GREMLIN Database
PBPG - Penicillin-binding protein 2D
UniProt: P70997 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 691 (596)
Sequences: 8552 (5855)
Seq/√Len: 239.8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
194_K203_E4.9201.00
185_E195_H4.1391.00
245_Q249_D4.0291.00
474_V576_G3.8931.00
238_E248_A3.8231.00
244_S247_K3.8161.00
567_I576_G3.4181.00
497_D501_H3.2901.00
416_I426_D3.2521.00
84_P88_K3.2191.00
331_A575_A3.2121.00
331_A603_F3.1041.00
227_K231_K3.0221.00
273_F302_T2.9151.00
485_K512_Q2.9021.00
315_I327_V2.8561.00
523_A569_F2.8541.00
238_E245_Q2.8371.00
86_I184_I2.6771.00
185_E196_A2.6131.00
99_Y165_D2.5081.00
235_R252_I2.5031.00
97_N105_D2.4831.00
334_P574_A2.4781.00
108_R111_G2.4541.00
60_S304_D2.3791.00
88_K242_M2.3591.00
163_S166_E2.3511.00
392_E403_S2.3181.00
248_A252_I2.3061.00
79_L87_V2.2701.00
378_S441_K2.2591.00
58_Y298_N2.2581.00
59_A63_S2.2361.00
329_F603_F2.2331.00
84_P87_V2.2081.00
202_A254_E2.2081.00
78_P81_D2.2061.00
333_D336_T2.1911.00
201_D243_I2.1681.00
420_Q424_L2.1601.00
419_L524_S2.1401.00
338_N490_T2.1231.00
93_I232_T2.1231.00
79_L169_E2.1051.00
339_V491_F2.1041.00
56_I64_K2.0721.00
338_N493_S2.0671.00
87_V165_D2.0551.00
83_N196_A2.0441.00
475_N489_P2.0411.00
300_Y494_R2.0261.00
206_L226_A1.9891.00
311_A329_F1.9841.00
419_L528_G1.9421.00
79_L165_D1.9331.00
85_T204_A1.9271.00
340_L573_L1.9061.00
317_E602_D1.9051.00
475_N486_K1.9031.00
96_Q236_M1.8971.00
333_D340_L1.8821.00
115_A124_Q1.8801.00
374_K445_T1.8761.00
81_D197_K1.8691.00
377_Q448_E1.8661.00
407_Y591_E1.8611.00
524_S527_T1.8601.00
85_T88_K1.8571.00
101_H159_E1.8261.00
355_R582_D1.8211.00
363_P468_V1.8201.00
470_P576_G1.8131.00
90_T208_A1.8011.00
201_D251_L1.7911.00
181_A190_L1.7591.00
213_G216_G1.7561.00
235_R248_A1.7511.00
236_M239_K1.7501.00
276_N491_F1.7471.00
480_L522_T1.7461.00
608_L611_E1.7281.00
473_M567_I1.7281.00
333_D338_N1.7171.00
483_G520_F1.7151.00
412_A426_D1.7141.00
93_I236_M1.7101.00
234_V248_A1.7041.00
370_L476_A1.7031.00
382_P521_V1.7011.00
367_I446_A1.6881.00
92_A242_M1.6741.00
86_I204_A1.6691.00
195_H198_N1.6641.00
444_K448_E1.6631.00
330_S471_I1.6591.00
434_H442_L1.6561.00
307_M607_A1.6451.00
58_Y300_Y1.6441.00
91_V99_Y1.6381.00
298_N496_T1.6311.00
330_S470_P1.6291.00
96_Q240_Q1.6291.00
376_I525_M1.6271.00
369_P480_L1.6171.00
382_P525_M1.6161.00
385_L415_P1.6101.00
90_T177_Y1.6081.00
134_A158_L1.6081.00
56_I298_N1.6051.00
236_M240_Q1.5961.00
111_G124_Q1.5781.00
309_R313_E1.5771.00
555_G566_M1.5751.00
517_K621_G1.5691.00
92_A240_Q1.5681.00
600_W604_M1.5461.00
60_S340_L1.5411.00
86_I90_T1.5281.00
554_A569_F1.5271.00
329_F575_A1.4991.00
332_I474_V1.4901.00
199_L204_A1.4891.00
601_A605_E1.4831.00
189_R193_G1.4811.00
366_T473_M1.4811.00
222_N225_K1.4791.00
90_T211_P1.4771.00
119_A123_V1.4751.00
273_F303_V1.4741.00
307_M340_L1.4681.00
373_Y480_L1.4671.00
386_M436_F1.4641.00
176_Y180_G1.4591.00
441_K444_K1.4571.00
175_I211_P1.4551.00
162_Y170_G1.4511.00
514_L519_A1.4501.00
238_E243_I1.4501.00
200_T254_E1.4351.00
552_T613_E1.4291.00
423_A528_G1.4231.00
79_L99_Y1.4221.00
87_V99_Y1.4071.00
310_I606_D1.4061.00
371_L462_A1.4031.00
520_F619_P1.4021.00
89_A237_M1.3991.00
421_A429_Y1.3981.00
423_A539_S1.3961.00
373_Y518_A1.3921.00
63_S305_K1.3861.00
177_Y184_I1.3821.00
572_K614_T1.3811.00
408_N412_A1.3731.00
418_L433_T1.3671.00
434_H439_T1.3661.00
502_V505_E1.3641.00
224_T228_E1.3571.00
77_V82_M1.3561.00
79_L82_M1.3491.00
405_S409_G1.3481.00
373_Y514_L1.3461.00
313_E606_D1.3461.00
41_A44_Q1.3321.00
553_Y570_N1.3321.00
97_N100_D1.3301.00
487_I510_H1.3281.00
166_E169_E1.3271.00
478_A574_A1.3241.00
420_Q423_A1.3221.00
235_R239_K1.3131.00
453_A472_E1.3101.00
145_W149_W1.3091.00
310_I314_T1.3071.00
579_T599_I1.3051.00
82_M86_I1.3041.00
494_R505_E1.3031.00
563_D578_W1.3011.00
277_A301_T1.3001.00
85_T201_D1.2991.00
376_I521_V1.2891.00
387_K415_P1.2861.00
377_Q518_A1.2831.00
377_Q445_T1.2831.00
512_Q516_E1.2751.00
575_A603_F1.2741.00
528_G539_S1.2731.00
202_A251_L1.2711.00
78_P169_E1.2691.00
445_T449_F1.2531.00
315_I329_F1.2531.00
496_T502_V1.2511.00
332_I574_A1.2501.00
426_D429_Y1.2501.00
311_A603_F1.2481.00
530_F553_Y1.2471.00
133_Y170_G1.2451.00
104_F152_A1.2451.00
568_G600_W1.2441.00
77_V196_A1.2391.00
416_I429_Y1.2331.00
486_K511_K1.2321.00
480_L569_F1.2271.00
179_H218_S1.2251.00
105_D108_R1.2241.00
238_E252_I1.2241.00
231_K252_I1.2231.00
329_F577_V1.2131.00
311_A343_V1.2101.00
373_Y445_T1.2081.00
470_P474_V1.2071.00
335_R572_K1.2041.00
435_L459_P1.2031.00
483_G516_E1.2021.00
280_E284_K1.2021.00
243_I248_A1.2021.00
370_L446_A1.2011.00
373_Y522_T1.1991.00
353_F359_A1.1971.00
110_A113_A1.1951.00
386_M429_Y1.1911.00
313_E317_E1.1901.00
223_E227_K1.1891.00
606_D609_K1.1881.00
249_D253_K1.1871.00
245_Q248_A1.1841.00
82_M87_V1.1841.00
126_A135_R1.1831.00
225_K228_E1.1831.00
482_N487_I1.1781.00
201_D234_V1.1771.00
417_T420_Q1.1751.00
246_K250_E1.1701.00
64_K67_E1.1701.00
342_L354_D1.1611.00
312_E316_T1.1601.00
449_F479_M1.1571.00
523_A554_A1.1571.00
375_A433_T1.1531.00
380_F436_F1.1501.00
275_D278_M1.1441.00
307_M341_A1.1441.00
247_K250_E1.1431.00
523_A526_M1.1431.00
418_L525_M1.1421.00
428_I432_K1.1401.00
194_K198_N1.1401.00
377_Q515_D1.1381.00
97_N101_H1.1381.00
249_D252_I1.1381.00
402_Y431_V1.1371.00
146_K150_N1.1351.00
380_F418_L1.1331.00
300_Y496_T1.1331.00
527_T552_T1.1321.00
361_R563_D1.1321.00
553_Y600_W1.1291.00
18_A22_L1.1251.00
59_A305_K1.1231.00
370_L449_F1.1201.00
575_A604_M1.1171.00
314_T602_D1.1151.00
380_F384_T1.1131.00
474_V567_I1.1121.00
172_L184_I1.1111.00
116_D122_K1.1111.00
60_S338_N1.1081.00
57_L68_T1.1051.00
109_M131_Q1.1041.00
354_D357_T1.1031.00
430_A433_T1.0991.00
552_T615_A1.0981.00
451_I468_V1.0971.00
448_E511_K1.0891.00
449_F514_L1.0861.00
362_Q560_T1.0851.00
216_G225_K1.0831.00
434_H462_A1.0821.00
297_L503_L1.0811.00
389_E432_K1.0801.00
392_E401_T1.0791.00
122_K143_K1.0781.00
281_L299_V1.0751.00
411_Y428_I1.0731.00
86_I172_L1.0701.00
89_A208_A1.0651.00
408_N426_D1.0641.00
202_A230_Q1.0491.00
579_T596_A1.0471.00
90_T172_L1.0471.00
176_Y182_Y1.0471.00
381_T384_T1.0451.00
235_R238_E1.0431.00
106_Y110_A1.0351.00
312_E343_V1.0321.00
273_F491_F1.0301.00
363_P367_I1.0301.00
481_A569_F1.0291.00
109_M126_A1.0281.00
422_L430_A1.0271.00
85_T247_K1.0261.00
97_N107_K1.0231.00
276_N280_E1.0171.00
157_R161_N1.0131.00
110_A114_L1.0121.00
380_F433_T1.0111.00
116_D145_W1.0061.00
332_I489_P1.0061.00
371_L442_L1.0051.00
440_N444_K1.0031.00
315_I343_V1.0021.00
376_I522_T1.0011.00
530_F542_G0.9971.00
122_K145_W0.9951.00
134_A138_Y0.9921.00
55_T299_V0.9911.00
334_P573_L0.9911.00
119_A122_K0.9901.00
445_T514_L0.9901.00
330_S342_L0.9851.00
209_G226_A0.9841.00
91_V242_M0.9841.00
62_G493_S0.9831.00
113_A116_D0.9801.00
250_E254_E0.9801.00
485_K510_H0.9791.00
57_L65_L0.9771.00
551_R572_K0.9761.00
227_K230_Q0.9751.00
520_F618_P0.9741.00
564_S596_A0.9741.00
440_N457_A0.9741.00
573_L607_A0.9741.00
388_S413_N0.9701.00
618_P624_G0.9701.00
115_A123_V0.9691.00
372_Y430_A0.9691.00
302_T338_N0.9681.00
281_L495_V0.9681.00
307_M603_F0.9671.00
285_L504_Y0.9661.00
185_E189_R0.9651.00
528_G531_D0.9651.00
593_K597_K0.9641.00
527_T615_A0.9611.00
330_S474_V0.9601.00
519_A522_T0.9591.00
428_I431_V0.9581.00
551_R612_P0.9571.00
470_P565_W0.9561.00
386_M418_L0.9561.00
445_T448_E0.9561.00
76_W169_E0.9541.00
276_N342_L0.9531.00
212_K217_Y0.9531.00
480_L523_A0.9491.00
469_R472_E0.9471.00
490_T506_N0.9461.00
577_V599_I0.9461.00
157_R160_Q0.9461.00
95_D101_H0.9441.00
130_T159_E0.9441.00
79_L168_L0.9431.00
494_R502_V0.9431.00
571_P616_F0.9411.00
318_T599_I0.9371.00
386_M433_T0.9361.00
456_Q466_E0.9351.00
517_K622_V0.9351.00
58_Y64_K0.9351.00
63_S306_R0.9281.00
539_S543_R0.9271.00
373_Y449_F0.9261.00
444_K447_K0.9241.00
88_K99_Y0.9231.00
437_L441_K0.9231.00
149_W153_F0.9191.00
87_V168_L0.9181.00
519_A523_A0.9161.00
443_V457_A0.9121.00
529_M542_G0.9121.00
394_Q401_T0.9091.00
443_V447_K0.9091.00
318_T602_D0.9091.00
136_N175_I0.9071.00
109_M152_A0.9031.00
416_I421_A0.9021.00
159_E167_I0.9001.00
391_T432_K0.8971.00
549_L552_T0.8961.00
422_L525_M0.8931.00
311_A341_A0.8931.00
479_M486_K0.8921.00
380_F386_M0.8901.00
412_A416_I0.8891.00
135_R141_H0.8891.00
275_D348_Y0.8891.00
412_A424_L0.8880.99
434_H461_L0.8860.99
272_Y345_G0.8860.99
443_V461_L0.8850.99
387_K432_K0.8820.99
93_I229_R0.8780.99
38_I41_A0.8780.99
437_L442_L0.8740.99
22_L26_A0.8730.99
331_A573_L0.8720.99
373_Y519_A0.8720.99
83_N204_A0.8700.99
564_S590_V0.8700.99
327_V599_I0.8700.99
366_T567_I0.8660.99
114_L118_K0.8620.99
83_N86_I0.8610.99
307_M331_A0.8600.99
434_H459_P0.8590.99
196_A199_L0.8590.99
564_S592_E0.8580.99
116_D119_A0.8550.99
339_V471_I0.8540.99
224_T227_K0.8540.99
470_P567_I0.8530.99
102_H106_Y0.8500.99
388_S412_A0.8490.99
551_R613_E0.8490.99
90_T184_I0.8490.99
562_A584_N0.8490.99
93_I212_K0.8450.99
129_I175_I0.8440.99
530_F566_M0.8420.99
333_D572_K0.8420.99
347_D350_K0.8390.99
431_V463_L0.8390.99
388_S411_Y0.8370.99
184_I207_L0.8370.99
106_Y109_M0.8360.99
75_Y185_E0.8350.99
468_V473_M0.8340.99
159_E164_K0.8330.99
116_D124_Q0.8320.99
305_K309_R0.8310.99
304_D307_M0.8310.99
527_T531_D0.8300.99
300_Y493_S0.8290.99
213_G217_Y0.8270.99
326_Q355_R0.8270.99
526_M569_F0.8250.99
179_H190_L0.8240.99
602_D606_D0.8210.99
77_V185_E0.8170.99
131_Q151_E0.8160.99
374_K442_L0.8150.99
276_N339_V0.8150.99
386_M432_K0.8150.99
531_D539_S0.8150.99
521_V622_V0.8140.99
342_L491_F0.8130.99
603_F607_A0.8100.99
56_I67_E0.8090.99
334_P481_A0.8090.99
87_V91_V0.8060.99
276_N279_R0.8050.99
563_D580_G0.8050.99
206_L209_G0.8050.99
275_D279_R0.8020.99
438_G441_K0.8010.99
291_Q295_S0.8010.99
193_G261_L0.7990.99
75_Y189_R0.7990.99
474_V574_A0.7940.99
302_T490_T0.7930.99
363_P467_P0.7910.99
369_P422_L0.7890.99
460_S465_T0.7880.99
193_G259_Q0.7860.99
372_Y422_L0.7840.99
334_P478_A0.7830.99
102_H156_I0.7800.99
367_I371_L0.7770.99
523_A616_F0.7750.99
572_K611_E0.7750.99
542_G566_M0.7750.99
136_N174_T0.7740.99
336_T490_T0.7720.99
145_W152_A0.7720.99
619_P622_V0.7720.99
363_P466_E0.7710.99
302_T493_S0.7710.99
515_D518_A0.7690.99
189_R195_H0.7670.99
542_G546_A0.7650.98
405_S411_Y0.7640.98
116_D126_A0.7630.98
206_L230_Q0.7600.98
104_F156_I0.7590.98
530_F555_G0.7590.98
243_I247_K0.7580.98
200_T204_A0.7560.98
449_F476_A0.7560.98
480_L514_L0.7540.98
82_M184_I0.7530.98
376_I518_A0.7510.98
246_K249_D0.7510.98
112_A116_D0.7500.98
520_F622_V0.7490.98
370_L473_M0.7470.98
25_F29_A0.7450.98
363_P473_M0.7440.98
90_T129_I0.7440.98
212_K216_G0.7430.98
518_A522_T0.7400.98
106_Y156_I0.7390.98
196_A204_A0.7390.98
66_G274_Y0.7370.98
53_Q76_W0.7370.98
287_M290_E0.7350.98
604_M608_L0.7350.98
439_T457_A0.7340.98
238_E249_D0.7340.98
139_L147_R0.7340.98
81_D185_E0.7310.98
37_V40_I0.7290.98
452_T472_E0.7290.98
514_L518_A0.7280.98
353_F356_T0.7270.98
393_F435_L0.7260.98
383_V419_L0.7250.98
551_R608_L0.7240.98
486_K513_V0.7240.98
115_A119_A0.7220.98
575_A600_W0.7210.98
326_Q350_K0.7200.98
376_I382_P0.7200.98
564_S595_Y0.7200.98
375_A380_F0.7200.98
516_E621_G0.7190.98
360_K472_E0.7180.98
473_M565_W0.7170.98
31_A35_M0.7170.98
307_M310_I0.7140.98
328_G355_R0.7130.98
115_A118_K0.7130.98
201_D204_A0.7120.98
319_V346_R0.7110.98
577_V600_W0.7110.98
188_S204_A0.7090.98
314_T599_I0.7090.98
451_I476_A0.7080.98
328_G470_P0.7060.97
17_R21_F0.7050.97
247_K251_L0.7050.97
91_V168_L0.7040.97
62_G300_Y0.7030.97
90_T175_I0.7020.97
176_Y181_A0.7020.97
492_I495_V0.7010.97
24_A27_A0.7010.97
61_D305_K0.7010.97
227_K256_L0.7010.97
332_I478_A0.6980.97
488_E509_Q0.6950.97
255_P258_Y0.6940.97
353_F358_Q0.6940.97
209_G233_I0.6930.97
232_T235_R0.6920.97
35_M38_I0.6890.97
569_F574_A0.6880.97
32_A36_T0.6880.97
364_A560_T0.6860.97
280_E492_I0.6850.97
529_M566_M0.6850.97
286_G290_E0.6850.97
40_I43_Y0.6830.97
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309_R312_E0.6790.97
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342_L357_T0.6780.97
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82_M85_T0.6720.97
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419_L525_M0.5860.93
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280_E283_K0.5810.93
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354_D358_Q0.5790.93
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393_F459_P0.5770.92
99_Y168_L0.5760.92
581_Y585_S0.5740.92
342_L356_T0.5740.92
92_A237_M0.5740.92
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206_L256_L0.5730.92
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319_V327_V0.5720.92
192_F206_L0.5720.92
432_K436_F0.5710.92
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73_K186_A0.5620.91
384_T433_T0.5620.91
25_F28_L0.5610.91
573_L608_L0.5610.91
123_V126_A0.5610.91
430_A525_M0.5610.91
430_A462_A0.5610.91
15_T19_F0.5610.91
188_S199_L0.5600.91
223_E226_A0.5600.91
564_S579_T0.5600.91
79_L83_N0.5600.91
445_T518_A0.5590.91
481_A574_A0.5590.91
210_I213_G0.5580.91
371_L434_H0.5580.91
16_V20_I0.5580.91
570_N604_M0.5580.91
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412_A420_Q0.5570.91
243_I251_L0.5570.91
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40_I44_Q0.5550.91
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33_V37_V0.5540.91
137_L170_G0.5520.91
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460_S467_P0.5520.91
270_A273_F0.5510.91
146_K149_W0.5510.91
522_T526_M0.5500.90
97_N159_E0.5500.90
326_Q345_G0.5500.90
480_L526_M0.5500.90
37_V41_A0.5490.90
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109_M145_W0.5440.90
206_L223_E0.5430.90
270_A309_R0.5430.90
597_K601_A0.5430.90
568_G577_V0.5420.90
332_I475_N0.5420.90
591_E594_S0.5410.90
77_V83_N0.5410.90
422_L526_M0.5410.90
429_Y432_K0.5400.90
276_N357_T0.5390.90
542_G597_K0.5390.90
331_A607_A0.5390.90
529_M541_T0.5390.90
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322_G581_Y0.5360.89
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592_E597_K0.5310.89
449_F480_L0.5310.89
237_M242_M0.5300.89
205_A251_L0.5300.89
618_P622_V0.5290.89
402_Y459_P0.5290.89
329_F341_A0.5290.89
138_Y154_Y0.5280.89
362_Q465_T0.5280.89
218_S221_V0.5270.89
205_A234_V0.5270.89
86_I208_A0.5270.89
478_A482_N0.5270.89
317_E320_N0.5260.88
280_E490_T0.5260.88
206_L220_Y0.5250.88
368_K427_N0.5250.88
272_Y326_Q0.5250.88
82_M169_E0.5250.88
372_Y525_M0.5250.88
371_L430_A0.5240.88
609_K612_P0.5240.88
388_S428_I0.5230.88
84_P242_M0.5230.88
202_A206_L0.5230.88
551_R571_P0.5220.88
74_R296_G0.5210.88
493_S505_E0.5210.88
111_G115_A0.5200.88
548_R551_R0.5200.88
244_S248_A0.5190.88
544_T597_K0.5190.88
327_V579_T0.5190.88
292_I296_G0.5180.88
130_T164_K0.5180.88
209_G229_R0.5180.88
207_L211_P0.5180.88
308_Q342_L0.5180.88
335_R482_N0.5170.88
273_F342_L0.5170.88
58_Y62_G0.5160.88
388_S429_Y0.5150.87
456_Q467_P0.5150.87
213_G225_K0.5150.87
530_F546_A0.5150.87
59_A65_L0.5140.87
317_E609_K0.5140.87
86_I177_Y0.5130.87
525_M528_G0.5130.87
153_F157_R0.5130.87
54_S73_K0.5120.87
188_S194_K0.5120.87
77_V184_I0.5110.87
237_M243_I0.5110.87
61_D304_D0.5110.87
516_E520_F0.5100.87
362_Q561_S0.5100.87
318_T598_T0.5100.87
93_I233_I0.5100.87
75_Y186_A0.5090.87
547_N553_Y0.5080.87
393_F402_Y0.5070.87
279_R358_Q0.5070.87
353_F582_D0.5070.87
425_S556_K0.5070.87
273_F277_A0.5070.87
335_R614_T0.5060.87
483_G523_A0.5060.87
547_N550_T0.5060.87
86_I201_D0.5060.87
408_N416_I0.5050.86
541_T566_M0.5050.86
328_G578_W0.5040.86
562_A583_K0.5040.86
454_H472_E0.5030.86
36_T40_I0.5020.86
282_E292_I0.5020.86
65_L303_V0.5020.86
44_Q47_P0.5010.86
93_I209_G0.5000.86
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4oonA 1 0.5514 100 0.144 Contact Map
3vmaA 1 0.8683 100 0.19 Contact Map
2jchA 1 0.6035 100 0.199 Contact Map
3udfA 2 0.699 100 0.207 Contact Map
2olvA 1 0.8321 100 0.254 Contact Map
3zg9B 1 0.6281 100 0.408 Contact Map
2y2mA 2 0.6411 100 0.566 Contact Map
3un7A 1 0.5166 100 0.631 Contact Map
2v2fF 1 0.4978 100 0.632 Contact Map
2oqoA 2 0.2619 100 0.649 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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