GREMLIN Database
URE1 - Urease subunit alpha
UniProt: P77837 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 569 (564)
Sequences: 1096 (350)
Seq/√Len: 14.8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
87_V129_L6.6551.00
29_I402_A6.2651.00
31_V75_V5.5401.00
20_I75_V4.8501.00
419_L423_V4.7431.00
69_L179_Y4.6191.00
288_M538_I4.4961.00
77_L402_A4.4631.00
359_M416_T3.7281.00
382_D386_K3.6410.99
29_I77_L3.6070.99
209_I241_E3.6000.99
23_G562_L3.5710.99
221_L227_T3.4840.99
69_L89_V3.3880.99
120_E165_A3.2930.99
80_T83_V3.2460.99
426_V434_L3.1380.98
239_V246_V2.9950.98
393_G400_V2.9620.98
299_S359_M2.8870.97
403_K529_L2.8650.97
50_I115_I2.8550.97
79_Y528_K2.8400.97
71_I124_G2.8390.97
187_A196_F2.7630.96
26_D386_K2.7590.96
93_R422_E2.7510.96
422_E514_S2.7080.96
560_V563_G2.7030.96
129_L434_L2.6710.95
40_E106_M2.6220.95
491_I514_S2.6130.95
67_L113_M2.6060.95
221_L231_A2.5830.94
182_R185_E2.5510.94
146_M190_F2.5370.94
496_Q500_E2.4080.92
297_L359_M2.4040.92
76_L97_V2.3950.92
184_L509_L2.3890.92
157_L192_I2.3200.90
305_I360_T2.2930.90
444_V562_L2.2780.90
382_D561_P2.2740.90
547_A552_L2.2580.89
557_V560_V2.2350.89
274_Y360_T2.2300.89
499_I513_I2.2280.89
74_V129_L2.2230.88
157_L370_V2.2130.88
305_I380_V2.2030.88
431_L491_I2.1590.87
181_A507_L2.1590.87
43_I326_D2.1510.87
151_S457_R2.1500.87
195_G217_I2.1470.87
502_G505_E2.1140.86
23_G444_V2.0990.85
77_L406_I2.0850.85
146_M192_I2.0540.84
133_G154_V2.0430.84
263_L290_L2.0420.84
494_M504_A2.0340.83
188_E511_K2.0180.83
129_L436_L2.0140.83
378_W409_Y2.0000.82
70_V100_S1.9980.82
138_I157_L1.9810.82
115_I121_V1.9670.81
259_L263_L1.9630.81
67_L121_V1.9520.81
69_L122_I1.9190.79
133_G374_I1.9060.79
190_F482_Y1.8940.79
30_E397_N1.8820.78
129_L426_V1.8810.78
484_K510_E1.8630.77
415_I522_L1.8570.77
490_S511_K1.8500.77
67_L95_V1.8480.77
350_I554_C1.8430.77
62_G90_K1.8300.76
168_S250_T1.8300.76
421_H514_S1.8270.76
197_L274_Y1.8270.76
494_M503_V1.7960.75
158_L419_L1.7670.73
197_L247_A1.7620.73
291_A536_I1.7600.73
213_E501_R1.7520.73
459_Q475_M1.7490.73
201_N227_T1.7290.72
546_F551_E1.7230.71
97_V428_K1.7140.71
138_I145_Q1.7060.71
179_Y454_M1.6920.70
127_K438_D1.6870.70
74_V87_V1.6790.69
87_V436_L1.6740.69
62_G65_G1.6720.69
180_M216_A1.6500.68
110_D113_M1.6490.68
19_K397_N1.6480.68
166_T169_K1.6370.67
288_M357_I1.6360.67
76_L85_A1.6350.67
444_V567_F1.6350.67
337_H356_A1.6350.67
165_A455_I1.6320.67
181_A185_E1.6270.67
67_L96_G1.6240.67
187_A194_V1.6130.66
233_K237_E1.6130.66
229_P256_A1.6100.66
136_T299_S1.6100.66
274_Y299_S1.6090.66
421_H517_K1.6090.66
537_E546_F1.5780.64
16_T83_V1.5750.64
299_S416_T1.5730.64
63_K177_A1.5620.64
387_Q554_C1.5590.63
197_L218_G1.5520.63
131_A406_I1.5490.63
291_A356_A1.5370.62
83_V528_K1.5290.62
152_S374_I1.5230.62
82_I403_K1.5170.61
79_Y529_L1.5130.61
390_A394_E1.5120.61
67_L88_G1.5110.61
58_G104_D1.5030.61
494_M499_I1.5010.60
498_S504_A1.4950.60
518_N521_K1.4740.59
250_T273_T1.4650.58
19_K30_E1.4590.58
350_I552_L1.4580.58
233_K267_G1.4530.58
96_G110_D1.4490.58
62_G91_D1.4360.57
205_K234_T1.4350.57
136_T360_T1.4310.57
454_M489_T1.4290.57
503_V513_I1.4250.56
80_T528_K1.4020.55
544_Q551_E1.3830.54
89_V179_Y1.3810.54
221_L248_I1.3800.54
162_T175_S1.3790.54
518_N522_L1.3650.53
259_L289_K1.3590.53
276_I290_L1.3550.52
3_M11_L1.3360.51
144_Q460_M1.3340.51
138_I370_V1.3300.51
73_N125_E1.3290.51
382_D560_V1.3250.51
499_I504_A1.3240.51
145_Q370_V1.3210.51
185_E488_S1.3130.50
44_F170_A1.3100.50
187_A486_N1.3080.50
69_L454_M1.3060.50
146_M194_V1.3060.50
37_V40_E1.3010.49
491_I513_I1.2990.49
124_G129_L1.2950.49
407_A529_L1.2890.49
421_H515_P1.2890.49
519_I522_L1.2850.49
117_A207_P1.2810.48
375_I567_F1.2800.48
248_I273_T1.2750.48
96_G113_M1.2740.48
11_L43_I1.2620.47
158_L217_I1.2620.47
227_T231_A1.2600.47
50_I121_V1.2550.47
276_I291_A1.2520.47
178_W454_M1.2500.47
189_E486_N1.2450.46
422_E515_P1.2390.46
402_A406_I1.2370.46
145_Q157_L1.2330.46
136_T359_M1.2330.46
42_M115_I1.2320.46
19_K28_W1.2240.45
499_I515_P1.2230.45
360_T380_V1.2200.45
42_M106_M1.2150.45
106_M511_K1.2140.45
263_L293_Y1.2120.44
213_E242_A1.2080.44
49_T55_G1.2060.44
209_I242_A1.1970.44
219_L244_I1.1950.44
181_A506_S1.1910.43
42_M100_S1.1850.43
494_M513_I1.1820.43
74_V436_L1.1790.43
80_T529_L1.1740.42
27_L402_A1.1680.42
76_L129_L1.1640.42
445_K567_F1.1630.42
11_L326_D1.1610.42
201_N221_L1.1540.41
427_E430_K1.1530.41
274_Y416_T1.1520.41
227_T248_I1.1470.41
499_I503_V1.1450.41
212_V219_L1.1440.41
52_D203_S1.1410.41
452_G489_T1.1380.40
240_D266_I1.1350.40
151_S459_Q1.1280.40
42_M50_I1.1220.40
110_D114_V1.1210.40
240_D522_L1.1190.39
276_I357_I1.1180.39
560_V564_Q1.1150.39
126_G152_S1.1120.39
50_I106_M1.1050.39
96_G428_K1.1030.39
134_V419_L1.1020.39
127_K447_E1.0960.38
138_I274_Y1.0790.37
184_L492_T1.0760.37
415_I528_K1.0740.37
393_G396_G1.0740.37
168_S201_N1.0730.37
6_E10_E1.0700.37
37_V108_G1.0700.37
559_Y563_G1.0660.37
559_Y562_L1.0650.37
127_K436_L1.0560.36
166_T448_L1.0550.36
12_F43_I1.0510.36
266_I296_I1.0480.36
122_I450_L1.0460.36
35_F83_V1.0450.36
42_M113_M1.0390.35
375_I444_V1.0380.35
387_Q555_Q1.0380.35
388_R550_E1.0370.35
268_D523_S1.0310.35
170_A315_H1.0280.35
483_G486_N1.0280.35
357_I538_I1.0270.35
170_A311_T1.0250.35
7_E10_E1.0250.35
356_A533_L1.0220.34
3_M12_F1.0200.34
189_E482_Y1.0190.34
40_E107_D1.0190.34
438_D447_E1.0190.34
465_A479_Y1.0170.34
221_L235_C1.0130.34
497_A501_R1.0100.34
319_M340_I1.0090.34
415_I420_S1.0070.34
87_V434_L1.0040.34
383_K387_Q1.0010.33
311_T315_H1.0010.33
449_V475_M0.9990.33
176_G211_Q0.9950.33
176_G179_Y0.9940.33
138_I364_S0.9940.33
412_N528_K0.9900.33
117_A202_A0.9900.33
292_S407_A0.9840.33
250_T287_I0.9840.33
188_E487_R0.9800.32
264_D267_G0.9780.32
356_A547_A0.9630.32
400_V529_L0.9570.31
456_A490_S0.9560.31
151_S475_M0.9540.31
172_T199_K0.9530.31
359_M527_M0.9510.31
205_K237_E0.9490.31
57_N104_D0.9490.31
290_L357_I0.9470.31
291_A357_I0.9450.31
63_K66_A0.9440.31
157_L194_V0.9400.30
93_R431_L0.9400.30
230_S234_T0.9350.30
209_I213_E0.9300.30
480_A489_T0.9290.30
80_T403_K0.9290.30
23_G375_I0.9150.29
380_V383_K0.9110.29
315_H340_I0.9080.29
383_K554_C0.9050.29
120_E167_G0.9040.29
79_Y83_V0.9040.29
415_I521_K0.9020.29
273_T276_I0.9010.29
312_M337_H0.9000.29
350_I388_R0.8990.29
294_A523_S0.8990.29
131_A426_V0.8980.28
44_F315_H0.8980.28
166_T447_E0.8970.28
89_V122_I0.8970.28
346_A554_C0.8960.28
80_T426_V0.8930.28
322_C465_A0.8890.28
44_F311_T0.8840.28
120_E162_T0.8780.28
504_A513_I0.8750.27
106_M204_D0.8720.27
326_D329_V0.8720.27
192_I449_V0.8710.27
150_L457_R0.8660.27
252_T543_Y0.8650.27
221_L299_S0.8630.27
266_I290_L0.8620.27
144_Q463_P0.8570.27
379_Q470_P0.8530.26
66_A117_A0.8520.26
106_M474_F0.8510.26
190_F194_V0.8490.26
536_I547_A0.8470.26
69_L165_A0.8470.26
88_G113_M0.8460.26
370_V470_P0.8460.26
498_S507_L0.8450.26
559_Y565_R0.8440.26
374_I409_Y0.8420.26
232_I248_I0.8390.26
42_M67_L0.8380.26
242_A497_A0.8360.26
425_S430_K0.8330.26
77_L82_I0.8320.26
400_V403_K0.8310.26
392_A400_V0.8300.25
378_W443_G0.8290.25
93_R512_R0.8270.25
512_R515_P0.8270.25
146_M157_L0.8250.25
350_I383_K0.8250.25
357_I457_R0.8230.25
380_V478_M0.8190.25
141_I168_S0.8190.25
527_M531_S0.8170.25
221_L305_I0.8160.25
150_L456_A0.8120.25
498_S503_V0.8110.25
110_D182_R0.8110.25
227_T322_C0.8110.25
343_A543_Y0.8080.25
207_P210_E0.8080.25
417_H569_F0.8030.24
422_E512_R0.8020.24
169_K468_P0.8010.24
178_W182_R0.8000.24
457_R477_Q0.7990.24
305_I383_K0.7980.24
108_G113_M0.7980.24
299_S360_T0.7970.24
317_D322_C0.7950.24
346_A553_S0.7920.24
340_I349_D0.7920.24
151_S449_V0.7910.24
53_G243_D0.7890.24
144_Q473_V0.7880.24
67_L342_A0.7840.24
79_Y403_K0.7810.23
447_E459_Q0.7800.23
76_L89_V0.7790.23
321_V469_T0.7790.23
502_G532_A0.7780.23
505_E508_G0.7760.23
196_F560_V0.7760.23
70_V115_I0.7730.23
292_S533_L0.7720.23
187_A492_T0.7690.23
204_D207_P0.7680.23
141_I478_M0.7680.23
501_R504_A0.7670.23
188_E509_L0.7670.23
49_T291_A0.7660.23
93_R514_S0.7640.23
106_M274_Y0.7630.23
195_G483_G0.7630.23
168_S227_T0.7630.23
379_Q483_G0.7620.23
386_K557_V0.7620.23
19_K484_K0.7620.23
532_A548_D0.7610.23
270_V523_S0.7600.23
390_A393_G0.7580.23
4_S7_E0.7570.23
274_Y359_M0.7570.23
431_L451_K0.7560.22
494_M515_P0.7560.22
324_H331_E0.7550.22
423_V491_I0.7540.22
288_M291_A0.7540.22
227_T299_S0.7530.22
113_M342_A0.7530.22
315_H349_D0.7520.22
273_T333_V0.7520.22
289_K293_Y0.7490.22
273_T297_L0.7490.22
154_V374_I0.7480.22
321_V468_P0.7450.22
346_A527_M0.7450.22
97_V131_A0.7450.22
173_C270_V0.7430.22
422_E458_A0.7410.22
535_K559_Y0.7410.22
240_D521_K0.7400.22
162_T165_A0.7390.22
123_S324_H0.7360.22
59_R104_D0.7350.22
299_S527_M0.7340.22
394_E400_V0.7330.22
62_G177_A0.7300.21
330_P548_D0.7300.21
70_V208_L0.7290.21
52_D58_G0.7290.21
450_L525_L0.7280.21
20_I31_V0.7270.21
188_E483_G0.7220.21
504_A507_L0.7210.21
261_N264_D0.7210.21
240_D533_L0.7200.21
3_M475_M0.7180.21
252_T538_I0.7170.21
30_E394_E0.7170.21
85_A428_K0.7160.21
140_F196_F0.7160.21
463_P478_M0.7160.21
329_V333_V0.7150.21
203_S243_D0.7140.21
312_M342_A0.7100.21
390_A395_N0.7090.21
456_A481_S0.7070.21
16_T33_K0.7060.21
247_A417_H0.7050.21
305_I456_A0.7040.21
85_A97_V0.7030.21
105_I192_I0.7030.21
259_L290_L0.7020.20
287_I290_L0.7020.20
174_T366_A0.7010.20
46_G321_V0.7000.20
113_M541_K0.6990.20
384_M554_C0.6960.20
76_L428_K0.6960.20
495_S516_V0.6960.20
59_R202_A0.6950.20
375_I450_L0.6940.20
28_W82_I0.6930.20
167_G366_A0.6920.20
349_D383_K0.6920.20
229_P235_C0.6920.20
374_I378_W0.6910.20
266_I494_M0.6880.20
28_W397_N0.6870.20
415_I518_N0.6860.20
248_I287_I0.6850.20
274_Y417_H0.6840.20
185_E484_K0.6840.20
340_I467_I0.6840.20
498_S506_S0.6840.20
150_L192_I0.6840.20
106_M382_D0.6820.20
26_D382_D0.6820.20
239_V379_Q0.6820.20
73_N343_A0.6800.20
264_D497_A0.6780.20
110_D541_K0.6780.20
124_G436_L0.6770.20
240_D520_R0.6770.20
459_Q474_F0.6770.20
16_T19_K0.6760.20
320_M333_V0.6750.20
212_V244_I0.6750.20
40_E109_V0.6740.19
371_G465_A0.6740.19
373_V377_T0.6740.19
445_K483_G0.6730.19
294_A533_L0.6720.19
310_N317_D0.6720.19
312_M345_I0.6710.19
25_T562_L0.6710.19
356_A534_P0.6700.19
46_G253_I0.6700.19
33_K496_Q0.6690.19
65_G91_D0.6680.19
167_G478_M0.6670.19
148_V407_A0.6660.19
90_K114_V0.6660.19
195_G445_K0.6630.19
265_A452_G0.6610.19
189_E487_R0.6610.19
87_V403_K0.6600.19
522_L533_L0.6590.19
87_V426_V0.6580.19
202_A208_L0.6570.19
117_A511_K0.6570.19
501_R506_S0.6570.19
58_G106_M0.6560.19
144_Q477_Q0.6550.19
74_V124_G0.6540.19
40_E88_G0.6530.19
31_V89_V0.6520.19
516_V519_I0.6520.19
292_S536_I0.6500.19
52_D202_A0.6480.19
463_P476_R0.6480.19
449_V457_R0.6470.19
260_E388_R0.6460.19
302_T337_H0.6450.18
62_G66_A0.6440.18
535_K548_D0.6430.18
144_Q478_M0.6430.18
12_F402_A0.6430.18
118_G177_A0.6420.18
36_T125_E0.6410.18
462_D470_P0.6400.18
431_L514_S0.6390.18
431_L506_S0.6380.18
379_Q441_F0.6370.18
134_V423_V0.6360.18
136_T480_A0.6360.18
7_E307_Y0.6360.18
319_M324_H0.6350.18
145_Q365_Q0.6340.18
49_T165_A0.6340.18
175_S319_M0.6330.18
56_Q467_I0.6330.18
196_F289_K0.6330.18
38_Y243_D0.6320.18
237_E267_G0.6310.18
227_T459_Q0.6310.18
131_A428_K0.6310.18
133_G138_I0.6300.18
525_L531_S0.6300.18
327_A384_M0.6300.18
459_Q473_V0.6300.18
140_F195_G0.6280.18
273_T287_I0.6280.18
66_A182_R0.6280.18
35_F85_A0.6270.18
449_V532_A0.6270.18
431_L477_Q0.6260.18
80_T131_A0.6250.18
88_G201_N0.6250.18
173_C203_S0.6240.18
151_S234_T0.6230.18
127_K166_T0.6230.18
115_I393_G0.6220.18
406_I428_K0.6190.18
377_T409_Y0.6190.18
168_S366_A0.6170.18
263_L266_I0.6170.18
240_D540_P0.6170.18
100_S113_M0.6160.18
362_S373_V0.6160.18
134_V154_V0.6160.18
247_A256_A0.6150.17
496_Q517_K0.6150.17
67_L258_F0.6140.17
49_T88_G0.6130.17
370_V384_M0.6130.17
377_T439_P0.6130.17
328_K360_T0.6130.17
63_K515_P0.6120.17
312_M471_E0.6120.17
108_G229_P0.6110.17
170_A340_I0.6100.17
422_E491_I0.6100.17
145_Q462_D0.6090.17
379_Q568_L0.6080.17
167_G380_V0.6080.17
63_K207_P0.6070.17
53_G203_S0.6070.17
23_G559_Y0.6060.17
95_V113_M0.6060.17
261_N356_A0.6060.17
95_V428_K0.6050.17
309_V465_A0.6040.17
203_S234_T0.6040.17
2_K76_L0.6040.17
126_G439_P0.6040.17
186_A485_A0.6020.17
234_T237_E0.6020.17
213_E458_A0.6010.17
158_L197_L0.6000.17
148_V239_V0.5990.17
133_G409_Y0.5980.17
55_G274_Y0.5980.17
87_V124_G0.5970.17
333_V396_G0.5970.17
266_I271_I0.5970.17
481_S490_S0.5960.17
31_V126_G0.5960.17
350_I387_Q0.5950.17
44_F349_D0.5950.17
42_M519_I0.5950.17
235_C246_V0.5930.17
157_L320_M0.5920.17
360_T471_E0.5910.17
28_W421_H0.5910.17
379_Q565_R0.5900.17
189_E402_A0.5900.17
192_I431_L0.5890.17
12_F536_I0.5880.17
557_V563_G0.5880.17
43_I72_T0.5880.17
270_V522_L0.5870.17
188_E356_A0.5870.17
82_I233_K0.5870.17
243_D496_Q0.5860.17
33_K80_T0.5860.17
359_M560_V0.5850.17
158_L195_G0.5850.17
67_L327_A0.5840.17
67_L541_K0.5840.17
71_I129_L0.5840.17
258_F555_Q0.5840.17
288_M397_N0.5830.16
320_M331_E0.5810.16
371_G464_N0.5780.16
403_K528_K0.5770.16
232_I271_I0.5770.16
122_I165_A0.5770.16
416_T500_E0.5760.16
535_K557_V0.5760.16
311_T349_D0.5750.16
38_Y99_K0.5750.16
138_I168_S0.5750.16
299_S337_H0.5740.16
53_G343_A0.5740.16
293_Y533_L0.5740.16
168_S364_S0.5740.16
194_V564_Q0.5730.16
219_L343_A0.5730.16
185_E507_L0.5730.16
311_T340_I0.5730.16
456_A489_T0.5720.16
308_T379_Q0.5720.16
171_T366_A0.5720.16
26_D385_K0.5720.16
243_D518_N0.5710.16
180_M211_Q0.5710.16
170_A373_V0.5700.16
217_I569_F0.5690.16
345_I479_Y0.5690.16
454_M480_A0.5690.16
315_H377_T0.5680.16
20_I74_V0.5680.16
188_E357_I0.5670.16
167_G468_P0.5670.16
288_M292_S0.5660.16
412_N527_M0.5660.16
194_V479_Y0.5660.16
400_V475_M0.5660.16
64_D510_E0.5660.16
24_D379_Q0.5650.16
535_K547_A0.5650.16
546_F550_E0.5650.16
99_K109_V0.5640.16
55_G106_M0.5640.16
385_K398_D0.5630.16
235_C250_T0.5630.16
267_G296_I0.5620.16
177_A181_A0.5620.16
158_L449_V0.5620.16
4_S261_N0.5610.16
276_I370_V0.5610.16
415_I523_S0.5600.16
289_K537_E0.5590.16
263_L474_F0.5590.16
308_T425_S0.5580.16
100_S115_I0.5580.16
16_T30_E0.5570.16
415_I531_S0.5570.16
274_Y361_S0.5560.16
46_G338_S0.5550.16
297_L416_T0.5550.16
150_L227_T0.5540.16
122_I448_L0.5530.16
202_A207_P0.5530.16
293_Y359_M0.5530.16
378_W402_A0.5520.16
170_A467_I0.5520.16
198_G219_L0.5520.16
209_I480_A0.5500.15
66_A312_M0.5500.15
498_S501_R0.5490.15
62_G118_G0.5490.15
19_K390_A0.5490.15
107_D474_F0.5480.15
166_T235_C0.5480.15
108_G268_D0.5480.15
485_A488_S0.5470.15
36_T82_I0.5470.15
9_A237_E0.5470.15
552_L568_L0.5460.15
146_M471_E0.5450.15
250_T450_L0.5450.15
154_V452_G0.5440.15
146_M527_M0.5440.15
109_V184_L0.5430.15
93_R421_H0.5420.15
55_G99_K0.5420.15
74_V552_L0.5410.15
492_T507_L0.5410.15
327_A507_L0.5410.15
87_V97_V0.5400.15
171_T380_V0.5400.15
35_F38_Y0.5390.15
67_L108_G0.5390.15
67_L428_K0.5390.15
227_T460_M0.5380.15
146_M150_L0.5380.15
234_T238_V0.5370.15
35_F76_L0.5360.15
7_E471_E0.5360.15
12_F38_Y0.5360.15
390_A397_N0.5360.15
247_A470_P0.5360.15
197_L288_M0.5350.15
148_V259_L0.5350.15
146_M189_E0.5350.15
260_E319_M0.5340.15
79_Y127_K0.5340.15
9_A240_D0.5330.15
315_H467_I0.5330.15
479_Y567_F0.5320.15
37_V107_D0.5320.15
170_A377_T0.5310.15
458_A478_M0.5310.15
382_D563_G0.5310.15
292_S337_H0.5300.15
205_K241_E0.5300.15
366_A380_V0.5290.15
173_C221_L0.5280.15
488_S500_E0.5280.15
80_T427_E0.5270.15
463_P473_V0.5270.15
250_T274_Y0.5270.15
201_N305_I0.5260.15
266_I291_A0.5260.15
116_G131_A0.5260.15
188_E507_L0.5260.15
422_E517_K0.5260.15
170_A378_W0.5260.15
144_Q365_Q0.5250.15
443_G562_L0.5250.15
44_F56_Q0.5240.15
316_L324_H0.5240.15
539_D544_Q0.5230.15
118_G210_E0.5230.15
91_D227_T0.5230.15
90_K546_F0.5230.15
536_I542_T0.5220.15
375_I523_S0.5220.15
161_G199_K0.5220.15
142_C168_S0.5220.15
334_A543_Y0.5210.15
44_F340_I0.5210.15
65_G90_K0.5210.15
487_R510_E0.5210.15
463_P474_F0.5210.15
305_I350_I0.5200.15
184_L507_L0.5200.15
23_G560_V0.5190.15
234_T307_Y0.5190.15
157_L479_Y0.5180.15
136_T417_H0.5180.15
148_V490_S0.5170.15
258_F263_L0.5170.15
185_E386_K0.5170.15
38_Y53_G0.5160.15
313_D459_Q0.5160.15
261_N507_L0.5160.15
64_D392_A0.5160.15
378_W406_I0.5150.15
243_D343_A0.5150.15
219_L361_S0.5150.15
19_K396_G0.5150.15
211_Q564_Q0.5140.14
138_I227_T0.5140.14
290_L459_Q0.5140.14
46_G335_F0.5130.14
95_V342_A0.5120.14
212_V287_I0.5120.14
293_Y535_K0.5120.14
219_L543_Y0.5120.14
100_S377_T0.5120.14
397_N483_G0.5110.14
148_V356_A0.5110.14
502_G540_P0.5110.14
360_T554_C0.5110.14
195_G419_L0.5110.14
500_E505_E0.5110.14
253_I325_L0.5100.14
188_E484_K0.5100.14
12_F276_I0.5100.14
491_I512_R0.5100.14
57_N519_I0.5090.14
436_L518_N0.5090.14
177_A506_S0.5090.14
253_I302_T0.5080.14
180_M503_V0.5080.14
52_D243_D0.5080.14
145_Q154_V0.5080.14
84_K545_V0.5080.14
192_I491_I0.5080.14
250_T345_I0.5070.14
290_L293_Y0.5070.14
165_A563_G0.5070.14
190_F196_F0.5060.14
136_T221_L0.5060.14
351_L356_A0.5060.14
186_A192_I0.5050.14
90_K110_D0.5050.14
274_Y540_P0.5050.14
79_Y569_F0.5050.14
365_Q460_M0.5040.14
36_T99_K0.5040.14
42_M274_Y0.5040.14
313_D331_E0.5030.14
221_L360_T0.5030.14
67_L350_I0.5030.14
148_V166_T0.5020.14
74_V373_V0.5020.14
375_I562_L0.5020.14
120_E161_G0.5020.14
168_S479_Y0.5010.14
19_K420_S0.5010.14
170_A349_D0.5010.14
12_F551_E0.5010.14
555_Q559_Y0.5010.14
221_L342_A0.5000.14
311_T467_I0.5000.14
247_A456_A0.5000.14
12_F456_A0.5000.14
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4ep8C 3 0.993 100 0.441 Contact Map
4gy7A 3 0.9982 100 0.445 Contact Map
4ac7C 3 1 100 0.472 Contact Map
1e9yB 4 0.9965 100 0.483 Contact Map
3sfwA 3 0.6573 100 0.901 Contact Map
1gkpA 4 0.6555 100 0.903 Contact Map
4lcqA 3 0.6872 100 0.903 Contact Map
4c65A 6 0.6327 100 0.903 Contact Map
1xrtA 1 0.5677 100 0.903 Contact Map
3be7A 5 0.5835 100 0.903 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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