SPEB - BACSU - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

SPEB - Agmatinase

UniProt:	P70999	Sequences: MRFDEAYSGKVFIASRPEWEEADAILYGMPMDWTVSYRPGSRFGPSRIREVSIGLEEYSPYLDRDLADLNFFDAGDIPLPFGNPQRSLDMIEEYVDSILEKGKFPMGMGGEHLVSWPVIKAMYKKYPDLAIIHFDAHTDLRVDYEGEPLSHSTPIRKAAELIGPHNVYSFGIRSGMKEEFEWAKENGMHISKFEVLEPLKEVLPKLAGRPVYVTIDIDVLDPAHAPGTGTVDAGGITSKELLASVHEIARSEVNVKGADLVEVAPVYDHSEQTANTASKIIREMLLGFVK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	290 (264)
Sequences:	5206 (3335)
Seq/√Len:	205.2

ECOLI - SPEB
BACSU - SPEB HUTG ARGI
HALSA - HUTG Q9HP79
SULSO - Q97ZX8 Q97VA3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
48_I	108_M	3.952	1.00
215_I	241_L	3.702	1.00
96_D	124_K	3.660	1.00
92_E	120_K	3.232	1.00
119_I	158_A	3.195	1.00
220_L	276_T	3.097	1.00
46_S	76_D	2.874	1.00
92_E	124_K	2.851	1.00
225_A	273_T	2.622	1.00
217_I	228_T	2.497	1.00
258_A	284_M	2.309	1.00
181_E	185_E	2.273	1.00
28_G	49_R	2.217	1.00
130_A	209_R	2.124	1.00
89_D	93_E	2.057	1.00
27_Y	98_I	2.041	1.00
217_I	263_V	2.018	1.00
220_L	241_L	2.014	1.00
46_S	50_E	1.992	1.00
128_D	209_R	1.963	1.00
238_S	276_T	1.940	1.00
25_I	103_K	1.904	1.00
213_V	255_V	1.885	1.00
99_L	121_A	1.872	1.00
92_E	121_A	1.863	1.00
169_S	172_I	1.861	1.00
116_W	120_K	1.833	1.00
86_R	90_M	1.823	1.00
134_F	244_S	1.822	1.00
95_V	118_V	1.820	1.00
189_H	205_K	1.820	1.00
156_R	160_E	1.779	1.00
260_L	281_I	1.764	1.00
95_V	107_G	1.760	1.00
134_F	219_V	1.758	1.00
29_M	107_G	1.749	1.00
100_E	125_K	1.738	1.00
32_D	42_R	1.727	1.00
29_M	91_I	1.721	1.00
96_D	100_E	1.717	1.00
108_M	281_I	1.713	1.00
200_K	204_P	1.692	1.00
197_E	239_K	1.647	1.00
168_Y	189_H	1.642	1.00
107_G	118_V	1.632	1.00
219_V	236_I	1.627	1.00
106_M	258_A	1.608	1.00
48_I	277_A	1.604	1.00
182_W	186_N	1.598	1.00
25_I	98_I	1.560	1.00
263_V	277_A	1.547	1.00
29_M	87_S	1.503	1.00
212_Y	257_G	1.489	1.00
217_I	260_L	1.485	1.00
172_I	190_I	1.484	1.00
122_M	129_L	1.471	1.00
224_H	238_S	1.467	1.00
189_H	201_E	1.467	1.00
237_T	240_E	1.466	1.00
210_P	254_N	1.457	1.00
219_V	241_L	1.444	1.00
200_K	247_E	1.439	1.00
99_L	125_K	1.434	1.00
263_V	273_T	1.418	1.00
23_D	70_N	1.416	1.00
114_V	261_V	1.414	1.00
128_D	166_N	1.403	1.00
217_I	225_A	1.396	1.00
92_E	96_D	1.394	1.00
166_N	209_R	1.394	1.00
88_L	113_L	1.367	1.00
48_I	263_V	1.363	1.00
246_H	283_E	1.363	1.00
24_A	285_L	1.362	1.00
47_R	274_A	1.356	1.00
99_L	122_M	1.354	1.00
83_N	86_R	1.352	1.00
132_I	248_I	1.313	1.00
192_K	195_V	1.312	1.00
133_H	169_S	1.308	1.00
49_R	76_D	1.304	1.00
151_H	230_T	1.303	1.00
25_I	74_A	1.301	1.00
27_Y	107_G	1.287	1.00
38_R	267_Y	1.281	1.00
193_F	197_E	1.279	1.00
202_V	205_K	1.278	1.00
227_G	273_T	1.275	1.00
47_R	50_E	1.264	1.00
106_M	281_I	1.260	1.00
197_E	240_E	1.260	1.00
156_R	182_W	1.255	1.00
126_Y	256_K	1.252	1.00
227_G	268_D	1.243	1.00
94_Y	97_S	1.236	1.00
213_V	258_A	1.233	1.00
198_P	243_A	1.222	1.00
27_Y	95_V	1.215	1.00
112_H	214_T	1.213	1.00
201_E	205_K	1.208	1.00
151_H	229_G	1.201	1.00
98_I	105_P	1.191	1.00
142_V	157_K	1.188	1.00
157_K	160_E	1.186	1.00
28_G	75_G	1.180	1.00
242_L	283_E	1.174	1.00
43_F	266_V	1.160	1.00
121_A	125_K	1.154	1.00
204_P	207_A	1.149	1.00
28_G	76_D	1.145	1.00
138_T	175_G	1.141	1.00
131_I	155_I	1.138	1.00
217_I	277_A	1.128	1.00
118_V	259_D	1.127	1.00
35_V	41_S	1.126	1.00
49_R	73_D	1.125	1.00
39_P	43_F	1.122	1.00
49_R	75_G	1.122	1.00
95_V	105_P	1.121	1.00
80_P	84_P	1.115	1.00
155_I	169_S	1.111	1.00
96_D	121_A	1.105	1.00
91_I	107_G	1.098	1.00
150_S	153_T	1.089	1.00
236_I	244_S	1.071	1.00
96_D	125_K	1.071	1.00
88_L	117_P	1.067	1.00
26_L	108_M	1.067	1.00
203_L	207_A	1.064	1.00
87_S	91_I	1.062	1.00
93_E	97_S	1.061	1.00
86_R	89_D	1.057	1.00
28_G	73_D	1.056	1.00
225_A	276_T	1.054	1.00
24_A	104_F	1.053	1.00
135_D	139_D	1.053	1.00
137_H	218_D	1.050	1.00
118_V	212_Y	1.049	1.00
210_P	256_K	1.040	1.00
126_Y	210_P	1.036	1.00
29_M	114_V	1.021	1.00
79_L	87_S	1.017	1.00
27_Y	94_Y	1.015	1.00
264_A	267_Y	1.014	1.00
140_L	183_A	1.006	1.00
104_F	258_A	0.992	1.00
97_S	100_E	0.987	1.00
202_V	206_L	0.985	1.00
115_S	119_I	0.982	1.00
133_H	214_T	0.976	1.00
197_E	243_A	0.974	1.00
241_L	280_I	0.959	0.99
213_V	245_V	0.948	0.99
155_I	167_V	0.943	0.99
39_P	42_R	0.941	0.99
134_F	236_I	0.941	0.99
151_H	228_T	0.939	0.99
142_V	156_R	0.933	0.99
73_D	76_D	0.912	0.99
130_A	166_N	0.911	0.99
41_S	264_A	0.908	0.99
191_S	196_L	0.907	0.99
122_M	257_G	0.906	0.99
129_L	256_K	0.902	0.99
138_T	169_S	0.898	0.99
168_Y	205_K	0.897	0.99
273_T	277_A	0.897	0.99
95_V	121_A	0.896	0.99
170_F	202_V	0.896	0.99
215_I	280_I	0.890	0.99
183_A	188_M	0.889	0.99
138_T	172_I	0.889	0.99
119_I	131_I	0.885	0.99
24_A	69_L	0.883	0.99
32_D	40_G	0.879	0.99
152_S	230_T	0.877	0.99
173_R	222_P	0.876	0.99
115_S	259_D	0.873	0.99
269_H	272_Q	0.872	0.99
173_R	221_D	0.868	0.99
128_D	163_G	0.866	0.99
220_L	238_S	0.866	0.99
23_D	103_K	0.863	0.99
47_R	51_V	0.863	0.99
131_I	158_A	0.862	0.99
194_E	243_A	0.861	0.99
136_A	173_R	0.859	0.99
191_S	195_V	0.858	0.99
115_S	154_P	0.850	0.99
151_H	262_E	0.848	0.99
81_F	84_P	0.848	0.99
140_L	159_A	0.848	0.99
98_I	103_K	0.844	0.99
138_T	190_I	0.840	0.99
162_I	167_V	0.840	0.99
112_H	151_H	0.835	0.99
141_R	179_E	0.834	0.99
112_H	262_E	0.828	0.98
130_A	168_Y	0.825	0.98
228_T	231_V	0.820	0.98
211_V	254_N	0.814	0.98
184_K	190_I	0.814	0.98
112_H	259_D	0.813	0.98
265_P	268_D	0.809	0.98
244_S	247_E	0.809	0.98
74_A	98_I	0.808	0.98
77_I	90_M	0.807	0.98
272_Q	276_T	0.806	0.98
58_Y	63_D	0.805	0.98
194_E	246_H	0.804	0.98
32_D	38_R	0.804	0.98
27_Y	105_P	0.803	0.98
131_I	162_I	0.800	0.98
201_E	204_P	0.798	0.98
174_S	232_D	0.795	0.98
247_E	252_E	0.792	0.98
203_L	247_E	0.789	0.98
89_D	92_E	0.784	0.98
195_V	198_P	0.783	0.98
238_S	242_L	0.782	0.98
130_A	206_L	0.779	0.98
32_D	41_S	0.779	0.98
93_E	96_D	0.769	0.98
163_G	166_N	0.769	0.98
281_I	284_M	0.766	0.98
123_Y	161_L	0.765	0.97
236_I	241_L	0.764	0.97
91_I	117_P	0.763	0.97
97_S	101_K	0.763	0.97
118_V	257_G	0.759	0.97
182_W	185_E	0.759	0.97
122_M	256_K	0.754	0.97
44_G	229_G	0.746	0.97
134_F	170_F	0.743	0.97
220_L	224_H	0.742	0.97
224_H	237_T	0.742	0.97
132_I	170_F	0.742	0.97
132_I	211_V	0.739	0.97
196_L	240_E	0.737	0.97
213_V	284_M	0.735	0.97
159_A	164_P	0.726	0.97
32_D	39_P	0.725	0.97
142_V	148_P	0.718	0.96
105_P	122_M	0.711	0.96
119_I	129_L	0.709	0.96
167_V	188_M	0.709	0.96
140_L	182_W	0.709	0.96
107_G	114_V	0.706	0.96
159_A	165_H	0.698	0.96
222_P	225_A	0.695	0.96
132_I	168_Y	0.693	0.96
139_D	262_E	0.690	0.95
113_L	149_L	0.688	0.95
36_S	151_H	0.683	0.95
143_D	157_K	0.683	0.95
191_S	205_K	0.682	0.95
212_Y	259_D	0.681	0.95
138_T	183_A	0.675	0.95
51_V	274_A	0.673	0.95
203_L	206_L	0.672	0.95
225_A	263_V	0.669	0.95
132_I	206_L	0.668	0.95
181_E	184_K	0.667	0.94
118_V	122_M	0.666	0.94
205_K	208_G	0.665	0.94
30_P	76_D	0.665	0.94
242_L	280_I	0.664	0.94
44_G	265_P	0.664	0.94
173_R	232_D	0.662	0.94
44_G	264_A	0.661	0.94
228_T	264_A	0.659	0.94
26_L	106_M	0.659	0.94
47_R	271_E	0.658	0.94
227_G	263_V	0.658	0.94
239_K	243_A	0.656	0.94
243_A	247_E	0.656	0.94
90_M	94_Y	0.655	0.94
168_Y	191_S	0.654	0.94
117_P	121_A	0.653	0.94
143_D	146_G	0.652	0.94
263_V	274_A	0.649	0.94
38_R	231_V	0.648	0.94
196_L	244_S	0.648	0.94
131_I	167_V	0.646	0.94
171_G	219_V	0.645	0.93
29_M	118_V	0.643	0.93
94_Y	98_I	0.642	0.93
34_T	111_E	0.638	0.93
271_E	274_A	0.636	0.93
44_G	47_R	0.634	0.93
115_S	155_I	0.634	0.93
129_L	210_P	0.630	0.93
170_F	236_I	0.629	0.93
47_R	265_P	0.628	0.93
24_A	106_M	0.627	0.92
203_L	208_G	0.624	0.92
177_K	181_E	0.623	0.92
73_D	77_I	0.623	0.92
106_M	285_L	0.621	0.92
33_W	87_S	0.620	0.92
31_M	87_S	0.620	0.92
258_A	281_I	0.619	0.92
183_A	190_I	0.618	0.92
223_A	238_S	0.617	0.92
199_L	244_S	0.616	0.92
74_A	94_Y	0.616	0.92
168_Y	202_V	0.616	0.92
120_K	158_A	0.615	0.92
127_P	210_P	0.615	0.92
134_F	213_V	0.611	0.92
50_E	271_E	0.610	0.91
139_D	218_D	0.609	0.91
51_V	278_S	0.608	0.91
51_V	271_E	0.607	0.91
283_E	286_L	0.607	0.91
135_D	218_D	0.606	0.91
22_A	103_K	0.603	0.91
66_L	71_F	0.601	0.91
71_F	76_D	0.598	0.91
114_V	214_T	0.596	0.90
112_H	212_Y	0.596	0.90
199_L	247_E	0.596	0.90
26_L	71_F	0.594	0.90
214_T	259_D	0.594	0.90
214_T	261_V	0.591	0.90
77_I	94_Y	0.590	0.90
112_H	137_H	0.589	0.90
109_G	114_V	0.589	0.90
90_M	93_E	0.588	0.90
48_I	278_S	0.587	0.90
159_A	167_V	0.587	0.90
207_A	254_N	0.586	0.90
140_L	186_N	0.586	0.90
191_S	201_E	0.585	0.90
133_H	155_I	0.583	0.90
203_L	252_E	0.582	0.89
268_D	271_E	0.580	0.89
159_A	188_M	0.580	0.89
234_G	242_L	0.578	0.89
209_R	254_N	0.575	0.89
123_Y	127_P	0.575	0.89
35_V	39_P	0.573	0.89
278_S	281_I	0.568	0.88
21_E	70_N	0.568	0.88
112_H	261_V	0.567	0.88
48_I	281_I	0.567	0.88
34_T	84_P	0.565	0.88
211_V	255_V	0.562	0.88
133_H	230_T	0.562	0.88
123_Y	129_L	0.557	0.87
25_I	72_F	0.556	0.87
130_A	210_P	0.554	0.87
61_Y	64_R	0.554	0.87
202_V	244_S	0.553	0.87
31_M	84_P	0.552	0.87
143_D	148_P	0.551	0.87
170_F	196_L	0.551	0.87
115_S	261_V	0.549	0.87
141_R	230_T	0.544	0.86
95_V	117_P	0.544	0.86
211_V	253_V	0.544	0.86
123_Y	166_N	0.543	0.86
243_A	246_H	0.541	0.86
133_H	154_P	0.541	0.86
145_E	152_S	0.539	0.86
128_D	210_P	0.539	0.86
33_W	84_P	0.538	0.85
138_T	180_F	0.533	0.85
260_L	280_I	0.533	0.85
226_P	273_T	0.532	0.85
59_S	283_E	0.531	0.85
33_W	36_S	0.527	0.84
87_S	90_M	0.521	0.84
268_D	273_T	0.519	0.83
138_T	174_S	0.519	0.83
115_S	212_Y	0.518	0.83
102_G	125_K	0.518	0.83
193_F	236_I	0.516	0.83
141_R	152_S	0.516	0.83
227_G	271_E	0.515	0.83
62_L	65_D	0.514	0.83
138_T	141_R	0.514	0.83
59_S	62_L	0.513	0.83
152_S	218_D	0.512	0.83
119_I	162_I	0.511	0.82
116_W	157_K	0.510	0.82
225_A	228_T	0.509	0.82
43_F	46_S	0.509	0.82
234_G	238_S	0.509	0.82
199_L	202_V	0.507	0.82
248_I	253_V	0.506	0.82
276_T	280_I	0.503	0.81
203_L	253_V	0.502	0.81
99_L	102_G	0.502	0.81
224_H	276_T	0.501	0.81
123_Y	162_I	0.500	0.81

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1gq6A	5	0.9897	100	0.133	Contact Map
1wohA	5	0.9759	100	0.134	Contact Map
3m1rA	5	0.9655	100	0.135	Contact Map
3nioA	5	0.9586	100	0.137	Contact Map
3lhlA	3	0.9379	100	0.143	Contact Map
3niqA	5	0.9862	100	0.147	Contact Map
4mykA	3	0.9276	100	0.152	Contact Map
3pzlA	5	0.9724	100	0.16	Contact Map
4dz4A	5	0.9621	100	0.161	Contact Map
1xfkA	1	0.9655	100	0.171	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0094 seconds.