YFIB - BACSU - GREMLIN Contacts

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YFIB - Uncharacterized ABC transporter ATP-binding protein YfiB

UniProt:	P54718	Sequences: MQKALSFLKPYSLLAGIALILMLTELAVELMQPLLIAKIIDDGILKQDLRHVWIWGTVMIGLTVLSFAAGMLNSFYAAHVSQSFSYDTRKGLFQKIQSFSYSTFGQFSSSSYITRLTNDVTQVQNMIFMSLRFMLRAPLMIAGGIVLSLAVNVKLGFFLLVTIPILILFLLWVLRKGGALFRSVQKRLDQVNTIMQENLIAIKLIKALLRGSHEVKRFIKANTRLMEKTVSAFQLVEFTMPVLMLLMNLCILLILWAGSYSITSGSTQVGDVVAIINYATRITGALSMFPFLIMIFTRAKASGDRIGEVLETEGDEREEGTISDRLSGRIEFQHVSFRYPEMDREALRNVSFSAKPRETIAILGATGSGKSTLFQLIPRLYQPDSGRIYIDEKPVQDIPAEGLRRQIGYVPQEVLLFSGTIKENIAWGKENASLDEIMDAAKLAQIHETILKLPNGYDTVLGQRGVNLSGGQKQRISIARALIRKPAILLLDDSTSALDLQTEAKLLEAISTYHCTTLIITQKITTAMKADQILLLEDGELIEKGTHSELLSESQLYKRIYESQFGREGSESC	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	573 (554)
Sequences:	52300 (37096)
Seq/√Len:	1576.0

ECOLI - MSBA MDLA MDLB CYDD CYDC YOJI YDDA PROV POTG ARAG CYSA POTA MACB RBSA
BACSU - YFIB YHEH YGAD SUNT YWJA YFIC YHEI BMRA YKNU YKNV CYDD CYDC YVRA OPUAA OPUCA OPUBA TAGH MSMX
HALSA - Q9HSQ7 Q9HMX3 BTUDA Q9HMW0 Q9HHQ5
SULSO - Q97UJ9 Q97VF5 Q97UF2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
447_H	457_Y	4.579	1.00
358_E	532_Q	4.479	1.00
334_H	349_N	4.440	1.00
355_K	358_E	4.288	1.00
331_E	353_S	4.252	1.00
419_G	423_E	3.967	1.00
333_Q	387_R	3.930	1.00
532_Q	544_K	3.814	1.00
547_H	557_Y	3.713	1.00
422_K	434_L	3.697	1.00
442_K	447_H	3.608	1.00
387_R	394_P	3.374	1.00
447_H	451_L	3.326	1.00
333_Q	389_Y	3.325	1.00
329_R	353_S	3.231	1.00
332_F	335_V	3.147	1.00
348_R	540_E	3.068	1.00
554_S	558_K	3.014	1.00
422_K	458_D	2.966	1.00
422_K	426_A	2.955	1.00
433_S	436_E	2.944	1.00
374_F	520_I	2.923	1.00
441_A	457_Y	2.909	1.00
374_F	490_L	2.783	1.00
336_S	349_N	2.772	1.00
434_L	438_M	2.736	1.00
345_E	348_R	2.637	1.00
406_Q	487_A	2.568	1.00
425_I	441_A	2.552	1.00
439_D	443_L	2.468	1.00
331_E	389_Y	2.453	1.00
354_A	360_I	2.437	1.00
408_G	486_P	2.432	1.00
485_K	515_C	2.387	1.00
379_R	382_Q	2.387	1.00
329_R	355_K	2.382	1.00
543_E	553_E	2.365	1.00
41_D	270_G	2.360	1.00
438_M	447_H	2.346	1.00
429_K	436_E	2.321	1.00
146_V	150_A	2.305	1.00
455_N	459_T	2.290	1.00
534_L	544_K	2.257	1.00
338_R	345_E	2.255	1.00
352_F	534_L	2.245	1.00
543_E	555_Q	2.231	1.00
399_P	402_G	2.223	1.00
546_T	549_E	2.215	1.00
359_T	530_A	2.202	1.00
422_K	437_I	2.180	1.00
446_I	449_T	2.164	1.00
41_D	268_Q	2.152	1.00
438_M	442_K	2.142	1.00
336_S	345_E	2.141	1.00
332_F	352_F	2.128	1.00
329_R	356_P	2.118	1.00
543_E	554_S	2.117	1.00
425_I	437_I	2.099	1.00
7_F	91_G	2.090	1.00
336_S	385_S	2.074	1.00
328_G	391_D	2.007	1.00
382_Q	396_Q	1.948	1.00
354_A	518_L	1.946	1.00
511_S	529_K	1.935	1.00
503_E	523_K	1.927	1.00
334_H	351_S	1.914	1.00
307_G	311_E	1.880	1.00
436_E	485_K	1.879	1.00
338_R	384_D	1.879	1.00
11_Y	87_D	1.876	1.00
360_I	532_Q	1.847	1.00
152_N	261_S	1.847	1.00
9_K	12_S	1.840	1.00
438_M	451_L	1.833	1.00
545_G	549_E	1.812	1.00
537_E	556_L	1.805	1.00
440_A	444_A	1.802	1.00
426_A	437_I	1.796	1.00
439_D	442_K	1.782	1.00
187_R	224_R	1.755	1.00
53_W	57_T	1.750	1.00
426_A	434_L	1.736	1.00
360_I	534_L	1.722	1.00
498_L	506_L	1.700	1.00
373_L	536_L	1.686	1.00
504_A	508_E	1.680	1.00
318_E	399_P	1.677	1.00
534_L	541_L	1.674	1.00
361_A	530_A	1.670	1.00
119_D	305_R	1.662	1.00
330_I	518_L	1.656	1.00
543_E	558_K	1.625	1.00
441_A	450_I	1.624	1.00
425_I	483_I	1.621	1.00
327_S	391_D	1.618	1.00
557_Y	560_I	1.616	1.00
57_T	61_G	1.614	1.00
556_L	560_I	1.613	1.00
434_L	458_D	1.605	1.00
394_P	397_D	1.602	1.00
462_G	467_N	1.601	1.00
347_L	350_V	1.588	1.00
182_R	304_D	1.587	1.00
210_R	213_H	1.580	1.00
445_Q	505_K	1.569	1.00
358_E	531_D	1.564	1.00
443_L	512_T	1.563	1.00
461_L	468_L	1.563	1.00
537_E	542_I	1.554	1.00
359_T	519_I	1.552	1.00
362_I	373_L	1.552	1.00
329_R	391_D	1.545	1.00
438_M	457_Y	1.530	1.00
521_T	526_T	1.519	1.00
448_E	451_L	1.517	1.00
340_P	343_D	1.505	1.00
528_M	548_S	1.499	1.00
362_I	534_L	1.499	1.00
551_L	561_Y	1.472	1.00
542_I	556_L	1.466	1.00
149_L	156_G	1.459	1.00
95_K	99_F	1.456	1.00
95_K	314_G	1.454	1.00
260_Y	264_S	1.454	1.00
441_A	447_H	1.444	1.00
37_A	274_A	1.442	1.00
355_K	532_Q	1.440	1.00
337_F	372_T	1.436	1.00
432_A	483_I	1.427	1.00
436_E	439_D	1.426	1.00
435_D	438_M	1.422	1.00
549_E	553_E	1.409	1.00
376_L	388_I	1.409	1.00
190_Q	224_R	1.404	1.00
33_P	278_Y	1.399	1.00
378_P	409_Y	1.386	1.00
349_N	540_E	1.384	1.00
256_W	260_Y	1.380	1.00
54_I	58_V	1.367	1.00
455_N	460_V	1.355	1.00
434_L	437_I	1.351	1.00
462_G	465_G	1.340	1.00
214_E	427_W	1.340	1.00
365_A	537_E	1.336	1.00
449_T	472_Q	1.325	1.00
556_L	559_R	1.321	1.00
194_I	221_A	1.321	1.00
408_G	481_A	1.320	1.00
337_F	376_L	1.315	1.00
337_F	381_Y	1.311	1.00
508_E	512_T	1.308	1.00
421_I	476_I	1.305	1.00
436_E	483_I	1.300	1.00
332_F	377_I	1.299	1.00
548_S	552_S	1.298	1.00
361_A	527_A	1.298	1.00
426_A	432_A	1.294	1.00
328_G	356_P	1.293	1.00
95_K	310_L	1.292	1.00
335_V	383_P	1.286	1.00
326_L	391_D	1.283	1.00
149_L	153_V	1.281	1.00
418_S	460_V	1.257	1.00
365_A	556_L	1.255	1.00
21_L	69_A	1.250	1.00
333_Q	351_S	1.249	1.00
366_T	502_T	1.242	1.00
155_L	275_I	1.241	1.00
383_P	395_V	1.240	1.00
441_A	446_I	1.238	1.00
453_L	459_T	1.236	1.00
148_S	275_I	1.226	1.00
176_K	179_A	1.215	1.00
183_S	228_K	1.210	1.00
429_K	432_A	1.200	1.00
187_R	228_K	1.195	1.00
440_A	482_L	1.190	1.00
446_I	450_I	1.183	1.00
360_I	518_L	1.182	1.00
30_L	143_G	1.180	1.00
452_K	472_Q	1.178	1.00
533_I	547_H	1.177	1.00
206_K	211_G	1.176	1.00
377_I	518_L	1.176	1.00
329_R	392_E	1.176	1.00
98_S	314_G	1.173	1.00
449_T	453_L	1.171	1.00
443_L	482_L	1.171	1.00
393_K	397_D	1.170	1.00
168_L	172_W	1.159	1.00
187_R	190_Q	1.158	1.00
201_A	415_L	1.154	1.00
400_A	404_R	1.152	1.00
435_D	439_D	1.152	1.00
433_S	483_I	1.151	1.00
356_P	487_A	1.150	1.00
474_Q	496_S	1.146	1.00
198_N	214_E	1.144	1.00
336_S	348_R	1.143	1.00
438_M	441_A	1.141	1.00
350_V	373_L	1.139	1.00
105_G	381_Y	1.133	1.00
468_L	476_I	1.130	1.00
10_P	87_D	1.125	1.00
92_L	309_V	1.124	1.00
352_F	373_L	1.121	1.00
216_K	220_K	1.120	1.00
445_Q	502_T	1.119	1.00
318_E	400_A	1.119	1.00
212_S	216_K	1.118	1.00
268_Q	271_D	1.115	1.00
24_T	69_A	1.110	1.00
354_A	516_T	1.102	1.00
521_T	527_A	1.102	1.00
393_K	398_I	1.098	1.00
257_A	261_S	1.094	1.00
37_A	41_D	1.082	1.00
223_T	227_E	1.081	1.00
334_H	385_S	1.080	1.00
90_K	94_Q	1.076	1.00
359_T	517_T	1.076	1.00
410_V	481_A	1.074	1.00
50_R	54_I	1.072	1.00
557_Y	561_Y	1.065	1.00
332_F	388_I	1.065	1.00
470_G	475_R	1.064	1.00
481_A	489_L	1.063	1.00
261_S	266_S	1.062	1.00
107_F	111_S	1.062	1.00
547_H	551_L	1.060	1.00
111_S	189_D	1.058	1.00
327_S	356_P	1.057	1.00
345_E	384_D	1.051	1.00
108_S	111_S	1.050	1.00
451_L	456_G	1.049	1.00
303_G	307_G	1.043	1.00
444_A	479_A	1.042	1.00
493_D	522_Q	1.040	1.00
105_G	375_Q	1.040	1.00
556_L	561_Y	1.036	1.00
214_E	217_R	1.032	1.00
330_I	377_I	1.029	1.00
376_L	383_P	1.027	1.00
332_F	373_L	1.025	1.00
162_T	250_C	1.024	1.00
489_L	515_C	1.023	1.00
388_I	395_V	1.019	1.00
448_E	452_K	1.017	1.00
94_Q	98_S	1.017	1.00
366_T	475_R	1.013	1.00
358_E	544_K	1.010	1.00
190_Q	221_A	1.009	1.00
450_I	457_Y	1.009	1.00
16_G	20_I	1.008	1.00
79_H	83_S	1.003	1.00
34_L	38_K	1.000	1.00
258_G	272_V	1.000	1.00
157_F	161_V	0.997	1.00
487_A	515_C	0.997	1.00
226_M	230_V	0.995	1.00
218_F	222_N	0.995	1.00
414_V	477_S	0.994	1.00
95_K	98_S	0.991	1.00
331_E	392_E	0.988	1.00
35_L	55_W	0.986	1.00
220_K	224_R	0.984	1.00
335_V	376_L	0.984	1.00
478_I	491_L	0.984	1.00
445_Q	509_A	0.983	1.00
14_L	79_H	0.979	1.00
361_A	521_T	0.979	1.00
432_A	436_E	0.976	1.00
461_L	467_N	0.975	1.00
423_E	426_A	0.974	1.00
180_L	231_S	0.974	1.00
154_K	266_S	0.972	1.00
371_S	375_Q	0.971	1.00
339_Y	346_A	0.970	1.00
445_Q	508_E	0.969	1.00
455_N	458_D	0.968	1.00
205_I	214_E	0.966	1.00
338_R	346_A	0.966	1.00
21_L	72_L	0.964	1.00
153_V	157_F	0.963	1.00
122_Q	302_S	0.961	1.00
519_I	530_A	0.960	1.00
402_G	405_R	0.960	1.00
119_D	302_S	0.960	1.00
445_Q	512_T	0.959	1.00
330_I	390_I	0.956	1.00
439_D	485_K	0.954	1.00
440_A	483_I	0.953	1.00
536_L	541_L	0.953	1.00
422_K	457_Y	0.951	1.00
231_S	234_Q	0.945	1.00
210_R	214_E	0.943	1.00
390_I	403_L	0.941	1.00
390_I	488_I	0.941	1.00
18_A	77_A	0.940	1.00
259_S	263_T	0.938	1.00
37_A	271_D	0.934	1.00
194_I	217_R	0.931	1.00
12_S	16_G	0.926	1.00
87_D	91_G	0.925	1.00
217_R	221_A	0.924	1.00
213_H	217_R	0.924	1.00
331_E	351_S	0.921	1.00
345_E	385_S	0.916	1.00
437_I	457_Y	0.916	1.00
100_S	315_D	0.916	1.00
505_K	508_E	0.915	1.00
142_A	146_V	0.913	1.00
462_G	466_V	0.910	1.00
425_I	476_I	0.907	1.00
61_G	65_L	0.907	1.00
410_V	478_I	0.906	1.00
13_L	17_I	0.904	1.00
91_G	95_K	0.903	1.00
21_L	76_Y	0.902	1.00
172_W	176_K	0.898	1.00
422_K	438_M	0.898	1.00
151_V	271_D	0.898	1.00
398_I	403_L	0.898	1.00
535_L	556_L	0.897	1.00
180_L	228_K	0.895	1.00
368_S	536_L	0.892	1.00
169_F	242_V	0.891	1.00
451_L	457_Y	0.890	1.00
158_F	257_A	0.889	1.00
523_K	526_T	0.885	1.00
495_T	506_L	0.882	1.00
383_P	396_Q	0.882	1.00
349_N	385_S	0.882	1.00
437_I	483_I	0.881	1.00
145_I	156_G	0.881	1.00
555_Q	558_K	0.880	1.00
183_S	187_R	0.880	1.00
115_R	308_E	0.879	1.00
378_P	490_L	0.877	1.00
338_R	341_E	0.875	1.00
379_R	400_A	0.873	1.00
361_A	533_I	0.873	1.00
182_R	186_K	0.871	1.00
38_K	42_D	0.865	1.00
262_I	267_T	0.864	1.00
387_R	396_Q	0.864	1.00
103_T	107_F	0.862	1.00
92_L	116_L	0.861	1.00
501_Q	505_K	0.861	1.00
54_I	57_T	0.859	1.00
442_K	451_L	0.857	1.00
383_P	388_I	0.856	1.00
549_E	552_S	0.855	1.00
176_K	235_L	0.855	1.00
300_K	304_D	0.855	1.00
402_G	406_Q	0.854	1.00
86_Y	90_K	0.853	1.00
416_L	473_K	0.853	1.00
223_T	226_M	0.852	1.00
219_I	223_T	0.852	1.00
507_L	521_T	0.852	1.00
183_S	231_S	0.851	1.00
461_L	465_G	0.851	1.00
378_P	407_I	0.851	1.00
416_L	476_I	0.848	1.00
444_A	475_R	0.846	1.00
224_R	228_K	0.844	1.00
325_R	391_D	0.843	1.00
541_L	544_K	0.843	1.00
102_S	315_D	0.842	1.00
28_V	65_L	0.840	1.00
443_L	513_Y	0.836	1.00
203_K	375_Q	0.836	1.00
316_E	382_Q	0.836	1.00
176_K	180_L	0.835	1.00
350_V	541_L	0.834	1.00
446_I	476_I	0.833	1.00
395_V	403_L	0.831	1.00
323_S	398_I	0.831	1.00
18_A	80_V	0.829	1.00
486_P	515_C	0.828	1.00
446_I	452_K	0.827	1.00
356_P	391_D	0.826	1.00
148_S	156_G	0.825	1.00
323_S	326_L	0.822	1.00
28_V	69_A	0.821	1.00
558_K	561_Y	0.820	1.00
313_E	317_R	0.816	1.00
306_I	310_L	0.814	1.00
319_E	323_S	0.810	1.00
537_E	540_E	0.810	1.00
11_Y	83_S	0.808	1.00
261_S	264_S	0.807	1.00
167_I	171_L	0.805	1.00
184_V	229_T	0.804	1.00
340_P	344_R	0.804	1.00
213_H	216_K	0.802	1.00
338_R	343_D	0.801	1.00
92_L	306_I	0.800	1.00
41_D	44_I	0.799	1.00
216_K	219_I	0.798	1.00
330_I	488_I	0.798	1.00
112_Y	309_V	0.798	1.00
401_E	405_R	0.798	1.00
204_L	208_L	0.797	1.00
441_A	444_A	0.795	1.00
420_T	423_E	0.795	1.00
217_R	220_K	0.794	1.00
321_T	393_K	0.793	1.00
489_L	517_T	0.790	1.00
336_S	384_D	0.790	1.00
503_E	507_L	0.789	1.00
359_T	511_S	0.787	1.00
35_L	62_L	0.786	1.00
425_I	457_Y	0.785	1.00
28_V	62_L	0.785	1.00
215_V	219_I	0.784	1.00
328_G	516_T	0.784	1.00
333_Q	353_S	0.782	1.00
398_I	402_G	0.782	1.00
443_L	447_H	0.780	1.00
363_L	535_L	0.779	1.00
389_Y	392_E	0.779	1.00
68_A	72_L	0.778	1.00
179_A	183_S	0.775	1.00
507_L	526_T	0.774	1.00
262_I	272_V	0.773	1.00
474_Q	497_A	0.772	1.00
150_A	153_V	0.771	1.00
202_I	206_K	0.768	1.00
26_L	139_L	0.766	1.00
454_P	459_T	0.766	1.00
22_M	136_R	0.766	1.00
338_R	344_R	0.764	1.00
407_I	488_I	0.764	1.00
426_A	430_E	0.764	1.00
56_G	60_I	0.763	1.00
34_L	147_L	0.762	1.00
417_F	424_N	0.762	1.00
152_N	267_T	0.762	1.00
212_S	215_V	0.758	1.00
221_A	224_R	0.755	1.00
35_L	58_V	0.754	1.00
171_L	175_R	0.753	1.00
38_K	55_W	0.753	1.00
102_S	106_Q	0.753	1.00
230_V	234_Q	0.753	1.00
126_M	296_F	0.752	1.00
96_I	104_F	0.752	1.00
111_S	115_R	0.752	1.00
154_K	261_S	0.751	1.00
147_L	151_V	0.749	1.00
426_A	429_K	0.749	1.00
228_K	231_S	0.747	1.00
201_A	204_L	0.746	1.00
126_M	299_A	0.744	1.00
323_S	402_G	0.743	1.00
24_T	65_L	0.743	1.00
470_G	497_A	0.743	1.00
366_T	493_D	0.743	1.00
405_R	484_R	0.743	1.00
426_A	431_N	0.742	1.00
14_L	76_Y	0.742	1.00
38_K	41_D	0.738	1.00
321_T	397_D	0.737	1.00
270_G	274_A	0.736	1.00
154_K	157_F	0.736	1.00
383_P	387_R	0.736	1.00
187_R	221_A	0.735	1.00
137_A	288_M	0.731	1.00
446_I	457_Y	0.731	1.00
413_E	473_K	0.730	1.00
99_F	312_T	0.730	1.00
115_R	119_D	0.729	1.00
453_L	468_L	0.728	1.00
151_V	274_A	0.727	1.00
51_H	54_I	0.727	1.00
58_V	61_G	0.727	1.00
147_L	150_A	0.726	1.00
191_V	225_L	0.726	1.00
95_K	313_E	0.725	1.00
27_A	31_M	0.722	1.00
34_L	37_A	0.721	1.00
316_E	379_R	0.720	1.00
71_M	75_F	0.720	1.00
122_Q	298_R	0.719	1.00
55_W	58_V	0.718	1.00
348_R	538_D	0.717	1.00
434_L	441_A	0.716	1.00
65_L	69_A	0.715	1.00
434_L	457_Y	0.715	1.00
161_V	164_P	0.714	1.00
20_I	24_T	0.714	1.00
418_S	462_G	0.714	1.00
40_I	273_V	0.712	1.00
320_G	402_G	0.711	1.00
156_G	275_I	0.711	1.00
100_S	316_E	0.707	1.00
227_E	231_S	0.706	1.00
325_R	487_A	0.703	1.00
506_L	509_A	0.702	1.00
224_R	227_E	0.702	1.00
149_L	160_L	0.699	1.00
389_Y	394_P	0.699	1.00
551_L	558_K	0.699	1.00
143_G	146_V	0.699	1.00
449_T	452_K	0.698	1.00
261_S	265_G	0.698	1.00
357_R	514_H	0.697	1.00
92_L	310_L	0.696	1.00
57_T	60_I	0.696	1.00
354_A	358_E	0.695	1.00
438_M	450_I	0.694	1.00
495_T	503_E	0.694	1.00
17_I	76_Y	0.691	1.00
258_G	262_I	0.690	1.00
245_L	249_L	0.689	1.00
547_H	561_Y	0.687	1.00
548_S	551_L	0.687	1.00
555_Q	560_I	0.687	1.00
503_E	526_T	0.686	1.00
322_I	402_G	0.686	1.00
88_T	120_V	0.683	1.00
344_R	348_R	0.683	1.00
144_G	281_R	0.683	1.00
320_G	323_S	0.682	1.00
30_L	33_P	0.682	1.00
14_L	83_S	0.682	1.00
360_I	544_K	0.681	1.00
357_R	516_T	0.680	1.00
42_D	51_H	0.679	1.00
155_L	261_S	0.679	1.00
152_N	156_G	0.679	1.00
375_Q	381_Y	0.679	1.00
416_L	461_L	0.679	1.00
429_K	485_K	0.678	1.00
138_P	142_A	0.678	1.00
257_A	260_Y	0.676	1.00
347_L	536_L	0.675	1.00
85_S	124_Q	0.673	1.00
168_L	171_L	0.673	1.00
543_E	550_L	0.672	1.00
185_Q	188_L	0.671	1.00
475_R	502_T	0.671	1.00
183_S	186_K	0.670	1.00
445_Q	448_E	0.668	1.00
490_L	518_L	0.668	1.00
175_R	179_A	0.667	1.00
403_L	407_I	0.667	1.00
553_E	556_L	0.666	1.00
299_A	302_S	0.666	1.00
429_K	484_R	0.665	1.00
91_G	94_Q	0.665	1.00
78_A	129_M	0.665	1.00
337_F	346_A	0.663	1.00
421_I	450_I	0.661	1.00
144_G	282_I	0.661	1.00
376_L	381_Y	0.660	1.00
339_Y	372_T	0.660	1.00
436_E	440_A	0.659	1.00
94_Q	215_V	0.659	1.00
327_S	516_T	0.658	1.00
390_I	395_V	0.658	1.00
532_Q	546_T	0.658	1.00
527_A	530_A	0.658	1.00
304_D	308_E	0.655	1.00
64_V	68_A	0.654	1.00
233_F	237_E	0.650	1.00
374_F	518_L	0.650	1.00
119_D	185_Q	0.649	1.00
91_G	310_L	0.648	1.00
478_I	482_L	0.647	1.00
426_A	441_A	0.647	1.00
114_T	192_N	0.646	1.00
244_M	287_S	0.646	1.00
332_F	350_V	0.645	1.00
362_I	518_L	0.645	1.00
478_I	506_L	0.645	1.00
547_H	550_L	0.642	1.00
543_E	551_L	0.638	1.00
391_D	487_A	0.638	1.00
320_G	399_P	0.637	1.00
475_R	498_L	0.637	1.00
146_V	149_L	0.636	1.00
123_V	303_G	0.635	1.00
419_G	460_V	0.632	1.00
101_Y	105_G	0.631	1.00
22_M	73_N	0.628	1.00
92_L	120_V	0.628	1.00
366_T	521_T	0.628	1.00
34_L	151_V	0.627	1.00
354_A	359_T	0.626	1.00
445_Q	506_L	0.625	1.00
469_S	472_Q	0.625	1.00
111_S	305_R	0.623	1.00
108_S	193_T	0.623	1.00
259_S	262_I	0.622	1.00
554_S	557_Y	0.622	1.00
500_L	503_E	0.621	1.00
144_G	278_Y	0.620	1.00
180_L	183_S	0.620	1.00
413_E	464_R	0.619	1.00
374_F	409_Y	0.618	1.00
471_G	499_D	0.618	1.00
85_S	89_R	0.617	1.00
322_I	399_P	0.617	1.00
532_Q	549_E	0.617	1.00
444_A	478_I	0.617	1.00
189_D	305_R	0.616	1.00
13_L	16_G	0.616	1.00
81_S	128_F	0.616	1.00
352_F	541_L	0.615	1.00
88_T	123_V	0.615	1.00
429_K	433_S	0.614	1.00
543_E	559_R	0.614	1.00
418_S	467_N	0.614	1.00
284_G	288_M	0.613	1.00
331_E	387_R	0.613	1.00
328_G	487_A	0.611	1.00
341_E	345_E	0.611	1.00
535_L	543_E	0.611	1.00
335_V	386_G	0.611	1.00
25_E	70_G	0.610	1.00
181_F	232_A	0.610	1.00
95_K	312_T	0.610	1.00
456_G	459_T	0.608	1.00
125_N	295_I	0.608	1.00
249_L	253_L	0.608	1.00
159_L	279_A	0.608	1.00
237_E	241_P	0.608	1.00
420_T	458_D	0.608	1.00
437_I	440_A	0.606	1.00
355_K	360_I	0.606	1.00
498_L	502_T	0.606	1.00
359_T	529_K	0.606	1.00
408_G	484_R	0.604	1.00
544_K	549_E	0.604	1.00
134_M	138_P	0.603	1.00
51_H	55_W	0.602	1.00
9_K	13_L	0.602	1.00
86_Y	222_N	0.600	1.00
48_D	51_H	0.600	1.00
169_F	246_L	0.600	1.00
383_P	394_P	0.600	1.00
16_G	19_L	0.599	1.00
509_A	513_Y	0.599	1.00
503_E	525_T	0.599	1.00
444_A	482_L	0.599	1.00
554_S	559_R	0.598	1.00
543_E	556_L	0.598	1.00
83_S	86_Y	0.597	1.00
338_R	385_S	0.596	1.00
185_Q	301_A	0.596	1.00
302_S	305_R	0.596	1.00
173_V	239_T	0.596	1.00
31_M	62_L	0.595	1.00
410_V	491_L	0.595	1.00
326_L	406_Q	0.595	1.00
335_V	351_S	0.594	1.00
350_V	536_L	0.594	1.00
123_V	306_I	0.593	1.00
53_W	56_G	0.593	1.00
204_L	207_A	0.593	1.00
443_L	509_A	0.592	1.00
341_E	384_D	0.591	1.00
424_N	476_I	0.590	1.00
442_K	448_E	0.590	1.00
37_A	270_G	0.589	1.00
103_T	112_Y	0.588	1.00
390_I	398_I	0.588	1.00
11_Y	84_F	0.587	1.00
509_A	512_T	0.587	1.00
267_T	272_V	0.587	1.00
494_S	521_T	0.585	1.00
350_V	534_L	0.585	1.00
437_I	441_A	0.584	1.00
93_F	97_Q	0.584	1.00
106_Q	340_P	0.582	1.00
321_T	324_D	0.582	1.00
440_A	479_A	0.581	1.00
152_N	155_L	0.579	1.00
42_D	45_L	0.577	1.00
187_R	225_L	0.576	1.00
538_D	542_I	0.575	1.00
366_T	498_L	0.575	1.00
393_K	402_G	0.575	1.00
114_T	118_N	0.575	1.00
488_I	516_T	0.574	1.00
533_I	546_T	0.574	1.00
507_L	519_I	0.574	1.00
553_E	558_K	0.574	1.00
425_I	428_G	0.573	1.00
114_T	188_L	0.573	1.00
442_K	457_Y	0.573	1.00
183_S	224_R	0.573	1.00
24_T	28_V	0.572	1.00
313_E	316_E	0.572	1.00
345_E	349_N	0.572	1.00
335_V	388_I	0.570	1.00
429_K	483_I	0.570	1.00
164_P	168_L	0.570	1.00
50_R	53_W	0.569	1.00
400_A	403_L	0.568	1.00
528_M	547_H	0.567	1.00
114_T	189_D	0.567	1.00
344_R	538_D	0.566	1.00
410_V	494_S	0.565	1.00
99_F	314_G	0.565	1.00
172_W	175_R	0.564	1.00
375_Q	409_Y	0.564	1.00
499_D	502_T	0.563	1.00
125_N	129_M	0.563	1.00
100_S	103_T	0.562	1.00
121_T	124_Q	0.562	1.00
267_T	271_D	0.561	1.00
439_D	513_Y	0.561	1.00
231_S	235_L	0.560	1.00
167_I	170_L	0.558	1.00
78_A	82_Q	0.558	1.00
258_G	261_S	0.558	1.00
555_Q	559_R	0.557	1.00
69_A	72_L	0.557	1.00
426_A	483_I	0.557	1.00
82_Q	85_S	0.555	1.00
421_I	461_L	0.555	1.00
186_K	190_Q	0.554	1.00
11_Y	14_L	0.554	1.00
25_E	69_A	0.554	1.00
120_V	306_I	0.554	1.00
141_I	145_I	0.553	1.00
447_H	450_I	0.553	1.00
154_K	257_A	0.553	1.00
411_P	414_V	0.553	1.00
450_I	453_L	0.552	1.00
488_I	518_L	0.550	1.00
521_T	525_T	0.547	1.00
372_T	376_L	0.547	1.00
7_F	88_T	0.546	1.00
67_F	71_M	0.546	1.00
101_Y	380_L	0.546	1.00
535_L	542_I	0.543	1.00
508_E	511_S	0.543	1.00
43_G	51_H	0.543	1.00
508_E	529_K	0.542	1.00
194_I	198_N	0.541	1.00
137_A	141_I	0.541	1.00
248_N	252_L	0.540	1.00
133_F	288_M	0.540	1.00
109_S	113_I	0.540	1.00
412_Q	470_G	0.539	1.00
341_E	344_R	0.539	1.00
317_R	399_P	0.539	1.00
502_T	506_L	0.539	1.00
58_V	62_L	0.538	1.00
421_I	446_I	0.536	1.00
519_I	527_A	0.535	1.00
102_S	340_P	0.534	1.00
136_R	140_M	0.534	1.00
482_L	513_Y	0.534	1.00
115_R	305_R	0.533	1.00
326_L	356_P	0.533	1.00
542_I	554_S	0.533	1.00
526_T	530_A	0.532	1.00
354_A	534_L	0.531	1.00
75_F	79_H	0.531	1.00
348_R	351_S	0.531	1.00
321_T	325_R	0.530	1.00
227_E	230_V	0.530	1.00
49_L	53_W	0.528	1.00
363_L	527_A	0.528	1.00
319_E	402_G	0.528	1.00
205_I	211_G	0.527	1.00
371_S	374_F	0.527	1.00
362_I	536_L	0.526	1.00
97_Q	100_S	0.526	1.00
372_T	381_Y	0.526	1.00
34_L	274_A	0.525	1.00
118_N	185_Q	0.524	1.00
104_F	107_F	0.523	1.00
518_L	534_L	0.523	1.00
60_I	64_V	0.523	1.00
44_I	47_Q	0.522	1.00
110_S	193_T	0.522	1.00
478_I	498_L	0.521	1.00
180_L	232_A	0.520	1.00
450_I	454_P	0.520	1.00
29_E	66_S	0.520	1.00
41_D	45_L	0.519	1.00
346_A	350_V	0.518	1.00
14_L	80_V	0.518	1.00
330_I	354_A	0.518	1.00
189_D	301_A	0.517	1.00
116_L	120_V	0.516	1.00
194_I	214_E	0.515	1.00
278_Y	285_A	0.515	1.00
26_L	30_L	0.514	1.00
319_E	397_D	0.513	1.00
148_S	159_L	0.513	1.00
507_L	529_K	0.513	1.00
165_I	168_L	0.513	1.00
160_L	164_P	0.513	1.00
145_I	149_L	0.513	1.00
137_A	289_F	0.512	1.00
72_L	76_Y	0.512	1.00
336_S	347_L	0.511	1.00
359_T	514_H	0.511	1.00
201_A	417_F	0.511	1.00
332_F	376_L	0.511	1.00
424_N	480_R	0.510	1.00
355_K	516_T	0.510	1.00
550_L	557_Y	0.510	1.00
188_L	192_N	0.509	1.00
475_R	497_A	0.509	1.00
471_G	475_R	0.509	1.00
312_T	315_D	0.509	1.00
11_Y	80_V	0.508	1.00
10_P	91_G	0.505	1.00
225_L	229_T	0.504	1.00
551_L	554_S	0.504	1.00
379_R	395_V	0.504	1.00
35_L	59_M	0.503	1.00
319_E	399_P	0.503	1.00
482_L	509_A	0.503	1.00
394_P	398_I	0.503	1.00
129_M	133_F	0.502	1.00
441_A	479_A	0.501	1.00
495_T	498_L	0.501	1.00
153_V	156_G	0.501	1.00
319_E	322_I	0.500	1.00
132_R	135_L	0.500	1.00
537_E	559_R	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4ry2A	2	0.9686	100	0.055	Contact Map
4a82A	2	0.9878	100	0.086	Contact Map
4q4hB	1	0.986	100	0.118	Contact Map
3b5xA	2	0.9878	100	0.123	Contact Map
4f4cA	1	0.9668	100	0.124	Contact Map
3b60A	2	0.9878	100	0.124	Contact Map
4q4hA	1	0.986	100	0.136	Contact Map
3zdqA	2	0.9651	100	0.136	Contact Map
4mrsA	2	0.9983	100	0.141	Contact Map
3wmgA	1	0.9878	100	0.146	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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