GREMLIN Database
YBAR - Putative sulfate transporter YbaR
UniProt: P55189 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 478 (456)
Sequences: 7658 (4324)
Seq/√Len: 202.5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
61_F262_I4.3061.00
106_G258_R4.2641.00
141_F152_L4.0531.00
57_I266_V3.9951.00
96_I268_G3.6651.00
359_T372_V3.3741.00
97_L225_S3.0881.00
182_I186_F3.0371.00
392_S396_D3.0101.00
451_V461_A3.0031.00
358_V362_V2.9521.00
181_I185_T2.8321.00
267_T272_G2.7401.00
285_N295_S2.7371.00
22_G298_V2.6781.00
19_I298_V2.6591.00
111_A254_N2.6491.00
156_L328_M2.6201.00
179_M321_A2.5271.00
243_I282_S2.5201.00
104_I108_S2.4911.00
463_L466_L2.4171.00
365_D368_K2.3871.00
50_A275_G2.3841.00
355_V376_L2.3621.00
96_I265_I2.3491.00
398_K427_E2.3451.00
433_L436_A2.3351.00
150_A154_G2.3341.00
340_K344_K2.2891.00
14_N291_R2.2541.00
155_S324_A2.2341.00
359_T363_T2.1901.00
428_R462_E2.1581.00
15_I19_I2.1291.00
101_I222_F2.0951.00
56_I300_G2.0711.00
57_I262_I2.0611.00
399_L430_V2.0411.00
56_I297_F2.0391.00
17_K291_R2.0331.00
76_A273_M2.0071.00
105_L110_I2.0021.00
247_T286_T1.9521.00
156_L324_A1.9481.00
155_S175_A1.9481.00
75_M228_L1.9481.00
104_I107_I1.9281.00
157_V161_V1.9231.00
101_I229_A1.8941.00
337_S340_K1.8761.00
305_F309_V1.8741.00
54_I275_G1.8671.00
148_M320_A1.8601.00
451_V455_K1.8401.00
159_I175_A1.7951.00
184_V316_K1.7941.00
100_I265_I1.7711.00
266_V270_F1.7531.00
147_S150_A1.7421.00
57_I61_F1.7391.00
100_I104_I1.7321.00
15_I298_V1.7281.00
356_T373_G1.7231.00
298_V302_F1.7191.00
190_V193_V1.7151.00
420_F450_I1.7041.00
399_L428_R1.6861.00
156_L160_Y1.6831.00
28_A284_I1.6781.00
160_Y328_M1.6751.00
301_A305_F1.6701.00
181_I184_V1.6591.00
152_L324_A1.6551.00
61_F259_G1.6511.00
101_I225_S1.6511.00
134_F327_V1.6401.00
101_I226_I1.6371.00
258_R262_I1.6341.00
94_A221_I1.6301.00
354_V358_V1.6201.00
169_V174_V1.6191.00
89_Q207_L1.6171.00
191_R194_G1.6041.00
192_T195_D1.6011.00
219_Q222_F1.5981.00
26_A302_F1.5911.00
177_I181_I1.5891.00
33_A72_T1.5671.00
426_I459_I1.5621.00
99_G265_I1.5611.00
383_A387_K1.5571.00
180_T183_A1.5551.00
183_A188_V1.5541.00
413_V446_A1.5531.00
70_A281_Q1.5531.00
98_T228_L1.5391.00
131_I361_V1.5311.00
107_I258_R1.5211.00
18_D291_R1.5211.00
413_V442_S1.5071.00
153_A157_V1.5041.00
155_S179_M1.4961.00
255_K258_R1.4961.00
290_G295_S1.4861.00
15_I294_L1.4851.00
42_V273_M1.4851.00
452_A456_E1.4791.00
179_M183_A1.4611.00
23_I302_F1.4611.00
82_L224_Y1.4611.00
59_S297_F1.4591.00
130_A330_S1.4541.00
42_V83_V1.4531.00
198_N201_S1.4531.00
140_Q323_V1.4481.00
60_I297_F1.4481.00
164_R168_A1.4371.00
431_I461_A1.4281.00
146_W150_A1.4261.00
155_S321_A1.4251.00
103_V258_R1.4241.00
428_R460_E1.4231.00
53_C270_F1.4181.00
79_M274_A1.4101.00
127_N357_V1.3991.00
154_G179_M1.3891.00
141_F327_V1.3741.00
58_I69_S1.3651.00
94_A228_L1.3621.00
97_L221_I1.3551.00
95_T268_G1.3511.00
417_T449_K1.3501.00
103_V265_I1.3461.00
285_N290_G1.3451.00
407_Q437_H1.3391.00
166_T169_V1.3301.00
161_V165_F1.3291.00
217_T220_I1.3201.00
405_K435_E1.3141.00
431_I463_L1.3121.00
210_D214_T1.3101.00
360_V369_G1.3011.00
103_V107_I1.2871.00
131_I357_V1.2831.00
55_A300_G1.2741.00
141_F323_V1.2711.00
93_A218_L1.2711.00
219_Q223_P1.2681.00
106_G111_A1.2641.00
130_A334_F1.2621.00
216_E219_Q1.2591.00
468_K472_S1.2591.00
12_F16_R1.2571.00
225_S229_A1.2571.00
454_F459_I1.2511.00
154_G182_I1.2421.00
363_T368_K1.2341.00
67_M277_A1.2301.00
306_L310_L1.2291.00
114_M117_I1.2231.00
80_V84_A1.2211.00
171_S175_A1.2121.00
294_L298_V1.2021.00
335_D338_S1.2011.00
53_C266_V1.2001.00
385_I409_F1.1911.00
98_T229_A1.1681.00
214_T217_T1.1581.00
149_Y153_A1.1571.00
466_L470_S1.1451.00
297_F301_A1.1431.00
160_Y331_V1.1391.00
248_D456_E1.1381.00
151_M190_V1.1361.00
66_G286_T1.1351.00
191_R195_D1.1331.00
222_F226_I1.1301.00
239_T279_I1.1271.00
244_D251_S1.1271.00
21_A25_V1.1231.00
430_V462_E1.1201.00
206_F209_P1.1201.00
54_I267_T1.1191.00
57_I259_G1.1191.00
22_G26_A1.1111.00
233_L257_S1.1101.00
400_R426_I1.1051.00
42_V46_V1.1031.00
421_I453_K1.1011.00
390_I402_Y1.1001.00
127_N130_A1.0991.00
182_I185_T1.0981.00
419_A423_Q1.0961.00
284_I288_A1.0961.00
158_I175_A1.0951.00
371_F375_L1.0941.00
82_L94_A1.0941.00
68_I296_A1.0931.00
187_H190_V1.0901.00
343_K347_L1.0871.00
109_K112_R1.0761.00
135_S138_L1.0751.00
53_C267_T1.0741.00
59_S296_A1.0661.00
450_I461_A1.0651.00
102_Q232_G1.0651.00
30_I303_L1.0651.00
390_I419_A1.0621.00
52_F304_M1.0591.00
351_I355_V1.0581.00
106_G261_G1.0541.00
149_Y152_L1.0531.00
159_I324_A1.0511.00
154_G158_I1.0471.00
206_F270_F1.0471.00
434_T465_G1.0421.00
33_A51_S1.0411.00
150_A153_A1.0401.00
46_V88_L1.0401.00
263_A267_T1.0361.00
444_A448_D1.0341.00
152_L327_V1.0321.00
467_N470_S1.0261.00
151_M179_M1.0241.00
83_V87_G1.0231.00
18_D292_G1.0221.00
402_Y420_F1.0191.00
407_Q436_A1.0141.00
305_F308_A1.0071.00
66_G247_T1.0061.00
94_A225_S0.9991.00
58_I275_G0.9981.00
337_S341_G0.9981.00
162_L171_S0.9911.00
415_D419_A0.9891.00
52_F300_G0.9841.00
433_L466_L0.9831.00
192_T196_M0.9821.00
429_V454_F0.9801.00
48_L303_L0.9781.00
343_K350_S0.9771.00
313_V316_K0.9771.00
154_G161_V0.9761.00
453_K457_Q0.9741.00
75_M98_T0.9711.00
72_T278_M0.9650.99
416_L450_I0.9640.99
93_A97_L0.9630.99
91_L95_T0.9620.99
243_I286_T0.9610.99
387_K415_D0.9600.99
42_V91_L0.9530.99
96_I269_F0.9530.99
417_T421_I0.9510.99
381_F409_F0.9490.99
165_F168_A0.9480.99
182_I188_V0.9470.99
148_M152_L0.9450.99
69_S260_Q0.9430.99
419_A422_Y0.9400.99
437_H467_N0.9380.99
355_V359_T0.9350.99
92_F268_G0.9320.99
68_I74_S0.9320.99
244_D249_T0.9300.99
252_D255_K0.9260.99
408_I416_L0.9250.99
152_L320_A0.9250.99
216_E220_I0.9230.99
158_I178_V0.9220.99
309_V312_H0.9190.99
208_I269_F0.9180.99
368_K372_V0.9160.99
368_K371_F0.9150.99
341_G345_A0.9150.99
142_E149_Y0.9140.99
128_A361_V0.9130.99
170_P174_V0.9130.99
336_W340_K0.9110.99
105_L229_A0.9090.99
350_S354_V0.9040.99
146_W149_Y0.9030.99
173_L177_I0.9000.99
403_Q435_E0.8990.99
92_F95_T0.8870.99
190_V195_D0.8860.99
340_K343_K0.8850.99
95_T274_A0.8840.99
180_T184_V0.8830.99
300_G304_M0.8800.99
246_M283_V0.8800.99
374_V410_F0.8800.99
97_L101_I0.8790.99
348_T380_F0.8790.99
118_P377_S0.8790.99
432_D464_K0.8770.99
431_I447_L0.8760.99
99_G261_G0.8760.99
432_D465_G0.8760.99
109_K254_N0.8730.99
220_I223_P0.8720.99
174_V178_V0.8700.99
116_F409_F0.8690.99
226_I230_F0.8690.99
224_Y227_A0.8670.99
402_Y416_L0.8650.99
148_M193_V0.8620.99
16_R20_L0.8620.99
339_L353_M0.8610.99
210_D216_E0.8580.99
163_P332_G0.8560.99
294_L297_F0.8510.99
246_M286_T0.8500.99
381_F385_I0.8500.99
430_V464_K0.8490.99
334_F339_L0.8470.99
306_L314_V0.8460.99
98_T274_A0.8460.99
19_I23_I0.8440.99
355_V372_V0.8410.99
21_A288_A0.8400.99
98_T102_Q0.8390.99
154_G178_V0.8350.99
198_N315_V0.8340.98
235_E276_C0.8340.98
208_I211_V0.8340.98
21_A295_S0.8340.98
408_I436_A0.8310.98
162_L174_V0.8280.98
380_F384_K0.8280.98
355_V358_V0.8260.98
162_L165_F0.8240.98
29_L299_A0.8240.98
378_A382_V0.8230.98
239_T278_M0.8210.98
183_A186_F0.8200.98
112_R254_N0.8200.98
134_F330_S0.8190.98
102_Q233_L0.8080.98
93_A221_I0.8070.98
36_F73_G0.8060.98
120_S442_S0.8060.98
235_E279_I0.8050.98
401_T464_K0.8040.98
441_D445_A0.8040.98
128_A360_V0.8030.98
402_Y423_Q0.8020.98
33_A37_S0.8020.98
445_A449_K0.8020.98
22_G302_F0.8020.98
54_I58_I0.8010.98
58_I259_G0.8010.98
63_G259_G0.7980.98
159_I172_P0.7960.98
194_G319_M0.7960.98
157_V160_Y0.7950.98
66_G290_G0.7930.98
83_V91_L0.7920.98
94_A98_T0.7900.98
235_E239_T0.7890.98
37_S46_V0.7880.98
128_A357_V0.7880.98
75_M231_V0.7880.98
101_I105_L0.7880.98
352_V380_F0.7880.98
72_T279_I0.7870.98
250_D418_N0.7830.98
347_L351_I0.7810.98
388_L415_D0.7800.98
215_F218_L0.7790.98
13_G16_R0.7760.98
468_K471_K0.7760.98
71_A281_Q0.7750.98
42_V88_L0.7750.98
310_L313_V0.7700.97
151_M155_S0.7700.97
452_A455_K0.7680.97
105_L257_S0.7670.97
265_I269_F0.7610.97
48_L307_I0.7600.97
107_I110_I0.7590.97
159_I171_S0.7580.97
404_V416_L0.7580.97
190_V194_G0.7550.97
338_S341_G0.7530.97
193_V196_M0.7530.97
447_L451_V0.7520.97
89_Q92_F0.7520.97
53_C57_I0.7520.97
353_M357_V0.7500.97
454_F461_A0.7400.97
263_A266_V0.7400.97
401_T430_V0.7370.97
262_I265_I0.7360.97
28_A32_E0.7360.97
28_A33_A0.7330.97
151_M154_G0.7330.97
62_G259_G0.7290.96
425_D459_I0.7290.96
45_M307_I0.7270.96
51_S303_L0.7240.96
375_L379_V0.7200.96
469_A472_S0.7200.96
78_V81_S0.7190.96
119_R445_A0.7170.96
66_G249_T0.7160.96
341_G445_A0.7160.96
403_Q432_D0.7160.96
46_V273_M0.7130.96
281_Q326_M0.7110.96
328_M332_G0.7110.96
32_E129_L0.7100.96
266_V272_G0.7100.96
207_L271_G0.7090.96
200_S203_L0.7070.96
49_Y202_S0.7070.96
86_H89_Q0.7070.96
129_L279_I0.7050.96
41_G80_V0.7050.96
446_A450_I0.7050.96
263_A275_G0.7040.96
295_S299_A0.7030.96
180_T317_I0.7030.96
94_A224_Y0.7030.96
97_L100_I0.7030.96
470_S473_L0.7020.96
328_M331_V0.7010.96
74_S129_L0.6990.96
26_A303_L0.6980.96
90_Y93_A0.6930.95
215_F219_Q0.6890.95
91_L274_A0.6870.95
222_F225_S0.6870.95
455_K460_E0.6850.95
75_M79_M0.6830.95
420_F454_F0.6830.95
425_D457_Q0.6820.95
179_M182_I0.6810.95
90_Y217_T0.6800.95
79_M91_L0.6780.95
151_M320_A0.6780.95
283_V287_K0.6770.95
29_L32_E0.6770.95
52_F56_I0.6760.95
466_L471_K0.6740.95
29_L55_A0.6740.95
170_P173_L0.6730.95
400_R423_Q0.6720.95
39_I74_S0.6720.95
98_T232_G0.6690.94
236_S277_A0.6680.94
178_V181_I0.6680.94
175_A321_A0.6670.94
36_F280_G0.6660.94
86_H217_T0.6640.94
59_S63_G0.6640.94
122_M241_Q0.6640.94
207_L210_D0.6630.94
125_F235_E0.6610.94
341_G344_K0.6600.94
151_M182_I0.6590.94
268_G272_G0.6590.94
203_L209_P0.6580.94
12_F15_I0.6550.94
123_I338_S0.6550.94
81_S85_D0.6540.94
147_S151_M0.6530.94
33_A36_F0.6520.94
453_K456_E0.6510.94
162_L166_T0.6510.94
34_I199_I0.6510.94
65_P249_T0.6500.93
342_L350_S0.6490.93
175_A179_M0.6480.93
194_G315_V0.6470.93
352_V376_L0.6470.93
26_A72_T0.6470.93
237_L251_S0.6440.93
240_A251_S0.6440.93
63_G251_S0.6420.93
14_N292_G0.6420.93
448_D452_A0.6420.93
346_P349_D0.6420.93
278_M281_Q0.6410.93
52_F307_I0.6390.93
122_M333_T0.6380.93
151_M193_V0.6360.93
99_G106_G0.6360.93
32_E278_M0.6360.93
55_A299_A0.6350.93
126_V242_I0.6310.92
102_Q229_A0.6290.92
379_V383_A0.6270.92
172_P325_V0.6260.92
106_G254_N0.6230.92
86_H220_I0.6230.92
39_I72_T0.6220.92
72_T235_E0.6220.92
56_I60_I0.6210.92
274_A281_Q0.6200.92
151_M188_V0.6190.92
401_T432_D0.6170.92
15_I292_G0.6170.92
104_I215_F0.6160.92
203_L206_F0.6160.92
417_T446_A0.6140.91
408_I443_G0.6120.91
18_D21_A0.6120.91
391_V405_K0.6120.91
126_V333_T0.6110.91
238_L279_I0.6110.91
28_A326_M0.6100.91
58_I62_G0.6090.91
153_A161_V0.6090.91
239_T277_A0.6080.91
248_D453_K0.6080.91
386_S412_S0.6070.91
282_S290_G0.6070.91
66_G243_I0.6070.91
121_V373_G0.6050.91
221_I225_S0.6050.91
335_D339_L0.6050.91
405_K467_N0.6030.91
416_L431_I0.6010.91
308_A312_H0.6000.90
345_A441_D0.5990.90
14_N17_K0.5980.90
242_I246_M0.5960.90
351_I376_L0.5960.90
132_L330_S0.5960.90
343_K346_P0.5950.90
433_L464_K0.5940.90
347_L350_S0.5940.90
102_Q260_Q0.5930.90
321_A325_V0.5930.90
356_T366_L0.5930.90
455_K458_G0.5910.90
221_I224_Y0.5890.90
425_D429_V0.5890.90
450_I454_F0.5890.90
444_A473_L0.5880.90
155_S158_I0.5880.90
32_E299_A0.5860.89
37_S43_D0.5840.89
426_I429_V0.5840.89
287_K332_G0.5830.89
100_I269_F0.5830.89
187_H191_R0.5820.89
194_G197_G0.5820.89
296_A300_G0.5800.89
158_I179_M0.5780.89
244_D250_D0.5780.89
277_A282_S0.5760.89
398_K426_I0.5760.89
92_F267_T0.5760.89
262_I266_V0.5760.89
103_V261_G0.5730.88
40_A76_A0.5730.88
188_V191_R0.5720.88
308_A314_V0.5720.88
76_A79_M0.5720.88
105_L226_I0.5710.88
129_L238_L0.5710.88
404_V433_L0.5700.88
159_I328_M0.5700.88
278_M326_M0.5680.88
227_A367_S0.5680.88
72_T117_I0.5680.88
116_F386_S0.5670.88
147_S188_V0.5670.88
237_L373_G0.5670.88
278_M282_S0.5650.88
23_I298_V0.5640.88
123_I353_M0.5630.88
58_I63_G0.5630.88
236_S276_C0.5620.87
50_A53_C0.5620.87
181_I186_F0.5620.87
228_L274_A0.5620.87
93_A208_I0.5620.87
105_L230_F0.5610.87
70_A296_A0.5600.87
158_I162_L0.5590.87
202_S307_I0.5590.87
404_V436_A0.5580.87
426_I454_F0.5580.87
239_T283_V0.5570.87
72_T126_V0.5570.87
46_V50_A0.5560.87
58_I61_F0.5560.87
345_A349_D0.5530.87
68_I278_M0.5520.86
32_E39_I0.5500.86
32_E68_I0.5490.86
327_V330_S0.5490.86
245_E445_A0.5480.86
204_P209_P0.5480.86
96_I100_I0.5480.86
74_S235_E0.5480.86
403_Q434_T0.5480.86
64_R244_D0.5470.86
32_E281_Q0.5470.86
205_H271_G0.5470.86
389_K405_K0.5460.86
271_G373_G0.5450.86
178_V182_I0.5450.86
239_T276_C0.5440.86
360_V372_V0.5430.86
87_G90_Y0.5420.85
175_A325_V0.5400.85
363_T372_V0.5400.85
74_S326_M0.5400.85
449_K452_A0.5390.85
350_S353_M0.5370.85
260_Q263_A0.5340.85
49_Y204_P0.5340.85
127_N338_S0.5330.85
281_Q333_T0.5330.85
418_N422_Y0.5310.84
126_V279_I0.5310.84
36_F54_I0.5300.84
302_F306_L0.5290.84
189_D192_T0.5280.84
399_L403_Q0.5280.84
97_L218_L0.5270.84
339_L343_K0.5270.84
76_A133_I0.5260.84
32_E326_M0.5260.84
390_I405_K0.5250.84
85_D207_L0.5250.84
301_A304_M0.5240.84
32_E238_L0.5240.84
413_V443_G0.5230.83
123_I335_D0.5220.83
37_S44_P0.5220.83
417_T453_K0.5220.83
413_V417_T0.5220.83
126_V281_Q0.5220.83
176_I179_M0.5220.83
32_E36_F0.5210.83
118_P433_L0.5210.83
16_R19_I0.5200.83
232_G236_S0.5190.83
386_S390_I0.5180.83
267_T275_G0.5180.83
175_A183_A0.5180.83
72_T129_L0.5180.83
183_A195_D0.5170.83
62_G70_A0.5170.83
223_P438_V0.5170.83
338_S353_M0.5160.83
68_I72_T0.5160.83
150_A425_D0.5150.82
237_L243_I0.5150.82
384_K438_V0.5150.82
63_G77_V0.5140.82
127_N334_F0.5120.82
40_A48_L0.5120.82
27_L128_A0.5120.82
35_G39_I0.5110.82
73_G326_M0.5100.82
61_F255_K0.5100.82
46_V271_G0.5100.82
191_R196_M0.5090.82
131_I366_L0.5090.82
89_Q210_D0.5080.82
280_G283_V0.5080.82
211_V214_T0.5070.82
235_E366_L0.5070.82
152_L323_V0.5070.82
217_T222_F0.5060.81
304_M308_A0.5060.81
78_V82_L0.5060.81
150_A157_V0.5040.81
151_M183_A0.5030.81
108_S375_L0.5030.81
297_F300_G0.5020.81
116_F415_D0.5010.81
34_I326_M0.5010.81
454_F457_Q0.5010.81
178_V458_G0.5000.81
279_I333_T0.5000.81
235_E278_M0.5000.81
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3qe7A 2 0.7699 100 0.612 Contact Map
3ny7A 1 0.2008 99.4 0.87 Contact Map
3oizA 1 0.1904 99.3 0.874 Contact Map
2klnA 1 0.1987 99.3 0.875 Contact Map
3lloA 1 0.2197 99.3 0.877 Contact Map
3zxnA 1 0.1883 99.2 0.88 Contact Map
4hylA 2 0.1946 99.2 0.881 Contact Map
4dghA 4 0.2071 99.2 0.881 Contact Map
4xs5A 1 0.1904 99.2 0.882 Contact Map
2ka5A 1 0.2113 99.2 0.882 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0131 seconds.