GREMLIN Database
YQJY - Uncharacterized protein YqjY
UniProt: P54562 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 156 (128)
Sequences: 9064 (7099)
Seq/√Len: 627.5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
4_R47_S3.5141.00
20_E76_H3.2881.00
93_I124_F2.8941.00
86_K121_K2.6991.00
53_T79_F2.3311.00
56_L92_F2.3051.00
46_T84_I2.2661.00
86_K122_L2.2171.00
90_D122_L2.0811.00
45_I52_M2.0131.00
48_E79_F1.9891.00
44_F91_V1.9771.00
91_V94_E1.8771.00
113_K117_A1.8711.00
6_I14_V1.8291.00
58_G92_F1.8191.00
79_F82_M1.8031.00
4_R10_D1.7951.00
13_M16_S1.7101.00
20_E77_P1.7071.00
48_E53_T1.6691.00
48_E82_M1.6311.00
89_Y122_L1.6301.00
21_W74_G1.5931.00
117_A120_T1.5741.00
93_I104_V1.5491.00
126_I129_G1.5431.00
15_T19_N1.5421.00
95_T98_Q1.5381.00
95_T99_R1.5121.00
116_I120_T1.5111.00
120_T126_I1.4971.00
80_R114_V1.4661.00
68_A96_V1.4601.00
54_G75_V1.3831.00
12_E29_E1.3081.00
60_Q101_C1.3031.00
106_C119_H1.3021.00
44_F95_T1.2961.00
43_S57_I1.2891.00
16_S20_E1.2871.00
86_K90_D1.2851.00
51_S78_D1.2701.00
6_I45_I1.2541.00
47_S50_N1.2501.00
91_V95_T1.2361.00
51_S76_H1.2321.00
115_S119_H1.1971.00
96_V104_V1.1581.00
17_V21_W1.1581.00
47_S52_M1.1511.00
13_M52_M1.1501.00
20_E78_D1.1411.00
27_L31_L1.1311.00
10_D47_S1.1151.00
42_T99_R1.1111.00
42_T95_T1.1091.00
76_H79_F1.0971.00
6_I43_S1.0811.00
110_P129_G1.0731.00
108_T115_S1.0681.00
30_K34_L1.0531.00
116_I126_I1.0451.00
3_I44_F1.0451.00
21_W80_R1.0411.00
48_E51_S1.0411.00
56_L70_I1.0321.00
56_L88_L1.0271.00
16_S76_H1.0101.00
17_V52_M0.9951.00
75_V84_I0.9741.00
83_Q86_K0.9681.00
17_V76_H0.9661.00
106_C115_S0.9421.00
58_G96_V0.9351.00
113_K116_I0.9311.00
28_K31_L0.9311.00
53_T84_I0.9311.00
93_I122_L0.9281.00
29_E33_R0.9251.00
42_T58_G0.9241.00
33_R37_E0.9221.00
70_I89_Y0.9221.00
18_L55_F0.9111.00
112_N115_S0.9061.00
13_M17_V0.9021.00
46_T54_G0.9011.00
3_I87_Q0.8921.00
22_W74_G0.8841.00
94_E98_Q0.8811.00
13_M51_S0.8581.00
26_Q32_P0.8251.00
96_V101_C0.8171.00
108_T112_N0.8161.00
12_E16_S0.8151.00
89_Y118_Y0.8141.00
68_A101_C0.8091.00
17_V74_G0.8081.00
28_K32_P0.8071.00
25_R30_K0.8061.00
27_L32_P0.8021.00
89_Y119_H0.8001.00
13_M76_H0.7951.00
87_Q90_D0.7901.00
51_S79_F0.7841.00
14_V55_F0.7811.00
31_L35_F0.7721.00
118_Y122_L0.7711.00
30_K36_F0.7611.00
5_T95_T0.7581.00
73_S119_H0.7561.00
3_I91_V0.7551.00
11_Y15_T0.7551.00
38_H41_D0.7511.00
8_S37_E0.7501.00
90_D94_E0.7431.00
55_F74_G0.7381.00
105_K127_E0.7371.00
81_K114_V0.7301.00
5_T44_F0.7301.00
57_I71_H0.7281.00
18_L22_W0.7281.00
21_W77_P0.7171.00
75_V85_G0.7141.00
67_T105_K0.7101.00
27_L35_F0.7051.00
69_Y105_K0.6881.00
32_P35_F0.6871.00
69_Y107_V0.6721.00
46_T53_T0.6701.00
27_L34_L0.6641.00
84_I87_Q0.6591.00
93_I97_K0.6581.00
27_L30_K0.6521.00
4_R7_T0.6501.00
35_F57_I0.6481.00
34_L39_F0.6451.00
104_V124_F0.6401.00
128_K131_K0.6291.00
33_R36_F0.6261.00
42_T60_Q0.6261.00
77_P80_R0.6251.00
26_Q34_L0.6241.00
18_L72_F0.6211.00
67_T103_R0.6151.00
29_E32_P0.6131.00
106_C124_F0.6121.00
61_S64_D0.6111.00
59_F71_H0.6101.00
81_K117_A0.6091.00
13_M45_I0.6091.00
64_D67_T0.6051.00
16_S51_S0.6051.00
111_V116_I0.6041.00
54_G88_L0.6011.00
26_Q29_E0.5891.00
32_P36_F0.5891.00
60_Q99_R0.5841.00
85_G118_Y0.5821.00
35_F38_H0.5821.00
30_K33_R0.5801.00
5_T42_T0.5801.00
26_Q30_K0.5781.00
31_L34_L0.5751.00
25_R35_F0.5711.00
16_S19_N0.5601.00
108_T116_I0.5541.00
73_S89_Y0.5521.00
34_L38_H0.5481.00
58_G95_T0.5420.99
56_L73_S0.5390.99
46_T88_L0.5380.99
59_F62_Q0.5370.99
26_Q36_F0.5330.99
35_F41_D0.5310.99
25_R31_L0.5260.99
43_S47_S0.5240.99
3_I88_L0.5240.99
25_R28_K0.5240.99
73_S115_S0.5220.99
12_E15_T0.5180.99
94_E97_K0.5180.99
108_T119_H0.5160.99
79_F84_I0.5160.99
120_T125_D0.5150.99
25_R29_E0.5120.99
69_Y72_F0.5110.99
114_V117_A0.5080.99
64_D105_K0.5070.99
22_W72_F0.5040.99
54_G84_I0.5030.99
112_N119_H0.5000.99
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1mk4A 2 1 99.9 0.308 Contact Map
3d3sA 2 0.9936 99.9 0.341 Contact Map
4kvxA 1 0.9295 99.9 0.347 Contact Map
3dr6A 2 0.9615 99.9 0.358 Contact Map
2reeA 1 0.9679 99.9 0.358 Contact Map
1s3zA 2 0.8782 99.9 0.364 Contact Map
2r7hA 2 0.9423 99.9 0.364 Contact Map
2j8mA 2 0.9615 99.9 0.367 Contact Map
4pv6C 3 0.9231 99.9 0.371 Contact Map
2ob0A 1 0.9423 99.9 0.377 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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