GREMLIN Database
PTF3A - PTS system fructose-specific EIIABC component
UniProt: P71012 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 635 (616)
Sequences: 983 (580)
Seq/√Len: 23.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
173_L228_I5.9261.00
527_A535_F5.4261.00
523_G621_M5.2861.00
515_A614_I4.8661.00
484_I490_L4.6311.00
373_A377_G4.3891.00
529_T547_Y4.2471.00
227_A265_A4.2121.00
259_Q263_E4.1991.00
199_L263_E4.1511.00
384_G401_A4.0981.00
213_I216_K4.0931.00
408_V439_I3.9391.00
196_A203_I3.9211.00
199_L259_Q3.7891.00
9_K140_D3.7821.00
220_Q224_D3.7281.00
174_A205_V3.7041.00
201_V262_I3.6931.00
361_V398_G3.6441.00
528_T543_G3.6111.00
242_K274_Q3.5301.00
71_A107_E3.4861.00
257_R260_E3.2551.00
91_S97_A3.2411.00
359_L386_F3.2181.00
195_K198_E3.1831.00
20_E23_N3.1801.00
590_T605_N3.1561.00
171_K224_D3.1051.00
219_A223_E3.0721.00
30_T41_R2.9821.00
26_D45_K2.9020.99
575_V624_I2.8840.99
326_S350_F2.8550.99
198_E259_Q2.7860.99
263_E267_N2.7830.99
480_G574_V2.7600.99
171_K226_P2.7040.99
612_L616_I2.6830.99
33_D38_L2.6770.99
379_A437_I2.6500.99
47_A70_T2.5000.98
496_T499_I2.4920.98
253_A257_R2.4440.98
304_H371_S2.4230.98
48_I102_M2.3890.98
204_K221_E2.3840.98
311_N378_F2.3470.98
29_V45_K2.3410.98
245_R268_Q2.3090.97
583_L587_F2.2210.97
480_G578_A2.1990.96
264_K269_D2.1960.96
524_I625_L2.1710.96
515_A580_A2.1600.96
533_N631_P2.1300.96
98_H134_L2.1270.96
367_F370_M2.1190.96
242_K275_G2.1160.95
455_F458_F2.1020.95
609_L612_L2.0890.95
227_A247_L2.0870.95
483_A577_A2.0750.95
137_E141_A2.0570.95
349_N352_G2.0540.95
138_S141_A2.0530.95
42_Q46_E2.0180.94
537_Q540_R1.9960.94
170_G226_P1.9900.94
569_V625_L1.9650.93
18_S24_V1.9570.93
369_A405_A1.9560.93
409_V436_G1.9210.92
346_A350_F1.9120.92
363_V382_M1.8980.92
169_K202_E1.8920.92
195_K259_Q1.8630.91
190_D193_K1.8500.91
484_I574_V1.8330.91
535_F626_G1.8180.90
435_F439_I1.8140.90
195_K199_L1.7990.90
97_A100_V1.7980.90
315_F382_M1.7460.88
537_Q541_E1.7350.88
587_F609_L1.7220.88
527_A626_G1.7170.87
50_N54_Q1.6970.87
130_R134_L1.6920.87
199_L262_I1.6890.86
172_I201_V1.6720.86
40_D43_A1.6500.85
25_I89_Y1.6500.85
541_E544_I1.6380.85
530_I547_Y1.6330.85
396_L400_I1.6330.85
264_K267_N1.6230.84
131_K135_E1.6160.84
126_R149_H1.6090.84
369_A381_G1.5980.83
206_E240_R1.5960.83
331_I334_A1.5850.83
132_Q148_Q1.5790.82
118_S122_T1.5740.82
458_F462_W1.5650.82
534_K626_G1.5580.82
480_G516_G1.5540.81
318_G437_I1.5470.81
495_F510_H1.5440.81
144_D148_Q1.5430.81
80_F142_I1.5370.81
381_G405_A1.5340.81
193_K197_K1.5290.80
245_R272_I1.5280.80
127_E131_K1.5190.80
336_P342_N1.5160.80
365_A401_A1.5120.80
609_L616_I1.5090.79
50_N53_S1.5080.79
619_V622_A1.5020.79
460_T464_E1.4970.79
613_S616_I1.4950.79
192_L203_I1.4930.79
13_K27_E1.4810.78
458_F461_N1.4660.77
478_L509_P1.4640.77
297_I300_T1.4580.77
589_V609_L1.4570.77
570_I574_V1.4520.77
345_A352_G1.4450.76
565_D568_R1.4450.76
30_T34_K1.4430.76
262_I266_M1.4400.76
483_A520_P1.4400.76
524_I546_C1.4390.76
349_N353_G1.4370.76
8_T37_K1.4310.76
531_F626_G1.4240.75
358_K386_F1.4190.75
534_K631_P1.4140.75
457_N461_N1.4100.74
507_Y592_P1.3960.74
616_I620_V1.3960.74
24_V83_S1.3890.73
583_L613_S1.3850.73
483_A555_T1.3740.73
232_A248_Q1.3710.72
530_I618_A1.3640.72
16_I27_E1.3630.72
373_A410_I1.3520.71
454_A458_F1.3500.71
579_V620_V1.3490.71
500_A503_D1.3490.71
523_G573_A1.3490.71
618_A622_A1.3430.71
83_S98_H1.3410.71
302_Y306_M1.3230.70
16_I81_G1.3200.69
177_A234_K1.3140.69
623_I627_I1.3140.69
249_V261_L1.3130.69
579_V616_I1.3110.69
173_L221_E1.2990.68
355_N387_M1.2970.68
18_S27_E1.2940.68
575_V616_I1.2910.68
409_V412_L1.2850.67
15_N82_R1.2740.67
25_I45_K1.2670.66
251_V254_G1.2670.66
340_S352_G1.2640.66
114_L125_M1.2580.66
171_K202_E1.2570.66
170_G266_M1.2520.65
26_D29_V1.2520.65
114_L121_S1.2430.65
611_L615_V1.2410.65
14_L82_R1.2410.65
384_G440_T1.2320.64
118_S211_S1.2310.64
22_E49_L1.2270.64
323_V357_L1.2230.63
571_P628_V1.2220.63
254_G257_R1.2220.63
11_T35_A1.2200.63
371_S423_L1.2150.63
254_G260_E1.2090.62
207_T215_H1.2080.62
174_A232_A1.2060.62
525_A529_T1.2060.62
573_A621_M1.2010.62
239_E275_G1.1970.62
182_I425_G1.1960.62
23_N26_D1.1950.62
345_A349_N1.1930.61
476_I582_G1.1890.61
32_L44_Y1.1880.61
333_S342_N1.1850.61
583_L616_I1.1800.61
125_M145_I1.1790.60
210_S428_P1.1780.60
400_I404_L1.1770.60
526_L618_A1.1740.60
217_L222_I1.1730.60
223_E226_P1.1710.60
59_I114_L1.1670.60
127_E130_R1.1590.59
62_G98_H1.1590.59
227_A258_P1.1510.59
476_I479_G1.1470.58
119_R154_D1.1460.58
498_G513_I1.1440.58
341_Y345_A1.1430.58
69_K110_N1.1410.58
29_V48_I1.1410.58
115_E118_S1.1380.58
43_A46_E1.1360.58
522_L618_A1.1360.58
123_L149_H1.1350.57
227_A262_I1.1180.56
356_A383_V1.1170.56
514_M553_F1.1130.56
387_M449_N1.1120.56
31_V34_K1.1070.56
47_A68_A1.1070.56
307_S370_M1.1070.56
49_L53_S1.1060.55
258_P262_I1.1040.55
604_T610_Y1.1020.55
624_I628_V1.1020.55
479_G610_Y1.1010.55
582_G586_F1.0990.55
344_F352_G1.0980.55
19_K23_N1.0960.55
398_G470_N1.0930.55
517_G553_F1.0900.54
46_E53_S1.0900.54
114_L124_L1.0860.54
249_V253_A1.0850.54
530_I622_A1.0800.54
382_M386_F1.0780.54
572_A628_V1.0690.53
434_L438_F1.0650.53
92_L96_P1.0630.52
174_A203_I1.0610.52
194_E538_R1.0600.52
552_A599_F1.0580.52
462_W465_S1.0580.52
76_P106_T1.0560.52
16_I83_S1.0560.52
265_A269_D1.0520.52
393_A397_G1.0510.52
8_T75_N1.0480.51
398_G506_N1.0470.51
499_I510_H1.0470.51
495_F502_I1.0430.51
58_G92_L1.0390.51
350_F354_D1.0390.51
115_E214_K1.0380.51
15_N84_K1.0380.51
39_N74_I1.0370.51
365_A369_A1.0360.51
369_A377_G1.0330.50
508_A585_E1.0310.50
525_A547_Y1.0220.50
210_S375_R1.0200.49
58_G91_S1.0190.49
601_A604_T1.0170.49
348_L352_G1.0170.49
325_I328_F1.0150.49
175_V208_N1.0090.49
127_E194_E1.0090.49
33_D41_R1.0050.48
32_L48_I1.0050.48
238_M273_Y1.0030.48
438_F442_V1.0030.48
227_A269_D1.0010.48
478_L621_M1.0010.48
172_I266_M0.9970.48
194_E197_K0.9950.48
300_T304_H0.9940.48
128_E132_Q0.9940.48
210_S429_V0.9900.47
173_L217_L0.9890.47
297_I407_Y0.9850.47
171_K221_E0.9830.47
482_M514_M0.9820.47
220_Q223_E0.9780.47
47_A50_N0.9780.47
456_M493_A0.9760.46
77_A81_G0.9730.46
367_F453_A0.9720.46
61_E95_Q0.9680.46
601_A607_P0.9660.46
330_G340_S0.9600.45
584_T589_V0.9600.45
295_S299_N0.9590.45
298_G325_I0.9580.45
367_F378_F0.9570.45
586_F613_S0.9570.45
451_P455_F0.9570.45
22_E30_T0.9560.45
582_G585_E0.9550.45
333_S336_P0.9470.44
10_H35_A0.9460.44
572_A624_I0.9410.44
140_D144_D0.9390.44
419_I427_K0.9380.44
348_L446_F0.9370.44
65_I121_S0.9330.43
23_N172_I0.9320.43
331_I336_P0.9310.43
495_F518_M0.9300.43
13_K31_V0.9280.43
514_M517_G0.9270.43
19_K138_S0.9250.43
482_M553_F0.9250.43
195_K258_P0.9230.43
234_K428_P0.9200.43
317_V542_A0.9190.42
172_I196_A0.9180.42
480_G484_I0.9170.42
344_F438_F0.9170.42
110_N116_A0.9150.42
412_L436_G0.9140.42
189_A193_K0.9140.42
499_I506_N0.9120.42
260_E264_K0.9100.42
151_K155_E0.9070.42
344_F349_N0.9070.42
171_K203_I0.9070.42
399_L500_A0.9050.41
50_N91_S0.9050.41
332_H336_P0.9030.41
272_I574_V0.9030.41
486_M555_T0.9010.41
338_D342_N0.9010.41
96_P305_L0.9000.41
18_S83_S0.8980.41
172_I203_I0.8950.41
84_K135_E0.8950.41
140_D624_I0.8940.41
536_T539_D0.8930.41
419_I431_I0.8900.40
551_A611_L0.8890.40
128_E131_K0.8880.40
195_K263_E0.8880.40
141_A145_I0.8880.40
102_M109_A0.8840.40
168_G224_D0.8830.40
68_A110_N0.8820.40
325_I349_N0.8810.40
29_V49_L0.8800.40
378_F381_G0.8780.40
140_D220_Q0.8780.40
201_V266_M0.8760.40
482_M517_G0.8720.39
498_G504_A0.8700.39
346_A349_N0.8700.39
352_G509_P0.8690.39
486_M580_A0.8600.38
83_S100_V0.8550.38
175_V238_M0.8550.38
334_A337_N0.8550.38
317_V544_I0.8510.38
340_S344_F0.8500.38
177_A232_A0.8490.38
519_V580_A0.8480.38
511_A518_M0.8470.38
456_M546_C0.8440.37
510_H513_I0.8430.37
61_E130_R0.8410.37
65_I125_M0.8390.37
28_M79_A0.8360.37
194_E198_E0.8360.37
27_E83_S0.8360.37
520_P577_A0.8340.37
43_A71_A0.8320.37
343_T346_A0.8310.37
591_L610_Y0.8300.36
293_S296_G0.8280.36
313_L427_K0.8270.36
424_D427_K0.8250.36
526_L622_A0.8240.36
38_L41_R0.8240.36
508_A584_T0.8230.36
174_A201_V0.8220.36
439_I443_L0.8220.36
38_L72_S0.8220.36
218_T221_E0.8210.36
65_I82_R0.8210.36
297_I301_F0.8190.36
328_F598_V0.8180.36
109_A112_T0.8180.36
43_A72_S0.8160.36
499_I503_D0.8160.36
12_I46_E0.8150.36
90_E97_A0.8130.35
6_L118_S0.8120.35
518_M553_F0.8120.35
475_G479_G0.8110.35
169_K224_D0.8100.35
175_V365_A0.8100.35
145_I149_H0.8080.35
479_G515_A0.8070.35
552_A593_A0.8070.35
58_G121_S0.8020.35
495_F584_T0.8020.35
366_G382_M0.8010.35
12_I189_A0.8010.35
329_W332_H0.8010.35
102_M118_S0.8000.35
119_R408_V0.7990.35
526_L529_T0.7980.34
574_V577_A0.7970.34
583_L609_L0.7970.34
89_Y256_R0.7970.34
47_A121_S0.7960.34
111_N121_S0.7950.34
411_L484_I0.7950.34
105_A109_A0.7940.34
309_V316_V0.7920.34
476_I578_A0.7910.34
367_F413_K0.7890.34
471_L508_A0.7840.34
456_M524_I0.7830.33
455_F480_G0.7820.33
17_E23_N0.7810.33
429_V434_L0.7800.33
16_I28_M0.7760.33
173_L506_N0.7750.33
76_P107_E0.7750.33
522_L551_A0.7720.33
32_L77_A0.7690.33
14_L139_E0.7680.33
408_V411_L0.7680.33
306_M496_T0.7660.32
472_V586_F0.7660.32
360_I378_F0.7660.32
164_P281_A0.7650.32
502_I510_H0.7640.32
335_D342_N0.7640.32
58_G82_R0.7610.32
37_K75_N0.7610.32
411_L415_V0.7610.32
227_A268_Q0.7600.32
22_E53_S0.7600.32
476_I620_V0.7590.32
127_E145_I0.7570.32
330_G398_G0.7570.32
606_H609_L0.7540.32
81_G87_V0.7530.32
531_F534_K0.7520.32
253_A264_K0.7520.32
344_F348_L0.7510.32
452_V493_A0.7510.32
201_V455_F0.7510.32
48_I100_V0.7510.32
355_N445_Q0.7500.31
46_E50_N0.7490.31
451_P561_F0.7490.31
72_S259_Q0.7490.31
459_L477_I0.7480.31
478_L513_I0.7480.31
45_K49_L0.7470.31
239_E242_K0.7460.31
26_D48_I0.7460.31
23_N27_E0.7460.31
26_D49_L0.7450.31
467_G586_F0.7450.31
203_I262_I0.7420.31
22_E26_D0.7420.31
602_F605_N0.7410.31
472_V611_L0.7400.31
45_K89_Y0.7400.31
565_D629_K0.7380.31
195_K498_G0.7370.31
165_A282_A0.7340.31
455_F548_F0.7340.31
441_G444_M0.7330.30
193_K258_P0.7330.30
136_A325_I0.7320.30
6_L179_P0.7320.30
359_L382_M0.7310.30
332_H335_D0.7300.30
345_A351_I0.7300.30
162_A166_P0.7290.30
26_D30_T0.7280.30
366_G439_I0.7280.30
507_Y590_T0.7270.30
480_G577_A0.7270.30
87_V100_V0.7240.30
8_T455_F0.7220.30
538_R541_E0.7220.30
451_P454_A0.7200.30
22_E90_E0.7200.30
175_V237_E0.7200.30
115_E211_S0.7170.30
511_A517_G0.7170.30
230_V269_D0.7160.29
129_I146_I0.7150.29
305_L403_F0.7140.29
61_E121_S0.7110.29
627_I631_P0.7100.29
12_I143_I0.7080.29
425_G525_A0.7070.29
72_S195_K0.7070.29
502_I604_T0.7070.29
518_M594_P0.7060.29
196_A205_V0.7060.29
19_K135_E0.7060.29
590_T613_S0.7060.29
526_L530_I0.7060.29
69_K116_A0.7040.29
528_T622_A0.7040.29
501_M564_A0.7040.29
345_A353_G0.7020.29
347_A352_G0.7020.29
360_I398_G0.7010.29
329_W334_A0.7010.29
408_V440_T0.7000.29
19_K167_A0.7000.29
452_V455_F0.6990.28
196_A483_A0.6990.28
443_L479_G0.6960.28
192_L539_D0.6950.28
502_I506_N0.6950.28
26_D223_E0.6930.28
13_K34_K0.6930.28
258_P266_M0.6930.28
28_M102_M0.6920.28
163_A167_A0.6890.28
199_L258_P0.6880.28
496_T510_H0.6820.28
412_L419_I0.6820.28
479_G516_G0.6820.28
334_A367_F0.6810.27
208_N230_V0.6800.27
342_N352_G0.6800.27
216_K237_E0.6780.27
539_D555_T0.6770.27
443_L447_V0.6770.27
258_P446_F0.6750.27
100_V208_N0.6730.27
344_F350_F0.6720.27
42_Q619_V0.6720.27
3_I7_L0.6710.27
304_H372_I0.6700.27
175_V232_A0.6690.27
312_M316_V0.6680.27
105_A108_G0.6670.27
307_S311_N0.6660.27
466_L470_N0.6630.26
92_L100_V0.6620.26
210_S393_A0.6620.26
482_M518_M0.6600.26
264_K317_V0.6600.26
455_F462_W0.6590.26
23_N128_E0.6590.26
216_K453_A0.6580.26
387_M445_Q0.6570.26
338_D341_Y0.6570.26
208_N238_M0.6560.26
387_M446_F0.6560.26
496_T549_M0.6550.26
148_Q155_E0.6550.26
367_F463_L0.6550.26
172_I265_A0.6550.26
343_T352_G0.6540.26
340_S349_N0.6530.26
102_M614_I0.6530.26
346_A352_G0.6520.26
359_L383_V0.6510.26
331_I335_D0.6510.26
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336_P341_Y0.6460.26
42_Q536_T0.6450.25
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355_N358_K0.6400.25
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379_A501_M0.6390.25
539_D543_G0.6390.25
507_Y591_L0.6380.25
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462_W477_I0.6300.25
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341_Y351_I0.6280.25
381_G385_G0.6270.25
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233_D374_D0.6220.24
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372_I407_Y0.6200.24
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450_T495_F0.6000.23
501_M621_M0.6000.23
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144_D164_P0.5820.22
306_M436_G0.5820.22
173_L478_L0.5820.22
102_M208_N0.5820.22
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3_I11_T0.5810.22
428_P434_L0.5800.22
425_G552_A0.5800.22
330_G341_Y0.5800.22
519_V618_A0.5800.22
82_R142_I0.5790.22
340_S345_A0.5780.22
421_Q623_I0.5780.22
50_N145_I0.5770.22
484_I516_G0.5770.22
170_G224_D0.5770.22
518_M581_G0.5770.22
359_L379_A0.5760.22
588_R622_A0.5750.22
380_P437_I0.5750.22
530_I626_G0.5730.22
312_M315_F0.5730.22
360_I363_V0.5720.22
304_H486_M0.5720.22
85_D615_V0.5720.22
128_E198_E0.5720.22
567_L571_P0.5710.22
22_E163_A0.5710.22
340_S347_A0.5710.22
415_V583_L0.5700.22
202_E228_I0.5700.22
34_K141_A0.5690.22
591_L604_T0.5690.22
6_L204_K0.5670.22
140_D505_G0.5670.22
155_E165_A0.5670.22
56_S381_G0.5670.22
434_L513_I0.5660.22
506_N509_P0.5650.21
327_F517_G0.5640.21
151_K154_D0.5630.21
172_I254_G0.5630.21
257_R264_K0.5630.21
366_G613_S0.5600.21
573_A624_I0.5600.21
48_I193_K0.5590.21
428_P546_C0.5590.21
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572_A578_A0.5570.21
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392_N585_E0.5560.21
472_V476_I0.5560.21
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431_I454_A0.5550.21
198_E270_A0.5550.21
32_L58_G0.5550.21
495_F517_G0.5550.21
132_Q435_F0.5550.21
260_E387_M0.5540.21
23_N85_D0.5540.21
423_L552_A0.5540.21
26_D41_R0.5540.21
452_V458_F0.5540.21
408_V513_I0.5520.21
377_G478_L0.5510.21
576_G617_G0.5500.21
247_L263_E0.5500.21
145_I150_D0.5500.21
221_E224_D0.5500.21
238_M248_Q0.5500.21
250_P256_R0.5500.21
340_S350_F0.5490.21
265_A475_G0.5490.21
124_L130_R0.5490.21
40_D530_I0.5490.21
497_F501_M0.5470.21
294_G615_V0.5470.21
139_E197_K0.5470.21
464_E474_M0.5470.21
81_G109_A0.5460.21
11_T81_G0.5460.21
535_F561_F0.5450.21
316_V327_F0.5450.21
122_T265_A0.5440.20
254_G524_I0.5440.20
77_A83_S0.5430.20
12_I59_I0.5430.20
219_A613_S0.5430.20
461_N465_S0.5420.20
549_M601_A0.5420.20
10_H17_E0.5420.20
498_G549_M0.5410.20
107_E110_N0.5410.20
28_M81_G0.5410.20
232_A261_L0.5410.20
265_A272_I0.5410.20
199_L266_M0.5410.20
530_I623_I0.5400.20
365_A384_G0.5400.20
331_I382_M0.5380.20
50_N612_L0.5380.20
358_K499_I0.5380.20
460_T467_G0.5380.20
226_P266_M0.5370.20
378_F460_T0.5370.20
321_I531_F0.5370.20
531_F630_K0.5360.20
85_D135_E0.5360.20
42_Q293_S0.5360.20
301_F490_L0.5360.20
175_V273_Y0.5360.20
96_P322_L0.5350.20
359_L509_P0.5340.20
363_V503_D0.5340.20
483_A621_M0.5340.20
76_P134_L0.5330.20
155_E281_A0.5330.20
172_I262_I0.5330.20
471_L588_R0.5330.20
610_Y614_I0.5320.20
517_G520_P0.5320.20
102_M108_G0.5320.20
304_H407_Y0.5310.20
432_Y516_G0.5310.20
258_P265_A0.5310.20
311_N376_P0.5300.20
332_H342_N0.5300.20
144_D620_V0.5280.20
396_L486_M0.5280.20
196_A262_I0.5270.20
123_L129_I0.5270.20
569_V572_A0.5260.20
197_K203_I0.5260.20
429_V501_M0.5260.20
353_G511_A0.5260.20
371_S626_G0.5250.20
343_T349_N0.5250.20
331_I341_Y0.5250.20
191_A256_R0.5240.20
504_A551_A0.5240.20
278_G281_A0.5230.20
44_Y111_N0.5220.20
293_S623_I0.5220.20
175_V254_G0.5210.19
551_A607_P0.5200.19
131_K166_P0.5200.19
571_P574_V0.5200.19
77_A108_G0.5200.19
43_A47_A0.5200.19
223_E461_N0.5180.19
235_Q303_K0.5180.19
622_A626_G0.5170.19
584_T592_P0.5160.19
196_A392_N0.5160.19
367_F497_F0.5150.19
230_V577_A0.5150.19
514_M599_F0.5140.19
577_A601_A0.5140.19
356_A478_L0.5140.19
45_K72_S0.5140.19
464_E506_N0.5140.19
219_A623_I0.5140.19
175_V247_L0.5130.19
448_V452_V0.5130.19
359_L572_A0.5120.19
129_I145_I0.5120.19
511_A553_F0.5120.19
28_M189_A0.5120.19
167_A246_V0.5110.19
553_F595_H0.5110.19
179_P375_R0.5110.19
537_Q579_V0.5090.19
572_A621_M0.5090.19
451_P509_P0.5090.19
409_V432_Y0.5090.19
360_I498_G0.5080.19
575_V620_V0.5080.19
398_G549_M0.5080.19
247_L269_D0.5080.19
208_N547_Y0.5070.19
125_M186_F0.5070.19
196_A199_L0.5070.19
309_V563_A0.5070.19
331_I377_G0.5070.19
135_E163_A0.5070.19
11_T32_L0.5070.19
180_T327_F0.5060.19
340_S343_T0.5060.19
207_T356_A0.5060.19
12_I118_S0.5060.19
375_R428_P0.5050.19
477_I537_Q0.5040.19
224_D611_L0.5040.19
410_I414_K0.5030.19
604_T607_P0.5030.19
446_F509_P0.5020.19
302_Y357_L0.5020.19
60_G121_S0.5020.19
344_F351_I0.5020.19
23_N144_D0.5020.19
236_V412_L0.5020.19
152_D162_A0.5010.19
44_Y49_L0.5010.19
42_Q110_N0.5010.19
115_E237_E0.5010.19
589_V605_N0.5010.19
516_G574_V0.5000.19
232_A249_V0.5000.19
522_L529_T0.5000.19
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2r48A 1 0.1654 100 0.839 Contact Map
1a6jA 4 0.2331 100 0.857 Contact Map
3qnqA 2 0.5496 100 0.857 Contact Map
2a0jA 1 0.2299 100 0.859 Contact Map
3urrA 2 0.2362 100 0.86 Contact Map
1a3aA 2 0.2252 100 0.864 Contact Map
2oq3A 1 0.2268 100 0.866 Contact Map
3oxpA 2 0.2283 100 0.869 Contact Map
3bjvA 2 0.2378 100 0.869 Contact Map
2r4qA 1 0.1606 100 0.87 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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