GREMLIN Database
YBAS - Uncharacterized protein YbaS
UniProt: P55190 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 306 (290)
Sequences: 6028 (3561)
Seq/√Len: 209.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
35_F167_F7.0621.00
111_N244_E6.8411.00
233_L237_M3.6441.00
35_F163_L3.0981.00
105_A110_G3.0711.00
47_R51_S3.0621.00
145_D148_G3.0021.00
242_Q246_V2.9681.00
236_K245_I2.7441.00
241_R244_E2.7261.00
89_L219_T2.6351.00
224_A286_L2.4571.00
63_L97_T2.4321.00
260_G276_V2.4021.00
235_G245_I2.3151.00
8_S192_M2.2891.00
174_E178_F2.1431.00
235_G248_L2.1391.00
4_L8_S2.1291.00
91_L264_A2.1231.00
61_F65_I2.1201.00
44_Q47_R2.1191.00
16_S20_N2.1171.00
4_L16_S2.1171.00
64_H129_I2.1001.00
45_S48_H2.0681.00
94_V133_S2.0291.00
70_F226_T1.9941.00
72_W76_H1.9481.00
232_W245_I1.9281.00
71_A93_V1.8921.00
162_F166_L1.8861.00
104_W250_F1.8841.00
229_A233_L1.8791.00
57_I61_F1.8631.00
214_A218_V1.8621.00
78_I219_T1.8501.00
115_T247_S1.8491.00
240_R248_L1.8381.00
67_M227_G1.8181.00
9_V16_S1.8071.00
221_F282_F1.7971.00
48_H51_S1.7941.00
7_T11_L1.7781.00
60_L125_L1.7761.00
69_L73_G1.7231.00
125_L129_I1.6701.00
292_Y296_R1.6591.00
8_S16_S1.6571.00
42_N168_N1.6541.00
290_F294_L1.6521.00
166_L170_M1.6451.00
282_F286_L1.6241.00
75_G86_I1.6211.00
16_S19_L1.6211.00
105_A247_S1.5891.00
73_G77_L1.5581.00
147_W151_K1.5301.00
74_S219_T1.5291.00
58_L238_M1.5101.00
105_A115_T1.5011.00
62_V231_A1.4991.00
17_Q20_N1.4841.00
15_L18_F1.4751.00
293_M297_F1.4581.00
240_R244_E1.4461.00
58_L248_L1.4361.00
6_P10_V1.4241.00
4_L7_T1.4091.00
20_N23_E1.3971.00
152_G155_V1.3891.00
95_I260_G1.3871.00
92_A279_G1.3831.00
249_I294_L1.3721.00
242_Q297_F1.3691.00
53_P57_I1.3631.00
70_F227_G1.3561.00
84_L271_Q1.3551.00
245_I249_I1.3451.00
42_N45_S1.3441.00
226_T230_A1.3301.00
111_N243_E1.3251.00
13_V16_S1.3201.00
25_A28_W1.3201.00
246_V294_L1.2851.00
5_T8_S1.2831.00
232_W242_Q1.2751.00
6_P9_V1.2741.00
168_N177_A1.2721.00
167_F171_S1.2711.00
257_I280_M1.2701.00
108_Y291_G1.2631.00
73_G76_H1.2561.00
24_W28_W1.2541.00
292_Y295_N1.2431.00
97_T119_I1.2431.00
28_W31_A1.2421.00
62_V252_G1.2251.00
154_I159_I1.2231.00
133_S137_L1.2161.00
64_H122_D1.1901.00
165_M169_Q1.1901.00
235_G240_R1.1781.00
55_P240_R1.1751.00
289_L293_M1.1621.00
8_S12_G1.1621.00
5_T9_V1.1561.00
62_V66_F1.1511.00
94_V134_L1.1491.00
221_F286_L1.1411.00
59_A118_I1.1371.00
38_S164_G1.1311.00
17_Q21_G1.1141.00
172_S176_T1.0971.00
44_Q48_H1.0921.00
172_S177_A1.0881.00
87_T138_A1.0851.00
90_T137_L1.0811.00
234_I238_M1.0801.00
34_T38_S1.0701.00
101_S255_R1.0681.00
177_A180_S1.0611.00
241_R245_I1.0591.00
11_L14_L1.0561.00
151_K155_V1.0531.00
245_I294_L1.0531.00
16_S22_Y1.0521.00
4_L192_M1.0481.00
56_M121_V1.0451.00
4_L9_V1.0431.00
18_F21_G1.0371.00
9_V12_G1.0311.00
186_F190_C1.0271.00
60_L121_V1.0261.00
10_V13_V1.0261.00
55_P114_L1.0261.00
126_S130_V1.0211.00
225_L229_A1.0061.00
85_T216_I1.0041.00
129_I132_L1.0041.00
16_S21_G0.9981.00
69_L137_L0.9951.00
117_S120_L0.9921.00
63_L255_R0.9861.00
5_T16_S0.9771.00
54_L240_R0.9751.00
250_F254_M0.9751.00
48_H117_S0.9731.00
90_T94_V0.9641.00
52_H111_N0.9631.00
6_P16_S0.9611.00
113_G116_L0.9611.00
232_W249_I0.9601.00
82_D215_G0.9581.00
98_G101_S0.9561.00
4_L20_N0.9510.99
62_V234_I0.9430.99
148_G151_K0.9410.99
203_A207_K0.9390.99
7_T10_V0.9380.99
102_L251_T0.9370.99
10_V14_L0.9310.99
25_A197_I0.9310.99
129_I133_S0.9300.99
233_L236_K0.9290.99
9_V13_V0.9280.99
144_M149_M0.9240.99
82_D86_I0.9220.99
16_S23_E0.9130.99
260_G275_P0.9030.99
91_L130_V0.9020.99
176_T180_S0.9020.99
89_L220_V0.8980.99
8_S11_L0.8960.99
76_H80_K0.8940.99
279_G284_Q0.8940.99
59_A248_L0.8930.99
19_L23_E0.8930.99
287_A291_G0.8860.99
109_K295_N0.8840.99
55_P244_E0.8840.99
191_L195_I0.8770.99
52_H244_E0.8750.99
43_F169_Q0.8730.99
81_G85_T0.8710.99
58_L240_R0.8680.99
45_S113_G0.8670.99
13_V207_K0.8650.99
155_V159_I0.8640.99
17_Q22_Y0.8630.99
19_L22_Y0.8620.99
236_K242_Q0.8580.99
225_L289_L0.8510.99
9_V17_Q0.8500.99
70_F73_G0.8450.99
61_F234_I0.8420.99
75_G90_T0.8300.99
4_L17_Q0.8300.99
29_I190_C0.8300.99
236_K239_K0.8280.99
97_T250_F0.8250.99
12_G16_S0.8210.99
174_E177_A0.8180.98
202_I205_Y0.8140.98
178_F182_A0.8130.98
179_V182_A0.8130.98
146_V150_M0.8120.98
100_T228_Y0.8100.98
196_A200_S0.8090.98
144_M148_G0.8090.98
123_T259_A0.8080.98
280_M284_Q0.8080.98
63_L115_T0.8080.98
74_S226_T0.8070.98
84_L272_V0.7960.98
20_N24_W0.7940.98
262_V266_T0.7920.98
63_L119_I0.7920.98
39_L157_V0.7890.98
12_G19_L0.7870.98
97_T118_I0.7870.98
216_I220_V0.7860.98
171_S174_E0.7830.98
82_D85_T0.7810.98
206_F212_R0.7740.98
110_G246_V0.7730.98
97_T115_T0.7720.98
80_K86_I0.7700.98
228_Y231_A0.7690.98
205_Y208_S0.7650.98
175_R179_V0.7620.98
115_T251_T0.7620.98
97_T123_T0.7590.98
228_Y290_F0.7580.97
114_L244_E0.7560.97
81_G215_G0.7550.97
8_S17_Q0.7540.97
181_S185_P0.7540.97
102_L119_I0.7530.97
32_F186_F0.7490.97
232_W297_F0.7490.97
88_G275_P0.7460.97
283_Q287_A0.7430.97
143_H147_W0.7420.97
123_T256_N0.7410.97
150_M154_I0.7410.97
122_D255_R0.7390.97
31_A163_L0.7370.97
235_G239_K0.7350.97
122_D129_I0.7340.97
166_L169_Q0.7340.97
92_A274_V0.7320.97
8_S15_L0.7270.97
242_Q245_I0.7180.97
4_L13_V0.7140.96
118_I248_L0.7130.96
46_L49_A0.7130.96
98_G251_T0.7130.96
99_I104_W0.7070.96
66_F230_A0.7070.96
78_I222_F0.7050.96
128_L132_L0.7030.96
60_L117_S0.7030.96
8_S13_V0.7020.96
13_V205_Y0.7010.96
98_G256_N0.7010.96
199_S280_M0.6990.96
232_W236_K0.6940.96
101_S115_T0.6880.96
50_L53_P0.6870.96
18_F22_Y0.6870.96
243_E247_S0.6850.95
67_M93_V0.6840.95
13_V203_A0.6820.95
29_I194_V0.6810.95
36_A187_S0.6800.95
252_G255_R0.6800.95
132_L136_L0.6740.95
11_L17_Q0.6720.95
106_A109_K0.6720.95
86_I90_T0.6720.95
265_V273_A0.6700.95
76_H86_I0.6690.95
251_T255_R0.6690.95
98_G102_L0.6680.95
8_S20_N0.6680.95
5_T195_I0.6650.95
30_F34_T0.6620.95
149_M153_L0.6620.95
104_W254_M0.6620.95
187_S194_V0.6620.95
27_P31_A0.6610.95
26_V258_S0.6610.95
279_G283_Q0.6590.94
228_Y249_I0.6590.94
150_M153_L0.6580.94
104_W198_N0.6550.94
51_S57_I0.6540.94
167_F175_R0.6530.94
26_V253_G0.6530.94
92_A283_Q0.6520.94
261_A265_V0.6520.94
132_L135_S0.6500.94
146_V149_M0.6490.94
99_I257_I0.6420.94
277_V281_L0.6420.94
116_L119_I0.6410.94
55_P248_L0.6400.94
152_G156_M0.6390.93
177_A237_M0.6390.93
104_W283_Q0.6390.93
14_L17_Q0.6370.93
63_L251_T0.6370.93
105_A261_A0.6360.93
257_I283_Q0.6350.93
108_Y250_F0.6350.93
288_A292_Y0.6340.93
211_L215_G0.6330.93
117_S121_V0.6320.93
58_L235_G0.6230.93
119_I251_T0.6210.92
75_G89_L0.6200.92
171_S175_R0.6200.92
106_A112_V0.6200.92
80_K83_P0.6170.92
63_L118_I0.6170.92
218_V221_F0.6160.92
59_A251_T0.6140.92
29_I193_A0.6100.92
100_T284_Q0.6070.92
249_I253_G0.6060.92
98_G254_M0.6050.92
95_I126_S0.6040.91
11_L15_L0.6030.91
97_T100_T0.6020.91
276_V283_Q0.6010.91
197_I201_A0.5990.91
153_L158_V0.5990.91
27_P156_M0.5960.91
55_P118_I0.5960.91
168_N172_S0.5960.91
208_S211_L0.5960.91
97_T251_T0.5960.91
95_I130_V0.5900.90
91_L263_L0.5860.90
100_T122_D0.5850.90
280_M283_Q0.5820.90
212_R216_I0.5820.90
74_S222_F0.5820.90
103_I191_L0.5810.90
87_T134_L0.5810.90
290_F293_M0.5800.90
73_G226_T0.5760.89
168_N180_S0.5750.89
126_S133_S0.5750.89
166_L217_A0.5750.89
183_L186_F0.5740.89
59_A63_L0.5740.89
55_P59_A0.5740.89
48_H52_H0.5720.89
7_T14_L0.5710.89
86_I89_L0.5710.89
13_V21_G0.5700.89
166_L171_S0.5700.89
163_L167_F0.5700.89
147_W150_M0.5700.89
60_L118_I0.5680.89
15_L20_N0.5670.89
254_M287_A0.5660.89
71_A75_G0.5650.89
111_N241_R0.5640.88
75_G78_I0.5630.88
225_L286_L0.5620.88
128_L184_S0.5570.88
191_L202_I0.5560.88
182_A185_P0.5550.88
220_V224_A0.5540.88
235_G249_I0.5540.88
18_F204_P0.5510.87
58_L234_I0.5510.87
172_S175_R0.5500.87
180_S184_S0.5500.87
228_Y287_A0.5490.87
18_F23_E0.5490.87
65_I69_L0.5480.87
230_A234_I0.5460.87
100_T254_M0.5460.87
71_A89_L0.5450.87
104_W194_V0.5440.87
74_S89_L0.5440.87
99_I260_G0.5440.87
258_S262_V0.5420.86
98_G280_M0.5410.86
273_A277_V0.5410.86
33_I38_S0.5410.86
81_G86_I0.5400.86
7_T208_S0.5380.86
6_P21_G0.5350.86
101_S247_S0.5350.86
63_L122_D0.5330.85
148_G152_G0.5320.85
87_T272_V0.5300.85
232_W246_V0.5300.85
92_A257_I0.5280.85
36_A186_F0.5270.85
85_T212_R0.5270.85
279_G285_I0.5230.84
15_L22_Y0.5210.84
34_T37_G0.5210.84
100_T283_Q0.5210.84
124_V128_L0.5200.84
33_I100_T0.5180.84
32_F36_A0.5180.84
107_M291_G0.5180.84
191_L194_V0.5160.84
102_L115_T0.5160.84
23_E201_A0.5150.84
98_G123_T0.5140.83
66_F70_F0.5130.83
91_L134_L0.5120.83
12_G15_L0.5120.83
236_K241_R0.5110.83
262_V284_Q0.5110.83
68_P255_R0.5100.83
191_L258_S0.5100.83
255_R283_Q0.5090.83
227_G253_G0.5090.83
104_W192_M0.5070.83
254_M279_G0.5050.82
74_S78_I0.5040.82
17_Q221_F0.5020.82
94_V123_T0.5020.82
4_L10_V0.5010.82
17_Q23_E0.5010.82
52_H55_P0.5000.82
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4n7wA 2 0.9771 100 0.192 Contact Map
3zuxA 1 0.9575 100 0.208 Contact Map
4czbA 2 0.9379 97.6 0.864 Contact Map
4bwzA 2 0.9542 97.2 0.872 Contact Map
4cz8A 2 0.9346 94.5 0.899 Contact Map
1zcdA 1 0.9314 74.3 0.927 Contact Map
3w4tA 1 0.9739 39.3 0.942 Contact Map
4p6vD 1 0.5817 20.3 0.949 Contact Map
1pw4A 1 0.9314 19.4 0.95 Contact Map
2m20A 2 0.1242 18 0.951 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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