GREMLIN Database
RL331 - 50S ribosomal protein L33 1
UniProt: P56849 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 49 (49)
Sequences: 407 (122)
Seq/√Len: 17.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
14_E38_R5.8361.00
4_N18_I2.5440.96
12_C36_C1.9950.87
35_Y40_K1.8750.84
33_K41_K1.8420.83
1_M23_K1.6830.76
11_E41_K1.6730.76
13_G42_S1.5880.72
14_E39_D1.5720.71
8_A15_R1.5490.70
26_N30_V1.4900.67
4_N20_K1.4120.63
12_C39_D1.3840.61
3_V23_K1.3090.57
20_K25_N1.1830.49
26_N29_R1.1690.48
39_D42_S1.1140.45
33_K44_L1.1130.45
5_I32_F1.0740.42
26_N32_F1.0690.42
29_R46_R1.0440.41
8_A37_P1.0290.40
10_T31_E1.0100.39
1_M4_N0.9780.37
5_I19_S0.9730.37
13_G38_R0.9470.35
36_C39_D0.9370.35
13_G39_D0.9220.34
32_F35_Y0.9010.33
25_N30_V0.8800.32
24_R27_P0.8710.31
41_K49_K0.8670.31
15_R48_T0.8660.31
8_A27_P0.8640.31
2_R6_T0.8590.30
2_R8_A0.8490.30
32_F46_R0.8430.30
3_V49_K0.8250.29
11_E44_L0.8200.28
21_K47_E0.8050.28
22_N30_V0.7960.27
3_V18_I0.7850.27
35_Y43_T0.7790.26
5_I30_V0.7780.26
24_R48_T0.7650.26
19_S48_T0.7150.24
7_L28_D0.7130.24
4_N46_R0.7110.23
25_N32_F0.7100.23
19_S30_V0.6950.23
6_T48_T0.6880.22
1_M24_R0.6660.22
6_T18_I0.6520.21
10_T46_R0.6520.21
22_N32_F0.6470.21
11_E40_K0.6410.21
29_R37_P0.6410.21
22_N26_N0.6090.19
10_T44_L0.5990.19
20_K26_N0.5990.19
13_G43_T0.5980.19
2_R28_D0.5900.19
15_R29_R0.5740.18
14_E42_S0.5670.18
8_A35_Y0.5500.17
15_R31_E0.5370.17
38_R42_S0.5360.17
4_N14_E0.5310.17
38_R49_K0.5300.16
6_T44_L0.5280.16
33_K39_D0.5250.16
33_K46_R0.5190.16
4_N28_D0.5110.16
16_N39_D0.5000.16
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1nkw1 1 1 99.8 0.184 Contact Map
4rb66 1 1 99.8 0.192 Contact Map
3bbo3 1 1 99.8 0.197 Contact Map
4tp91 1 1 99.8 0.198 Contact Map
2zjr1 1 1 99.8 0.203 Contact Map
3j7y1 1 0.9592 99.8 0.263 Contact Map
1vw4X 1 0.9592 99.7 0.275 Contact Map
3j21j 1 0.4898 82.8 0.819 Contact Map
1vq83 1 0.4898 82.5 0.82 Contact Map
4a18C 1 0.4898 76.5 0.83 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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