Y	57_I	0.598	0.36
25_R	85_Q	0.597	0.36
149_H	157_E	0.596	0.36
255_D	296_R	0.596	0.36
258_G	291_A	0.595	0.36
113_K	309_K	0.595	0.36
16_K	42_F	0.595	0.36
345_S	356_E	0.592	0.35
8_V	19_A	0.591	0.35
103_T	122_F	0.591	0.35
16_K	24_S	0.590	0.35
453_T	465_T	0.589	0.35
211_A	238_F	0.589	0.35
61_V	87_L	0.589	0.35
180_Y	344_A	0.589	0.35
93_K	223_K	0.589	0.35
258_G	268_Q	0.589	0.35
73_M	286_A	0.588	0.35
282_E	286_A	0.588	0.35
398_V	405_L	0.587	0.35
242_D	456_R	0.586	0.35
146_K	174_P	0.586	0.35
404_A	407_Q	0.586	0.35
91_L	97_L	0.586	0.35
306_P	433_R	0.585	0.35
386_D	396_N	0.585	0.35
229_Y	358_A	0.583	0.35
204_K	214_L	0.583	0.35
410_S	418_P	0.582	0.35
295_E	323_R	0.581	0.35
157_E	170_T	0.580	0.34
207_L	319_I	0.579	0.34
42_F	46_A	0.578	0.34
242_D	248_P	0.578	0.34
9_I	57_I	0.577	0.34
42_F	51_V	0.576	0.34
192_D	350_W	0.576	0.34
249_L	466_E	0.576	0.34
39_T	56_S	0.575	0.34
195_L	279_I	0.575	0.34
212_D	248_P	0.574	0.34
170_T	177_A	0.574	0.34
330_K	350_W	0.574	0.34
78_T	417_V	0.574	0.34
27_F	155_I	0.573	0.34
12_A	17_N	0.573	0.34
279_I	421_S	0.572	0.34
313_E	415_Q	0.571	0.34
242_D	252_V	0.571	0.34
155_I	158_A	0.570	0.34
108_T	115_L	0.570	0.34
153_K	170_T	0.570	0.34
320_E	404_A	0.569	0.34
59_E	62_Q	0.569	0.34
258_G	445_Q	0.569	0.34
199_S	202_I	0.568	0.33
57_I	87_L	0.568	0.33
179_H	259_Q	0.566	0.33
89_P	93_K	0.565	0.33
207_L	314_N	0.564	0.33
31_V	166_E	0.563	0.33
39_T	223_K	0.562	0.33
205_Q	417_V	0.562	0.33
22_I	98_I	0.562	0.33
18_L	71_L	0.561	0.33
268_Q	272_D	0.561	0.33
27_F	154_P	0.560	0.33
271_L	281_T	0.560	0.33
174_P	357_I	0.559	0.33
64_L	70_I	0.558	0.33
271_L	285_F	0.558	0.33
174_P	349_N	0.557	0.33
278_P	369_A	0.557	0.33
114_E	118_S	0.556	0.32
196_I	226_L	0.556	0.32
157_E	360_I	0.555	0.32
374_K	391_D	0.555	0.32
11_L	33_N	0.554	0.32
116_A	349_N	0.553	0.32
213_E	314_N	0.551	0.32
208_G	436_V	0.550	0.32
12_A	79_A	0.548	0.32
299_A	406_R	0.547	0.32
264_K	293_K	0.547	0.32
334_Y	394_F	0.547	0.32
12_A	35_S	0.546	0.32
39_T	46_A	0.545	0.32
277_L	281_T	0.544	0.31
201_F	418_P	0.543	0.31
431_S	437_L	0.542	0.31
223_K	384_E	0.542	0.31
338_F	358_A	0.542	0.31
235_A	256_K	0.541	0.31
94_D	119_G	0.541	0.31
69_K	155_I	0.540	0.31
162_K	363_G	0.540	0.31
45_E	49_K	0.540	0.31
27_F	162_K	0.539	0.31
97_L	159_I	0.537	0.31
203_L	318_L	0.537	0.31
188_I	337_G	0.536	0.31
443_Q	446_R	0.535	0.31
214_L	441_L	0.535	0.31
202_I	225_E	0.534	0.31
72_L	148_A	0.533	0.31
104_Y	273_L	0.533	0.31
378_A	394_F	0.533	0.31
105_Y	269_S	0.532	0.30
115_L	118_S	0.532	0.30
214_L	231_I	0.532	0.30
37_S	329_S	0.532	0.30
269_S	275_V	0.531	0.30
406_R	433_R	0.531	0.30
314_N	318_L	0.529	0.30
160_S	166_E	0.528	0.30
297_V	301_G	0.527	0.30
96_I	148_A	0.526	0.30
219_A	308_V	0.526	0.30
264_K	444_A	0.526	0.30
49_K	135_L	0.526	0.30
277_L	340_Q	0.526	0.30
31_V	51_V	0.524	0.30
454_Y	463_F	0.524	0.30
21_N	446_R	0.523	0.30
195_L	327_F	0.523	0.30
210_S	315_K	0.522	0.30
375_I	394_F	0.522	0.30
286_A	431_S	0.522	0.30
131_E	451_A	0.519	0.29
70_I	88_L	0.518	0.29
200_Y	440_N	0.517	0.29
387_N	432_Y	0.517	0.29
23_E	428_Y	0.514	0.29
169_T	350_W	0.514	0.29
177_A	210_S	0.514	0.29
169_T	360_I	0.513	0.29
293_K	435_A	0.513	0.29
20_L	191_G	0.513	0.29
212_D	223_K	0.513	0.29
359_M	363_G	0.513	0.29
79_A	103_T	0.512	0.29
31_V	60_F	0.512	0.29
458_D	463_F	0.511	0.29
54_T	277_L	0.511	0.29
190_Y	263_G	0.511	0.29
135_L	428_Y	0.511	0.29
274_G	288_F	0.509	0.29
180_Y	340_Q	0.509	0.29
31_V	53_G	0.508	0.29
375_I	388_L	0.508	0.29
396_N	399_E	0.507	0.29
20_L	51_V	0.507	0.29
245_T	249_L	0.507	0.29
382_E	385_L	0.506	0.28
79_A	267_S	0.505	0.28
24_S	428_Y	0.505	0.28
327_F	394_F	0.505	0.28
267_S	271_L	0.505	0.28
464_H	467_W	0.505	0.28
65_E	92_E	0.504	0.28
17_N	38_K	0.503	0.28
331_I	389_L	0.502	0.28
61_V	68_R	0.502	0.28
183_M	453_T	0.502	0.28
169_T	431_S	0.501	0.28
226_L	375_I	0.501	0.28
216_E	316_E	0.501	0.28
51_V	112_N	0.500	0.28
284_V	288_F	0.500	0.28
192_D	334_Y	0.500	0.28
12_A	83_T	0.500	0.28
44_Q	197_S	0.500	0.28

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2zydA	2	0.9915	100	0.347	Contact Map
2p4qA	2	0.9915	100	0.353	Contact Map
4gwgA	2	0.9893	100	0.361	Contact Map
1pgjA	2	0.9851	100	0.361	Contact Map
2iz1A	2	0.9957	100	0.365	Contact Map
4e21A	4	0.6375	100	0.785	Contact Map
3dojA	3	0.6077	100	0.851	Contact Map
3pduA	4	0.5991	100	0.853	Contact Map
3pefA	5	0.6034	100	0.854	Contact Map
3ckyA	4	0.6183	100	0.855	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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