GREMLIN Database
YHCQ - Spore coat protein F-like protein YhcQ
UniProt: P54601 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 217 (183)
Sequences: 168 (127)
Seq/√Len: 9.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
57_E176_K5.8251.00
50_R63_D4.0740.99
61_I170_I3.3560.95
44_D124_I3.3030.95
72_Q140_L3.1930.94
137_A145_L3.1430.93
138_S142_M3.0510.92
114_V124_I2.9270.90
101_T171_F2.8660.89
154_R165_E2.4760.81
137_A141_T2.4230.79
35_V156_L2.1540.70
71_S88_Q2.1000.68
37_S127_R2.0860.68
133_I170_I2.0130.65
69_I163_Y1.9660.63
26_G30_F1.9610.63
26_G105_M1.9500.62
61_I65_Q1.9280.61
157_S165_E1.9180.61
136_Q163_Y1.8950.60
157_S164_V1.8880.60
48_M120_I1.8860.60
69_I136_Q1.8030.56
75_I88_Q1.7850.55
41_T128_Q1.7750.55
85_E89_K1.7700.54
107_P189_D1.7580.54
42_V69_I1.7310.53
39_T72_Q1.6300.48
62_L130_L1.6260.48
124_I128_Q1.6250.48
65_Q116_S1.6040.47
159_Q200_A1.5800.46
60_N96_K1.5100.43
27_H31_D1.5060.43
49_L128_Q1.4880.42
175_N182_V1.4550.41
28_E178_G1.4420.40
26_G189_D1.4410.40
158_A161_Q1.4370.40
32_M41_T1.4180.39
70_T125_I1.4090.39
139_M200_A1.3890.38
54_K59_L1.3880.38
140_L163_Y1.3710.37
163_Y166_M1.3540.36
46_F129_M1.3430.36
104_G175_N1.3390.36
36_L183_P1.3350.36
179_Y197_F1.3280.35
178_G192_Q1.3010.34
46_F69_I1.2970.34
77_A193_L1.2910.34
56_Q117_M1.2790.33
42_V56_Q1.2620.33
125_I163_Y1.2460.32
127_R131_C1.2450.32
49_L76_T1.2390.32
52_F125_I1.2200.31
125_I170_I1.2020.30
54_K122_D1.1970.30
44_D72_Q1.1720.29
132_A135_A1.1720.29
72_Q163_Y1.1710.29
141_T145_L1.1530.29
65_Q87_S1.1360.28
32_M152_V1.1160.27
41_T170_I1.1120.27
178_G186_D1.1060.27
178_G204_M1.0970.27
74_N200_A1.0960.27
71_S87_S1.0890.26
175_N181_Q1.0750.26
131_C135_A1.0670.26
55_D177_H1.0650.26
66_H127_R1.0630.25
95_M158_A1.0470.25
73_Y113_P1.0430.25
44_D48_M1.0350.25
41_T127_R1.0170.24
165_E169_E1.0120.24
53_C59_L1.0070.24
148_T184_Q1.0070.24
71_S75_I0.9980.23
35_V141_T0.9920.23
62_L119_D0.9900.23
124_I127_R0.9890.23
44_D114_V0.9870.23
105_M192_Q0.9860.23
44_D171_F0.9750.23
28_E73_Y0.9640.22
56_Q60_N0.9620.22
146_E180_Y0.9610.22
108_S178_G0.9510.22
59_L201_Q0.9480.22
22_K125_I0.9340.21
104_G108_S0.9270.21
42_V128_Q0.9220.21
90_T185_L0.9140.21
67_Q160_I0.9110.21
118_N122_D0.9110.21
26_G197_F0.9070.21
122_D125_I0.9060.21
43_L136_Q0.9050.20
79_C189_D0.9030.20
172_L178_G0.9010.20
50_R59_L0.8930.20
89_K159_Q0.8850.20
59_L71_S0.8780.20
87_S203_Q0.8660.19
146_E167_A0.8660.19
40_L129_M0.8600.19
71_S89_K0.8580.19
105_M175_N0.8510.19
83_G95_M0.8490.19
105_M190_M0.8480.19
41_T49_L0.8470.19
55_D58_L0.8460.19
80_F189_D0.8460.19
44_D121_D0.8400.19
147_M156_L0.8380.19
59_L63_D0.8350.19
68_F162_E0.8340.19
46_F197_F0.8330.18
137_A162_E0.8330.18
105_M181_Q0.8260.18
125_I167_A0.8230.18
51_Q77_A0.8180.18
59_L77_A0.8180.18
114_V193_L0.8150.18
144_S159_Q0.8120.18
44_D140_L0.8070.18
32_M36_L0.8030.18
31_D179_Y0.8020.18
189_D192_Q0.7950.17
65_Q163_Y0.7930.17
42_V132_A0.7910.17
91_A201_Q0.7840.17
197_F201_Q0.7830.17
60_N190_M0.7830.17
86_P189_D0.7760.17
177_H198_A0.7750.17
73_Y180_Y0.7720.17
184_Q189_D0.7710.17
134_K153_R0.7690.17
118_N131_C0.7690.17
132_A136_Q0.7620.17
25_G169_E0.7540.16
120_I202_G0.7530.16
22_K47_M0.7480.16
173_Y183_P0.7430.16
48_M125_I0.7400.16
43_L121_D0.7390.16
107_P187_A0.7390.16
27_H198_A0.7360.16
162_E173_Y0.7330.16
89_K92_T0.7250.16
38_G139_M0.7240.16
72_Q133_I0.7240.16
54_K92_T0.7220.16
23_N80_F0.7210.16
164_V168_F0.7210.16
100_Q178_G0.7190.16
50_R116_S0.7160.16
23_N65_Q0.7130.15
75_I204_M0.7110.15
141_T197_F0.7110.15
25_G182_V0.6990.15
63_D116_S0.6970.15
152_V167_A0.6970.15
41_T133_I0.6960.15
39_T67_Q0.6950.15
73_Y167_A0.6910.15
58_L126_S0.6880.15
82_T172_L0.6850.15
47_M114_V0.6840.15
23_N154_R0.6830.15
85_E164_V0.6820.15
50_R131_C0.6810.15
35_V145_L0.6810.15
133_I163_Y0.6760.15
163_Y171_F0.6760.15
61_I96_K0.6750.15
47_M117_M0.6740.15
201_Q204_M0.6720.15
37_S155_V0.6700.15
42_V136_Q0.6700.15
149_N168_F0.6690.15
104_G183_P0.6680.14
149_N175_N0.6660.14
53_C125_I0.6620.14
48_M119_D0.6570.14
48_M99_N0.6520.14
92_T158_A0.6470.14
121_D124_I0.6460.14
154_R157_S0.6380.14
85_E92_T0.6370.14
121_D204_M0.6330.14
139_M142_M0.6330.14
27_H33_H0.6320.14
132_A167_A0.6310.14
44_D128_Q0.6240.14
36_L116_S0.6220.13
175_N183_P0.6220.13
55_D173_Y0.6170.13
41_T132_A0.6160.13
29_M81_K0.6140.13
27_H113_P0.6130.13
41_T124_I0.6130.13
187_A196_S0.6130.13
32_M156_L0.6120.13
39_T69_I0.6120.13
161_Q165_E0.6110.13
39_T140_L0.6100.13
75_I86_P0.6060.13
35_V76_T0.6050.13
197_F204_M0.6010.13
50_R65_Q0.6000.13
120_I128_Q0.5990.13
54_K194_R0.5990.13
79_C155_V0.5970.13
53_C188_Q0.5930.13
56_Q155_V0.5920.13
135_A157_S0.5890.13
154_R169_E0.5880.13
73_Y146_E0.5870.13
86_P152_V0.5840.13
49_L98_D0.5830.13
41_T117_M0.5800.13
32_M143_A0.5770.13
25_G175_N0.5730.13
36_L152_V0.5730.13
152_V169_E0.5730.13
38_G138_S0.5720.12
41_T152_V0.5720.12
95_M109_Q0.5710.12
103_Y175_N0.5690.12
100_Q171_F0.5630.12
52_F127_R0.5620.12
72_Q171_F0.5590.12
126_S174_Q0.5580.12
53_C167_A0.5570.12
28_E113_P0.5540.12
93_Y165_E0.5530.12
157_S161_Q0.5510.12
47_M127_R0.5510.12
47_M186_D0.5490.12
101_T104_G0.5470.12
105_M108_S0.5450.12
102_V116_S0.5430.12
101_T172_L0.5400.12
126_S172_L0.5390.12
40_L53_C0.5390.12
39_T202_G0.5390.12
76_T164_V0.5360.12
120_I160_I0.5330.12
49_L124_I0.5280.12
32_M163_Y0.5270.12
36_L80_F0.5260.12
100_Q201_Q0.5250.12
125_I133_I0.5220.12
78_E87_S0.5210.12
59_L102_V0.5130.11
43_L66_H0.5090.11
30_F136_Q0.5090.11
108_S189_D0.5080.11
64_R97_E0.5080.11
108_S167_A0.5070.11
41_T139_M0.5070.11
47_M131_C0.5030.11
38_G136_Q0.5020.11
28_E180_Y0.5010.11
60_N108_S0.5000.11
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2rbdA 4 0.7281 100 0.66 Contact Map
4etrA 1 0.553 94.6 0.929 Contact Map
1vjxA 1 0.6498 72.7 0.949 Contact Map
2oh3A 2 0.6406 63.5 0.953 Contact Map
4am5A 6 0.6774 53.8 0.955 Contact Map
4tofA 6 0.6682 43.9 0.958 Contact Map
1jgcA 6 0.682 38 0.959 Contact Map
2fzfA 2 0.6912 31.4 0.961 Contact Map
1n1qA 6 0.6452 30.3 0.961 Contact Map
3uoiA 7 0.6682 29.9 0.961 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0072 seconds.