EPSC - BACSU - GREMLIN Contacts

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EPSC - Probable polysaccharide biosynthesis protein EpsC

UniProt:	P71052	Sequences: MIIALDTYLVLNSVIAGYQFLKDSYQFYDSGALLLTAVSLLLSYHVCAFLFNQYKQVWTYTGLGELIVLLKGITLSAAVTGVIQYAVYHTMFFRLLTACWVLQLLSIGGTRILSRVLNESIRKKRCASSRALIIGAGSGGTLMVRQLLSKDEPDIIPVAFIDDDQTKHKLEIMGLPVIGGKESIMPAVQKLKINYIIIAIPSLRTHELQVLYKECVRTGVSIKIMPHFDEMLLGTRTAGQIRDVKAEDLLGRKPVTLDTSEISNRIKGKTVLVTGAGGSIGSEICRQISAFQPKEIILLGHGENSIHSIYTELNGRFGKHIVFHTEIADVQDRDKMFTLMKKYEPHVVYHAAAHKHVPLMEHNPEEAVKNNIIGTKNVAEAADMSGTETFVLISSDKAVNPANVMGATKRFAEMIIMNLGKVSRTKFVAVRFGNVLGSRGSVIPIFKKQIEKGGPVTVTHPAMTRYFMTIPEASRLVIQAGALAKGRQIFVLDMGEPVKIVDLAKNLIHLSGYTTEQVPIEFTGIRPGEKMYEELLNKNEVHAEQIFPKIHIGKAVDGDWPVLMRFIEDFHELPEADLRARLFAAINTSEEMTAASVH	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	598 (588)
Sequences:	2382 (1815)
Seq/√Len:	74.9

BACSU - EPSC

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
501_V	522_F	6.862	1.00
346_H	388_E	5.408	1.00
276_A	298_L	5.049	1.00
340_M	348_V	4.747	1.00
337_F	384_M	4.691	1.00
299_L	328_A	4.284	1.00
132_L	159_A	4.234	1.00
159_A	178_I	4.068	1.00
461_P	522_F	3.640	1.00
74_T	100_W	3.559	1.00
144_V	160_F	3.537	1.00
207_E	210_V	3.428	1.00
376_K	380_E	3.411	1.00
450_I	456_V	3.256	1.00
372_I	411_F	3.250	1.00
448_K	452_K	3.243	1.00
295_E	322_V	3.176	1.00
270_T	295_E	3.061	1.00
269_K	388_E	2.886	1.00
448_K	451_E	2.810	1.00
289_S	321_I	2.796	1.00
130_R	156_I	2.786	1.00
284_I	288_I	2.768	1.00
379_A	419_L	2.745	1.00
295_E	324_H	2.745	1.00
461_P	501_V	2.735	1.00
335_K	366_E	2.721	1.00
130_R	194_N	2.685	1.00
307_H	445_I	2.668	1.00
458_V	522_F	2.626	1.00
463_M	525_I	2.600	1.00
286_R	312_E	2.581	1.00
270_T	294_K	2.578	1.00
21_L	93_F	2.506	1.00
501_V	505_K	2.461	1.00
332_D	369_K	2.450	1.00
297_I	326_E	2.449	1.00
337_F	385_S	2.449	1.00
310_Y	314_N	2.448	1.00
333_R	380_E	2.368	1.00
578_L	581_R	2.325	1.00
274_T	378_V	2.322	1.00
360_M	367_A	2.318	1.00
383_D	423_S	2.266	1.00
299_L	336_M	2.247	1.00
428_V	484_A	2.231	1.00
464_T	532_Y	2.214	1.00
164_D	167_K	2.199	1.00
380_E	415_I	2.193	1.00
13_S	106_S	2.174	1.00
368_V	408_T	2.174	1.00
269_K	346_H	2.146	1.00
188_V	218_T	2.143	1.00
295_E	343_Y	2.135	1.00
368_V	582_L	2.116	1.00
140_G	160_F	2.080	1.00
348_V	382_A	2.053	1.00
21_L	92_F	2.040	1.00
21_L	94_R	2.036	1.00
311_T	445_I	2.029	1.00
326_E	339_L	2.022	1.00
456_V	508_I	2.015	1.00
188_V	220_V	2.009	1.00
147_L	157_P	2.007	1.00
200_I	203_L	2.004	1.00
389_T	426_K	1.999	1.00
134_I	161_I	1.999	1.00
44_Y	99_C	1.987	1.00
337_F	341_K	1.968	1.00
336_M	381_A	1.961	1.00
327_I	360_M	1.959	1.00
136_A	140_G	1.957	1.00
133_I	144_V	1.936	1.00
513_Y	517_Q	1.924	1.00
144_V	157_P	1.922	1.00
270_T	345_P	1.903	1.00
458_V	501_V	1.873	1.00
302_G	305_S	1.847	1.00
267_K	292_Q	1.841	1.00
273_V	285_C	1.826	1.00
505_K	515_T	1.819	1.00
198_I	208_L	1.811	1.00
195_Y	223_K	1.801	1.00
132_L	193_I	1.798	1.00
585_A	588_T	1.794	1.00
11_L	41_L	1.793	1.00
273_V	288_I	1.789	1.00
333_R	337_F	1.762	1.00
306_I	327_I	1.749	1.00
304_N	308_S	1.747	1.00
133_I	160_F	1.745	1.00
386_G	424_R	1.739	1.00
464_T	497_P	1.730	1.00
9_L	106_S	1.725	1.00
330_V	378_V	1.720	1.00
404_V	586_I	1.715	1.00
144_V	175_L	1.709	1.00
129_S	195_Y	1.703	1.00
336_M	377_N	1.703	1.00
373_I	567_I	1.700	1.00
411_F	586_I	1.687	1.00
379_A	427_F	1.686	1.00
263_S	267_K	1.685	1.00
279_S	470_I	1.673	1.00
285_C	296_I	1.668	1.00
265_R	481_G	1.657	1.00
569_D	585_A	1.653	1.00
315_G	452_K	1.652	1.00
333_R	377_N	1.642	1.00
268_G	294_K	1.641	1.00
335_K	338_T	1.628	1.00
400_N	534_E	1.606	0.99
101_V	105_L	1.605	0.99
559_D	562_V	1.597	0.99
277_G	305_S	1.593	0.99
258_D	261_E	1.583	0.99
381_A	385_S	1.577	0.99
379_A	415_I	1.577	0.99
272_L	348_V	1.576	0.99
272_L	299_L	1.562	0.99
270_T	346_H	1.562	0.99
299_L	339_L	1.561	0.99
7_T	41_L	1.552	0.99
307_H	311_T	1.547	0.99
52_N	55_K	1.534	0.99
391_V	428_V	1.529	0.99
340_M	385_S	1.525	0.99
300_G	305_S	1.513	0.99
502_D	505_K	1.508	0.99
403_N	463_M	1.507	0.99
300_G	306_I	1.505	0.99
77_A	100_W	1.490	0.99
183_S	186_P	1.479	0.99
309_I	312_E	1.470	0.99
289_S	317_F	1.463	0.99
499_K	502_D	1.462	0.99
178_I	187_A	1.460	0.99
335_K	365_E	1.453	0.99
5_L	9_L	1.453	0.99
223_K	243_D	1.450	0.99
7_T	45_H	1.445	0.99
221_S	243_D	1.444	0.99
328_A	336_M	1.443	0.99
129_S	194_N	1.434	0.99
573_L	585_A	1.429	0.99
188_V	193_I	1.427	0.99
198_I	212_Y	1.425	0.99
168_H	180_G	1.421	0.99
130_R	192_K	1.419	0.99
266_I	347_V	1.416	0.99
285_C	298_L	1.415	0.99
426_K	484_A	1.403	0.99
47_C	75_L	1.391	0.99
157_P	175_L	1.389	0.99
325_T	362_H	1.382	0.98
337_F	381_A	1.372	0.98
51_F	75_L	1.368	0.98
70_L	104_L	1.365	0.98
564_M	568_E	1.364	0.98
310_Y	362_H	1.358	0.98
315_G	445_I	1.354	0.98
566_F	589_S	1.353	0.98
10_V	103_Q	1.345	0.98
213_K	216_V	1.335	0.98
22_K	92_F	1.330	0.98
73_I	104_L	1.329	0.98
289_S	318_G	1.325	0.98
344_E	385_S	1.313	0.98
134_I	200_I	1.313	0.98
137_G	163_D	1.309	0.98
44_Y	76_S	1.309	0.98
133_I	199_A	1.307	0.98
130_R	158_V	1.293	0.98
566_F	588_T	1.288	0.98
67_I	71_K	1.284	0.97
20_F	102_L	1.283	0.97
241_I	513_Y	1.277	0.97
288_I	293_P	1.277	0.97
136_A	163_D	1.274	0.97
443_I	507_L	1.274	0.97
340_M	387_T	1.273	0.97
456_V	513_Y	1.271	0.97
208_L	224_I	1.270	0.97
378_V	390_F	1.270	0.97
466_Y	535_L	1.266	0.97
180_G	183_S	1.256	0.97
302_G	439_R	1.256	0.97
196_I	220_V	1.250	0.97
486_G	490_F	1.250	0.97
139_G	163_D	1.249	0.97
373_I	571_H	1.248	0.97
230_E	235_T	1.248	0.97
131_A	194_N	1.244	0.97
318_G	321_I	1.242	0.97
131_A	155_I	1.237	0.97
230_E	242_R	1.232	0.97
136_A	162_D	1.230	0.97
102_L	106_S	1.229	0.97
311_T	448_K	1.223	0.97
276_A	306_I	1.218	0.97
11_L	37_A	1.217	0.97
403_N	464_T	1.215	0.96
488_Q	552_I	1.212	0.96
393_I	477_V	1.211	0.96
285_C	313_L	1.206	0.96
204_R	207_E	1.201	0.96
382_A	387_T	1.199	0.96
584_A	588_T	1.198	0.96
186_P	190_K	1.194	0.96
537_N	542_H	1.189	0.96
161_I	184_I	1.185	0.96
133_I	147_L	1.184	0.96
203_L	207_E	1.183	0.96
270_T	297_I	1.182	0.96
51_F	72_G	1.179	0.96
195_Y	221_S	1.177	0.96
247_E	254_P	1.176	0.96
310_Y	325_T	1.175	0.96
141_T	173_M	1.164	0.96
411_F	589_S	1.152	0.95
454_G	518_V	1.152	0.95
139_G	225_M	1.151	0.95
418_N	560_W	1.151	0.95
3_I	45_H	1.145	0.95
161_I	187_A	1.143	0.95
196_I	215_C	1.142	0.95
450_I	518_V	1.136	0.95
328_A	335_K	1.132	0.95
246_A	507_L	1.131	0.95
257_L	474_S	1.127	0.95
458_V	523_T	1.122	0.95
265_R	347_V	1.119	0.94
336_M	378_V	1.116	0.94
132_L	187_A	1.116	0.94
254_P	475_R	1.114	0.94
262_I	291_F	1.114	0.94
330_V	374_G	1.111	0.94
302_G	306_I	1.105	0.94
338_T	342_K	1.101	0.94
283_E	287_Q	1.100	0.94
304_N	354_H	1.094	0.94
99_C	103_Q	1.094	0.94
137_G	200_I	1.092	0.94
265_R	349_Y	1.092	0.94
92_F	95_L	1.091	0.94
513_Y	518_V	1.088	0.94
196_I	218_T	1.080	0.93
389_T	428_V	1.078	0.93
395_S	408_T	1.077	0.93
298_L	306_I	1.073	0.93
298_L	313_L	1.069	0.93
447_K	451_E	1.068	0.93
300_G	439_R	1.067	0.93
407_A	411_F	1.066	0.93
17_G	95_L	1.064	0.93
335_K	339_L	1.063	0.93
310_Y	323_F	1.062	0.93
298_L	309_I	1.060	0.93
185_M	189_Q	1.057	0.93
383_D	427_F	1.055	0.92
331_Q	370_N	1.052	0.92
137_G	140_G	1.051	0.92
215_C	222_I	1.047	0.92
22_K	93_F	1.046	0.92
21_L	98_A	1.041	0.92
140_G	163_D	1.040	0.92
163_D	200_I	1.039	0.92
324_H	343_Y	1.037	0.92
483_L	547_F	1.035	0.92
328_A	339_L	1.034	0.92
5_L	110_T	1.033	0.92
224_I	242_R	1.030	0.92
392_L	429_A	1.028	0.92
158_V	193_I	1.027	0.91
326_E	335_K	1.024	0.91
155_I	195_Y	1.022	0.91
536_L	553_G	1.021	0.91
10_V	44_Y	1.021	0.91
76_S	99_C	1.013	0.91
18_Y	95_L	1.012	0.91
569_D	588_T	1.011	0.91
382_A	390_F	1.011	0.91
266_I	291_F	1.011	0.91
341_K	385_S	1.010	0.91
336_M	340_M	1.004	0.91
308_S	448_K	1.001	0.90
140_G	199_A	0.997	0.90
227_H	230_E	0.987	0.90
408_T	586_I	0.986	0.90
243_D	447_K	0.983	0.90
9_L	110_T	0.983	0.90
79_V	83_I	0.982	0.90
209_Q	496_E	0.979	0.89
543_A	554_K	0.979	0.89
402_A	532_Y	0.977	0.89
171_E	176_P	0.974	0.89
449_Q	454_G	0.971	0.89
244_V	511_S	0.970	0.89
273_V	296_I	0.970	0.89
144_V	173_M	0.967	0.89
369_K	574_P	0.964	0.89
379_A	425_T	0.963	0.89
150_K	154_D	0.963	0.89
114_S	118_N	0.955	0.88
43_S	79_V	0.952	0.88
458_V	520_I	0.951	0.88
515_T	519_P	0.950	0.88
309_I	325_T	0.950	0.88
333_R	384_M	0.949	0.88
73_I	103_Q	0.949	0.88
17_G	21_L	0.947	0.88
583_F	593_T	0.943	0.88
37_A	41_L	0.942	0.87
203_L	208_L	0.940	0.87
403_N	525_I	0.939	0.87
428_V	480_A	0.937	0.87
137_G	162_D	0.937	0.87
183_S	187_A	0.937	0.87
365_E	582_L	0.935	0.87
305_S	439_R	0.931	0.87
47_C	79_V	0.930	0.87
571_H	575_E	0.926	0.87
141_T	145_R	0.923	0.86
277_G	300_G	0.922	0.86
383_D	422_V	0.922	0.86
162_D	167_K	0.921	0.86
162_D	200_I	0.920	0.86
132_L	161_I	0.920	0.86
159_A	193_I	0.919	0.86
85_Y	93_F	0.918	0.86
300_G	463_M	0.918	0.86
9_L	13_S	0.917	0.86
185_M	214_E	0.915	0.86
368_V	372_I	0.914	0.86
297_I	343_Y	0.914	0.86
41_L	45_H	0.910	0.86
349_Y	481_G	0.910	0.86
380_E	419_L	0.910	0.86
40_L	80_T	0.909	0.86
447_K	511_S	0.909	0.86
134_I	196_I	0.908	0.86
505_K	509_H	0.906	0.85
140_G	200_I	0.905	0.85
430_V	492_L	0.905	0.85
391_V	484_A	0.903	0.85
445_I	448_K	0.892	0.84
400_N	537_N	0.887	0.84
132_L	184_I	0.886	0.84
516_E	519_P	0.886	0.84
131_A	195_Y	0.882	0.84
139_G	202_S	0.880	0.84
209_Q	213_K	0.878	0.84
411_F	415_I	0.877	0.83
163_D	167_K	0.876	0.83
489_I	552_I	0.873	0.83
354_H	429_A	0.872	0.83
360_M	405_M	0.871	0.83
21_L	95_L	0.866	0.83
148_L	157_P	0.865	0.83
143_M	241_I	0.865	0.83
301_H	305_S	0.864	0.83
358_P	526_R	0.863	0.82
61_T	114_S	0.863	0.82
509_H	515_T	0.863	0.82
340_M	378_V	0.862	0.82
19_Q	24_S	0.862	0.82
137_G	167_K	0.861	0.82
392_L	412_A	0.860	0.82
537_N	555_A	0.859	0.82
214_E	217_R	0.858	0.82
141_T	160_F	0.858	0.82
373_I	570_F	0.857	0.82
134_I	184_I	0.857	0.82
198_I	224_I	0.856	0.82
581_R	584_A	0.849	0.81
265_R	389_T	0.847	0.81
569_D	573_L	0.847	0.81
329_D	439_R	0.845	0.81
53_Q	69_L	0.843	0.81
415_I	419_L	0.841	0.81
332_D	366_E	0.840	0.81
304_N	439_R	0.840	0.81
536_L	542_H	0.839	0.81
100_W	104_L	0.839	0.81
44_Y	103_Q	0.838	0.81
38_V	42_L	0.837	0.81
266_I	349_Y	0.837	0.81
563_L	570_F	0.836	0.80
327_I	354_H	0.836	0.80
272_L	340_M	0.832	0.80
570_F	589_S	0.831	0.80
266_I	288_I	0.828	0.80
388_E	424_R	0.826	0.80
48_A	107_I	0.825	0.80
376_K	415_I	0.823	0.79
335_K	363_N	0.823	0.79
234_G	238_A	0.823	0.79
330_V	392_L	0.821	0.79
363_N	370_N	0.821	0.79
302_G	329_D	0.820	0.79
128_S	156_I	0.818	0.79
372_I	570_F	0.818	0.79
14_V	99_C	0.817	0.79
187_A	191_L	0.812	0.78
225_M	231_M	0.804	0.78
42_L	46_V	0.803	0.78
61_T	118_N	0.802	0.78
58_W	134_I	0.799	0.77
184_I	196_I	0.797	0.77
140_G	157_P	0.795	0.77
226_P	234_G	0.795	0.77
137_G	199_A	0.792	0.77
330_V	395_S	0.787	0.76
246_A	503_L	0.787	0.76
381_A	384_M	0.785	0.76
193_I	196_I	0.785	0.76
77_A	81_G	0.785	0.76
208_L	212_Y	0.784	0.76
317_F	321_I	0.783	0.76
312_E	469_T	0.778	0.75
365_E	574_P	0.777	0.75
331_Q	369_K	0.776	0.75
273_V	298_L	0.775	0.75
26_Q	30_S	0.773	0.75
348_V	378_V	0.773	0.75
416_I	429_A	0.769	0.75
245_K	447_K	0.768	0.74
163_D	207_E	0.768	0.74
383_D	419_L	0.767	0.74
485_K	552_I	0.767	0.74
160_F	178_I	0.763	0.74
349_Y	478_I	0.762	0.74
14_V	37_A	0.762	0.74
477_V	536_L	0.761	0.74
334_D	577_D	0.761	0.74
62_G	145_R	0.760	0.74
532_Y	536_L	0.759	0.74
411_F	567_I	0.758	0.74
300_G	354_H	0.755	0.73
312_E	316_R	0.755	0.73
404_V	583_F	0.755	0.73
22_K	94_R	0.754	0.73
568_E	571_H	0.754	0.73
436_L	503_L	0.754	0.73
48_A	53_Q	0.753	0.73
136_A	200_I	0.750	0.73
18_Y	21_L	0.750	0.73
277_G	309_I	0.749	0.73
265_R	482_A	0.749	0.73
326_E	343_Y	0.746	0.72
206_H	210_V	0.745	0.72
563_L	589_S	0.745	0.72
506_N	509_H	0.744	0.72
402_A	534_E	0.744	0.72
76_S	80_T	0.743	0.72
257_L	262_I	0.743	0.72
443_I	503_L	0.743	0.72
368_V	570_F	0.742	0.72
296_I	321_I	0.741	0.72
242_R	245_K	0.740	0.72
509_H	514_T	0.739	0.72
347_V	481_G	0.739	0.72
271_V	288_I	0.739	0.72
297_I	339_L	0.739	0.72
75_L	78_A	0.735	0.71
105_L	109_G	0.734	0.71
300_G	329_D	0.733	0.71
306_I	360_M	0.732	0.71
6_D	54_Y	0.732	0.71
538_K	541_V	0.730	0.71
418_N	421_K	0.728	0.70
59_T	118_N	0.728	0.70
340_M	381_A	0.726	0.70
268_G	320_H	0.725	0.70
418_N	422_V	0.725	0.70
139_G	162_D	0.724	0.70
447_K	507_L	0.724	0.70
256_T	260_S	0.722	0.70
56_Q	488_Q	0.721	0.70
140_G	167_K	0.718	0.69
22_K	30_S	0.716	0.69
392_L	415_I	0.716	0.69
336_M	339_L	0.714	0.69
463_M	532_Y	0.713	0.69
292_Q	320_H	0.711	0.69
304_N	360_M	0.709	0.68
251_G	284_I	0.708	0.68
260_S	264_N	0.708	0.68
66_L	108_G	0.708	0.68
306_I	354_H	0.708	0.68
415_I	567_I	0.706	0.68
360_M	439_R	0.705	0.68
40_L	376_K	0.704	0.68
378_V	387_T	0.702	0.68
215_C	218_T	0.701	0.68
255_V	474_S	0.700	0.67
354_H	370_N	0.700	0.67
502_D	522_F	0.699	0.67
98_A	102_L	0.699	0.67
17_G	98_A	0.699	0.67
58_W	61_T	0.698	0.67
94_R	98_A	0.698	0.67
132_L	178_I	0.697	0.67
305_S	309_I	0.697	0.67
140_G	162_D	0.696	0.67
562_V	588_T	0.694	0.67
139_G	167_K	0.693	0.67
437_G	447_K	0.692	0.67
136_A	167_K	0.692	0.67
231_M	236_R	0.687	0.66
56_Q	65_E	0.685	0.66
159_A	187_A	0.685	0.66
18_Y	91_M	0.684	0.66
184_I	215_C	0.683	0.66
107_I	110_T	0.680	0.65
257_L	261_E	0.678	0.65
63_L	387_T	0.676	0.65
420_G	486_G	0.676	0.65
583_F	591_E	0.674	0.65
306_I	439_R	0.671	0.64
22_K	27_F	0.670	0.64
421_K	557_D	0.670	0.64
565_R	568_E	0.670	0.64
242_R	349_Y	0.669	0.64
209_Q	506_N	0.669	0.64
579_R	582_L	0.667	0.64
314_N	323_F	0.667	0.64
134_I	178_I	0.666	0.64
282_S	309_I	0.666	0.64
573_L	581_R	0.666	0.64
93_F	98_A	0.666	0.64
329_D	370_N	0.666	0.64
436_L	491_V	0.665	0.64
306_I	325_T	0.664	0.63
147_L	197_I	0.663	0.63
483_L	546_I	0.663	0.63
139_G	199_A	0.663	0.63
334_D	337_F	0.661	0.63
306_I	359_L	0.660	0.63
115_R	118_N	0.660	0.63
462_A	499_K	0.659	0.63
569_D	581_R	0.659	0.63
200_I	208_L	0.658	0.63
23_D	94_R	0.658	0.63
243_D	451_E	0.658	0.63
547_F	550_I	0.657	0.63
366_E	369_K	0.656	0.62
307_H	359_L	0.656	0.62
255_V	492_L	0.656	0.62
331_Q	366_E	0.656	0.62
185_M	188_V	0.656	0.62
400_N	592_M	0.654	0.62
530_K	534_E	0.653	0.62
139_G	200_I	0.653	0.62
315_G	448_K	0.652	0.62
17_G	92_F	0.652	0.62
327_I	359_L	0.652	0.62
165_Q	341_K	0.651	0.62
61_T	108_G	0.651	0.62
378_V	427_F	0.651	0.62
116_V	147_L	0.649	0.62
301_H	329_D	0.647	0.61
69_L	73_I	0.647	0.61
331_Q	377_N	0.646	0.61
562_V	566_F	0.645	0.61
244_V	253_K	0.643	0.61
300_G	325_T	0.641	0.61
405_M	534_E	0.640	0.61
561_P	564_M	0.639	0.60
383_D	386_G	0.639	0.60
17_G	99_C	0.638	0.60
499_K	532_Y	0.637	0.60
3_I	7_T	0.637	0.60
302_G	354_H	0.634	0.60
286_R	309_I	0.632	0.60
51_F	71_K	0.632	0.60
185_M	217_R	0.632	0.60
354_H	403_N	0.631	0.59
251_G	506_N	0.630	0.59
481_G	511_S	0.629	0.59
10_V	107_I	0.628	0.59
227_H	236_R	0.628	0.59
255_V	547_F	0.627	0.59
400_N	532_Y	0.626	0.59
503_L	507_L	0.626	0.59
284_I	523_T	0.626	0.59
162_D	199_A	0.625	0.59
302_G	363_N	0.623	0.59
122_R	348_V	0.622	0.58
424_R	485_K	0.622	0.58
439_R	463_M	0.621	0.58
37_A	263_S	0.619	0.58
370_N	430_V	0.617	0.58
460_H	521_E	0.617	0.58
300_G	327_I	0.615	0.58
285_C	323_F	0.615	0.58
297_I	325_T	0.614	0.57
79_V	98_A	0.613	0.57
307_H	405_M	0.613	0.57
418_N	563_L	0.613	0.57
56_Q	114_S	0.611	0.57
422_V	560_W	0.610	0.57
78_A	82_V	0.610	0.57
48_A	72_G	0.609	0.57
58_W	146_Q	0.609	0.57
326_E	363_N	0.608	0.57
330_V	553_G	0.608	0.57
458_V	474_S	0.606	0.56
395_S	498_V	0.605	0.56
306_I	463_M	0.605	0.56
382_A	419_L	0.605	0.56
155_I	223_K	0.605	0.56
19_Q	25_Y	0.604	0.56
302_G	415_I	0.604	0.56
425_T	486_G	0.604	0.56
139_G	144_V	0.604	0.56
565_R	569_D	0.604	0.56
308_S	439_R	0.604	0.56
261_E	483_L	0.602	0.56
253_K	256_T	0.602	0.56
458_V	461_P	0.602	0.56
12_N	16_A	0.602	0.56
566_F	585_A	0.602	0.56
481_G	487_R	0.601	0.56
273_V	507_L	0.601	0.56
168_H	183_S	0.600	0.56
463_M	537_N	0.600	0.56
188_V	196_I	0.599	0.56
83_I	87_V	0.599	0.56
22_K	95_L	0.599	0.56
419_L	560_W	0.599	0.56
58_W	114_S	0.599	0.56
313_L	323_F	0.598	0.55
57_V	177_V	0.598	0.55
242_R	285_C	0.598	0.55
334_D	338_T	0.598	0.55
479_Q	483_L	0.598	0.55
166_T	177_V	0.597	0.55
363_N	477_V	0.597	0.55
508_I	513_Y	0.597	0.55
162_D	201_P	0.597	0.55
110_T	113_L	0.596	0.55
47_C	72_G	0.596	0.55
136_A	160_F	0.595	0.55
197_I	241_I	0.595	0.55
392_L	464_T	0.594	0.55
306_I	329_D	0.594	0.55
23_D	93_F	0.594	0.55
230_E	233_L	0.593	0.55
380_E	383_D	0.592	0.55
62_G	108_G	0.591	0.55
247_E	447_K	0.591	0.55
379_A	416_I	0.590	0.54
333_R	336_M	0.590	0.54
326_E	452_K	0.589	0.54
133_I	143_M	0.589	0.54
309_I	593_T	0.589	0.54
137_G	202_S	0.589	0.54
381_A	430_V	0.586	0.54
288_I	349_Y	0.586	0.54
483_L	486_G	0.585	0.54
172_I	177_V	0.584	0.54
225_M	296_I	0.584	0.54
8_Y	124_K	0.582	0.53
312_E	417_M	0.582	0.53
142_L	220_V	0.581	0.53
163_D	202_S	0.580	0.53
336_M	348_V	0.579	0.53
347_V	474_S	0.579	0.53
537_N	541_V	0.578	0.53
566_F	569_D	0.578	0.53
77_A	99_C	0.578	0.53
414_M	553_G	0.577	0.53
203_L	211_L	0.576	0.53
418_N	513_Y	0.574	0.52
580_A	584_A	0.574	0.52
265_R	478_I	0.573	0.52
18_Y	22_K	0.573	0.52
311_T	315_G	0.572	0.52
96_L	100_W	0.572	0.52
39_S	42_L	0.571	0.52
416_I	556_V	0.571	0.52
118_N	177_V	0.570	0.52
132_L	176_P	0.570	0.52
47_C	51_F	0.569	0.52
286_R	471_P	0.569	0.52
569_D	572_E	0.568	0.52
133_I	140_G	0.568	0.52
61_T	65_E	0.568	0.52
193_I	240_Q	0.568	0.52
179_G	182_E	0.567	0.52
73_I	107_I	0.565	0.51
116_V	177_V	0.564	0.51
63_L	116_V	0.564	0.51
307_H	444_P	0.563	0.51
25_Y	393_I	0.562	0.51
53_Q	231_M	0.560	0.51
246_A	349_Y	0.559	0.51
301_H	309_I	0.558	0.50
348_V	415_I	0.558	0.50
221_S	244_V	0.558	0.50
360_M	400_N	0.558	0.50
143_M	231_M	0.557	0.50
469_T	474_S	0.557	0.50
407_A	443_I	0.556	0.50
216_V	506_N	0.555	0.50
23_D	26_Q	0.555	0.50
289_S	322_V	0.555	0.50
14_V	36_T	0.555	0.50
250_L	436_L	0.555	0.50
535_L	551_H	0.554	0.50
91_M	96_L	0.554	0.50
62_G	115_R	0.554	0.50
372_I	415_I	0.554	0.50
246_A	469_T	0.553	0.50
272_L	464_T	0.552	0.50
151_D	154_D	0.552	0.50
161_I	185_M	0.552	0.50
456_V	501_V	0.552	0.50
254_P	460_H	0.551	0.50
402_A	553_G	0.551	0.50
63_L	115_R	0.550	0.49
215_C	331_Q	0.550	0.49
78_A	448_K	0.550	0.49
104_L	109_G	0.549	0.49
261_E	347_V	0.549	0.49
466_Y	497_P	0.549	0.49
134_I	185_M	0.549	0.49
572_E	576_A	0.549	0.49
136_A	139_G	0.549	0.49
543_A	562_V	0.548	0.49
378_V	553_G	0.548	0.49
9_L	458_V	0.547	0.49
402_A	530_K	0.547	0.49
244_V	510_L	0.547	0.49
140_G	481_G	0.547	0.49
262_I	479_Q	0.546	0.49
245_K	451_E	0.546	0.49
108_G	115_R	0.546	0.49
19_Q	241_I	0.545	0.49
73_I	100_W	0.545	0.49
587_N	591_E	0.544	0.49
277_G	298_L	0.544	0.49
189_Q	572_E	0.543	0.49
271_V	296_I	0.543	0.49
315_G	318_G	0.543	0.49
85_Y	89_H	0.543	0.49
141_T	484_A	0.543	0.49
77_A	96_L	0.542	0.48
9_L	12_N	0.542	0.48
101_V	129_S	0.542	0.48
139_G	201_P	0.542	0.48
376_K	571_H	0.541	0.48
87_V	499_K	0.541	0.48
379_A	382_A	0.541	0.48
294_K	572_E	0.540	0.48
344_E	386_G	0.540	0.48
284_I	477_V	0.539	0.48
300_G	525_I	0.538	0.48
537_N	592_M	0.538	0.48
254_P	450_I	0.538	0.48
265_R	269_K	0.537	0.48
491_V	542_H	0.537	0.48
271_V	543_A	0.537	0.48
327_I	408_T	0.537	0.48
175_L	178_I	0.536	0.48
134_I	187_A	0.536	0.48
24_S	94_R	0.536	0.48
383_D	424_R	0.535	0.48
261_E	299_L	0.535	0.48
321_I	417_M	0.535	0.48
34_L	38_V	0.534	0.47
143_M	201_P	0.533	0.47
73_I	97_T	0.533	0.47
68_V	72_G	0.533	0.47
399_V	405_M	0.532	0.47
134_I	179_G	0.531	0.47
106_S	113_L	0.531	0.47
69_L	108_G	0.531	0.47
148_L	175_L	0.531	0.47
464_T	536_L	0.530	0.47
344_E	424_R	0.530	0.47
311_T	314_N	0.530	0.47
318_G	322_V	0.530	0.47
484_A	487_R	0.529	0.47
49_F	297_I	0.529	0.47
570_F	573_L	0.528	0.47
354_H	592_M	0.527	0.47
282_S	471_P	0.527	0.47
43_S	76_S	0.527	0.47
540_E	553_G	0.527	0.47
322_V	359_L	0.527	0.47
49_F	55_K	0.527	0.47
304_N	307_H	0.526	0.46
403_N	407_A	0.526	0.46
26_Q	29_D	0.525	0.46
570_F	585_A	0.525	0.46
463_M	523_T	0.525	0.46
540_E	555_A	0.525	0.46
20_F	101_V	0.524	0.46
379_A	412_A	0.524	0.46
179_G	183_S	0.523	0.46
208_L	477_V	0.523	0.46
13_S	29_D	0.523	0.46
331_Q	363_N	0.522	0.46
273_V	527_P	0.522	0.46
437_G	463_M	0.521	0.46
267_K	568_E	0.520	0.46
228_F	273_V	0.520	0.46
331_Q	365_E	0.520	0.46
349_Y	551_H	0.518	0.45
326_E	362_H	0.518	0.45
297_I	456_V	0.518	0.45
188_V	215_C	0.517	0.45
72_G	170_L	0.517	0.45
222_I	477_V	0.517	0.45
46_V	50_L	0.517	0.45
392_L	430_V	0.517	0.45
458_V	508_I	0.516	0.45
165_Q	182_E	0.516	0.45
393_I	416_I	0.516	0.45
302_G	307_H	0.516	0.45
168_H	225_M	0.516	0.45
429_A	447_K	0.515	0.45
261_E	482_A	0.515	0.45
175_L	567_I	0.515	0.45
124_K	422_V	0.515	0.45
333_R	579_R	0.514	0.45
415_I	429_A	0.514	0.45
376_K	419_L	0.514	0.45
327_I	400_N	0.514	0.45
255_V	430_V	0.514	0.45
165_Q	268_G	0.513	0.45
333_R	381_A	0.513	0.45
224_I	241_I	0.513	0.45
237_T	344_E	0.513	0.45
13_S	16_A	0.513	0.45
284_I	392_L	0.513	0.45
66_L	456_V	0.513	0.45
230_E	240_Q	0.513	0.45
4_A	8_Y	0.512	0.45
349_Y	390_F	0.512	0.45
403_N	590_E	0.512	0.45
560_W	564_M	0.511	0.45
129_S	221_S	0.511	0.45
452_K	565_R	0.511	0.45
307_H	358_P	0.511	0.45
477_V	498_V	0.511	0.45
234_G	237_T	0.510	0.44
508_I	512_G	0.510	0.44
349_Y	403_N	0.510	0.44
272_L	347_V	0.509	0.44
300_G	304_N	0.509	0.44
415_I	489_I	0.508	0.44
567_I	574_P	0.508	0.44
4_A	7_T	0.508	0.44
43_S	47_C	0.508	0.44
75_L	79_V	0.507	0.44
205_T	251_G	0.507	0.44
182_E	514_T	0.507	0.44
43_S	214_E	0.506	0.44
172_I	175_L	0.505	0.44
335_K	491_V	0.505	0.44
439_R	536_L	0.505	0.44
536_L	552_I	0.505	0.44
16_A	97_T	0.504	0.44
478_I	483_L	0.504	0.44
129_S	154_D	0.504	0.44
137_G	201_P	0.503	0.44
327_I	513_Y	0.503	0.44
231_M	238_A	0.503	0.44
27_F	92_F	0.502	0.43
587_N	592_M	0.502	0.43
90_T	93_F	0.502	0.43
430_V	479_Q	0.502	0.43
251_G	392_L	0.502	0.43
302_G	308_S	0.501	0.43
42_L	182_E	0.501	0.43
277_G	492_L	0.501	0.43
198_I	215_C	0.501	0.43
159_A	284_I	0.500	0.43
417_M	555_A	0.500	0.43

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3pvzA	2	0.5736	100	0.65	Contact Map
4j2oA	5	0.5217	100	0.773	Contact Map
4g5hA	3	0.5535	100	0.778	Contact Map
2gn4A	5	0.5251	100	0.798	Contact Map
4tqgA	1	0.4849	100	0.813	Contact Map
4wkgA	5	0.7191	100	0.816	Contact Map
3st7A	2	0.4916	100	0.844	Contact Map
1rkxA	3	0.5184	100	0.849	Contact Map
1sb8A	2	0.5201	100	0.851	Contact Map
3rufA	2	0.5134	100	0.851	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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