GREMLIN Database
YQJT - Uncharacterized protein YqjT
UniProt: P54557 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 128 (124)
Sequences: 539 (406)
Seq/√Len: 36.5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
81_D109_Y3.7731.00
84_T100_H3.5331.00
76_S79_Q3.3821.00
18_W121_V3.0071.00
80_V109_Y2.8551.00
10_D13_A2.8291.00
15_R32_K2.6891.00
94_V100_H2.6671.00
17_F116_P2.6121.00
15_R37_I2.6011.00
13_A117_D2.5971.00
1_M4_I2.4421.00
96_Y120_K2.3861.00
14_S115_D2.2200.99
84_T94_V2.1910.99
87_L113_C1.9320.98
77_K81_D1.9050.98
4_I70_L1.8880.98
19_G39_W1.8460.97
51_A65_V1.8310.97
115_D119_I1.7710.97
94_V111_V1.6000.94
5_E36_G1.5640.93
87_L111_V1.5420.93
7_Y68_N1.4620.91
29_E32_K1.4570.91
7_Y112_F1.4230.90
29_E37_I1.4100.89
7_Y51_A1.3910.88
5_E45_Y1.3810.88
58_P64_R1.3810.88
1_M44_F1.3770.88
85_E89_A1.3660.87
74_A123_L1.3330.86
49_V120_K1.2660.83
13_A16_R1.2550.83
105_G120_K1.2540.83
79_Q82_Q1.2260.81
99_R112_F1.2230.81
83_M123_L1.2170.81
85_E88_T1.2040.80
24_E86_K1.1640.77
61_H64_R1.1540.77
84_T111_V1.1470.76
88_T97_R1.1430.76
78_L82_Q1.1080.74
36_G45_Y1.1070.74
51_A56_L1.0780.72
96_Y101_P1.0780.72
19_G29_E1.0740.72
95_L120_K1.0720.71
30_Y40_K1.0720.71
80_V84_T1.0640.71
87_L92_Y1.0620.71
33_W105_G1.0610.71
10_D78_L1.0550.70
1_M72_F1.0410.69
82_Q89_A1.0290.68
51_A55_F1.0280.68
86_K89_A0.9910.65
71_A120_K0.9730.64
45_Y62_R0.9680.63
28_K34_S0.9430.61
2_H105_G0.9410.61
67_L70_L0.9410.61
31_Q38_S0.9340.61
55_F61_H0.9330.60
29_E83_M0.9290.60
17_F115_D0.9230.60
5_E33_W0.9190.59
12_E35_S0.9070.58
33_W47_V0.9030.58
14_S19_G0.8650.55
99_R103_A0.8540.54
102_F108_H0.8520.54
96_Y99_R0.8460.53
23_K70_L0.8160.50
80_V125_A0.8150.50
98_D104_G0.8130.50
38_S47_V0.8070.50
55_F118_R0.8050.49
4_I86_K0.8020.49
74_A80_V0.7990.49
95_L101_P0.7970.49
57_E64_R0.7890.48
84_T102_F0.7790.47
48_I84_T0.7770.47
18_W39_W0.7760.47
22_L27_Y0.7710.46
59_E65_V0.7680.46
33_W68_N0.7640.46
32_K37_I0.7510.45
53_E97_R0.7500.45
27_Y72_F0.7390.44
33_W103_A0.7380.44
29_E64_R0.7340.43
68_N101_P0.7320.43
111_V119_I0.7310.43
18_W23_K0.7280.43
20_W24_E0.7210.42
92_Y113_C0.7180.42
33_W100_H0.7160.42
7_Y120_K0.7160.42
84_T98_D0.7140.42
7_Y49_V0.7120.41
75_E88_T0.7100.41
78_L97_R0.7080.41
33_W45_Y0.7070.41
46_L70_L0.7070.41
18_W115_D0.7050.41
30_Y38_S0.7030.41
13_A115_D0.6990.40
76_S82_Q0.6980.40
34_S59_E0.6950.40
24_E79_Q0.6940.40
2_H125_A0.6920.40
6_L61_H0.6910.40
62_R95_L0.6910.40
2_H110_A0.6830.39
82_Q86_K0.6810.39
16_R85_E0.6750.38
1_M56_L0.6630.37
10_D58_P0.6610.37
11_L34_S0.6560.37
17_F92_Y0.6500.36
33_W36_G0.6450.36
77_K82_Q0.6440.36
6_L34_S0.6420.36
46_L107_G0.6400.35
8_V117_D0.6350.35
92_Y111_V0.6330.35
62_R124_V0.6290.35
8_V32_K0.6280.34
9_S50_Q0.6270.34
4_I56_L0.6230.34
33_W101_P0.6220.34
100_H111_V0.6130.33
56_L82_Q0.6110.33
11_L50_Q0.6110.33
75_E79_Q0.6090.33
26_G106_D0.6080.33
71_A95_L0.6040.33
80_V88_T0.6000.32
28_K42_D0.6000.32
85_E93_R0.5930.32
9_S117_D0.5870.31
7_Y118_R0.5850.31
12_E15_R0.5830.31
48_I65_V0.5800.31
42_D53_E0.5770.31
4_I33_W0.5760.30
27_Y62_R0.5760.30
27_Y73_H0.5720.30
61_H65_V0.5700.30
4_I67_L0.5690.30
45_Y105_G0.5640.30
92_Y99_R0.5610.29
82_Q85_E0.5600.29
23_K78_L0.5590.29
62_R71_A0.5590.29
36_G105_G0.5590.29
5_E49_V0.5570.29
6_L37_I0.5550.29
80_V111_V0.5540.29
94_V109_Y0.5510.29
104_G108_H0.5480.28
16_R76_S0.5460.28
21_F123_L0.5450.28
54_P118_R0.5290.27
105_G125_A0.5280.27
6_L16_R0.5280.27
24_E102_F0.5270.27
95_L114_E0.5260.27
88_T99_R0.5220.27
62_R120_K0.5210.27
56_L61_H0.5210.27
12_E16_R0.5200.26
101_P104_G0.5190.26
24_E108_H0.5180.26
101_P105_G0.5150.26
62_R70_L0.5130.26
7_Y96_Y0.5060.26
98_D102_F0.5060.26
16_R99_R0.5010.25
37_I54_P0.5000.25
59_E82_Q0.5000.25
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3ct8A 2 0.9766 99.9 0.542 Contact Map
4z04A 2 0.9375 99.8 0.585 Contact Map
4qb5A 2 0.9531 99.8 0.614 Contact Map
1xqaA 2 0.8359 99.7 0.624 Contact Map
2rk0A 4 0.9297 99.7 0.626 Contact Map
3e5dA 2 0.9141 99.7 0.63 Contact Map
3huhA 2 0.9375 99.7 0.635 Contact Map
3rriA 3 0.9375 99.7 0.637 Contact Map
3ey7A 2 0.9531 99.7 0.637 Contact Map
4mymA 2 0.9531 99.7 0.64 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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