YFIC - BACSU - GREMLIN Contacts

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YFIC - Uncharacterized ABC transporter ATP-binding protein YfiC

UniProt:	P54719	Sequences: MLKDIRKPFQYPKLPIDKKEGAKKRAKAKDTKGTLRRIWSYLAERKGLLILVMLMVVISAIFGLLGPFVIGKAIDHFIVGKTVSGLIPVLLLLLAIYIIQSLSLWFQNYWMITISQGTVFRMRSELFTHLHELPIPFFDKQRHGELMSRVTNDIENVSSTLNTSVIQILSSVITFVGTIAVMLYMSPLLTLITLTIIPVMAASLKWITNRTGKLFKEQQKNLGDLNGYIEESVSGAKVIKAYSREKQITAEFLEKNAALKTSGFWAQTISGFIPKVMNSLNNLSFTMIAAIGGLFALKGWISIGSIVVFAEYSRQFTRPLNDLANQFNTMLSAIAGAERVFDVLDEKEEREDEKNAVHQPIQTGSIEFRDVSFGYDKGQQTLKHLQFTVPAGQSIAFVGPTGAGKTTVTNLLARFYEPNDGKILIDGTDIKTLTRASLRKNMGFVLQDSFLFQGTIRENIRYGRLDASDQEVEAAAKTANAHSFIERLPKGYDTVLTQNGSGISQGQKQLISIARAVLADPVLLILDEATSNIDTVTEVNIQEALARLMEGRTSVIIAHRLNTIQRADQIVVLKNGEMIEKGSHDELIRQKGFYSDLYESQFEK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	604 (563)
Sequences:	52716 (37233)
Seq/√Len:	1569.2

ECOLI - MSBA CYDD MDLB MDLA CYDC YOJI YDDA
BACSU - YFIC YHEH YKNV SUNT BMRA YGAD YKNU YWJA CYDD YHEI YFIB CYDC YVRA OPUAA OPUCA
HALSA - Q9HSQ7 Q9HMX3 Q9HMW0 BTUDA
SULSO - Q97UJ9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
482_H	492_Y	4.401	1.00
367_E	388_T	4.359	1.00
393_Q	569_Q	4.214	1.00
390_P	393_Q	4.207	1.00
370_D	384_H	4.202	1.00
569_Q	581_K	3.994	1.00
454_G	458_E	3.920	1.00
457_R	469_D	3.810	1.00
369_R	422_K	3.804	1.00
477_K	482_H	3.797	1.00
584_H	594_Y	3.746	1.00
365_S	388_T	3.481	1.00
369_R	424_L	3.473	1.00
482_H	486_E	3.423	1.00
422_K	429_D	3.268	1.00
383_K	577_E	3.096	1.00
457_R	493_D	3.031	1.00
457_R	461_R	2.943	1.00
591_K	595_S	2.900	1.00
469_D	473_E	2.899	1.00
368_F	371_V	2.896	1.00
468_S	471_E	2.875	1.00
380_Q	383_K	2.869	1.00
595_S	599_E	2.843	1.00
476_A	492_Y	2.773	1.00
372_S	384_H	2.727	1.00
409_T	557_I	2.704	1.00
441_N	522_V	2.620	1.00
409_T	525_I	2.609	1.00
580_E	590_Q	2.565	1.00
367_E	424_L	2.550	1.00
474_A	478_T	2.516	1.00
365_S	390_P	2.440	1.00
374_G	380_Q	2.403	1.00
473_E	482_H	2.388	1.00
571_V	581_K	2.363	1.00
583_S	586_E	2.359	1.00
180_A	184_Y	2.331	1.00
460_I	476_A	2.322	1.00
520_D	552_R	2.320	1.00
414_R	417_E	2.310	1.00
389_V	395_I	2.309	1.00
434_T	437_S	2.308	1.00
372_S	380_Q	2.260	1.00
372_S	420_D	2.258	1.00
457_R	472_V	2.247	1.00
464_R	471_E	2.240	1.00
75_D	304_G	2.225	1.00
443_G	521_P	2.221	1.00
580_E	591_K	2.212	1.00
580_E	592_G	2.199	1.00
365_S	391_A	2.115	1.00
394_S	567_A	2.115	1.00
574_K	593_F	2.088	1.00
473_E	477_K	2.085	1.00
490_K	494_T	2.085	1.00
387_F	571_V	2.077	1.00
546_A	566_R	2.016	1.00
37_R	345_D	2.000	1.00
481_A	484_F	1.989	1.00
368_F	387_F	1.981	1.00
75_D	302_S	1.974	1.00
460_I	472_V	1.967	1.00
471_E	520_D	1.942	1.00
538_E	560_R	1.941	1.00
417_E	431_K	1.923	1.00
374_G	419_N	1.911	1.00
389_V	555_V	1.910	1.00
45_R	121_R	1.907	1.00
370_D	386_Q	1.894	1.00
41_Y	125_E	1.894	1.00
473_E	486_E	1.880	1.00
129_H	348_E	1.879	1.00
221_N	258_A	1.873	1.00
582_G	586_E	1.870	1.00
364_G	426_D	1.865	1.00
87_I	91_L	1.860	1.00
43_A	46_K	1.789	1.00
475_A	479_A	1.781	1.00
186_S	295_F	1.770	1.00
341_F	345_D	1.769	1.00
395_I	569_Q	1.762	1.00
469_D	493_D	1.733	1.00
579_I	593_F	1.726	1.00
474_A	477_K	1.721	1.00
461_R	472_V	1.721	1.00
395_I	571_V	1.713	1.00
571_V	578_M	1.694	1.00
408_V	573_L	1.682	1.00
574_K	579_I	1.679	1.00
461_R	469_D	1.668	1.00
480_N	540_N	1.664	1.00
393_Q	568_D	1.659	1.00
396_A	567_A	1.634	1.00
244_R	247_Q	1.633	1.00
394_S	556_I	1.633	1.00
478_T	547_R	1.628	1.00
539_V	543_E	1.619	1.00
533_I	541_I	1.605	1.00
366_I	555_V	1.604	1.00
588_I	598_Y	1.592	1.00
294_L	298_K	1.586	1.00
91_L	95_A	1.583	1.00
429_D	432_T	1.582	1.00
153_D	339_R	1.582	1.00
363_T	426_D	1.580	1.00
496_L	503_I	1.569	1.00
497_T	502_G	1.562	1.00
397_F	571_V	1.546	1.00
460_I	518_L	1.544	1.00
467_A	518_L	1.536	1.00
471_E	474_A	1.526	1.00
365_S	426_D	1.522	1.00
483_S	486_E	1.509	1.00
216_K	338_E	1.505	1.00
476_A	485_I	1.503	1.00
586_E	590_Q	1.503	1.00
132_E	348_E	1.500	1.00
473_E	492_Y	1.493	1.00
580_E	595_S	1.483	1.00
397_F	408_V	1.473	1.00
183_L	190_T	1.467	1.00
565_Q	585_D	1.460	1.00
224_D	258_A	1.448	1.00
71_G	308_V	1.444	1.00
490_K	495_V	1.442	1.00
88_P	92_L	1.437	1.00
390_P	569_Q	1.436	1.00
470_Q	473_E	1.428	1.00
382_L	385_L	1.427	1.00
228_Y	255_K	1.408	1.00
290_A	294_L	1.399	1.00
593_F	596_D	1.391	1.00
558_A	563_T	1.388	1.00
129_H	133_L	1.386	1.00
413_A	444_F	1.385	1.00
543_E	547_R	1.381	1.00
373_F	407_T	1.379	1.00
476_A	482_H	1.379	1.00
400_P	574_K	1.374	1.00
217_E	262_S	1.372	1.00
368_F	412_L	1.371	1.00
585_D	589_R	1.366	1.00
371_V	418_P	1.361	1.00
453_Q	495_V	1.341	1.00
547_R	550_E	1.340	1.00
469_D	472_V	1.337	1.00
384_H	577_E	1.336	1.00
484_F	507_Q	1.335	1.00
183_L	187_P	1.333	1.00
411_L	423_I	1.329	1.00
373_F	411_L	1.307	1.00
362_Q	426_D	1.306	1.00
221_N	224_D	1.292	1.00
221_N	262_S	1.288	1.00
373_F	416_Y	1.285	1.00
443_G	516_A	1.281	1.00
67_P	312_Y	1.280	1.00
396_A	564_I	1.278	1.00
210_R	213_K	1.275	1.00
55_M	103_S	1.263	1.00
471_E	518_L	1.263	1.00
372_S	383_K	1.262	1.00
248_I	462_Y	1.260	1.00
400_P	593_F	1.253	1.00
461_R	467_A	1.250	1.00
364_G	391_A	1.247	1.00
369_R	386_Q	1.239	1.00
488_L	494_T	1.233	1.00
470_Q	474_A	1.229	1.00
202_A	206_W	1.220	1.00
44_E	121_R	1.216	1.00
428_T	432_T	1.214	1.00
478_T	517_V	1.213	1.00
549_M	554_S	1.210	1.00
412_L	555_V	1.209	1.00
401_T	537_T	1.199	1.00
302_S	305_S	1.197	1.00
365_S	427_G	1.197	1.00
295_F	300_W	1.191	1.00
232_S	248_I	1.185	1.00
456_I	511_I	1.183	1.00
64_L	177_G	1.179	1.00
497_T	500_G	1.176	1.00
182_M	309_F	1.172	1.00
84_S	88_P	1.170	1.00
124_S	128_T	1.170	1.00
476_A	481_A	1.168	1.00
391_A	522_V	1.168	1.00
129_H	344_L	1.168	1.00
250_A	254_E	1.167	1.00
387_F	408_V	1.163	1.00
257_A	261_T	1.162	1.00
484_F	488_L	1.161	1.00
395_I	555_V	1.158	1.00
487_R	507_Q	1.158	1.00
481_A	485_I	1.157	1.00
418_P	430_I	1.150	1.00
240_K	245_E	1.146	1.00
189_L	309_F	1.146	1.00
246_K	250_A	1.145	1.00
464_R	467_A	1.142	1.00
385_L	408_V	1.132	1.00
468_S	518_L	1.131	1.00
509_Q	531_S	1.131	1.00
486_E	491_G	1.129	1.00
473_E	476_A	1.127	1.00
570_I	584_H	1.122	1.00
380_Q	419_N	1.115	1.00
141_Q	145_E	1.110	1.00
435_R	439_R	1.109	1.00
363_T	391_A	1.106	1.00
353_E	356_A	1.105	1.00
475_A	517_V	1.104	1.00
139_D	416_Y	1.103	1.00
235_G	450_F	1.101	1.00
503_I	511_I	1.101	1.00
224_D	255_K	1.099	1.00
368_F	423_I	1.093	1.00
128_T	132_E	1.093	1.00
145_E	223_G	1.092	1.00
428_T	433_L	1.092	1.00
58_I	103_S	1.085	1.00
483_S	487_R	1.082	1.00
142_R	145_E	1.078	1.00
389_V	553_T	1.077	1.00
68_F	72_K	1.073	1.00
480_N	537_T	1.072	1.00
214_L	265_W	1.071	1.00
126_L	343_V	1.070	1.00
71_G	75_D	1.067	1.00
196_I	284_S	1.066	1.00
370_D	420_D	1.065	1.00
591_K	599_E	1.064	1.00
48_L	113_T	1.064	1.00
394_S	554_S	1.063	1.00
584_H	588_I	1.054	1.00
129_H	132_E	1.052	1.00
37_R	341_F	1.048	1.00
366_I	412_L	1.046	1.00
368_F	408_V	1.044	1.00
437_S	440_K	1.043	1.00
479_A	514_A	1.041	1.00
254_E	258_A	1.039	1.00
556_I	567_A	1.038	1.00
291_I	295_F	1.037	1.00
113_T	117_G	1.036	1.00
121_R	125_E	1.034	1.00
572_V	593_F	1.033	1.00
292_G	306_I	1.027	1.00
337_A	341_F	1.027	1.00
260_K	264_F	1.026	1.00
188_L	300_W	1.025	1.00
248_I	251_E	1.025	1.00
480_N	543_E	1.023	1.00
425_I	438_L	1.022	1.00
411_L	418_P	1.022	1.00
353_E	432_T	1.020	1.00
449_S	512_S	1.020	1.00
445_V	516_A	1.019	1.00
375_Y	381_T	1.012	1.00
228_Y	251_E	1.011	1.00
69_V	89_V	1.007	1.00
55_M	106_F	1.000	1.00
265_W	268_T	0.999	1.00
558_A	564_I	0.997	1.00
522_V	552_R	0.996	1.00
191_L	195_T	0.995	1.00
71_G	305_S	0.994	1.00
516_A	524_L	0.992	1.00
252_F	256_N	0.990	1.00
380_Q	420_D	0.986	1.00
480_N	544_A	0.986	1.00
247_Q	251_E	0.985	1.00
139_D	410_N	0.983	1.00
474_A	520_D	0.979	1.00
528_E	559_H	0.979	1.00
47_G	51_L	0.977	1.00
206_W	210_R	0.975	1.00
367_E	427_G	0.974	1.00
52_V	111_M	0.973	1.00
480_N	547_R	0.972	1.00
458_E	461_R	0.970	1.00
540_N	543_E	0.970	1.00
176_V	180_A	0.963	1.00
239_I	248_I	0.963	1.00
393_Q	581_K	0.960	1.00
156_N	336_G	0.959	1.00
293_G	297_L	0.956	1.00
475_A	518_L	0.955	1.00
524_L	552_R	0.955	1.00
423_I	430_I	0.951	1.00
185_M	305_S	0.950	1.00
187_P	191_L	0.948	1.00
244_R	248_I	0.948	1.00
536_V	540_N	0.942	1.00
334_I	338_E	0.941	1.00
72_K	76_H	0.940	1.00
396_A	558_A	0.938	1.00
251_E	255_K	0.935	1.00
50_I	54_L	0.933	1.00
88_P	91_L	0.933	1.00
401_T	510_L	0.933	1.00
374_G	378_G	0.932	1.00
120_F	124_S	0.930	1.00
489_P	494_T	0.929	1.00
40_S	43_A	0.929	1.00
217_E	221_N	0.928	1.00
472_V	492_Y	0.928	1.00
210_R	269_I	0.927	1.00
490_K	493_D	0.927	1.00
216_K	220_K	0.926	1.00
414_R	435_R	0.925	1.00
134_P	349_E	0.925	1.00
371_V	411_L	0.923	1.00
55_M	110_W	0.923	1.00
457_R	473_E	0.923	1.00
437_S	441_N	0.921	1.00
403_A	573_L	0.919	1.00
586_E	589_R	0.917	1.00
384_H	420_D	0.916	1.00
478_T	548_L	0.916	1.00
485_I	492_Y	0.915	1.00
258_A	262_S	0.914	1.00
39_W	43_A	0.912	1.00
253_L	257_A	0.912	1.00
203_S	276_V	0.912	1.00
573_L	578_M	0.911	1.00
137_F	141_Q	0.908	1.00
369_R	388_T	0.907	1.00
46_K	50_I	0.907	1.00
477_K	486_E	0.904	1.00
467_A	471_E	0.902	1.00
505_Q	510_L	0.898	1.00
496_L	502_G	0.897	1.00
367_E	386_Q	0.895	1.00
406_T	410_N	0.893	1.00
136_P	349_E	0.893	1.00
126_L	150_V	0.892	1.00
257_A	260_K	0.892	1.00
95_A	99_I	0.890	1.00
457_R	492_Y	0.890	1.00
422_K	431_K	0.889	1.00
247_Q	250_A	0.888	1.00
374_G	381_T	0.887	1.00
394_S	546_A	0.885	1.00
433_L	438_L	0.884	1.00
217_E	265_W	0.881	1.00
192_I	291_I	0.879	1.00
472_V	518_L	0.879	1.00
39_W	42_L	0.875	1.00
214_L	262_S	0.874	1.00
560_R	563_T	0.872	1.00
425_I	523_L	0.871	1.00
153_D	336_G	0.870	1.00
413_A	525_I	0.869	1.00
45_R	117_G	0.869	1.00
436_A	440_K	0.867	1.00
125_E	129_H	0.864	1.00
578_M	581_K	0.864	1.00
218_Q	263_G	0.862	1.00
249_T	253_L	0.859	1.00
394_S	549_M	0.857	1.00
413_A	442_M	0.856	1.00
445_V	513_I	0.856	1.00
295_F	298_K	0.855	1.00
359_Q	433_L	0.854	1.00
391_A	426_D	0.851	1.00
350_R	417_E	0.851	1.00
250_A	253_L	0.850	1.00
596_D	599_E	0.850	1.00
361_I	426_D	0.849	1.00
418_P	423_I	0.848	1.00
418_P	431_K	0.847	1.00
481_A	487_R	0.846	1.00
530_T	541_I	0.845	1.00
149_R	342_D	0.844	1.00
366_I	425_I	0.844	1.00
182_M	190_T	0.843	1.00
255_K	258_A	0.841	1.00
396_A	570_I	0.840	1.00
251_E	254_E	0.839	1.00
524_L	549_M	0.838	1.00
486_E	492_Y	0.838	1.00
296_A	301_I	0.835	1.00
592_G	595_S	0.835	1.00
179_I	190_T	0.835	1.00
237_K	410_N	0.833	1.00
496_L	500_G	0.832	1.00
188_L	295_F	0.831	1.00
513_I	526_L	0.831	1.00
85_G	88_P	0.831	1.00
451_L	511_I	0.831	1.00
478_T	482_H	0.829	1.00
62_F	103_S	0.828	1.00
52_V	114_I	0.827	1.00
68_F	181_V	0.826	1.00
430_I	438_L	0.826	1.00
201_A	205_K	0.826	1.00
210_R	214_L	0.825	1.00
357_V	428_T	0.824	1.00
62_F	99_I	0.823	1.00
357_V	432_T	0.822	1.00
213_K	217_E	0.821	1.00
374_G	377_K	0.819	1.00
136_P	140_K	0.819	1.00
424_L	427_G	0.818	1.00
497_T	501_S	0.818	1.00
591_K	596_D	0.817	1.00
574_K	577_E	0.816	1.00
184_Y	187_P	0.815	1.00
521_P	552_R	0.814	1.00
246_K	249_T	0.812	1.00
479_A	510_L	0.811	1.00
72_K	89_V	0.810	1.00
205_K	209_N	0.809	1.00
36_R	40_S	0.806	1.00
262_S	265_W	0.803	1.00
452_F	459_N	0.800	1.00
385_L	578_M	0.796	1.00
69_V	96_I	0.796	1.00
460_I	511_I	0.794	1.00
451_L	508_K	0.791	1.00
133_L	346_E	0.790	1.00
181_V	185_M	0.788	1.00
440_K	519_A	0.783	1.00
238_V	242_Y	0.782	1.00
102_L	106_F	0.780	1.00
72_K	75_D	0.779	1.00
69_V	92_L	0.778	1.00
455_T	458_E	0.777	1.00
372_S	419_N	0.775	1.00
359_Q	437_S	0.774	1.00
460_I	492_Y	0.772	1.00
225_L	259_L	0.770	1.00
264_F	268_T	0.770	1.00
442_M	523_L	0.770	1.00
56_V	170_S	0.767	1.00
160_T	333_A	0.767	1.00
62_F	96_I	0.767	1.00
296_A	306_I	0.766	1.00
524_L	554_S	0.764	1.00
433_L	437_S	0.763	1.00
448_D	508_K	0.763	1.00
538_E	542_Q	0.763	1.00
181_V	184_Y	0.762	1.00
68_F	71_G	0.760	1.00
461_R	466_D	0.759	1.00
481_A	511_I	0.757	1.00
236_A	240_K	0.757	1.00
145_E	149_R	0.756	1.00
347_K	351_E	0.756	1.00
129_H	347_K	0.755	1.00
376_D	379_Q	0.755	1.00
488_L	503_I	0.754	1.00
258_A	261_T	0.754	1.00
188_L	191_L	0.753	1.00
221_N	255_K	0.752	1.00
61_I	65_L	0.751	1.00
484_F	487_R	0.750	1.00
364_G	553_T	0.750	1.00
261_T	265_W	0.748	1.00
359_Q	362_Q	0.748	1.00
279_S	283_L	0.748	1.00
48_L	110_W	0.746	1.00
461_R	465_L	0.745	1.00
48_L	117_G	0.745	1.00
177_G	180_A	0.744	1.00
588_I	595_S	0.743	1.00
355_N	359_Q	0.741	1.00
195_T	198_P	0.740	1.00
361_I	522_V	0.740	1.00
126_L	340_V	0.740	1.00
340_V	344_L	0.739	1.00
130_L	138_F	0.738	1.00
464_R	520_D	0.737	1.00
156_N	332_S	0.735	1.00
186_S	301_I	0.735	1.00
358_H	437_S	0.732	1.00
542_Q	563_T	0.732	1.00
510_L	537_T	0.730	1.00
105_W	109_Y	0.730	1.00
235_G	238_V	0.727	1.00
476_A	479_A	0.727	1.00
398_V	572_V	0.727	1.00
217_E	220_K	0.726	1.00
90_L	94_L	0.726	1.00
171_S	322_D	0.724	1.00
383_K	575_N	0.724	1.00
186_S	190_T	0.724	1.00
172_V	176_V	0.724	1.00
76_H	85_G	0.723	1.00
190_T	309_F	0.723	1.00
542_Q	558_A	0.723	1.00
60_A	173_I	0.720	1.00
366_I	523_L	0.719	1.00
358_H	434_T	0.719	1.00
480_N	483_S	0.719	1.00
461_R	464_R	0.719	1.00
91_L	94_L	0.719	1.00
125_E	128_T	0.719	1.00
304_G	308_V	0.718	1.00
36_R	39_W	0.717	1.00
75_D	78_I	0.716	1.00
146_L	343_V	0.714	1.00
209_N	213_K	0.714	1.00
134_P	350_R	0.714	1.00
185_M	308_V	0.712	1.00
338_E	342_D	0.711	1.00
92_L	95_A	0.710	1.00
89_V	92_L	0.710	1.00
74_I	307_V	0.708	1.00
183_L	194_L	0.707	1.00
464_R	519_A	0.707	1.00
584_H	598_Y	0.705	1.00
160_T	330_M	0.705	1.00
505_Q	532_N	0.704	1.00
178_T	315_Q	0.703	1.00
509_Q	532_N	0.700	1.00
99_I	103_S	0.700	1.00
590_Q	593_F	0.699	1.00
424_L	429_D	0.698	1.00
401_T	528_E	0.697	1.00
453_Q	497_T	0.694	1.00
295_F	299_G	0.693	1.00
76_H	79_V	0.692	1.00
438_L	442_M	0.692	1.00
392_G	551_G	0.691	1.00
418_P	422_K	0.690	1.00
178_T	316_F	0.689	1.00
128_T	249_T	0.688	1.00
394_S	566_R	0.688	1.00
47_G	50_I	0.688	1.00
51_L	110_W	0.687	1.00
392_G	553_T	0.686	1.00
569_Q	583_S	0.685	1.00
375_Y	407_T	0.684	1.00
478_T	544_A	0.684	1.00
395_I	581_K	0.684	1.00
58_I	99_I	0.682	1.00
456_I	485_I	0.681	1.00
40_S	125_E	0.681	1.00
593_F	597_L	0.680	1.00
410_N	416_Y	0.679	1.00
530_T	538_E	0.677	1.00
585_D	588_I	0.675	1.00
180_A	183_L	0.675	1.00
356_A	359_Q	0.673	1.00
54_L	58_I	0.672	1.00
541_I	544_A	0.672	1.00
333_A	336_G	0.671	1.00
411_L	416_Y	0.671	1.00
580_E	593_F	0.670	1.00
83_V	87_I	0.669	1.00
68_F	185_M	0.668	1.00
471_E	475_A	0.667	1.00
149_R	153_D	0.666	1.00
119_V	158_S	0.666	1.00
580_E	587_L	0.665	1.00
569_Q	586_E	0.665	1.00
356_A	437_S	0.664	1.00
267_Q	271_G	0.663	1.00
133_L	348_E	0.662	1.00
168_I	172_V	0.661	1.00
513_I	517_V	0.657	1.00
409_T	555_V	0.655	1.00
85_G	89_V	0.655	1.00
186_S	189_L	0.654	1.00
37_R	40_S	0.654	1.00
189_L	295_F	0.653	1.00
126_L	344_L	0.652	1.00
214_L	217_E	0.651	1.00
56_V	107_Q	0.650	1.00
454_G	495_V	0.650	1.00
362_Q	441_N	0.649	1.00
382_L	573_L	0.648	1.00
135_I	139_D	0.648	1.00
125_E	344_L	0.647	1.00
481_A	492_Y	0.647	1.00
153_D	219_Q	0.647	1.00
45_R	48_L	0.647	1.00
142_R	227_G	0.646	1.00
202_A	205_K	0.646	1.00
219_Q	222_L	0.646	1.00
350_R	414_R	0.645	1.00
469_D	492_Y	0.643	1.00
157_V	337_A	0.643	1.00
473_E	485_I	0.642	1.00
377_K	419_N	0.642	1.00
59_S	104_L	0.641	1.00
538_E	563_T	0.641	1.00
318_R	322_D	0.640	1.00
544_A	547_R	0.639	1.00
389_V	393_Q	0.639	1.00
564_I	567_A	0.637	1.00
357_V	360_P	0.637	1.00
292_G	296_A	0.636	1.00
87_I	90_L	0.635	1.00
513_I	541_I	0.634	1.00
119_V	123_R	0.634	1.00
193_T	313_S	0.633	1.00
117_G	120_F	0.633	1.00
122_M	154_I	0.631	1.00
129_H	346_E	0.630	1.00
363_T	553_T	0.628	1.00
425_I	430_I	0.626	1.00
580_E	588_I	0.626	1.00
538_E	562_N	0.626	1.00
475_A	514_A	0.626	1.00
523_L	553_T	0.624	1.00
418_P	429_D	0.624	1.00
126_L	154_I	0.623	1.00
397_F	555_V	0.623	1.00
84_S	87_I	0.622	1.00
533_I	537_T	0.621	1.00
75_D	79_V	0.621	1.00
525_I	555_V	0.620	1.00
148_S	226_N	0.616	1.00
265_W	269_I	0.616	1.00
356_A	434_T	0.616	1.00
535_T	538_E	0.613	1.00
504_S	507_Q	0.613	1.00
188_L	291_I	0.613	1.00
368_F	385_L	0.613	1.00
385_L	573_L	0.611	1.00
469_D	476_A	0.611	1.00
220_K	224_D	0.610	1.00
134_P	137_F	0.610	1.00
455_T	493_D	0.608	1.00
580_E	596_D	0.608	1.00
159_S	329_T	0.607	1.00
445_V	526_L	0.607	1.00
491_G	494_T	0.606	1.00
426_D	522_V	0.605	1.00
534_D	537_T	0.604	1.00
98_I	102_L	0.604	1.00
223_G	339_R	0.604	1.00
453_Q	502_G	0.604	1.00
443_G	519_A	0.602	1.00
219_Q	335_A	0.602	1.00
178_T	312_Y	0.602	1.00
374_G	379_Q	0.602	1.00
584_H	587_L	0.601	1.00
120_F	256_N	0.600	1.00
590_Q	595_S	0.600	1.00
581_K	586_E	0.599	1.00
283_L	287_M	0.598	1.00
448_D	499_N	0.598	1.00
215_F	266_A	0.597	1.00
221_N	259_L	0.597	1.00
378_G	381_T	0.597	1.00
148_S	222_L	0.596	1.00
112_I	163_T	0.596	1.00
409_T	444_F	0.596	1.00
65_L	96_I	0.595	1.00
291_I	294_L	0.594	1.00
565_Q	584_H	0.593	1.00
301_I	305_S	0.593	1.00
64_L	67_P	0.591	1.00
206_W	209_N	0.591	1.00
122_M	157_V	0.591	1.00
261_T	264_F	0.591	1.00
207_I	273_I	0.590	1.00
387_F	578_M	0.590	1.00
112_I	116_Q	0.589	1.00
371_V	421_G	0.589	1.00
480_N	541_I	0.589	1.00
155_E	158_S	0.588	1.00
170_S	174_T	0.587	1.00
374_G	420_D	0.586	1.00
145_E	339_R	0.584	1.00
579_I	591_K	0.584	1.00
461_R	476_A	0.584	1.00
351_E	434_T	0.584	1.00
451_L	496_L	0.584	1.00
570_I	583_S	0.584	1.00
278_N	321_N	0.583	1.00
201_A	204_L	0.581	1.00
464_R	518_L	0.581	1.00
479_A	513_I	0.579	1.00
217_E	258_A	0.579	1.00
43_A	47_G	0.578	1.00
474_A	548_L	0.578	1.00
479_A	517_V	0.577	1.00
71_G	304_G	0.577	1.00
45_R	118_T	0.577	1.00
159_S	163_T	0.577	1.00
372_S	382_L	0.576	1.00
140_K	376_D	0.576	1.00
59_S	103_S	0.576	1.00
373_F	381_T	0.576	1.00
510_L	533_I	0.575	1.00
198_P	202_A	0.575	1.00
472_V	476_A	0.574	1.00
371_V	423_I	0.574	1.00
109_Y	113_T	0.573	1.00
389_V	394_S	0.572	1.00
271_G	275_K	0.571	1.00
78_I	81_K	0.570	1.00
45_R	114_I	0.570	1.00
50_I	53_M	0.570	1.00
594_Y	597_L	0.570	1.00
371_V	386_Q	0.569	1.00
575_N	579_I	0.566	1.00
137_F	146_L	0.566	1.00
477_K	483_S	0.566	1.00
214_L	266_A	0.565	1.00
101_S	105_W	0.565	1.00
461_R	518_L	0.565	1.00
82_T	85_G	0.565	1.00
542_Q	556_I	0.565	1.00
238_V	241_A	0.565	1.00
446_L	449_S	0.564	1.00
228_Y	232_S	0.564	1.00
385_L	571_V	0.564	1.00
390_P	395_I	0.563	1.00
353_E	357_V	0.563	1.00
294_L	297_L	0.563	1.00
175_F	179_I	0.562	1.00
167_Q	322_D	0.561	1.00
447_Q	505_Q	0.560	1.00
397_F	557_I	0.560	1.00
116_Q	119_V	0.559	1.00
171_S	175_F	0.558	1.00
398_V	564_I	0.557	1.00
60_A	63_G	0.556	1.00
459_N	511_I	0.556	1.00
435_R	438_L	0.555	1.00
63_G	100_Q	0.555	1.00
68_F	308_V	0.554	1.00
115_S	162_N	0.554	1.00
401_T	558_A	0.554	1.00
228_Y	248_I	0.554	1.00
44_E	125_E	0.553	1.00
127_F	131_H	0.553	1.00
154_I	340_V	0.552	1.00
203_S	280_L	0.552	1.00
48_L	114_I	0.552	1.00
357_V	361_I	0.550	1.00
364_G	522_V	0.550	1.00
143_H	147_M	0.549	1.00
406_T	409_T	0.549	1.00
410_N	444_F	0.548	1.00
572_V	580_E	0.548	1.00
517_V	548_L	0.548	1.00
184_Y	188_L	0.547	1.00
148_S	223_G	0.547	1.00
388_T	581_K	0.547	1.00
588_I	599_E	0.545	1.00
380_Q	384_H	0.545	1.00
485_I	488_L	0.544	1.00
293_G	296_A	0.543	1.00
69_V	72_K	0.543	1.00
187_P	190_T	0.543	1.00
543_E	546_A	0.543	1.00
218_Q	266_A	0.543	1.00
148_S	152_N	0.542	1.00
60_A	64_L	0.542	1.00
292_G	295_F	0.541	1.00
135_I	415_F	0.541	1.00
383_K	386_Q	0.541	1.00
425_I	433_L	0.541	1.00
92_L	96_I	0.541	1.00
526_L	529_A	0.541	1.00
106_F	110_W	0.540	1.00
199_V	202_A	0.539	1.00
506_G	534_D	0.539	1.00
282_N	286_T	0.537	1.00
259_L	263_G	0.537	1.00
482_H	485_I	0.536	1.00
336_G	339_R	0.536	1.00
254_E	257_A	0.535	1.00
530_T	533_I	0.535	1.00
362_Q	391_A	0.535	1.00
477_K	492_Y	0.535	1.00
58_I	62_F	0.533	1.00
355_N	434_T	0.532	1.00
297_L	300_W	0.532	1.00
434_T	438_L	0.532	1.00
301_I	306_I	0.531	1.00
379_Q	383_K	0.530	1.00
476_A	514_A	0.530	1.00
517_V	544_A	0.530	1.00
397_F	573_L	0.529	1.00
182_M	193_T	0.529	1.00
588_I	591_K	0.529	1.00
224_D	227_G	0.528	1.00
549_M	552_R	0.528	1.00
456_I	496_L	0.528	1.00
347_K	350_R	0.527	1.00
94_L	98_I	0.527	1.00
354_K	358_H	0.527	1.00
230_E	234_S	0.527	1.00
131_H	134_P	0.526	1.00
537_T	541_I	0.524	1.00
401_T	533_I	0.524	1.00
529_A	556_I	0.524	1.00
222_L	226_N	0.523	1.00
581_K	590_Q	0.522	1.00
537_T	540_N	0.522	1.00
407_T	416_Y	0.521	1.00
390_P	553_T	0.520	1.00
377_K	380_Q	0.520	1.00
144_G	227_G	0.519	1.00
472_V	475_A	0.517	1.00
355_N	432_T	0.517	1.00
288_I	313_S	0.517	1.00
368_F	411_L	0.515	1.00
42_L	46_K	0.515	1.00
350_R	435_R	0.515	1.00
464_R	468_S	0.515	1.00
355_N	437_S	0.514	1.00
193_T	316_F	0.514	1.00
362_Q	365_S	0.513	1.00
109_Y	112_I	0.513	1.00
79_V	82_T	0.513	1.00
460_I	463_G	0.512	1.00
542_Q	566_R	0.512	1.00
171_S	174_T	0.512	1.00
212_G	338_E	0.512	1.00
119_V	154_I	0.511	1.00
59_S	63_G	0.511	1.00
77_F	85_G	0.510	1.00
445_V	529_A	0.510	1.00
149_R	339_R	0.510	1.00
362_Q	425_I	0.509	1.00
574_K	596_D	0.508	1.00
138_F	141_Q	0.508	1.00
556_I	564_I	0.508	1.00
150_V	154_I	0.508	1.00
523_L	555_V	0.507	1.00
389_V	571_V	0.506	1.00
199_V	203_S	0.506	1.00
354_K	357_V	0.505	1.00
239_I	245_E	0.505	1.00
555_V	571_V	0.504	1.00
69_V	93_L	0.504	1.00
428_T	437_S	0.504	1.00
388_T	391_A	0.504	1.00
214_L	269_I	0.503	1.00
218_Q	222_L	0.502	1.00
68_F	312_Y	0.501	1.00
287_M	291_I	0.500	1.00
456_I	481_A	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4ry2A	2	0.9768	100	0.092	Contact Map
4a82A	2	0.9437	100	0.124	Contact Map
4q4hB	1	0.9652	100	0.155	Contact Map
4f4cA	1	0.9487	100	0.162	Contact Map
3b5xA	2	0.9437	100	0.169	Contact Map
3b60A	2	0.9437	100	0.169	Contact Map
4q9hA	1	0.9487	100	0.171	Contact Map
4q4hA	1	0.9454	100	0.172	Contact Map
4mrsA	2	0.9636	100	0.175	Contact Map
3zdqA	2	0.9272	100	0.177	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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