LUTP - BACSU - GREMLIN Contacts

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LUTP - L-lactate permease

UniProt:	P71067	Sequences: MQWTQAYTPIGGNLLLSALAALVPIIFFFWALAIKRMKGYTAGLATLGIALIIAVLVYRMPAEKALMSATQGAVYGLLPIGWIIVTSVFLYKITVKTGQFDIIRSSVLSITDDRRLQALLIAFSFGAFLEGAAGFGAPVAISAALLVGLGFNPLYAAGICLIANTAPVAFGAIGIPITAVEGPTGIPAMEISQMVGRQLPFLSVFIPLYLIIIMSGFRKALEIWPAILVSGVSFAVVQYLSSNFLGPELPDVLSALVSMAALAVFLKWWKPKTTFRFAGEQESAASIETARTNPAAPAYRGGQIFKAWSPFLLLTAMISVWGIPSVKSALTGHYEGSAVFLKWLNAVGEKLTFSPGVPFLNNQIVNADGTPIEAVYKLEVLGSAGTAILIAAVLSKFITAISWKDWGTVFKETVQELKLPILTIASVVGFAYVTNSSGMSTTLGMTLALTGSMFTFFSPVLGWLGVFITGSDTSANLLFGNLQKVTALSVGMDPVLSVAANSSGGVTGKMISPQSIAVACAAVGLAGKESDLFRFTIKHSLFLLLLVCIITFLQHHVFSWMIP	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	563 (504)
Sequences:	1571 (990)
Seq/√Len:	44.1

ECOLI - GLCA LLDP
BACSU - LUTP LCTP
HALSA - Q9HHI2
SULSO - Q7LX72

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
528_K	531_D	6.431	1.00
52_I	56_L	5.087	1.00
27_F	49_I	4.592	1.00
454_F	458_S	4.241	1.00
500_A	551_T	4.237	1.00
264_V	268_W	4.114	1.00
415_Q	418_K	3.912	1.00
237_V	257_V	3.790	1.00
55_V	65_A	3.776	1.00
222_E	273_T	3.694	1.00
553_L	557_V	3.688	1.00
51_L	65_A	3.651	1.00
229_V	265_F	3.575	1.00
393_V	397_F	3.440	1.00
460_V	544_L	3.243	1.00
30_W	35_K	3.112	1.00
411_K	415_Q	3.084	1.00
327_K	331_T	3.079	1.00
96_K	412_E	2.955	1.00
97_T	401_I	2.917	1.00
124_S	258_S	2.906	1.00
111_T	116_L	2.897	1.00
162_I	213_I	2.851	1.00
544_L	548_C	2.828	1.00
180_V	480_G	2.757	1.00
27_F	31_A	2.732	1.00
51_L	433_V	2.728	1.00
492_M	497_S	2.677	1.00
317_M	390_I	2.667	1.00
47_L	69_A	2.652	1.00
73_A	425_A	2.632	1.00
92_K	416_E	2.608	1.00
215_S	219_K	2.603	1.00
53_I	57_V	2.547	1.00
197_R	243_N	2.530	1.00
20_A	57_V	2.404	1.00
395_S	399_T	2.352	1.00
37_M	41_T	2.314	1.00
96_K	405_D	2.312	1.00
549_I	553_L	2.253	1.00
404_K	408_T	2.222	1.00
299_Y	303_Q	2.204	1.00
396_K	406_W	2.166	1.00
407_G	411_K	2.161	1.00
233_S	261_A	2.151	1.00
545_L	549_I	2.151	1.00
391_A	395_S	2.135	1.00
236_V	240_L	2.135	1.00
177_I	195_V	2.083	0.99
302_G	306_K	2.081	0.99
309_S	398_I	2.050	0.99
48_G	52_I	2.048	0.99
460_V	548_C	2.046	0.99
194_M	495_V	2.031	0.99
484_K	498_V	2.031	0.99
329_A	332_G	1.998	0.99
402_S	405_D	1.998	0.99
147_V	523_V	1.995	0.99
197_R	239_Y	1.989	0.99
157_A	519_A	1.951	0.99
204_V	235_A	1.928	0.99
434_T	440_S	1.926	0.99
305_F	309_S	1.901	0.99
225_P	269_W	1.898	0.99
253_L	257_V	1.896	0.99
306_K	400_A	1.840	0.99
180_V	498_V	1.832	0.99
323_I	326_V	1.820	0.98
240_L	244_F	1.817	0.98
321_W	387_A	1.807	0.98
96_K	408_T	1.802	0.98
30_W	34_I	1.800	0.98
305_F	312_L	1.798	0.98
44_L	426_S	1.780	0.98
342_K	347_V	1.772	0.98
403_W	407_G	1.759	0.98
233_S	258_S	1.738	0.98
18_A	446_T	1.732	0.98
168_V	472_D	1.719	0.98
300_R	303_Q	1.711	0.98
480_G	498_V	1.694	0.98
90_L	392_A	1.677	0.97
31_A	37_M	1.675	0.97
233_S	257_V	1.673	0.97
473_T	508_G	1.667	0.97
211_I	223_I	1.659	0.97
340_F	377_K	1.657	0.97
116_L	226_A	1.651	0.97
326_V	329_A	1.649	0.97
81_G	421_I	1.649	0.97
101_D	104_R	1.641	0.97
241_S	253_L	1.635	0.97
122_A	210_L	1.631	0.97
260_A	264_V	1.613	0.97
70_T	347_V	1.605	0.97
208_L	227_I	1.595	0.97
195_V	503_S	1.581	0.96
169_A	195_V	1.574	0.96
509_K	515_S	1.571	0.96
187_P	190_E	1.559	0.96
205_F	208_L	1.552	0.96
181_E	186_I	1.551	0.96
463_W	540_S	1.548	0.96
178_T	247_P	1.541	0.96
325_S	329_A	1.537	0.96
45_A	48_G	1.534	0.96
106_S	308_W	1.531	0.96
196_G	242_S	1.522	0.95
38_K	42_A	1.521	0.95
118_A	159_I	1.515	0.95
239_Y	244_F	1.514	0.95
180_V	191_I	1.497	0.95
193_Q	243_N	1.473	0.95
303_Q	306_K	1.468	0.94
204_V	231_G	1.458	0.94
198_Q	554_Q	1.456	0.94
31_A	45_A	1.454	0.94
277_F	280_E	1.432	0.94
71_Q	436_S	1.431	0.94
198_Q	550_I	1.426	0.93
119_L	230_S	1.414	0.93
105_S	299_Y	1.412	0.93
226_A	265_F	1.400	0.93
472_D	505_G	1.391	0.93
20_A	23_V	1.372	0.92
92_K	413_T	1.369	0.92
165_T	510_M	1.364	0.92
224_W	227_I	1.364	0.92
265_F	269_W	1.358	0.92
129_L	137_A	1.354	0.92
181_E	188_A	1.351	0.92
114_R	277_F	1.348	0.91
137_A	530_S	1.330	0.91
147_V	525_L	1.321	0.91
390_I	394_L	1.316	0.90
42_A	128_F	1.315	0.90
90_L	314_L	1.309	0.90
179_A	182_G	1.291	0.90
158_G	535_F	1.291	0.90
552_F	556_H	1.289	0.89
198_Q	503_S	1.277	0.89
19_L	23_V	1.275	0.89
56_L	62_A	1.275	0.89
122_A	126_G	1.275	0.89
401_I	405_D	1.253	0.88
230_S	262_L	1.253	0.88
205_F	542_F	1.251	0.88
172_A	175_I	1.242	0.88
122_A	163_A	1.238	0.87
89_F	392_A	1.232	0.87
126_G	163_A	1.231	0.87
453_M	456_F	1.228	0.87
538_K	542_F	1.221	0.87
66_L	69_A	1.211	0.86
68_S	71_Q	1.201	0.86
95_V	101_D	1.201	0.86
467_F	536_T	1.198	0.86
154_L	312_L	1.198	0.86
122_A	195_V	1.194	0.85
516_I	533_F	1.194	0.85
480_G	484_K	1.193	0.85
237_V	254_S	1.179	0.85
239_Y	243_N	1.174	0.84
234_F	251_D	1.171	0.84
507_T	543_L	1.169	0.84
202_L	546_L	1.167	0.84
114_R	151_F	1.165	0.84
154_L	535_F	1.161	0.84
175_I	178_T	1.158	0.84
55_V	62_A	1.155	0.84
545_L	548_C	1.152	0.83
232_V	393_V	1.139	0.83
127_A	167_P	1.135	0.82
75_Y	432_Y	1.131	0.82
456_F	545_L	1.129	0.82
56_L	59_R	1.126	0.82
209_Y	539_H	1.123	0.82
520_C	532_L	1.118	0.81
199_L	238_Q	1.114	0.81
225_P	271_P	1.109	0.81
309_S	312_L	1.107	0.81
136_G	171_G	1.107	0.81
329_A	333_H	1.107	0.81
320_V	330_L	1.106	0.81
491_G	494_P	1.099	0.80
158_G	532_L	1.096	0.80
237_V	253_L	1.095	0.80
450_T	453_M	1.089	0.80
313_L	398_I	1.087	0.80
117_Q	149_L	1.082	0.79
409_V	412_E	1.079	0.79
265_F	268_W	1.076	0.79
229_V	261_A	1.073	0.79
46_T	430_F	1.072	0.79
215_S	220_A	1.070	0.78
51_L	55_V	1.069	0.78
317_M	391_A	1.067	0.78
201_F	550_I	1.065	0.78
23_V	49_I	1.064	0.78
92_K	412_E	1.061	0.78
276_R	280_E	1.061	0.78
135_F	471_S	1.060	0.78
118_A	214_M	1.057	0.78
184_T	498_V	1.053	0.77
511_I	537_I	1.053	0.77
112_D	274_T	1.052	0.77
186_I	495_V	1.049	0.77
36_R	531_D	1.046	0.77
83_I	175_I	1.044	0.77
428_V	482_L	1.041	0.77
83_I	172_A	1.039	0.76
169_A	472_D	1.035	0.76
73_A	429_G	1.032	0.76
119_L	262_L	1.032	0.76
208_L	224_W	1.030	0.76
67_M	70_T	1.026	0.75
97_T	173_I	1.023	0.75
78_L	388_I	1.014	0.75
116_L	223_I	1.014	0.75
121_I	142_S	1.013	0.75
196_G	243_N	1.009	0.74
44_L	422_L	1.009	0.74
240_L	546_L	1.005	0.74
372_I	436_S	1.001	0.74
538_K	541_L	1.001	0.74
74_V	376_Y	0.999	0.74
232_V	236_V	0.997	0.73
116_L	489_S	0.996	0.73
456_F	552_F	0.993	0.73
98_G	156_A	0.992	0.73
412_E	415_Q	0.991	0.73
441_T	485_V	0.990	0.73
212_I	220_A	0.989	0.73
392_A	406_W	0.988	0.73
322_G	382_G	0.987	0.73
27_F	46_T	0.987	0.73
481_N	484_K	0.982	0.72
326_V	330_L	0.979	0.72
86_T	410_F	0.977	0.72
339_V	456_F	0.977	0.72
190_E	495_V	0.977	0.72
97_T	399_T	0.975	0.72
69_A	433_V	0.975	0.72
119_L	227_I	0.974	0.72
89_F	406_W	0.971	0.71
320_V	326_V	0.970	0.71
81_G	424_I	0.966	0.71
380_V	383_S	0.961	0.71
47_L	133_A	0.960	0.70
179_A	443_L	0.959	0.70
404_K	545_L	0.959	0.70
117_Q	151_F	0.953	0.70
58_Y	442_T	0.952	0.70
531_D	534_R	0.948	0.70
82_W	386_T	0.935	0.68
455_T	548_C	0.933	0.68
55_V	260_A	0.932	0.68
446_T	449_L	0.932	0.68
434_T	439_M	0.930	0.68
487_A	510_M	0.929	0.68
179_A	477_L	0.927	0.68
93_I	409_V	0.927	0.68
169_A	506_V	0.924	0.68
416_E	420_P	0.923	0.67
16_L	57_V	0.920	0.67
215_S	221_L	0.919	0.67
225_P	265_F	0.917	0.67
204_V	232_V	0.911	0.66
102_I	299_Y	0.909	0.66
193_Q	239_Y	0.908	0.66
185_G	429_G	0.907	0.66
233_S	237_V	0.905	0.66
114_R	276_R	0.903	0.66
135_F	172_A	0.902	0.66
396_K	400_A	0.894	0.65
124_S	259_M	0.893	0.65
26_I	30_W	0.891	0.65
313_L	391_A	0.889	0.65
71_Q	432_Y	0.888	0.64
191_I	498_V	0.887	0.64
165_T	472_D	0.886	0.64
379_E	382_G	0.886	0.64
92_K	409_V	0.886	0.64
165_T	506_V	0.883	0.64
462_G	479_F	0.882	0.64
476_N	502_S	0.882	0.64
257_V	261_A	0.879	0.64
68_S	436_S	0.879	0.64
208_L	228_L	0.879	0.64
167_P	472_D	0.875	0.63
163_A	210_L	0.874	0.63
121_I	149_L	0.873	0.63
342_K	375_V	0.873	0.63
509_K	514_Q	0.873	0.63
327_K	330_L	0.871	0.63
309_S	313_L	0.871	0.63
53_I	58_Y	0.868	0.63
450_T	457_F	0.866	0.62
504_G	508_G	0.866	0.62
216_G	442_T	0.863	0.62
306_K	309_S	0.862	0.62
247_P	250_P	0.860	0.62
404_K	407_G	0.858	0.62
183_P	428_V	0.858	0.62
313_L	394_L	0.858	0.62
227_I	231_G	0.853	0.61
238_Q	472_D	0.852	0.61
435_N	474_S	0.852	0.61
200_P	239_Y	0.852	0.61
128_F	315_T	0.851	0.61
260_A	272_K	0.851	0.61
31_A	233_S	0.847	0.61
107_V	508_G	0.845	0.61
227_I	232_V	0.844	0.60
244_F	493_D	0.843	0.60
518_V	539_H	0.842	0.60
144_A	446_T	0.839	0.60
490_V	497_S	0.839	0.60
241_S	257_V	0.837	0.60
197_R	554_Q	0.835	0.60
66_L	549_I	0.834	0.60
55_V	332_G	0.834	0.60
293_N	305_F	0.834	0.60
445_M	489_S	0.832	0.59
247_P	262_L	0.830	0.59
129_L	141_I	0.830	0.59
444_G	485_V	0.827	0.59
257_V	326_V	0.827	0.59
37_M	45_A	0.820	0.58
330_L	340_F	0.814	0.58
17_S	57_V	0.812	0.57
45_A	481_N	0.811	0.57
461_L	482_L	0.808	0.57
167_P	195_V	0.807	0.57
166_A	251_D	0.805	0.57
85_V	414_V	0.805	0.57
395_S	401_I	0.804	0.57
146_L	213_I	0.804	0.57
19_L	292_T	0.802	0.57
275_F	278_A	0.798	0.56
168_V	510_M	0.797	0.56
460_V	541_L	0.797	0.56
541_L	545_L	0.792	0.56
410_F	414_V	0.791	0.55
48_G	342_K	0.791	0.55
49_I	52_I	0.790	0.55
192_S	423_T	0.787	0.55
52_I	59_R	0.785	0.55
31_A	311_F	0.783	0.55
298_A	549_I	0.782	0.55
179_A	468_I	0.781	0.55
180_V	477_L	0.781	0.55
80_I	135_F	0.781	0.55
248_E	322_G	0.780	0.54
465_G	475_A	0.780	0.54
314_L	386_T	0.780	0.54
46_T	88_V	0.780	0.54
127_A	163_A	0.780	0.54
69_A	429_G	0.775	0.54
324_P	329_A	0.775	0.54
200_P	235_A	0.774	0.54
151_F	455_T	0.774	0.54
278_A	293_N	0.774	0.54
233_S	511_I	0.772	0.54
135_F	473_T	0.771	0.54
128_F	516_I	0.770	0.53
158_G	536_T	0.769	0.53
297_P	301_G	0.768	0.53
339_V	380_V	0.766	0.53
225_P	268_W	0.766	0.53
296_A	528_K	0.765	0.53
28_F	145_L	0.764	0.53
132_A	172_A	0.764	0.53
110_I	154_L	0.763	0.53
191_I	484_K	0.763	0.53
230_S	233_S	0.762	0.53
177_I	191_I	0.760	0.53
339_V	381_L	0.760	0.53
56_L	293_N	0.758	0.52
463_W	544_L	0.757	0.52
549_I	557_V	0.756	0.52
188_A	192_S	0.754	0.52
318_I	388_I	0.752	0.52
509_K	518_V	0.751	0.52
174_G	246_G	0.750	0.52
118_A	457_F	0.749	0.51
418_K	422_L	0.748	0.51
232_V	237_V	0.748	0.51
546_L	550_I	0.747	0.51
26_I	339_V	0.747	0.51
518_V	530_S	0.745	0.51
102_I	303_Q	0.745	0.51
120_L	266_L	0.742	0.51
43_G	162_I	0.742	0.51
264_V	296_A	0.741	0.51
312_L	316_A	0.738	0.50
324_P	328_S	0.738	0.50
455_T	490_V	0.738	0.50
122_A	231_G	0.737	0.50
487_A	492_M	0.736	0.50
198_Q	201_F	0.736	0.50
192_S	247_P	0.735	0.50
294_P	297_P	0.734	0.50
295_A	316_A	0.734	0.50
225_P	229_V	0.734	0.50
163_A	167_P	0.734	0.50
62_A	268_W	0.732	0.50
339_V	344_L	0.731	0.50
276_R	279_G	0.730	0.50
423_T	505_G	0.729	0.50
121_I	125_F	0.728	0.49
189_M	192_S	0.727	0.49
221_L	263_A	0.727	0.49
76_G	423_T	0.724	0.49
66_L	488_L	0.724	0.49
67_M	343_W	0.723	0.49
328_S	332_G	0.723	0.49
82_W	385_G	0.723	0.49
472_D	503_S	0.721	0.49
447_L	450_T	0.721	0.49
190_E	194_M	0.720	0.49
510_M	525_L	0.719	0.49
199_L	203_S	0.715	0.48
177_I	476_N	0.715	0.48
195_V	393_V	0.714	0.48
501_N	509_K	0.714	0.48
114_R	275_F	0.712	0.48
218_R	273_T	0.710	0.48
68_S	460_V	0.709	0.48
130_E	171_G	0.708	0.48
62_A	339_V	0.707	0.47
86_T	388_I	0.707	0.47
36_R	42_A	0.706	0.47
156_A	308_W	0.706	0.47
88_V	105_S	0.706	0.47
123_F	254_S	0.706	0.47
32_L	36_R	0.704	0.47
345_N	373_E	0.704	0.47
397_F	403_W	0.703	0.47
25_I	131_G	0.703	0.47
28_F	46_T	0.703	0.47
318_I	321_W	0.702	0.47
48_G	332_G	0.702	0.47
266_L	269_W	0.702	0.47
52_I	63_E	0.702	0.47
128_F	247_P	0.700	0.47
537_I	542_F	0.697	0.46
169_A	238_Q	0.696	0.46
329_A	339_V	0.696	0.46
48_G	51_L	0.694	0.46
208_L	490_V	0.692	0.46
59_R	268_W	0.691	0.46
80_I	170_F	0.690	0.46
129_L	431_A	0.690	0.46
59_R	393_V	0.689	0.46
327_K	333_H	0.689	0.46
531_D	535_F	0.689	0.46
302_G	316_A	0.689	0.46
89_F	410_F	0.688	0.46
328_S	377_K	0.687	0.46
295_A	373_E	0.686	0.45
512_S	517_A	0.685	0.45
19_L	407_G	0.685	0.45
211_I	227_I	0.684	0.45
293_N	394_L	0.682	0.45
200_P	203_S	0.679	0.45
157_A	482_L	0.677	0.45
152_N	155_Y	0.675	0.44
267_K	298_A	0.674	0.44
88_V	137_A	0.673	0.44
239_Y	251_D	0.673	0.44
47_L	51_L	0.672	0.44
419_L	422_L	0.672	0.44
311_F	343_W	0.671	0.44
39_G	104_R	0.669	0.44
325_S	332_G	0.668	0.44
133_A	137_A	0.668	0.44
173_I	322_G	0.667	0.44
32_L	39_G	0.664	0.43
165_T	168_V	0.664	0.43
128_F	132_A	0.662	0.43
33_A	118_A	0.662	0.43
76_G	201_F	0.661	0.43
95_V	104_R	0.661	0.43
104_R	145_L	0.661	0.43
403_W	456_F	0.661	0.43
451_G	457_F	0.660	0.43
128_F	388_I	0.660	0.43
316_A	407_G	0.659	0.43
99_Q	304_I	0.659	0.43
215_S	519_A	0.659	0.43
20_A	53_I	0.659	0.43
137_A	473_T	0.658	0.43
110_I	265_F	0.658	0.43
422_L	426_S	0.658	0.43
26_I	341_L	0.658	0.43
154_L	389_L	0.657	0.43
70_T	313_L	0.655	0.42
415_Q	545_L	0.655	0.42
200_P	251_D	0.655	0.42
454_F	490_V	0.654	0.42
440_S	477_L	0.654	0.42
472_D	509_K	0.653	0.42
313_L	332_G	0.653	0.42
26_I	66_L	0.653	0.42
545_L	553_L	0.652	0.42
503_S	554_Q	0.652	0.42
431_A	513_P	0.652	0.42
169_A	177_I	0.652	0.42
402_S	488_L	0.651	0.42
122_A	507_T	0.650	0.42
238_Q	506_V	0.650	0.42
242_S	250_P	0.650	0.42
513_P	517_A	0.650	0.42
300_R	545_L	0.648	0.42
126_G	210_L	0.647	0.42
177_I	502_S	0.647	0.42
57_V	70_T	0.646	0.42
132_A	175_I	0.646	0.42
522_A	532_L	0.645	0.42
48_G	146_L	0.644	0.41
168_V	473_T	0.643	0.41
25_I	467_F	0.643	0.41
438_G	553_L	0.642	0.41
317_M	394_L	0.641	0.41
267_K	552_F	0.640	0.41
346_A	349_E	0.640	0.41
443_L	518_V	0.640	0.41
36_R	162_I	0.638	0.41
506_V	514_Q	0.638	0.41
325_S	328_S	0.638	0.41
78_L	263_A	0.637	0.41
254_S	313_L	0.637	0.41
36_R	95_V	0.635	0.41
61_P	224_W	0.635	0.41
56_L	294_P	0.635	0.41
196_G	238_Q	0.634	0.41
62_A	402_S	0.633	0.40
405_D	408_T	0.632	0.40
52_I	341_L	0.632	0.40
25_I	516_I	0.631	0.40
245_L	253_L	0.630	0.40
345_N	348_G	0.630	0.40
311_F	431_A	0.629	0.40
171_G	471_S	0.629	0.40
76_G	222_E	0.629	0.40
201_F	503_S	0.627	0.40
254_S	503_S	0.626	0.40
54_A	433_V	0.625	0.40
128_F	314_L	0.623	0.39
408_T	411_K	0.623	0.39
38_K	41_T	0.622	0.39
424_I	515_S	0.622	0.39
204_V	495_V	0.622	0.39
29_F	196_G	0.621	0.39
21_A	234_F	0.621	0.39
297_P	394_L	0.620	0.39
134_G	171_G	0.617	0.39
86_T	180_V	0.617	0.39
22_L	443_L	0.616	0.39
402_S	456_F	0.616	0.39
48_G	73_A	0.612	0.38
231_G	235_A	0.612	0.38
65_A	74_V	0.611	0.38
122_A	139_V	0.611	0.38
502_S	506_V	0.610	0.38
60_M	437_S	0.609	0.38
64_K	68_S	0.609	0.38
161_L	510_M	0.609	0.38
261_A	414_V	0.609	0.38
154_L	158_G	0.608	0.38
218_R	222_E	0.607	0.38
51_L	66_L	0.606	0.38
85_V	232_V	0.605	0.38
22_L	26_I	0.604	0.38
195_V	244_F	0.602	0.38
70_T	397_F	0.601	0.37
323_I	330_L	0.601	0.37
189_M	193_Q	0.601	0.37
130_E	136_G	0.600	0.37
278_A	292_T	0.600	0.37
218_R	398_I	0.600	0.37
117_Q	314_L	0.597	0.37
449_L	453_M	0.597	0.37
123_F	250_P	0.597	0.37
152_N	277_F	0.597	0.37
169_A	502_S	0.597	0.37
431_A	434_T	0.595	0.37
133_A	388_I	0.595	0.37
102_I	225_P	0.594	0.37
86_T	389_L	0.594	0.37
424_I	518_V	0.594	0.37
295_A	531_D	0.593	0.37
128_F	160_C	0.593	0.37
312_L	545_L	0.592	0.37
66_L	300_R	0.591	0.37
224_W	300_R	0.590	0.36
341_L	375_V	0.590	0.36
181_E	191_I	0.590	0.36
31_A	34_I	0.589	0.36
220_A	227_I	0.589	0.36
102_I	304_I	0.589	0.36
172_A	177_I	0.589	0.36
339_V	402_S	0.588	0.36
403_W	408_T	0.588	0.36
166_A	506_V	0.588	0.36
124_S	230_S	0.588	0.36
131_G	308_W	0.587	0.36
103_I	308_W	0.587	0.36
407_G	453_M	0.587	0.36
162_I	326_V	0.586	0.36
126_G	166_A	0.585	0.36
174_G	199_L	0.584	0.36
505_G	540_S	0.584	0.36
26_I	457_F	0.582	0.36
306_K	332_G	0.581	0.36
83_I	256_L	0.580	0.36
146_L	228_L	0.579	0.36
214_M	392_A	0.579	0.36
297_P	403_W	0.579	0.36
504_G	511_I	0.579	0.36
297_P	411_K	0.579	0.36
207_P	501_N	0.579	0.36
48_G	480_G	0.578	0.35
431_A	474_S	0.576	0.35
222_E	225_P	0.575	0.35
167_P	234_F	0.575	0.35
299_Y	304_I	0.574	0.35
294_P	400_A	0.573	0.35
23_V	53_I	0.573	0.35
20_A	177_I	0.571	0.35
83_I	90_L	0.571	0.35
80_I	179_A	0.571	0.35
443_L	468_I	0.570	0.35
26_I	273_T	0.568	0.35
450_T	532_L	0.566	0.34
245_L	550_I	0.563	0.34
407_G	415_Q	0.562	0.34
267_K	398_I	0.562	0.34
49_I	446_T	0.560	0.34
170_F	250_P	0.559	0.34
78_L	373_E	0.559	0.34
441_T	445_M	0.559	0.34
62_A	66_L	0.558	0.34
29_F	533_F	0.555	0.33
23_V	398_I	0.554	0.33
455_T	552_F	0.554	0.33
331_T	382_G	0.553	0.33
301_G	305_F	0.552	0.33
293_N	297_P	0.551	0.33
239_Y	550_I	0.551	0.33
164_N	514_Q	0.551	0.33
209_Y	491_G	0.550	0.33
248_E	384_A	0.550	0.33
36_R	101_D	0.550	0.33
474_S	477_L	0.550	0.33
55_V	66_L	0.549	0.33
199_L	472_D	0.549	0.33
456_F	459_P	0.548	0.33
55_V	418_K	0.548	0.33
194_M	496_L	0.547	0.33
280_E	292_T	0.546	0.33
518_V	523_V	0.546	0.33
118_A	122_A	0.546	0.33
85_V	89_F	0.546	0.33
298_A	394_L	0.545	0.33
346_A	374_A	0.544	0.32
490_V	552_F	0.544	0.32
97_T	461_L	0.544	0.32
50_A	433_V	0.543	0.32
63_E	398_I	0.543	0.32
111_T	475_A	0.542	0.32
454_F	536_T	0.542	0.32
348_G	373_E	0.540	0.32
21_A	493_D	0.540	0.32
15_L	305_F	0.540	0.32
45_A	49_I	0.540	0.32
423_T	444_G	0.538	0.32
104_R	504_G	0.538	0.32
19_L	294_P	0.538	0.32
137_A	176_P	0.538	0.32
86_T	175_I	0.538	0.32
135_F	171_G	0.538	0.32
295_A	402_S	0.536	0.32
91_Y	95_V	0.536	0.32
57_V	305_F	0.535	0.32
85_V	116_L	0.534	0.32
434_T	513_P	0.534	0.32
50_A	53_I	0.532	0.31
131_G	318_I	0.531	0.31
339_V	342_K	0.529	0.31
26_I	228_L	0.529	0.31
53_I	201_F	0.529	0.31
62_A	316_A	0.529	0.31
185_G	261_A	0.525	0.31
162_I	522_A	0.524	0.31
279_G	300_R	0.524	0.31
494_P	553_L	0.524	0.31
21_A	191_I	0.524	0.31
503_S	506_V	0.522	0.31
185_G	253_L	0.522	0.31
206_I	543_L	0.522	0.31
472_D	476_N	0.522	0.31
40_Y	419_L	0.521	0.31
33_A	530_S	0.520	0.30
272_K	297_P	0.519	0.30
15_L	278_A	0.519	0.30
295_A	403_W	0.519	0.30
347_V	375_V	0.519	0.30
58_Y	416_E	0.518	0.30
16_L	56_L	0.517	0.30
117_Q	420_P	0.517	0.30
250_P	254_S	0.517	0.30
110_I	248_E	0.517	0.30
314_L	430_F	0.516	0.30
237_V	241_S	0.515	0.30
76_G	85_V	0.514	0.30
484_K	488_L	0.514	0.30
43_G	427_V	0.513	0.30
144_A	534_R	0.512	0.30
88_V	388_I	0.512	0.30
501_N	514_Q	0.510	0.30
84_I	248_E	0.510	0.30
22_L	398_I	0.510	0.30
212_I	223_I	0.510	0.30
66_L	190_E	0.509	0.30
240_L	257_V	0.508	0.30
252_V	456_F	0.508	0.30
296_A	411_K	0.508	0.30
433_V	461_L	0.508	0.30
241_S	245_L	0.508	0.30
217_F	220_A	0.507	0.29
313_L	390_I	0.507	0.29
149_L	499_A	0.507	0.29
320_V	332_G	0.506	0.29
87_S	133_A	0.506	0.29
427_V	514_Q	0.506	0.29
39_G	424_I	0.506	0.29
59_R	549_I	0.506	0.29
62_A	408_T	0.505	0.29
29_F	53_I	0.505	0.29
292_T	295_A	0.504	0.29
178_T	182_G	0.504	0.29
93_I	401_I	0.504	0.29
183_P	229_V	0.504	0.29
427_V	512_S	0.503	0.29
103_I	467_F	0.503	0.29
127_A	164_N	0.503	0.29
69_A	487_A	0.502	0.29
29_F	531_D	0.502	0.29
459_P	513_P	0.502	0.29
88_V	311_F	0.502	0.29
312_L	333_H	0.501	0.29
445_M	482_L	0.501	0.29
44_L	403_W	0.501	0.29
52_I	292_T	0.500	0.29

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4r0cA	3	0.7922	99.8	0.877	Contact Map
4r1iA	2	0.8135	99.8	0.88	Contact Map
4f35D	2	0.7069	99.7	0.888	Contact Map
3qe7A	2	0.4458	10.6	0.983	Contact Map
3qnqA	2	0.4956	8.5	0.984	Contact Map
2m20A	2	0.0924	5	0.986	Contact Map
3d31C	2	0.3552	4.8	0.986	Contact Map
4oj2X	3	0.3464	4.4	0.986	Contact Map
1j4nA	4	0.3677	4.3	0.986	Contact Map
2m67A	1	0.1385	4.2	0.986	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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