PTF3A - BACSU - GREMLIN Contacts

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PTF3A - PTS system fructose-specific EIIABC component

UniProt:	P71012	Sequences: MKITELLTKHTIKLNIESKEKENVIDEMVTVLDKAGKLNDRQAYKEAILNRESQSSTGIGEGIAIPHAKTASVINPAIAFGRSKDGVDYESLDGQPAHLVFMIAATEGANNTHLEALSRLSTLLMREEIRKQLLEAESEDAIIDIINQHDKDDDEEEEEEEAAPAPAGKGKILAVTACPTGIAHTFMAADALKEKAKELGVEIKVETNGSSGIKHKLTAQEIEDAPAIIVAADKQVEMERFKGKRVLQVPVTAGIRRPQELIEKAMNQDAPIYQGSGGGSAASNDDEEAKGKSGSGIGNTFYKHLMSGVSNMLPFVVGGGILVAISFFWGIHSADPNDPSYNTFAAALNFIGGDNALKLIVAVLAGFIAMSIADRPGFAPGMVGGFMATQANAGFLGGLIAGFLAGYVVILLKKVFTFIPQSLDGLKPVLIYPLFGIFITGVLMQFVVNTPVAAFMNFLTNWLESLGTGNLVLMGIILGGMMAIDMGGPLNKAAFTFGIAMIDAGNYAPHAAIMAGGMVPPLGIALATTIFRNKFTQRDREAGITCYFMGAAFVTEGAIPFAAADPLRVIPAAVVGAAVAGGLTEFFRVTLPAPHGGVFVAFITNHPMLYLLSIVIGAVVMAIILGIVKKPVTEK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	635 (616)
Sequences:	983 (580)
Seq/√Len:	23.4

ECOLI - HRSA PTFBC PTFLB
BACSU - PTF3A PTN3B

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
173_L	228_I	5.926	1.00
527_A	535_F	5.426	1.00
523_G	621_M	5.286	1.00
515_A	614_I	4.866	1.00
484_I	490_L	4.631	1.00
373_A	377_G	4.389	1.00
529_T	547_Y	4.247	1.00
227_A	265_A	4.212	1.00
259_Q	263_E	4.199	1.00
199_L	263_E	4.151	1.00
384_G	401_A	4.098	1.00
213_I	216_K	4.093	1.00
408_V	439_I	3.939	1.00
196_A	203_I	3.921	1.00
199_L	259_Q	3.789	1.00
9_K	140_D	3.782	1.00
220_Q	224_D	3.728	1.00
174_A	205_V	3.704	1.00
201_V	262_I	3.693	1.00
361_V	398_G	3.644	1.00
528_T	543_G	3.611	1.00
242_K	274_Q	3.530	1.00
71_A	107_E	3.486	1.00
257_R	260_E	3.255	1.00
91_S	97_A	3.241	1.00
359_L	386_F	3.218	1.00
195_K	198_E	3.183	1.00
20_E	23_N	3.180	1.00
590_T	605_N	3.156	1.00
171_K	224_D	3.105	1.00
219_A	223_E	3.072	1.00
30_T	41_R	2.982	1.00
26_D	45_K	2.902	0.99
575_V	624_I	2.884	0.99
326_S	350_F	2.855	0.99
198_E	259_Q	2.786	0.99
263_E	267_N	2.783	0.99
480_G	574_V	2.760	0.99
171_K	226_P	2.704	0.99
612_L	616_I	2.683	0.99
33_D	38_L	2.677	0.99
379_A	437_I	2.650	0.99
47_A	70_T	2.500	0.98
496_T	499_I	2.492	0.98
253_A	257_R	2.444	0.98
304_H	371_S	2.423	0.98
48_I	102_M	2.389	0.98
204_K	221_E	2.384	0.98
311_N	378_F	2.347	0.98
29_V	45_K	2.341	0.98
245_R	268_Q	2.309	0.97
583_L	587_F	2.221	0.97
480_G	578_A	2.199	0.96
264_K	269_D	2.196	0.96
524_I	625_L	2.171	0.96
515_A	580_A	2.160	0.96
533_N	631_P	2.130	0.96
98_H	134_L	2.127	0.96
367_F	370_M	2.119	0.96
242_K	275_G	2.116	0.95
455_F	458_F	2.102	0.95
609_L	612_L	2.089	0.95
227_A	247_L	2.087	0.95
483_A	577_A	2.075	0.95
137_E	141_A	2.057	0.95
349_N	352_G	2.054	0.95
138_S	141_A	2.053	0.95
42_Q	46_E	2.018	0.94
537_Q	540_R	1.996	0.94
170_G	226_P	1.990	0.94
569_V	625_L	1.965	0.93
18_S	24_V	1.957	0.93
369_A	405_A	1.956	0.93
409_V	436_G	1.921	0.92
346_A	350_F	1.912	0.92
363_V	382_M	1.898	0.92
169_K	202_E	1.892	0.92
195_K	259_Q	1.863	0.91
190_D	193_K	1.850	0.91
484_I	574_V	1.833	0.91
535_F	626_G	1.818	0.90
435_F	439_I	1.814	0.90
195_K	199_L	1.799	0.90
97_A	100_V	1.798	0.90
315_F	382_M	1.746	0.88
537_Q	541_E	1.735	0.88
587_F	609_L	1.722	0.88
527_A	626_G	1.717	0.87
50_N	54_Q	1.697	0.87
130_R	134_L	1.692	0.87
199_L	262_I	1.689	0.86
172_I	201_V	1.672	0.86
40_D	43_A	1.650	0.85
25_I	89_Y	1.650	0.85
541_E	544_I	1.638	0.85
530_I	547_Y	1.633	0.85
396_L	400_I	1.633	0.85
264_K	267_N	1.623	0.84
131_K	135_E	1.616	0.84
126_R	149_H	1.609	0.84
369_A	381_G	1.598	0.83
206_E	240_R	1.596	0.83
331_I	334_A	1.585	0.83
132_Q	148_Q	1.579	0.82
118_S	122_T	1.574	0.82
458_F	462_W	1.565	0.82
534_K	626_G	1.558	0.82
480_G	516_G	1.554	0.81
318_G	437_I	1.547	0.81
495_F	510_H	1.544	0.81
144_D	148_Q	1.543	0.81
80_F	142_I	1.537	0.81
381_G	405_A	1.534	0.81
193_K	197_K	1.529	0.80
245_R	272_I	1.528	0.80
127_E	131_K	1.519	0.80
336_P	342_N	1.516	0.80
365_A	401_A	1.512	0.80
609_L	616_I	1.509	0.79
50_N	53_S	1.508	0.79
619_V	622_A	1.502	0.79
460_T	464_E	1.497	0.79
613_S	616_I	1.495	0.79
192_L	203_I	1.493	0.79
13_K	27_E	1.481	0.78
458_F	461_N	1.466	0.77
478_L	509_P	1.464	0.77
297_I	300_T	1.458	0.77
589_V	609_L	1.457	0.77
570_I	574_V	1.452	0.77
345_A	352_G	1.445	0.76
565_D	568_R	1.445	0.76
30_T	34_K	1.443	0.76
262_I	266_M	1.440	0.76
483_A	520_P	1.440	0.76
524_I	546_C	1.439	0.76
349_N	353_G	1.437	0.76
8_T	37_K	1.431	0.76
531_F	626_G	1.424	0.75
358_K	386_F	1.419	0.75
534_K	631_P	1.414	0.75
457_N	461_N	1.410	0.74
507_Y	592_P	1.396	0.74
616_I	620_V	1.396	0.74
24_V	83_S	1.389	0.73
583_L	613_S	1.385	0.73
483_A	555_T	1.374	0.73
232_A	248_Q	1.371	0.72
530_I	618_A	1.364	0.72
16_I	27_E	1.363	0.72
373_A	410_I	1.352	0.71
454_A	458_F	1.350	0.71
579_V	620_V	1.349	0.71
500_A	503_D	1.349	0.71
523_G	573_A	1.349	0.71
618_A	622_A	1.343	0.71
83_S	98_H	1.341	0.71
302_Y	306_M	1.323	0.70
16_I	81_G	1.320	0.69
177_A	234_K	1.314	0.69
623_I	627_I	1.314	0.69
249_V	261_L	1.313	0.69
579_V	616_I	1.311	0.69
173_L	221_E	1.299	0.68
355_N	387_M	1.297	0.68
18_S	27_E	1.294	0.68
575_V	616_I	1.291	0.68
409_V	412_L	1.285	0.67
15_N	82_R	1.274	0.67
25_I	45_K	1.267	0.66
251_V	254_G	1.267	0.66
340_S	352_G	1.264	0.66
114_L	125_M	1.258	0.66
171_K	202_E	1.257	0.66
170_G	266_M	1.252	0.65
26_D	29_V	1.252	0.65
114_L	121_S	1.243	0.65
611_L	615_V	1.241	0.65
14_L	82_R	1.241	0.65
384_G	440_T	1.232	0.64
118_S	211_S	1.231	0.64
22_E	49_L	1.227	0.64
323_V	357_L	1.223	0.63
571_P	628_V	1.222	0.63
254_G	257_R	1.222	0.63
11_T	35_A	1.220	0.63
371_S	423_L	1.215	0.63
254_G	260_E	1.209	0.62
207_T	215_H	1.208	0.62
174_A	232_A	1.206	0.62
525_A	529_T	1.206	0.62
573_A	621_M	1.201	0.62
239_E	275_G	1.197	0.62
182_I	425_G	1.196	0.62
23_N	26_D	1.195	0.62
345_A	349_N	1.193	0.61
476_I	582_G	1.189	0.61
32_L	44_Y	1.188	0.61
333_S	342_N	1.185	0.61
583_L	616_I	1.180	0.61
125_M	145_I	1.179	0.60
210_S	428_P	1.178	0.60
400_I	404_L	1.177	0.60
526_L	618_A	1.174	0.60
217_L	222_I	1.173	0.60
223_E	226_P	1.171	0.60
59_I	114_L	1.167	0.60
127_E	130_R	1.159	0.59
62_G	98_H	1.159	0.59
227_A	258_P	1.151	0.59
476_I	479_G	1.147	0.58
119_R	154_D	1.146	0.58
498_G	513_I	1.144	0.58
341_Y	345_A	1.143	0.58
69_K	110_N	1.141	0.58
29_V	48_I	1.141	0.58
115_E	118_S	1.138	0.58
43_A	46_E	1.136	0.58
522_L	618_A	1.136	0.58
123_L	149_H	1.135	0.57
227_A	262_I	1.118	0.56
356_A	383_V	1.117	0.56
514_M	553_F	1.113	0.56
387_M	449_N	1.112	0.56
31_V	34_K	1.107	0.56
47_A	68_A	1.107	0.56
307_S	370_M	1.107	0.56
49_L	53_S	1.106	0.55
258_P	262_I	1.104	0.55
604_T	610_Y	1.102	0.55
624_I	628_V	1.102	0.55
479_G	610_Y	1.101	0.55
582_G	586_F	1.099	0.55
344_F	352_G	1.098	0.55
19_K	23_N	1.096	0.55
398_G	470_N	1.093	0.55
517_G	553_F	1.090	0.54
46_E	53_S	1.090	0.54
114_L	124_L	1.086	0.54
249_V	253_A	1.085	0.54
530_I	622_A	1.080	0.54
382_M	386_F	1.078	0.54
572_A	628_V	1.069	0.53
434_L	438_F	1.065	0.53
92_L	96_P	1.063	0.52
174_A	203_I	1.061	0.52
194_E	538_R	1.060	0.52
552_A	599_F	1.058	0.52
462_W	465_S	1.058	0.52
76_P	106_T	1.056	0.52
16_I	83_S	1.056	0.52
265_A	269_D	1.052	0.52
393_A	397_G	1.051	0.52
8_T	75_N	1.048	0.51
398_G	506_N	1.047	0.51
499_I	510_H	1.047	0.51
495_F	502_I	1.043	0.51
58_G	92_L	1.039	0.51
350_F	354_D	1.039	0.51
115_E	214_K	1.038	0.51
15_N	84_K	1.038	0.51
39_N	74_I	1.037	0.51
365_A	369_A	1.036	0.51
369_A	377_G	1.033	0.50
508_A	585_E	1.031	0.50
525_A	547_Y	1.022	0.50
210_S	375_R	1.020	0.49
58_G	91_S	1.019	0.49
601_A	604_T	1.017	0.49
348_L	352_G	1.017	0.49
325_I	328_F	1.015	0.49
175_V	208_N	1.009	0.49
127_E	194_E	1.009	0.49
33_D	41_R	1.005	0.48
32_L	48_I	1.005	0.48
238_M	273_Y	1.003	0.48
438_F	442_V	1.003	0.48
227_A	269_D	1.001	0.48
478_L	621_M	1.001	0.48
172_I	266_M	0.997	0.48
194_E	197_K	0.995	0.48
300_T	304_H	0.994	0.48
128_E	132_Q	0.994	0.48
210_S	429_V	0.990	0.47
173_L	217_L	0.989	0.47
297_I	407_Y	0.985	0.47
171_K	221_E	0.983	0.47
482_M	514_M	0.982	0.47
220_Q	223_E	0.978	0.47
47_A	50_N	0.978	0.47
456_M	493_A	0.976	0.46
77_A	81_G	0.973	0.46
367_F	453_A	0.972	0.46
61_E	95_Q	0.968	0.46
601_A	607_P	0.966	0.46
330_G	340_S	0.960	0.45
584_T	589_V	0.960	0.45
295_S	299_N	0.959	0.45
298_G	325_I	0.958	0.45
367_F	378_F	0.957	0.45
586_F	613_S	0.957	0.45
451_P	455_F	0.957	0.45
22_E	30_T	0.956	0.45
582_G	585_E	0.955	0.45
333_S	336_P	0.947	0.44
10_H	35_A	0.946	0.44
572_A	624_I	0.941	0.44
140_D	144_D	0.939	0.44
419_I	427_K	0.938	0.44
348_L	446_F	0.937	0.44
65_I	121_S	0.933	0.43
23_N	172_I	0.932	0.43
331_I	336_P	0.931	0.43
495_F	518_M	0.930	0.43
13_K	31_V	0.928	0.43
514_M	517_G	0.927	0.43
19_K	138_S	0.925	0.43
482_M	553_F	0.925	0.43
195_K	258_P	0.923	0.43
234_K	428_P	0.920	0.43
317_V	542_A	0.919	0.42
172_I	196_A	0.918	0.42
480_G	484_I	0.917	0.42
344_F	438_F	0.917	0.42
110_N	116_A	0.915	0.42
412_L	436_G	0.914	0.42
189_A	193_K	0.914	0.42
499_I	506_N	0.912	0.42
260_E	264_K	0.910	0.42
151_K	155_E	0.907	0.42
344_F	349_N	0.907	0.42
171_K	203_I	0.907	0.42
399_L	500_A	0.905	0.41
50_N	91_S	0.905	0.41
332_H	336_P	0.903	0.41
272_I	574_V	0.903	0.41
486_M	555_T	0.901	0.41
338_D	342_N	0.901	0.41
96_P	305_L	0.900	0.41
18_S	83_S	0.898	0.41
172_I	203_I	0.895	0.41
84_K	135_E	0.895	0.41
140_D	624_I	0.894	0.41
536_T	539_D	0.893	0.41
419_I	431_I	0.890	0.40
551_A	611_L	0.889	0.40
128_E	131_K	0.888	0.40
195_K	263_E	0.888	0.40
141_A	145_I	0.888	0.40
102_M	109_A	0.884	0.40
168_G	224_D	0.883	0.40
68_A	110_N	0.882	0.40
325_I	349_N	0.881	0.40
29_V	49_L	0.880	0.40
378_F	381_G	0.878	0.40
140_D	220_Q	0.878	0.40
201_V	266_M	0.876	0.40
482_M	517_G	0.872	0.39
498_G	504_A	0.870	0.39
346_A	349_N	0.870	0.39
352_G	509_P	0.869	0.39
486_M	580_A	0.860	0.38
83_S	100_V	0.855	0.38
175_V	238_M	0.855	0.38
334_A	337_N	0.855	0.38
317_V	544_I	0.851	0.38
340_S	344_F	0.850	0.38
177_A	232_A	0.849	0.38
519_V	580_A	0.848	0.38
511_A	518_M	0.847	0.38
456_M	546_C	0.844	0.37
510_H	513_I	0.843	0.37
61_E	130_R	0.841	0.37
65_I	125_M	0.839	0.37
28_M	79_A	0.836	0.37
194_E	198_E	0.836	0.37
27_E	83_S	0.836	0.37
520_P	577_A	0.834	0.37
43_A	71_A	0.832	0.37
343_T	346_A	0.831	0.37
591_L	610_Y	0.830	0.36
293_S	296_G	0.828	0.36
313_L	427_K	0.827	0.36
424_D	427_K	0.825	0.36
526_L	622_A	0.824	0.36
38_L	41_R	0.824	0.36
508_A	584_T	0.823	0.36
174_A	201_V	0.822	0.36
439_I	443_L	0.822	0.36
38_L	72_S	0.822	0.36
218_T	221_E	0.821	0.36
65_I	82_R	0.821	0.36
297_I	301_F	0.819	0.36
328_F	598_V	0.818	0.36
109_A	112_T	0.818	0.36
43_A	72_S	0.816	0.36
499_I	503_D	0.816	0.36
12_I	46_E	0.815	0.36
90_E	97_A	0.813	0.35
6_L	118_S	0.812	0.35
518_M	553_F	0.812	0.35
475_G	479_G	0.811	0.35
169_K	224_D	0.810	0.35
175_V	365_A	0.810	0.35
145_I	149_H	0.808	0.35
479_G	515_A	0.807	0.35
552_A	593_A	0.807	0.35
58_G	121_S	0.802	0.35
495_F	584_T	0.802	0.35
366_G	382_M	0.801	0.35
12_I	189_A	0.801	0.35
329_W	332_H	0.801	0.35
102_M	118_S	0.800	0.35
119_R	408_V	0.799	0.35
526_L	529_T	0.798	0.34
574_V	577_A	0.797	0.34
583_L	609_L	0.797	0.34
89_Y	256_R	0.797	0.34
47_A	121_S	0.796	0.34
111_N	121_S	0.795	0.34
411_L	484_I	0.795	0.34
105_A	109_A	0.794	0.34
309_V	316_V	0.792	0.34
476_I	578_A	0.791	0.34
367_F	413_K	0.789	0.34
471_L	508_A	0.784	0.34
456_M	524_I	0.783	0.33
455_F	480_G	0.782	0.33
17_E	23_N	0.781	0.33
429_V	434_L	0.780	0.33
16_I	28_M	0.776	0.33
173_L	506_N	0.775	0.33
76_P	107_E	0.775	0.33
522_L	551_A	0.772	0.33
32_L	77_A	0.769	0.33
14_L	139_E	0.768	0.33
408_V	411_L	0.768	0.33
306_M	496_T	0.766	0.32
472_V	586_F	0.766	0.32
360_I	378_F	0.766	0.32
164_P	281_A	0.765	0.32
502_I	510_H	0.764	0.32
335_D	342_N	0.764	0.32
58_G	82_R	0.761	0.32
37_K	75_N	0.761	0.32
411_L	415_V	0.761	0.32
227_A	268_Q	0.760	0.32
22_E	53_S	0.760	0.32
476_I	620_V	0.759	0.32
127_E	145_I	0.757	0.32
330_G	398_G	0.757	0.32
606_H	609_L	0.754	0.32
81_G	87_V	0.753	0.32
531_F	534_K	0.752	0.32
253_A	264_K	0.752	0.32
344_F	348_L	0.751	0.32
452_V	493_A	0.751	0.32
201_V	455_F	0.751	0.32
48_I	100_V	0.751	0.32
355_N	445_Q	0.750	0.31
46_E	50_N	0.749	0.31
451_P	561_F	0.749	0.31
72_S	259_Q	0.749	0.31
459_L	477_I	0.748	0.31
478_L	513_I	0.748	0.31
45_K	49_L	0.747	0.31
239_E	242_K	0.746	0.31
26_D	48_I	0.746	0.31
23_N	27_E	0.746	0.31
26_D	49_L	0.745	0.31
467_G	586_F	0.745	0.31
203_I	262_I	0.742	0.31
22_E	26_D	0.742	0.31
602_F	605_N	0.741	0.31
472_V	611_L	0.740	0.31
45_K	89_Y	0.740	0.31
565_D	629_K	0.738	0.31
195_K	498_G	0.737	0.31
165_A	282_A	0.734	0.31
455_F	548_F	0.734	0.31
441_G	444_M	0.733	0.30
193_K	258_P	0.733	0.30
136_A	325_I	0.732	0.30
6_L	179_P	0.732	0.30
359_L	382_M	0.731	0.30
332_H	335_D	0.730	0.30
345_A	351_I	0.730	0.30
162_A	166_P	0.729	0.30
26_D	30_T	0.728	0.30
366_G	439_I	0.728	0.30
507_Y	590_T	0.727	0.30
480_G	577_A	0.727	0.30
87_V	100_V	0.724	0.30
8_T	455_F	0.722	0.30
538_R	541_E	0.722	0.30
451_P	454_A	0.720	0.30
22_E	90_E	0.720	0.30
175_V	237_E	0.720	0.30
115_E	211_S	0.717	0.30
511_A	517_G	0.717	0.30
230_V	269_D	0.716	0.29
129_I	146_I	0.715	0.29
305_L	403_F	0.714	0.29
61_E	121_S	0.711	0.29
627_I	631_P	0.710	0.29
12_I	143_I	0.708	0.29
425_G	525_A	0.707	0.29
72_S	195_K	0.707	0.29
502_I	604_T	0.707	0.29
518_M	594_P	0.706	0.29
196_A	205_V	0.706	0.29
19_K	135_E	0.706	0.29
590_T	613_S	0.706	0.29
526_L	530_I	0.706	0.29
69_K	116_A	0.704	0.29
528_T	622_A	0.704	0.29
501_M	564_A	0.704	0.29
345_A	353_G	0.702	0.29
347_A	352_G	0.702	0.29
360_I	398_G	0.701	0.29
329_W	334_A	0.701	0.29
408_V	440_T	0.700	0.29
19_K	167_A	0.700	0.29
452_V	455_F	0.699	0.28
196_A	483_A	0.699	0.28
443_L	479_G	0.696	0.28
192_L	539_D	0.695	0.28
502_I	506_N	0.695	0.28
26_D	223_E	0.693	0.28
13_K	34_K	0.693	0.28
258_P	266_M	0.693	0.28
28_M	102_M	0.692	0.28
163_A	167_A	0.689	0.28
199_L	258_P	0.688	0.28
496_T	510_H	0.682	0.28
412_L	419_I	0.682	0.28
479_G	516_G	0.682	0.28
334_A	367_F	0.681	0.27
208_N	230_V	0.680	0.27
342_N	352_G	0.680	0.27
216_K	237_E	0.678	0.27
539_D	555_T	0.677	0.27
443_L	447_V	0.677	0.27
258_P	446_F	0.675	0.27
100_V	208_N	0.673	0.27
344_F	350_F	0.672	0.27
42_Q	619_V	0.672	0.27
3_I	7_L	0.671	0.27
304_H	372_I	0.670	0.27
175_V	232_A	0.669	0.27
312_M	316_V	0.668	0.27
105_A	108_G	0.667	0.27
307_S	311_N	0.666	0.27
466_L	470_N	0.663	0.26
92_L	100_V	0.662	0.26
210_S	393_A	0.662	0.26
482_M	518_M	0.660	0.26
264_K	317_V	0.660	0.26
455_F	462_W	0.659	0.26
23_N	128_E	0.659	0.26
216_K	453_A	0.658	0.26
387_M	445_Q	0.657	0.26
338_D	341_Y	0.657	0.26
208_N	238_M	0.656	0.26
387_M	446_F	0.656	0.26
496_T	549_M	0.655	0.26
148_Q	155_E	0.655	0.26
367_F	463_L	0.655	0.26
172_I	265_A	0.655	0.26
343_T	352_G	0.654	0.26
340_S	349_N	0.653	0.26
102_M	614_I	0.653	0.26
346_A	352_G	0.652	0.26
359_L	383_V	0.651	0.26
331_I	335_D	0.651	0.26
44_Y	48_I	0.651	0.26
427_K	432_Y	0.650	0.26
516_G	580_A	0.649	0.26
46_E	220_Q	0.649	0.26
359_L	513_I	0.648	0.26
464_E	468_T	0.648	0.26
399_L	480_G	0.647	0.26
466_L	472_V	0.647	0.26
336_P	341_Y	0.646	0.26
42_Q	536_T	0.645	0.25
10_H	242_K	0.645	0.25
38_L	74_I	0.644	0.25
68_A	208_N	0.644	0.25
514_M	518_M	0.644	0.25
327_F	593_A	0.643	0.25
156_E	165_A	0.642	0.25
316_V	593_A	0.642	0.25
48_I	89_Y	0.642	0.25
573_A	577_A	0.642	0.25
44_Y	232_A	0.642	0.25
293_S	455_F	0.641	0.25
341_Y	350_F	0.641	0.25
58_G	65_I	0.640	0.25
580_A	584_T	0.640	0.25
98_H	130_R	0.640	0.25
139_E	142_I	0.640	0.25
355_N	358_K	0.640	0.25
59_I	399_L	0.639	0.25
379_A	501_M	0.639	0.25
539_D	543_G	0.639	0.25
507_Y	591_L	0.638	0.25
500_A	506_N	0.637	0.25
328_F	456_M	0.637	0.25
61_E	127_E	0.637	0.25
78_I	106_T	0.636	0.25
502_I	505_G	0.635	0.25
79_A	118_S	0.634	0.25
495_F	499_I	0.633	0.25
29_V	38_L	0.632	0.25
191_A	615_V	0.632	0.25
76_P	112_T	0.631	0.25
37_K	77_A	0.631	0.25
490_L	572_A	0.630	0.25
462_W	477_I	0.630	0.25
18_S	81_G	0.629	0.25
404_L	490_L	0.629	0.25
465_S	469_G	0.629	0.25
58_G	97_A	0.628	0.25
341_Y	351_I	0.628	0.25
381_G	385_G	0.627	0.25
325_I	588_R	0.626	0.24
118_S	429_V	0.626	0.24
87_V	277_G	0.626	0.24
479_G	509_P	0.625	0.24
412_L	431_I	0.625	0.24
190_D	346_A	0.625	0.24
468_T	471_L	0.625	0.24
170_G	202_E	0.624	0.24
20_E	30_T	0.624	0.24
444_M	527_A	0.624	0.24
28_M	65_I	0.624	0.24
322_L	613_S	0.624	0.24
175_V	230_V	0.624	0.24
191_A	194_E	0.623	0.24
233_D	374_D	0.622	0.24
204_K	228_I	0.621	0.24
459_L	462_W	0.621	0.24
583_L	586_F	0.621	0.24
296_G	299_N	0.621	0.24
372_I	407_Y	0.620	0.24
173_L	471_L	0.619	0.24
173_L	204_K	0.618	0.24
546_C	625_L	0.618	0.24
330_G	339_P	0.618	0.24
443_L	452_V	0.617	0.24
360_I	584_T	0.616	0.24
296_G	300_T	0.616	0.24
172_I	259_Q	0.615	0.24
132_Q	135_E	0.615	0.24
574_V	612_L	0.615	0.24
33_D	42_Q	0.615	0.24
281_A	627_I	0.614	0.24
144_D	147_N	0.614	0.24
378_F	449_N	0.613	0.24
132_Q	280_S	0.613	0.24
387_M	549_M	0.613	0.24
191_A	255_I	0.611	0.24
404_L	408_V	0.610	0.24
253_A	258_P	0.610	0.24
511_A	514_M	0.609	0.24
199_L	267_N	0.609	0.24
193_K	203_I	0.609	0.24
128_E	134_L	0.608	0.24
327_F	553_F	0.608	0.24
98_H	131_K	0.608	0.24
312_M	357_L	0.607	0.24
129_I	149_H	0.607	0.24
230_V	238_M	0.606	0.23
70_T	121_S	0.606	0.23
341_Y	352_G	0.605	0.23
199_L	223_E	0.605	0.23
465_S	468_T	0.604	0.23
517_G	581_G	0.604	0.23
331_I	345_A	0.602	0.23
141_A	408_V	0.601	0.23
193_K	196_A	0.601	0.23
450_T	495_F	0.600	0.23
501_M	621_M	0.600	0.23
6_L	232_A	0.599	0.23
27_E	81_G	0.599	0.23
23_N	34_K	0.599	0.23
343_T	347_A	0.597	0.23
501_M	523_G	0.597	0.23
361_V	380_P	0.597	0.23
309_V	499_I	0.597	0.23
127_E	198_E	0.595	0.23
19_K	283_S	0.595	0.23
58_G	451_P	0.594	0.23
331_I	342_N	0.593	0.23
21_K	90_E	0.593	0.23
102_M	111_N	0.593	0.23
43_A	466_L	0.593	0.23
248_Q	295_S	0.592	0.23
451_P	500_A	0.592	0.23
301_F	567_L	0.592	0.23
227_A	267_N	0.592	0.23
47_A	141_A	0.592	0.23
145_I	605_N	0.589	0.23
190_D	393_A	0.589	0.23
17_E	84_K	0.587	0.23
10_H	156_E	0.586	0.22
191_A	195_K	0.586	0.22
317_V	331_I	0.585	0.22
32_L	78_I	0.585	0.22
340_S	353_G	0.585	0.22
202_E	224_D	0.584	0.22
168_G	226_P	0.584	0.22
144_D	164_P	0.582	0.22
306_M	436_G	0.582	0.22
173_L	478_L	0.582	0.22
102_M	208_N	0.582	0.22
466_L	477_I	0.581	0.22
3_I	11_T	0.581	0.22
428_P	434_L	0.580	0.22
425_G	552_A	0.580	0.22
330_G	341_Y	0.580	0.22
519_V	618_A	0.580	0.22
82_R	142_I	0.579	0.22
340_S	345_A	0.578	0.22
421_Q	623_I	0.578	0.22
50_N	145_I	0.577	0.22
484_I	516_G	0.577	0.22
170_G	224_D	0.577	0.22
518_M	581_G	0.577	0.22
359_L	379_A	0.576	0.22
588_R	622_A	0.575	0.22
380_P	437_I	0.575	0.22
530_I	626_G	0.573	0.22
312_M	315_F	0.573	0.22
360_I	363_V	0.572	0.22
304_H	486_M	0.572	0.22
85_D	615_V	0.572	0.22
128_E	198_E	0.572	0.22
567_L	571_P	0.571	0.22
22_E	163_A	0.571	0.22
340_S	347_A	0.571	0.22
415_V	583_L	0.570	0.22
202_E	228_I	0.570	0.22
34_K	141_A	0.569	0.22
591_L	604_T	0.569	0.22
6_L	204_K	0.567	0.22
140_D	505_G	0.567	0.22
155_E	165_A	0.567	0.22
56_S	381_G	0.567	0.22
434_L	513_I	0.566	0.22
506_N	509_P	0.565	0.21
327_F	517_G	0.564	0.21
151_K	154_D	0.563	0.21
172_I	254_G	0.563	0.21
257_R	264_K	0.563	0.21
366_G	613_S	0.560	0.21
573_A	624_I	0.560	0.21
48_I	193_K	0.559	0.21
428_P	546_C	0.559	0.21
38_L	115_E	0.559	0.21
518_M	599_F	0.558	0.21
420_P	423_L	0.557	0.21
572_A	578_A	0.557	0.21
545_T	561_F	0.557	0.21
36_G	192_L	0.556	0.21
392_N	585_E	0.556	0.21
472_V	476_I	0.556	0.21
422_S	429_V	0.555	0.21
431_I	454_A	0.555	0.21
198_E	270_A	0.555	0.21
32_L	58_G	0.555	0.21
495_F	517_G	0.555	0.21
132_Q	435_F	0.555	0.21
260_E	387_M	0.554	0.21
23_N	85_D	0.554	0.21
423_L	552_A	0.554	0.21
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408_V	513_I	0.552	0.21
377_G	478_L	0.551	0.21
576_G	617_G	0.550	0.21
247_L	263_E	0.550	0.21
145_I	150_D	0.550	0.21
221_E	224_D	0.550	0.21
238_M	248_Q	0.550	0.21
250_P	256_R	0.550	0.21
340_S	350_F	0.549	0.21
265_A	475_G	0.549	0.21
124_L	130_R	0.549	0.21
40_D	530_I	0.549	0.21
497_F	501_M	0.547	0.21
294_G	615_V	0.547	0.21
139_E	197_K	0.547	0.21
464_E	474_M	0.547	0.21
81_G	109_A	0.546	0.21
11_T	81_G	0.546	0.21
535_F	561_F	0.545	0.21
316_V	327_F	0.545	0.21
122_T	265_A	0.544	0.20
254_G	524_I	0.544	0.20
77_A	83_S	0.543	0.20
12_I	59_I	0.543	0.20
219_A	613_S	0.543	0.20
461_N	465_S	0.542	0.20
549_M	601_A	0.542	0.20
10_H	17_E	0.542	0.20
498_G	549_M	0.541	0.20
107_E	110_N	0.541	0.20
28_M	81_G	0.541	0.20
232_A	261_L	0.541	0.20
265_A	272_I	0.541	0.20
199_L	266_M	0.541	0.20
530_I	623_I	0.540	0.20
365_A	384_G	0.540	0.20
331_I	382_M	0.538	0.20
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358_K	499_I	0.538	0.20
460_T	467_G	0.538	0.20
226_P	266_M	0.537	0.20
378_F	460_T	0.537	0.20
321_I	531_F	0.537	0.20
531_F	630_K	0.536	0.20
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42_Q	293_S	0.536	0.20
301_F	490_L	0.536	0.20
175_V	273_Y	0.536	0.20
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359_L	509_P	0.534	0.20
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483_A	621_M	0.534	0.20
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172_I	262_I	0.533	0.20
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610_Y	614_I	0.532	0.20
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258_P	265_A	0.531	0.20
311_N	376_P	0.530	0.20
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197_K	203_I	0.526	0.20
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353_G	511_A	0.526	0.20
371_S	626_G	0.525	0.20
343_T	349_N	0.525	0.20
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571_P	574_V	0.520	0.19
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622_A	626_G	0.517	0.19
584_T	592_P	0.516	0.19
196_A	392_N	0.516	0.19
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553_F	595_H	0.511	0.19
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537_Q	579_V	0.509	0.19
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135_E	163_A	0.507	0.19
11_T	32_L	0.507	0.19
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207_T	356_A	0.506	0.19
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224_D	611_L	0.504	0.19
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446_F	509_P	0.502	0.19
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344_F	351_I	0.502	0.19
23_N	144_D	0.502	0.19
236_V	412_L	0.502	0.19
152_D	162_A	0.501	0.19
44_Y	49_L	0.501	0.19
42_Q	110_N	0.501	0.19
115_E	237_E	0.501	0.19
589_V	605_N	0.501	0.19
516_G	574_V	0.500	0.19
232_A	249_V	0.500	0.19
522_L	529_T	0.500	0.19

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2r48A	1	0.1654	100	0.839	Contact Map
1a6jA	4	0.2331	100	0.857	Contact Map
3qnqA	2	0.5496	100	0.857	Contact Map
2a0jA	1	0.2299	100	0.859	Contact Map
3urrA	2	0.2362	100	0.86	Contact Map
1a3aA	2	0.2252	100	0.864	Contact Map
2oq3A	1	0.2268	100	0.866	Contact Map
3oxpA	2	0.2283	100	0.869	Contact Map
3bjvA	2	0.2378	100	0.869	Contact Map
2r4qA	1	0.1606	100	0.87	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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