PBPG - BACSU - GREMLIN Contacts

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PBPG - Penicillin-binding protein 2D

UniProt:	P70997	Sequences: MDAMTNKRLRLTLKTVRAFIFLGAFAALAAAAVFMTVILIAKYQGAPSVQVPQSTILYASDGSKLGETNYGEKRYWVPLKDMNPTIVKATVAIEDQNFYDHHGFDYKRMAGAALADLKAFAKVQGASTITQQYARNLYLEHDKTWKRKWNEAFYTIRLEQNYSKDEILEGYLNTIYYGHGAYGIEAASRLYFGKHAKNLTDAEAALLAGIPKGPSGYSPYVNETKAKERQKTIVRMMEKQQMISQKKADELIKEPLSYQPLNKQVSKRKAPYFYDNAMRELEKKLGMTREQIETSGLNVYTTVDKRMQRIAEETITETVNAGSDIQVGFSAIDPRTGNVLALVGGRDYQKSPFDRTTQAKRQPASTIKPLLYYKAIQSGFTPVTLMKSEETEFQIDAKGETYSPSNYNGYYANKPITLLQALALSDNIYAVKTHLFLGTNKLVKTAKEFGITAHLQALPSLALGTEPVRPIEMVNAYAMLANGGKKIEPTFISRVTDAAGHVLYENPNQHKQVLDEKAAFVTASMMTGMFDIDLNGYTSVTGRTIANRLTRTYAGKSGTTSADSWMIGFNPKLAAGVWTGYDKNSTIDSVEEKSYAKTIWADFMEDALKGEPETAFKPPKGVTGVYIDPETGYSSGPGCAAKHYTYFVKGTEPANVCYGAEPAKQTKDRLPSKEKPASEKKWWDKWLGRHH	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	691 (596)
Sequences:	8552 (5855)
Seq/√Len:	239.8

ECOLI - PBPA PBPB PBPC
BACSU - PBPG PBPA PBPF PBPD YQGF PBPH PBPB SP5D

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
194_K	203_E	4.920	1.00
185_E	195_H	4.139	1.00
245_Q	249_D	4.029	1.00
474_V	576_G	3.893	1.00
238_E	248_A	3.823	1.00
244_S	247_K	3.816	1.00
567_I	576_G	3.418	1.00
497_D	501_H	3.290	1.00
416_I	426_D	3.252	1.00
84_P	88_K	3.219	1.00
331_A	575_A	3.212	1.00
331_A	603_F	3.104	1.00
227_K	231_K	3.022	1.00
273_F	302_T	2.915	1.00
485_K	512_Q	2.902	1.00
315_I	327_V	2.856	1.00
523_A	569_F	2.854	1.00
238_E	245_Q	2.837	1.00
86_I	184_I	2.677	1.00
185_E	196_A	2.613	1.00
99_Y	165_D	2.508	1.00
235_R	252_I	2.503	1.00
97_N	105_D	2.483	1.00
334_P	574_A	2.478	1.00
108_R	111_G	2.454	1.00
60_S	304_D	2.379	1.00
88_K	242_M	2.359	1.00
163_S	166_E	2.351	1.00
392_E	403_S	2.318	1.00
248_A	252_I	2.306	1.00
79_L	87_V	2.270	1.00
378_S	441_K	2.259	1.00
58_Y	298_N	2.258	1.00
59_A	63_S	2.236	1.00
329_F	603_F	2.233	1.00
84_P	87_V	2.208	1.00
202_A	254_E	2.208	1.00
78_P	81_D	2.206	1.00
333_D	336_T	2.191	1.00
201_D	243_I	2.168	1.00
420_Q	424_L	2.160	1.00
419_L	524_S	2.140	1.00
338_N	490_T	2.123	1.00
93_I	232_T	2.123	1.00
79_L	169_E	2.105	1.00
339_V	491_F	2.104	1.00
56_I	64_K	2.072	1.00
338_N	493_S	2.067	1.00
87_V	165_D	2.055	1.00
83_N	196_A	2.044	1.00
475_N	489_P	2.041	1.00
300_Y	494_R	2.026	1.00
206_L	226_A	1.989	1.00
311_A	329_F	1.984	1.00
419_L	528_G	1.942	1.00
79_L	165_D	1.933	1.00
85_T	204_A	1.927	1.00
340_L	573_L	1.906	1.00
317_E	602_D	1.905	1.00
475_N	486_K	1.903	1.00
96_Q	236_M	1.897	1.00
333_D	340_L	1.882	1.00
115_A	124_Q	1.880	1.00
374_K	445_T	1.876	1.00
81_D	197_K	1.869	1.00
377_Q	448_E	1.866	1.00
407_Y	591_E	1.861	1.00
524_S	527_T	1.860	1.00
85_T	88_K	1.857	1.00
101_H	159_E	1.826	1.00
355_R	582_D	1.821	1.00
363_P	468_V	1.820	1.00
470_P	576_G	1.813	1.00
90_T	208_A	1.801	1.00
201_D	251_L	1.791	1.00
181_A	190_L	1.759	1.00
213_G	216_G	1.756	1.00
235_R	248_A	1.751	1.00
236_M	239_K	1.750	1.00
276_N	491_F	1.747	1.00
480_L	522_T	1.746	1.00
608_L	611_E	1.728	1.00
473_M	567_I	1.728	1.00
333_D	338_N	1.717	1.00
483_G	520_F	1.715	1.00
412_A	426_D	1.714	1.00
93_I	236_M	1.710	1.00
234_V	248_A	1.704	1.00
370_L	476_A	1.703	1.00
382_P	521_V	1.701	1.00
367_I	446_A	1.688	1.00
92_A	242_M	1.674	1.00
86_I	204_A	1.669	1.00
195_H	198_N	1.664	1.00
444_K	448_E	1.663	1.00
330_S	471_I	1.659	1.00
434_H	442_L	1.656	1.00
307_M	607_A	1.645	1.00
58_Y	300_Y	1.644	1.00
91_V	99_Y	1.638	1.00
298_N	496_T	1.631	1.00
330_S	470_P	1.629	1.00
96_Q	240_Q	1.629	1.00
376_I	525_M	1.627	1.00
369_P	480_L	1.617	1.00
382_P	525_M	1.616	1.00
385_L	415_P	1.610	1.00
90_T	177_Y	1.608	1.00
134_A	158_L	1.608	1.00
56_I	298_N	1.605	1.00
236_M	240_Q	1.596	1.00
111_G	124_Q	1.578	1.00
309_R	313_E	1.577	1.00
555_G	566_M	1.575	1.00
517_K	621_G	1.569	1.00
92_A	240_Q	1.568	1.00
600_W	604_M	1.546	1.00
60_S	340_L	1.541	1.00
86_I	90_T	1.528	1.00
554_A	569_F	1.527	1.00
329_F	575_A	1.499	1.00
332_I	474_V	1.490	1.00
199_L	204_A	1.489	1.00
601_A	605_E	1.483	1.00
189_R	193_G	1.481	1.00
366_T	473_M	1.481	1.00
222_N	225_K	1.479	1.00
90_T	211_P	1.477	1.00
119_A	123_V	1.475	1.00
273_F	303_V	1.474	1.00
307_M	340_L	1.468	1.00
373_Y	480_L	1.467	1.00
386_M	436_F	1.464	1.00
176_Y	180_G	1.459	1.00
441_K	444_K	1.457	1.00
175_I	211_P	1.455	1.00
162_Y	170_G	1.451	1.00
514_L	519_A	1.450	1.00
238_E	243_I	1.450	1.00
200_T	254_E	1.435	1.00
552_T	613_E	1.429	1.00
423_A	528_G	1.423	1.00
79_L	99_Y	1.422	1.00
87_V	99_Y	1.407	1.00
310_I	606_D	1.406	1.00
371_L	462_A	1.403	1.00
520_F	619_P	1.402	1.00
89_A	237_M	1.399	1.00
421_A	429_Y	1.398	1.00
423_A	539_S	1.396	1.00
373_Y	518_A	1.392	1.00
63_S	305_K	1.386	1.00
177_Y	184_I	1.382	1.00
572_K	614_T	1.381	1.00
408_N	412_A	1.373	1.00
418_L	433_T	1.367	1.00
434_H	439_T	1.366	1.00
502_V	505_E	1.364	1.00
224_T	228_E	1.357	1.00
77_V	82_M	1.356	1.00
79_L	82_M	1.349	1.00
405_S	409_G	1.348	1.00
373_Y	514_L	1.346	1.00
313_E	606_D	1.346	1.00
41_A	44_Q	1.332	1.00
553_Y	570_N	1.332	1.00
97_N	100_D	1.330	1.00
487_I	510_H	1.328	1.00
166_E	169_E	1.327	1.00
478_A	574_A	1.324	1.00
420_Q	423_A	1.322	1.00
235_R	239_K	1.313	1.00
453_A	472_E	1.310	1.00
145_W	149_W	1.309	1.00
310_I	314_T	1.307	1.00
579_T	599_I	1.305	1.00
82_M	86_I	1.304	1.00
494_R	505_E	1.303	1.00
563_D	578_W	1.301	1.00
277_A	301_T	1.300	1.00
85_T	201_D	1.299	1.00
376_I	521_V	1.289	1.00
387_K	415_P	1.286	1.00
377_Q	518_A	1.283	1.00
377_Q	445_T	1.283	1.00
512_Q	516_E	1.275	1.00
575_A	603_F	1.274	1.00
528_G	539_S	1.273	1.00
202_A	251_L	1.271	1.00
78_P	169_E	1.269	1.00
445_T	449_F	1.253	1.00
315_I	329_F	1.253	1.00
496_T	502_V	1.251	1.00
332_I	574_A	1.250	1.00
426_D	429_Y	1.250	1.00
311_A	603_F	1.248	1.00
530_F	553_Y	1.247	1.00
133_Y	170_G	1.245	1.00
104_F	152_A	1.245	1.00
568_G	600_W	1.244	1.00
77_V	196_A	1.239	1.00
416_I	429_Y	1.233	1.00
486_K	511_K	1.232	1.00
480_L	569_F	1.227	1.00
179_H	218_S	1.225	1.00
105_D	108_R	1.224	1.00
238_E	252_I	1.224	1.00
231_K	252_I	1.223	1.00
329_F	577_V	1.213	1.00
311_A	343_V	1.210	1.00
373_Y	445_T	1.208	1.00
470_P	474_V	1.207	1.00
335_R	572_K	1.204	1.00
435_L	459_P	1.203	1.00
483_G	516_E	1.202	1.00
280_E	284_K	1.202	1.00
243_I	248_A	1.202	1.00
370_L	446_A	1.201	1.00
373_Y	522_T	1.199	1.00
353_F	359_A	1.197	1.00
110_A	113_A	1.195	1.00
386_M	429_Y	1.191	1.00
313_E	317_E	1.190	1.00
223_E	227_K	1.189	1.00
606_D	609_K	1.188	1.00
249_D	253_K	1.187	1.00
245_Q	248_A	1.184	1.00
82_M	87_V	1.184	1.00
126_A	135_R	1.183	1.00
225_K	228_E	1.183	1.00
482_N	487_I	1.178	1.00
201_D	234_V	1.177	1.00
417_T	420_Q	1.175	1.00
246_K	250_E	1.170	1.00
64_K	67_E	1.170	1.00
342_L	354_D	1.161	1.00
312_E	316_T	1.160	1.00
449_F	479_M	1.157	1.00
523_A	554_A	1.157	1.00
375_A	433_T	1.153	1.00
380_F	436_F	1.150	1.00
275_D	278_M	1.144	1.00
307_M	341_A	1.144	1.00
247_K	250_E	1.143	1.00
523_A	526_M	1.143	1.00
418_L	525_M	1.142	1.00
428_I	432_K	1.140	1.00
194_K	198_N	1.140	1.00
377_Q	515_D	1.138	1.00
97_N	101_H	1.138	1.00
249_D	252_I	1.138	1.00
402_Y	431_V	1.137	1.00
146_K	150_N	1.135	1.00
380_F	418_L	1.133	1.00
300_Y	496_T	1.133	1.00
527_T	552_T	1.132	1.00
361_R	563_D	1.132	1.00
553_Y	600_W	1.129	1.00
18_A	22_L	1.125	1.00
59_A	305_K	1.123	1.00
370_L	449_F	1.120	1.00
575_A	604_M	1.117	1.00
314_T	602_D	1.115	1.00
380_F	384_T	1.113	1.00
474_V	567_I	1.112	1.00
172_L	184_I	1.111	1.00
116_D	122_K	1.111	1.00
60_S	338_N	1.108	1.00
57_L	68_T	1.105	1.00
109_M	131_Q	1.104	1.00
354_D	357_T	1.103	1.00
430_A	433_T	1.099	1.00
552_T	615_A	1.098	1.00
451_I	468_V	1.097	1.00
448_E	511_K	1.089	1.00
449_F	514_L	1.086	1.00
362_Q	560_T	1.085	1.00
216_G	225_K	1.083	1.00
434_H	462_A	1.082	1.00
297_L	503_L	1.081	1.00
389_E	432_K	1.080	1.00
392_E	401_T	1.079	1.00
122_K	143_K	1.078	1.00
281_L	299_V	1.075	1.00
411_Y	428_I	1.073	1.00
86_I	172_L	1.070	1.00
89_A	208_A	1.065	1.00
408_N	426_D	1.064	1.00
202_A	230_Q	1.049	1.00
579_T	596_A	1.047	1.00
90_T	172_L	1.047	1.00
176_Y	182_Y	1.047	1.00
381_T	384_T	1.045	1.00
235_R	238_E	1.043	1.00
106_Y	110_A	1.035	1.00
312_E	343_V	1.032	1.00
273_F	491_F	1.030	1.00
363_P	367_I	1.030	1.00
481_A	569_F	1.029	1.00
109_M	126_A	1.028	1.00
422_L	430_A	1.027	1.00
85_T	247_K	1.026	1.00
97_N	107_K	1.023	1.00
276_N	280_E	1.017	1.00
157_R	161_N	1.013	1.00
110_A	114_L	1.012	1.00
380_F	433_T	1.011	1.00
116_D	145_W	1.006	1.00
332_I	489_P	1.006	1.00
371_L	442_L	1.005	1.00
440_N	444_K	1.003	1.00
315_I	343_V	1.002	1.00
376_I	522_T	1.001	1.00
530_F	542_G	0.997	1.00
122_K	145_W	0.995	1.00
134_A	138_Y	0.992	1.00
55_T	299_V	0.991	1.00
334_P	573_L	0.991	1.00
119_A	122_K	0.990	1.00
445_T	514_L	0.990	1.00
330_S	342_L	0.985	1.00
209_G	226_A	0.984	1.00
91_V	242_M	0.984	1.00
62_G	493_S	0.983	1.00
113_A	116_D	0.980	1.00
250_E	254_E	0.980	1.00
485_K	510_H	0.979	1.00
57_L	65_L	0.977	1.00
551_R	572_K	0.976	1.00
227_K	230_Q	0.975	1.00
520_F	618_P	0.974	1.00
564_S	596_A	0.974	1.00
440_N	457_A	0.974	1.00
573_L	607_A	0.974	1.00
388_S	413_N	0.970	1.00
618_P	624_G	0.970	1.00
115_A	123_V	0.969	1.00
372_Y	430_A	0.969	1.00
302_T	338_N	0.968	1.00
281_L	495_V	0.968	1.00
307_M	603_F	0.967	1.00
285_L	504_Y	0.966	1.00
185_E	189_R	0.965	1.00
528_G	531_D	0.965	1.00
593_K	597_K	0.964	1.00
527_T	615_A	0.961	1.00
330_S	474_V	0.960	1.00
519_A	522_T	0.959	1.00
428_I	431_V	0.958	1.00
551_R	612_P	0.957	1.00
470_P	565_W	0.956	1.00
386_M	418_L	0.956	1.00
445_T	448_E	0.956	1.00
76_W	169_E	0.954	1.00
276_N	342_L	0.953	1.00
212_K	217_Y	0.953	1.00
480_L	523_A	0.949	1.00
469_R	472_E	0.947	1.00
490_T	506_N	0.946	1.00
577_V	599_I	0.946	1.00
157_R	160_Q	0.946	1.00
95_D	101_H	0.944	1.00
130_T	159_E	0.944	1.00
79_L	168_L	0.943	1.00
494_R	502_V	0.943	1.00
571_P	616_F	0.941	1.00
318_T	599_I	0.937	1.00
386_M	433_T	0.936	1.00
456_Q	466_E	0.935	1.00
517_K	622_V	0.935	1.00
58_Y	64_K	0.935	1.00
63_S	306_R	0.928	1.00
539_S	543_R	0.927	1.00
373_Y	449_F	0.926	1.00
444_K	447_K	0.924	1.00
88_K	99_Y	0.923	1.00
437_L	441_K	0.923	1.00
149_W	153_F	0.919	1.00
87_V	168_L	0.918	1.00
519_A	523_A	0.916	1.00
443_V	457_A	0.912	1.00
529_M	542_G	0.912	1.00
394_Q	401_T	0.909	1.00
443_V	447_K	0.909	1.00
318_T	602_D	0.909	1.00
136_N	175_I	0.907	1.00
109_M	152_A	0.903	1.00
416_I	421_A	0.902	1.00
159_E	167_I	0.900	1.00
391_T	432_K	0.897	1.00
549_L	552_T	0.896	1.00
422_L	525_M	0.893	1.00
311_A	341_A	0.893	1.00
479_M	486_K	0.892	1.00
380_F	386_M	0.890	1.00
412_A	416_I	0.889	1.00
135_R	141_H	0.889	1.00
275_D	348_Y	0.889	1.00
412_A	424_L	0.888	0.99
434_H	461_L	0.886	0.99
272_Y	345_G	0.886	0.99
443_V	461_L	0.885	0.99
387_K	432_K	0.882	0.99
93_I	229_R	0.878	0.99
38_I	41_A	0.878	0.99
437_L	442_L	0.874	0.99
22_L	26_A	0.873	0.99
331_A	573_L	0.872	0.99
373_Y	519_A	0.872	0.99
83_N	204_A	0.870	0.99
564_S	590_V	0.870	0.99
327_V	599_I	0.870	0.99
366_T	567_I	0.866	0.99
114_L	118_K	0.862	0.99
83_N	86_I	0.861	0.99
307_M	331_A	0.860	0.99
434_H	459_P	0.859	0.99
196_A	199_L	0.859	0.99
564_S	592_E	0.858	0.99
116_D	119_A	0.855	0.99
339_V	471_I	0.854	0.99
224_T	227_K	0.854	0.99
470_P	567_I	0.853	0.99
102_H	106_Y	0.850	0.99
388_S	412_A	0.849	0.99
551_R	613_E	0.849	0.99
90_T	184_I	0.849	0.99
562_A	584_N	0.849	0.99
93_I	212_K	0.845	0.99
129_I	175_I	0.844	0.99
530_F	566_M	0.842	0.99
333_D	572_K	0.842	0.99
347_D	350_K	0.839	0.99
431_V	463_L	0.839	0.99
388_S	411_Y	0.837	0.99
184_I	207_L	0.837	0.99
106_Y	109_M	0.836	0.99
75_Y	185_E	0.835	0.99
468_V	473_M	0.834	0.99
159_E	164_K	0.833	0.99
116_D	124_Q	0.832	0.99
305_K	309_R	0.831	0.99
304_D	307_M	0.831	0.99
527_T	531_D	0.830	0.99
300_Y	493_S	0.829	0.99
213_G	217_Y	0.827	0.99
326_Q	355_R	0.827	0.99
526_M	569_F	0.825	0.99
179_H	190_L	0.824	0.99
602_D	606_D	0.821	0.99
77_V	185_E	0.817	0.99
131_Q	151_E	0.816	0.99
374_K	442_L	0.815	0.99
276_N	339_V	0.815	0.99
386_M	432_K	0.815	0.99
531_D	539_S	0.815	0.99
521_V	622_V	0.814	0.99
342_L	491_F	0.813	0.99
603_F	607_A	0.810	0.99
56_I	67_E	0.809	0.99
334_P	481_A	0.809	0.99
87_V	91_V	0.806	0.99
276_N	279_R	0.805	0.99
563_D	580_G	0.805	0.99
206_L	209_G	0.805	0.99
275_D	279_R	0.802	0.99
438_G	441_K	0.801	0.99
291_Q	295_S	0.801	0.99
193_G	261_L	0.799	0.99
75_Y	189_R	0.799	0.99
474_V	574_A	0.794	0.99
302_T	490_T	0.793	0.99
363_P	467_P	0.791	0.99
369_P	422_L	0.789	0.99
460_S	465_T	0.788	0.99
193_G	259_Q	0.786	0.99
372_Y	422_L	0.784	0.99
334_P	478_A	0.783	0.99
102_H	156_I	0.780	0.99
367_I	371_L	0.777	0.99
523_A	616_F	0.775	0.99
572_K	611_E	0.775	0.99
542_G	566_M	0.775	0.99
136_N	174_T	0.774	0.99
336_T	490_T	0.772	0.99
145_W	152_A	0.772	0.99
619_P	622_V	0.772	0.99
363_P	466_E	0.771	0.99
302_T	493_S	0.771	0.99
515_D	518_A	0.769	0.99
189_R	195_H	0.767	0.99
542_G	546_A	0.765	0.98
405_S	411_Y	0.764	0.98
116_D	126_A	0.763	0.98
206_L	230_Q	0.760	0.98
104_F	156_I	0.759	0.98
530_F	555_G	0.759	0.98
243_I	247_K	0.758	0.98
200_T	204_A	0.756	0.98
449_F	476_A	0.756	0.98
480_L	514_L	0.754	0.98
82_M	184_I	0.753	0.98
376_I	518_A	0.751	0.98
246_K	249_D	0.751	0.98
112_A	116_D	0.750	0.98
520_F	622_V	0.749	0.98
370_L	473_M	0.747	0.98
25_F	29_A	0.745	0.98
363_P	473_M	0.744	0.98
90_T	129_I	0.744	0.98
212_K	216_G	0.743	0.98
518_A	522_T	0.740	0.98
106_Y	156_I	0.739	0.98
196_A	204_A	0.739	0.98
66_G	274_Y	0.737	0.98
53_Q	76_W	0.737	0.98
287_M	290_E	0.735	0.98
604_M	608_L	0.735	0.98
439_T	457_A	0.734	0.98
238_E	249_D	0.734	0.98
139_L	147_R	0.734	0.98
81_D	185_E	0.731	0.98
37_V	40_I	0.729	0.98
452_T	472_E	0.729	0.98
514_L	518_A	0.728	0.98
353_F	356_T	0.727	0.98
393_F	435_L	0.726	0.98
383_V	419_L	0.725	0.98
551_R	608_L	0.724	0.98
486_K	513_V	0.724	0.98
115_A	119_A	0.722	0.98
575_A	600_W	0.721	0.98
326_Q	350_K	0.720	0.98
376_I	382_P	0.720	0.98
564_S	595_Y	0.720	0.98
375_A	380_F	0.720	0.98
516_E	621_G	0.719	0.98
360_K	472_E	0.718	0.98
473_M	565_W	0.717	0.98
31_A	35_M	0.717	0.98
307_M	310_I	0.714	0.98
328_G	355_R	0.713	0.98
115_A	118_K	0.713	0.98
201_D	204_A	0.712	0.98
319_V	346_R	0.711	0.98
577_V	600_W	0.711	0.98
188_S	204_A	0.709	0.98
314_T	599_I	0.709	0.98
451_I	476_A	0.708	0.98
328_G	470_P	0.706	0.97
17_R	21_F	0.705	0.97
247_K	251_L	0.705	0.97
91_V	168_L	0.704	0.97
62_G	300_Y	0.703	0.97
90_T	175_I	0.702	0.97
176_Y	181_A	0.702	0.97
492_I	495_V	0.701	0.97
24_A	27_A	0.701	0.97
61_D	305_K	0.701	0.97
227_K	256_L	0.701	0.97
332_I	478_A	0.698	0.97
488_E	509_Q	0.695	0.97
255_P	258_Y	0.694	0.97
353_F	358_Q	0.694	0.97
209_G	233_I	0.693	0.97
232_T	235_R	0.692	0.97
35_M	38_I	0.689	0.97
569_F	574_A	0.688	0.97
32_A	36_T	0.688	0.97
364_A	560_T	0.686	0.97
280_E	492_I	0.685	0.97
529_M	566_M	0.685	0.97
286_G	290_E	0.685	0.97
40_I	43_Y	0.683	0.97
548_R	553_Y	0.683	0.97
93_I	211_P	0.680	0.97
309_R	312_E	0.679	0.97
286_G	291_Q	0.679	0.97
208_A	211_P	0.679	0.97
251_L	254_E	0.678	0.97
342_L	357_T	0.678	0.97
284_K	504_Y	0.678	0.97
232_T	236_M	0.678	0.97
406_N	411_Y	0.676	0.97
441_K	445_T	0.675	0.97
527_T	530_F	0.675	0.97
306_R	610_G	0.675	0.97
360_K	467_P	0.674	0.97
201_D	237_M	0.673	0.97
388_S	426_D	0.673	0.97
326_Q	582_D	0.673	0.97
82_M	85_T	0.672	0.97
212_K	233_I	0.672	0.97
376_I	418_L	0.671	0.97
32_A	35_M	0.670	0.97
254_E	257_S	0.670	0.97
310_I	313_E	0.670	0.97
577_V	596_A	0.669	0.97
524_S	528_G	0.669	0.97
116_D	152_A	0.667	0.96
526_M	554_A	0.667	0.96
22_L	25_F	0.666	0.96
30_A	34_F	0.666	0.96
254_E	258_Y	0.666	0.96
277_A	281_L	0.665	0.96
104_F	109_M	0.664	0.96
475_N	488_E	0.664	0.96
416_I	420_Q	0.663	0.96
139_L	154_Y	0.662	0.96
423_A	529_M	0.662	0.96
345_G	355_R	0.660	0.96
481_A	554_A	0.660	0.96
142_D	147_R	0.658	0.96
287_M	291_Q	0.658	0.96
325_I	581_Y	0.658	0.96
130_T	155_T	0.657	0.96
19_F	23_G	0.657	0.96
134_A	154_Y	0.655	0.96
178_G	191_Y	0.652	0.96
281_L	297_L	0.652	0.96
311_A	331_A	0.650	0.96
68_T	278_M	0.650	0.96
86_I	199_L	0.648	0.96
280_E	491_F	0.648	0.96
374_K	378_S	0.648	0.96
135_R	143_K	0.647	0.96
230_Q	256_L	0.647	0.96
177_Y	211_P	0.645	0.96
554_A	616_F	0.645	0.96
304_D	340_L	0.644	0.96
320_N	346_R	0.643	0.96
306_R	310_I	0.642	0.96
209_G	232_T	0.642	0.96
374_K	437_L	0.640	0.96
93_I	208_A	0.640	0.96
79_L	91_V	0.639	0.95
238_E	241_Q	0.636	0.95
447_K	454_H	0.635	0.95
529_M	555_G	0.635	0.95
185_E	197_K	0.633	0.95
570_N	608_L	0.632	0.95
20_I	23_G	0.632	0.95
281_L	292_I	0.632	0.95
390_E	411_Y	0.631	0.95
592_E	596_A	0.631	0.95
479_M	513_V	0.630	0.95
360_K	469_R	0.630	0.95
86_I	196_A	0.630	0.95
281_L	284_K	0.629	0.95
206_L	219_P	0.628	0.95
204_A	211_P	0.627	0.95
89_A	242_M	0.627	0.95
471_I	474_V	0.624	0.95
16_V	19_F	0.623	0.95
33_V	36_T	0.623	0.95
93_I	240_Q	0.623	0.95
281_L	285_L	0.623	0.95
29_A	33_V	0.622	0.95
168_L	172_L	0.622	0.95
162_Y	166_E	0.621	0.95
230_Q	255_P	0.620	0.95
54_S	67_E	0.619	0.95
306_R	309_R	0.619	0.95
194_K	200_T	0.619	0.95
479_M	514_L	0.618	0.95
131_Q	139_L	0.617	0.95
473_M	576_G	0.616	0.95
184_I	196_A	0.616	0.95
123_V	143_K	0.616	0.95
564_S	593_K	0.616	0.95
135_R	147_R	0.614	0.94
212_K	229_R	0.613	0.94
115_A	122_K	0.612	0.94
35_M	39_L	0.612	0.94
569_F	604_M	0.612	0.94
118_K	122_K	0.611	0.94
80_K	165_D	0.607	0.94
78_P	82_M	0.607	0.94
447_K	452_T	0.607	0.94
122_K	126_A	0.605	0.94
495_V	504_Y	0.604	0.94
604_M	607_A	0.603	0.94
282_E	286_G	0.601	0.94
531_D	547_N	0.601	0.94
314_T	606_D	0.599	0.94
449_F	513_V	0.599	0.94
446_A	451_I	0.599	0.94
212_K	232_T	0.598	0.94
590_V	595_Y	0.598	0.94
376_I	380_F	0.594	0.93
26_A	30_A	0.594	0.93
529_M	540_V	0.594	0.93
374_K	441_K	0.593	0.93
27_A	30_A	0.593	0.93
113_A	117_L	0.592	0.93
568_G	604_M	0.591	0.93
188_S	196_A	0.590	0.93
468_V	472_E	0.589	0.93
446_A	476_A	0.587	0.93
271_P	274_Y	0.587	0.93
419_L	525_M	0.586	0.93
334_P	571_P	0.585	0.93
270_A	305_K	0.584	0.93
57_L	277_A	0.584	0.93
475_N	478_A	0.584	0.93
52_P	72_E	0.584	0.93
234_V	251_L	0.582	0.93
280_E	283_K	0.581	0.93
560_T	563_D	0.580	0.93
116_D	143_K	0.580	0.93
273_F	276_N	0.579	0.93
354_D	358_Q	0.579	0.93
452_T	455_L	0.578	0.92
548_R	552_T	0.578	0.92
458_L	465_T	0.577	0.92
393_F	459_P	0.577	0.92
99_Y	168_L	0.576	0.92
581_Y	585_S	0.574	0.92
342_L	356_T	0.574	0.92
92_A	237_M	0.574	0.92
544_T	598_T	0.573	0.92
206_L	256_L	0.573	0.92
385_L	417_T	0.573	0.92
319_V	327_V	0.572	0.92
192_F	206_L	0.572	0.92
432_K	436_F	0.571	0.92
113_A	145_W	0.570	0.92
147_R	151_E	0.570	0.92
347_D	351_S	0.569	0.92
124_Q	143_K	0.569	0.92
230_Q	258_Y	0.569	0.92
515_D	519_A	0.568	0.92
22_L	29_A	0.567	0.92
573_L	603_F	0.567	0.92
365_S	368_K	0.566	0.92
131_Q	135_R	0.565	0.92
478_A	487_I	0.565	0.92
497_D	500_G	0.564	0.92
108_R	124_Q	0.564	0.92
546_A	549_L	0.563	0.91
96_Q	239_K	0.563	0.91
102_H	159_E	0.562	0.91
73_K	186_A	0.562	0.91
384_T	433_T	0.562	0.91
25_F	28_L	0.561	0.91
573_L	608_L	0.561	0.91
123_V	126_A	0.561	0.91
430_A	525_M	0.561	0.91
430_A	462_A	0.561	0.91
15_T	19_F	0.561	0.91
188_S	199_L	0.560	0.91
223_E	226_A	0.560	0.91
564_S	579_T	0.560	0.91
79_L	83_N	0.560	0.91
445_T	518_A	0.559	0.91
481_A	574_A	0.559	0.91
210_I	213_G	0.558	0.91
371_L	434_H	0.558	0.91
16_V	20_I	0.558	0.91
570_N	604_M	0.558	0.91
566_M	600_W	0.558	0.91
412_A	420_Q	0.557	0.91
243_I	251_L	0.557	0.91
483_G	617_K	0.556	0.91
420_Q	539_S	0.555	0.91
40_I	44_Q	0.555	0.91
188_S	192_F	0.555	0.91
363_P	366_T	0.555	0.91
115_A	121_A	0.554	0.91
33_V	37_V	0.554	0.91
137_L	170_G	0.552	0.91
38_I	44_Q	0.552	0.91
460_S	467_P	0.552	0.91
270_A	273_F	0.551	0.91
146_K	149_W	0.551	0.91
522_T	526_M	0.550	0.90
97_N	159_E	0.550	0.90
326_Q	345_G	0.550	0.90
480_L	526_M	0.550	0.90
37_V	41_A	0.549	0.90
120_F	124_Q	0.549	0.90
471_I	491_F	0.549	0.90
369_P	477_Y	0.549	0.90
179_H	220_Y	0.548	0.90
324_D	581_Y	0.547	0.90
361_R	578_W	0.547	0.90
139_L	142_D	0.546	0.90
383_V	627_I	0.546	0.90
43_Y	47_P	0.546	0.90
82_M	90_T	0.546	0.90
330_S	356_T	0.545	0.90
548_R	605_E	0.545	0.90
15_T	18_A	0.545	0.90
551_R	610_G	0.545	0.90
152_A	155_T	0.545	0.90
330_S	574_A	0.544	0.90
523_A	527_T	0.544	0.90
109_M	145_W	0.544	0.90
206_L	223_E	0.543	0.90
270_A	309_R	0.543	0.90
597_K	601_A	0.543	0.90
568_G	577_V	0.542	0.90
332_I	475_N	0.542	0.90
591_E	594_S	0.541	0.90
77_V	83_N	0.541	0.90
422_L	526_M	0.541	0.90
429_Y	432_K	0.540	0.90
276_N	357_T	0.539	0.90
542_G	597_K	0.539	0.90
331_A	607_A	0.539	0.90
529_M	541_T	0.539	0.90
422_L	522_T	0.536	0.89
322_G	581_Y	0.536	0.89
59_A	62_G	0.535	0.89
592_E	597_K	0.531	0.89
449_F	480_L	0.531	0.89
237_M	242_M	0.530	0.89
205_A	251_L	0.530	0.89
618_P	622_V	0.529	0.89
402_Y	459_P	0.529	0.89
329_F	341_A	0.529	0.89
138_Y	154_Y	0.528	0.89
362_Q	465_T	0.528	0.89
218_S	221_V	0.527	0.89
205_A	234_V	0.527	0.89
86_I	208_A	0.527	0.89
478_A	482_N	0.527	0.89
317_E	320_N	0.526	0.88
280_E	490_T	0.526	0.88
206_L	220_Y	0.525	0.88
368_K	427_N	0.525	0.88
272_Y	326_Q	0.525	0.88
82_M	169_E	0.525	0.88
372_Y	525_M	0.525	0.88
371_L	430_A	0.524	0.88
609_K	612_P	0.524	0.88
388_S	428_I	0.523	0.88
84_P	242_M	0.523	0.88
202_A	206_L	0.523	0.88
551_R	571_P	0.522	0.88
74_R	296_G	0.521	0.88
493_S	505_E	0.521	0.88
111_G	115_A	0.520	0.88
548_R	551_R	0.520	0.88
244_S	248_A	0.519	0.88
544_T	597_K	0.519	0.88
327_V	579_T	0.519	0.88
292_I	296_G	0.518	0.88
130_T	164_K	0.518	0.88
209_G	229_R	0.518	0.88
207_L	211_P	0.518	0.88
308_Q	342_L	0.518	0.88
335_R	482_N	0.517	0.88
273_F	342_L	0.517	0.88
58_Y	62_G	0.516	0.88
388_S	429_Y	0.515	0.87
456_Q	467_P	0.515	0.87
213_G	225_K	0.515	0.87
530_F	546_A	0.515	0.87
59_A	65_L	0.514	0.87
317_E	609_K	0.514	0.87
86_I	177_Y	0.513	0.87
525_M	528_G	0.513	0.87
153_F	157_R	0.513	0.87
54_S	73_K	0.512	0.87
188_S	194_K	0.512	0.87
77_V	184_I	0.511	0.87
237_M	243_I	0.511	0.87
61_D	304_D	0.511	0.87
516_E	520_F	0.510	0.87
362_Q	561_S	0.510	0.87
318_T	598_T	0.510	0.87
93_I	233_I	0.510	0.87
75_Y	186_A	0.509	0.87
547_N	553_Y	0.508	0.87
393_F	402_Y	0.507	0.87
279_R	358_Q	0.507	0.87
353_F	582_D	0.507	0.87
425_S	556_K	0.507	0.87
273_F	277_A	0.507	0.87
335_R	614_T	0.506	0.87
483_G	523_A	0.506	0.87
547_N	550_T	0.506	0.87
86_I	201_D	0.506	0.87
408_N	416_I	0.505	0.86
541_T	566_M	0.505	0.86
328_G	578_W	0.504	0.86
562_A	583_K	0.504	0.86
454_H	472_E	0.503	0.86
36_T	40_I	0.502	0.86
282_E	292_I	0.502	0.86
65_L	303_V	0.502	0.86
44_Q	47_P	0.501	0.86
93_I	209_G	0.500	0.86

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4oonA	1	0.5514	100	0.144	Contact Map
3vmaA	1	0.8683	100	0.19	Contact Map
2jchA	1	0.6035	100	0.199	Contact Map
3udfA	2	0.699	100	0.207	Contact Map
2olvA	1	0.8321	100	0.254	Contact Map
3zg9B	1	0.6281	100	0.408	Contact Map
2y2mA	2	0.6411	100	0.566	Contact Map
3un7A	1	0.5166	100	0.631	Contact Map
2v2fF	1	0.4978	100	0.632	Contact Map
2oqoA	2	0.2619	100	0.649	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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