GREMLIN Database
G17M - General stress protein 17M
UniProt: P80241 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 115 (105)
Sequences: 155 (126)
Seq/√Len: 12.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
95_R98_E3.8350.99
72_G76_R2.9340.95
34_L53_I2.7410.93
72_G97_D2.7240.93
76_R97_D2.7180.93
33_V44_L2.6500.92
36_H93_E2.3340.86
14_L35_A2.1740.82
36_H97_D2.1730.82
36_H72_G2.0800.78
69_N103_L2.0200.76
45_A50_A1.9670.74
67_I104_F1.9390.73
53_I82_I1.9210.73
34_L41_T1.9000.72
41_T45_A1.8530.70
5_V92_F1.8390.69
32_Y57_E1.7990.67
59_G96_L1.7240.64
72_G93_E1.5880.57
80_H86_E1.5230.54
101_V104_F1.4800.52
15_M19_E1.4450.50
36_H73_D1.4330.49
84_F92_F1.4170.49
66_N89_A1.4170.49
26_V105_V1.4080.48
39_D43_R1.4020.48
93_E97_D1.4010.48
66_N102_L1.3700.46
21_L100_K1.3500.45
45_A52_T1.3220.44
21_L103_L1.3110.43
34_L102_L1.2560.41
54_G57_E1.2410.40
28_K44_L1.2120.38
69_N77_N1.2030.38
8_Y105_V1.1700.36
88_E92_F1.1510.36
28_K65_G1.1070.34
23_K77_N1.1050.33
11_D105_V1.0870.33
36_H76_R1.0740.32
78_K104_F1.0680.32
30_D107_D1.0600.31
65_G69_N1.0570.31
8_Y35_A1.0440.31
73_D88_E1.0440.31
26_V77_N1.0370.30
44_L71_K1.0180.30
16_K20_E1.0130.29
14_L61_K1.0010.29
44_L101_V1.0010.29
25_G66_N0.9910.28
12_E38_D0.9890.28
44_L91_Q0.9870.28
17_D24_M0.9780.28
25_G102_L0.9730.28
36_H75_L0.9720.28
23_K59_G0.9690.28
55_A91_Q0.9610.27
22_Q56_K0.9410.26
58_T74_E0.9240.26
44_L48_T0.9090.25
57_E78_K0.9000.25
63_A82_I0.8700.24
27_A86_E0.8490.23
36_H89_A0.8490.23
30_D65_G0.8440.23
38_D71_K0.8400.23
77_N103_L0.8370.23
28_K92_F0.8230.22
22_Q31_V0.8190.22
42_E86_E0.8120.22
18_V102_L0.7910.21
76_R93_E0.7900.21
85_S98_E0.7890.21
54_G72_G0.7860.21
11_D28_K0.7860.21
7_E95_R0.7840.21
37_D43_R0.7800.21
89_A97_D0.7740.20
5_V65_G0.7700.20
56_K85_S0.7610.20
53_I78_K0.7550.20
6_K51_N0.7490.20
5_V103_L0.7420.19
34_L65_G0.7420.19
25_G100_K0.7370.19
50_A79_I0.7340.19
8_Y11_D0.7300.19
79_I102_L0.7270.19
17_D20_E0.7250.19
19_E63_A0.7240.19
19_E32_Y0.7180.19
69_N92_F0.7180.19
6_K84_F0.7160.19
62_H95_R0.7140.18
10_N21_L0.7080.18
46_D49_N0.7070.18
23_K31_V0.7050.18
8_Y81_E0.6900.18
19_E88_E0.6850.18
49_N58_T0.6840.18
48_T79_I0.6840.18
54_G97_D0.6830.18
104_F108_N0.6760.17
62_H92_F0.6640.17
87_D104_F0.6620.17
85_S100_K0.6610.17
96_L99_G0.6610.17
37_D52_T0.6580.17
34_L101_V0.6430.16
6_K102_L0.6370.16
24_M85_S0.6360.16
39_D55_A0.6310.16
16_K19_E0.6300.16
41_T78_K0.6280.16
4_V101_V0.6200.16
4_V24_M0.6200.16
20_E103_L0.6180.16
58_T65_G0.6150.16
41_T74_E0.6070.15
18_V61_K0.6060.15
53_I68_F0.6050.15
66_N69_N0.6010.15
5_V96_L0.5970.15
54_G89_A0.5950.15
52_T70_K0.5950.15
55_A60_F0.5930.15
75_L93_E0.5890.15
56_K88_E0.5880.15
44_L100_K0.5850.15
6_K17_D0.5830.15
7_E81_E0.5780.15
29_E105_V0.5770.15
27_A30_D0.5680.14
67_I87_D0.5640.14
33_V46_D0.5590.14
75_L89_A0.5530.14
32_Y49_N0.5520.14
30_D108_N0.5500.14
23_K86_E0.5480.14
17_D105_V0.5440.14
33_V45_A0.5430.14
62_H81_E0.5370.14
42_E52_T0.5330.14
17_D98_E0.5260.13
42_E90_A0.5260.13
65_G103_L0.5190.13
24_M98_E0.5170.13
25_G67_I0.5120.13
87_D91_Q0.5090.13
6_K61_K0.5050.13
67_I92_F0.5020.13
35_A71_K0.5020.13
62_H101_V0.5010.13
13_Q46_D0.5000.13
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3m66A 1 0.9304 62.8 0.914 Contact Map
4pevA 1 0.9913 44.6 0.923 Contact Map
3gt0A 3 0.8522 43.7 0.923 Contact Map
2rcyA 5 0.8348 37.3 0.926 Contact Map
4wjiA 2 0.8696 36.3 0.927 Contact Map
3triA 2 0.8696 29.4 0.93 Contact Map
4pz0A 1 0.9913 28.5 0.931 Contact Map
4m9dA 2 0.9565 24.8 0.933 Contact Map
3etfA 3 0.8174 23.2 0.934 Contact Map
3mvaO 1 0.9652 23.1 0.934 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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