GREMLIN Database
PTOCB - PTS system maltose-specific EIICB component
UniProt: P54715 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 527 (478)
Sequences: 2251 (1231)
Seq/√Len: 56.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
289_G395_T5.3861.00
296_V403_R4.9781.00
296_V399_F4.7941.00
403_R407_L4.6351.00
487_P501_R4.5881.00
241_G244_V4.0151.00
412_A418_K3.8521.00
72_I91_L3.8281.00
466_T480_K3.6691.00
388_I392_L3.6531.00
60_W64_N3.6191.00
93_V178_S3.4431.00
302_K305_L3.2111.00
302_K419_D3.1761.00
299_K418_K3.1101.00
344_L401_V3.0631.00
392_L396_A3.0481.00
291_A326_I3.0391.00
297_T407_L2.9871.00
23_G360_N2.9041.00
481_D484_K2.8591.00
294_F310_L2.8421.00
468_V525_L2.7811.00
355_A390_I2.7521.00
297_T403_R2.7351.00
449_D520_R2.6571.00
339_A343_V2.6331.00
470_N514_V2.5721.00
285_F391_G2.5551.00
241_G246_E2.5331.00
405_L409_F2.5221.00
159_K173_Y2.4481.00
284_I318_I2.4471.00
459_L508_V2.4211.00
241_G245_A2.4131.00
486_E490_V2.3791.00
148_I185_I2.3601.00
340_V344_L2.3241.00
219_T349_S2.2141.00
340_V405_L2.2111.00
397_I401_V2.1631.00
458_A490_V2.1611.00
222_E275_G2.1531.00
341_H398_Y2.1261.00
468_V521_V2.1061.00
356_G383_T2.0971.00
490_V493_A2.0911.00
149_V178_S2.0591.00
352_M390_I2.0581.00
11_A78_L2.0571.00
340_V401_V2.0461.00
368_A372_N2.0201.00
456_I525_L2.0081.00
456_I524_I1.9801.00
220_F339_A1.9631.00
350_T354_M1.9531.00
336_F409_F1.9381.00
365_L369_V1.8921.00
68_L91_L1.8821.00
456_I521_V1.8701.00
404_F408_K1.8681.00
147_S151_F1.8610.99
479_V482_E1.8400.99
307_A311_I1.8050.99
500_V509_I1.7970.99
455_Y510_I1.7940.99
30_T56_E1.7860.99
510_I514_V1.7710.99
396_A400_F1.7690.99
220_F342_A1.7610.99
287_I290_I1.7600.99
296_V407_L1.7340.99
451_T513_S1.7290.99
10_S469_T1.7170.99
292_L296_V1.7120.99
467_E478_S1.7040.99
145_I182_M1.6990.99
385_V389_L1.6930.99
187_L191_Y1.6520.99
248_G253_W1.6500.99
148_I181_I1.6250.99
401_V405_L1.6230.99
159_K169_Q1.6230.99
456_I468_V1.6210.99
295_Y307_A1.6090.99
129_I132_I1.5940.98
180_F184_P1.5910.98
482_E506_F1.5770.98
256_H260_Y1.5640.98
13_F232_H1.5620.98
389_L393_S1.5430.98
66_M139_I1.5420.98
257_L272_P1.5250.98
277_A348_M1.5160.98
212_A354_M1.5040.98
160_K163_D1.5010.98
466_T478_S1.5010.98
392_L395_T1.4950.98
152_L181_I1.4910.98
491_F508_V1.4850.97
221_L234_I1.4810.97
457_E490_V1.4780.97
177_I181_I1.4770.97
299_K417_E1.4760.97
304_K307_A1.4730.97
5_I8_F1.4670.97
224_I342_A1.4640.97
295_Y303_K1.4570.97
466_T504_K1.4550.97
386_Y389_L1.4490.97
47_F51_C1.4470.97
278_L345_A1.4460.97
477_V521_V1.4460.97
300_K303_K1.4410.97
29_S59_G1.4400.97
173_Y177_I1.4390.97
496_A499_V1.4380.97
479_V485_V1.4380.97
459_L477_V1.4290.97
21_F179_F1.4270.97
145_I185_I1.4160.97
368_A389_L1.4150.97
213_V217_I1.4150.97
220_F224_I1.3910.96
256_H259_E1.3860.96
404_F409_F1.3840.96
93_V145_I1.3800.96
482_E504_K1.3750.96
78_L147_S1.3720.96
412_A417_E1.3710.96
352_M357_V1.3670.96
463_D484_K1.3650.96
283_K317_A1.3650.96
518_R522_E1.3610.96
291_A310_L1.3610.96
81_K153_H1.3600.96
406_I413_T1.3560.96
413_T416_R1.3460.95
256_H261_S1.3450.95
156_Y177_I1.3310.95
494_L510_I1.3310.95
372_N384_Y1.3290.95
482_E501_R1.3260.95
459_L521_V1.3200.95
218_Y273_Q1.3090.95
152_L177_I1.3080.95
212_A350_T1.2920.94
470_N494_L1.2870.94
152_L173_Y1.2810.94
91_L95_L1.2760.94
351_V354_M1.2710.94
311_I314_T1.2690.94
292_L395_T1.2520.93
331_L338_F1.2460.93
249_I252_Y1.2450.93
458_A494_L1.2420.93
295_Y310_L1.2360.93
294_F297_T1.2360.93
184_P188_A1.2300.93
494_L514_V1.2290.93
318_I365_L1.2270.93
454_L490_V1.2270.93
472_A514_V1.2230.93
381_G384_Y1.2130.92
259_E264_A1.2120.92
470_N517_M1.2060.92
14_V76_V1.2040.92
306_V310_L1.2030.92
302_K417_E1.1930.92
148_I151_F1.1780.91
405_L411_I1.1760.91
447_T450_D1.1580.90
76_V87_C1.1440.90
451_T517_M1.1290.89
57_Q103_A1.1280.89
515_P519_E1.1270.89
357_V386_Y1.1210.89
222_E345_A1.1150.89
348_M394_F1.1100.88
100_F186_A1.1100.88
399_F403_R1.1070.88
355_A386_Y1.1040.88
294_F306_V1.1030.88
298_A413_T1.1000.88
242_P246_E1.0980.88
487_P492_R1.0960.88
216_W350_T1.0850.87
255_Q258_G1.0840.87
211_G214_G1.0830.87
215_V270_L1.0790.87
220_F343_V1.0760.87
399_F407_L1.0760.87
296_V300_K1.0740.87
250_V253_W1.0680.86
216_W220_F1.0670.86
336_F339_A1.0660.86
93_V182_M1.0640.86
336_F340_V1.0610.86
400_F404_F1.0590.86
259_E265_K1.0580.86
290_I294_F1.0510.85
267_L270_L1.0510.85
520_R523_K1.0460.85
452_A524_I1.0420.85
389_L392_L1.0410.85
514_V517_M1.0370.85
126_L131_G1.0330.84
177_I180_F1.0280.84
455_Y517_M1.0240.84
206_F210_S1.0230.84
277_A352_M1.0220.84
309_L313_V1.0180.84
296_V303_K1.0140.83
485_V506_F1.0140.83
215_V353_Y1.0140.83
347_T394_F1.0130.83
451_T494_L1.0120.83
478_S505_A1.0110.83
166_G322_I1.0050.83
358_V371_L1.0050.83
502_N505_A1.0030.83
256_H272_P1.0020.83
132_I135_L1.0010.82
453_F457_E0.9980.82
347_T351_V0.9950.82
158_D523_K0.9930.82
216_W347_T0.9930.82
468_V522_E0.9910.82
486_E489_S0.9850.81
292_L297_T0.9830.81
406_I416_R0.9770.81
18_L92_T0.9710.81
257_L261_S0.9650.80
26_V63_F0.9650.80
145_I149_V0.9620.80
265_K268_K0.9590.80
102_S106_T0.9580.80
319_V366_I0.9540.79
278_L394_F0.9540.79
388_I393_S0.9510.79
486_E491_F0.9500.79
458_A491_F0.9500.79
497_H510_I0.9490.79
287_I326_I0.9440.79
72_I87_C0.9430.79
57_Q60_W0.9420.78
278_L286_G0.9410.78
298_A303_K0.9410.78
94_Y98_N0.9380.78
24_I28_I0.9360.78
489_S493_A0.9340.78
255_Q259_E0.9310.78
404_F411_I0.9280.77
383_T386_Y0.9250.77
199_G202_S0.9180.77
244_V250_V0.9170.77
322_I472_A0.9170.77
239_I362_G0.9160.76
397_I400_F0.9120.76
372_N380_H0.9100.76
95_L130_A0.9050.76
97_F141_G0.9050.76
372_N385_V0.9040.76
153_H269_E0.9010.75
28_I32_F0.8960.75
352_M356_G0.8960.75
286_G398_Y0.8910.74
450_D453_F0.8890.74
247_G250_V0.8860.74
93_V149_V0.8850.74
75_P90_A0.8850.74
482_E502_N0.8840.74
482_E503_G0.8830.74
292_L295_Y0.8830.74
148_I182_M0.8790.73
336_F405_L0.8780.73
521_V524_I0.8770.73
454_L494_L0.8750.73
23_G316_T0.8750.73
480_K484_K0.8710.73
188_A192_I0.8710.73
359_G367_E0.8710.73
516_Q519_E0.8700.73
442_A445_A0.8680.73
301_E419_D0.8680.73
300_K399_F0.8640.72
308_G326_I0.8620.72
465_I525_L0.8570.72
283_K363_G0.8570.72
126_L133_K0.8570.72
358_V387_Q0.8550.71
344_L347_T0.8550.71
454_L457_E0.8530.71
3_Q505_A0.8500.71
470_N518_R0.8500.71
393_S493_A0.8490.71
4_K8_F0.8490.71
368_A385_V0.8490.71
243_A246_E0.8460.71
477_V508_V0.8420.70
302_K420_E0.8410.70
26_V366_I0.8400.70
159_K177_I0.8400.70
410_N416_R0.8390.70
479_V487_P0.8390.70
446_E520_R0.8380.70
368_A384_Y0.8370.70
33_K36_T0.8350.70
248_G255_Q0.8350.70
241_G250_V0.8340.69
208_V238_F0.8340.69
152_L156_Y0.8340.69
276_F283_K0.8330.69
254_A258_G0.8310.69
111_A133_K0.8310.69
131_G135_L0.8300.69
295_Y311_I0.8300.69
6_Q77_A0.8270.69
284_I391_G0.8270.69
125_G129_I0.8270.69
164_F315_L0.8260.69
320_A364_G0.8260.69
400_F403_R0.8240.69
128_M132_I0.8230.68
470_N516_Q0.8220.68
131_G134_T0.8210.68
33_K56_E0.8190.68
351_V394_F0.8160.68
172_T175_V0.8150.68
128_M131_G0.8120.67
75_P86_A0.8120.67
126_L129_I0.8090.67
53_Y56_E0.8040.67
12_M171_S0.8030.67
75_P150_V0.8020.66
499_V508_V0.8010.66
212_A353_Y0.8010.66
205_S209_A0.7980.66
210_S217_I0.7970.66
292_L403_R0.7970.66
219_T346_A0.7950.66
452_A520_R0.7880.65
497_H513_S0.7790.64
455_Y491_F0.7770.64
62_V69_L0.7770.64
162_P165_L0.7750.64
465_I479_V0.7750.64
299_K419_D0.7710.63
443_S446_E0.7710.63
443_S457_E0.7700.63
68_L130_A0.7690.63
410_N413_T0.7670.63
97_F189_V0.7640.63
97_F186_A0.7620.62
258_G261_S0.7600.62
406_I415_G0.7580.62
510_I517_M0.7570.62
259_E268_K0.7560.62
245_A252_Y0.7550.62
470_N515_P0.7550.62
463_D480_K0.7530.62
239_I361_M0.7530.62
454_L493_A0.7520.61
213_V422_Q0.7520.61
140_I237_P0.7490.61
222_E349_S0.7490.61
4_K151_F0.7470.61
84_A289_G0.7430.61
351_V390_I0.7430.61
457_E509_I0.7410.60
199_G203_L0.7400.60
215_V220_F0.7390.60
192_I195_M0.7390.60
7_R154_N0.7380.60
198_S202_S0.7370.60
33_K52_W0.7360.60
179_F182_M0.7340.60
470_N510_I0.7310.59
443_S463_D0.7300.59
305_L408_K0.7290.59
275_G331_L0.7290.59
351_V355_A0.7250.59
275_G349_S0.7240.59
30_T37_L0.7240.59
6_Q9_G0.7230.58
162_P168_F0.7230.58
220_F346_A0.7200.58
290_I402_F0.7190.58
27_G30_T0.7190.58
7_R467_E0.7180.58
468_V477_V0.7180.58
289_G396_A0.7180.58
127_T136_D0.7170.58
242_P245_A0.7170.58
472_A512_L0.7160.58
38_M48_W0.7160.58
278_L348_M0.7130.57
137_T141_G0.7130.57
456_I465_I0.7130.57
259_E266_P0.7120.57
270_L353_Y0.7090.57
454_L524_I0.7090.57
327_E330_F0.7080.57
299_K412_A0.7080.57
469_T518_R0.7070.57
101_V137_T0.7050.57
32_F38_M0.7030.56
297_T303_K0.6990.56
263_S266_P0.6990.56
104_I187_L0.6980.56
491_F499_V0.6980.56
271_F274_G0.6970.56
81_K523_K0.6950.55
302_K509_I0.6950.55
458_A486_E0.6940.55
392_L442_A0.6930.55
83_Q171_S0.6930.55
253_W256_H0.6910.55
291_A314_T0.6900.55
275_G338_F0.6900.55
477_V518_R0.6880.55
417_E420_E0.6870.55
82_A157_F0.6860.54
71_A142_A0.6850.54
453_F524_I0.6850.54
287_I313_V0.6840.54
314_T318_I0.6840.54
466_T479_V0.6810.54
222_E278_L0.6800.54
448_A516_Q0.6800.54
24_I352_M0.6790.54
508_V517_M0.6770.53
26_V60_W0.6770.53
299_K405_L0.6750.53
249_I253_W0.6740.53
256_H384_Y0.6720.53
520_R524_I0.6720.53
68_L95_L0.6690.53
472_A497_H0.6690.53
129_I135_L0.6680.53
465_I468_V0.6680.53
239_I363_G0.6670.52
104_I190_S0.6660.52
126_L130_A0.6660.52
181_I185_I0.6660.52
287_I398_Y0.6640.52
140_I191_Y0.6630.52
347_T383_T0.6630.52
150_V154_N0.6610.52
129_I133_K0.6610.52
3_Q451_T0.6610.52
344_L404_F0.6570.51
57_Q64_N0.6560.51
228_T331_L0.6550.51
483_T493_A0.6550.51
290_I412_A0.6550.51
144_F217_I0.6550.51
286_G341_H0.6540.51
255_Q260_Y0.6540.51
448_A514_V0.6530.51
192_I196_V0.6510.51
404_F407_L0.6500.51
53_Y57_Q0.6500.51
313_V317_A0.6480.50
327_E341_H0.6480.50
3_Q478_S0.6470.50
508_V514_V0.6460.50
421_Q493_A0.6460.50
254_A261_S0.6450.50
206_F209_A0.6450.50
30_T34_N0.6440.50
515_P522_E0.6430.50
290_I398_Y0.6430.50
296_V400_F0.6420.50
475_L518_R0.6420.50
367_E370_T0.6420.50
144_F189_V0.6400.49
111_A126_L0.6390.49
198_S343_V0.6390.49
73_G88_L0.6380.49
94_Y141_G0.6370.49
216_W346_A0.6370.49
304_K404_F0.6350.49
239_I283_K0.6340.49
354_M457_E0.6320.49
169_Q496_A0.6310.48
451_T454_L0.6310.48
455_Y494_L0.6300.48
478_S504_K0.6300.48
462_K509_I0.6290.48
512_L516_Q0.6280.48
237_P395_T0.6280.48
287_I341_H0.6270.48
458_A470_N0.6260.48
491_F496_A0.6260.48
445_A448_A0.6240.48
275_G345_A0.6210.47
516_Q520_R0.6200.47
300_K304_K0.6200.47
163_D513_S0.6190.47
9_G12_M0.6170.47
128_M133_K0.6150.47
334_S411_I0.6150.47
297_T418_K0.6130.47
451_T455_Y0.6130.47
264_A268_K0.6120.46
448_A520_R0.6120.46
408_K523_K0.6110.46
284_I341_H0.6100.46
85_R518_R0.6100.46
221_L346_A0.6100.46
235_Y345_A0.6080.46
135_L197_Q0.6070.46
293_A406_I0.6070.46
451_T500_V0.6070.46
269_E272_P0.6060.46
252_Y256_H0.6060.46
512_L519_E0.6050.46
316_T329_T0.6050.46
448_A451_T0.6050.46
80_K467_E0.6040.46
298_A416_R0.6040.46
156_Y173_Y0.6020.45
178_S182_M0.6020.45
251_T255_Q0.6010.45
139_I142_A0.6010.45
152_L182_M0.6000.45
385_V505_A0.6000.45
448_A513_S0.5990.45
33_K37_L0.5980.45
286_G401_V0.5980.45
16_V30_T0.5960.45
239_I276_F0.5960.45
201_G205_S0.5960.45
2_M502_N0.5960.45
303_K356_G0.5940.44
487_P490_V0.5940.44
352_M387_Q0.5940.44
462_K525_L0.5930.44
322_I409_F0.5920.44
51_C449_D0.5920.44
204_Q331_L0.5910.44
215_V309_L0.5910.44
301_E420_E0.5910.44
31_L38_M0.5910.44
76_V83_Q0.5900.44
307_A361_M0.5900.44
17_L167_I0.5900.44
408_K440_E0.5900.44
334_S409_F0.5900.44
410_N417_E0.5890.44
56_E60_W0.5870.44
513_S516_Q0.5870.44
63_F322_I0.5860.44
188_A191_Y0.5860.44
289_G368_A0.5860.44
406_I414_P0.5850.44
21_F178_S0.5840.43
8_F157_F0.5830.43
31_L37_L0.5810.43
459_L479_V0.5810.43
38_M52_W0.5800.43
477_V502_N0.5800.43
84_A88_L0.5790.43
55_I379_S0.5780.43
81_K158_D0.5780.43
76_V503_G0.5770.43
297_T411_I0.5760.43
97_F145_I0.5760.43
442_A450_D0.5760.43
357_V389_L0.5750.42
504_K517_M0.5730.42
218_Y304_K0.5730.42
485_V499_V0.5730.42
287_I317_A0.5720.42
336_F411_I0.5720.42
142_A146_S0.5710.42
94_Y140_I0.5690.42
273_Q352_M0.5680.42
218_Y338_F0.5680.42
441_T445_A0.5670.42
458_A477_V0.5670.42
299_K420_E0.5670.42
197_Q271_F0.5660.42
284_I368_A0.5660.42
151_F156_Y0.5650.41
362_G367_E0.5640.41
420_E489_S0.5630.41
58_G100_F0.5620.41
251_T254_A0.5620.41
250_V255_Q0.5610.41
310_L493_A0.5600.41
51_C443_S0.5600.41
236_T242_P0.5600.41
357_V390_I0.5590.41
273_Q276_F0.5580.41
160_K513_S0.5580.41
514_V521_V0.5570.41
87_C90_A0.5570.41
17_L239_I0.5550.40
310_L329_T0.5540.40
222_E342_A0.5540.40
508_V521_V0.5540.40
485_V508_V0.5530.40
207_L238_F0.5530.40
473_T509_I0.5520.40
275_G278_L0.5520.40
153_H171_S0.5520.40
33_K38_M0.5510.40
380_H384_Y0.5510.40
500_V521_V0.5500.40
276_F371_L0.5500.40
245_A249_I0.5480.40
446_E449_D0.5480.40
180_F483_T0.5470.40
297_T399_F0.5470.40
98_N132_I0.5460.39
35_K39_G0.5450.39
71_A228_T0.5450.39
224_I339_A0.5440.39
38_M56_E0.5440.39
245_A250_V0.5440.39
454_L462_K0.5430.39
29_S361_M0.5430.39
277_A283_K0.5430.39
223_R323_T0.5410.39
21_F180_F0.5410.39
390_I394_F0.5410.39
466_T484_K0.5410.39
192_I205_S0.5410.39
310_L413_T0.5410.39
494_L521_V0.5400.39
456_I499_V0.5390.39
141_G228_T0.5390.39
456_I463_D0.5380.39
80_K154_N0.5380.39
165_L177_I0.5370.38
301_E418_K0.5370.38
444_A523_K0.5370.38
151_F483_T0.5370.38
77_A238_F0.5360.38
63_F372_N0.5350.38
248_G251_T0.5340.38
253_W260_Y0.5340.38
238_F272_P0.5330.38
101_V190_S0.5330.38
443_S483_T0.5320.38
20_A223_R0.5310.38
356_G382_M0.5300.38
228_T348_M0.5290.38
17_L331_L0.5280.38
265_K303_K0.5270.37
333_I336_F0.5260.37
235_Y275_G0.5260.37
48_W52_W0.5260.37
32_F35_K0.5260.37
346_A349_S0.5250.37
453_F483_T0.5250.37
32_F52_W0.5250.37
272_P276_F0.5250.37
290_I341_H0.5240.37
445_A449_D0.5240.37
250_V254_A0.5230.37
440_E444_A0.5230.37
219_T345_A0.5220.37
236_T239_I0.5210.37
459_L506_F0.5200.37
491_F512_L0.5200.37
156_Y159_K0.5200.37
457_E484_K0.5190.37
398_Y402_F0.5190.37
521_V525_L0.5190.37
60_W213_V0.5190.37
78_L166_G0.5190.37
288_P291_A0.5170.36
83_Q153_H0.5170.36
99_Y102_S0.5160.36
159_K199_G0.5160.36
478_S482_E0.5150.36
443_S490_V0.5150.36
199_G421_Q0.5150.36
343_V404_F0.5140.36
112_F128_M0.5140.36
62_V96_T0.5140.36
95_L400_F0.5140.36
284_I363_G0.5130.36
18_L256_H0.5120.36
287_I320_A0.5110.36
98_N135_L0.5110.36
329_T339_A0.5100.36
340_V393_S0.5100.36
246_E251_T0.5090.36
90_A501_R0.5090.36
92_T152_L0.5080.36
421_Q442_A0.5080.36
514_V519_E0.5080.36
165_L361_M0.5080.36
348_M352_M0.5070.35
380_H383_T0.5060.35
186_A322_I0.5060.35
442_A447_T0.5060.35
182_M186_A0.5050.35
268_K271_F0.5040.35
510_I513_S0.5040.35
63_F316_T0.5040.35
226_I345_A0.5040.35
360_N363_G0.5030.35
79_A234_I0.5030.35
313_V329_T0.5030.35
215_V221_L0.5020.35
184_P493_A0.5020.35
185_I189_V0.5010.35
149_V177_I0.5010.35
73_G276_F0.5010.35
394_F397_I0.5000.35
74_I143_I0.5000.35
127_T131_G0.5000.35
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3qnqA 2 0.7362 100 0.7 Contact Map
1ibaA 1 0.1442 99.9 0.839 Contact Map
3bp3A 1 0.1537 99.9 0.844 Contact Map
3ipjA 1 0.1556 99.9 0.855 Contact Map
4pypA 1 0.6793 42.8 0.977 Contact Map
3wdoA 1 0.7419 28.9 0.979 Contact Map
4ea3A 2 0.1556 28.1 0.979 Contact Map
4jkvA 2 0.1385 27.2 0.979 Contact Map
3w9iA 3 0.2619 23.2 0.98 Contact Map
4mt1A 3 0.2562 15.7 0.981 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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