TCYP - BACSU - GREMLIN Contacts

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TCYP - L-cystine uptake protein TcyP

UniProt:	P54596	Sequences: METLLVVLHVFILFLLILGLFVMQKKHVSFSKRVFTALGLGIVFGFALQLIYGPTSNIVIQTADWFNIAGGGYVKLLQMVVMPLVFISILGAFTKLKLTKNLGKISGLIIGILVATTAVAAAVGIASALSFDLQAIQVDQGSTELSRGQELQQKSEDMTAKTLPQQIVELLPGNPFLDFTGARPTSTIAVVIFAAFLGVAFLGVKHKQPEQAETFKKLVDAVYAIVMRVVTLILRLTPYGVLAIMTKTIATSDLDSILKLGMFVIASYAALITMFIIHLLLLTFSGLNPVIYLKKAVPVLVFAFTSRSSAGALPLNIKTQRSMGVPEGIANFAGSFGLSIGQNGCAGIYPAMLAMMIAPTVGQNPFDPVFIITVIAVVAISSFGVAGVGGGATFAALLVLSSLNMPVALAGLLISIEPLIDMGRTALNVSGSMTSGLITSKVTKEIDQGAFHDQSRVIEAEEA	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	463 (395)
Sequences:	6272 (3786)
Seq/√Len:	190.5

ECOLI - YDJN GLTP DCTA SSTT
BACSU - TCYP GLTT DCTA GLTP
HALSA - Q9HHN5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
177_L	181_G	4.770	1.00
213_E	217_K	3.685	1.00
210_E	213_E	3.215	1.00
129_L	371_I	3.137	1.00
170_L	192_I	3.085	1.00
127_S	270_A	3.055	1.00
108_L	443_T	3.008	1.00
86_F	194_A	2.904	1.00
67_N	71_G	2.785	1.00
90_L	219_V	2.737	1.00
318_K	321_R	2.731	1.00
44_F	242_L	2.666	1.00
313_L	334_G	2.641	1.00
72_G	171_L	2.584	1.00
214_T	221_A	2.582	1.00
326_P	445_E	2.514	1.00
132_D	135_A	2.513	1.00
367_D	370_F	2.505	1.00
86_F	90_L	2.500	1.00
69_A	243_A	2.474	1.00
321_R	327_E	2.464	1.00
228_R	231_T	2.446	1.00
87_I	222_V	2.441	1.00
441_K	448_Q	2.421	1.00
48_L	242_L	2.332	1.00
37_A	235_R	2.308	1.00
268_Y	423_G	2.242	1.00
197_L	225_I	2.241	1.00
326_P	440_S	2.236	1.00
300_L	430_S	2.222	1.00
47_A	51_I	2.196	1.00
112_I	435_S	2.128	1.00
205_K	212_A	2.101	1.00
116_T	281_L	2.078	1.00
265_I	269_A	2.060	1.00
108_L	442_V	2.009	1.00
211_Q	224_A	2.009	1.00
34_V	49_Q	2.005	1.00
165_Q	169_E	2.005	1.00
299_V	319_T	2.001	1.00
33_R	36_T	1.991	1.00
173_G	177_L	1.973	1.00
215_F	218_L	1.947	1.00
364_N	367_D	1.940	1.00
34_V	37_A	1.887	1.00
131_F	266_A	1.873	1.00
127_S	272_I	1.873	1.00
357_I	409_L	1.869	1.00
37_A	49_Q	1.863	1.00
80_V	233_I	1.847	1.00
214_T	217_K	1.846	1.00
126_A	130_S	1.845	1.00
122_A	126_A	1.835	1.00
87_I	226_V	1.829	1.00
271_L	423_G	1.822	1.00
325_V	437_L	1.821	1.00
133_L	359_P	1.789	1.00
95_K	220_D	1.774	1.00
128_A	355_M	1.773	1.00
107_G	111_G	1.756	1.00
318_K	322_S	1.756	1.00
215_F	221_A	1.751	1.00
186_S	189_A	1.747	1.00
417_E	424_R	1.723	1.00
282_L	434_T	1.706	1.00
203_G	228_R	1.699	1.00
39_G	43_V	1.695	1.00
333_A	436_G	1.688	1.00
34_V	38_L	1.674	1.00
175_P	193_F	1.664	1.00
215_F	225_I	1.659	1.00
131_F	269_A	1.641	1.00
201_F	225_I	1.639	1.00
176_F	180_T	1.631	1.00
104_K	443_T	1.610	1.00
258_L	262_M	1.606	1.00
181_G	186_S	1.601	1.00
325_V	440_S	1.586	1.00
316_N	433_M	1.582	1.00
176_F	179_F	1.576	1.00
296_A	433_M	1.574	1.00
295_K	323_M	1.573	1.00
127_S	266_A	1.567	1.00
41_G	45_G	1.560	1.00
128_A	352_M	1.555	1.00
364_N	369_V	1.550	1.00
285_S	441_K	1.546	1.00
86_F	179_F	1.531	1.00
41_G	242_L	1.528	1.00
33_R	37_A	1.520	1.00
32_K	36_T	1.515	1.00
38_L	49_Q	1.481	1.00
72_G	168_V	1.477	1.00
421_D	425_T	1.474	1.00
291_I	294_K	1.474	1.00
271_L	427_L	1.470	1.00
94_T	216_K	1.463	1.00
361_V	409_L	1.456	1.00
357_I	405_M	1.444	1.00
78_Q	173_G	1.439	1.00
270_A	348_I	1.435	1.00
295_K	322_S	1.428	1.00
200_A	229_V	1.427	1.00
300_L	426_A	1.418	1.00
218_L	221_A	1.404	1.00
71_G	75_K	1.393	1.00
203_G	232_L	1.388	1.00
317_I	330_A	1.381	1.00
48_L	52_Y	1.374	1.00
310_A	387_G	1.367	1.00
261_G	265_I	1.357	1.00
79_M	193_F	1.342	1.00
85_V	187_T	1.340	1.00
290_V	294_K	1.338	1.00
36_T	40_L	1.336	1.00
220_D	224_A	1.330	1.00
326_P	329_I	1.325	1.00
125_I	371_I	1.307	1.00
281_L	438_I	1.306	1.00
169_E	186_S	1.306	1.00
109_I	333_A	1.298	1.00
139_D	362_G	1.297	1.00
93_F	195_A	1.289	1.00
204_V	212_A	1.280	1.00
91_G	219_V	1.260	1.00
329_I	440_S	1.259	1.00
201_F	215_F	1.254	1.00
283_T	286_G	1.254	1.00
368_P	372_I	1.253	1.00
282_L	287_L	1.252	1.00
75_K	173_G	1.251	1.00
171_L	192_I	1.247	1.00
32_K	40_L	1.238	1.00
272_I	276_I	1.235	1.00
339_S	342_Q	1.225	1.00
214_T	218_L	1.223	1.00
296_A	430_S	1.221	1.00
197_L	222_V	1.219	1.00
288_N	291_I	1.218	1.00
440_S	446_I	1.218	1.00
37_A	41_G	1.208	1.00
316_N	334_G	1.197	1.00
274_M	427_L	1.192	1.00
364_N	370_F	1.190	1.00
35_F	49_Q	1.189	1.00
266_A	352_M	1.188	1.00
440_S	444_K	1.175	1.00
258_L	261_G	1.171	1.00
82_M	190_V	1.171	1.00
196_F	229_V	1.169	1.00
175_P	180_T	1.167	1.00
80_V	230_V	1.167	1.00
264_V	416_I	1.166	1.00
200_A	232_L	1.159	1.00
231_T	318_K	1.158	1.00
162_T	165_Q	1.154	1.00
273_T	277_I	1.154	1.00
232_L	236_L	1.153	1.00
35_F	38_L	1.149	1.00
101_N	328_G	1.141	1.00
280_L	283_T	1.139	1.00
247_K	251_T	1.136	1.00
393_T	414_I	1.136	1.00
111_G	115_A	1.134	1.00
262_M	265_I	1.132	1.00
259_K	262_M	1.129	1.00
374_V	403_L	1.122	1.00
303_A	425_T	1.120	1.00
122_A	375_I	1.112	1.00
276_I	280_L	1.111	1.00
44_F	48_L	1.111	1.00
349_Y	417_E	1.099	1.00
226_V	230_V	1.098	1.00
205_K	213_E	1.095	1.00
354_A	374_V	1.094	1.00
343_N	382_S	1.094	1.00
313_L	338_L	1.092	1.00
292_Y	296_A	1.091	1.00
204_V	221_A	1.090	1.00
67_N	247_K	1.089	1.00
126_A	129_L	1.083	1.00
43_V	47_A	1.080	1.00
264_V	419_L	1.074	1.00
312_A	316_N	1.071	1.00
53_G	250_A	1.070	1.00
174_N	178_D	1.067	1.00
279_L	293_L	1.065	1.00
113_L	333_A	1.065	1.00
104_K	108_L	1.057	1.00
195_A	199_V	1.055	1.00
204_V	225_I	1.049	1.00
217_K	221_A	1.047	1.00
87_I	91_G	1.047	1.00
69_A	236_L	1.044	1.00
72_G	76_L	1.043	1.00
215_F	219_V	1.035	1.00
316_N	429_V	1.035	1.00
134_Q	359_P	1.034	1.00
440_S	445_E	1.032	1.00
320_Q	327_E	1.030	1.00
32_K	37_A	1.025	1.00
298_P	322_S	1.023	1.00
116_T	343_N	1.022	1.00
122_A	372_I	1.010	1.00
177_L	180_T	1.010	1.00
372_I	376_A	1.010	1.00
345_C	392_A	1.003	1.00
287_L	446_I	1.002	1.00
255_D	258_L	1.001	1.00
286_G	441_K	0.998	0.99
307_R	418_P	0.998	0.99
349_Y	424_R	0.994	0.99
320_Q	330_A	0.994	0.99
115_A	119_V	0.989	0.99
213_E	216_K	0.989	0.99
441_K	444_K	0.987	0.99
47_A	50_L	0.985	0.99
276_I	279_L	0.983	0.99
105_I	329_I	0.976	0.99
236_L	239_Y	0.972	0.99
217_K	220_D	0.967	0.99
124_G	351_A	0.964	0.99
52_Y	55_T	0.955	0.99
127_S	131_F	0.948	0.99
287_L	291_I	0.944	0.99
325_V	330_A	0.937	0.99
31_S	37_A	0.929	0.99
49_Q	53_G	0.926	0.99
294_K	297_V	0.922	0.99
260_L	263_F	0.921	0.99
267_S	352_M	0.920	0.99
41_G	49_Q	0.917	0.99
212_A	221_A	0.915	0.99
70_G	244_I	0.914	0.99
38_L	42_I	0.910	0.99
228_R	232_L	0.909	0.99
175_P	178_D	0.909	0.99
164_P	168_V	0.907	0.99
212_A	216_K	0.906	0.99
368_P	371_I	0.903	0.99
54_P	64_D	0.898	0.99
89_I	191_V	0.896	0.99
295_K	319_T	0.896	0.99
98_L	101_N	0.893	0.99
341_G	432_S	0.892	0.99
196_F	232_L	0.892	0.99
389_G	421_D	0.890	0.99
158_M	161_K	0.887	0.99
355_M	371_I	0.884	0.99
319_T	322_S	0.884	0.99
312_A	315_L	0.880	0.99
55_T	65_W	0.878	0.99
309_S	428_N	0.876	0.99
381_S	399_V	0.875	0.99
304_F	422_M	0.872	0.99
350_P	396_A	0.871	0.99
192_I	196_F	0.870	0.99
295_K	299_V	0.868	0.99
299_V	312_A	0.867	0.99
199_V	203_G	0.866	0.99
299_V	316_N	0.865	0.99
267_S	420_I	0.863	0.99
114_V	118_A	0.859	0.98
205_K	216_K	0.854	0.98
125_I	129_L	0.852	0.98
80_V	229_V	0.848	0.98
35_F	42_I	0.847	0.98
178_D	193_F	0.846	0.98
75_K	78_Q	0.845	0.98
246_T	250_A	0.844	0.98
273_T	279_L	0.843	0.98
167_I	171_L	0.842	0.98
90_L	201_F	0.840	0.98
118_A	122_A	0.837	0.98
349_Y	420_I	0.836	0.98
242_L	246_T	0.835	0.98
142_S	145_L	0.834	0.98
52_Y	66_F	0.834	0.98
161_K	165_Q	0.832	0.98
91_G	220_D	0.830	0.98
194_A	198_G	0.828	0.98
262_M	359_P	0.825	0.98
33_R	38_L	0.824	0.98
297_V	301_V	0.822	0.98
168_V	171_L	0.820	0.98
66_F	246_T	0.819	0.98
87_I	219_V	0.817	0.98
342_Q	432_S	0.816	0.98
201_F	219_V	0.815	0.98
275_F	279_L	0.814	0.98
264_V	420_I	0.809	0.98
65_W	68_I	0.805	0.98
179_F	193_F	0.804	0.98
292_Y	433_M	0.804	0.98
31_S	36_T	0.799	0.98
165_Q	168_V	0.797	0.98
218_L	222_V	0.797	0.98
366_F	370_F	0.794	0.97
397_L	410_A	0.792	0.97
231_T	235_R	0.790	0.97
141_G	144_E	0.788	0.97
354_A	399_V	0.787	0.97
278_H	282_L	0.787	0.97
96_L	105_I	0.787	0.97
353_L	413_L	0.785	0.97
105_I	439_T	0.783	0.97
302_F	315_L	0.780	0.97
338_L	432_S	0.778	0.97
302_F	312_A	0.778	0.97
66_F	243_A	0.777	0.97
269_A	272_I	0.776	0.97
70_G	240_G	0.771	0.97
197_L	229_V	0.769	0.97
263_F	413_L	0.769	0.97
63_A	250_A	0.769	0.97
263_F	271_L	0.768	0.97
223_Y	227_M	0.767	0.97
65_W	69_A	0.764	0.97
90_L	194_A	0.764	0.97
163_L	167_I	0.762	0.97
132_D	359_P	0.762	0.97
393_T	410_A	0.762	0.97
226_V	233_I	0.760	0.97
99_T	199_V	0.756	0.97
71_G	168_V	0.753	0.97
73_Y	237_T	0.751	0.96
329_I	333_A	0.748	0.96
76_L	171_L	0.747	0.96
237_T	240_G	0.743	0.96
42_I	245_M	0.741	0.96
266_A	269_A	0.741	0.96
303_A	429_V	0.740	0.96
161_K	169_E	0.740	0.96
267_S	271_L	0.739	0.96
171_L	174_N	0.737	0.96
340_I	383_F	0.737	0.96
88_S	223_Y	0.736	0.96
350_P	393_T	0.736	0.96
178_D	181_G	0.736	0.96
100_K	103_G	0.735	0.96
174_N	193_F	0.735	0.96
33_R	49_Q	0.734	0.96
369_V	372_I	0.732	0.96
193_F	197_L	0.731	0.96
101_N	104_K	0.728	0.96
90_L	197_L	0.724	0.96
307_R	421_D	0.724	0.96
40_L	44_F	0.722	0.96
361_V	408_A	0.720	0.96
264_V	268_Y	0.717	0.95
441_K	446_I	0.716	0.95
291_I	295_K	0.715	0.95
287_L	295_K	0.715	0.95
94_T	202_L	0.711	0.95
139_D	142_S	0.711	0.95
127_S	269_A	0.710	0.95
282_L	285_S	0.709	0.95
48_L	51_I	0.708	0.95
299_V	315_L	0.704	0.95
440_S	447_D	0.703	0.95
155_S	158_M	0.700	0.95
49_Q	52_Y	0.699	0.95
263_F	420_I	0.698	0.95
73_Y	236_L	0.696	0.95
262_M	266_A	0.695	0.95
397_L	401_S	0.694	0.95
192_I	236_L	0.694	0.95
204_V	224_A	0.691	0.94
141_G	145_L	0.690	0.94
124_G	352_M	0.690	0.94
118_A	379_A	0.689	0.94
270_A	352_M	0.688	0.94
345_C	385_V	0.687	0.94
393_T	420_I	0.686	0.94
406_P	409_L	0.683	0.94
179_F	189_A	0.681	0.94
119_V	277_I	0.681	0.94
371_I	375_I	0.676	0.94
263_F	349_Y	0.676	0.94
274_M	279_L	0.675	0.94
210_E	217_K	0.675	0.94
174_N	177_L	0.674	0.94
64_D	250_A	0.674	0.94
38_L	44_F	0.673	0.94
345_C	350_P	0.673	0.94
316_N	432_S	0.672	0.94
90_L	222_V	0.671	0.93
48_L	66_F	0.671	0.93
34_V	40_L	0.670	0.93
31_S	34_V	0.670	0.93
224_A	228_R	0.668	0.93
111_G	114_V	0.668	0.93
327_E	331_N	0.662	0.93
129_L	368_P	0.661	0.93
292_Y	437_L	0.660	0.93
302_F	306_S	0.660	0.93
123_V	277_I	0.658	0.93
38_L	41_G	0.658	0.93
48_L	53_G	0.658	0.93
42_I	53_G	0.655	0.93
75_K	169_E	0.655	0.93
354_A	358_A	0.654	0.93
336_F	340_I	0.654	0.93
42_I	49_Q	0.652	0.93
168_V	172_P	0.649	0.92
385_V	395_A	0.648	0.92
181_G	185_T	0.647	0.92
124_G	348_I	0.642	0.92
350_P	385_V	0.642	0.92
445_E	448_Q	0.640	0.92
221_A	225_I	0.640	0.92
373_T	403_L	0.639	0.92
154_K	157_D	0.639	0.92
48_L	55_T	0.637	0.92
76_L	196_F	0.637	0.92
46_F	49_Q	0.636	0.92
97_K	100_K	0.636	0.92
123_V	272_I	0.636	0.92
98_L	106_S	0.635	0.92
109_I	439_T	0.635	0.92
338_L	342_Q	0.635	0.92
275_F	280_L	0.634	0.91
358_A	363_Q	0.630	0.91
263_F	352_M	0.630	0.91
320_Q	331_N	0.627	0.91
282_L	438_I	0.626	0.91
228_R	235_R	0.625	0.91
230_V	304_F	0.625	0.91
123_V	270_A	0.624	0.91
213_E	218_L	0.623	0.91
179_F	190_V	0.623	0.91
241_V	389_G	0.622	0.91
369_V	373_T	0.620	0.91
197_L	215_F	0.620	0.91
407_V	410_A	0.618	0.90
375_I	378_V	0.615	0.90
237_T	306_S	0.614	0.90
211_Q	217_K	0.613	0.90
354_A	357_I	0.613	0.90
101_N	445_E	0.613	0.90
34_V	41_G	0.613	0.90
212_A	225_I	0.611	0.90
48_L	246_T	0.611	0.90
174_N	180_T	0.610	0.90
383_F	432_S	0.609	0.90
409_L	412_L	0.608	0.90
120_A	348_I	0.607	0.90
31_S	49_Q	0.606	0.90
166_Q	169_E	0.606	0.90
172_P	178_D	0.606	0.90
131_F	262_M	0.603	0.89
201_F	216_K	0.603	0.89
113_L	435_S	0.603	0.89
134_Q	137_Q	0.602	0.89
378_V	395_A	0.600	0.89
334_G	436_G	0.600	0.89
366_F	374_V	0.599	0.89
84_L	191_V	0.599	0.89
287_L	447_D	0.599	0.89
119_V	123_V	0.599	0.89
91_G	216_K	0.599	0.89
278_H	431_G	0.596	0.89
240_G	244_I	0.596	0.89
178_D	185_T	0.595	0.89
220_D	223_Y	0.595	0.89
172_P	175_P	0.592	0.88
385_V	392_A	0.591	0.88
35_F	39_G	0.589	0.88
387_G	390_G	0.588	0.88
114_V	383_F	0.586	0.88
277_I	280_L	0.584	0.88
156_E	159_T	0.584	0.88
239_Y	243_A	0.584	0.88
436_G	440_S	0.583	0.88
274_M	278_H	0.581	0.87
37_A	42_I	0.580	0.87
361_V	406_P	0.580	0.87
284_F	438_I	0.580	0.87
324_G	447_D	0.579	0.87
129_L	355_M	0.579	0.87
221_A	224_A	0.577	0.87
215_F	222_V	0.576	0.87
326_P	330_A	0.575	0.87
353_L	417_E	0.575	0.87
119_V	122_A	0.574	0.87
172_P	176_F	0.574	0.87
40_L	49_Q	0.573	0.87
116_T	120_A	0.573	0.87
72_G	192_I	0.572	0.87
54_P	250_A	0.572	0.87
292_Y	323_M	0.569	0.86
260_L	264_V	0.568	0.86
101_N	106_S	0.568	0.86
104_K	107_G	0.567	0.86
91_G	95_K	0.567	0.86
350_P	354_A	0.566	0.86
124_G	349_Y	0.565	0.86
216_K	220_D	0.562	0.86
310_A	338_L	0.562	0.86
79_M	229_V	0.560	0.86
351_A	378_V	0.560	0.86
296_A	316_N	0.559	0.85
53_G	63_A	0.558	0.85
191_V	361_V	0.557	0.85
175_P	179_F	0.557	0.85
204_V	228_R	0.557	0.85
357_I	395_A	0.556	0.85
364_N	368_P	0.556	0.85
329_I	445_E	0.556	0.85
81_V	391_G	0.556	0.85
127_S	265_I	0.555	0.85
123_V	273_T	0.554	0.85
281_L	284_F	0.554	0.85
113_L	432_S	0.553	0.85
377_V	402_S	0.553	0.85
345_C	424_R	0.553	0.85
127_S	130_S	0.552	0.85
205_K	211_Q	0.551	0.85
45_G	246_T	0.550	0.85
392_A	399_V	0.548	0.84
315_L	318_K	0.548	0.84
125_I	375_I	0.547	0.84
263_F	353_L	0.547	0.84
382_S	394_F	0.546	0.84
173_G	181_G	0.546	0.84
343_N	431_G	0.544	0.84
76_L	233_I	0.543	0.84
294_K	298_P	0.541	0.84
117_T	346_A	0.541	0.84
186_S	190_V	0.541	0.84
323_M	437_L	0.540	0.83
387_G	391_G	0.540	0.83
139_D	143_T	0.539	0.83
390_G	394_F	0.539	0.83
39_G	49_Q	0.538	0.83
312_A	338_L	0.538	0.83
342_Q	385_V	0.538	0.83
39_G	42_I	0.536	0.83
430_S	434_T	0.534	0.83
444_K	449_G	0.534	0.83
258_L	264_V	0.534	0.83
44_F	49_Q	0.533	0.83
317_I	334_G	0.533	0.83
307_R	311_G	0.533	0.83
213_E	221_A	0.532	0.83
167_I	175_P	0.532	0.83
76_L	236_L	0.531	0.82
31_S	38_L	0.530	0.82
159_T	162_T	0.527	0.82
34_V	53_G	0.526	0.82
107_G	110_I	0.526	0.82
38_L	237_T	0.525	0.82
283_T	288_N	0.524	0.82
52_Y	246_T	0.523	0.81
37_A	40_L	0.523	0.81
113_L	273_T	0.523	0.81
312_A	429_V	0.522	0.81
265_I	268_Y	0.521	0.81
320_Q	334_G	0.521	0.81
326_P	444_K	0.520	0.81
320_Q	433_M	0.520	0.81
48_L	63_A	0.520	0.81
96_L	436_G	0.518	0.81
51_I	55_T	0.517	0.81
121_A	379_A	0.517	0.81
321_R	330_A	0.517	0.81
428_N	432_S	0.517	0.81
72_G	236_L	0.516	0.81
345_C	421_D	0.516	0.81
235_R	239_Y	0.515	0.80
397_L	407_V	0.512	0.80
200_A	204_V	0.512	0.80
303_A	426_A	0.512	0.80
157_D	160_A	0.511	0.80
392_A	396_A	0.510	0.80
253_D	257_I	0.510	0.80
325_V	436_G	0.509	0.80
84_L	226_V	0.507	0.79
444_K	448_Q	0.507	0.79
42_I	241_V	0.507	0.79
81_V	412_L	0.506	0.79
375_I	379_A	0.504	0.79
175_P	185_T	0.504	0.79
116_T	340_I	0.504	0.79
296_A	300_L	0.503	0.79
337_G	436_G	0.503	0.79
113_L	337_G	0.503	0.79
77_L	302_F	0.502	0.79
200_A	225_I	0.502	0.79
292_Y	434_T	0.501	0.79
173_G	178_D	0.500	0.79
154_K	158_M	0.500	0.79

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2nwlA	3	0.8488	100	0.14	Contact Map
4bgnA	3	0.4233	10.7	0.974	Contact Map
3zuxA	1	0.378	6.9	0.976	Contact Map
2m8rA	1	0.1145	5.9	0.977	Contact Map
4n7wA	2	0.3866	5.6	0.977	Contact Map
3nd0A	2	0.8121	4.9	0.978	Contact Map
1ji6A	1	0.1922	4.1	0.979	Contact Map
2cfqA	1	0.3715	3.6	0.979	Contact Map
4cz8A	2	0.5767	3.2	0.98	Contact Map
4wl1A	3	0.0648	2.7	0.981	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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