BETB - BACSU - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

BETB - Betaine aldehyde dehydrogenase

UniProt:	P71016	Sequences: MSQTLFIDGEWISAEKEQIRSIINPFNQEEIATVSEGGREDAIKAIAAARRAFDKGEWSSLSGLERGKIVLKIAELIRRDLEELAELESLDTGKTLEESKADMDDIANVFQYYAGLADKDGGEIISSPIPDSESKIIREPIGVCGQITPWNYPLLQASWKIAPALAAGNTIVMKPSEITPLTTIKVFKLMEEAGVPKGVANLVLGPGATVGDELAVNKDVDLISFTGGIETGKKIMRAASGNVKKIALELGGKNPNIVFKDADLEVAVDQALNAVFFHAGQVCSAGSRLLVEDAIHDQFLAELVKRAKRIKLGNGFHAETESGPLISAEHRAKVEKYVEIGIEEGAKLETGGKRPEDPELQNGFFYEPTIFSNCNSDMRIVQEEVFGPVLTVETFSSEEEVIELANDTIYGLAGAVWSKDIEKCERVAARLRMGTVWINDFHPYFAQAPWGGYKQSGFGRELGKIGLEEYTEVKHVYRNTKPAAVNWFNS	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	490 (454)
Sequences:	36465 (21902)
Seq/√Len:	1027.9

ECOLI - BETB GABD PUUC ABDH ALDB FEAB ALDA ASTD SAD EUTE PUTA PAAZ PROA
BACSU - BETB ALDH4 ROCA ROCA2 ALDH1 ALDH5 IOLA ALDY GABD ALDH3 ALDH2 PROA
HALSA - Q9HMJ6 Q9HQZ2 Q9HRB5 Q9HR91
SULSO - Q97YT9 KGSDH GAPN Q97XS9 Q97XA5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
293_D	396_S	4.900	1.00
237_R	241_G	3.560	1.00
293_D	394_T	3.109	1.00
265_E	302_E	3.066	1.00
296_H	394_T	2.937	1.00
21_S	33_T	2.879	1.00
353_K	367_E	2.780	1.00
50_R	219_D	2.764	1.00
260_K	292_E	2.705	1.00
340_I	379_R	2.608	1.00
269_D	306_R	2.606	1.00
375_N	378_M	2.603	1.00
328_A	332_A	2.586	1.00
185_K	188_K	2.568	1.00
339_E	343_E	2.488	1.00
300_L	392_V	2.460	1.00
260_K	294_A	2.457	1.00
80_D	83_E	2.412	1.00
21_S	30_E	2.387	1.00
418_S	424_C	2.370	1.00
78_R	111_Q	2.310	1.00
191_E	197_K	2.254	1.00
335_E	339_E	2.180	1.00
38_G	41_D	2.179	1.00
81_L	104_D	2.156	1.00
76_L	192_E	2.142	1.00
50_R	221_D	2.136	1.00
338_V	366_Y	2.134	1.00
82_E	100_K	2.129	1.00
73_I	190_M	2.099	1.00
409_I	455_Q	2.073	1.00
340_I	344_E	2.027	1.00
178_I	327_S	2.018	1.00
139_E	474_K	2.001	1.00
398_E	423_K	1.998	1.00
347_K	373_N	1.979	1.00
212_D	216_V	1.979	1.00
335_E	354_R	1.953	1.00
216_V	238_A	1.950	1.00
83_E	185_K	1.941	1.00
335_E	366_Y	1.923	1.00
256_N	271_A	1.921	1.00
298_Q	302_E	1.921	1.00
304_V	308_K	1.916	1.00
426_R	430_R	1.913	1.00
349_E	372_S	1.907	1.00
138_R	468_E	1.900	1.00
234_K	237_R	1.863	1.00
233_K	455_Q	1.843	1.00
325_L	334_V	1.830	1.00
69_I	195_V	1.810	1.00
76_L	79_R	1.810	1.00
80_D	192_E	1.793	1.00
342_I	348_L	1.792	1.00
261_D	423_K	1.790	1.00
47_A	219_D	1.789	1.00
43_I	213_E	1.783	1.00
381_V	393_E	1.766	1.00
290_L	404_L	1.740	1.00
30_E	33_T	1.726	1.00
43_I	47_A	1.704	1.00
76_L	193_A	1.698	1.00
432_R	454_K	1.687	1.00
138_R	471_T	1.660	1.00
71_L	111_Q	1.637	1.00
87_L	185_K	1.635	1.00
347_K	372_S	1.633	1.00
304_V	349_E	1.626	1.00
187_F	202_L	1.623	1.00
54_D	57_E	1.621	1.00
396_S	400_E	1.618	1.00
400_E	403_E	1.618	1.00
96_L	100_K	1.605	1.00
376_S	404_L	1.604	1.00
292_E	395_F	1.602	1.00
78_R	107_A	1.594	1.00
307_A	370_I	1.579	1.00
371_F	380_I	1.576	1.00
62_S	65_E	1.575	1.00
76_L	189_L	1.570	1.00
301_A	305_K	1.562	1.00
296_H	300_L	1.558	1.00
302_E	305_K	1.556	1.00
336_K	379_R	1.555	1.00
398_E	426_R	1.543	1.00
271_A	299_F	1.541	1.00
110_F	162_A	1.539	1.00
328_A	364_F	1.537	1.00
19_I	33_T	1.536	1.00
276_F	307_A	1.534	1.00
72_K	75_E	1.530	1.00
75_E	79_R	1.526	1.00
268_V	302_E	1.517	1.00
290_L	401_V	1.510	1.00
206_P	209_T	1.506	1.00
53_F	59_S	1.496	1.00
264_L	302_E	1.482	1.00
170_T	199_V	1.480	1.00
61_L	65_E	1.479	1.00
65_E	68_K	1.478	1.00
379_R	383_E	1.473	1.00
60_S	430_R	1.472	1.00
29_E	362_N	1.462	1.00
259_F	423_K	1.456	1.00
81_L	100_K	1.455	1.00
86_E	90_L	1.452	1.00
290_L	395_F	1.436	1.00
188_K	192_E	1.431	1.00
43_I	217_N	1.430	1.00
306_R	309_R	1.428	1.00
270_Q	417_W	1.426	1.00
297_D	394_T	1.424	1.00
339_E	342_I	1.422	1.00
74_A	111_Q	1.416	1.00
137_I	429_A	1.414	1.00
71_L	118_D	1.414	1.00
311_K	319_E	1.412	1.00
296_H	372_S	1.411	1.00
289_L	390_L	1.407	1.00
400_E	404_L	1.405	1.00
271_A	289_L	1.404	1.00
298_Q	301_A	1.394	1.00
291_V	299_F	1.389	1.00
348_L	371_F	1.384	1.00
82_E	86_E	1.380	1.00
23_I	30_E	1.376	1.00
80_D	185_K	1.373	1.00
414_G	433_M	1.372	1.00
116_L	119_K	1.368	1.00
18_Q	36_E	1.365	1.00
110_F	158_S	1.350	1.00
334_V	387_G	1.347	1.00
260_K	423_K	1.343	1.00
146_Q	171_I	1.337	1.00
86_E	316_F	1.336	1.00
331_R	335_E	1.333	1.00
41_D	44_K	1.332	1.00
344_E	379_R	1.320	1.00
222_L	247_A	1.319	1.00
236_M	458_F	1.309	1.00
28_Q	362_N	1.309	1.00
399_E	430_R	1.290	1.00
332_A	336_K	1.288	1.00
337_Y	385_V	1.288	1.00
24_N	27_N	1.287	1.00
395_F	404_L	1.286	1.00
328_A	331_R	1.280	1.00
75_E	111_Q	1.278	1.00
297_D	301_A	1.278	1.00
259_F	395_F	1.266	1.00
300_L	304_V	1.258	1.00
89_S	99_S	1.257	1.00
157_A	173_M	1.255	1.00
257_I	401_V	1.252	1.00
331_R	354_R	1.252	1.00
305_K	308_K	1.250	1.00
259_F	427_V	1.249	1.00
187_F	200_A	1.245	1.00
311_K	321_E	1.245	1.00
308_K	350_T	1.243	1.00
292_E	397_S	1.241	1.00
331_R	366_Y	1.240	1.00
53_F	170_T	1.229	1.00
336_K	340_I	1.226	1.00
295_I	298_Q	1.223	1.00
302_E	306_R	1.221	1.00
212_D	238_A	1.209	1.00
36_E	206_P	1.208	1.00
47_A	51_R	1.207	1.00
74_A	78_R	1.206	1.00
377_D	382_Q	1.202	1.00
465_I	468_E	1.201	1.00
402_I	427_V	1.200	1.00
397_S	400_E	1.195	1.00
464_K	468_E	1.193	1.00
292_E	295_I	1.186	1.00
138_R	473_V	1.176	1.00
86_E	96_L	1.163	1.00
123_E	464_K	1.163	1.00
305_K	309_R	1.155	1.00
61_L	69_I	1.155	1.00
39_R	213_E	1.154	1.00
46_I	220_V	1.149	1.00
135_K	425_E	1.148	1.00
376_S	407_D	1.147	1.00
46_I	219_D	1.147	1.00
303_L	390_L	1.145	1.00
428_A	476_V	1.140	1.00
313_G	320_T	1.140	1.00
300_L	372_S	1.140	1.00
89_S	315_G	1.138	1.00
141_I	222_L	1.136	1.00
234_K	238_A	1.135	1.00
414_G	436_V	1.128	1.00
184_I	204_L	1.126	1.00
424_C	438_I	1.124	1.00
198_G	201_N	1.123	1.00
190_M	200_A	1.113	1.00
399_E	403_E	1.112	1.00
212_D	234_K	1.110	1.00
299_F	303_L	1.110	1.00
84_L	185_K	1.106	1.00
230_E	234_K	1.105	1.00
72_K	76_L	1.101	1.00
20_R	36_E	1.099	1.00
46_I	217_N	1.098	1.00
48_A	201_N	1.097	1.00
42_A	210_V	1.087	1.00
399_E	426_R	1.085	1.00
346_A	371_F	1.081	1.00
355_P	367_E	1.081	1.00
177_E	208_A	1.079	1.00
231_T	234_K	1.078	1.00
177_E	206_P	1.078	1.00
356_E	361_Q	1.077	1.00
382_Q	409_I	1.074	1.00
451_G	460_R	1.074	1.00
236_M	246_I	1.072	1.00
256_N	286_G	1.072	1.00
71_L	115_G	1.072	1.00
300_L	349_E	1.070	1.00
460_R	472_E	1.065	1.00
465_I	473_V	1.064	1.00
73_I	195_V	1.064	1.00
32_A	181_L	1.060	1.00
28_Q	364_F	1.058	1.00
36_E	209_T	1.057	1.00
257_I	427_V	1.054	1.00
308_K	367_E	1.049	1.00
73_I	189_L	1.048	1.00
341_G	371_F	1.046	1.00
161_I	200_A	1.045	1.00
402_I	430_R	1.042	1.00
145_G	220_V	1.037	1.00
24_N	314_N	1.034	1.00
304_V	350_T	1.030	1.00
146_Q	224_S	1.029	1.00
161_I	171_I	1.029	1.00
340_I	343_E	1.024	1.00
344_E	378_M	1.021	1.00
73_I	110_F	1.018	1.00
257_I	405_A	1.017	1.00
382_Q	407_D	1.017	1.00
57_E	61_L	1.011	1.00
420_D	423_K	1.006	1.00
213_E	217_N	1.005	1.00
263_D	419_K	1.004	1.00
26_F	315_G	1.000	1.00
331_R	364_F	0.997	1.00
263_D	266_V	0.996	1.00
67_G	118_D	0.996	1.00
152_Y	282_V	0.994	1.00
395_F	401_V	0.992	1.00
123_E	465_I	0.988	1.00
106_I	158_S	0.988	1.00
266_V	270_Q	0.986	1.00
84_L	189_L	0.984	1.00
188_K	191_E	0.983	1.00
117_A	166_A	0.983	1.00
233_K	243_V	0.982	1.00
272_L	306_R	0.980	1.00
50_R	54_D	0.974	1.00
310_I	322_S	0.971	1.00
398_E	427_V	0.970	1.00
85_A	100_K	0.968	1.00
177_E	207_G	0.967	1.00
83_E	86_E	0.965	1.00
143_V	170_T	0.965	1.00
52_A	170_T	0.964	1.00
336_K	339_E	0.957	1.00
374_C	378_M	0.956	1.00
71_L	114_A	0.953	1.00
141_I	245_K	0.953	1.00
137_I	476_V	0.953	1.00
54_D	403_E	0.953	1.00
39_R	43_I	0.952	1.00
453_Y	472_E	0.952	1.00
253_K	287_S	0.949	1.00
351_G	367_E	0.945	1.00
403_E	407_D	0.943	1.00
314_N	317_H	0.942	1.00
39_R	209_T	0.940	1.00
80_D	188_K	0.940	1.00
54_D	432_R	0.939	1.00
76_L	80_D	0.938	1.00
79_R	192_E	0.935	1.00
145_G	214_L	0.935	1.00
184_I	202_L	0.931	1.00
265_E	298_Q	0.930	1.00
80_D	189_L	0.929	1.00
274_A	286_G	0.920	1.00
415_A	441_F	0.919	1.00
236_M	240_S	0.919	1.00
90_L	316_F	0.917	1.00
24_N	90_L	0.916	1.00
144_C	222_L	0.916	1.00
351_G	369_T	0.915	1.00
106_I	154_L	0.914	1.00
216_V	241_G	0.911	1.00
425_E	429_A	0.908	1.00
337_Y	340_I	0.908	1.00
68_K	72_K	0.907	1.00
334_V	389_V	0.902	1.00
134_S	448_A	0.901	1.00
92_T	179_T	0.899	1.00
67_G	71_L	0.894	1.00
63_G	67_G	0.891	1.00
264_L	268_V	0.891	1.00
255_P	414_G	0.891	1.00
44_K	48_A	0.885	1.00
178_I	329_E	0.885	1.00
275_V	287_S	0.884	1.00
236_M	239_A	0.883	1.00
139_E	429_A	0.881	1.00
187_F	191_E	0.881	1.00
139_E	453_Y	0.880	1.00
334_V	385_V	0.878	1.00
256_N	417_W	0.877	1.00
23_I	364_F	0.877	1.00
59_S	432_R	0.874	1.00
233_K	237_R	0.874	1.00
135_K	478_R	0.873	1.00
60_S	429_A	0.872	1.00
94_K	102_D	0.867	1.00
259_F	418_S	0.865	1.00
296_H	392_V	0.865	1.00
42_A	145_G	0.860	1.00
184_I	188_K	0.857	1.00
414_G	431_L	0.854	1.00
167_A	471_T	0.850	1.00
143_V	220_V	0.850	1.00
332_A	335_E	0.850	1.00
259_F	398_E	0.848	1.00
221_D	432_R	0.846	1.00
393_E	404_L	0.846	1.00
24_N	29_E	0.842	1.00
77_I	106_I	0.841	1.00
297_D	300_L	0.838	1.00
337_Y	379_R	0.836	1.00
223_I	239_A	0.835	1.00
58_W	199_V	0.835	1.00
74_A	114_A	0.835	1.00
448_A	475_H	0.832	1.00
228_G	231_T	0.830	1.00
40_E	44_K	0.826	1.00
421_I	424_C	0.825	1.00
26_F	365_F	0.825	1.00
245_K	472_E	0.825	1.00
346_A	378_M	0.823	1.00
268_V	303_L	0.821	1.00
57_E	60_S	0.821	1.00
54_D	60_S	0.818	1.00
44_K	47_A	0.816	1.00
268_V	306_R	0.813	1.00
342_I	371_F	0.812	1.00
48_A	198_G	0.810	1.00
376_S	393_E	0.810	1.00
141_I	472_E	0.809	1.00
329_E	332_A	0.809	1.00
173_M	183_T	0.809	1.00
164_A	171_I	0.807	1.00
20_R	206_P	0.807	1.00
40_E	43_I	0.806	1.00
301_A	304_V	0.805	1.00
175_P	204_L	0.805	1.00
67_G	114_A	0.804	1.00
49_A	201_N	0.803	1.00
37_G	41_D	0.803	1.00
157_A	161_I	0.803	1.00
71_L	75_E	0.803	1.00
163_P	466_G	0.800	1.00
236_M	243_V	0.799	1.00
402_I	406_N	0.796	1.00
160_K	461_E	0.794	1.00
268_V	299_F	0.793	1.00
158_S	186_V	0.793	1.00
78_R	81_L	0.789	1.00
52_A	199_V	0.788	1.00
208_A	212_D	0.783	1.00
267_A	271_A	0.781	1.00
232_G	250_L	0.778	1.00
28_Q	328_A	0.777	1.00
233_K	241_G	0.774	1.00
338_V	389_V	0.774	1.00
141_I	169_N	0.773	1.00
433_M	436_V	0.772	1.00
401_V	404_L	0.770	1.00
97_E	321_E	0.769	1.00
31_I	90_L	0.768	1.00
416_V	427_V	0.765	1.00
395_F	400_E	0.765	1.00
90_L	181_L	0.763	1.00
205_G	210_V	0.761	1.00
123_E	126_S	0.761	1.00
92_T	326_I	0.758	1.00
264_L	295_I	0.757	1.00
232_G	248_L	0.755	1.00
341_G	385_V	0.755	1.00
195_V	199_V	0.754	1.00
229_I	455_Q	0.751	1.00
258_V	299_F	0.750	1.00
223_I	235_I	0.748	1.00
89_S	96_L	0.748	1.00
78_R	104_D	0.748	1.00
372_S	394_T	0.748	1.00
154_L	182_T	0.748	1.00
317_H	320_T	0.747	1.00
69_I	193_A	0.746	1.00
255_P	405_A	0.745	1.00
64_L	118_D	0.745	1.00
70_V	166_A	0.744	1.00
345_G	378_M	0.743	1.00
51_R	54_D	0.740	1.00
37_G	45_A	0.739	1.00
356_E	362_N	0.738	1.00
342_I	353_K	0.736	1.00
292_E	398_E	0.736	1.00
211_G	215_A	0.735	1.00
210_V	213_E	0.735	1.00
352_G	369_T	0.731	1.00
146_Q	160_K	0.731	1.00
215_A	235_I	0.731	1.00
310_I	321_E	0.730	1.00
312_L	355_P	0.727	1.00
239_A	246_I	0.725	1.00
145_G	223_I	0.723	1.00
23_I	28_Q	0.723	1.00
225_F	231_T	0.723	1.00
265_E	306_R	0.722	1.00
334_V	366_Y	0.721	1.00
303_L	370_I	0.721	1.00
85_A	96_L	0.720	1.00
307_A	350_T	0.719	1.00
333_K	336_K	0.719	1.00
254_N	287_S	0.718	1.00
141_I	221_D	0.716	1.00
100_K	318_A	0.716	1.00
96_L	316_F	0.715	1.00
49_A	170_T	0.713	1.00
337_Y	383_E	0.713	1.00
83_E	188_K	0.711	1.00
82_E	96_L	0.709	1.00
291_V	295_I	0.707	1.00
296_H	373_N	0.706	1.00
157_A	183_T	0.704	1.00
421_I	478_R	0.704	1.00
438_I	478_R	0.703	1.00
54_D	59_S	0.703	1.00
148_T	157_A	0.703	1.00
178_I	326_I	0.703	1.00
58_W	69_I	0.702	1.00
134_S	475_H	0.699	1.00
421_I	425_E	0.698	1.00
43_I	219_D	0.698	1.00
267_A	299_F	0.697	1.00
419_K	422_E	0.696	1.00
209_T	212_D	0.695	1.00
85_A	89_S	0.694	1.00
77_I	107_A	0.693	1.00
173_M	200_A	0.690	1.00
19_I	35_S	0.689	1.00
52_A	57_E	0.688	1.00
50_R	53_F	0.687	1.00
18_Q	209_T	0.686	1.00
215_A	238_A	0.683	1.00
238_A	241_G	0.681	1.00
279_A	322_S	0.678	1.00
195_V	200_A	0.677	1.00
237_R	240_S	0.675	1.00
304_V	307_A	0.673	1.00
59_S	430_R	0.672	1.00
87_L	181_L	0.671	1.00
72_K	193_A	0.671	1.00
290_L	381_V	0.670	1.00
327_S	330_H	0.669	1.00
307_A	310_I	0.666	1.00
258_V	267_A	0.665	1.00
259_F	292_E	0.660	1.00
330_H	333_K	0.659	1.00
290_L	376_S	0.658	1.00
75_E	78_R	0.657	1.00
63_G	117_A	0.657	1.00
65_E	69_I	0.656	1.00
428_A	438_I	0.655	1.00
245_K	469_E	0.655	1.00
271_A	303_L	0.655	1.00
137_I	474_K	0.654	1.00
134_S	477_Y	0.651	1.00
268_V	272_L	0.651	1.00
344_E	377_D	0.649	1.00
261_D	418_S	0.649	1.00
266_V	269_D	0.648	1.00
272_L	303_L	0.646	1.00
157_A	186_V	0.646	1.00
58_W	165_L	0.646	1.00
42_A	46_I	0.645	1.00
24_N	316_F	0.645	1.00
88_E	91_D	0.644	1.00
120_D	471_T	0.643	1.00
468_E	471_T	0.643	1.00
376_S	381_V	0.642	1.00
266_V	419_K	0.641	1.00
468_E	473_V	0.640	1.00
329_E	333_K	0.640	1.00
145_G	211_G	0.640	1.00
264_L	298_Q	0.639	1.00
289_L	299_F	0.639	1.00
81_L	85_A	0.638	1.00
133_E	425_E	0.638	1.00
261_D	420_D	0.637	1.00
272_L	310_I	0.637	1.00
54_D	430_R	0.637	1.00
432_R	453_Y	0.636	1.00
169_N	471_T	0.635	1.00
190_M	195_V	0.634	1.00
42_A	213_E	0.632	1.00
404_L	407_D	0.632	1.00
48_A	197_K	0.632	1.00
59_S	140_P	0.631	1.00
425_E	478_R	0.630	1.00
366_Y	369_T	0.627	1.00
59_S	139_E	0.626	1.00
424_C	428_A	0.625	1.00
103_M	107_A	0.623	1.00
247_A	469_E	0.619	1.00
398_E	402_I	0.616	1.00
45_A	203_V	0.616	1.00
207_G	211_G	0.615	1.00
312_L	322_S	0.614	1.00
74_A	107_A	0.613	1.00
328_A	354_R	0.613	1.00
236_M	248_L	0.613	1.00
303_L	392_V	0.612	1.00
215_A	223_I	0.611	1.00
39_R	212_D	0.611	1.00
35_S	204_L	0.610	1.00
374_C	380_I	0.609	1.00
120_D	467_L	0.607	1.00
374_C	381_V	0.606	1.00
291_V	296_H	0.606	1.00
22_I	91_D	0.605	1.00
39_R	216_V	0.604	1.00
177_E	333_K	0.603	1.00
185_K	189_L	0.603	1.00
160_K	224_S	0.603	1.00
86_E	89_S	0.603	1.00
88_E	99_S	0.603	1.00
355_P	361_Q	0.601	1.00
350_T	370_I	0.601	1.00
94_K	98_E	0.599	1.00
314_N	320_T	0.598	1.00
161_I	173_M	0.598	1.00
376_S	403_E	0.598	1.00
397_S	403_E	0.597	1.00
331_R	355_P	0.597	1.00
338_V	371_F	0.596	1.00
208_A	234_K	0.596	1.00
335_E	338_V	0.595	1.00
88_E	182_T	0.594	1.00
348_L	351_G	0.594	1.00
154_L	186_V	0.594	1.00
22_I	32_A	0.593	1.00
274_A	441_F	0.592	1.00
205_G	211_G	0.592	1.00
89_S	316_F	0.591	1.00
94_K	152_Y	0.591	1.00
47_A	50_R	0.591	1.00
31_I	181_L	0.590	1.00
265_E	305_K	0.590	1.00
422_E	425_E	0.589	1.00
229_I	233_K	0.589	1.00
416_V	438_I	0.589	1.00
77_I	110_F	0.588	1.00
77_I	186_V	0.585	1.00
63_G	166_A	0.584	1.00
418_S	423_K	0.584	1.00
177_E	234_K	0.583	1.00
135_K	476_V	0.580	1.00
401_V	405_A	0.580	1.00
352_G	367_E	0.579	1.00
312_L	321_E	0.577	1.00
325_L	330_H	0.576	1.00
144_C	169_N	0.575	1.00
422_E	426_R	0.574	1.00
385_V	389_V	0.574	1.00
291_V	392_V	0.571	1.00
112_Y	116_L	0.570	1.00
256_N	415_A	0.570	1.00
84_L	154_L	0.570	1.00
275_V	390_L	0.568	1.00
45_A	201_N	0.568	1.00
416_V	424_C	0.568	1.00
402_I	426_R	0.567	1.00
64_L	68_K	0.565	1.00
167_A	467_L	0.562	1.00
88_E	102_D	0.562	1.00
256_N	289_L	0.560	1.00
85_A	103_M	0.559	1.00
63_G	121_G	0.558	1.00
264_L	299_F	0.558	1.00
77_I	154_L	0.557	1.00
222_L	469_E	0.557	1.00
172_V	201_N	0.556	1.00
373_N	394_T	0.556	1.00
338_V	369_T	0.555	1.00
51_R	57_E	0.553	1.00
68_K	71_L	0.553	1.00
74_A	110_F	0.553	1.00
348_L	369_T	0.553	1.00
264_L	267_A	0.552	1.00
48_A	52_A	0.552	1.00
37_G	203_V	0.551	1.00
18_Q	38_G	0.550	1.00
34_V	180_P	0.549	1.00
212_D	215_A	0.548	1.00
311_K	317_H	0.547	1.00
398_E	430_R	0.547	1.00
380_I	385_V	0.546	1.00
143_V	221_D	0.545	1.00
289_L	392_V	0.545	1.00
165_L	200_A	0.544	1.00
50_R	143_V	0.542	1.00
103_M	154_L	0.542	1.00
282_V	285_A	0.541	1.00
437_W	440_D	0.541	1.00
49_A	172_V	0.541	1.00
254_N	413_A	0.540	1.00
402_I	431_L	0.540	1.00
246_I	458_F	0.539	1.00
269_D	273_N	0.539	1.00
371_F	374_C	0.536	1.00
436_V	474_K	0.536	1.00
209_T	213_E	0.533	1.00
104_D	107_A	0.532	1.00
405_A	431_L	0.532	1.00
354_R	367_E	0.531	1.00
115_G	118_D	0.531	1.00
186_V	190_M	0.530	1.00
335_E	342_I	0.530	1.00
349_E	373_N	0.530	1.00
224_S	470_Y	0.529	1.00
230_E	329_E	0.527	1.00
260_K	395_F	0.525	1.00
170_T	201_N	0.525	1.00
261_D	419_K	0.524	1.00
139_E	432_R	0.523	1.00
325_L	366_Y	0.523	1.00
22_I	180_P	0.523	1.00
113_Y	163_P	0.522	1.00
116_L	464_K	0.522	1.00
81_L	107_A	0.521	1.00
136_I	473_V	0.520	1.00
155_L	159_W	0.520	1.00
403_E	430_R	0.520	1.00
286_G	415_A	0.519	1.00
144_C	171_I	0.519	1.00
432_R	472_E	0.519	1.00
333_K	337_Y	0.519	1.00
191_E	198_G	0.518	1.00
92_T	278_H	0.518	1.00
73_I	76_L	0.518	1.00
159_W	462_L	0.518	1.00
293_D	296_H	0.517	1.00
49_A	143_V	0.516	1.00
262_A	267_A	0.516	1.00
304_V	370_I	0.514	1.00
427_V	431_L	0.513	1.00
132_S	440_D	0.511	1.00
45_A	172_V	0.511	1.00
34_V	181_L	0.510	1.00
84_L	103_M	0.507	1.00
100_K	104_D	0.507	1.00
342_I	346_A	0.506	1.00
105_D	155_L	0.506	1.00
229_I	409_I	0.503	1.00
36_E	177_E	0.503	1.00
379_R	382_Q	0.502	1.00
284_S	443_P	0.501	1.00
177_E	230_E	0.500	1.00
276_F	310_I	0.500	1.00
85_A	99_S	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4qtoA	4	0.9959	100	0.032	Contact Map
4o5hA	4	0.9735	100	0.036	Contact Map
3ek1A	5	0.9673	100	0.036	Contact Map
4yweA	5	0.9673	100	0.037	Contact Map
1a4sA	4	0.9857	100	0.038	Contact Map
4pxlA	4	0.9816	100	0.038	Contact Map
4pz2A	4	0.9816	100	0.039	Contact Map
3u4jA	4	0.9857	100	0.04	Contact Map
4qf6A	4	0.9714	100	0.04	Contact Map
2d4eA	4	0.9918	100	0.04	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0121 seconds.