LCTP - BACSU - GREMLIN Contacts

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LCTP - L-lactate permease

UniProt:	P55910	Sequences: MWEQLYDPFGNEYVSALVALTPILFFLLALTVLKMKGILAAFLTLAVSFFVSVWAFHMPVEKAISSVLLGIGSGLWPIGYIVLMAVWLYKIAVKTGKFTIIRSSIAGISPDQRLQLLLIGFCFNAFLEGAAGFGVPIAISAALLVELGFKPLKAAALCLIANAASGAFGAIGIPVITGAQIGDLSALELSRTLMWTLPMISFLIPFLLVFLLDRMKGIKQTWPALLVVSGGYTAVQTLTMAVLGPELANILAALFSMGGLALFLRKWQPKEIYREEGAGDAGEKKAYRAADIAKAWSPFYILTAAITIWSLPAFKALFQEGGLLYQSTLLFKMPFLHQQIMKMPPIAPSAMPLDAVFKVDLLSATGTAILAAVIVTGLFSKKFSSRDAFASLKETGKELWVPIMTICFVMGFANLANFAGLSSSIGLALAKTGDLFPFVSPVLGWIGVFITGSVVSNNALFGHLQVVTGAQIGAGSDLLLAANTAGGVMAKLVSPQSIAIAAAAVGQTGKESKLFKRTVAYSLILLLIICIWTFILARLGV	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	541 (502)
Sequences:	1583 (999)
Seq/√Len:	44.6

ECOLI - GLCA LLDP
BACSU - LCTP LUTP
HALSA - Q9HHI2
SULSO - Q7LX72

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
510_K	513_K	6.410	1.00
50_F	54_W	5.021	1.00
25_F	47_V	4.702	1.00
436_F	440_S	4.529	1.00
482_A	533_T	4.318	1.00
262_L	266_K	4.033	1.00
397_K	400_W	3.887	1.00
53_V	63_A	3.864	1.00
235_V	255_F	3.720	1.00
49_F	63_A	3.575	1.00
374_I	378_L	3.573	1.00
227_V	263_F	3.407	1.00
220_Q	271_E	3.403	1.00
442_V	526_L	3.235	1.00
178_G	462_G	3.156	1.00
393_K	397_K	3.144	1.00
28_L	33_L	3.088	1.00
49_F	415_L	3.078	1.00
95_T	383_F	2.974	1.00
122_C	256_S	2.968	1.00
109_S	114_L	2.959	1.00
526_L	530_C	2.877	1.00
45_L	67_V	2.853	1.00
25_F	29_A	2.846	1.00
94_K	394_E	2.843	1.00
160_I	211_L	2.816	1.00
71_I	407_C	2.686	1.00
90_K	398_E	2.633	1.00
195_W	241_A	2.627	1.00
474_A	479_L	2.583	1.00
376_T	380_S	2.572	1.00
213_D	217_G	2.561	1.00
51_V	55_A	2.560	1.00
18_V	55_A	2.544	1.00
94_K	387_D	2.336	1.00
35_M	39_L	2.280	1.00
305_A	371_A	2.273	1.00
372_A	376_T	2.192	1.00
231_G	259_G	2.177	1.00
155_A	501_A	2.136	1.00
287_Y	291_D	2.133	1.00
290_A	294_K	2.128	1.00
531_I	535_I	2.123	1.00
145_V	505_V	2.094	0.99
442_V	530_C	2.093	0.99
462_G	480_L	2.083	0.99
386_R	390_A	2.081	0.99
175_V	193_L	2.077	0.99
293_A	297_S	2.073	0.99
195_W	237_T	2.072	0.99
234_A	238_L	2.068	0.99
466_V	480_L	2.067	0.99
192_T	477_D	2.065	0.99
46_A	50_F	2.060	0.99
297_S	379_F	2.014	0.99
377_G	388_A	2.008	0.99
527_L	531_I	1.986	0.99
416_A	422_S	1.971	0.99
384_S	387_D	1.957	0.99
251_L	255_F	1.954	0.99
294_K	382_K	1.946	0.99
389_F	393_K	1.933	0.99
178_G	480_L	1.909	0.99
99_T	102_R	1.893	0.99
28_L	32_V	1.877	0.99
223_P	267_W	1.856	0.99
309_W	368_A	1.837	0.99
315_K	319_Q	1.836	0.99
202_F	233_T	1.833	0.99
385_S	389_F	1.810	0.98
231_G	256_S	1.781	0.98
209_V	221_T	1.774	0.98
88_L	373_V	1.766	0.98
166_G	454_V	1.759	0.98
314_F	317_L	1.756	0.98
94_K	390_A	1.755	0.98
258_G	262_L	1.750	0.98
68_L	341_M	1.748	0.98
16_A	428_A	1.743	0.98
36_K	40_A	1.715	0.98
120_G	208_L	1.692	0.98
455_V	490_A	1.683	0.98
293_A	300_Y	1.682	0.98
491_K	497_S	1.680	0.98
42_F	408_F	1.679	0.98
167_A	193_L	1.662	0.97
206_F	225_L	1.657	0.97
176_I	245_P	1.653	0.97
29_A	43_L	1.637	0.97
114_L	224_A	1.635	0.97
79_G	403_I	1.634	0.97
29_A	35_M	1.631	0.97
239_T	251_L	1.626	0.97
231_G	255_F	1.619	0.97
194_M	240_M	1.616	0.97
288_R	291_D	1.612	0.97
179_A	184_L	1.609	0.97
330_L	358_K	1.607	0.97
40_A	126_F	1.604	0.97
203_L	206_F	1.555	0.96
116_L	157_L	1.550	0.96
237_T	242_V	1.548	0.96
291_D	294_K	1.542	0.96
238_L	242_V	1.537	0.96
202_F	229_S	1.533	0.96
196_T	532_W	1.517	0.95
454_V	487_G	1.512	0.95
104_S	296_W	1.512	0.95
445_W	522_S	1.484	0.95
124_N	161_A	1.466	0.95
184_L	477_D	1.466	0.95
127_L	135_V	1.462	0.94
228_V	260_L	1.461	0.94
193_L	485_A	1.440	0.94
163_A	492_L	1.435	0.94
178_G	189_L	1.427	0.94
103_S	287_Y	1.414	0.93
222_W	225_L	1.411	0.93
90_K	395_T	1.403	0.93
66_S	69_L	1.397	0.93
185_S	188_E	1.392	0.93
18_V	21_T	1.376	0.92
196_T	536_L	1.372	0.92
112_Q	275_E	1.368	0.92
69_L	418_F	1.367	0.92
191_R	241_A	1.364	0.92
120_G	124_N	1.362	0.92
179_A	186_A	1.353	0.92
43_L	46_A	1.351	0.92
273_Y	276_E	1.344	0.92
156_A	517_R	1.340	0.91
498_I	515_F	1.329	0.91
534_F	538_R	1.325	0.91
235_V	252_A	1.323	0.91
502_A	514_L	1.318	0.91
371_A	375_V	1.316	0.91
145_V	507_Q	1.307	0.90
194_M	241_A	1.304	0.90
117_L	228_V	1.302	0.90
449_F	518_T	1.300	0.90
133_F	453_S	1.298	0.90
120_G	161_A	1.287	0.90
489_M	525_L	1.287	0.90
88_L	302_L	1.280	0.89
438_F	527_L	1.278	0.89
87_W	373_V	1.275	0.89
135_V	512_S	1.270	0.89
134_G	169_G	1.265	0.89
156_A	514_L	1.259	0.89
53_V	60_V	1.250	0.88
170_A	173_I	1.235	0.88
223_P	269_P	1.233	0.88
230_G	374_I	1.231	0.87
115_Q	147_L	1.230	0.87
520_A	524_I	1.221	0.87
44_T	412_F	1.221	0.87
197_L	236_Q	1.219	0.87
235_V	251_L	1.213	0.87
383_F	387_D	1.212	0.87
133_F	455_V	1.212	0.87
21_T	47_V	1.190	0.86
196_T	485_A	1.187	0.85
203_L	524_I	1.187	0.85
224_A	263_F	1.183	0.85
181_I	459_A	1.180	0.85
432_T	435_L	1.165	0.84
173_I	176_I	1.164	0.84
435_L	438_F	1.157	0.84
54_W	57_H	1.152	0.84
120_G	193_L	1.152	0.84
93_V	99_T	1.152	0.84
332_K	356_V	1.150	0.84
227_V	259_G	1.148	0.83
237_T	241_A	1.139	0.83
462_G	466_V	1.137	0.83
116_L	212_L	1.135	0.83
274_R	278_A	1.134	0.83
17_L	21_T	1.131	0.83
64_I	67_V	1.130	0.82
119_I	140_S	1.127	0.82
152_L	300_Y	1.126	0.82
65_S	333_M	1.126	0.82
81_I	170_A	1.122	0.82
125_A	165_S	1.121	0.82
206_F	226_L	1.116	0.82
112_Q	149_F	1.115	0.82
42_F	404_M	1.112	0.81
263_F	267_W	1.111	0.81
175_V	189_L	1.109	0.81
54_W	60_V	1.104	0.81
438_F	534_F	1.102	0.81
177_T	180_Q	1.100	0.81
90_K	394_E	1.099	0.81
152_L	517_R	1.096	0.81
305_A	372_A	1.095	0.80
416_A	421_L	1.094	0.80
73_S	414_N	1.093	0.80
360_D	363_S	1.091	0.80
313_A	317_L	1.089	0.80
314_F	318_F	1.088	0.80
297_S	300_Y	1.085	0.80
207_L	521_Y	1.083	0.80
95_T	171_I	1.081	0.80
167_A	454_V	1.081	0.80
122_C	257_M	1.080	0.80
340_I	355_A	1.080	0.80
232_Y	249_N	1.080	0.80
443_L	464_L	1.079	0.79
493_V	519_V	1.074	0.79
65_S	68_L	1.072	0.79
72_G	357_F	1.068	0.79
210_F	218_I	1.067	0.79
200_I	528_I	1.067	0.79
112_Q	274_R	1.065	0.79
329_L	362_L	1.063	0.78
84_M	392_L	1.052	0.78
133_F	170_A	1.052	0.78
142_A	428_A	1.049	0.77
177_T	425_I	1.040	0.77
242_V	475_G	1.030	0.76
117_L	225_L	1.029	0.76
25_F	44_T	1.028	0.76
410_M	464_L	1.028	0.76
51_V	56_F	1.023	0.76
310_S	363_S	1.023	0.76
213_D	218_I	1.021	0.76
398_E	402_P	1.017	0.75
188_E	477_D	1.014	0.75
437_P	530_C	1.012	0.75
163_A	454_V	1.010	0.75
166_G	492_L	1.009	0.75
373_V	388_A	1.008	0.75
95_T	380_S	1.007	0.75
186_A	190_S	1.006	0.74
126_F	130_A	1.003	0.74
527_L	530_C	1.003	0.74
317_L	329_L	0.995	0.74
423_S	467_V	0.992	0.73
361_L	364_A	0.987	0.73
96_G	154_A	0.986	0.73
69_L	414_N	0.986	0.73
126_F	303_T	0.981	0.73
67_V	415_L	0.981	0.73
56_F	424_S	0.981	0.73
391_S	394_E	0.980	0.72
377_G	382_K	0.977	0.72
87_W	388_A	0.976	0.72
294_K	297_S	0.973	0.72
45_L	131_A	0.970	0.72
447_G	457_N	0.965	0.71
245_P	260_L	0.962	0.71
386_R	527_L	0.962	0.71
177_T	459_A	0.962	0.71
71_I	411_G	0.960	0.71
91_I	391_S	0.960	0.71
117_L	260_L	0.959	0.71
189_L	480_L	0.959	0.71
520_A	523_L	0.958	0.71
486_G	490_A	0.958	0.71
301_I	372_A	0.952	0.70
34_K	513_K	0.948	0.70
245_P	248_A	0.947	0.70
469_G	492_L	0.945	0.70
100_I	287_Y	0.934	0.69
472_I	479_L	0.933	0.69
225_L	229_S	0.925	0.68
491_K	496_Q	0.924	0.68
114_L	471_Q	0.923	0.68
494_S	499_A	0.921	0.68
308_I	314_F	0.919	0.68
333_M	481_A	0.917	0.67
369_I	495_P	0.915	0.67
458_N	484_T	0.914	0.67
110_P	272_I	0.911	0.67
115_Q	149_F	0.910	0.67
513_K	516_K	0.907	0.67
49_F	53_V	0.906	0.66
483_N	491_K	0.903	0.66
165_S	454_V	0.903	0.66
195_W	536_L	0.902	0.66
126_F	369_I	0.900	0.66
297_S	301_I	0.900	0.66
81_I	173_I	0.900	0.66
199_M	532_W	0.892	0.65
231_G	235_V	0.890	0.65
444_G	461_F	0.888	0.65
119_I	147_L	0.887	0.65
202_F	230_G	0.887	0.65
112_Q	273_Y	0.884	0.65
213_D	219_K	0.882	0.64
223_P	263_F	0.882	0.64
339_Q	354_D	0.880	0.64
64_I	531_I	0.880	0.64
80_Y	367_T	0.880	0.64
198_P	233_T	0.879	0.64
163_A	488_V	0.876	0.64
463_H	466_V	0.875	0.64
167_A	488_V	0.874	0.64
170_A	453_S	0.872	0.63
417_N	456_S	0.870	0.63
71_I	75_L	0.869	0.63
50_F	57_H	0.869	0.63
79_G	406_I	0.865	0.63
120_G	229_S	0.865	0.63
78_I	168_F	0.864	0.63
26_F	44_T	0.862	0.63
161_A	208_L	0.861	0.62
126_F	245_P	0.860	0.62
236_Q	454_V	0.858	0.62
164_A	249_N	0.857	0.62
196_T	199_M	0.857	0.62
125_A	161_A	0.856	0.62
191_R	237_T	0.855	0.62
121_F	252_A	0.854	0.62
30_L	34_K	0.853	0.62
500_I	521_Y	0.850	0.61
35_M	43_L	0.849	0.61
126_F	302_L	0.849	0.61
66_S	418_F	0.845	0.61
238_L	528_I	0.844	0.61
44_T	86_V	0.842	0.61
392_L	396_G	0.842	0.61
301_I	379_F	0.837	0.60
127_L	413_A	0.835	0.60
78_I	133_F	0.834	0.60
491_K	500_I	0.832	0.60
63_A	72_G	0.831	0.60
100_I	291_D	0.830	0.60
14_V	55_A	0.830	0.60
442_V	523_L	0.829	0.59
427_L	471_Q	0.828	0.59
90_K	391_S	0.825	0.59
437_P	472_I	0.825	0.59
308_I	318_F	0.824	0.59
225_L	230_G	0.821	0.59
131_A	135_V	0.819	0.59
31_T	116_L	0.819	0.59
426_G	467_V	0.814	0.58
178_G	459_A	0.814	0.58
187_L	190_S	0.812	0.58
262_L	284_K	0.812	0.58
23_I	129_G	0.811	0.58
265_R	286_A	0.809	0.58
246_E	310_S	0.808	0.58
165_S	193_L	0.806	0.57
206_F	222_W	0.806	0.57
216_K	271_E	0.804	0.57
54_W	283_E	0.804	0.57
163_A	166_G	0.803	0.57
394_E	397_K	0.800	0.57
115_Q	402_P	0.799	0.57
128_E	169_G	0.797	0.56
118_L	264_L	0.797	0.56
53_V	258_G	0.794	0.56
214_R	424_S	0.789	0.56
121_F	248_A	0.789	0.56
34_K	40_A	0.788	0.56
384_S	470_A	0.787	0.56
68_L	280_D	0.787	0.56
528_I	532_W	0.787	0.56
27_L	194_M	0.787	0.56
306_I	309_W	0.784	0.55
190_S	245_P	0.783	0.55
83_L	396_G	0.783	0.55
95_T	480_L	0.782	0.55
230_G	234_A	0.781	0.55
130_A	170_A	0.780	0.55
84_M	178_G	0.780	0.55
124_N	208_L	0.780	0.55
469_G	474_A	0.779	0.55
18_V	51_V	0.778	0.55
126_F	498_I	0.777	0.55
445_W	526_L	0.776	0.54
190_S	405_T	0.776	0.54
428_A	431_K	0.774	0.54
24_L	28_L	0.774	0.54
161_A	165_S	0.773	0.54
189_L	466_V	0.773	0.54
144_L	211_L	0.772	0.54
170_A	175_V	0.771	0.54
265_R	280_D	0.771	0.54
50_F	61_E	0.770	0.54
47_V	50_F	0.768	0.54
299_F	369_I	0.764	0.53
280_D	308_I	0.763	0.53
278_A	281_A	0.761	0.53
29_A	299_F	0.760	0.53
26_F	143_L	0.760	0.53
209_V	225_L	0.760	0.53
43_L	463_H	0.758	0.53
150_K	275_E	0.756	0.53
288_R	527_L	0.753	0.52
473_G	476_S	0.753	0.52
15_S	55_A	0.748	0.52
67_V	411_G	0.744	0.51
454_V	485_A	0.742	0.51
527_L	535_I	0.741	0.51
62_K	66_S	0.741	0.51
66_S	341_M	0.740	0.51
243_L	251_L	0.740	0.51
371_A	385_S	0.739	0.51
127_L	139_I	0.737	0.51
274_R	277_G	0.734	0.50
135_V	455_V	0.730	0.50
147_L	481_A	0.728	0.50
236_Q	488_V	0.728	0.50
149_F	437_P	0.727	0.50
385_S	390_A	0.726	0.50
175_V	458_N	0.724	0.49
404_M	408_F	0.723	0.49
159_L	492_L	0.722	0.49
285_K	289_A	0.722	0.49
197_L	201_S	0.718	0.49
183_D	199_M	0.717	0.49
198_P	237_T	0.717	0.49
382_K	390_A	0.715	0.49
453_S	456_S	0.714	0.48
513_K	517_R	0.714	0.48
207_L	473_G	0.713	0.48
128_E	134_G	0.713	0.48
172_G	244_G	0.712	0.48
300_Y	304_A	0.709	0.48
101_I	296_W	0.709	0.48
239_T	255_F	0.708	0.48
284_K	510_K	0.708	0.48
102_R	143_L	0.706	0.48
231_G	493_V	0.706	0.48
52_S	415_L	0.706	0.48
132_G	169_G	0.705	0.48
294_K	375_V	0.705	0.48
301_I	375_V	0.704	0.48
177_T	450_I	0.703	0.47
305_A	375_V	0.699	0.47
31_T	512_S	0.698	0.47
20_L	425_I	0.698	0.47
117_L	217_G	0.698	0.47
484_T	488_V	0.697	0.47
66_S	442_V	0.696	0.47
299_F	333_M	0.695	0.47
302_L	367_T	0.694	0.47
140_S	252_A	0.694	0.47
186_A	239_T	0.694	0.47
74_G	405_T	0.694	0.47
425_I	450_I	0.693	0.46
385_S	438_F	0.692	0.46
255_F	259_G	0.692	0.46
167_A	236_Q	0.691	0.46
386_R	389_F	0.690	0.46
47_V	428_A	0.690	0.46
304_A	389_F	0.690	0.46
378_L	385_S	0.690	0.46
413_A	456_S	0.689	0.46
258_G	270_K	0.689	0.46
74_G	199_M	0.688	0.46
105_I	490_A	0.688	0.46
175_V	484_T	0.687	0.46
129_G	530_C	0.687	0.46
436_F	472_I	0.684	0.46
144_L	226_L	0.683	0.45
135_V	421_L	0.683	0.45
488_V	496_Q	0.681	0.45
108_I	152_L	0.681	0.45
299_F	413_A	0.680	0.45
454_V	491_K	0.678	0.45
46_A	188_E	0.678	0.45
93_V	102_R	0.677	0.45
133_F	169_G	0.676	0.45
41_A	160_I	0.675	0.45
485_A	536_L	0.674	0.45
405_T	487_G	0.674	0.45
168_F	248_A	0.674	0.45
80_Y	366_G	0.673	0.45
49_F	64_I	0.673	0.45
300_Y	527_L	0.672	0.44
154_A	296_W	0.672	0.44
302_L	412_F	0.672	0.44
523_L	527_L	0.670	0.44
205_P	483_N	0.669	0.44
436_F	518_T	0.668	0.44
384_S	438_F	0.666	0.44
110_P	253_A	0.666	0.44
46_A	144_L	0.664	0.44
115_Q	430_A	0.663	0.44
20_L	24_L	0.662	0.43
229_S	233_T	0.662	0.43
287_Y	292_I	0.661	0.43
126_F	158_C	0.660	0.43
267_W	270_K	0.659	0.43
95_T	443_L	0.658	0.43
376_T	383_F	0.658	0.43
283_E	374_I	0.655	0.43
495_P	499_A	0.655	0.43
45_L	49_F	0.655	0.43
401_V	404_M	0.654	0.43
266_K	270_K	0.652	0.43
156_A	518_T	0.649	0.42
119_I	123_F	0.649	0.42
248_A	252_A	0.648	0.42
387_D	390_A	0.646	0.42
454_V	458_N	0.646	0.42
125_A	448_V	0.645	0.42
56_F	296_W	0.645	0.42
259_G	396_G	0.645	0.42
177_T	181_I	0.645	0.42
206_F	472_I	0.644	0.42
129_G	163_A	0.644	0.42
21_T	51_V	0.644	0.42
486_G	493_V	0.643	0.42
198_P	249_N	0.643	0.42
155_A	464_L	0.643	0.42
188_E	192_T	0.641	0.41
332_K	375_V	0.639	0.41
275_E	278_A	0.638	0.41
56_F	398_E	0.638	0.41
36_K	39_L	0.638	0.41
75_L	340_I	0.636	0.41
167_A	175_V	0.636	0.41
285_K	385_S	0.635	0.41
129_G	296_W	0.634	0.41
17_L	331_F	0.634	0.41
166_G	455_V	0.634	0.41
278_A	371_A	0.633	0.41
192_T	478_L	0.632	0.41
432_T	439_V	0.631	0.41
167_A	484_T	0.628	0.40
81_I	88_L	0.628	0.40
449_F	498_I	0.627	0.40
389_F	397_K	0.624	0.40
59_P	222_W	0.624	0.40
226_L	230_G	0.622	0.40
237_T	249_N	0.621	0.40
437_P	534_F	0.620	0.40
286_A	531_I	0.619	0.39
454_V	488_V	0.618	0.39
170_A	174_P	0.618	0.39
352_P	523_L	0.617	0.39
162_N	496_Q	0.617	0.39
198_P	201_S	0.616	0.39
24_L	226_L	0.616	0.39
474_A	538_R	0.615	0.39
277_G	288_R	0.615	0.39
102_R	486_G	0.614	0.39
213_D	501_A	0.614	0.39
252_A	305_A	0.613	0.39
487_G	522_S	0.611	0.39
429_L	432_T	0.610	0.39
135_V	174_P	0.610	0.39
199_M	485_A	0.610	0.39
171_I	310_S	0.610	0.39
290_A	304_A	0.609	0.39
30_L	37_G	0.609	0.39
137_I	501_A	0.609	0.39
374_I	534_F	0.608	0.38
306_I	369_I	0.607	0.38
86_V	299_F	0.607	0.38
116_L	120_G	0.606	0.38
276_E	280_D	0.606	0.38
86_V	369_I	0.605	0.38
406_I	497_S	0.605	0.38
19_A	232_Y	0.605	0.38
101_I	449_F	0.603	0.38
84_M	369_I	0.603	0.38
422_S	450_I	0.603	0.38
202_F	477_D	0.602	0.38
438_F	441_P	0.602	0.38
400_W	404_M	0.601	0.38
129_G	306_I	0.600	0.38
456_S	459_A	0.600	0.38
152_L	370_L	0.599	0.38
172_G	197_L	0.598	0.38
190_S	234_A	0.597	0.37
218_I	308_I	0.596	0.37
258_G	300_Y	0.596	0.37
483_N	496_Q	0.595	0.37
29_A	231_G	0.595	0.37
44_T	48_S	0.595	0.37
120_G	489_M	0.595	0.37
81_I	254_L	0.594	0.37
23_I	449_F	0.592	0.37
24_L	300_Y	0.591	0.37
413_A	495_P	0.590	0.37
192_T	195_W	0.590	0.37
83_L	114_L	0.589	0.37
87_W	392_L	0.588	0.37
422_S	459_A	0.588	0.37
113_R	205_P	0.587	0.37
60_V	329_L	0.586	0.36
380_S	383_F	0.585	0.36
97_K	292_I	0.584	0.36
228_V	231_G	0.584	0.36
57_H	374_I	0.583	0.36
182_G	480_L	0.582	0.36
64_I	188_E	0.581	0.36
170_A	501_A	0.581	0.36
47_V	51_V	0.581	0.36
246_E	365_T	0.580	0.36
164_A	488_V	0.580	0.36
413_A	512_S	0.579	0.36
223_P	227_V	0.578	0.36
433_G	439_V	0.578	0.36
195_W	240_M	0.578	0.36
276_E	283_E	0.578	0.36
100_I	292_I	0.578	0.36
64_I	276_E	0.578	0.36
179_A	189_L	0.575	0.35
176_I	240_M	0.574	0.35
150_K	153_K	0.574	0.35
27_L	513_K	0.573	0.35
277_G	359_V	0.571	0.35
120_G	186_A	0.571	0.35
280_D	283_E	0.570	0.35
171_I	459_A	0.569	0.35
397_K	527_L	0.568	0.35
116_L	439_V	0.567	0.35
279_G	282_G	0.565	0.35
454_V	492_L	0.565	0.35
86_V	101_I	0.564	0.34
242_V	375_V	0.563	0.34
152_L	156_A	0.562	0.34
124_N	162_N	0.562	0.34
18_V	175_V	0.562	0.34
500_I	512_S	0.562	0.34
420_G	535_I	0.562	0.34
124_N	164_A	0.559	0.34
519_V	524_I	0.559	0.34
485_A	488_V	0.558	0.34
130_A	173_I	0.556	0.34
270_K	462_G	0.556	0.34
124_N	165_S	0.555	0.34
122_C	260_L	0.554	0.34
427_L	464_L	0.553	0.34
129_G	486_G	0.552	0.33
285_K	393_K	0.552	0.33
183_D	290_A	0.551	0.33
252_A	301_I	0.551	0.33
48_S	51_V	0.550	0.33
83_L	230_G	0.548	0.33
17_L	24_L	0.548	0.33
53_V	64_I	0.547	0.33
37_G	102_R	0.547	0.33
340_I	353_L	0.546	0.33
277_G	280_D	0.546	0.33
30_L	370_L	0.546	0.33
169_G	453_S	0.546	0.33
405_T	426_G	0.545	0.33
496_Q	500_I	0.545	0.33
108_I	304_A	0.545	0.33
418_F	426_G	0.545	0.33
103_S	285_K	0.544	0.33
425_I	500_I	0.544	0.33
409_V	494_S	0.544	0.33
384_S	389_F	0.543	0.33
416_A	495_P	0.543	0.33
83_L	87_W	0.542	0.33
107_G	263_F	0.541	0.33
21_T	379_F	0.541	0.33
456_S	495_P	0.540	0.32
77_P	518_T	0.540	0.32
41_A	409_V	0.539	0.32
55_A	68_L	0.539	0.32
68_L	378_L	0.539	0.32
308_I	439_V	0.538	0.32
154_A	411_G	0.538	0.32
483_N	500_I	0.538	0.32
86_V	135_V	0.537	0.32
409_V	496_Q	0.537	0.32
34_K	93_V	0.537	0.32
240_M	248_A	0.536	0.32
283_E	304_A	0.536	0.32
24_L	43_L	0.536	0.32
177_T	294_K	0.535	0.32
50_F	278_A	0.534	0.32
283_E	332_K	0.534	0.32
122_C	228_V	0.534	0.32
235_V	239_T	0.534	0.32
191_R	300_Y	0.534	0.32
53_V	400_W	0.533	0.32
472_I	534_F	0.533	0.32
411_G	460_L	0.532	0.32
239_T	243_L	0.531	0.32
125_A	162_N	0.530	0.32
85_A	131_A	0.530	0.32
423_S	427_L	0.530	0.32
415_L	426_G	0.529	0.31
143_L	318_F	0.528	0.31
242_V	266_K	0.528	0.31
194_M	236_Q	0.527	0.31
197_L	454_V	0.527	0.31
60_V	258_G	0.527	0.31
319_Q	363_S	0.526	0.31
86_V	171_I	0.526	0.31
504_A	514_L	0.526	0.31
199_M	238_L	0.525	0.31
32_V	54_W	0.525	0.31
216_K	219_K	0.524	0.31
252_A	485_A	0.521	0.31
432_T	514_L	0.520	0.31
230_G	394_E	0.520	0.31
80_Y	311_L	0.520	0.31
212_L	275_E	0.520	0.31
134_G	366_G	0.520	0.31
27_L	51_V	0.520	0.31
126_F	207_L	0.519	0.31
86_V	103_S	0.518	0.31
117_L	122_C	0.518	0.31
191_R	194_M	0.517	0.30
183_D	411_G	0.517	0.30
155_A	514_L	0.517	0.30
441_P	495_P	0.517	0.30
223_P	266_K	0.516	0.30
122_C	125_A	0.516	0.30
237_T	532_W	0.516	0.30
162_N	491_K	0.516	0.30
68_L	301_I	0.515	0.30
226_L	265_R	0.515	0.30
454_V	484_T	0.515	0.30
230_G	235_V	0.514	0.30
157_L	518_T	0.514	0.30
457_N	488_V	0.514	0.30
492_L	507_Q	0.514	0.30
37_G	44_T	0.513	0.30
319_Q	440_S	0.513	0.30
282_G	523_L	0.511	0.30
466_V	470_A	0.511	0.30
187_L	191_R	0.510	0.30
386_R	431_K	0.510	0.30
185_S	280_D	0.510	0.30
135_V	364_A	0.509	0.30
46_A	49_F	0.508	0.30
112_Q	276_E	0.508	0.30
57_H	60_V	0.508	0.30
161_A	236_Q	0.508	0.30
390_A	393_K	0.508	0.30
406_I	500_I	0.506	0.30
353_L	450_I	0.506	0.30
35_M	40_A	0.506	0.30
127_L	170_A	0.505	0.30
45_L	415_L	0.505	0.30
432_T	440_S	0.505	0.30
113_R	220_Q	0.504	0.29
160_I	504_A	0.504	0.29
157_L	361_L	0.503	0.29
250_I	438_F	0.503	0.29
430_A	464_L	0.503	0.29
115_Q	302_L	0.503	0.29
46_A	332_K	0.503	0.29
342_K	353_L	0.502	0.29
14_V	23_I	0.501	0.29
80_Y	370_L	0.501	0.29
498_I	533_T	0.501	0.29
206_F	231_G	0.500	0.29
136_P	497_S	0.500	0.29
285_K	375_V	0.500	0.29

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4r0cA	3	0.8281	99.8	0.87	Contact Map
4r1iA	2	0.8262	99.7	0.878	Contact Map
4f35D	2	0.7357	99.7	0.88	Contact Map
3qe7A	2	0.4566	21.5	0.979	Contact Map
3qnqA	2	0.5046	15.7	0.981	Contact Map
2m20A	2	0.0906	12.7	0.981	Contact Map
2m67A	1	0.1238	6.1	0.984	Contact Map
4x5mA	2	0.1664	4.3	0.985	Contact Map
2xq2A	2	0.3198	3.9	0.985	Contact Map
2gfpA	2	0.6026	3.9	0.985	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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