YXEI - BACSU - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

YXEI - Uncharacterized protein YxeI

UniProt:	P54948	Sequences: MCTSLTLETADRKHVLARTMDFAFQLGTEVILYPRRYSWNSEADGRAHQTQYAFIGMGRKLGNILFADGINESGLSCAALYFPGYAEYEKTIREDTVHIVPHEFVTWVLSVCQSLEDVKEKIRSLTIVEKKLDLLDTVLPLHWILSDRTGRNLTIEPRADGLKVYDNQPGVMTNSPDFIWHVTNLQQYTGIRPKQLESKEMGGLALSAFGQGLGTVGLPGDYTPPSRFVRAVYLKEHLEPAADETKGVTAAFQILANMTIPKGAVITEEDEIHYTQYTSVMCNETGNYYFHHYDNRQIQKVNLFHEDLDCLEPKVFSAKAEESIHELN	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	328 (290)
Sequences:	1245 (924)
Seq/√Len:	54.3

BACSU - YXEI

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
112_C	121_K	4.134	1.00
77_C	105_V	3.543	1.00
73_S	113_Q	3.430	1.00
145_L	155_I	3.386	1.00
243_D	246_K	3.131	1.00
35_R	72_E	2.974	1.00
221_D	226_S	2.965	1.00
302_N	305_H	2.925	1.00
70_I	76_S	2.901	1.00
282_C	285_T	2.762	1.00
116_E	151_R	2.751	1.00
118_V	145_L	2.684	1.00
158_R	163_K	2.676	1.00
262_K	274_Y	2.601	1.00
148_R	286_G	2.594	1.00
119_K	151_R	2.481	1.00
184_N	187_Q	2.445	1.00
108_V	145_L	2.441	1.00
33_Y	66_F	2.417	1.00
113_Q	117_D	2.410	1.00
151_R	166_D	2.363	1.00
184_N	229_V	2.361	1.00
3_T	231_A	2.334	1.00
165_Y	179_I	2.226	1.00
83_P	224_P	2.225	1.00
252_F	280_V	2.163	1.00
38_S	49_Q	2.148	1.00
52_Y	72_E	2.137	1.00
252_F	298_I	2.135	1.00
84_G	175_S	2.117	1.00
54_F	110_S	2.114	1.00
184_N	188_Y	2.108	1.00
116_E	120_E	2.103	1.00
241_A	246_K	2.072	1.00
119_K	166_D	2.051	1.00
87_E	159_A	2.036	1.00
77_C	145_L	2.019	1.00
163_K	179_I	2.009	1.00
10_A	242_A	1.976	1.00
70_I	281_M	1.972	1.00
28_T	57_M	1.937	1.00
256_A	259_T	1.871	0.99
76_S	283_N	1.871	0.99
19_T	259_T	1.852	0.99
69_G	109_L	1.847	0.99
286_G	304_F	1.839	0.99
4_S	80_L	1.834	0.99
17_A	255_L	1.820	0.99
17_A	251_A	1.802	0.99
217_G	221_D	1.770	0.99
75_L	114_S	1.753	0.99
22_F	140_P	1.720	0.99
180_W	184_N	1.710	0.99
281_M	288_Y	1.708	0.99
108_V	122_I	1.694	0.99
287_N	300_K	1.691	0.99
287_N	302_N	1.684	0.99
168_Q	178_F	1.623	0.98
9_T	247_G	1.588	0.98
120_E	123_R	1.582	0.98
82_F	86_A	1.553	0.98
101_P	127_I	1.540	0.98
38_S	47_A	1.510	0.97
90_K	129_E	1.502	0.97
104_F	155_I	1.494	0.97
291_H	296_R	1.488	0.97
32_L	306_E	1.488	0.97
57_M	288_Y	1.484	0.97
82_F	158_R	1.474	0.97
98_H	126_T	1.469	0.97
19_T	278_T	1.463	0.97
14_H	284_E	1.457	0.97
21_D	259_T	1.433	0.96
167_N	178_F	1.412	0.96
155_I	162_L	1.403	0.96
180_W	187_Q	1.367	0.95
153_L	164_V	1.360	0.95
50_T	110_S	1.355	0.95
238_L	250_A	1.355	0.95
108_V	118_V	1.352	0.95
35_R	308_L	1.341	0.95
52_Y	113_Q	1.340	0.95
115_L	150_G	1.330	0.95
77_C	108_V	1.322	0.94
186_Q	225_P	1.295	0.94
157_P	162_L	1.278	0.93
112_C	145_L	1.275	0.93
160_D	163_K	1.274	0.93
212_G	217_G	1.261	0.93
251_A	280_V	1.254	0.93
216_V	221_D	1.251	0.93
30_V	301_V	1.241	0.92
48_H	110_S	1.239	0.92
185_L	232_V	1.234	0.92
148_R	284_E	1.232	0.92
215_T	223_T	1.229	0.92
146_S	152_N	1.226	0.92
51_Q	111_V	1.222	0.92
115_L	164_V	1.222	0.92
169_P	185_L	1.220	0.92
211_Q	224_P	1.211	0.91
278_T	291_H	1.206	0.91
53_A	308_L	1.204	0.91
29_E	315_V	1.201	0.91
183_T	186_Q	1.195	0.91
184_N	225_P	1.190	0.91
256_A	291_H	1.167	0.90
80_L	172_M	1.166	0.90
244_E	285_T	1.159	0.90
40_N	47_A	1.152	0.89
36_R	50_T	1.138	0.89
169_P	235_K	1.125	0.88
122_I	162_L	1.123	0.88
215_T	221_D	1.115	0.88
188_Y	229_V	1.111	0.87
101_P	138_V	1.101	0.87
107_W	112_C	1.093	0.87
231_A	254_I	1.090	0.86
96_T	126_T	1.089	0.86
15_V	247_G	1.085	0.86
181_H	184_N	1.075	0.86
158_R	165_Y	1.073	0.86
122_I	155_I	1.053	0.84
84_G	186_Q	1.051	0.84
5_L	231_A	1.051	0.84
32_L	35_R	1.046	0.84
9_T	13_K	1.043	0.84
21_D	258_M	1.038	0.84
144_I	172_M	1.033	0.83
173_T	224_P	1.029	0.83
21_D	80_L	1.020	0.82
89_E	157_P	1.019	0.82
100_V	138_V	1.017	0.82
35_R	53_A	1.016	0.82
169_P	182_V	1.015	0.82
244_E	282_C	1.010	0.82
2_C	18_R	1.006	0.82
35_R	307_D	1.000	0.81
170_G	235_K	1.000	0.81
82_F	177_D	0.994	0.81
79_A	141_L	0.994	0.81
255_L	278_T	0.990	0.81
56_G	66_F	0.985	0.80
122_I	303_L	0.981	0.80
52_Y	73_S	0.974	0.79
55_I	301_V	0.974	0.79
86_A	288_Y	0.962	0.79
306_E	314_K	0.960	0.78
238_L	254_I	0.960	0.78
5_L	235_K	0.957	0.78
218_L	229_V	0.953	0.78
39_W	54_F	0.950	0.78
29_E	63_N	0.949	0.78
73_S	286_G	0.949	0.78
212_G	216_V	0.945	0.77
39_W	50_T	0.943	0.77
30_V	57_M	0.940	0.77
78_A	144_I	0.932	0.76
51_Q	117_D	0.930	0.76
253_Q	256_A	0.926	0.76
224_P	241_A	0.925	0.76
80_L	288_Y	0.923	0.76
19_T	260_I	0.918	0.75
99_I	108_V	0.911	0.75
16_L	281_M	0.911	0.75
32_L	55_I	0.907	0.74
127_I	138_V	0.905	0.74
92_I	98_H	0.904	0.74
245_T	285_T	0.903	0.74
233_Y	264_A	0.902	0.74
100_V	103_E	0.895	0.73
6_T	235_K	0.894	0.73
119_K	153_L	0.889	0.73
259_T	278_T	0.888	0.73
32_L	314_K	0.886	0.73
16_L	283_N	0.886	0.73
107_W	125_L	0.884	0.72
187_Q	225_P	0.877	0.72
230_R	261_P	0.875	0.72
46_R	99_I	0.872	0.71
20_M	67_A	0.870	0.71
104_F	127_I	0.867	0.71
217_G	226_S	0.866	0.71
28_T	277_Y	0.864	0.71
248_V	289_Y	0.858	0.70
153_L	165_Y	0.855	0.70
87_E	90_K	0.851	0.70
53_A	72_E	0.849	0.69
81_Y	138_V	0.845	0.69
261_P	264_A	0.844	0.69
22_F	81_Y	0.842	0.69
161_G	305_H	0.842	0.69
121_K	124_S	0.836	0.68
41_S	48_H	0.835	0.68
115_L	153_L	0.832	0.68
129_E	138_V	0.825	0.67
234_L	257_N	0.819	0.67
116_E	149_T	0.819	0.67
260_I	273_H	0.818	0.67
177_D	180_W	0.816	0.66
10_A	246_K	0.815	0.66
139_L	276_Q	0.809	0.66
116_E	159_A	0.803	0.65
212_G	221_D	0.803	0.65
266_I	269_E	0.801	0.65
220_G	263_G	0.799	0.65
292_H	295_N	0.798	0.65
75_L	115_L	0.794	0.64
31_I	58_G	0.793	0.64
21_D	260_I	0.792	0.64
76_S	281_M	0.789	0.64
118_V	153_L	0.789	0.64
131_K	138_V	0.788	0.64
4_S	172_M	0.787	0.63
188_Y	214_G	0.783	0.63
21_D	78_A	0.782	0.63
104_F	107_W	0.777	0.62
83_P	88_Y	0.775	0.62
33_Y	54_F	0.775	0.62
6_T	170_G	0.774	0.62
310_C	314_K	0.767	0.61
51_Q	112_C	0.766	0.61
33_Y	37_Y	0.763	0.61
211_Q	273_H	0.762	0.61
28_T	276_Q	0.760	0.61
158_R	177_D	0.759	0.61
70_I	283_N	0.758	0.61
39_W	110_S	0.757	0.60
234_L	264_A	0.755	0.60
26_L	276_Q	0.754	0.60
220_G	226_S	0.749	0.60
106_T	110_S	0.749	0.60
251_A	255_L	0.749	0.60
244_E	248_V	0.748	0.60
172_M	258_M	0.747	0.59
186_Q	265_V	0.742	0.59
215_T	233_Y	0.741	0.59
168_Q	182_V	0.738	0.59
222_Y	234_L	0.736	0.58
295_N	298_I	0.735	0.58
159_A	309_D	0.734	0.58
231_A	234_L	0.732	0.58
219_P	230_R	0.727	0.57
251_A	254_I	0.725	0.57
187_Q	212_G	0.724	0.57
212_G	273_H	0.722	0.57
75_L	112_C	0.719	0.57
10_A	47_A	0.718	0.56
154_T	178_F	0.717	0.56
112_C	118_V	0.717	0.56
83_P	139_L	0.714	0.56
111_V	121_K	0.714	0.56
97_V	124_S	0.710	0.56
180_W	225_P	0.710	0.56
115_L	151_R	0.709	0.55
175_S	214_G	0.707	0.55
187_Q	216_V	0.706	0.55
53_A	309_D	0.704	0.55
240_P	246_K	0.703	0.55
75_L	118_V	0.702	0.55
35_R	309_D	0.702	0.55
301_V	306_E	0.700	0.55
81_Y	136_D	0.696	0.54
16_L	78_A	0.695	0.54
84_G	224_P	0.693	0.54
57_M	290_F	0.693	0.54
4_S	144_I	0.692	0.54
282_C	287_N	0.686	0.53
67_A	81_Y	0.685	0.53
36_R	49_Q	0.685	0.53
214_G	220_G	0.682	0.53
22_F	101_P	0.681	0.53
75_L	121_K	0.679	0.52
54_F	66_F	0.676	0.52
15_V	277_Y	0.676	0.52
224_P	282_C	0.674	0.52
241_A	247_G	0.673	0.52
214_G	219_P	0.671	0.51
222_Y	265_V	0.666	0.51
54_F	300_K	0.666	0.51
118_V	121_K	0.663	0.51
17_A	42_E	0.663	0.51
54_F	106_T	0.663	0.51
142_H	174_N	0.661	0.50
11_D	244_E	0.658	0.50
242_A	310_C	0.657	0.50
6_T	14_H	0.657	0.50
256_A	296_R	0.656	0.50
107_W	111_V	0.655	0.50
99_I	120_E	0.653	0.50
224_P	285_T	0.652	0.49
13_K	285_T	0.652	0.49
32_L	53_A	0.652	0.49
295_N	299_Q	0.651	0.49
256_A	278_T	0.651	0.49
68_D	288_Y	0.649	0.49
131_K	136_D	0.648	0.49
154_T	169_P	0.646	0.49
50_T	311_L	0.646	0.49
20_M	277_Y	0.644	0.49
30_V	181_H	0.643	0.48
311_L	314_K	0.642	0.48
67_A	141_L	0.640	0.48
73_S	114_S	0.639	0.48
101_P	140_P	0.639	0.48
188_Y	220_G	0.633	0.47
59_R	67_A	0.633	0.47
211_Q	265_V	0.632	0.47
95_D	114_S	0.630	0.47
243_D	247_G	0.629	0.47
9_T	15_V	0.628	0.47
219_P	263_G	0.625	0.47
215_T	218_L	0.624	0.46
41_S	107_W	0.624	0.46
77_C	104_F	0.624	0.46
135_L	138_V	0.623	0.46
49_Q	73_S	0.621	0.46
9_T	243_D	0.618	0.46
104_F	143_W	0.617	0.46
234_L	261_P	0.617	0.46
214_G	229_V	0.616	0.46
14_H	283_N	0.616	0.46
240_P	243_D	0.612	0.45
127_I	158_R	0.611	0.45
178_F	182_V	0.606	0.45
46_R	277_Y	0.606	0.45
115_L	147_D	0.606	0.45
155_I	314_K	0.604	0.44
228_F	232_V	0.604	0.44
90_K	124_S	0.602	0.44
113_Q	230_R	0.600	0.44
52_Y	303_L	0.600	0.44
233_Y	266_I	0.599	0.44
248_V	298_I	0.599	0.44
37_Y	248_V	0.596	0.43
253_Q	259_T	0.594	0.43
117_D	120_E	0.593	0.43
81_Y	140_P	0.590	0.43
188_Y	219_P	0.590	0.43
211_Q	267_T	0.590	0.43
302_N	306_E	0.588	0.43
33_Y	39_W	0.587	0.43
33_Y	58_G	0.586	0.42
242_A	246_K	0.584	0.42
97_V	115_L	0.582	0.42
277_Y	281_M	0.579	0.42
113_Q	240_P	0.576	0.41
117_D	245_T	0.575	0.41
19_T	235_K	0.574	0.41
125_L	236_E	0.574	0.41
83_P	140_P	0.572	0.41
223_T	260_I	0.569	0.41
23_A	276_Q	0.568	0.41
25_Q	28_T	0.568	0.41
46_R	155_I	0.568	0.41
309_D	313_P	0.566	0.40
172_M	254_I	0.566	0.40
140_P	276_Q	0.566	0.40
100_V	127_I	0.564	0.40
185_L	188_Y	0.564	0.40
253_Q	293_Y	0.563	0.40
213_L	216_V	0.563	0.40
185_L	212_G	0.563	0.40
176_P	220_G	0.563	0.40
123_R	164_V	0.560	0.40
215_T	272_I	0.558	0.40
17_A	280_V	0.558	0.40
122_I	247_G	0.557	0.39
312_E	315_V	0.555	0.39
217_G	223_T	0.555	0.39
35_R	73_S	0.554	0.39
89_E	107_W	0.551	0.39
2_C	5_L	0.550	0.39
79_A	139_L	0.550	0.39
35_R	254_I	0.550	0.39
58_G	233_Y	0.550	0.39
17_A	213_L	0.549	0.39
11_D	284_E	0.549	0.39
105_V	175_S	0.548	0.39
127_I	148_R	0.548	0.39
154_T	167_N	0.545	0.38
185_L	229_V	0.544	0.38
215_T	222_Y	0.543	0.38
229_V	312_E	0.543	0.38
215_T	264_A	0.542	0.38
121_K	126_T	0.542	0.38
181_H	229_V	0.542	0.38
96_T	111_V	0.541	0.38
83_P	175_S	0.540	0.38
15_V	251_A	0.539	0.38
57_M	281_M	0.537	0.37
219_P	229_V	0.536	0.37
104_F	157_P	0.535	0.37
229_V	246_K	0.534	0.37
120_E	242_A	0.533	0.37
125_L	230_R	0.533	0.37
53_A	70_I	0.531	0.37
234_L	256_A	0.530	0.37
289_Y	295_N	0.527	0.36
96_T	124_S	0.526	0.36
20_M	128_V	0.526	0.36
65_L	81_Y	0.524	0.36
53_A	310_C	0.522	0.36
182_V	286_G	0.521	0.36
45_G	125_L	0.520	0.36
37_Y	58_G	0.518	0.36
64_I	103_E	0.518	0.36
4_S	16_L	0.517	0.35
76_S	105_V	0.517	0.35
11_D	76_S	0.516	0.35
97_V	126_T	0.516	0.35
48_H	114_S	0.515	0.35
116_E	242_A	0.514	0.35
71_N	147_D	0.514	0.35
80_L	258_M	0.513	0.35
170_G	178_F	0.512	0.35
19_T	255_L	0.512	0.35
4_S	78_A	0.512	0.35
115_L	149_T	0.512	0.35
22_F	273_H	0.511	0.35
49_Q	245_T	0.510	0.35
22_F	77_C	0.510	0.35
10_A	240_P	0.510	0.35
25_Q	67_A	0.509	0.35
231_A	252_F	0.508	0.35
48_H	54_F	0.508	0.35
6_T	146_S	0.506	0.34
107_W	118_V	0.505	0.34
90_K	149_T	0.505	0.34
29_E	164_V	0.505	0.34
215_T	266_I	0.503	0.34
59_R	136_D	0.502	0.34
112_C	117_D	0.501	0.34
181_H	261_P	0.501	0.34
83_P	101_P	0.500	0.34

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2oqcA	3	0.9665	100	0.209	Contact Map
2bjfA	3	0.997	100	0.23	Contact Map
2quyA	4	0.997	100	0.242	Contact Map
2hf0A	4	0.9573	100	0.259	Contact Map
3hbcA	4	0.8902	100	0.317	Contact Map
2x1dA	1	0.7409	100	0.595	Contact Map
3gvzA	1	0.7409	100	0.622	Contact Map
3rmhA	2	0.1585	9	0.973	Contact Map
4rf6A	1	0.3445	5.4	0.975	Contact Map
1vq2A	3	0.1829	4.1	0.977	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0098 seconds.