EPSJ - BACSU - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

EPSJ - Uncharacterized glycosyltransferase EpsJ

UniProt:	P71059	Sequences: MIPLVSIIVPMYNVEPFIEECIDSLLRQTLSDIEIILVNDGTPDRSGEIAEDYAKRDARIRVIHQANGGLSSARNTGIKAARGTYIGFVDGDDYVSSAMFQRLTEEAEQNQLDIVGCGFYKQSSDRRTYVPPQLEANRVLTKPEMTEQLKHAHETRFIWYVWRYLYRRELFERANLLFDEDIRFAEDSPFNLSAFREAERVKMLDEGLYIYRENPNSLTEIPYKPAMDEHLQKQYQAKIAFYNHYGLAGACKEDLNVYICRHQLPMLLANACASPNSPKDIKKKIRQILSYDMVRQAVRHTPFQHEKLLRGERLVLALCKWRLTFLIKLFFEQRGTMKGSAKQA	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	344 (285)
Sequences:	11281 (10129)
Seq/√Len:	600.0

ECOLI - YIBD WCAA WCAE WBBL GTRB ARNC PGAC YAIP
BACSU - EPSJ CGED GGAA EPSH GGAB YFNE EPSE SPSA TUAG YWDF TAGF YKCC CSBB YKOT YDAM
HALSA - Q9HQP4 Q9HQP8 Q9HSC8 Q9HNK3 Q9HQQ6 Q9HQP3 Q9HR08 Q9HSB1
SULSO - Q7LXF7 Q97TZ0 Q97TY0 Q7LXG6 Q97X05 Q97YG5 Q97W52 Q97YN4 Q7LXY2 Q97WK7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
168_R	172_E	3.820	1.00
14_V	91_G	3.432	1.00
15_E	45_R	2.975	1.00
39_N	64_H	2.933	1.00
11_M	46_S	2.919	1.00
20_E	212_R	2.846	1.00
76_T	80_A	2.780	1.00
79_K	177_L	2.744	1.00
102_R	206_E	2.664	1.00
189_P	193_S	2.568	1.00
68_G	72_S	2.426	1.00
29_T	101_Q	2.313	1.00
47_G	64_H	2.296	1.00
112_L	202_K	2.258	1.00
51_E	64_H	2.246	1.00
45_R	48_E	2.203	1.00
19_E	23_D	2.174	1.00
96_S	210_I	2.162	1.00
6_S	83_G	2.149	1.00
47_G	51_E	2.144	1.00
72_S	180_E	2.121	1.00
63_I	80_A	2.100	1.00
37_L	50_A	2.083	1.00
5_V	104_T	2.066	1.00
19_E	52_D	2.063	1.00
87_G	100_F	2.053	1.00
13_N	43_P	2.025	1.00
47_G	62_V	1.967	1.00
106_E	202_K	1.934	1.00
120_Y	210_I	1.932	1.00
95_V	99_M	1.930	1.00
65_Q	68_G	1.924	1.00
34_E	61_R	1.919	1.00
8_I	77_G	1.911	1.00
23_D	53_Y	1.898	1.00
20_E	94_Y	1.874	1.00
113_D	167_R	1.864	1.00
85_Y	107_A	1.817	1.00
38_V	77_G	1.811	1.00
63_I	76_T	1.779	1.00
30_L	104_T	1.739	1.00
11_M	37_L	1.731	1.00
9_V	35_I	1.731	1.00
70_L	218_L	1.709	1.00
9_V	21_C	1.707	1.00
89_V	95_V	1.695	1.00
106_E	204_L	1.693	1.00
65_Q	76_T	1.687	1.00
5_V	100_F	1.663	1.00
4_L	84_T	1.647	1.00
94_Y	210_I	1.646	1.00
103_L	165_L	1.616	1.00
6_S	34_E	1.606	1.00
103_L	117_C	1.605	1.00
9_V	25_L	1.604	1.00
87_G	99_M	1.600	1.00
87_G	165_L	1.592	1.00
76_T	79_K	1.573	1.00
34_E	83_G	1.566	1.00
169_E	173_R	1.556	1.00
5_V	165_L	1.553	1.00
81_A	168_R	1.517	1.00
122_Q	210_I	1.513	1.00
98_A	102_R	1.512	1.00
74_R	90_D	1.497	1.00
12_Y	67_N	1.486	1.00
15_E	49_I	1.477	1.00
25_L	89_V	1.476	1.00
179_D	189_P	1.472	1.00
101_Q	105_E	1.468	1.00
22_I	53_Y	1.460	1.00
19_E	53_Y	1.458	1.00
35_I	60_I	1.453	1.00
61_R	80_A	1.451	1.00
94_Y	212_R	1.442	1.00
41_G	65_Q	1.436	1.00
65_Q	72_S	1.428	1.00
170_L	194_A	1.421	1.00
23_D	27_R	1.415	1.00
99_M	103_L	1.413	1.00
4_L	32_D	1.403	1.00
117_C	208_L	1.387	1.00
86_I	168_R	1.363	1.00
70_L	186_E	1.347	1.00
21_C	89_V	1.339	1.00
39_N	47_G	1.332	1.00
50_A	62_V	1.325	1.00
11_M	14_V	1.316	1.00
39_N	42_T	1.316	1.00
33_I	100_F	1.308	1.00
87_G	95_V	1.296	1.00
85_Y	165_L	1.289	1.00
106_E	110_N	1.289	1.00
19_E	49_I	1.286	1.00
171_F	190_F	1.282	1.00
78_I	86_I	1.280	1.00
52_D	56_R	1.279	1.00
120_Y	207_G	1.276	1.00
84_T	167_R	1.272	1.00
94_Y	122_Q	1.269	1.00
26_L	60_I	1.265	1.00
214_N	217_S	1.265	1.00
107_A	165_L	1.252	1.00
107_A	115_V	1.242	1.00
104_T	108_E	1.233	1.00
30_L	33_I	1.233	1.00
14_V	17_F	1.222	1.00
38_V	73_A	1.221	1.00
74_R	88_F	1.221	1.00
34_E	82_R	1.215	1.00
103_L	115_V	1.215	1.00
119_F	162_W	1.215	1.00
114_I	201_V	1.201	1.00
98_A	101_Q	1.194	1.00
61_R	82_R	1.193	1.00
40_D	67_N	1.184	1.00
13_N	42_T	1.176	1.00
78_I	88_F	1.174	1.00
48_E	51_E	1.172	1.00
27_R	97_S	1.167	1.00
106_E	109_Q	1.156	1.00
71_S	186_E	1.153	1.00
99_M	208_L	1.148	1.00
22_I	37_L	1.133	1.00
70_L	74_R	1.126	1.00
173_R	197_E	1.125	1.00
51_E	54_A	1.125	1.00
51_E	62_V	1.118	1.00
72_S	76_T	1.115	1.00
164_Y	191_N	1.113	1.00
99_M	117_C	1.109	1.00
102_R	105_E	1.103	1.00
11_M	50_A	1.101	1.00
68_G	73_A	1.082	1.00
22_I	35_I	1.077	1.00
110_N	202_K	1.074	1.00
170_L	198_A	1.073	1.00
54_A	62_V	1.070	1.00
78_I	171_F	1.066	1.00
118_G	203_M	1.066	1.00
114_I	194_A	1.050	1.00
6_S	36_I	1.037	1.00
166_Y	191_N	1.037	1.00
174_A	197_E	1.033	1.00
78_I	81_A	1.032	1.00
123_S	127_R	1.031	1.00
48_E	52_D	1.027	1.00
43_P	46_S	1.023	1.00
4_L	82_R	1.018	1.00
70_L	161_V	1.017	1.00
111_Q	200_R	1.003	1.00
161_V	178_F	1.003	1.00
22_I	26_L	1.000	1.00
5_V	87_G	0.999	1.00
4_L	83_G	0.994	1.00
81_A	86_I	0.994	1.00
217_S	220_E	0.987	1.00
105_E	109_Q	0.987	1.00
170_L	199_E	0.986	1.00
26_L	53_Y	0.986	1.00
11_M	18_I	0.984	1.00
102_R	208_L	0.983	1.00
7_I	33_I	0.967	1.00
106_E	115_V	0.965	1.00
25_L	95_V	0.963	1.00
74_R	186_E	0.963	1.00
169_E	172_E	0.961	1.00
40_D	73_A	0.957	1.00
40_D	69_G	0.956	1.00
89_V	209_Y	0.954	1.00
6_S	81_A	0.954	1.00
10_P	91_G	0.949	1.00
11_M	91_G	0.947	1.00
84_T	108_E	0.943	1.00
71_S	75_N	0.928	1.00
49_I	53_Y	0.924	1.00
113_D	199_E	0.919	1.00
47_G	50_A	0.918	1.00
7_I	25_L	0.916	1.00
190_F	194_A	0.909	1.00
23_D	26_L	0.907	1.00
96_S	120_Y	0.904	1.00
17_F	212_R	0.903	1.00
10_P	73_A	0.900	1.00
54_A	60_I	0.900	1.00
52_D	55_K	0.897	1.00
102_R	204_L	0.894	1.00
7_I	100_F	0.893	1.00
107_A	112_L	0.890	1.00
30_L	100_F	0.888	1.00
113_D	200_R	0.876	1.00
103_L	107_A	0.873	1.00
14_V	214_N	0.871	1.00
24_S	95_V	0.870	1.00
3_P	84_T	0.865	1.00
96_S	99_M	0.864	1.00
174_A	177_L	0.863	1.00
21_C	24_S	0.860	1.00
70_L	73_A	0.859	1.00
68_G	76_T	0.857	1.00
26_L	57_D	0.856	1.00
22_I	60_I	0.854	1.00
73_A	76_T	0.851	1.00
113_D	198_A	0.851	1.00
122_Q	212_R	0.849	1.00
78_I	177_L	0.848	1.00
18_I	50_A	0.832	1.00
29_T	98_A	0.822	1.00
40_D	68_G	0.822	1.00
116_G	164_Y	0.818	1.00
122_Q	126_R	0.816	1.00
174_A	194_A	0.814	1.00
166_Y	194_A	0.806	1.00
3_P	108_E	0.801	1.00
235_Y	239_I	0.800	1.00
45_R	49_I	0.798	1.00
88_F	178_F	0.797	1.00
161_V	164_Y	0.794	1.00
123_S	126_R	0.794	1.00
167_R	170_L	0.793	1.00
11_M	39_N	0.787	1.00
75_N	178_F	0.786	1.00
237_A	240_A	0.783	1.00
26_L	59_R	0.781	1.00
41_G	67_N	0.771	1.00
102_R	106_E	0.770	1.00
13_N	46_S	0.770	1.00
121_K	213_E	0.760	1.00
162_W	209_Y	0.759	1.00
23_D	56_R	0.758	1.00
196_R	241_F	0.756	1.00
233_K	236_Q	0.756	1.00
112_L	200_R	0.753	1.00
33_I	59_R	0.752	1.00
37_L	60_I	0.752	1.00
3_P	30_L	0.752	1.00
111_Q	167_R	0.752	1.00
213_E	220_E	0.751	1.00
233_K	237_A	0.747	1.00
96_S	208_L	0.746	1.00
170_L	174_A	0.745	1.00
75_N	177_L	0.744	1.00
166_Y	171_F	0.743	1.00
141_T	144_E	0.741	1.00
57_D	60_I	0.736	1.00
68_G	180_E	0.736	1.00
104_T	107_A	0.734	1.00
194_A	198_A	0.732	1.00
29_T	97_S	0.727	1.00
73_A	77_G	0.724	1.00
185_A	188_S	0.724	1.00
36_I	80_A	0.721	1.00
17_F	214_N	0.720	1.00
84_T	169_E	0.719	1.00
112_L	115_V	0.713	1.00
21_C	94_Y	0.713	1.00
25_L	35_I	0.713	1.00
153_H	156_R	0.712	1.00
3_P	32_D	0.707	1.00
21_C	25_L	0.701	1.00
115_V	165_L	0.701	1.00
26_L	35_I	0.696	1.00
198_A	201_V	0.695	1.00
240_A	244_H	0.691	1.00
18_I	46_S	0.688	1.00
118_G	205_D	0.685	1.00
86_I	171_F	0.685	1.00
104_T	165_L	0.682	1.00
36_I	81_A	0.682	1.00
241_F	245_Y	0.682	1.00
70_L	90_D	0.682	1.00
179_D	237_A	0.680	1.00
116_G	203_M	0.678	1.00
36_I	77_G	0.676	1.00
229_E	233_K	0.670	1.00
21_C	93_D	0.669	1.00
118_G	207_G	0.668	1.00
36_I	61_R	0.667	1.00
4_L	104_T	0.666	1.00
10_P	74_R	0.665	1.00
5_V	107_A	0.663	1.00
95_V	100_F	0.662	1.00
15_E	44_D	0.661	1.00
123_S	129_Y	0.660	1.00
237_A	241_F	0.660	1.00
230_H	233_K	0.659	1.00
232_Q	236_Q	0.659	1.00
240_A	243_N	0.658	1.00
24_S	94_Y	0.657	1.00
15_E	18_I	0.656	1.00
8_I	88_F	0.654	1.00
5_V	30_L	0.654	1.00
19_E	56_R	0.651	1.00
106_E	112_L	0.651	1.00
239_I	243_N	0.649	1.00
4_L	108_E	0.648	1.00
34_E	81_A	0.648	1.00
18_I	49_I	0.647	1.00
75_N	180_E	0.643	1.00
33_I	82_R	0.642	1.00
4_L	30_L	0.641	1.00
124_S	127_R	0.641	1.00
204_L	207_G	0.640	1.00
110_N	200_R	0.639	1.00
170_L	197_E	0.638	1.00
75_N	78_I	0.637	1.00
42_T	46_S	0.632	1.00
85_Y	167_R	0.631	1.00
18_I	91_G	0.629	1.00
22_I	50_A	0.629	1.00
14_V	70_L	0.626	1.00
41_G	66_A	0.623	1.00
10_P	40_D	0.622	1.00
50_A	54_A	0.622	1.00
189_P	237_A	0.621	1.00
234_Q	238_K	0.621	1.00
15_E	48_E	0.620	1.00
258_Y	261_R	0.620	1.00
26_L	33_I	0.619	1.00
95_V	209_Y	0.617	1.00
9_V	91_G	0.616	1.00
46_S	49_I	0.613	1.00
113_D	116_G	0.613	1.00
214_N	218_L	0.612	1.00
38_V	76_T	0.611	1.00
179_D	193_S	0.611	1.00
177_L	193_S	0.609	1.00
4_L	33_I	0.608	1.00
53_Y	57_D	0.608	1.00
49_I	52_D	0.608	1.00
230_H	234_Q	0.607	1.00
214_N	220_E	0.607	1.00
87_G	117_C	0.607	1.00
9_V	89_V	0.604	1.00
115_V	204_L	0.602	1.00
25_L	37_L	0.600	1.00
70_L	88_F	0.598	1.00
7_I	87_G	0.593	1.00
77_G	90_D	0.590	1.00
51_E	55_K	0.586	1.00
70_L	184_F	0.585	1.00
28_Q	101_Q	0.585	1.00
238_K	242_Y	0.584	1.00
159_W	188_S	0.583	1.00
116_G	159_W	0.582	1.00
160_Y	188_S	0.581	1.00
277_S	281_I	0.579	1.00
12_Y	40_D	0.579	1.00
126_R	129_Y	0.578	1.00
20_E	23_D	0.577	1.00
161_V	191_N	0.574	1.00
90_D	186_E	0.574	1.00
85_Y	108_E	0.571	1.00
214_N	219_T	0.569	1.00
3_P	83_G	0.569	1.00
8_I	38_V	0.568	1.00
85_Y	104_T	0.567	1.00
256_N	259_I	0.565	1.00
65_Q	73_A	0.563	1.00
9_V	37_L	0.563	1.00
21_C	91_G	0.561	1.00
114_I	164_Y	0.559	1.00
155_T	200_R	0.559	1.00
15_E	46_S	0.559	1.00
32_D	59_R	0.556	0.99
265_P	269_A	0.555	0.99
189_P	192_L	0.553	0.99
53_Y	56_R	0.552	0.99
21_C	95_V	0.552	0.99
87_G	103_L	0.551	0.99
204_L	208_L	0.551	0.99
154_E	157_F	0.549	0.99
98_A	206_E	0.547	0.99
172_E	177_L	0.545	0.99
124_S	215_P	0.545	0.99
135_E	138_R	0.543	0.99
255_L	259_I	0.542	0.99
173_R	199_E	0.542	0.99
103_L	204_L	0.542	0.99
242_Y	245_Y	0.540	0.99
223_Y	227_M	0.540	0.99
87_G	163_R	0.539	0.99
28_Q	100_F	0.538	0.99
13_N	44_D	0.537	0.99
75_N	79_K	0.537	0.99
274_S	278_P	0.537	0.99
235_Y	238_K	0.536	0.99
114_I	198_A	0.535	0.99
29_T	33_I	0.535	0.99
8_I	168_R	0.533	0.99
239_I	242_Y	0.533	0.99
159_W	164_Y	0.532	0.99
119_F	163_R	0.532	0.99
75_N	193_S	0.531	0.99
8_I	86_I	0.530	0.99
98_A	208_L	0.530	0.99
17_F	21_C	0.530	0.99
166_Y	190_F	0.528	0.99
226_A	230_H	0.528	0.99
174_A	190_F	0.527	0.99
9_V	22_I	0.526	0.99
89_V	99_M	0.526	0.99
54_A	57_D	0.524	0.99
47_G	54_A	0.523	0.99
236_Q	240_A	0.523	0.99
38_V	63_I	0.522	0.99
146_T	149_L	0.521	0.99
41_G	68_G	0.521	0.99
191_N	195_F	0.521	0.99
14_V	21_C	0.520	0.99
219_T	222_P	0.520	0.99
280_D	284_K	0.517	0.99
61_R	64_H	0.517	0.99
69_G	73_A	0.517	0.99
28_Q	95_V	0.516	0.99
105_E	108_E	0.515	0.99
266_M	270_N	0.513	0.99
161_V	186_E	0.511	0.99
45_R	52_D	0.511	0.99
74_R	178_F	0.506	0.99
284_K	287_Q	0.505	0.99
10_P	90_D	0.505	0.99
14_V	90_D	0.505	0.99
171_F	177_L	0.503	0.99
46_S	50_A	0.503	0.99
113_D	170_L	0.501	0.99
30_L	101_Q	0.500	0.99
88_F	171_F	0.500	0.99

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3bcvA	2	0.5407	100	0.311	Contact Map
3l7iA	4	0.0785	100	0.324	Contact Map
2z86A	2	0.7326	100	0.363	Contact Map
1qg8A	1	0.6424	100	0.373	Contact Map
1xhbA	1	0.9244	100	0.41	Contact Map
2d7iA	1	0.9709	100	0.413	Contact Map
5ajoA	1	0.9738	100	0.428	Contact Map
4fixA	3	0.9564	100	0.444	Contact Map
2nxvA	4	0.6628	100	0.482	Contact Map
3ckjA	2	0.7442	100	0.483	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0105 seconds.