PTOCB - BACSU - GREMLIN Contacts

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PTOCB - PTS system maltose-specific EIICB component

UniProt:	P54715	Sequences: MMQKIQRFGSAMFVPVLLFAFAGIIVGISTLFKNKTLMGPLADPDGFWYQCWYIIEQGGWTVFNQMPLLFAIGIPVALAKKAQARACLEALTVYLTFNYFVSAILTVWGGAFGVDMNQEVGGTSGLTMIAGIKTLDTNIIGAIFISSIVVFLHNRYFDKKLPDFLGIFQGSTYIVMISFFIMIPIALAVSYIWPMVQSGIGSLQSFLVASGAVGVWIYTFLERILIPTGLHHFIYTPFIYGPAVAEGGIVTYWAQHLGEYSQSAKPLKELFPQGGFALHGNSKIFGIPGIALAFYVTAKKEKKKLVAGLLIPVTLTAIVAGITEPIEFTFLFISPFLFAVHAVLAATMSTVMYMAGVVGNMGGGLIEAVTLNWIPLFGSHGMTYVYQILIGLSFTAIYFFVFRFLILKFNIATPGREKDEQQETKLYSKKEYRERKNKDETASAAETADDTAFLYIEALGGKDNITEVTNCATRLRVSVKDETKVEPDSVFRALGAHGVVRNGKAFQVIIGLSVPQMRERVEKILNQ	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	527 (478)
Sequences:	2251 (1231)
Seq/√Len:	56.3

ECOLI - PTW3C PTOCB PTGCB PTXC
BACSU - PTOCB PTG3C PTW3C PTWCB

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
289_G	395_T	5.386	1.00
296_V	403_R	4.978	1.00
296_V	399_F	4.794	1.00
403_R	407_L	4.635	1.00
487_P	501_R	4.588	1.00
241_G	244_V	4.015	1.00
412_A	418_K	3.852	1.00
72_I	91_L	3.828	1.00
466_T	480_K	3.669	1.00
388_I	392_L	3.653	1.00
60_W	64_N	3.619	1.00
93_V	178_S	3.443	1.00
302_K	305_L	3.211	1.00
302_K	419_D	3.176	1.00
299_K	418_K	3.110	1.00
344_L	401_V	3.063	1.00
392_L	396_A	3.048	1.00
291_A	326_I	3.039	1.00
297_T	407_L	2.987	1.00
23_G	360_N	2.904	1.00
481_D	484_K	2.859	1.00
294_F	310_L	2.842	1.00
468_V	525_L	2.781	1.00
355_A	390_I	2.752	1.00
297_T	403_R	2.735	1.00
449_D	520_R	2.657	1.00
339_A	343_V	2.633	1.00
470_N	514_V	2.572	1.00
285_F	391_G	2.555	1.00
241_G	246_E	2.533	1.00
405_L	409_F	2.522	1.00
159_K	173_Y	2.448	1.00
284_I	318_I	2.447	1.00
459_L	508_V	2.421	1.00
241_G	245_A	2.413	1.00
486_E	490_V	2.379	1.00
148_I	185_I	2.360	1.00
340_V	344_L	2.324	1.00
219_T	349_S	2.214	1.00
340_V	405_L	2.211	1.00
397_I	401_V	2.163	1.00
458_A	490_V	2.161	1.00
222_E	275_G	2.153	1.00
341_H	398_Y	2.126	1.00
468_V	521_V	2.106	1.00
356_G	383_T	2.097	1.00
490_V	493_A	2.091	1.00
149_V	178_S	2.059	1.00
352_M	390_I	2.058	1.00
11_A	78_L	2.057	1.00
340_V	401_V	2.046	1.00
368_A	372_N	2.020	1.00
456_I	525_L	2.008	1.00
456_I	524_I	1.980	1.00
220_F	339_A	1.963	1.00
350_T	354_M	1.953	1.00
336_F	409_F	1.938	1.00
365_L	369_V	1.892	1.00
68_L	91_L	1.882	1.00
456_I	521_V	1.870	1.00
404_F	408_K	1.868	1.00
147_S	151_F	1.861	0.99
479_V	482_E	1.840	0.99
307_A	311_I	1.805	0.99
500_V	509_I	1.797	0.99
455_Y	510_I	1.794	0.99
30_T	56_E	1.786	0.99
510_I	514_V	1.771	0.99
396_A	400_F	1.769	0.99
220_F	342_A	1.761	0.99
287_I	290_I	1.760	0.99
296_V	407_L	1.734	0.99
451_T	513_S	1.729	0.99
10_S	469_T	1.717	0.99
292_L	296_V	1.712	0.99
467_E	478_S	1.704	0.99
145_I	182_M	1.699	0.99
385_V	389_L	1.693	0.99
187_L	191_Y	1.652	0.99
248_G	253_W	1.650	0.99
148_I	181_I	1.625	0.99
401_V	405_L	1.623	0.99
159_K	169_Q	1.623	0.99
456_I	468_V	1.621	0.99
295_Y	307_A	1.609	0.99
129_I	132_I	1.594	0.98
180_F	184_P	1.591	0.98
482_E	506_F	1.577	0.98
256_H	260_Y	1.564	0.98
13_F	232_H	1.562	0.98
389_L	393_S	1.543	0.98
66_M	139_I	1.542	0.98
257_L	272_P	1.525	0.98
277_A	348_M	1.516	0.98
212_A	354_M	1.504	0.98
160_K	163_D	1.501	0.98
466_T	478_S	1.501	0.98
392_L	395_T	1.495	0.98
152_L	181_I	1.491	0.98
491_F	508_V	1.485	0.97
221_L	234_I	1.481	0.97
457_E	490_V	1.478	0.97
177_I	181_I	1.477	0.97
299_K	417_E	1.476	0.97
304_K	307_A	1.473	0.97
5_I	8_F	1.467	0.97
224_I	342_A	1.464	0.97
295_Y	303_K	1.457	0.97
466_T	504_K	1.455	0.97
386_Y	389_L	1.449	0.97
47_F	51_C	1.447	0.97
278_L	345_A	1.446	0.97
477_V	521_V	1.446	0.97
300_K	303_K	1.441	0.97
29_S	59_G	1.440	0.97
173_Y	177_I	1.439	0.97
496_A	499_V	1.438	0.97
479_V	485_V	1.438	0.97
459_L	477_V	1.429	0.97
21_F	179_F	1.427	0.97
145_I	185_I	1.416	0.97
368_A	389_L	1.415	0.97
213_V	217_I	1.415	0.97
220_F	224_I	1.391	0.96
256_H	259_E	1.386	0.96
404_F	409_F	1.384	0.96
93_V	145_I	1.380	0.96
482_E	504_K	1.375	0.96
78_L	147_S	1.372	0.96
412_A	417_E	1.371	0.96
352_M	357_V	1.367	0.96
463_D	484_K	1.365	0.96
283_K	317_A	1.365	0.96
518_R	522_E	1.361	0.96
291_A	310_L	1.361	0.96
81_K	153_H	1.360	0.96
406_I	413_T	1.356	0.96
413_T	416_R	1.346	0.95
256_H	261_S	1.345	0.95
156_Y	177_I	1.331	0.95
494_L	510_I	1.331	0.95
372_N	384_Y	1.329	0.95
482_E	501_R	1.326	0.95
459_L	521_V	1.320	0.95
218_Y	273_Q	1.309	0.95
152_L	177_I	1.308	0.95
212_A	350_T	1.292	0.94
470_N	494_L	1.287	0.94
152_L	173_Y	1.281	0.94
91_L	95_L	1.276	0.94
351_V	354_M	1.271	0.94
311_I	314_T	1.269	0.94
292_L	395_T	1.252	0.93
331_L	338_F	1.246	0.93
249_I	252_Y	1.245	0.93
458_A	494_L	1.242	0.93
295_Y	310_L	1.236	0.93
294_F	297_T	1.236	0.93
184_P	188_A	1.230	0.93
494_L	514_V	1.229	0.93
318_I	365_L	1.227	0.93
454_L	490_V	1.227	0.93
472_A	514_V	1.223	0.93
381_G	384_Y	1.213	0.92
259_E	264_A	1.212	0.92
470_N	517_M	1.206	0.92
14_V	76_V	1.204	0.92
306_V	310_L	1.203	0.92
302_K	417_E	1.193	0.92
148_I	151_F	1.178	0.91
405_L	411_I	1.176	0.91
447_T	450_D	1.158	0.90
76_V	87_C	1.144	0.90
451_T	517_M	1.129	0.89
57_Q	103_A	1.128	0.89
515_P	519_E	1.127	0.89
357_V	386_Y	1.121	0.89
222_E	345_A	1.115	0.89
348_M	394_F	1.110	0.88
100_F	186_A	1.110	0.88
399_F	403_R	1.107	0.88
355_A	386_Y	1.104	0.88
294_F	306_V	1.103	0.88
298_A	413_T	1.100	0.88
242_P	246_E	1.098	0.88
487_P	492_R	1.096	0.88
216_W	350_T	1.085	0.87
255_Q	258_G	1.084	0.87
211_G	214_G	1.083	0.87
215_V	270_L	1.079	0.87
220_F	343_V	1.076	0.87
399_F	407_L	1.076	0.87
296_V	300_K	1.074	0.87
250_V	253_W	1.068	0.86
216_W	220_F	1.067	0.86
336_F	339_A	1.066	0.86
93_V	182_M	1.064	0.86
336_F	340_V	1.061	0.86
400_F	404_F	1.059	0.86
259_E	265_K	1.058	0.86
290_I	294_F	1.051	0.85
267_L	270_L	1.051	0.85
520_R	523_K	1.046	0.85
452_A	524_I	1.042	0.85
389_L	392_L	1.041	0.85
514_V	517_M	1.037	0.85
126_L	131_G	1.033	0.84
177_I	180_F	1.028	0.84
455_Y	517_M	1.024	0.84
206_F	210_S	1.023	0.84
277_A	352_M	1.022	0.84
309_L	313_V	1.018	0.84
296_V	303_K	1.014	0.83
485_V	506_F	1.014	0.83
215_V	353_Y	1.014	0.83
347_T	394_F	1.013	0.83
451_T	494_L	1.012	0.83
478_S	505_A	1.011	0.83
166_G	322_I	1.005	0.83
358_V	371_L	1.005	0.83
502_N	505_A	1.003	0.83
256_H	272_P	1.002	0.83
132_I	135_L	1.001	0.82
453_F	457_E	0.998	0.82
347_T	351_V	0.995	0.82
158_D	523_K	0.993	0.82
216_W	347_T	0.993	0.82
468_V	522_E	0.991	0.82
486_E	489_S	0.985	0.81
292_L	297_T	0.983	0.81
406_I	416_R	0.977	0.81
18_L	92_T	0.971	0.81
257_L	261_S	0.965	0.80
26_V	63_F	0.965	0.80
145_I	149_V	0.962	0.80
265_K	268_K	0.959	0.80
102_S	106_T	0.958	0.80
319_V	366_I	0.954	0.79
278_L	394_F	0.954	0.79
388_I	393_S	0.951	0.79
486_E	491_F	0.950	0.79
458_A	491_F	0.950	0.79
497_H	510_I	0.949	0.79
287_I	326_I	0.944	0.79
72_I	87_C	0.943	0.79
57_Q	60_W	0.942	0.78
278_L	286_G	0.941	0.78
298_A	303_K	0.941	0.78
94_Y	98_N	0.938	0.78
24_I	28_I	0.936	0.78
489_S	493_A	0.934	0.78
255_Q	259_E	0.931	0.78
404_F	411_I	0.928	0.77
383_T	386_Y	0.925	0.77
199_G	202_S	0.918	0.77
244_V	250_V	0.917	0.77
322_I	472_A	0.917	0.77
239_I	362_G	0.916	0.76
397_I	400_F	0.912	0.76
372_N	380_H	0.910	0.76
95_L	130_A	0.905	0.76
97_F	141_G	0.905	0.76
372_N	385_V	0.904	0.76
153_H	269_E	0.901	0.75
28_I	32_F	0.896	0.75
352_M	356_G	0.896	0.75
286_G	398_Y	0.891	0.74
450_D	453_F	0.889	0.74
247_G	250_V	0.886	0.74
93_V	149_V	0.885	0.74
75_P	90_A	0.885	0.74
482_E	502_N	0.884	0.74
482_E	503_G	0.883	0.74
292_L	295_Y	0.883	0.74
148_I	182_M	0.879	0.73
336_F	405_L	0.878	0.73
521_V	524_I	0.877	0.73
454_L	494_L	0.875	0.73
23_G	316_T	0.875	0.73
480_K	484_K	0.871	0.73
188_A	192_I	0.871	0.73
359_G	367_E	0.871	0.73
516_Q	519_E	0.870	0.73
442_A	445_A	0.868	0.73
301_E	419_D	0.868	0.73
300_K	399_F	0.864	0.72
308_G	326_I	0.862	0.72
465_I	525_L	0.857	0.72
283_K	363_G	0.857	0.72
126_L	133_K	0.857	0.72
358_V	387_Q	0.855	0.71
344_L	347_T	0.855	0.71
454_L	457_E	0.853	0.71
3_Q	505_A	0.850	0.71
470_N	518_R	0.850	0.71
393_S	493_A	0.849	0.71
4_K	8_F	0.849	0.71
368_A	385_V	0.849	0.71
243_A	246_E	0.846	0.71
477_V	508_V	0.842	0.70
302_K	420_E	0.841	0.70
26_V	366_I	0.840	0.70
159_K	177_I	0.840	0.70
410_N	416_R	0.839	0.70
479_V	487_P	0.839	0.70
446_E	520_R	0.838	0.70
368_A	384_Y	0.837	0.70
33_K	36_T	0.835	0.70
248_G	255_Q	0.835	0.70
241_G	250_V	0.834	0.69
208_V	238_F	0.834	0.69
152_L	156_Y	0.834	0.69
276_F	283_K	0.833	0.69
254_A	258_G	0.831	0.69
111_A	133_K	0.831	0.69
131_G	135_L	0.830	0.69
295_Y	311_I	0.830	0.69
6_Q	77_A	0.827	0.69
284_I	391_G	0.827	0.69
125_G	129_I	0.827	0.69
164_F	315_L	0.826	0.69
320_A	364_G	0.826	0.69
400_F	403_R	0.824	0.69
128_M	132_I	0.823	0.68
470_N	516_Q	0.822	0.68
131_G	134_T	0.821	0.68
33_K	56_E	0.819	0.68
351_V	394_F	0.816	0.68
172_T	175_V	0.815	0.68
128_M	131_G	0.812	0.67
75_P	86_A	0.812	0.67
126_L	129_I	0.809	0.67
53_Y	56_E	0.804	0.67
12_M	171_S	0.803	0.67
75_P	150_V	0.802	0.66
499_V	508_V	0.801	0.66
212_A	353_Y	0.801	0.66
205_S	209_A	0.798	0.66
210_S	217_I	0.797	0.66
292_L	403_R	0.797	0.66
219_T	346_A	0.795	0.66
452_A	520_R	0.788	0.65
497_H	513_S	0.779	0.64
455_Y	491_F	0.777	0.64
62_V	69_L	0.777	0.64
162_P	165_L	0.775	0.64
465_I	479_V	0.775	0.64
299_K	419_D	0.771	0.63
443_S	446_E	0.771	0.63
443_S	457_E	0.770	0.63
68_L	130_A	0.769	0.63
410_N	413_T	0.767	0.63
97_F	189_V	0.764	0.63
97_F	186_A	0.762	0.62
258_G	261_S	0.760	0.62
406_I	415_G	0.758	0.62
510_I	517_M	0.757	0.62
259_E	268_K	0.756	0.62
245_A	252_Y	0.755	0.62
470_N	515_P	0.755	0.62
463_D	480_K	0.753	0.62
239_I	361_M	0.753	0.62
454_L	493_A	0.752	0.61
213_V	422_Q	0.752	0.61
140_I	237_P	0.749	0.61
222_E	349_S	0.749	0.61
4_K	151_F	0.747	0.61
84_A	289_G	0.743	0.61
351_V	390_I	0.743	0.61
457_E	509_I	0.741	0.60
199_G	203_L	0.740	0.60
215_V	220_F	0.739	0.60
192_I	195_M	0.739	0.60
7_R	154_N	0.738	0.60
198_S	202_S	0.737	0.60
33_K	52_W	0.736	0.60
179_F	182_M	0.734	0.60
470_N	510_I	0.731	0.59
443_S	463_D	0.730	0.59
305_L	408_K	0.729	0.59
275_G	331_L	0.729	0.59
351_V	355_A	0.725	0.59
275_G	349_S	0.724	0.59
30_T	37_L	0.724	0.59
6_Q	9_G	0.723	0.58
162_P	168_F	0.723	0.58
220_F	346_A	0.720	0.58
290_I	402_F	0.719	0.58
27_G	30_T	0.719	0.58
7_R	467_E	0.718	0.58
468_V	477_V	0.718	0.58
289_G	396_A	0.718	0.58
127_T	136_D	0.717	0.58
242_P	245_A	0.717	0.58
472_A	512_L	0.716	0.58
38_M	48_W	0.716	0.58
278_L	348_M	0.713	0.57
137_T	141_G	0.713	0.57
456_I	465_I	0.713	0.57
259_E	266_P	0.712	0.57
270_L	353_Y	0.709	0.57
454_L	524_I	0.709	0.57
327_E	330_F	0.708	0.57
299_K	412_A	0.708	0.57
469_T	518_R	0.707	0.57
101_V	137_T	0.705	0.57
32_F	38_M	0.703	0.56
297_T	303_K	0.699	0.56
263_S	266_P	0.699	0.56
104_I	187_L	0.698	0.56
491_F	499_V	0.698	0.56
271_F	274_G	0.697	0.56
81_K	523_K	0.695	0.55
302_K	509_I	0.695	0.55
458_A	486_E	0.694	0.55
392_L	442_A	0.693	0.55
83_Q	171_S	0.693	0.55
253_W	256_H	0.691	0.55
291_A	314_T	0.690	0.55
275_G	338_F	0.690	0.55
477_V	518_R	0.688	0.55
417_E	420_E	0.687	0.55
82_A	157_F	0.686	0.54
71_A	142_A	0.685	0.54
453_F	524_I	0.685	0.54
287_I	313_V	0.684	0.54
314_T	318_I	0.684	0.54
466_T	479_V	0.681	0.54
222_E	278_L	0.680	0.54
448_A	516_Q	0.680	0.54
24_I	352_M	0.679	0.54
508_V	517_M	0.677	0.53
26_V	60_W	0.677	0.53
299_K	405_L	0.675	0.53
249_I	253_W	0.674	0.53
256_H	384_Y	0.672	0.53
520_R	524_I	0.672	0.53
68_L	95_L	0.669	0.53
472_A	497_H	0.669	0.53
129_I	135_L	0.668	0.53
465_I	468_V	0.668	0.53
239_I	363_G	0.667	0.52
104_I	190_S	0.666	0.52
126_L	130_A	0.666	0.52
181_I	185_I	0.666	0.52
287_I	398_Y	0.664	0.52
140_I	191_Y	0.663	0.52
347_T	383_T	0.663	0.52
150_V	154_N	0.661	0.52
129_I	133_K	0.661	0.52
3_Q	451_T	0.661	0.52
344_L	404_F	0.657	0.51
57_Q	64_N	0.656	0.51
228_T	331_L	0.655	0.51
483_T	493_A	0.655	0.51
290_I	412_A	0.655	0.51
144_F	217_I	0.655	0.51
286_G	341_H	0.654	0.51
255_Q	260_Y	0.654	0.51
448_A	514_V	0.653	0.51
192_I	196_V	0.651	0.51
404_F	407_L	0.650	0.51
53_Y	57_Q	0.650	0.51
313_V	317_A	0.648	0.50
327_E	341_H	0.648	0.50
3_Q	478_S	0.647	0.50
508_V	514_V	0.646	0.50
421_Q	493_A	0.646	0.50
254_A	261_S	0.645	0.50
206_F	209_A	0.645	0.50
30_T	34_N	0.644	0.50
515_P	522_E	0.643	0.50
290_I	398_Y	0.643	0.50
296_V	400_F	0.642	0.50
475_L	518_R	0.642	0.50
367_E	370_T	0.642	0.50
144_F	189_V	0.640	0.49
111_A	126_L	0.639	0.49
198_S	343_V	0.639	0.49
73_G	88_L	0.638	0.49
94_Y	141_G	0.637	0.49
216_W	346_A	0.637	0.49
304_K	404_F	0.635	0.49
239_I	283_K	0.634	0.49
354_M	457_E	0.632	0.49
169_Q	496_A	0.631	0.48
451_T	454_L	0.631	0.48
455_Y	494_L	0.630	0.48
478_S	504_K	0.630	0.48
462_K	509_I	0.629	0.48
512_L	516_Q	0.628	0.48
237_P	395_T	0.628	0.48
287_I	341_H	0.627	0.48
458_A	470_N	0.626	0.48
491_F	496_A	0.626	0.48
445_A	448_A	0.624	0.48
275_G	345_A	0.621	0.47
516_Q	520_R	0.620	0.47
300_K	304_K	0.620	0.47
163_D	513_S	0.619	0.47
9_G	12_M	0.617	0.47
128_M	133_K	0.615	0.47
334_S	411_I	0.615	0.47
297_T	418_K	0.613	0.47
451_T	455_Y	0.613	0.47
264_A	268_K	0.612	0.46
448_A	520_R	0.612	0.46
408_K	523_K	0.611	0.46
284_I	341_H	0.610	0.46
85_R	518_R	0.610	0.46
221_L	346_A	0.610	0.46
235_Y	345_A	0.608	0.46
135_L	197_Q	0.607	0.46
293_A	406_I	0.607	0.46
451_T	500_V	0.607	0.46
269_E	272_P	0.606	0.46
252_Y	256_H	0.606	0.46
512_L	519_E	0.605	0.46
316_T	329_T	0.605	0.46
448_A	451_T	0.605	0.46
80_K	467_E	0.604	0.46
298_A	416_R	0.604	0.46
156_Y	173_Y	0.602	0.45
178_S	182_M	0.602	0.45
251_T	255_Q	0.601	0.45
139_I	142_A	0.601	0.45
152_L	182_M	0.600	0.45
385_V	505_A	0.600	0.45
448_A	513_S	0.599	0.45
33_K	37_L	0.598	0.45
286_G	401_V	0.598	0.45
16_V	30_T	0.596	0.45
239_I	276_F	0.596	0.45
201_G	205_S	0.596	0.45
2_M	502_N	0.596	0.45
303_K	356_G	0.594	0.44
487_P	490_V	0.594	0.44
352_M	387_Q	0.594	0.44
462_K	525_L	0.593	0.44
322_I	409_F	0.592	0.44
51_C	449_D	0.592	0.44
204_Q	331_L	0.591	0.44
215_V	309_L	0.591	0.44
301_E	420_E	0.591	0.44
31_L	38_M	0.591	0.44
76_V	83_Q	0.590	0.44
307_A	361_M	0.590	0.44
17_L	167_I	0.590	0.44
408_K	440_E	0.590	0.44
334_S	409_F	0.590	0.44
410_N	417_E	0.589	0.44
56_E	60_W	0.587	0.44
513_S	516_Q	0.587	0.44
63_F	322_I	0.586	0.44
188_A	191_Y	0.586	0.44
289_G	368_A	0.586	0.44
406_I	414_P	0.585	0.44
21_F	178_S	0.584	0.43
8_F	157_F	0.583	0.43
31_L	37_L	0.581	0.43
459_L	479_V	0.581	0.43
38_M	52_W	0.580	0.43
477_V	502_N	0.580	0.43
84_A	88_L	0.579	0.43
55_I	379_S	0.578	0.43
81_K	158_D	0.578	0.43
76_V	503_G	0.577	0.43
297_T	411_I	0.576	0.43
97_F	145_I	0.576	0.43
442_A	450_D	0.576	0.43
357_V	389_L	0.575	0.42
504_K	517_M	0.573	0.42
218_Y	304_K	0.573	0.42
485_V	499_V	0.573	0.42
287_I	317_A	0.572	0.42
336_F	411_I	0.572	0.42
142_A	146_S	0.571	0.42
94_Y	140_I	0.569	0.42
273_Q	352_M	0.568	0.42
218_Y	338_F	0.568	0.42
441_T	445_A	0.567	0.42
458_A	477_V	0.567	0.42
299_K	420_E	0.567	0.42
197_Q	271_F	0.566	0.42
284_I	368_A	0.566	0.42
151_F	156_Y	0.565	0.41
362_G	367_E	0.564	0.41
420_E	489_S	0.563	0.41
58_G	100_F	0.562	0.41
251_T	254_A	0.562	0.41
250_V	255_Q	0.561	0.41
310_L	493_A	0.560	0.41
51_C	443_S	0.560	0.41
236_T	242_P	0.560	0.41
357_V	390_I	0.559	0.41
273_Q	276_F	0.558	0.41
160_K	513_S	0.558	0.41
514_V	521_V	0.557	0.41
87_C	90_A	0.557	0.41
17_L	239_I	0.555	0.40
310_L	329_T	0.554	0.40
222_E	342_A	0.554	0.40
508_V	521_V	0.554	0.40
485_V	508_V	0.553	0.40
207_L	238_F	0.553	0.40
473_T	509_I	0.552	0.40
275_G	278_L	0.552	0.40
153_H	171_S	0.552	0.40
33_K	38_M	0.551	0.40
380_H	384_Y	0.551	0.40
500_V	521_V	0.550	0.40
276_F	371_L	0.550	0.40
245_A	249_I	0.548	0.40
446_E	449_D	0.548	0.40
180_F	483_T	0.547	0.40
297_T	399_F	0.547	0.40
98_N	132_I	0.546	0.39
35_K	39_G	0.545	0.39
71_A	228_T	0.545	0.39
224_I	339_A	0.544	0.39
38_M	56_E	0.544	0.39
245_A	250_V	0.544	0.39
454_L	462_K	0.543	0.39
29_S	361_M	0.543	0.39
277_A	283_K	0.543	0.39
223_R	323_T	0.541	0.39
21_F	180_F	0.541	0.39
390_I	394_F	0.541	0.39
466_T	484_K	0.541	0.39
192_I	205_S	0.541	0.39
310_L	413_T	0.541	0.39
494_L	521_V	0.540	0.39
456_I	499_V	0.539	0.39
141_G	228_T	0.539	0.39
456_I	463_D	0.538	0.39
80_K	154_N	0.538	0.39
165_L	177_I	0.537	0.38
301_E	418_K	0.537	0.38
444_A	523_K	0.537	0.38
151_F	483_T	0.537	0.38
77_A	238_F	0.536	0.38
63_F	372_N	0.535	0.38
248_G	251_T	0.534	0.38
253_W	260_Y	0.534	0.38
238_F	272_P	0.533	0.38
101_V	190_S	0.533	0.38
443_S	483_T	0.532	0.38
20_A	223_R	0.531	0.38
356_G	382_M	0.530	0.38
228_T	348_M	0.529	0.38
17_L	331_L	0.528	0.38
265_K	303_K	0.527	0.37
333_I	336_F	0.526	0.37
235_Y	275_G	0.526	0.37
48_W	52_W	0.526	0.37
32_F	35_K	0.526	0.37
346_A	349_S	0.525	0.37
453_F	483_T	0.525	0.37
32_F	52_W	0.525	0.37
272_P	276_F	0.525	0.37
290_I	341_H	0.524	0.37
445_A	449_D	0.524	0.37
250_V	254_A	0.523	0.37
440_E	444_A	0.523	0.37
219_T	345_A	0.522	0.37
236_T	239_I	0.521	0.37
459_L	506_F	0.520	0.37
491_F	512_L	0.520	0.37
156_Y	159_K	0.520	0.37
457_E	484_K	0.519	0.37
398_Y	402_F	0.519	0.37
521_V	525_L	0.519	0.37
60_W	213_V	0.519	0.37
78_L	166_G	0.519	0.37
288_P	291_A	0.517	0.36
83_Q	153_H	0.517	0.36
99_Y	102_S	0.516	0.36
159_K	199_G	0.516	0.36
478_S	482_E	0.515	0.36
443_S	490_V	0.515	0.36
199_G	421_Q	0.515	0.36
343_V	404_F	0.514	0.36
112_F	128_M	0.514	0.36
62_V	96_T	0.514	0.36
95_L	400_F	0.514	0.36
284_I	363_G	0.513	0.36
18_L	256_H	0.512	0.36
287_I	320_A	0.511	0.36
98_N	135_L	0.511	0.36
329_T	339_A	0.510	0.36
340_V	393_S	0.510	0.36
246_E	251_T	0.509	0.36
90_A	501_R	0.509	0.36
92_T	152_L	0.508	0.36
421_Q	442_A	0.508	0.36
514_V	519_E	0.508	0.36
165_L	361_M	0.508	0.36
348_M	352_M	0.507	0.35
380_H	383_T	0.506	0.35
186_A	322_I	0.506	0.35
442_A	447_T	0.506	0.35
182_M	186_A	0.505	0.35
268_K	271_F	0.504	0.35
510_I	513_S	0.504	0.35
63_F	316_T	0.504	0.35
226_I	345_A	0.504	0.35
360_N	363_G	0.503	0.35
79_A	234_I	0.503	0.35
313_V	329_T	0.503	0.35
215_V	221_L	0.502	0.35
184_P	493_A	0.502	0.35
185_I	189_V	0.501	0.35
149_V	177_I	0.501	0.35
73_G	276_F	0.501	0.35
394_F	397_I	0.500	0.35
74_I	143_I	0.500	0.35
127_T	131_G	0.500	0.35

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3qnqA	2	0.7362	100	0.7	Contact Map
1ibaA	1	0.1442	99.9	0.839	Contact Map
3bp3A	1	0.1537	99.9	0.844	Contact Map
3ipjA	1	0.1556	99.9	0.855	Contact Map
4pypA	1	0.6793	42.8	0.977	Contact Map
3wdoA	1	0.7419	28.9	0.979	Contact Map
4ea3A	2	0.1556	28.1	0.979	Contact Map
4jkvA	2	0.1385	27.2	0.979	Contact Map
3w9iA	3	0.2619	23.2	0.98	Contact Map
4mt1A	3	0.2562	15.7	0.981	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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