MCPC - BACSU - GREMLIN Contacts

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MCPC - Methyl-accepting chemotaxis protein McpC

UniProt:	P54576	Sequences: MFKKLHMKIAVFVSIMLIITVVLLMLSSYLTLKPMITEDGKNTTQNVTQSLEQNIELQLKSYAISLSRLANGELTHTFVTKPSKEASRLFHDDIKQIKDNDDYVAMAYIGTAKKEMFTYPKADFAEDYDPTSRPWYKLAAETPDQVVWTEPYKDVVTGDMIVTASKAILDRQKVIGVASYDLKLSAIQSMVNKQKVPYKGFAFLADASGNLLAHPSNQGKNISKDQTLQTIASEKKGIQDVNGKMVVYQTIGETGWKVGTQFDTDQLMWISDKMNRANLWISLIALIITIILSYFLAKTITGPIQQLIVKTKAVSAGDLTVRAESKSKDEVGILTRDFNLMVENMKEMVEQVRLSSGKVSDTSEQLTAVAAETNETSGQIAKAIEEVAAGASEQASEVETINEKSESLSTKIRQIAEEAGGIKERSKSSEDASYKGLDALGQLLMKSNEANMETKKVETMLLDLENQTKNIEEVVTAISNISDQTNLLALNASIEAARAGESGRGFAVVADEVRKLAEQSALSTKHISETVKLIQLETKEASHAMVEASRMNDEQNSAIHETGEVLNTITAEMQSLVQGIDHIYAEIQRMSEEQLAISEAIQSISAISQESAAAAEEVNASTDEQLVTLDKVKHSTETLKHASQELMNTIAKFTL	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	655 (614)
Sequences:	7179 (6173)
Seq/√Len:	249.1

ECOLI - AER MCP3 MCP1 MCP4 MCP2
BACSU - MCPC MCPB TLPA TLPB MCPA YVAQ YOAH TLPC
HALSA - HTR4 COST Q9HRA1 HTR2 Q9HR88 Q9HRN6 Q9HP10 Q9HQX8 HTR7 Q9HS86 Q9HPA2 Q9HPQ5 HTR9 HMAT HTR1 Q9HQT5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
327_S	332_G	6.048	1.00
322_R	346_K	3.931	1.00
8_K	329_D	3.678	1.00
6_H	298_K	3.418	1.00
26_L	30_L	3.380	1.00
140_A	174_V	3.364	1.00
329_D	332_G	3.236	1.00
313_A	318_D	3.129	1.00
199_K	266_Q	2.903	1.00
170_D	173_K	2.811	1.00
311_T	341_M	2.629	1.00
108_Y	179_S	2.571	1.00
312_K	333_I	2.562	1.00
463_D	537_E	2.493	1.00
390_G	607_I	2.457	1.00
450_A	555_Q	2.416	1.00
297_A	301_T	2.405	1.00
466_N	469_K	2.377	1.00
493_S	514_R	2.360	1.00
203_F	259_G	2.355	1.00
250_T	257_K	2.354	1.00
280_W	284_I	2.342	1.00
460_M	541_A	2.328	1.00
276_R	280_W	2.322	1.00
476_T	480_N	2.269	1.00
322_R	339_N	2.260	1.00
560_H	564_E	2.246	1.00
546_V	550_R	2.185	1.00
467_Q	533_L	2.167	1.00
322_R	343_E	2.152	1.00
28_S	278_N	2.140	1.00
472_E	535_Q	2.129	1.00
95_K	99_D	2.110	1.00
470_N	473_E	2.110	1.00
467_Q	537_E	2.110	1.00
137_K	141_E	2.108	1.00
163_T	181_D	2.106	1.00
298_K	302_G	2.095	1.00
307_L	311_T	2.067	1.00
493_S	511_D	2.054	1.00
111_T	115_E	2.038	1.00
436_G	566_L	2.003	1.00
201_F	215_P	1.997	1.00
474_V	530_T	1.991	1.00
515_K	518_E	1.975	1.00
313_A	321_V	1.965	1.00
314_V	341_M	1.957	1.00
414_Q	417_E	1.949	1.00
154_D	157_T	1.949	1.00
511_D	514_R	1.944	1.00
477_A	523_S	1.938	1.00
636_T	639_L	1.922	1.00
196_V	200_G	1.909	1.00
465_E	542_S	1.906	1.00
520_S	524_T	1.903	1.00
422_I	580_I	1.886	1.00
229_Q	233_S	1.858	1.00
169_L	174_V	1.856	1.00
468_T	538_T	1.854	1.00
557_S	561_E	1.847	1.00
617_E	620_A	1.845	1.00
463_D	466_N	1.843	1.00
308_I	333_I	1.842	1.00
4_K	7_M	1.831	1.00
361_D	365_Q	1.826	1.00
138_L	141_E	1.811	1.00
339_N	342_V	1.804	1.00
585_A	588_Q	1.763	1.00
201_F	214_H	1.756	1.00
550_R	553_D	1.754	1.00
438_D	442_Q	1.741	1.00
311_T	338_F	1.735	1.00
32_L	274_M	1.733	1.00
159_D	185_S	1.731	1.00
461_L	542_S	1.730	1.00
293_S	297_A	1.725	1.00
400_T	403_E	1.722	1.00
436_G	569_I	1.721	1.00
464_L	541_A	1.717	1.00
461_L	541_A	1.713	1.00
152_Y	181_D	1.711	1.00
610_E	613_A	1.707	1.00
333_I	336_R	1.707	1.00
312_K	337_D	1.703	1.00
479_S	524_T	1.700	1.00
561_E	564_E	1.699	1.00
129_D	132_S	1.696	1.00
142_T	145_Q	1.691	1.00
602_Q	606_A	1.687	1.00
109_I	168_I	1.679	1.00
443_L	562_T	1.678	1.00
435_K	438_D	1.677	1.00
473_E	476_T	1.662	1.00
396_S	399_E	1.662	1.00
466_N	470_N	1.658	1.00
346_K	350_E	1.651	1.00
424_E	428_S	1.648	1.00
364_E	368_A	1.645	1.00
152_Y	163_T	1.642	1.00
226_Q	229_Q	1.642	1.00
606_A	609_Q	1.625	1.00
613_A	617_E	1.624	1.00
14_S	290_I	1.623	1.00
185_S	189_S	1.620	1.00
25_M	29_Y	1.603	1.00
528_S	532_K	1.587	1.00
460_M	540_E	1.585	1.00
312_K	316_A	1.584	1.00
361_D	364_E	1.584	1.00
432_A	568_T	1.583	1.00
197_P	266_Q	1.582	1.00
334_L	338_F	1.576	1.00
186_A	189_S	1.575	1.00
104_V	180_Y	1.573	1.00
150_E	208_S	1.570	1.00
148_W	164_A	1.565	1.00
447_S	555_Q	1.565	1.00
189_S	192_N	1.564	1.00
568_T	571_A	1.563	1.00
311_T	334_L	1.559	1.00
553_D	557_S	1.546	1.00
564_E	568_T	1.544	1.00
56_E	60_K	1.544	1.00
151_P	160_M	1.543	1.00
467_Q	470_N	1.542	1.00
325_S	339_N	1.536	1.00
442_Q	445_M	1.533	1.00
550_R	554_E	1.527	1.00
589_R	592_E	1.523	1.00
314_V	342_V	1.508	1.00
384_I	387_V	1.504	1.00
230_T	235_K	1.502	1.00
25_M	282_S	1.501	1.00
603_S	606_A	1.496	1.00
554_E	557_S	1.496	1.00
595_L	599_E	1.495	1.00
201_F	261_Q	1.491	1.00
431_D	435_K	1.489	1.00
308_I	337_D	1.485	1.00
444_L	563_G	1.476	1.00
456_K	459_T	1.473	1.00
139_A	177_V	1.462	1.00
613_A	616_E	1.455	1.00
264_T	268_M	1.455	1.00
539_K	543_H	1.453	1.00
220_K	224_K	1.447	1.00
197_P	200_G	1.447	1.00
420_G	424_E	1.444	1.00
114_K	131_T	1.432	1.00
623_D	627_V	1.425	1.00
30_L	34_P	1.423	1.00
397_E	603_S	1.421	1.00
427_K	431_D	1.420	1.00
575_S	578_Q	1.418	1.00
624_E	627_V	1.407	1.00
21_V	24_L	1.404	1.00
39_D	43_T	1.400	1.00
210_N	221_N	1.391	1.00
134_P	138_L	1.390	1.00
606_A	610_E	1.386	1.00
202_A	260_T	1.379	1.00
630_D	634_H	1.379	1.00
304_I	334_L	1.377	1.00
29_Y	275_N	1.364	1.00
448_N	452_M	1.358	1.00
596_A	599_E	1.354	1.00
453_E	547_E	1.352	1.00
139_A	165_S	1.351	1.00
365_Q	368_A	1.347	1.00
585_A	589_R	1.344	1.00
237_G	248_Y	1.341	1.00
385_E	389_A	1.336	1.00
20_T	285_A	1.335	1.00
33_K	37_T	1.326	1.00
246_V	259_G	1.326	1.00
522_L	525_K	1.325	1.00
464_L	534_I	1.324	1.00
588_Q	592_E	1.322	1.00
311_T	337_D	1.320	1.00
225_D	229_Q	1.316	1.00
234_E	237_G	1.314	1.00
5_L	331_V	1.314	1.00
322_R	342_V	1.312	1.00
189_S	193_K	1.308	1.00
312_K	340_L	1.306	1.00
403_E	407_S	1.306	1.00
438_D	441_G	1.299	1.00
428_S	431_D	1.298	1.00
307_L	334_L	1.298	1.00
461_L	545_M	1.292	1.00
44_T	48_T	1.289	1.00
386_E	389_A	1.286	1.00
343_E	347_E	1.282	1.00
408_L	594_Q	1.282	1.00
452_M	456_K	1.281	1.00
421_G	424_E	1.279	1.00
571_A	575_S	1.278	1.00
147_V	165_S	1.276	1.00
522_L	526_H	1.270	1.00
431_D	434_Y	1.268	1.00
389_A	392_S	1.268	1.00
525_K	529_E	1.263	1.00
273_K	277_A	1.260	1.00
406_E	410_T	1.258	1.00
22_V	26_L	1.251	1.00
150_E	206_D	1.246	1.00
67_S	146_V	1.246	1.00
170_D	175_I	1.245	1.00
153_K	158_G	1.242	1.00
66_L	180_Y	1.241	1.00
459_T	463_D	1.240	1.00
32_L	36_I	1.230	1.00
272_D	275_N	1.221	1.00
136_Y	140_A	1.221	1.00
616_E	620_A	1.218	1.00
229_Q	232_A	1.215	1.00
144_D	169_L	1.207	1.00
64_I	67_S	1.206	1.00
454_T	552_N	1.205	1.00
146_V	166_K	1.202	1.00
578_Q	582_H	1.202	1.00
299_T	302_G	1.199	1.00
514_R	518_E	1.197	1.00
91_H	95_K	1.190	1.00
445_M	448_N	1.188	1.00
480_N	483_D	1.187	1.00
219_G	222_I	1.183	1.00
116_M	119_Y	1.182	1.00
347_E	351_Q	1.181	1.00
490_L	498_R	1.179	1.00
314_V	338_F	1.177	1.00
462_L	466_N	1.176	1.00
442_Q	561_E	1.174	1.00
446_K	554_E	1.173	1.00
631_K	634_H	1.173	1.00
319_L	349_V	1.170	1.00
108_Y	181_D	1.167	1.00
459_T	462_L	1.166	1.00
338_F	342_V	1.164	1.00
132_S	137_K	1.162	1.00
463_D	540_E	1.161	1.00
417_E	421_G	1.159	1.00
318_D	321_V	1.158	1.00
543_H	547_E	1.157	1.00
165_S	177_V	1.157	1.00
620_A	624_E	1.156	1.00
151_P	206_D	1.154	1.00
609_Q	613_A	1.150	1.00
17_L	20_T	1.149	1.00
627_V	630_D	1.142	1.00
445_M	449_E	1.142	1.00
12_F	296_L	1.136	1.00
86_A	89_L	1.134	1.00
489_A	514_R	1.129	1.00
448_N	560_H	1.126	1.00
404_K	407_S	1.126	1.00
458_E	545_M	1.124	1.00
441_G	445_M	1.122	1.00
291_I	295_F	1.121	1.00
525_K	528_S	1.121	1.00
169_L	172_Q	1.119	1.00
314_V	345_M	1.118	1.00
277_A	280_W	1.116	1.00
574_Q	578_Q	1.115	1.00
231_I	259_G	1.114	1.00
452_M	455_K	1.114	1.00
632_V	639_L	1.113	1.00
63_A	67_S	1.113	1.00
620_A	623_D	1.109	1.00
27_S	31_T	1.105	1.00
460_M	544_A	1.104	1.00
462_L	546_V	1.103	1.00
52_E	251_I	1.101	1.00
450_A	552_N	1.101	1.00
447_S	450_A	1.100	1.00
424_E	427_K	1.097	1.00
279_L	283_L	1.097	1.00
578_Q	581_D	1.096	1.00
96_Q	99_D	1.095	1.00
136_Y	177_V	1.095	1.00
37_T	41_K	1.094	1.00
419_A	422_I	1.094	1.00
582_H	585_A	1.092	1.00
133_R	154_D	1.090	1.00
307_L	338_F	1.090	1.00
502_S	513_V	1.089	1.00
13_V	293_S	1.089	1.00
518_E	522_L	1.085	1.00
486_N	514_R	1.085	1.00
474_V	531_V	1.084	1.00
566_L	569_I	1.083	1.00
319_L	345_M	1.082	1.00
133_R	155_V	1.081	1.00
58_Q	62_Y	1.079	1.00
221_N	224_K	1.079	1.00
314_V	319_L	1.077	1.00
310_K	323_A	1.072	1.00
198_Y	269_W	1.072	1.00
536_L	540_E	1.063	1.00
519_Q	522_L	1.061	1.00
275_N	279_L	1.061	1.00
135_W	181_D	1.057	1.00
393_E	396_S	1.054	1.00
389_A	393_E	1.051	1.00
532_K	536_L	1.050	1.00
307_L	335_T	1.042	1.00
529_E	533_L	1.042	1.00
284_I	288_I	1.039	1.00
442_Q	558_A	1.036	1.00
303_P	327_S	1.036	1.00
159_D	183_K	1.030	1.00
455_K	459_T	1.026	1.00
323_A	339_N	1.026	1.00
206_D	210_N	1.025	1.00
543_H	546_V	1.025	1.00
413_R	417_E	1.024	1.00
521_A	525_K	1.024	1.00
309_V	312_K	1.023	1.00
87_S	91_H	1.022	1.00
226_Q	230_T	1.016	1.00
28_S	32_L	1.015	1.00
308_I	312_K	1.013	1.00
110_G	130_P	1.012	1.00
474_V	523_S	1.009	1.00
519_Q	526_H	1.008	1.00
154_D	181_D	1.007	1.00
433_S	570_T	1.007	1.00
453_E	456_K	1.004	1.00
48_T	52_E	1.004	1.00
437_L	567_N	1.003	1.00
353_R	357_G	1.002	1.00
283_L	287_I	1.001	1.00
63_A	148_W	1.001	1.00
66_L	166_K	1.001	1.00
479_S	528_S	1.001	1.00
408_L	590_M	0.998	1.00
455_K	549_S	0.997	1.00
325_S	335_T	0.996	1.00
203_F	214_H	0.994	1.00
557_S	560_H	0.993	1.00
245_M	264_T	0.991	1.00
240_D	264_T	0.989	1.00
430_E	434_Y	0.988	1.00
396_S	400_T	0.988	1.00
149_T	165_S	0.986	1.00
470_N	526_H	0.985	1.00
17_L	289_T	0.985	1.00
605_S	609_Q	0.983	1.00
110_G	136_Y	0.982	1.00
290_I	294_Y	0.981	1.00
6_H	10_A	0.980	1.00
287_I	291_I	0.976	1.00
10_A	14_S	0.976	1.00
458_E	549_S	0.974	1.00
317_G	334_L	0.974	1.00
334_L	341_M	0.973	1.00
131_T	136_Y	0.973	1.00
350_E	354_L	0.972	1.00
547_E	550_R	0.971	1.00
404_K	408_L	0.971	1.00
25_M	278_N	0.970	1.00
133_R	139_A	0.970	1.00
352_V	359_V	0.970	1.00
297_A	300_I	0.967	1.00
198_Y	266_Q	0.967	1.00
407_S	410_T	0.965	1.00
317_G	341_M	0.960	1.00
464_L	538_T	0.959	1.00
581_D	585_A	0.959	1.00
272_D	276_R	0.957	1.00
416_A	419_A	0.955	1.00
308_I	334_L	0.955	1.00
30_L	33_K	0.954	1.00
483_D	494_I	0.953	1.00
511_D	515_K	0.952	1.00
357_G	361_D	0.949	1.00
149_T	152_Y	0.948	1.00
434_Y	438_D	0.948	1.00
207_A	255_G	0.947	1.00
632_V	636_T	0.947	1.00
313_A	341_M	0.947	1.00
134_P	137_K	0.945	1.00
599_E	603_S	0.945	1.00
474_V	524_T	0.944	1.00
110_G	116_M	0.943	1.00
88_R	92_D	0.941	1.00
135_W	152_Y	0.940	1.00
316_A	340_L	0.939	1.00
153_K	160_M	0.939	1.00
618_V	621_S	0.937	1.00
446_K	449_E	0.931	1.00
406_E	409_S	0.925	1.00
517_A	520_S	0.924	1.00
361_D	368_A	0.924	1.00
325_S	329_D	0.922	1.00
21_V	282_S	0.919	1.00
394_Q	608_S	0.918	1.00
625_Q	629_L	0.917	1.00
227_T	232_A	0.917	1.00
154_D	161_I	0.916	1.00
9_I	13_V	0.915	1.00
350_E	353_R	0.914	1.00
469_K	539_K	0.912	1.00
454_T	545_M	0.910	1.00
564_E	567_N	0.910	1.00
384_I	390_G	0.910	1.00
487_L	494_I	0.909	1.00
306_Q	324_E	0.908	1.00
306_Q	309_V	0.908	1.00
408_L	411_K	0.905	1.00
489_A	513_V	0.903	1.00
305_Q	308_I	0.902	1.00
289_T	293_S	0.902	1.00
457_V	548_A	0.900	1.00
415_I	587_I	0.900	1.00
538_T	541_A	0.899	1.00
135_W	163_T	0.898	1.00
60_K	63_A	0.896	1.00
137_K	140_A	0.895	1.00
328_K	332_G	0.894	1.00
526_H	529_E	0.893	1.00
276_R	279_L	0.893	1.00
114_K	117_F	0.893	1.00
585_A	592_E	0.891	1.00
449_E	551_M	0.890	1.00
394_Q	398_V	0.887	1.00
592_E	596_A	0.887	1.00
311_T	314_V	0.887	1.00
440_L	443_L	0.885	1.00
356_S	363_S	0.884	1.00
451_N	556_N	0.884	1.00
294_Y	298_K	0.883	1.00
230_T	234_E	0.881	1.00
453_E	551_M	0.880	1.00
238_I	241_V	0.878	1.00
407_S	593_E	0.878	1.00
234_E	250_T	0.877	1.00
449_E	452_M	0.877	1.00
348_M	352_V	0.877	1.00
354_L	358_K	0.877	1.00
468_T	474_V	0.877	1.00
398_V	604_I	0.876	1.00
325_S	336_R	0.875	1.00
310_K	338_F	0.873	1.00
364_E	367_T	0.871	0.99
458_E	546_V	0.870	0.99
146_V	164_A	0.868	0.99
625_Q	632_V	0.866	0.99
629_L	639_L	0.866	0.99
37_T	268_M	0.856	0.99
457_V	545_M	0.856	0.99
420_G	588_Q	0.854	0.99
383_A	387_V	0.853	0.99
531_V	535_Q	0.852	0.99
388_A	392_S	0.851	0.99
351_Q	354_L	0.850	0.99
567_N	571_A	0.847	0.99
443_L	559_I	0.844	0.99
403_E	406_E	0.841	0.99
341_M	345_M	0.841	0.99
108_Y	116_M	0.840	0.99
110_G	179_S	0.839	0.99
636_T	640_K	0.838	0.99
614_A	617_E	0.838	0.99
191_V	202_A	0.836	0.99
271_S	275_N	0.835	0.99
92_D	96_Q	0.834	0.99
354_L	357_G	0.834	0.99
338_F	341_M	0.832	0.99
161_I	181_D	0.832	0.99
340_L	343_E	0.831	0.99
582_H	586_E	0.831	0.99
394_Q	401_I	0.830	0.99
432_A	435_K	0.830	0.99
105_A	154_D	0.828	0.99
205_A	259_G	0.827	0.99
383_A	614_A	0.827	0.99
443_L	447_S	0.826	0.99
168_I	175_I	0.826	0.99
48_T	260_T	0.825	0.99
269_W	273_K	0.825	0.99
65_S	68_R	0.824	0.99
436_G	440_L	0.823	0.99
18_I	22_V	0.819	0.99
401_I	408_L	0.819	0.99
474_V	520_S	0.819	0.99
163_T	179_S	0.819	0.99
571_A	574_Q	0.817	0.99
347_E	350_E	0.817	0.99
535_Q	542_S	0.814	0.99
433_S	437_L	0.814	0.99
165_S	179_S	0.814	0.99
608_S	612_A	0.813	0.99
244_K	265_D	0.813	0.99
632_V	640_K	0.812	0.99
427_K	581_D	0.812	0.99
335_T	339_N	0.812	0.99
43_T	46_N	0.812	0.99
138_L	142_T	0.811	0.99
303_P	331_V	0.810	0.99
61_S	64_I	0.810	0.99
126_E	130_P	0.810	0.99
38_E	42_N	0.808	0.99
555_Q	562_T	0.807	0.99
426_S	576_L	0.807	0.99
56_E	253_E	0.806	0.99
410_T	414_Q	0.805	0.99
440_L	566_L	0.805	0.99
70_A	166_K	0.804	0.99
412_I	590_M	0.804	0.99
342_V	346_K	0.804	0.99
306_Q	310_K	0.803	0.99
45_Q	49_Q	0.802	0.99
20_T	289_T	0.801	0.99
203_F	261_Q	0.801	0.99
7_M	11_V	0.801	0.99
541_A	545_M	0.800	0.99
135_W	139_A	0.799	0.99
417_E	420_G	0.799	0.99
360_S	364_E	0.799	0.99
301_T	305_Q	0.798	0.99
164_A	182_L	0.797	0.99
408_L	415_I	0.796	0.99
106_M	119_Y	0.794	0.99
584_Y	588_Q	0.793	0.99
230_T	233_S	0.792	0.99
8_K	327_S	0.789	0.99
529_E	532_K	0.788	0.99
92_D	95_K	0.788	0.99
633_K	637_E	0.786	0.99
135_W	177_V	0.785	0.99
433_S	436_G	0.783	0.99
67_S	166_K	0.783	0.99
118_T	121_K	0.782	0.99
331_V	335_T	0.775	0.99
51_L	54_N	0.775	0.99
399_E	403_E	0.768	0.99
618_V	625_Q	0.768	0.99
470_N	533_L	0.768	0.99
359_V	362_T	0.763	0.99
405_S	601_I	0.763	0.99
246_V	261_Q	0.763	0.99
465_E	469_K	0.762	0.99
617_E	621_S	0.762	0.99
447_S	559_I	0.761	0.99
513_V	519_Q	0.761	0.99
454_T	548_A	0.761	0.99
559_I	562_T	0.759	0.99
241_V	246_V	0.759	0.99
28_S	274_M	0.757	0.99
110_G	135_W	0.757	0.99
548_A	555_Q	0.756	0.99
520_S	530_T	0.754	0.99
57_L	60_K	0.754	0.99
174_V	177_V	0.752	0.99
313_A	316_A	0.752	0.99
447_S	556_N	0.751	0.99
142_T	167_A	0.750	0.98
415_I	419_A	0.749	0.98
273_K	276_R	0.746	0.98
204_L	258_V	0.745	0.98
284_I	291_I	0.745	0.98
363_S	367_T	0.743	0.98
599_E	602_Q	0.742	0.98
475_V	479_S	0.739	0.98
270_I	273_K	0.738	0.98
363_S	366_L	0.736	0.98
551_M	554_E	0.735	0.98
211_L	214_H	0.733	0.98
570_T	574_Q	0.732	0.98
244_K	263_D	0.730	0.98
569_I	572_E	0.729	0.98
188_Q	213_A	0.727	0.98
533_L	537_E	0.726	0.98
63_A	146_V	0.725	0.98
125_A	130_P	0.725	0.98
630_D	633_K	0.725	0.98
228_L	231_I	0.723	0.98
231_I	234_E	0.722	0.98
489_A	493_S	0.722	0.98
611_S	632_V	0.721	0.98
274_M	278_N	0.721	0.98
191_V	204_L	0.721	0.98
402_N	407_S	0.721	0.98
415_I	422_I	0.719	0.98
625_Q	639_L	0.718	0.98
451_N	553_D	0.716	0.98
394_Q	408_L	0.715	0.98
41_K	45_Q	0.715	0.98
386_E	390_G	0.714	0.98
323_A	335_T	0.714	0.98
167_A	174_V	0.713	0.98
47_V	50_S	0.713	0.98
405_S	412_I	0.712	0.98
422_I	429_S	0.712	0.98
552_N	555_Q	0.711	0.98
14_S	18_I	0.711	0.98
391_A	398_V	0.711	0.98
558_A	561_E	0.710	0.98
619_N	622_T	0.708	0.98
51_L	202_A	0.708	0.98
464_L	474_V	0.708	0.98
227_T	231_I	0.706	0.98
29_Y	33_K	0.705	0.98
227_T	239_Q	0.705	0.98
465_E	539_K	0.704	0.98
356_S	359_V	0.703	0.98
534_I	538_T	0.703	0.98
468_T	472_E	0.702	0.98
285_A	289_T	0.701	0.98
102_D	106_M	0.700	0.98
44_T	247_V	0.700	0.98
475_V	527_I	0.699	0.98
404_K	411_K	0.697	0.98
60_K	64_I	0.697	0.98
125_A	128_Y	0.695	0.98
196_V	266_Q	0.694	0.98
536_L	539_K	0.692	0.97
473_E	477_A	0.692	0.97
130_P	136_Y	0.691	0.97
191_V	213_A	0.691	0.97
401_I	600_A	0.690	0.97
408_L	422_I	0.690	0.97
24_L	28_S	0.689	0.97
458_E	541_A	0.689	0.97
248_Y	259_G	0.689	0.97
115_E	129_D	0.688	0.97
483_D	487_L	0.688	0.97
138_L	147_V	0.687	0.97
89_L	92_D	0.686	0.97
635_S	638_T	0.685	0.97
87_S	90_F	0.684	0.97
426_S	573_M	0.684	0.97
305_Q	309_V	0.684	0.97
577_V	581_D	0.682	0.97
228_L	232_A	0.681	0.97
107_A	180_Y	0.681	0.97
407_S	411_K	0.681	0.97
409_S	594_Q	0.680	0.97
29_Y	271_S	0.679	0.97
310_K	314_V	0.675	0.97
149_T	163_T	0.674	0.97
457_V	461_L	0.673	0.97
234_E	257_K	0.673	0.97
429_S	573_M	0.673	0.97
16_M	20_T	0.672	0.97
339_N	343_E	0.672	0.97
132_S	135_W	0.671	0.97
139_A	142_T	0.671	0.97
559_I	569_I	0.667	0.97
411_K	586_E	0.666	0.97
483_D	521_A	0.664	0.97
383_A	618_V	0.662	0.97
384_I	618_V	0.662	0.97
622_T	629_L	0.661	0.97
439_A	561_E	0.660	0.97
308_I	331_V	0.660	0.97
106_M	181_D	0.659	0.97
451_N	455_K	0.658	0.97
85_E	89_L	0.658	0.97
307_L	323_A	0.657	0.97
53_Q	56_E	0.657	0.97
628_T	632_V	0.656	0.97
62_Y	65_S	0.654	0.96
231_I	257_K	0.653	0.96
344_N	347_E	0.652	0.96
538_T	542_S	0.652	0.96
311_T	345_M	0.651	0.96
486_N	493_S	0.651	0.96
332_G	335_T	0.650	0.96
167_A	176_G	0.650	0.96
336_R	339_N	0.649	0.96
52_E	56_E	0.647	0.96
391_A	611_S	0.647	0.96
199_K	263_D	0.646	0.96
533_L	536_L	0.646	0.96
111_T	114_K	0.646	0.96
168_I	176_G	0.645	0.96
439_A	442_Q	0.644	0.96
575_S	579_G	0.643	0.96
464_L	555_Q	0.643	0.96
297_A	304_I	0.643	0.96
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129_D	133_R	0.642	0.96
487_L	515_K	0.642	0.96
129_D	136_Y	0.641	0.96
358_K	361_D	0.639	0.96
154_D	158_G	0.639	0.96
27_S	281_I	0.639	0.96
435_K	561_E	0.638	0.96
295_F	298_K	0.637	0.96
105_A	161_I	0.636	0.96
604_I	611_S	0.636	0.96
475_V	528_S	0.635	0.96
355_S	358_K	0.635	0.96
397_E	600_A	0.634	0.96
502_S	507_A	0.633	0.96
463_D	467_Q	0.633	0.96
484_Q	512_E	0.633	0.96
106_M	120_P	0.632	0.96
310_K	321_V	0.632	0.96
102_D	105_A	0.632	0.96
214_H	217_N	0.631	0.96
437_L	441_G	0.629	0.96
149_T	154_D	0.629	0.96
268_M	271_S	0.627	0.96
329_D	335_T	0.627	0.96
66_L	164_A	0.627	0.96
210_N	213_A	0.625	0.95
88_R	91_H	0.624	0.95
90_F	94_I	0.623	0.95
390_G	394_Q	0.622	0.95
110_G	128_Y	0.621	0.95
468_T	534_I	0.620	0.95
38_E	270_I	0.619	0.95
607_I	611_S	0.619	0.95
8_K	299_T	0.616	0.95
440_L	444_L	0.616	0.95
443_L	450_A	0.615	0.95
17_L	293_S	0.615	0.95
315_S	340_L	0.615	0.95
154_D	163_T	0.615	0.95
302_G	305_Q	0.615	0.95
152_Y	155_V	0.615	0.95
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415_I	573_M	0.614	0.95
6_H	301_T	0.614	0.95
250_T	255_G	0.613	0.95
620_A	627_V	0.612	0.95
560_H	563_G	0.612	0.95
21_V	289_T	0.611	0.95
461_L	465_E	0.611	0.95
479_S	525_K	0.611	0.95
474_V	480_N	0.610	0.95
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341_M	344_N	0.609	0.95
325_S	332_G	0.609	0.95
312_K	315_S	0.609	0.95
606_A	613_A	0.609	0.95
139_A	167_A	0.609	0.95
55_I	256_W	0.604	0.95
589_R	593_E	0.604	0.95
317_G	348_M	0.603	0.94
52_E	249_Q	0.602	0.94
433_S	450_A	0.601	0.94
402_N	598_S	0.599	0.94
555_Q	594_Q	0.599	0.94
132_S	155_V	0.598	0.94
48_T	250_T	0.597	0.94
423_K	426_S	0.595	0.94
62_Y	104_V	0.595	0.94
627_V	631_K	0.594	0.94
408_L	593_E	0.594	0.94
153_K	157_T	0.593	0.94
93_D	96_Q	0.593	0.94
127_D	133_R	0.593	0.94
252_G	255_G	0.592	0.94
440_L	559_I	0.592	0.94
39_D	270_I	0.592	0.94
540_E	543_H	0.591	0.94
475_V	524_T	0.590	0.94
225_D	228_L	0.590	0.94
421_G	579_G	0.590	0.94
138_L	165_S	0.588	0.94
477_A	517_A	0.588	0.94
126_E	129_D	0.588	0.94
416_A	591_S	0.587	0.94
407_S	416_A	0.587	0.94
440_L	562_T	0.587	0.94
406_E	411_K	0.586	0.94
124_F	127_D	0.585	0.94
394_Q	404_K	0.584	0.93
399_E	402_N	0.584	0.93
342_V	345_M	0.583	0.93
489_A	518_E	0.581	0.93
408_L	597_I	0.580	0.93
362_T	365_Q	0.579	0.93
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430_E	577_V	0.578	0.93
46_N	49_Q	0.578	0.93
298_K	305_Q	0.578	0.93
11_V	14_S	0.577	0.93
483_D	493_S	0.575	0.93
454_T	457_V	0.574	0.93
110_G	177_V	0.574	0.93
457_V	544_A	0.574	0.93
387_V	391_A	0.573	0.93
563_G	567_N	0.573	0.93
443_L	513_V	0.573	0.93
541_A	544_A	0.572	0.93
130_P	133_R	0.572	0.93
484_Q	519_Q	0.572	0.93
395_A	609_Q	0.571	0.93
252_G	256_W	0.571	0.93
212_L	256_W	0.571	0.93
426_S	436_G	0.570	0.93
480_N	519_Q	0.569	0.93
462_L	465_E	0.568	0.93
474_V	477_A	0.568	0.93
128_Y	135_W	0.568	0.93
56_E	255_G	0.567	0.92
429_S	440_L	0.567	0.92
136_Y	163_T	0.566	0.92
400_T	404_K	0.566	0.92
406_E	598_S	0.566	0.92
428_S	432_A	0.565	0.92
587_I	590_M	0.565	0.92
135_W	179_S	0.565	0.92
423_K	427_K	0.565	0.92
200_G	266_Q	0.563	0.92
405_S	408_L	0.562	0.92
144_D	167_A	0.562	0.92
456_K	544_A	0.562	0.92
138_L	145_Q	0.561	0.92
152_Y	161_I	0.560	0.92
628_T	631_K	0.560	0.92
196_V	260_T	0.560	0.92
86_A	90_F	0.559	0.92
395_A	398_V	0.559	0.92
124_F	129_D	0.559	0.92
583_I	590_M	0.559	0.92
611_S	614_A	0.558	0.92
335_T	341_M	0.557	0.92
165_S	181_D	0.557	0.92
31_T	34_P	0.555	0.92
352_V	356_S	0.554	0.92
632_V	635_S	0.554	0.92
464_L	625_Q	0.554	0.92
535_Q	539_K	0.552	0.91
397_E	400_T	0.552	0.91
36_I	40_G	0.551	0.91
127_D	131_T	0.550	0.91
559_I	563_G	0.550	0.91
301_T	331_V	0.550	0.91
429_S	576_L	0.549	0.91
489_A	511_D	0.548	0.91
303_P	332_G	0.547	0.91
411_K	415_I	0.547	0.91
386_E	610_E	0.547	0.91
410_T	589_R	0.546	0.91
435_K	565_V	0.546	0.91
402_N	411_K	0.545	0.91
10_A	15_I	0.544	0.91
116_M	130_P	0.544	0.91
486_N	489_A	0.544	0.91
315_S	334_L	0.543	0.91
465_E	538_T	0.542	0.91
42_N	46_N	0.542	0.91
67_S	71_N	0.541	0.91
59_L	164_A	0.541	0.91
460_M	538_T	0.541	0.91
18_I	286_L	0.540	0.91
51_L	59_L	0.540	0.91
172_Q	176_G	0.539	0.90
572_E	576_L	0.539	0.90
579_G	582_H	0.539	0.90
5_L	304_I	0.537	0.90
434_Y	437_L	0.536	0.90
468_T	541_A	0.536	0.90
410_T	413_R	0.536	0.90
72_G	93_D	0.535	0.90
394_Q	397_E	0.534	0.90
388_A	391_A	0.534	0.90
263_D	266_Q	0.534	0.90
601_I	605_S	0.534	0.90
195_K	266_Q	0.531	0.90
455_K	553_D	0.531	0.90
145_Q	167_A	0.531	0.90
483_D	513_V	0.530	0.90
579_G	583_I	0.529	0.90
409_S	598_S	0.529	0.90
231_I	248_Y	0.529	0.90
195_K	200_G	0.529	0.90
111_T	117_F	0.529	0.90
531_V	541_A	0.529	0.90
58_Q	61_S	0.528	0.90
394_Q	405_S	0.527	0.89
615_A	622_T	0.527	0.89
209_G	221_N	0.526	0.89
56_E	251_I	0.526	0.89
315_S	337_D	0.525	0.89
384_I	615_A	0.525	0.89
576_L	580_I	0.524	0.89
133_R	153_K	0.522	0.89
37_T	40_G	0.522	0.89
188_Q	192_N	0.521	0.89
422_I	576_L	0.518	0.89
559_I	566_L	0.518	0.89
548_A	552_N	0.518	0.89
635_S	639_L	0.517	0.89
419_A	583_I	0.517	0.89
124_F	130_P	0.517	0.89
479_S	483_D	0.517	0.89
106_M	156_V	0.516	0.88
418_E	582_H	0.516	0.88
404_K	593_E	0.516	0.88
203_F	211_L	0.514	0.88
395_A	403_E	0.513	0.88
411_K	589_R	0.513	0.88
128_Y	131_T	0.512	0.88
450_A	576_L	0.512	0.88
471_I	524_T	0.512	0.88
94_I	98_K	0.512	0.88
566_L	576_L	0.511	0.88
383_A	390_G	0.509	0.88
335_T	338_F	0.509	0.88
436_G	562_T	0.509	0.88
268_M	272_D	0.507	0.88
409_S	412_I	0.507	0.88
429_S	436_G	0.507	0.88
76_H	170_D	0.506	0.88
595_L	598_S	0.506	0.88
634_H	637_E	0.506	0.88
398_V	405_S	0.506	0.88
613_A	620_A	0.505	0.87
106_M	110_G	0.504	0.87
34_P	38_E	0.503	0.87
66_L	70_A	0.502	0.87
62_Y	180_Y	0.501	0.87
14_S	17_L	0.501	0.87
470_N	530_T	0.500	0.87

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3zx6A	2	0.4611	100	0.514	Contact Map
2ch7A	2	0.4718	100	0.591	Contact Map
1qu7A	2	0.342	100	0.621	Contact Map
3g67A	2	0.3191	100	0.672	Contact Map
4i3mA	2	0.2244	99.9	0.795	Contact Map
3lifA	1	0.3573	99.9	0.808	Contact Map
3lidA	2	0.3786	99.9	0.81	Contact Map
3e4oA	2	0.3344	99.9	0.813	Contact Map
3li9A	2	0.3389	99.9	0.824	Contact Map
3c8cA	2	0.3527	99.9	0.825	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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